683 results on '"Ziranu, A"'
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2. Megaprosthetic replacement in complex distal humerus fractures in elderly patients: a case series
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Caredda, Matteo, Cianni, Luigi, De Fazio, Andrea, Ziranu, Antonio, Vitiello, Raffaele, and Maccauro, Giulio
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- 2024
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3. Artificial Intelligence in Musculoskeletal Oncology
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Vitiello, Raffaele, Ziranu, Antonio, Maccauro, Giulio, Familiari, Filippo, editor, Galasso, Olimpio, editor, and Gasparini, Giorgio, editor
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- 2024
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4. Megaprosthetic replacement in complex distal humerus fractures in elderly patients: a case series
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Matteo Caredda, Luigi Cianni, Andrea De Fazio, Antonio Ziranu, Raffaele Vitiello, and Giulio Maccauro
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Megaprostheses ,Megaprosthesis ,Elbow ,Elderly ,Elbow replacement ,Distal humerus ,Orthopedic surgery ,RD701-811 ,Diseases of the musculoskeletal system ,RC925-935 - Abstract
Abstract Background Managing distal humeral fractures can be challenging for orthopedic surgeons. There are several treatment options for managing this type of fracture, and the treatment method for these fractures should be based on patient-related factors. In elderly patients with osteoporotic bone and severe comminution of the fracture, adequate fixation can be a major challenge for surgeons. The use of megaprosthesis has been recently proposed in traumatology as an alternative to osteosynthesis or conventional prosthesis for the management of comminuted articular fractures in elderly patients with poor bone stock. Methods A consecutive case series of 5 patients who underwent reconstruction of the elbow joint with a trabecular hinged modular elbow megaprosthesis was reviewed retrospectively. All patients included had AO/OTA 13C2 and 13C3 fractures with metaphyseal extension and considerable bone loss of the distal humerus. The primary outcome was the evaluation of functional and clinical outcomes with the MEPS score in comminuted distal humerus fractures with metaphyseal extension and poor bone stock in elderly patients treated with elbow megaprosthesis. The secondary outcome was assessing the treatment-related complication rate of this technique in non-oncological fields. Results Five patients were included in the study with a mean age of 82.66 ± 7.72 years at surgery. The mean MEPS value was 63 ± 24.2 at 1 month, 81 ± 23.53 at 3 months, 83 ± 24.2 at 6 months, and 84 ± 24.57 at 12 months. No intraoperative complications were recorded in our series. Of 5 patients, four patients had excellent clinical and functional outcomes. We did not encounter wound dehiscence, prosthetic joint infection, aseptic loosening, or periprosthetic fractures. Conclusions The indication for this type of treatment must be selected and narrowed down, as it is a salvage procedure, and any failure would cause even more complex situations. Short operating times and early mobilization of the elbow are the advantages of this technique.
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- 2024
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5. Mismatch Repair system protein deficiency as a resistance factor for locally advanced rectal adenocarcinoma patients receiving neoadjuvant chemo-radiotherapy
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Pretta, Andrea, Ziranu, Pina, Giampieri, Riccardo, Pinna, Giovanna, Randon, Giovanni, Donisi, Clelia, Ravarino, Alberto, Loi, Francesco, Deias, Giulia, Palmas, Enrico, Pretta, Gianluca, Morano, Federica, Semonella, Francesca, Mariani, Stefano, Deidda, Maria Assunta, Pusceddu, Valeria, Puzzoni, Marco, Lai, Eleonora, Solinas, Cinzia, Restivo, Angelo, Zorcolo, Luigi, Barbara, Raffaele, Berardi, Rossana, Faa, Gavino, Pietrantonio, Filippo, and Scartozzi, Mario
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- 2023
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6. The correlation between L1CAM expression and outcomes in patients with metastatic colorectal cancer treated with first-line chemotherapy.
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Pretta, Andrea, Cau, Flaviana, Ziranu, Pina, Spanu, Dario, Donisi, Clelia, Moledda, Giusy, Cadoni, Andrea, Cimbro, Erika, Murgia, Sara, Mariani, Stefano, Lai, Eleonora, Puzzoni, Marco, Pusceddu, Valeria, Faa, Gavino, and Scartozzi, Mario
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- 2024
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7. Clinical characteristics and outcomes in patients with early-onset locally advanced rectal cancer.
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Pretta, Andrea, Ziranu, Pina, Giampieri, Riccardo, Donisi, Clelia, Randon, Giovanni, Moledda, Giusy, Morano, Federica, Spanu, Dario, Cadoni, Andrea, Cimbro, Erika, DellʼUtri, Veronica, Rizzo, Daiana, Codipietro, Claudia, Semonella, Francesca, Puzzoni, Marco, Pusceddu, Valeria, Zorcolo, Luigi, Berardi, Rossana, Pietrantonio, Filippo, and Scartozzi, Mario
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- 2024
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8. CDX-2 expression correlates with clinical outcomes in MSI-H metastatic colorectal cancer patients receiving immune checkpoint inhibitors
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Ziranu, Pina, Pretta, Andrea, Pozzari, Marta, Maccioni, Antonio, Badiali, Manuela, Fanni, Daniela, Lai, Eleonora, Donisi, Clelia, Persano, Mara, Gerosa, Clara, Puzzoni, Marco, Bardanzellu, Fabio, Ambu, Rossano, Pusceddu, Valeria, Dubois, Marco, Cerrone, Giulia, Migliari, Marco, Murgia, Sara, Spanu, Dario, Pretta, Gianluca, Aimola, Valentina, Balconi, Francesca, Murru, Stefania, Faa, Gavino, and Scartozzi, Mario
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- 2023
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9. Editorial: Angiogenesis and access to vasculature as a target in gastrointestinal tumors and predictive biomarkers identification: an open challenge
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Eleonora Lai, Pina Ziranu, Francesco Pezzella, Andrea Pretta, Nicole Liscia, and Zhiwei Hu
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tumor angiogenesis ,gastrointestinal cancer ,predictive biomarkers ,anti-angiogenic agents ,treatment resistance ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Published
- 2024
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10. Immunonutrition supplementation for resectable gastric cancer during standard neoadjuvant chemotherapy of FLOT. A proof-of-concept protocol: I-SUPPLY
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V. Pusceddu, C. Donisi, A. Pretta, F. Loi, R. Badas, P. Ziranu, M. Puzzoni, E. Lai, S. Mariani, E. Palmas, M. Pozzari, E. Cimbro, A.P. D’Agata, S. Pinto, F. Coghe, S. Bergamini, D. Fanni, G. Faa, T. Yoshino, and M. Scartozzi
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immunonutrition supplementation ,Immunoscore ,immune nutrients ,gastric cancer ,tumour microenvironment ,perioperative chemotherapy ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
The ‘immune pattern’ of the esophagogastric junction and gastric cancer (GC) has been related to tumour progression and/or response to therapies. GC can be classified as immunogenic or immune-resistant based on the infiltration of the tumour microenvironment (TME) from different immune cells (ICs), the most significant of which are activated lymphocytes (a-Ly) CD8+ and CD4+. From the amount of a-Ly infiltration in TME, we can identify tumours with high Immunoscore (IS) which correlates with better prognosis in terms of disease-free survival and overall survival (OS). IC activation and consequent immunogenic TME requires high nutrient absorption and synthesis and accumulation of protein, lipid, and nucleotides. However, tumour cells (TCs) promote their own proliferation by stealing micronutrients to ICs, therefore leading to an immunosuppressive TME phenotype. This proof-of-concept protocol aims to assess whether a controlled enteral immune nutrition (EIN) supplementation can revert the TME in favour of ICs over TCs, in both auxotrophic and non-auxotrophic malignancies, witnessed by an increase in IS in surgical specimen over biopsy controls. Secondary endpoints are: (i) tumour regression grade assessment compared to historical data from FLOT4/AIO; (ii) combined proportion score ratio; (iii) relapse-free survival at 3 years and OS; and (iv) quality of life by the European Organisation for Research and Treatment of Cancer quality-of-life questionnaire (EORTC QLQ)-30.
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- 2024
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11. Functional Outcomes and Shoulder Instability in Reconstruction of Proximal Humerus Metastases
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Alessandro El Motassime, Cesare Meschini, Doriana Di Costa, Giuseppe Rovere, Maria Rosaria Matrangolo, Fernando De Maio, Pasquale Farsetti, Antonio Ziranu, Giulio Maccauro, and Raffaele Vitiello
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shoulder ,megaprosthesis ,functional outcome ,proximal humerus ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
(1) Background: Some of the goals of orthopedic surgical oncology are saving limbs and function. The humerus is the third most frequent site in primary tumors and one of the most involved sites for metastases. Prosthetic replacement with modular megaprosthesis is one of the treatment choices, but there are several types of complications, such as problems with function and pain. The aim of our study is to assess functional outcomes and shoulder instability in the reconstruction of proximal humerus metastases. (2) Methods: This is a retrospective observational study. Twenty-eight patients, with proximal humerus metastases, admitted to the department of Orthopaedics and Traumatology of our University Hospital between 2014 and 2022 were recruited. Each patient underwent resection and prosthetic replacement surgery with modular megaprosthesis. Clinical evaluation was assessed through MSTS score, WOSI index, and DASH score. (3) Results: Twenty patients were included in the study. Fairly good results, especially regarding pain, function, and emotional acceptance, were obtained in all three tests: DASH, MSTS, and WOSI. Patients who reported shoulder instability actually have worse outcomes than those who report having stable shoulders. In addition, patients with a resection >10 cm have worse outcomes than those who had a resection of 10 cm. No significant differences were found between the deltopectoral approach group and the lateral approach group. (4) Conclusions: Reconstructive surgery with megaprosthesis of the proximal humerus in patients with metastases can be considered a treatment option, especially in patients with pathological fractures or injuries with a high risk of fracture and good life expectancy. This study shows how this type of surgery affects instability, but in terms of functionality, pain, and patient satisfaction, it gives satisfactory results.
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- 2023
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12. CDX-2 expression correlates with clinical outcomes in MSI-H metastatic colorectal cancer patients receiving immune checkpoint inhibitors
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Pina Ziranu, Andrea Pretta, Marta Pozzari, Antonio Maccioni, Manuela Badiali, Daniela Fanni, Eleonora Lai, Clelia Donisi, Mara Persano, Clara Gerosa, Marco Puzzoni, Fabio Bardanzellu, Rossano Ambu, Valeria Pusceddu, Marco Dubois, Giulia Cerrone, Marco Migliari, Sara Murgia, Dario Spanu, Gianluca Pretta, Valentina Aimola, Francesca Balconi, Stefania Murru, Gavino Faa, and Mario Scartozzi
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Medicine ,Science - Abstract
Abstract Immune checkpoint inhibitors (ICIs) showed efficacy in metastatic colorectal cancer (mCRC) with mismatch-repair deficiency or high microsatellite instability (dMMR-MSI-H). Unfortunately, a patient’s subgroup did not benefit from immunotherapy. Caudal-related homeobox transcription factor 2 (CDX-2) would seem to influence immunotherapy’s sensitivity, promoting the chemokine (C-X-C motif) ligand 14 (CXCL14) expression. Therefore, we investigated CDX-2 role as a prognostic-predictive marker in patients with mCRC MSI-H. We retrospectively collected data from 14 MSI-H mCRC patients treated with ICIs between 2019 and 2021. The primary endpoint was the 12-month progression-free-survival (PFS) rate. The secondary endpoints were overall survival (OS), PFS, objective response rate (ORR), and disease control rate (DCR). The PFS rate at 12 months was 81% in CDX-2 positive patients vs 0% in CDX-2 negative patients (p = 0.0011). The median PFS was not reached (NR) in the CDX-2 positive group versus 2.07 months (95%CI 2.07–10.8) in CDX-2 negative patients (p = 0.0011). Median OS was NR in CDX-2-positive patients versus 2.17 months (95% Confidence Interval [CI] 2.17–18.7) in CDX2-negative patients (p = 0.026). All CDX-2-positive patients achieved a disease response, one of them a complete response. Among CDX-2-negative patients, one achieved stable disease, while the other progressed rapidly (ORR: 100% vs 0%, p = 0.0005; DCR: 100% vs 50%, p = 0.02). Twelve patients received 1st-line pembrolizumab (11 CDX-2 positive and 1 CDX-2 negative) not reaching median PFS, while two patients (1 CDX-2 positive and 1 CDX-2 negative) received 3rd-line pembrolizumab reaching a median PFS of 10.8 months (95% CI, 10.8–12.1; p = 0.036). Although our study reports results on a small population, the prognostic role of CDX-2 in CRC seems confirmed and could drive a promising predictive role in defining the population more sensitive to immunotherapy treatment. Modulating the CDX-2/CXCL14 axis in CDX-2-negative patients could help overcome primary resistance to immunotherapy.
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- 2023
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13. Clinical score for colorectal cancer patients with lung-limited metastases undergoing surgical resection: Meta-Lung Score
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Ziranu, Pina, Ferrari, Paolo Albino, Guerrera, Francesco, Bertoglio, Pietro, Tamburrini, Alessandro, Pretta, Andrea, Lyberis, Paraskevas, Grimaldi, Giulia, Lai, Eleonora, Santoru, Massimiliano, Bardanzellu, Fabio, Riva, Laura, Balconi, Francesca, Della Beffa, Eleonora, Dubois, Marco, Pinna-Susnik, Matteo, Donisi, Clelia, Capozzi, Enrico, Pusceddu, Valeria, Murenu, Alessandro, Puzzoni, Marco, Mathieu, Federico, Sarais, Sabrina, Alzetani, Aiman, Luzzi, Luca, Solli, Piergiorgio, Paladini, Piero, Ruffini, Enrico, Cherchi, Roberto, and Scartozzi, Mario
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- 2023
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14. Prognostic Value of Body Mass Index in Stage II/III Colon Cancer: Posthoc Analysis From the TOSCA Trial
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Basile, Debora, Rosati, Gerardo, Bergamo, Francesca, Garattini, Silvio Ken, Banzi, Maria, Zampino, Maria, Bozzarelli, Silvia, Marchetti, Paolo, Galli, Fabio, Galli, Francesca, Longarini, Raffaella, Zaniboni, Alberto, Ferrari, Daris, De Placido, Sabino, Frassineti, Luca Giovanni, Nicolini, Mario, Cinieri, Saverio, Priscindiaro, Michele, Ziranu, Pina, Caccialanza, Riccardo, Pastorino, Alessandro, Mosconi, Stefania, and Aprile, Giuseppe
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- 2023
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15. Clustered protocadherins methylation alterations in cancer
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Vega-Benedetti, Ana Florencia, Loi, Eleonora, Moi, Loredana, Blois, Sylvain, Fadda, Antonio, Antonelli, Manila, Arcella, Antonella, Badiali, Manuela, Giangaspero, Felice, Morra, Isabella, Columbano, Amedeo, Restivo, Angelo, Zorcolo, Luigi, Gismondi, Viviana, Varesco, Liliana, Bellomo, Sara Erika, Giordano, Silvia, Canale, Matteo, Casadei-Gardini, Andrea, Faloppi, Luca, Puzzoni, Marco, Scartozzi, Mario, Ziranu, Pina, Cabras, Giuseppina, Cocco, Pierluigi, Ennas, Maria Grazia, Satta, Giannina, Zucca, Mariagrazia, Canzio, Daniele, and Zavattari, Patrizia
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Biological Sciences ,Genetics ,Cancer ,Colo-Rectal Cancer ,Digestive Diseases ,Rare Diseases ,Human Genome ,2.1 Biological and endogenous factors ,Aetiology ,Cadherins ,CpG Islands ,DNA Methylation ,Epigenesis ,Genetic ,Gene Expression Regulation ,Neoplastic ,High-Throughput Nucleotide Sequencing ,Humans ,Multigene Family ,Neoplasms ,Promoter Regions ,Genetic ,Sequence Analysis ,DNA ,Clustered PCDH ,Cancer methylation alteration ,CpG islands ,CTCF ,Low grade glioma ,LGG ,Pilocytic astrocytoma ,PA ,Colorectal carcinoma ,CRC ,Colorectal adenoma ,CRA ,Gastric cancer ,GC ,Biliary tract cancer ,BTC ,Chronic lymphocytic leukemia ,CLL ,Clinical Sciences ,Paediatrics and Reproductive Medicine - Abstract
BackgroundClustered protocadherins (PCDHs) map in tandem at human chromosome 5q31 and comprise three multi-genes clusters: α-, β- and γ-PCDH. The expression of this cluster consists of a complex mechanism involving DNA hub formation through DNA-CCTC binding factor (CTCF) interaction. Methylation alterations can affect this interaction, leading to transcriptional dysregulation. In cancer, clustered PCDHs undergo a mechanism of long-range epigenetic silencing by hypermethylation.ResultsIn this study, we detected frequent methylation alterations at CpG islands associated to these clustered PCDHs in all the solid tumours analysed (colorectal, gastric and biliary tract cancers, pilocytic astrocytoma), but not hematologic neoplasms such as chronic lymphocytic leukemia. Importantly, several altered CpG islands were associated with CTCF binding sites. Interestingly, our analysis revealed a hypomethylation event in pilocytic astrocytoma, suggesting that in neuronal tissue, where PCDHs are highly expressed, these genes become hypomethylated in this type of cancer. On the other hand, in tissues where PCDHs are lowly expressed, these CpG islands are targeted by DNA methylation. In fact, PCDH-associated CpG islands resulted hypermethylated in gastrointestinal tumours.ConclusionsOur study highlighted a strong alteration of the clustered PCDHs methylation pattern in the analysed solid cancers and suggested these methylation aberrations in the CpG islands associated with PCDH genes as powerful diagnostic biomarkers.
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- 2019
16. Guideline Application in Real world: multi-Institutional Based survey of Adjuvant and first-Line pancreatic Ductal adenocarcinoma treatment in Italy. Primary analysis of the GARIBALDI survey
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Reni, Michele, Macchini, Marina, Orsi, Giulia, Peretti, Umberto, Valente, Mariamaddalena, Giommoni, Elisa, Antonuzzo, Lorenzo, Di Costanzo, Francesco, Bergamo, Francesca, Zagonel, Vittorina, Lonardi, Sara, Buggin, Federica, Milella, Michele, Palmerio, Silvia, Cavanna, Luigi, Di Nunzio, Camilla, Di Marco, Maria Cristina, Grassi, Elisa, Spada, Massimiliano, Messina, Marco, Cordio, Stefano, Avola, Francesco, Aprile, Giuseppe, Pagano, Salvatore, Simionato, Francesca, Cardellino, Giovanni Gerardo, Majer, Federica, Maiello, Evaristo, Latiano, Tiziana Pia, Chiarazzo, Cinzia, Artioli, Fabrizio, Razzini, Giorgia, Pasqualini, Antonella, Ghidini, Michele, Binda, Elisa, Lazzarelli, Silvia, Bozzarelli, Silvia, Sala, Simona, Luppi, Gabriele, Pettorelli, Elisa, Spallanzani, Andrea, Vicario, Giovanni, Salmaso, Flavia, Basso, Marco, Silvestris, Nicola, Del Curatolo, Sabina, Zustovich, Fable, Bongiovanni, Francesca, Longobardi, Ciro, Sandi, Ilenia, Fontanella, Caterina, Montelatici, Silvia, Giordano, Monica, Luchena, Giovanna, Gilardoni, Micol, Tamburini, Emiliano, Rudnas, Britt, Venturini, Barbara, Merelli, Barbara, Negrini, Giorgia, Vici, Elio Maria, Marabese, Alessandra, Garetto, Cristina, Curcio, Paola, Cinieri, Saverio, Cinefra, Margherita, Ferrara, Pasqualinda, Cantore, Maurizio, Morselli, Patrizia, Fumi, Guglielmo, Isidori, Agnese, Ciccarese, Giovanni, Paolo Frassineti, Giovanni Luca, Pagan, Flavia, Vaccaro, Vanja, Spoto, Chiara, Ferrara, Marianna, Garufi, Carlo, Caporale, Marta, Vasile, Enrico, Salani, Francesca, Barone, Elisa, Berardi, Rossana, Onofri, Azzurra, Ballatore, Zelmira, Lucarelli, Alessandra, Barucca, Alessandra, Pancotti, Amedeo, Scipioni, Teresa, Bencardino, Katia, Marrapese, Giovanna, Idotta, Laura, Petrelli, Fausto, Lonati, Veronica, Ceribelli, Anna, Giuli, Angelo, Zannori, Cristina, Bassanelli, Maria, Mambrini, Andrea, Ginocchi, Laura, Orlandi, Massimo, Celio, Luigi, Niger, Monica, Biamonte, Lavinia, Tamberi, Stefano, Piancastelli, Alessandra, Papiani, Giorgio, Valli, Irene, Allione, Paolo, Boe, Maria Giovanna, Scartozzi, Mario, Lai, Eleonora, Pireddu, Annagrazia, Ziranu, Pina, Demurtas, Laura, Puzzoni, Marco, Mariani, Stefano, Pretta, Andrea, Liscia, Nicole, Savastano, Clementina, Malaspina, Valentina, Tonini, Giuseppe, Grassani, Teresa, Barco, Barbara, Pierosandro, Tagliaferri, Ciliberto, Domenico, Ierardi, Antonella, Calandruccio, Natale Daniele, Minotti, Vincenzo, Matocci, Roberta, Torri, Valter, Porcu, Luca, Rulli, Erica, De Simone, Irene, Carlucci, Luciano, Rulli, Eliana, Poli, Davide, Tonto, Paola, Scellato, Francesca, Pinto, Carmine, Reni, M., Giommoni, E., Bergamo, F., Milella, M., Cavanna, L., Di Marco, M.C., Spada, M., Cordio, S., Aprile, G., Cardellino, G.G., Maiello, E., Bernardini, I., Ghidini, M., Bozzarelli, S., Macchini, M., Orsi, G., De Simone, I., Rulli, Er., Porcu, L., Torri, V., and Pinto, C.
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- 2023
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17. Cemented vs uncemented megaprostheses in proximal femur metastases: a multicentric comparative study
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Maria Serena Oliva, Francesco Muratori, Raffaele Vitiello, Antonio Ziranu, Lorenzo Foschi, Giuseppe Rovere, Cesare Meschini, Domenico Andrea Campanacci, and Giulio Maccauro
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Metastases ,Proximal femur ,Megaprostheses ,Diseases of the musculoskeletal system ,RC925-935 - Abstract
Abstract Background Hip megaprostheses are a long known reconstructive method in the treatment of proximal femur metastases. The use of cemented or uncemented stems is still matter of debate. The aim of this study to compare cemented and uncemented megaprostheses on functional outcomes and complications, in order to establish the role of cementation. Methods We retrospectively analysed 51 metastatic patients with proximal femur metastases treated with endoprosthetic reconstruction by megaprostheses, 25 with cementless stems and 26 with cemented ones with different megaprosthetic implants. The primary endpoint was MSTS score, and the secondary endpoint was to state the incidence of surgical and clinical complications in the two groups. An un-paired T test was used to compare anthropometric, anamnestic data, and MSTS. Chi-square test was performed for evaluation of complication in the two group. Multiple linear regression was used to match the functional outcomes and complications’ incidence in the population study. Logistic regression was performed to analyse the odds ratio of different parameters and their role in the incidence of complications. Results The mean follow-up was 50.1 months (+ 12.5). In thirty case right side was involved. No statistical differences were noticed between Group A and B regard the age, gender, active fracture/impending fracture. Comparing the MSTS results within the two groups at last follow-up, the score cemented group was higher than cementless one (17.9 + 7.8 vs 24.2 + 5.3; statistical significance p = 0.001). Regarding surgical complications a logistic regression was performed to analyse the odds ratio of age, cementation and length of resection; cementation confirm and odds ratio of 11 times in the incidence of surgical complications. Conclusions Cementation seems to be more liable to complications onset, while improves functional score in metastatic patients compared to uncemented megaprostheses. More studies have to be conducted in order to create a protocol and establish criteria to use cemented or uncemented stems in a frail population like metastatic patients.
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- 2022
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18. A new prognostic tool for metastatic colorectal cancer patients receiving anti-angiogenic treatment, the PALM score: A single-center experience.
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Lai, Eleonora, primary, Palmas, Enrico, additional, Loi, Francesco, additional, Ziranu, Pina, additional, Mariani, Stefano, additional, Pretta, Andrea, additional, D'Agata, Alessandra Pia, additional, Dell'Utri, Veronica, additional, Papalexis, Giulia, additional, Deias, Giulia, additional, Rizzo, Daiana, additional, Spanu, Dario, additional, Sanna, Giorgia, additional, Moledda, Giusy, additional, Cadoni, Andrea, additional, Cucca, Mattia, additional, Donisi, Clelia, additional, Pusceddu, Valeria, additional, Puzzoni, Marco, additional, and Scartozzi, Mario, additional
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- 2024
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19. HOXD8 hypermethylation as a fully sensitive and specific biomarker for biliary tract cancer detectable in tissue and bile samples
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Loi, Eleonora, Zavattari, Cesare, Tommasi, Alessandro, Moi, Loredana, Canale, Matteo, Po, Agnese, Sabato, Claudia, Vega-Benedetti, Ana Florencia, Ziranu, Pina, Puzzoni, Marco, Lai, Eleonora, Faloppi, Luca, Rullán, María, Carrascosa, Juan, Amat, Irene, Urman, Jesús M., Arechederra, Maria, Berasain, Carmen, Ferretti, Elisabetta, Casadei-Gardini, Andrea, Avila, Matías A., Alonso, Sergio, Scartozzi, Mario, and Zavattari, Patrizia
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- 2022
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20. Three-Dimension-Printed Custom-Made Prosthetic Reconstructions in Bone Tumors: A Single Center Experience
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Raffaele Vitiello, Maria Rosaria Matrangolo, Alessandro El Motassime, Andrea Perna, Luigi Cianni, Giulio Maccauro, and Antonio Ziranu
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bone tumors ,computer-aided design ,3D-printed prosthesis ,reconstruction surgery ,custom-made prosthesis ,large bone defects ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Bone can be affected by different neoplastic conditions. Limb salvage surgery has become the preferred treatment strategy for most malignant tumors of the extremities. Advanced 3D printing technology has transformed the conventional view of oncological surgery. These types of implants are produced by electron beam melting (EBM) technology by sintering titanium powder in a scaffold shape designed following a project designed from HRCT and MRI. The aim of our study was to evaluate the outcomes and the mid-term follow-up of a population treated with 3D-printed custom-made prosthesis implantation in major oncological bone resection or after failure of primary implants. The primary outcome was the general patient satisfaction one year after surgery. The secondary outcomes were: mortality rate, treatment related complication rate, functional and clinical outcomes (KPS, ADL and IADL). Eight patients were included, five females and two males, with a mean age of 50.3 (±23.72) years at the surgery. The enrolled patients reported a mean satisfaction rate after surgery of 7.38 (±2) where 10 was the maximum value. There were no changes between pre- and postoperative mean KPS (81.43 +/−10.69). Mean preoperative ADL and IADL score was in both cases 4.86 (±1.07), while postoperative was 5 (±0.82), with a delta of 0.13 (p > 0.05). Custom-made prosthesis permits reconstructing bone defects caused by large tumor resection, especially in anatomically complex areas, restoring articular function.
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- 2022
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21. The role of immune checkpoint inhibitors in the treatment sequence of advanced gastric or gastro-esophageal junction cancer: A systematic review and meta-analysis of randomized trials
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Dubois, Marco, Liscia, Nicole, Brunetti, Oronzo, Ziranu, Pina, Lai, Eleonora, Argentiero, Antonella, Mazza, Elena, Cascinu, Stefano, Silvestris, Nicola, Casadei-Gardini, Andrea, and Scartozzi, Mario
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- 2022
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22. Colorectal cancer promoter methylation alteration affects the expression of glutamate ionotropic receptor AMPA type subunit 4 alternative isoforms potentially relevant in colon tissue
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Vega-Benedetti, Ana Florencia, Loi, Eleonora, Moi, Loredana, Restivo, Angelo, Cabras, Francesco, Deidda, Simona, Pretta, Andrea, Ziranu, Pina, Orrù, Sandra, Scartozzi, Mario, Zorcolo, Luigi, and Zavattari, Patrizia
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- 2022
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23. Femoral neck fracture: the reliability of radiologic classifications
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Gianpiero Cazzato, Maria Serena Oliva, Giulia Masci, Raffaele Vitiello, Alessandro Smimmo, Maria Rosaria Matrangolo, Osvaldo Palmacci, Stefano D’Adamio, and Antonio Ziranu
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Hip fractures ,Femoral neck fracture ,Femoral fractures’ classification ,Reliability ,Diseases of the musculoskeletal system ,RC925-935 - Abstract
Abstract Background Femoral neck fractures (FNF) are one of the most common injury in the elderly. A valid radiographic classification system is mandatory to perform the correct treatment and to allow surgeons to facilitate communication. This study aims to evaluate reliability of 2018 AO/OTA Classification, AO/OTA simplified and Garden classification. Methods Six Orthopaedic surgeons, divided in three groups based on trauma experience, evaluated 150 blinded antero-posterior and latero-lateral radiography of FNF using Garden classification, 2018 AO/OTA and simplified AO/OTA classification. One month later, the radiographs were renumbered and then each observer performed a second evaluation of the radiographs. The Kappa statistical analysis was used to determine the reliability of the classifications. Cohen’s Kappa was calculated to determine intra and inter observer reliability. Fleiss’ Kappa was used to determine multi-rater agreement. Results The k values of interobserver reliability for Garden classification was from 0,28 to 0,73 with an average of 0,49. AO classification showed reliability from 0,2 to 0,42, with average of 0,30. Simplified AO/OTA classification showed a reliability from 0,38 to 0,58 with an average of 0,48. The values of intra observer reliability for Garden classification was from 0,48 to 0,79 with an average of 0,63. AO classification showed reliability from 0,2 to 0,64 with an average of 0,5. Simplified AO/OTA classification showed a reliability from 0,4 to 0,75 with an average of 0,61. Conclusion The revised 2018 AO/OTA classification simplified the previous classification of intracapsular fracture but remain unreliable with only fair interobserver reliability. The simplified AO/OTA classification show a reliability similar to Garden classification, with a moderate interobserver reliability. The experience of the surgeons seems not to improve reliability. No classification has been shown to be superior in terms of reliability.
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- 2022
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24. Use of muscular flaps for the treatment of hip prosthetic joint infection: a systematic review
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Giuseppe Rovere, Domenico De Mauro, Marco D’Orio, Camillo Fulchignoni, Maria Rosaria Matrangolo, Carlo Perisano, Antonio Ziranu, and Elisabetta Pataia
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Arthroplasty ,Hip replacement ,Joint infection ,Hip prosthesis ,Muscular flaps ,Diseases of the musculoskeletal system ,RC925-935 - Abstract
Abstract Background Deep periprosthetic infection after total hip arthroplasty (THA) is a serious and challenging complication for the orthopedic surgeon. Muscular flaps may represent a valid management option for the treatment of this condition. We present a systematic literature review about the use of muscular flaps for the treatment of hip prosthetic joint infection. Methods The review is reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Seventy-seven articles, out of 279 titles, were considered eligible for the full-text analysis. Finally 15 studies that met inclusion criteria were included in this review. Results Overall, 210 patients (49% males, 48.6% females and 2.4% not reported) suffering from THA infection treated with muscular flaps were collected. The mean age was 69.6 years. Mean follow-up, reported in all studies, was 3.3 years. The results presented by the different authors, highlight the effectiveness of muscular flaps for the treatment of periprosthetic infection, in terms of function, limb salvage, prevention of the recurrences, cost-effectiveness, and quality of life postoperatively. Conclusions Muscle flaps provide an excellent management option for patients with persistent infection after total hip arthroplasty.
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- 2021
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25. Long Term Survival With Regorafenib: REALITY (Real Life in Italy) Trial - A GISCAD Study
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Lai, Eleonora, Puzzoni, Marco, Ziranu, Pina, Cremolini, Chiara, Lonardi, Sara, Banzi, Maria, Mariani, Stefano, Liscia, Nicole, Cinieri, Saverio, Dettori, Manuela, Mencoboni, Manlio, Nappo, Floriana, Piacentini, Giulia, Labianca, Roberto, Zucchelli, Gemma, Boccaccino, Alessandra, Conca, Veronica, Pusceddu, Valeria, Zaniboni, Alberto, and Scartozzi, Mario
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- 2021
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26. Recent Advances in the Surgical Management of Radiation-Induced Fractures following Soft Tissue Sarcomas
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Salvini, Matteo, primary, El Motassime, Alessandro, additional, Cavola, Francesco, additional, Ruberto, Pasquale, additional, Ziranu, Antonio, additional, and Maccauro, Giulio, additional
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- 2024
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27. Systemic Inflammation Response Index (SIRI) and Monocyte-to-Lymphocyte Ratio (MLR) Are Predictors of Good Outcomes in Surgical Treatment of Periprosthetic Joint Infections of Lower Limbs: A Single-Center Retrospective Analysis
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Vitiello, Raffaele, primary, Smimmo, Alessandro, additional, Matteini, Elena, additional, Micheli, Giulia, additional, Fantoni, Massimo, additional, Ziranu, Antonio, additional, Maccauro, Giulio, additional, and Taccari, Francesco, additional
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- 2024
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28. Prediction of Response to Anti-Angiogenic Treatment for Advanced Colorectal Cancer Patients: From Biological Factors to Functional Imaging
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Corrias, Giuseppe, primary, Lai, Eleonora, additional, Ziranu, Pina, additional, Mariani, Stefano, additional, Donisi, Clelia, additional, Liscia, Nicole, additional, Saba, Giorgio, additional, Pretta, Andrea, additional, Persano, Mara, additional, Fanni, Daniela, additional, Spanu, Dario, additional, Balconi, Francesca, additional, Loi, Francesco, additional, Deidda, Simona, additional, Restivo, Angelo, additional, Pusceddu, Valeria, additional, Puzzoni, Marco, additional, Solinas, Cinzia, additional, Massa, Elena, additional, Madeddu, Clelia, additional, Gerosa, Clara, additional, Zorcolo, Luigi, additional, Faa, Gavino, additional, Saba, Luca, additional, and Scartozzi, Mario, additional
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- 2024
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29. Effect of COVID-19 pandemic lockdowns on planned cancer surgery for 15 tumour types in 61 countries: an international, prospective, cohort study
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Glasbey, James, Ademuyiwa, Adesoji, Adisa, Adewale, AlAmeer, Ehab, Arnaud, Alexis P, Ayasra, Faris, Azevedo, José, Minaya-Bravo, Ana, Costas-Chavarri, Ainhoa, Edwards, John, Elhadi, Muhammed, Fiore, Marco, Fotopoulou, Christina, Gallo, Gaetano, Ghosh, Dhruva, Griffiths, Ewen A, Harrison, Ewen, Hutchinson, Peter, Lawani, Ismail, Lawday, Samuel, Lederhuber, Hans, Leventoglu, Sezai, Li, Elizabeth, Gomes, Gustavo Mendonça Ataíde, Mann, Harvinder, Marson, Ella J, Martin, Janet, Mazingi, Dennis, McLean, Kenneth, Modolo, Maria, Moore, Rachel, Morton, Dion, Ntirenganya, Faustin, Pata, Francesco, Picciochi, Maria, Pockney, Peter, Ramos-De la Medina, Antonio, Roberts, Keith, Roslani, April Camilla, Kottayasamy Seenivasagam, Rajkumar, Shaw, Richard, Simões, Joana Filipa Ferreira, Smart, Neil, Stewart, Grant D, Sullivan, Richard, Sundar, Sudha, Tabiri, Stephen, Taylor, Elliott H, Vidya, Raghavan, Nepogodiev, Dmitri, Bhangu, Aneel, Glasbey, James C, Bhangu, Aneel A, Siaw-Acheampong, Kwabena, Benson, Ruth A, Bywater, Edward, Chaudhry, Daoud, Dawson, Brett E, Evans, Jonathan P, Gujjuri, Rohan R, Heritage, Emily, Jones, Conor S, Kamarajah, Sivesh K, Khatri, Chetan, Khaw, Rachel A, Keatley, James M, Knight, Andrew, Mann, Harvinder S, McLean, Kenneth A, Mckay, Siobhan C, Mills, Emily C, Pellino, Gianluca, Tiwari, Abhinav, Simoes, Joana FF, Trout, Isobel M, Venn, Mary L, Wilkin, Richard JW, Smart, Neil J, Moug, Susan, Di Saverio, Salomone, Vallance, Abigail, Vimalchandran, Dale, Evans, Richard PT, Townend, Philip, McKay, Siobhan, Isaac, John, Satoi, Sohei, Coonar, Aman S, Marchbank, Adrian, Caruana, Edward J, Layton, Georgia R, Patel, Akshay, Brunelli, Alessandro, Ford, Samuel, Desai, Anant, Gronchi, Alessandro, Almond, Max, Tirotta, Fabio, Dumitra, Sinziana, Kolias, Angelos, Price, Stephen J, Fountain, Daniel M, Jenkinson, Michael D, Marcus, Hani J, Piper, Rory J, Lippa, Laura, Servadei, Franco, Esene, Ignatius, Freyschlag, Christian, Neville, Iuri, Rosseau, Gail, Schaller, Karl, Demetriades, Andreas K, Robertson, Faith, Alamri, Alex, Schache, Andrew G, Winter, Stuart C, Ho, Michael, Nankivell, Paul, Rey Biel, Juan, Batstone, Martin, Ganly, Ian, Wilkins, Alex, Singh, Jagdeep K, Thekinkattil, Dinesh, Leung, Elaine YL, Khan, Tabassum, Chiva, Luis, Sehouli, Jalid, Fagotti, Anna, Cohen, Paul, Gutelkin, Murat, Ghebre, Rahel, Konney, Thomas, Pareja, Rene, Bristow, Rob, Dowdy, Sean, Shylasree, TS, Ng, Joe, Fujiwara, Keiichi, Lamb, Benjamin, Narahari, Krishna, McNeill, Alan, Colquhoun, Alexandra, McGrath, John S, Bromage, Steve, Barod, Ravi, Kasivisvanathan, Veeru, Klatte, Tobias, Abbott, Tom EF, Abukhalaf, Sadi, Adamina, Michel, Ademuyiwa, Adesoji O, Agarwal, Arnav, Akkulak, Murat, Alameer, Ehab, Alderson, Derek, Alakaloko, Felix, Albertsmeier, Markus, Alser, Osaid, Alshaar, Muhammad, Alshryda, Sattar, Augestad, Knut Magne, Bankhead-Kendall, Brittany K, Barlow, Emma, Beard, David, Blanco-Colino, Ruth, Brar, Amanpreet, Breen, Kerry A, Bretherton, Chris, Buarque, Igor Lima, Burke, Joshua, Chaar, Mohammad, Chakrabortee, Sohini, Christensen, Peter, Cox, Daniel, Cukier, Moises, Cunha, Miguel F, Davidson, Giana H, Drake, Thomas M, Edwards, John G, Emile, Sameh, Farik, Shebani, Fitzgerald, J Edward, Garmanova, Tatiana, Grecinos, Gustavo, Gruendl, Magdalena, Halkias, Constantine, Harrison, Ewen M, Hisham, Intisar, Hutchinson, Peter J, Hwang, Shelley, Isik, Arda, Jonker, Pascal, Kaafarani, Haytham MA, Keller, Debby, Kruijff, Schelto, Litvin, Andrey, Loehrer, Andrew, Löffler, Markus W, Lorena, Maria Aguilera, Modolo, Maria Marta, Major, Piotr, Mashbari, Hassan N, Metallidis, Symeon, Mohan, Helen M, Moszkowicz, David, Ng-Kamstra, Joshua S, Maimbo, Mayaba, Negoi, Ionut, Niquen, Milagros, Olivos, Maricarmen, Oussama, Kacimi, Outani, Oumaima, Parreno-Sacdalanm, Marie Dione, Rivera, Carlos Jose Perez, Pinkney, Thomas D, van der Plas, Willemijn, Qureshi, Ahmad, Radenkovic, Dejan, Richards, Toby, Roslani, April C, Rutegård, Martin, Segura-Sampedro, Juan José, Santos, Irène, Sayyed, Raza, Schache, Andrew, Schnitzbauer, Andreas A, Seyi-Olajide, Justina O, Sharma, Neil, Shaw, Catherine A, Shu, Sebastian, Soreide, Kjetil, Spinelli, Antonino, Sund, Malin, Tsoulfas, Georgios, van Ramshorst, Gabrielle H, Vimalachandran, Dale, Warren, Oliver J, Wedderburn, Duane, Wright, Naomi, EuroSurg, Booth, Lesley, Runigamugabo, Emmy, Barker, Margaret, Barker, Neil, Cooke, Shirley, Doré, Suzanne, Horwood, Nigel, Tierney Weir, Carrie, Dajti, I, Allemand, C, Boccalatte, LA, Figari, M, Lamm, M, Larrañaga, J, Marchitelli, C, Noll, F, Odetto, D, Perrotta, M, Saadi, J, Zamora, L, Ballester, AM, Tapper, KE, Zeff, N, Valenzuela, JI, Alurralde, C, Anastasio, J, Apas Perez de Nucci, A, Caram, EL, Eskinazi, D, Mendoza, JP, Usandivaras, M, Badra, R, Esteban, A, García, JS, García, PM, Gerchunoff, JI, Lucchini, SM, NIgra, MA, Vargas, L, Hovhannisyan, T, Stepanyan, A, Vasey, CE, Watson, EGR, Ip, C, Kealey, J, Lim, CSH, Sengupta, S, Ward, S, Wong, E, Gould, T, Gourlay, R, Griffiths, B, Gananadha, S, McLaren, M, Cecire, J, Joshi, N, Salindera, S, Sutherland, A, Ahn, JH, Charlton, G, Chen, S, Gauri, N, Hayhurst, R, Jang, S, Jia, F, Mulligan, C, Yang, W, Ye, G, Zhang, H, Ballal, M, Gibson, D, Hayne, D, McMillan, H, Moss, J, Pugliese, MJ, Richards, T, Seow, YTN, Thian, A, Viswambaram, P, Vo, UG, Bennetts, J, Bright, T, Brooke-Smith, M, Fong, R, Gricks, B, Huang, L, Lam, YH, Nathan, A, Ong, BS, Ooi, E, Szpytma, M, Watson, D, Bagraith, K, Caird, S, Chan, E, Dawson, C, Ho, D, Hui, N, Izwan, S, Jeyarajan, E, Jordan, S, Liang, R, Lim, A, Nolan, GJ, Oar, A, Parker, D, Puhalla, H, Quennell, A, Rutherford, L, Sommerville, C, Townend, P, Von Papen, M, Wullschleger, M, Dawson, AC, Drane, A, Blatt, A, Cope, D, Egoroff, N, Fenton, M, Gani, J, Lott, N, Pockney, P, Shugg, N, Elliott, M, Phung, D, Phan, D, Townend, D, Bong, C, Gundara, J, Frankel, A, Bowman, S, Guerra, GR, Gerns, N, McGeorge, S, Riddell, A, Roberts, M, Rukin, N, Bolt, J, Buddingh, K, Dudi-Venkata, NN, Jog, S, Kroon, HM, Sammour, T, Smith, R, Stranz, C, Batstone, M, Lah, K, McGahan, W, Mitchell, D, Morton, A, Pearce, A, Sheahan, G, Swinson, B, Waldron, A, Walker, P, Alam, N, Banting, S, Chong, L, Choong, P, Clatworthy, S, Foley, D, Fox, A, Hii, MW, Knowles, B, Mack, J, Read, M, Rowcroft, A, Wright, G, Lun, EWY, Lanner, M, Burtscher, J, Trivik-Barrientos, F, Königsrainer, I, Bauer, M, Freyschlag, C, Kafka, M, Messner, F, Öfner, D, Tsibulak, I, Holawe, S, Zimmermann, M, Emmanuel, K, Grechenig, M, Gruber, R, Harald, M, Öhlberger, L, Presl, J, Wimmer, A, Namazov, I, Samadov, E, Barker, D, Boyce, R, Corbin, S, Doyle, A, Eastmond, A, Gill, R, Haynes, A, Millar, S, O'Shea, M, Padmore, G, Paquette, N, Phillips, E, St. John, S, Walkes, K, Abeloos, J, De Backer, T, De Ceulaer, J, Dick, C, Diez-Fraile, A, Lamoral, P, Spaas, C, Ceelen, W, Pattyn, P, Van de putte, D, Van Nieuwenhove, Y, Van Ramshorst, G, Willaert, W, Bazzett-Matabele, L, Chiyapo, SP, Ramogola-Masire, D, Ramontshonyana, G, Seiphetlheng, A, Vuylsteke, P, Abdallah, EA, Aguiar Júnior, S, Baiocchi, G, Carvalho, GB, Coimbra, FJF, Kowalski, LP, Makdissi, F, Marques, N, Marques, T, Soares Dos Santos, S, Tirapelli Gonçalves, B, Vartanian, JG, Dos Reis, R, Camara, P, De Lima, RK, Della Giustina, E, Hoffmann, PV, Gatti, A, Nardi, C, Oliva, R, Nacif, L, Carvalho Ferro, C, Gomes Mendonça Ataíde, G, Lima Buarque, I, Lira dos Santos Leite, A, Pol-Fachin, L, Santos Bezerra, T, Maylson Ramos da Silva, A, Windson de Araújo Silvestre, D, Vieira Barros, A, Campbell, L, De Cicco, R, Cecconello, I, Gregorio, P, Pontual Lima, L, Ribeiro Junior, U, Takeda, FR, Terra, RM, Faccini Teixeira, M, Kulcsar, MAV, Matos, LL, Nunes, KS, Laporte, G, Salem, M, Barakat Awada, J, Ijichi, TR, Kim, NJ, Marreiro, A, Muller, B, Nunes, R, Bodanese, B, Eidt, ER, Isoton, JC, Lemos Vieira da Cunha, M, Regina de Sampaio, L, Vendrame, C, Zeni, M, Zortéa, JA, Zortéa, MR, Sokolov, M, Kidane, B, Srinathan, S, Munro, A, Helyer, L, McKeen, D, Boutros, M, Caminsky, NG, Ghitulescu, G, Jamjoum, G, Moon, J, Pelletier, J, Vanounou, T, Wong, S, Cheng, D, MacNeil, SD, Martin, J, Dumitra, S, Kouyoumdjian, A, Schmid, S, Spicer, J, Agarwal, A, Brar, A, Dada, J, Dare, A, Hameed, U, Osman, F, Johnston, B, Russell, C, Groot, G, Persad, A, Pham, H, Wood, M, Ko, M, Rajendran, L, Demyttenaere, S, Garfinkle, R, Brown, C, Karimuddin, A, Lee, N, Liu, J, Madani Kia, T, Phang, PT, Raval, M, Tom, K, Abou-Khalil, J, Martel, A, Nessim, C, Stevenson, J, Al Riyami, S, Bali, K, Bigam, D, Dajani, K, Dell, A, Modolo, MM, Ramirez Nieto, P, Sepulveda, R, Molero, A, Bolbaran, A, Ruiz, I, Heredia, F, Bellolio, F, Besser, N, Grasset, E, Guaman, JO, Inzunza, M, Irarrázaval, MJ, Jarry, C, Quintana Martinic, M, Riquoir Altamirano, C, Romero Manqui, CA, Ruiz Esquide, M, Vargas Añazco, C, Almeciga, A, Fletcher, A, Merchan, A, Quijano, T, Sanabria, D, Arias-Amézquita, F, Cétares, C, Cortes Murgueitio, N, Gomez-Mayorga, JL, Herrera-Almario, G, Rodriguez, J, Iglesias, P, Puentes, LO, Calvache, JA, Orozco-Chamorro, CM, Rojas, DA, Sánchez-Gómez, A, Abadia, M, Acosta, J, Angel Aristizabal, J, Bonilla, A, Caicedo, L, Calderon Quiroz, PH, Cervera Bonilla, S, Diaz, S, Facundo, H, Garcia Mora, M, Guevara, O, Guzman, L, Herrera Mora, DR, Jimenez Ramirez, LJ, Lehmann, C, Manrique, E, Mariño, I, Medina, M, Pinilla Morales, RE, Puerto, A, Puerto Horta, J, Quintero, M, Rey Ferro, M, Saénz, A, Santana, D, Serrano, W, Suescun, O, Trujillo Sanchez, LM, Velasquez Cuasquen, BG, Mendoza Quevedo, J, Bacic, G, Karlovic, D, Kršul, D, Zelic, M, Luksic, I, Mamic, M, Bacic, I, Bakmaz, B, Coza, I, Dijan, E, Katusic, Z, Mihanovic, J, Morovic, D, Rakvin, I, Almezghwi, H, Arslan, K, Besim, H, Özant, A, Özçay, N, Frantzeskou, K, Gouvas, N, Kokkinos, G, Papatheodorou, P, Pozotou, I, Stavrinidou, O, Yiallourou, A, Martinek, L, Skrovina, M, Straka, M, Szubota, I, Peteja, M, Žatecký, J, Javurkova, V, Klat, J, Antony, S, Avlund, T, Berg, KD, Borre, M, Christensen, P, Elkjær, MC, Ernst, A, Fensman, SK, Haldrup, M, Harbjerg, JL, Iversen, LH, Jensen, PT, Jeppesen, TD, Kjaer, DW, Kristensen, HØ, Lund, N, Maigaard Axelsen, S, Mekhael, M, Mikic, N, Ostenfeld, EB, Ebbehøj, AL, Krarup, P, Schlesinger, N, Smith, H, Batista, S, Crespo, A, Díaz, PJ, Rivas, R, Rodriguez-Abreu, J, Tactuk, N, El Kassas, M, Omar, W, Tawheed, A, Talaat, M, Abdelsamed, A, Azzam, AY, Salem, H, Seleim, A, Abdelmajeed, A, Abdou, M, Abosamak, NE, AL Sayed, M, Ashoush, F, Atta, R, Elazzazy, E, Elnemr, M, Elsayed Hewalla, ME, Elsherbini, I, Essam, E, Ewedah, M, Ghallab, I, Hassan, E, Ibrahim, M, Metwalli, M, Mourad, M, Qatora, MS, Ragab, M, Sabry, A, Saifeldin, H, Samih, A, Samir Abdelaal, A, Shehata, S, Shenit, K, Attia, D, Kamal, N, Osman, N, Abbas, AM, Abd Elazeem, HAS, Abd-Elkariem, AY, Abdelkarem, MM, Alaa, S, Ashraf, M, Ayman, A, Azizeldine, MG, Elkhayat, H, Emad Mashhour, A, Gaber, M, Hamza, HM, Hawal, I, Hetta, HF, K. 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Tan, KHM, Vanker, R, Michel, M, Patil, S, Ravindran, S, Sarveswaran, J, Scott, L, Biliatis, I, Edmond, M, King, E, Babawale, O, Hodgson, D, Ismail, M, Khan, J, Lokman, U, Phan, YC, Almond, M, Bhangu, A, Breik, O, Cato, LD, Chowdhury, YA, Desai, A, Ford, S, Griffiths, E, Idle, M, Kamal, M, Karia, K, Kisiel, A, Kulkarni, R, Mak, JKC, Martin, T, Nankivell, P, Parente, A, Parmar, S, Pathanki, AM, Phelan, L, Praveen, P, Saeed, S, Sharma, N, Singh, J, Solomou, G, Soon, WC, Stevens, A, Tirotta, F, Topham, C, Ughratdar, I, Vijayan, D, Ballantyne, K, Barker, L, Chapman, K, Charalambous, M, Chianakwalam, C, English, C, Evans, J, Fell, A, Frimpong, D, Halkias, C, Iyer, R, Merh, R, Neagu, G, Nikolaou, S, Poddar, A, Pronisceva, V, Reddy, V, Williams, N, Alakandy, L, Bhattathiri, P, Brown, J, Canty, M, Day, E, Geddes, A, Grivas, A, Hassan, S, Lammy, S, Littlechild, P, Maseland, C, Mathieson, C, McCaul, J, McMahon, J, O'Kane, R, St. George, E, Suttner, N, Taylor, W, Tilling, E, English, W, Kaul, S, Khan, AH, Khan, F, Mansuri, A, Mukherjee, S, Sarigul, M, Tan, KL, Vulliamy, P, Woodham, A, Yang, YH, Adiamah, A, Brewer, H, Chowdhury, A, Humes, D, Jackman, J, Koh, A, Lewis-Lloyd, C, Navarro, A, Oyende, O, Reilly, J, Vohra, R, Worku, D, Cool, P, Cribb, G, Shepherd, K, Bisset, C, Moug, S, Chadha, R, Elson, N, Galleano, R, Faulkner, G, Langone, A, Panayi, Z, Saleh, P, Tuminello, F, Underwood, C, Brixton, G, Findlay, L, Klatte, T, Majkowska, A, Manson, J, Potter, R, Al-Khyatt, W, Bhalla, A, Chia, Z, Daliya, P, Goyal, A, Grimley, E, Hamad, A, Malcolm, FL, Ng, JCK, Phillips, A, Theophilidou, E, Williams, S, Bowden, J, Campain, N, Daniels, I, Fowler, G, John, J, Massey, L, McDermott, F, McGrath, J, McLennan, A, Ng, M, Pascoe, J, Rajaretnam, N, Angamuthu, N, Bulathsinhala, S, Chowdhury, S, Davidson, B, Fusai, G, Gilliland, J, Hart, C, Hidalgo Salinas, C, Knowles, J, Machairas, N, Mirnezami, R, Pissanou, T, Pollok, JM, Raptis, DA, Soggiu, F, Tzerbinis, H, Varcada, M, Xyda, S, Beamish, A, Davies, E, Foulkes, R, Magowan, D, Nassa, H, Ooi, R, Price, C, Smith, L, Solari, F, Tang, A, Williams, G, Abd Kahar, NN, Al-Tamimi, Y, Bacon, A, Beasley, N, Catto, J, Chan, LH, Chew, D, Crank, M, Ilenkovan, N, Macdonald, M, Narice, B, Rominiyi, O, Saad, S, Sinha, S, Thompson, A, Varley, I, Brennan, P, Drake, T, Harrison, EM, Linder, G, Mayes, J, McGregor, R, Pasricha, R, Skipworth, RJE, Zamvar, V, Hawkin, P, Raymond, T, Ryska, O, Baron, R, Dunne, D, Gahunia, S, Halloran, C, Howes, N, McKinney, R, McNicol, F, Rajput, K, Russ, J, Sutton, R, Szatmary, P, Tan, JR, Whelan, P, Anzak, A, Banerjee, A, Fuwa, O, Hughes, F, Jayasinghe, JD, Knowles, C, Kocher, HM, Leal Silva, I, Ledesma, FS, Minicozzi, A, Navaratne, L, Patki, P, Rahman, R, Ramamoorthy, R, Sohrabi, C, Tanabalan, C, Thaha, M, Thakur, B, Venn, M, Yip, V, Baumber, R, Parry, J, Evans, S, Jeys, L, Morris, G, Parry, M, Ahmadi, N, Aresu, G, Barrett-Brown, ZM, Coonar, A, Durio Yates, H, Gearon, D, Hogan, J, King, M, Peryt, A, Pradeep, IS, Adishesh, M, Atherton, R, Baxter, K, Brocklehurst, M, Chaudhury, M, Krishnamohan, N, McAleer, J, Owens, G, Parkin, E, Patkar, P, Phang, I, Aladeojebi, A, Ali, M, Barmayehvar, B, Gaunt, A, Gowda, M, Halliday, E, Kitchen, M, Mansour, F, Nanjaiah, P, Zakai, D, Abbassi-Ghadi, N, Assalaarachchi, H, Currie, A, Flavin, M, Frampton, A, Hague, M, Hammer, C, Hopper, J, Horsnell, J, Humphries, S, Kamocka, A, Madhuri, TK, Preston, S, Singh, P, Stebbing, J, Tailor, A, Walker, D, Coomber, E, Jaunoo, S, Kennedy, L, Airey, A, Bunni, J, Crowley, R, Fairhurst, K, Frost, J, George, R, Lee, S, Mitchell, S, Phull, J, Richards, S, Aljanadi, F, Campbell, A, Glass, A, Hraishawi, I, Jones, M, McIlmunn, C, McIntosh, S, Mhandu, P, O'Donnell, C, Turkington, R, Al-Ishaq, Z, Bhasin, S, Bodla, AS, Burahee, A, Crichton, A, El-Ghobashy, A, Fossett, R, Pigadas, N, Rahman, E, Snee, D, Vidya, R, Yassin, N, Fountain, D, Hasan, MT, Karabatsou, K, Laurente, R, Pathmanaban, O, Barlow, C, Ding, D, Foster, J, Longstaff, L, Brett-Miller, C, Buruiana, FE, Al-mukhtar, A, Edwards, J, Giblin, A, Kelty, C, Lee, M, Lye, G, Newman, T, Sharkey, A, Steele, C, Sureshkumar Shah, N, Whitehall, E, Blair, J, Lakhiani, A, Parry-Smith, W, Sahu, B, Athwal, R, Baker, A, Jones, L, Konstantinou, C, Ramcharan, S, Vatish, J, Wilkin, R, Alzetani, A, Amer, K, Badran, A, Colvin, HV, Ethunandan, M, Sekhon, GK, Shakoor, Z, Shields, H, Singh, R, Talbot, T, Wensley, F, Lawday, S, Lyons, A, Newman, S, Chung, E, Hagger, R, Hainsworth, A, Hunt, I, Karim, A, Owen, H, Ramwell, A, Santhirakumaran, G, Smelt, J, Tan, C, Vaughan, P, Williams, K, Baker, C, Davies, A, Gossage, J, Kelly, M, Knight, W, Bromage, S, Hall, J, Kaushik, V, Rudic, M, Vallabh, N, Zhang, Y, Harris, G, James, G, Kang, C, Lin, DJ, Rajgor, AD, Royle, T, Scurrah, R, Steel, B, Watson, LJ, Choi, D, Hutchison, R, Luoma, V, Marcus, HJ, May, R, Menon, A, Pramodana, B, Webber, L, Hayes, A, Jones, R, Sivarajah, G, Smith, M, Smrke, A, Strauss, D, Abouelela, FAM, Aneke, IA, Asaad, P, Brown, B, Collis, J, Duff, S, Khan, A, Moura, F, Taylor, M, Wadham, B, Warburton, H, Elmoslemany, T, Jenkinson, MD, Millward, CP, Zakaria, R, Mccluney, S, Parmar, C, Shah, S, Allison, J, Babar, MS, Bowen, J, Collard, B, Goodrum, S, Lau, K, Sargent, M, Scott, R, Thomas, E, Whitmore, H, Balasubramaniam, D, Jayasankar, B, Kapoor, S, Ramachandran, A, Semple, C, Elhamshary, A, Imam, SMB, Kapriniotis, K, Kasivisvanathan, V, Lindsay, J, Rakhshani-Moghadam, S, Beech, N, Chand, M, Green, L, Kalavrezos, N, Kiconco, H, McEwen, R, Schilling, C, Sinha, D, Pereca, J, Chopra, S, Egbeare, D, Thomas, R, Arumugam, S, Ibrahim, B, Khan, K, Combellack, T, Hill, G, Jones, S, Kornaszewska, M, Mohammed, M, Tahhan, G, Valtzoglou, V, Blencowe, N, Eskander, P, Gash, K, Gourbault, L, Hanna, M, Maccabe, TA, Main, B, Olivier, J, Newton, C, Roswadowski, S, Ryan, N, Teh, E, West, D, Al-omishy, H, Baig, M, Bates, H, Di Taranto, G, Dickson, K, Dunne, N, Gill, C, Howe, D, Jeevan, D, Khajuria, A, Martin-Ucar, A, McEvoy, K, Naredla, P, Robertson, S, Sait, M, Sarma, DR, Shanbhag, S, Shortland, T, Simmonds, S, Skillman, J, Tewari, N, Walton, G, Akhtar, MA, Brunt, A, McIntyre, J, Milne, K, Rashid, MM, Sgrò, A, Stewart, KE, Turnbull, A, Abou-Foul, AK, Gossedge, G, O'Donnell, S, Oldfield, F, Thomson, S, Aguilar Gonzalez, M, Talukder, S, Boyle, C, Fernando, D, Gallagher, K, Laird, A, Tham, D, Bath, M, Basnyat, P, Davis, H, Montauban, P, Shrestha, A, Agarwal, K, Arif, T, Magee, C, Nambirajan, T, Powell, S, Vinayagam, R, Flindall, I, Hanson, A, Mahendran, V, Green, S, Lim, M, MacDonald, L, Miu, V, Onos, L, Sheridan, K, Young, R, Alam, F, Griffiths, O, Houlden, C, Kolli, VS, Lala, AK, Leeson, S, Peevor, R, Seymour, Z, Consorti, E, Gonzalez, R, Grolman, R, Kwan-Feinberg, R, Liu, T, Merzlikin, O, Brown, A, Cooper, Z, Hirji, S, Jolissaint, J, Mahvi, D, Okafor, B, Raut, CP, Roxo, V, Salim, A, Bessen, S, Chen, L, Dagrosa, L, Fay, K, Fleischer, C, Hasson, R, Henderson, E, Leech, M, Loehrer, A, Markey, C, Paydarfar, J, Rosenkranz, K, Telma, K, Tocci, N, Wilkinson-Ryan, I, Bokenkamp, M, Brown, K, Fleming, D, Heron, C, Hill, C, Kay, H, Leede, E, McElhinney, K, Olson, KA, Osterberg, EC, Riley, C, Srikanth, P, Barbour, J, Blazer, D, DiLalla, GA, Fayanju, O, Hwang, ES, Kahmke, R, Kazaure, H, Lazarides, A, Lee, W, Lidsky, M, Menendez, C, Moris, D, Plichta, J, Pradhan, MC, Puscas, L, Rice, HE, Rocke, D, Rosenberger, L, Scheri, R, Smith, BD, Stang, MT, Tolnitch, L, Turnage, K, Visgauss, J, Walton, FS, Watts, T, Zani, S, Farma, J, Cardona, K, Russell, MC, Clark, J, Kwon, D, Goel, N, Kronenfeld, J, Bigelow, B, Etchill, E, Gabre-Kidan, A, Jenny, H, Kent, A, Ladd, MR, Long, C, Malapati, H, Margalit, A, Rapaport, S, Rose, J, Stevens, K, Tsai, L, Vervoort, D, Yesantharao, P, Dehal, A, Klaristenfeld, D, Huynh, K, Kaafarani, H, Naar, L, Qadan, M, Brown, L, Ganly, I, Mullinax, JE, Alpert, N, Gillezeau, C, Miles, DDS, Taioli, E, Cha, DE, Gleeson, E, Horn, C, Sarpel, U, Gusani, N, Hazelton, J, Maines, J, Oh, JS, Ssentongo, A, Ssentongo, P, Bhama, A, Colling, K, Najarian, M, Azam, M, Choudhry, A, Marx, W, Abedin, Y, Arzumanov, G, Chokshi, R, Gabrilovich, S, Glass, N, Kalyoussef, E, Parvin-Nejad, FP, Roden, D, Stein, J, Suarez-Ligon, A, Tsui, G, Zhao, K, Fleming, J, Fuson, A, Gigliotti, J, Ovaitt, A, Ying, Y, Abel, MK, Andaya, V, Bigay, K, Boeck, MA, Chern, H, Corvera, C, El-Sayed, I, Glencer, A, Ha, P, Hamilton, BCS, Heaton, C, Hirose, K, Jablons, DM, Kirkwood, KS, Kornblith, LZ, Kratz, JR, Lee, RH, Miller, PN, Nakakura, EK, Nunez-Garcia, B, O'Donnell, RJ, Ozgediz, D, Park, P, Robinson, B, Sarin, A, Sheu, B, Varma, MG, Wai, KC, Wustrack, R, Xu, MJ, Zimel, M, Beswick, D, Goddard, J, Manor, J, Song, J, Cioci, A, Pavlis, W, Rakoczy, K, Ruiz, G, Saberi, R, Fullmer, T, Gaskill, C, Gross, N, Kiong, K, Roland, CL, Zafar, SN, Abdallah, M, Abouassi, A, Aigbivbalu, E, Eid, J, George, B, Kulkarni, G, Marwan, H, Mehdi, M, San Andrés, M, Sundaresan, J, Aoun, SG, Ban, VS, Batjer, HH, Bosler, K, Caruso, J, Sumer, B, Abbott, D, Acher, A, Aiken, T, Barrett, J, Foley, E, Schwartz, PB, Hawkins, AT, Maiga, A, Ruzgar, NM, Sion, M, Ullrich, S, Laufer, J, Scasso, S, Al-Naggar, H, Al-Shehari, M, Almassaudi, A, Alsayadi, M, Alsayadi, R, Nahshal, M, Shream, S, AL-Ameri, S, and Aldawbali, M
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- 2021
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30. BRCA-mutant pancreatic ductal adenocarcinoma
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Lai, Eleonora, Ziranu, Pina, Spanu, Dario, Dubois, Marco, Pretta, Andrea, Tolu, Simona, Camera, Silvia, Liscia, Nicole, Mariani, Stefano, Persano, Mara, Migliari, Marco, Donisi, Clelia, Demurtas, Laura, Pusceddu, Valeria, Puzzoni, Marco, and Scartozzi, Mario
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- 2021
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31. The Role of p53 Expression in Patients with RAS/BRAF Wild-Type Metastatic Colorectal Cancer Receiving Irinotecan and Cetuximab as Later Line Treatment
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Ziranu, Pina, Lai, Eleonora, Schirripa, Marta, Puzzoni, Marco, Persano, Mara, Pretta, Andrea, Munari, Giada, Liscia, Nicole, Pusceddu, Valeria, Loupakis, Fotios, Demurtas, Laura, Libertini, Michela, Mariani, Stefano, Migliari, Marco, Dubois, Marco, Giampieri, Riccardo, Sotgiu, Giovanni, Dei Tos, Angelo Paolo, Lonardi, Sara, Zaniboni, Alberto, Fassan, Matteo, and Scartozzi, Mario
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- 2021
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32. Introducing immunotherapy for advanced hepatocellular carcinoma patients: Too early or too fast?
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Lai, Eleonora, Astara, Giorgio, Ziranu, Pina, Pretta, Andrea, Migliari, Marco, Dubois, Marco, Donisi, Clelia, Mariani, Stefano, Liscia, Nicole, Impera, Valentino, Persano, Mara, Tolu, Simona, Balconi, Francesca, Pinna, Giovanna, Spanu, Dario, Pireddu, Annagrazia, Saba, Giorgio, Camera, Silvia, Musio, Francesca, Puzzoni, Marco, Pusceddu, Valeria, Madeddu, Clelia, Casadei Gardini, Andrea, and Scartozzi, Mario
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- 2021
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33. Characteristics and Epidemiology of Megaprostheses Infections: A Systematic Review.
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Cianni, Luigi, Taccari, Francesco, Bocchi, Maria Beatrice, Micheli, Giulia, Sangiorgi, Flavio, Ziranu, Antonio, Fantoni, Massimo, Maccauro, Giulio, and Vitiello, Raffaele
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RISK assessment ,MEDICAL information storage & retrieval systems ,PROSTHESIS-related infections ,PATIENTS ,BONE tumors ,DESCRIPTIVE statistics ,CANCER patients ,EMERGENCY medical services ,ARTHROPLASTY ,SYSTEMATIC reviews ,MEDLINE ,LIMB salvage ,SOFT tissue tumors ,PLASTIC surgery ,ONLINE information services ,DISEASE risk factors - Abstract
Background: Megaprostheses were first employed in oncological orthopedic surgery, but more recently, additional applications have arisen. These implants are not without any risks and device failure is quite frequent. The most feared complication is undoubtedly the implants' infection; however, the exact incidence is still unknown. This systematic review aims to estimate in the current literature the overall incidence of megaprosthesis infections and to investigate possible risk/protective factors. Methods: We conducted a systematic search for studies published from July 1971 to December 2023 using specific keywords. To be included, studies needed to report either the megaprosthesis anatomical site, and/or whether the megaprosthesis was coated, and/or the surgical indication as oncological or non-oncological reasons. Results: The initial literature search resulted in 1281 studies. We evaluated 10,456 patients and the overall infection rate was 12%. In cancer patients, the infection rate was 22%, while in non-oncological patients, this was 16% (trauma 12%, mechanical failure 17%, prosthetic joint infections 26%). The overall infection rates comparing coated and uncoated implants were 10% and 12.5%, respectively. Conclusions: The number of megaprosthesis implants is increasing considerably. In traumatological patients, the infection rate is lower compared to all the other subgroups, while the infection rate remains higher in the cancer patient group. As these devices become more common, focused studies exploring epidemiological data, clinical outcomes, and long-term complications are needed to address the uncertainties in prevention and management. [ABSTRACT FROM AUTHOR]
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- 2024
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34. Liquid Biopsy-Driven Cetuximab Rechallenge Strategy in Molecularly Selected Metastatic Colorectal Cancer Patients
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Stefano Mariani, Marco Puzzoni, Riccardo Giampieri, Pina Ziranu, Valeria Pusceddu, Clelia Donisi, Mara Persano, Giovanna Pinna, Erika Cimbro, Alissa Parrino, Dario Spanu, Andrea Pretta, Eleonora Lai, Nicole Liscia, Alessio Lupi, Enrica Giglio, Grazia Palomba, Milena Casula, Marina Pisano, Giuseppe Palmieri, and Mario Scartozzi
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colorectal (colon) cancer ,epidermal growth factor receptor (EGFR) ,RAS ,liquid biopsy ,rechallenge ,cetuximab ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
BackgroundRechallenge with EGFR inhibitors represents a promising strategy for patients with RAS wild type (WT) colorectal cancer (CRC) but definitive selection criteria are lacking. Recently, the RAS WT status on circulating tumor DNA (ct-DNA) emerged as a potential watershed for this strategy. Our study explored the liquid biopsy-driven cetuximab rechallenge in a RAS and BRAF WT selected population.MethodsCRC patients with RAS and BRAF WT both on tumor tissue and on ct-DNA at baseline receiving rechallenge with cetuximab were eligible for our analysis. Ct-DNA was analyzed for RAS-BRAF mutations with pyro-sequencing and nucleotide sequencing assays. Real-time PCR and droplet digital PCR were performed to confirm the RAS-BRAF mutational status.ResultsA total of 26 patients were included in our analysis. In the global population, RR was 25.0%, median overall survival (mOS) was 5.0 months, and median progression-free survival (mPFS) was 3.5 months. Previous response to anti-EGFR was associated with improved mPFS (5.0 vs. 2.0 months, HR: 0.26, p = 0.048); anti-EGFR free interval > 14 months and anti-EGFR free interval > 16 months were associated with improved mPFS (respectively 7.0 vs. 3.0 months, HR: 0.27, p = 0.013 and not reached vs. 3.0 months, HR: 0.20, p = 0.002) and with improved mOS (respectively 13.0 vs. 5.0 months, HR: 0.27, p = 0.013 and 13.0 vs. 5.0 months, HR: 0.20, p = 0.002). Previous lines >2 were correlated with improved mPFS (4.0 vs. 1.0 month, HR: 0.05, p = 0.041) and with improved mOS (7.0 vs. 1.0 month, HR: 0.045, p = 0.034). In a multiple logistic regression model, only the anti-EGFR free interval was confirmed to be a significant predictor for mOS and mPFS.ConclusionsLiquid biopsy-driven cetuximab rechallenge was confirmed to be effective. The clinical outcome was consistent with available results from phase II studies. In addition to the molecular selection through the analysis of ct-DNA for RAS, the long anti-EGFR free interval is confirmed as a prospective selection criterion for this therapeutic option.
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- 2022
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35. Epidemiology and Treatment of Surgical Infection after Ankle Arthroscopy: A Systematic Review
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De Fazio, Andrea, primary, Bocchi, Maria Beatrice, additional, Miele, Guglielmo, additional, Ruberto, Pasquale, additional, Forconi, Fabrizio, additional, Ziranu, Antonio, additional, Maccauro, Giulio, additional, and Vitiello, Raffaele, additional
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- 2024
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36. Clinical and prognostic characteristics of early onset metastatic pancreatic cancer.
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Pretta, Andrea, primary, Giampieri, Riccardo, additional, Nichetti, Federico, additional, Ziranu, Pina, additional, Lupi, Alessio, additional, Cimbro, Erika, additional, Andena, Paola, additional, Felicetti, Cristiano, additional, Pircher, Chiara Carlotta, additional, Gusmaroli, Eleonora, additional, Donisi, Clelia, additional, Balconi, Francesca, additional, Mariani, Stefano, additional, Lai, Eleonora, additional, Puzzoni, Marco, additional, Pusceddu, Valeria, additional, Berardi, Rossana, additional, Niger, Monica, additional, and Scartozzi, Mario, additional
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- 2024
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37. Comparison between different therapeutic sequences in patients affected by metastatic pancreatic ductal adenocarcinoma.
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Pretta, Andrea, primary, Giampieri, Riccardo, additional, Nichetti, Federico, additional, Ziranu, Pina, additional, Lupi, Alessio, additional, Moledda, Giusy, additional, Andena, Paola, additional, Felicetti, Cristiano, additional, D'Agata, Alessandra Pia, additional, Pircher, Chiara Carlotta, additional, Codipietro, Claudia, additional, Rota, Simone, additional, Rizzo, Daiana, additional, Sanna, Giorgia, additional, Lai, Eleonora, additional, Puzzoni, Marco, additional, Pusceddu, Valeria, additional, Berardi, Rossana, additional, Niger, Monica, additional, and Scartozzi, Mario, additional
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- 2024
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38. Prognostic factors for anti-angiogenic treatment in patients with metastatic colorectal cancer: New insights for an old issue from a single institution experience.
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Lai, Eleonora, primary, Ziranu, Pina, additional, Mariani, Stefano, additional, Loi, Francesco, additional, Palmas, Enrico, additional, D'Agata, Alessandra Pia, additional, Dell'Utri, Veronica, additional, Deias, Giulia, additional, Balconi, Francesca, additional, Rizzo, Daiana, additional, Papalexis, Giulia, additional, Codipietro, Claudia, additional, Sanna, Giorgia, additional, Moledda, Giusy, additional, Donisi, Clelia, additional, Spanu, Dario, additional, Pretta, Andrea, additional, Pusceddu, Valeria, additional, Puzzoni, Marco, additional, and Scartozzi, Mario, additional
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- 2024
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39. Early onset metastatic colorectal cancer: Clinical-prognostic characteristics and correlation to molecular profile.
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Pretta, Andrea, primary, Ziranu, Pina, additional, Perissinotto, Eleonora, additional, Ciracì, Paolo, additional, Giuliani, Lorenzo, additional, Pusceddu, Valeria, additional, De Grandis, Maria Caterina, additional, Taravella, Ada, additional, Puzzoni, Marco, additional, Piva, Vittoria Matilde, additional, Boccaccio, Chiara, additional, Lai, Eleonora, additional, Prete, Alessandra Anna Anna, additional, Cerma, Krisida, additional, Marmorino, Federica, additional, Giampieri, Riccardo, additional, Lonardi, Sara, additional, Cremolini, Chiara, additional, Bergamo, Francesca, additional, and Scartozzi, Mario, additional
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- 2024
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40. Treatment of Scaphoid Non-Unions with Custom-Made 3D-Printed Titanium Partial and Total Scaphoid Prostheses and Scaphoid Interosseous Ligament Reconstruction
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Cioffi, Alessio, primary, Rovere, Giuseppe, additional, Bosco, Francesco, additional, Sinno, Ennio, additional, Stramazzo, Leonardo, additional, Liuzza, Francesco, additional, Ziranu, Antonio, additional, Romeo, Michele, additional, Vigni, Giulio Edoardo, additional, Galvano, Nicolò, additional, Maccauro, Giulio, additional, Farsetti, Pasquale, additional, Rossello, Mario Igor, additional, and Camarda, Lawrence, additional
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- 2023
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41. COVID-19 pandemic: management of patients affected by SARS-CoV-2 in Rome COVID Hospital 2 Trauma Centre and safety of our surgical team
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De Mauro, Domenico, Rovere, Giuseppe, Smimmo, Alessandro, Meschini, Cesare, Mocini, Fabrizio, Maccauro, Giulio, Falez, Francesco, Liuzza, Francesco, and Ziranu, Antonio
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- 2020
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42. Revision Surgery Using Retrograde Nail versus Replating in Nonunion Distal Femur Fracture Treated with Plate
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Antonio Ziranu, Giovanni Noia, Valerio Cipolloni, Michele Coviello, Giuseppe Maccagnano, Francesco Liuzza, Giulio Maccauro, Luigi Aurelio Nasto, and Enrico Pola
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Orthopedic surgery ,RD701-811 - Abstract
Articular distal femur fractures represent 4% to 6% of femur fractures. Locking compression plates (LCPs) are the main treatment option. Nevertheless, a reoperation rate of 12.9% has been reported; nonunion is reported at 4.8%, delayed union at 1.6%, and malunion at 0.6%. Treatment of nonunions can be challenging as no unanimous consensus regarding the best surgical technique has been reached. The aim of this study was to evaluate and compare two types of revision surgery as treatment of LCP-treated articular distal femoral fracture nonunion: retrograde nail or replating. A retrospective cohort study of patients admitted from January 2015 to February 2017 for nonunion of AO/OTA 33C2 fractures previously treated with a lateral LCP was conducted. Patients were treated either with intramedullary nailing (Group A) or with replating (Group B). One independent observer performed clinically and radiographically followed up at 1, 3, 6, 9, 12, 24, and 36 months after surgery. The nonunion scoring system (NUSS) was used. Nine patients were included in our study. The mean follow-up was 2 years. Five patients were treated with intramedullary nailing and four with replating. The NUSS score was 24.2 ± 6.8 in the nailing group and 37.3 ± 3 in the replating group (P=0.03). In the nailing group, radiographic consolidation was obtained in all cases. In the replating group, nonunion was found in 3 patients and failure of osteosynthesis in one patient. Therefore, four patients (Group B) underwent implant removal and retrograde femoral nailing, obtaining radiological healing. The union time was 7.6 months in the nailing group. Retrograde intramedullary nailing can be used as an effective treatment of aseptic AO-33C distal femoral nonunion following primary locking plating.
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- 2022
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43. Angiogenesis Genotyping and Clinical Outcomes in Patients with Advanced Hepatocellular Carcinoma Receiving Sorafenib: The ALICE-2 Study
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Faloppi, Luca, Puzzoni, Marco, Casadei Gardini, Andrea, Silvestris, Nicola, Masi, Gianluca, Marisi, Giorgia, Vivaldi, Caterina, Gadaleta, Cosmo Damiano, Ziranu, Pina, Bianconi, Maristella, Loretelli, Cristian, Demurtas, Laura, Lai, Eleonora, Giampieri, Riccardo, Galizia, Eva, Ulivi, Paola, Battelli, Nicola, Falcone, Alfredo, Cascinu, Stefano, and Scartozzi, Mario
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- 2020
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44. Retrospective Comparative Analysis of KRAS G12C vs. Other KRAS Mutations in mCRC Patients Treated With First-Line Chemotherapy Doublet + Bevacizumab
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Riccardo Giampieri, Alessio Lupi, Pina Ziranu, Alessandro Bittoni, Andrea Pretta, Federica Pecci, Mara Persano, Enrica Giglio, Cecilia Copparoni, Sonia Crocetti, Alessandra Mandolesi, Gavino Faa, Pierpaolo Coni, Mario Scartozzi, and Rossana Berardi
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mCRC ,KRAS ,G12C ,first line ,chemotherapy ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
BackgroundKRAS mutations in metastatic colorectal cancer (mCRC) define a subset of tumors that have primary resistance to anti-EGFR-based therapy. Data concerning whether different KRAS mutations may also have a prognostic value are lacking. Furthermore, novel KRAS G12C inhibitors are currently in development. The aim of our analysis was to compare response rates in patients treated with first-line chemotherapy doublet + Bevacizumab among different KRAS variants. Secondary end-points were progression free survival (PFS) and overall survival (OS).MethodsPatients with KRAS mutated mCRC treated with either FOLFIRI/FOLFOX/XELOX + Bevacizumab were eligible for enrollment. Patients whose tumor harbored NRAS mutations or that coexpressed also BRAF mutations were excluded from this retrospective analysis. Patients’ individual data were collected from patients’ records. Propensity score matching (nearest method, 1:2 ratio) was used to define the two different groups of patients for comparison (KRAS G12C mutated vs other KRAS variants). Eastern Cooperative Oncology Group Performance Status (ECOG PS), sex, metastatic site of involvement, synchronous vs metachronous metastatic disease, tumor sidedness, mucinous histology, primary tumor surgery, more than two lines of treatment for metastatic disease, and radical surgery of metastases were used as matching factors. Response rate (RR) was calculated by RECIST 1.1 criteria. Both progression free-survival and overall survival were calculated by Kaplan–Meier method. Categorical variables were compared by Fisher exact test for binomial variables and by chi-square test for all other instances. The level of statistical significance p was set at 0.05 for all tests.ResultsA total of 120 patients were assessed in the final analysis. Out of the 120 patients, 15 (12%) were KRAS G12C mutated. In the whole cohort of patients, 59/120 (49%) had partial response (PR), 42/120 (35%) had stable disease (SD), and 19/120 (16%) had progressive disease (PD) as the best response. In KRAS G12C patients, 4/15 (27%) had PR, 6/15 (40%) had SD, and the remaining 5/15 (33%) had PD as the best response. In patients with other KRAS mutations, 55/105 (52%) had PR, 37/105 (35%) had SD, and the remaining 13/105 (12%) had PD as the best response. The difference in RR between the two groups of patients was statistically significant (p=0.017). On the other hand, no difference in PFS (p=0.76) and OS (p=0.56) was observed. After matching procedures, the difference in response rates between KRAS G12C mutated patients vs the matched cohort of patients with other KRAS mutations remained statistically significant (p=0.016). KRAS G12C mutations were not associated with differences in sites of metastatic involvement, sex, and ECOG PS. On the other hand, synchronous vs metachronous metastatic disease (p=0.039), age > 75 years (p=0.043), and mucinous histology (p=0.008) were more frequent in G12C mutated tumors.ConclusionsIn our cohort of patients, it was observed that KRAS G12C mutations are associated with worse response rates compared to other KRAS variants when treated with standard chemotherapy doublet + Bevacizumab. On the other hand, both PFS and OS were not significantly different. Based on these findings, we believe that new treatment options focused on KRAS G12C inhibition should be tested mainly in first-line setting and in addition to standard chemotherapy doublet + Bevacizumab for mCRC patients, as they might “fill the gap” in response rates that was seen in our study.
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- 2021
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45. Cemented vs uncemented megaprostheses in proximal femur metastases: a multicentric comparative study
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Oliva, Maria Serena, Muratori, Francesco, Vitiello, Raffaele, Ziranu, Antonio, Foschi, Lorenzo, Rovere, Giuseppe, Meschini, Cesare, Campanacci, Domenico Andrea, and Maccauro, Giulio
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- 2021
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46. Femoral neck fracture: the reliability of radiologic classifications
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Cazzato, Gianpiero, Oliva, Maria Serena, Masci, Giulia, Vitiello, Raffaele, Smimmo, Alessandro, Matrangolo, Maria Rosaria, Palmacci, Osvaldo, D’Adamio, Stefano, and Ziranu, Antonio
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- 2021
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47. Use of muscular flaps for the treatment of hip prosthetic joint infection: a systematic review
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Rovere, Giuseppe, De Mauro, Domenico, D’Orio, Marco, Fulchignoni, Camillo, Matrangolo, Maria Rosaria, Perisano, Carlo, Ziranu, Antonio, and Pataia, Elisabetta
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- 2021
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48. Prognostic Value of Body Mass Index in Stage II/III Colon Cancer: Posthoc Analysis From the TOSCA Trial
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Debora Basile, Gerardo Rosati, Francesca Bergamo, Silvio Ken Garattini, Maria Banzi, Maria Zampino, Silvia Bozzarelli, Paolo Marchetti, Fabio Galli, Francesca Galli, Raffaella Longarini, Alberto Zaniboni, Daris Ferrari, Sabino De Placido, Luca Giovanni Frassineti, Mario Nicolini, Saverio Cinieri, Michele Priscindiaro, Pina Ziranu, Riccardo Caccialanza, Alessandro Pastorino, Stefania Mosconi, and Giuseppe Aprile
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Oncology ,Gastroenterology - Published
- 2023
49. A prognostic model for use before elective surgery to estimate the risk of postoperative pulmonary complications (GSU-Pulmonary Score): a development and validation study in three international cohorts
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Flumignan, Ronald, Slavchev, Mihail, Jaworska, Natalia, Dell, Angela, Shanthanna, Harsha, Martin, Janet, Behzadi, Abdollah, Nessim, Carolyn, Mozel, Michelle, St-germain, Pascal, Russell, Crispin, Groot, Gary, Safieddine, Najib, Wijeysundera, Duminda, Eskander, Antoine, Chadi, Sami, MacKenzie, Shawn, Heredia, Fernando, Villanueva, Julio, Waissbluth, Sofia, Macchiavello, Roberto, Escudero, Mario I, Fuentes, Tyare, Mimica, Ximena, Olivos, Maricarmen, Bolivar Saenz, Dinimo, Caicedo, Lina, Alzate, Juan Pablo, Luna, Joaquin, Pedraza Alonso, Nestor Fabian, Ortiz Silva, Camilo, Perez Rivera, Carlos J-, Rodriguez, Juliana, Silva-Igua, Liliana, Torres, Martha Luz, Trujillo, Lina María, Nieto Calvache, Albaro José, Balanta-Melo, Julián, Figueroa - Casanova, Rafael, García-Montoya, Oscar-Julián, Marulanda Toro, Carlos Andres, Mendoza Arango, Maria Clara, Diaz Martinez, Eneida, Gutiérrez Perdomo, Valentina, Calvache, Jose Andres, Montenegro, Emileth, Mihanovic, Jakov, Avilés Jiménez, Pablo Mijahil, 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Okunlola, Abiodun, Williams, Omolara, Adisa, Adewale, Abdur-Rahman, Lukman, Kache, Stephen, Sale, Danjuma, Anyanwu, Lofty-John, Okereke, Chukwuma, Tolani, Musliu Adetola, Filipce, Venko, Todorovic, Lazar, Pejkova, Sofija, Stavridis, Sotir, Massoud, John George, Alsibai, Sareyah, Sultan, Rizwan, Altaf, Humera Naz, Bhatti, Abu Bakar Hafeez, Waqar, Shahzad Hussain, Aziz, Aliya, Kerawala, Asad Ali, Rai, Lajpat, Anwer, Mariyah, Tariq, Aiman, Ayub, Bushra, Niazi, Sami ullah, Naseem, Muhammad Yasir, Sarwar, Muhammad Zeeshan, Khokhar, Muhammad Imran, Zahid, Imdad Ahmad, Majid, Haroon Javaid, Talat, Nabila, Asif, Muhammad, Chaudhary, Muhammad Hamid, Farooq, Umer, Ahmad, Siddique, Mabood, Waleed, Bukhari, Syed Imran, Tariq, Muhammad, Yaqoob, Eesha, Javed, Saad, Usman Malik, Muhammad, Yaqoob, Hassan Nawaz, Cukier, Moises, Falcon Pacheco, Glenda Marina, Mas Melendez, Robinson, Paucar Urbina, Arazzelly Del Pilar, Rios Chiuyari, Jose, Otiniano Alvarado, Carlos Eduardo, Fuentes Rivera Lau, Lorena, 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Emileth, Genda, Eben-ezer, Eboma, Fabrice, Grulović, Karlo, Bosak Versic, Ana, Srsen Medancic, Suzana, Brkic, Lucija, Cokarić, Sara, Tomić, Josipa, Brzic, Domagoj, Dijan, Emilio, Grgec Dragicevic, Maja, Konjevoda, Suzana, Morović, Domagoj, Perišić, Gordan, Zuzul, Matea, Anzic, Srdan Ante, Carevic, Iva, Biočina, Bojan, Bobovec, Dino, Bumber, Boris, Duric Vukovic, Katarina, Jelčić, Ivan, Kastelan, Zeljko, Kolak, Juraj, Pasini, Miram, Penezić, Luka, Prstacic, Ratko, Romić, Ivan, Tomic, Mislav, Luksic, Ivica, Avilés Jiménez, Pablo Mijahil, Panayiotou, Yiannis, Stavrinidou, Olga, Yiallourou, Anneza, Michal, Burda, Lukáš, Gawel, Wladyslaw B., Lerch, Milan, Macečková, Nicole, Simetka, Ondrej, Vavra, Petr, Zelenik, Karol, Přibyl, Martin, Klíma, Karel, Pirmorad, Setareh, Hotová, Zuzana, Mladěnka, Aleš, Bozo, Nulvin, Hviid, Louise, Kristensen, Helle Ø, Paulsen, Laerke, Ebbehøj, Anders Lyng, Jönsson, Maria Lovisa, Krarup, Peter-Martin, Otte, Helena, Smith, Henry, Bælum, Jens Kristian, Ellebæk, Signe Bremholm, Batista, Sylvia, Collado Expósito, María Mabel, Crespo, Aldo, D’óleo García, Claudio Samuel, Figueroa, Jatnna, Garcia-Dubus Rodriguez, U, Guzman, Lillian, Lopez, Ariela, Maletta Francisco, Leeany, Munoz, Herisardy, Perez Fernandez, Maricely Ambar, Rodríguez, Ada, Soto, Joel, Ubinas, Raul, Villegas, Aaron, Acra-Tolari, Ricardo, Beltran, Larissa, Betances, Luis Fernand, Díaz Vásquez, Pedro Pablo, Fernandez, Damaris, Figueroa Germosen, Jiomar Manuel, Mejia De la Cruz, Dolores, Ortiz De La Cruz, Fabio, Pelletier, Gabriela, Próspero Enrique, Rodriguez Pumarol, Suero Almanzar, Irina, Lincango-Naranjo, Eddy, Negrete Ocampo, José Ricardo, Sallam, Ibrahim, Sherief, Mohamed, Abdou, Mostafa, Abo Shanab, Ahmed, Abodeeb, Aya, Aboelkhel, Roger, Abosamak, Nour Eldin, Abouelnagah, Yossof, Adel, Dina, Ahmed, Sara, Alberkamy, Abdelrahman, Ali, Ahmed, Ashraf, Olfat, Darwish, Sara, El kharashy, Rasha, Elbadawy, Seifeldin, Elsaka, Alromisaa, Ewedah, Moataz, Ezz, Yara, Gadelrab, Ziyad, Hafez, Nour, Hafez, Youssef, Hassanin, Mohamed, Hussein Aly Salama Aly, Hamza, Ibrahim, Abdelrahman, Mahmoud Abo shabana, Alaa, Mourad, Mohamed, Mubarek, Kamilia, Omar, Samaa, Ragal, Marawan, Romany, John, Salem, Alaa, Samir Abdelaal, Ahmed, Shehata, Sameh, Shehata, Abdelrahman, Shenit, Karim, Yehia, Nermin, Khaled Mohamed Eid, Omar, Ibrahim Elsayed, Omar, Shehata, Mostafa Ahmed, Abd El-Ghani, Wael, Abd Elazeem, Hossam Aldein S., Abdalla, Shimaa, Abdel-Aleem, Mahmoud, Abdelfattah, Mahmoud, Abdelhafez, Mohammed, Abdelkarem, Mohamed M., Abubeih, Hossam, Ahmed, Nagm Eldin Abu Elnga, Ahmed, Ahmed, Ahmed Saad, Sarah, Ali, Abdelrahman Ahmed Abdelrahman, Elmaghraby, Khaled, Elsdfy, Shady, Eltayeb, Almoutaz, Essam, Esraa, Gadelkareem, Rabea, Ghoneim, Ahmed, Hamada Takrouney, Mohammed, Hasan, Ahmad, Hassanin, Mohamed Abdelghafor, Mahran, Wesam, Mahrous, Doha, Ragab, Abdelrahman, Sabry, Aya, Safwat, Hadeer, Saleh, Ahmed, Samir, Ahmed, Sayed, Esraa, Taher, Mohamed Gamal, Yousof, Ebrahim Ahmed, Youssef, Ahmed, Zein Elabedeen, Omar, Ali, Samar, Elbehairy, Gehad, Eleisawy, Mahmoud, Elgendy, Abdelrahman, Elhawary, Rewan, Hamdy, Mahmoud, Hassan, Gehad, Nowar, Mostafa, Sabry, Hesham, Tarek Said-elnaby, Ahmed, Zahed, Mohamed, Zahran, Mohamed, Zoghary, Ahmed Zaki, Atef, Mohamed, Abdelhamid, Mahmoud Hossameldin Saad, El Fiky, Lobna, ElGarhy, Ibrahim, Qassem, Mohamed, Wahba, Abdelrahman, Youssif Omar Fouad, Omar, Abdelsamed, Ahmed, Elsalhy, Mohamed, Eldesouky, Omnia, Wael Mostafa Khalil Bahi, Abdullah, Tawheed, Ahmed, Al-oribi, Saeid, Aly, Nuran Khaled, ElFiky, Mahmoud, Nabil, Ahmed, Samir Farahat, Ahmed, Soliman, Mostafa, Ghaly, Galal, Abbas, Alzhraa Salah, Ibraheem, Maher, Bakry, Abdelrahman, Jammal, Mohamed, M Makram, Abdelrahman, Adel abdelaty, Ahmed, Fayad, Elsayed A., Sallam, Moataz, Shehta, Ahmed, Elfeki, Hossam, Elsaid, Mahmoud, Mostafa, Mohamed, Sakr, Ahmed, Shetiwy, Mohamed, Tawakl, Noura, Yunes, Asmaa, Atallah, Khalid, Shetiwy, Mosab, Abdelmawla, Ahmed, Abdrabou, Ahmed, Abubakr, Asmaa, Al Gohary, Rawda, Elsabagh, Alaa, Elshabrawy, Enas, Hafez, Ahmed, Mikhail, Pola, Mohamed, Mervat, Nada, Ahmed, Omran, Janna, Salem, Osama, Selim, Salma, Shalaby, Ghada, Wahbah, Mahmoud, Zakaria Abdelbary, Eman, Zayan, Ahmad Helmy, Afify, Abdelrahman, Mohamed Ahmed, Mostafa, Abdeldayem, Hesham, Abdelkader Salama, Ibrahim, Ammar, Khaled, Ayoub, Islam, Gad, Emad Hamdy, Hammad, Essam, Macshut, Mahmoud, Sherif, Ahmed Elshawadfy, Shoreem, Hany, Soliman, Hossam Eldeen, Eldaly, Abdullah, Mashaly, Sarah, Abd-Elsalam, Sherief, Abdel-Elsalam, Wafaa, Morsy, Mohamed Sherif, Nasreddin, Mohammed, Sarsik, Sameh, Kams, Liisa, Rätsep, Tõnu, Riips, Karolin, Abebe, Kirubel, Asfaw, Fitsum, Eshete, Mahder, Gedefaw, Yetsedaw, Menjeta, Abeje, Muleta, Mahteme Bekele, Sefera, Sena, Teklu, Daniel, Tirfe, Leake, Worku, Bereket, Eado, Yegeremu, Negussie, Abraham, Woldemariam, Mersha Abebe, Alemu, Megersa, Azmach, Dawit, Mamo, Dr.Mickyas, Menkir, Abel, Woldemariam, Dereje, Wubishet, Estifanos, Supha, Melka, Abebe, Nebyou, Chanie, Abera, Gebre, Hiwot, Laeke, Tsegazeab, Mammo, Tihitena Negussie, Sahlu, Abat, Tiruneh, Abraham Genetu, Zewdneh, Betelhem, Fentaw, Jibril, Tabore, Ketema, Addisalem, Abreha, Tassew, Abdissa, Desalegn, Tesfaw, Mequannet, Asmamaw, Dawit, Bedane, Dereje, Bekele, Ephrem, Getie, Aderaw, Girma, Adissu, Shimelash, Dagim, Ayalew, Tewabe, Kassahun, Berhanu, Mulugeta, Esubalew, Sisay, Silamlak, Ibrahim, Adem, Mekete, Alem, Mohammed, Adnan Abdulkadir, Abdullahi, Yasir Younis, Adem, Ephrem, Siyoum, Eneyew Getachew, Zeleke, Ewunetu, Degefe, Derje Worku, Derilo, Habtamu, Eliyas, Nebiyu, Deressa, Yadani, Melese, Lemi, Muleta, Lemesa, Teshome, Abraham, Tesso, Birhanu, Gebrekirstos, Dr.Gebreagziabher, Pitkänen, Joel, Qian, Cheng, Sinikumpu, Jaakko, Dakpé, Stéphanie, Devauchelle, Bernard, Lavagen, Nolwenn, Bastard, François, Bin, Kim, Moukoko, Didier, Alshawared, Fadi, Beyrne, Carlos Daniel, Lugans, Laurene, Doussot, Alexandre, Onorati, Ilaria, Radu, Dana, André, Benoît, Marion, Herjean, Trilling, Bertrand, Boleslawski, Emmanuel, Noiret, Barbara, Aubry, Estelle, Subayi Nkembi, Armande, Christou, Niki, Usseglio, Julie, Jeandel, Clement, Denis, Waast, Duchalais, Emilie, Regenet, Nicolas, Rigaud, Jerome, Anract, Philippe, Dohan, Anthony, Cazelles, Antoine, Chamouni, Alexandre, Karoui, Mehdi, Mejean, Arnaud, Crétolle, Célia, Thouement, Clermidi, Pauline, Hervieux, Erik, Langlais, Tristan, Leonelli, Lorenzo, Thomin, Anne, Athiel, Yoann, Cathala, Nathalie, Levy-Zauberman, Yael, Macek, Petr, Mombet, Annick, Ollat, Didier, Fabrice, Chartier-Kastler, Emmanuel, Chereau, Nathalie, Melot, Charlotte, Turco, Célia, Chouillard, Elie, Boisson, Matthieu, Frasca, Denis, Livin, Marie, Mahmoud, Fedy, Sulpice, Laurent, Arnaud, Alexis P, Cazemajou, Clément Thierry, Nyangoh Timoh, Krystel, Renault, Annaëlle, Nappi, Francesco, Ezanno, Anne-Cecile, Cherkaoui, Zineb, Vix, Michel, Gornes, Hugo, Berthoumieu, Pierre, Misrai, Vincent, Pierre, Trocard, Angeles, Martina Aida, Del, Mathilde, Vancon, Antoine, Machemedze, Solomon, Muhemi, Roger, Ndizeye, Olivier, O’Connor, Jennifer, Tchoba, Simplice, Modabber, Ali, Schäfer, Benedikt, Wallqvist, Julia, Ziemann, Sebastian, Anthuber, Matthias, Broecheler, Tobias, Goßlau, Yvonne, Maksymiw, Florian, Sommer, Florian, Sommer, Björn, Loch, Florian N, Aghalarov, Ilgar, Braumann, Chris, Höhn, Philipp, Horn, Julian, Egger, Eva, Enderes, Jana, Strieth, Sebastian, Treede, Hendrik, Wittmann, Maria, Marche, Benedikt, Schulz, Sissy-Amelie, Fuchs, Hans, Bork, Ulrich, Meisel, Cornelia, Petzold, Andrea, Fluegen, Georg, Knoefel, Wolfram Trudo, Solodarenko, Oleksandra, Grützmann, Robert, Hackner, Danilo, Faqar-Uz-Zaman, Sara Fatima, Schnitzbauer, Andreas, Fung, Christian, Leiber, Christian, Neidert, Nicolas, Sandkamp, Richard, Schlager, Daniel, Strähle, Jakob, Spelsberg, Fritz, Becker, Johannes, Gonschor, Bernhard, Herbolzheimer, Marit, Keppler, Lena, Hecker, Matthias, Reichert, Martin, Sander, Michael, Schmidt, Götz, Schneck, Emmanuel, Kleeff, Jorg, Lorenz, Kerstin, Ronellenfitsch, Ulrich, Thomssen, Christoph, Dumpies, Christian W., Fischer, Isabel, Gessner, Michael, Klauke, Friederike, Schmidt, Birte, Vinz, Franziska, Sander, Johannes, Betz, Christian Stephan, Bewarder, Julian, Burg, Simon, Klatte, Till Orla, König, Daniela, Köpke, Leon-Gordian, Stangenberg, Martin, Roux, Frederic, Hakami, Ibrahim Abdullah, Mall, Julian W, Graeb, Christian, Huber-Strößner, Kristin, Pempe, Christina, Kelly, Kathrin, Siebert, Julia, Agrawal, Rachit, Gousias, Konstantinos, Qureischie, Homeira, Meyer, Frank, Rissmann, Anke, Turial, Salmai, Al-Nawas, Bilal, Battista, Marco Johannes, Heider, Julia, Mueller, Lena Katharina, Jentschura, Sina- Louisa Patrizia, Kowalewski, Karl-Friedrich, Rassweiler-Seyfried, Marie-Claire, Reissfelder, Christoph, Rotter, Nicole, Scherl, Claudia, Seyfried, Steffen, Fichter, Andreas, Gempt, Jens, Schäffer, Christoph, Wegmann, Helmut, Aghamaliyev, Ughur, Böcker, Wolfgang, von Ehrlich-Treuenstätt, Viktor H., Ladurner, Roland, Schlager, Justin Gabriel, Smolka, Wenko, Glowalla, Claudio, Schneidmueller, Dorien, Henkel, Karl Wilhelm, Stadler, Josef, Hölz, Katharina, Brunner, Stefan M., Prantl, Lukas, Herzberg, Jonas, Kröger, Marie, Niemeier, Andreas, Sras, Yara, Reinhard, Tobias, Löffler, Markus W., Steidle, Christoph, Dayan, Davut, Greve, Jens, Löbig, Niklas, Schochter, Fabienne, Wezel, Felix, Pusch von, Silke, Schmidbauer, Stefan, Boenicke, Lars, Degener, Stephan, Seiberth, Rose, Smit, Marieke, von Rundstedt, Friedrich-Carl, Germer, Christoph-Thomas, Lock, Johan, Lotz, Christopher, Schlesinger, Tobias, Schmid, Benedikt, Treutlein, Agnes, Agyeman-Duah, Nana Kwaku, Appiah, Enoch, Gakpetor, Delali, Minlah Allah, Stephen, Adu-Aryee, Nii Armah, Agboadoh, Nelson, Bediako Bowan, Antoinette, Brown, George Darko, Clegg-Lamptey, Joe-Nat, Fenu, Benjamin Sena, Kumassah, Philemon, Hussey, Romeo, Agbeno, Evans Kofi, Amoako-Boateng, Mabel, Debrah, Samuel, Doku, Dr Kingsley, Mensah, Philip, Nortey, Michael, Opandoh, Isabella Naa Morkor, Yigah, Makafui, Jiagge, Nuna, Acquaye, Jane, Agyemang-Prempeh, Akosua, Amo-Antwi, Kwabena, Amoah, Michael, Amoah, George, Aning, Daniel Gyawu, Annor Mintah, Dominic, Arthur, Joshua, Darko- Asante, Regina, Gaveh, Valerie, Gyamfi, Frank Enoch, Jonathan, Boakye - Yiadom, Konney, Thomas Okpoti, Kyei, Ishmael, Nimako, Boateng, Ofosu-Barko, Ben Blay, Osabutey, Anita, Sagoe, Robert, Yifieyeh, Abiboye, Ansong, George, Abdul-Mumin, Alhassan, Amadu, Munira, Azahares Leal, German, Buunaaim, Alexis, Cheyuo, Ernest, Daboo Salifu, Latif, Issaka, Adamu, Yakubu, Musah, Grypiotis, Ioannis, Papadopoulou, Triada, Korkolis, Dimitrios, Thomakos, Nikolaos, Dellaportas, Dionysios, Dimitra, Papalouka, Hadjizacharias, Theodoros, Konstadoulakis, Manousos, Massaras, Dimitrios, Vezakis, Antonios, Avgerinos, Konstantinos, Kechagias, Aristotelis, Ioannidis, Argyrios, Patelis, Nikolaos, Deskou, Eirini, Stamos, Nikolaos, Tasis, Nikolaos, Danias, Nikolaos, Selmani, Jonida, Kalamatianos, Theodosis, Stranjalis, George, Kondilis, Panagiotis, Kanellopoulou, Vasiliki, Larentzakis, Andreas, Papanikolaou, Vasileios, Potamianos, Spyridon, Triantafyllou, Tania, Panagiotou, Peter, Avramidis, Emmanouil, Bessias, Nikolaos, Tsiantoula, Paraskevi, Charalabopoulos, Alexandros, Kykalos, Stylianos, Kyros, Eleandros, Machairas, Nikolaos, Mastoraki, Aikaterini, Papalampros, Alexandros, Terras, Alexis, Tsourouflis, Gerasimos, Zografos, Constantinos, Antzaka, Christina, Falara, Areti, Perreas, Konstantinos, Rellia, Panagiota, Tasouli, Androniki, Skolarikos, Andreas, Tzelves, Lazaros, Theodorakis, Emmanuel, Karona, Paraskevi, Tzouganakis, Angelos, Chrysos, Emmanuel, Nikolouzakis, Taxiarchis, Tourountzi, Paraskevi, Al, Aggeliki, Kalfountzos, Christos, Arnaoutoglou, Eleni, Christodoulidis, Gregory, Gkolias, Nick, Hajiioannou, Jiannis, Krestinidis, Giorgos, Ntalouka, Maria, Saini, Fani, Skoulakis, Charalampos, Terzoudis, Christos Dimitrios, Zacharoulis, Dimitris, Δακής, Κωνσταντίνος, Filo, Eva, Kontopoulou, Konstantina, Patoulias, Ioannis, Astreidis, Ioannis, Christidis, Panagiotis, Loutzidou, Lydia, Mantevas, Antonis, Tatsis, Dimitris, Tsakiridis, Ioannis, Iordanidou, Eirini, Brolo, Estuardo, Gutiérrez Ruiz, Alitza, De León Lima, María Alejandra, Flores, Mario-Andrés, Morales, Steffanía, Rivera, Pablo, Rodas, Lesly, Santos, Victor, Sosa, Dianne, Barrios Duarte, Amalia, Talé-Rosales, Luis-Fernando, Villeda, Sergio Alejandro, Anicetti, Joshua, Lowey, Megan, Ardebol, Javier, Barillas, Kathia, Barillas, Sabrina, Recinos, Salvador, Hon, Sophie, Liu, Alex Qinyang, Liu, Shirley, Ip, Ho Wai, Mak, Brian, Mok, Chung Ying, Wong, Kiu Fung, Au-Yeung, Kit Ying, Chan, David Yuen Chung, Chiu, Wang Kei, Ho, Jacky Yan Kit, Kung, Janet Wui Cheung, Ling, Samuel Ka Kin, Lok, Hon Ting, Teoh, Jeremy Yuen-Chun, Wong, Randolph, Antal, Zsuzsanna, Bahrehmand, Kiarash, Sztipits, Tamás, Hidi, László, Piros, Laszlo, Rózsa, Balazs, Herczeg, György, Saftics, György, Kulcsicka-Gut, Judit, Sipos, Zsófia, Majmudar, Hardil, Madabhavi, Irappa, G S, Anitha, Kesarla, Venkatesh, Kumar Venkatappa, Sunil, P B, Hareesh, Shivashankar Chikkanayakanahalli, Santhosh, Sunil, Tanvi, Rajagopal, Niranjana, P L, Thirumanikandan, Mishra, Nitu, Wadhwani, Dr Rekha, Dhurwe, Ritika, Pushpalatha, Kameshwarachari, Raj, Sumit, Singh, Pooja, Kumar, Pankaj, Mittal, Yash, Panigrahi, Sibasish, Parija, Sucheta, Patra, Saroj, Sahu, Rabi, Sultania, Mahesh, Tripathy, Sujit, Kansay, Rajeev, Gupta, Sunil Kumar, Kaman, Lileswar, Salunke, Pravin, Singh, Kavindra, Rela, Mohamed, Goudar, Swati, B, Barani kumar P, Murugesan, Anandan, Subbian, Anbukkani, Kumar, Arvind, Chauhan, Tapan singh, Govil, Akhil, Gupta, Shubhra, Sharma, Ashish, Tiwari, Saurabh, Vishwani, Vartika, Evelyn. R, Nissi, Deb, Mainak, Jayaram, Harish, Nagpal, Pooja, Pathak, Prachi, Choudhary, Gautam Ram, Chugh, Ankita, Elhence, Abhay, Madduri, Vijay, Pandey, Himanshu, Saxena, Rahul, Sharma, Naveen, Shekhar, Shashank, Vishnoi, Jeewan Ram, Bhende, Vishal, Chatterjee, Debarshi, Ghosh, Indranil, Naskar, Upasana, Jain, Prateek, Jain, Deepak, Kewlani, Vishal, Priya, Noopur, Parijat, Anand, Anand, Akshay, Bajaj, Ankur, Chaurasia, Akhilanand, Enny, Loreno E., Kumar, Ambrish, Mishra, Brijesh, Pandey, Amita, Rajan, Shiv, Roy, Ashutosh, Sachan, Rekha, Sankhwar, Pushp, Singh, Uma, Singh, Urmila, Srivastava, Chhitij, Verma, Manju Lata, Yadav, Awdhesh, Agarwal, Gaurav, Chanthar, K.m.m.vishvak, Hoysal, Dileep, Mishra, Anjali, Batra, Nitin, Bhatti, Arun, Dhar, Tapasya, Dutta, Rohini, Haque, Parvez David, Jain, Ritu, Luther, Anil, Mahajan, Amit, Pargal, Dr Pinki, Samuel, Abhishek, Singh, Inderjot, Singh Grewal, Sarvpreet, Singhania, Anusha, Alexander, Philip, Thomas, Josy, Krishna, Sunil, Singh, Narinder, Agarwal, Sunny, Balasubramaniam, Srikant, Dharap, Satish, Mhamane, Rameshwar, Nirgude, Anand, Parab, Sandesh, Peswani, Amit, Sahu, Anjana, Samel, Sarika, Shah, Fagun, Abraham, Bejoy, Asari, Ashishkumar, Badhe, Vivek, Badhwar, Sanjiv, Bothara, Vipul, Dalal, Anuj, Date, Avinash, Deshpande, Mandar, Doshi, Anirudha, Gade, Maya, Gajjar, Shreyash, Ghugare, Dr bhavisha, Jain, Divakar, Jenasamant, Saumya Sekhar, Joshi, Vinay, Kalwadia, Neha, Kayal, Akshat, Kulkarni, Yogesh, Mistry, Rajesh, Mulchandani, Manoj, Parab, Dr. Mrunal, Pednekar, Abhinav, Rahmani, Faizan, Rajput, Sunil, Sandlas, Gursev, Sarkar, Hrishikesh, Shetty, Sanket sadanand, Shukla kulkarni, Anshumala, Thete, Raghavendraswami, Wasnik, Shruti, Dhumane, Parag, Sharma, Rahul Deo, Deshmukh, Anuja, Gupta, Stuti, Nayak, Prakash, Thiagarajan, Shivakumar, Tiwari, Virendra Kumar, Voppuru, Saiesh Reddy, Soni, Rajesh, Bajpai, Minu, Farooque, Kamran, Parshad, Rajinder, Sharma, Vijay, Bansal, Kuldeep, Bains, Lovenish, Bhardwaj, Rohit, Mittal, Abhishek, Ponnusamy, Sabarirajan, Ghodke, Rahul, Himani, Kumar, Ashwani, Gadekar, Anup, Panjwani, Taufiq, Maji, Suvendu, Basu, Somprakas, Kandwal, Pankaj, Kumar, Shashank, Poonia, Dharma Ram, Sadhasivam, Saravanan, Mahakalkar, Chandrashekhar, Choudhury, Yousuf, Das, Devishmita, Goala, Subhadra, Singha, S Thoibisana, Singha, Damayanti, Mehraj, Asif, Parray, Fazl, Shah, Raahil, Wani, Rauf, Hegde, Siddhi, Ankadavar, Dr.sushil, Bafna, Darshan, Lad, Parag, Chisthi, Meer, Jothi, Harihara, .C. Mathew, Godwin David, Abel, Livingston, Barla, Ravi Kishore, Benjamin, Santosh, Bliss, Jeremy, Ete, Geley, James, Deeptiman, Jesudason, Mark Ranjan, Karnan, Gomathi, Mark Samuel, Vasanth, Mittal, Rohin, Nathan, Senthil K, Selvaraj, Daniel, Surendran, Suraj, T D, Hariharan, Thangaraj, Santhosh Kumar, Thomas, Varghese, Dilmy, Mohammad Adya Firmansha, Pratama, Dedy, Sugiarto, Adhrie, Surya, Ilham Utama, Tango, Tamara, Hasyim, Andi, Susanti, Ade, Saputra, Teddy, Syarifuddin, Erwin, Islam, Andi Asadul, Anam, Khoirul, Sugianto, Julius Albert, Lestari, Mayang Indah, Amba, Erick Gamaliel, Apriawan, Tedy, Wathoni, Roidah Taqiyya Zahra, Widyastuti, Yunita, Yun Jufan, Akhmad, Etezadpour, Mohammad, Mehrad-Majd, Hassan, Rajaei, Parisa, Mehdizadeh, Mohammad, Soltani, Mina, Pour, Ali Moazami, Azarnia, Gholamreza, Alizadeh, Narges, Mokarami, Hossein, Tehrani, Shahrzad, Alborzi, Majid, Bagheri, Hamed, Eshraghi, Mohsen, Fatemi manesh, Hassan, Hejazi, Seyed fakhreddin, Pezeshki Modarres, Mahdi, Shafiee, Ali, Vafaeimanesh, Jamshid, Hosseini, Elahe, Nikoupour, Hamed, Bastaninejad, Shahin, Firouzifar, Mohammadreza, Motasaddi zarandy, Masoud, Yazdani, Nasrin, Yousefzadeh Kandevani, Naser, Mortazavi, SM Javad, Ahmadi, Sayedali, Khosravi, Mohammad Hossein, Vosoughi, Fardis, Golbakhsh, Mohammadreza, Al-Isawi, Ali, Al-Masood, Mohammed, Gahtan, Yarub, Ahmed, Abdullah, Hilmi, Ahmed, Muhssein, Haidar, McNestry, Catherine, Ekwere, Bosom, Essajee, Murtaza, Chan Chin, Bruno, Edwards Murphy, Amy, Fleming, Christina, Foley, Niamh, Gardiner, Padraig, Hechtl, Daniel, Kayyal, Mohd yasser, Lyons, Maria, O’Brien, Stephen, Ng, Mei Yee, Oduola, Oladayo, Aljohmani, Lylas, Nugent, Timothy, Harris, Johnathon, Kearney, David, Keenan, Robert Anthony, Nolan, Deirdre, Salloum, Croghan, Stefanie M, Donohoe, Emma, Larkin, John, Lynch, Thomas Hugh, Manecksha, Rustom, Nagassima, Katharina, Barry, Mary, Cullinane, Carolyn, Dowdall, Joseph, Hurson, Conor, Kelly, Orlaith, Kennelly, Rory, Kiernan, Aoife, Murphy, Ben, Njeze, Nwabundo, Reynolds, Ian Sean, Winter, Des, Ravi, Akshaya, Ridgway, Paul, Fowler, Amy, McAnena, Peter, Bahadoor, Muhammad Usaama, Kabir, Syed Mohammad Umar, Khalid, Mohamed Hamed, Mujtaba, Syed Nadeem, Sarwar, Muhammad assam, Sugrue, Michael, Varzgalis, Manvydas, Jones-Whiting, Larne, Lim, Seantee, Ryan, Éanna, Sara, Al-Mukhaizeem, Youssef, Crowley, Clare, Flanagan, Michael, Fogarty, Amy, Glynn, Orna, Hill, Rhodri, Khalid, Muhammad Abdullah, Majeed, Zubair, McCullough, Peter, Neary, Peter, Noone, Anthony, O’Kelly, John, Abu abed, Arsan, Haim, Nadav, Hershkovitz, Yehuda, Majadla, Omar, Rabin, Igor, Zmora, Osnat, Demma, Yonatan Avraham, Fishman, Yuri, Farkas, Amicur, Gozal, Yaacov, Greenman, Dmitry, Ostrovsky, Israel Alexander, Pardes, Rivka, Shahar, Tal, Teren, David, Yahud, Reuven, Yellinek, Shlomo, Cianci, Pasquale, Minafra, Marina, Restini, Enrico, Bussolin, Edoardo, De Prizio, Marco, Sulce, Rezart, Poiasina, Elia, Antonacci, Filippo, Arena, Alessandro, Belvedere, Angela, Bernagozzi, Fabio, Boussedra, Safia, Cescon, Matteo, Cipolli, Alessandro, Daddi, Niccolo’, De Crescenzo, Eugenia, De Iaco, Pierandrea, Del Gaudio, Massimo, Della Gatta, Anna Nunzia, Droghetti, Matteo, Giorgini, Federico A., Lanci Lanci, Antonio, Masetti, Michele, Minni, Francesco, Morezzi, Daniele, Perrone, Anna Myriam, Pignatti, Marco, Puglisi, Silvana Bernadetta, Rottoli, Matteo, Schiavina, Riccardo, Serenari, Matteo, Serra, Margherita, Tesei, Marco, Violante, Tommaso, Aspide, Raffaele, Carretta, Alessandro, Conti, Alfredo, De Vita, Carla, Friso, Filippo, La Corte, Emanuele, Rosetti, Vittoria, Sturiale, Carmelo, Donati, Davide Maria, Palmerini, Emanuela, Berselli, Bruno, Bolognesi, Silvia, Farnia, Francesco, Maremonti, Pietro, Razzaboni, Alessandra, La Mendola, Roberta, Arrigoni, Giulia, Baiocchi, Gian Luca, Molfino, Sarah, Panciani, Pier Paolo, Sartori, Enrico, Zanin, Luca, Perrone, Fabrizio, Cappellani, Alessandro, Giaquinta, Alessia, Gioco, Rossella, Veroux, Pierfrancesco, Cianci, Antonio, Lo Giudice, Arturo, Russo, Giorgio Ivan, Sarpietro, Giuseppe, Scandura, Carmen Emanuela, Barca, Ida, Carnevali, Adriano, De Paola, Gilda, Giannaccare, Giuseppe, Sammarco, Giuseppe, D’Andrea, Marcello, Tosatto, Luigino, Mucilli, Felice, Muraglia, Angelo, Giuliani, Domenico Benvenuto, Segalini, Edoardo, Daniele, Alberto, Gelarda, Enrico, Olearo, Elena, Puppo, Andrea, Testa, Valentina, Porta, Andrea, Birindelli, Arianna, Bernabei, Massimiliano, Feo, Carlo V., Virgilio, Edoardo, Bartolini, Ilenia, Bottari, Andrea, Checcucci, Carlotta, De Vincenti, Rosita, Fambrini, Massimiliano, Fortuna, Laura, Gallo, Oreste, Maltinti, Gherardo, Taddei, Antonio, Michelagnoli, Stefano, Maccagnano, Giuseppe, Pesce, Vito, Ercolani, Giorgio, Fappiano, Francesca, Barberis, Andrea, Filauro, Marco, Santoliquido, Matteo, Aprile, Alessandra, Barra, Fabio, De Rosa, Raffaele, Ferrero, Simone, Sparavigna, Marco, Vagge, Aldo, Gambardella, Denise, Tedesco, Manfredo, Spampinato, Marcello Giuseppe, Chiarelli, Marco, Grandi, Samuele, Lenzi, Riccardo, Muscatello, Luca, Germano’, Antonino Francesco, Giani, Alessandro, Bissacco, Daniele, Cassinotti, Elisa, Pignataro, Lorenzo, Torretta, Sara, Armellin, Daniele, Basato, Silvia, Carrano, Francesco Maria, Colombo, Giovanni, De Lucia, Francesca, De Virgilio, Armando, Ferreli, Fabio, La Raja, Carlotta, Milana, Flavio, Rossi, Vanessa, Russo, Elena, Tamburello, Sara, Zerbi, Alessandro, Bona, Davide, Adamoli, Laura, Ansarin, Mohssen, Chu, Francesco, De Berardinis, Rita, Pietrobon, Giacomo, Sedda, Giulia, Caputo, Maria, Cellerino, Paola, Crespi, Michele Achille, Danelli, Piergiorgio, Ferrara, Francesco, Baccellieri, Domenico, Candiani, Massimo, Casiraghi, Arianna, Cipriani, Federica, De Nardi, Paola, Mortini, Pietro, Nocera, Gianluca, Pozzoni, Mirko, Ruffolo, Alessandro Ferdinando, Spina, Alfio, Barberio, Cristina, Beretta, Luigi, Cavenago, Francesca, Fresilli, Stefano, Landoni, Giovanni, Lombardi, Gaetano, Bonomi, Stefano, Guaglio, Marcello, Sala, Laura, Segattini, Silvia, Piccoli, Micaela, Migliore, Marco, Sasia, Diego, Cereda, Marco, Dell’Oro, Cristina, Fogliati, Alessandro, Tamini, Nicolò, Castaldi, Antonio, Bracale, Umberto, Lionetti, Ruggero, Pagano, Gianluca, Peltrini, Roberto, Pirozzi, Nello, D’amico, Maria, Izzo, Francesco, Marra, Ester, Marte, Gianpaolo, Bianco, Francesco, Cappiello, Antonio, Iovino, Claudio, Menna, Maria Paola, Romano, Francesco maria, Rossi, Settimio, Sciaudone, Guido, Ascari, Francesca, Bellora, Paolo, Cerri, Cristina, D’Aloisio, Giordana, Ferrari, Maurizio, Chioffi, Franco, Ciccarino, Pietro, Nezi, Giulia, Bissolotti, Guido, Di Donna, Mariano Catello, Licari, Leo, Salamone, Giuseppe, Toia, Francesca, Annicchiarico, Alfredo, Berretta, Roberto, Capozzi, Vito Andrea, Freyrie, Antonio, Frusca, Tiziana, Arici, Vittorio, Bozzani, Antonio, Filardo, Matteo, de Manzoni Garberini, Andrea, Cauteruccio, Michele, Caristo, Giuseppe, Calabrò, Marcello, Andreani, Lorenzo, Antonio, D’arienzo, Berrettini, Stefano, Colangeli, Simone, Cremonini, Camilla, Dallan, Iacopo, Di Franco, Gregorio, Korasidis, Stylianos, Musetti, Serena, Neri, Carlo Maria, Palmeri, Matteo, Picariello, Miriana, Statuti, Erica, Tartaglia, Dario, Pinotti, Enrico, Basso, Stefano Maria Massimiliano, Ubiali, Paolo, Coiro, Saverio, Mele, Simone, Corbellini, Carlo, Masciandaro, Antonio, Carannante, Filippo, Denaro, Vincenzo, Mazzotta, Erica, Zampogna, Biagio, Cinquepalmi, Matteo, Del Basso, Celeste, Guglielmo, Nicola, Meniconi, Roberto Luca, Sinibaldi, Giovanni, Agnes, Annamaria, Belia, Francesco, Bianchi, Valentina, Cozza, Valerio, Fico, Valeria, Fransvea, Pietro, La Greca, Antonio, Litta, Francesco, Pascale, Marco Maria, Silvia, Tedesco, Benevolo, Maria, Campo, Flaminia, Dona’, Maria Gabriella, Marchesi, Paolo, Mastroianni, Riccardo, Mazzola, Francesco, Moretto, Silvia, Petruzzi, Gerardo, Pichi, Barbara, Tuderti, Gabriele, Bellato, Vittoria, Grande, Michele, Petagna, Lorenzo, Sensi, Bruno, Bruzzaniti, Placido, Ciccarone, Flavia, Cicerchia, Pierfranco Maria, Cirillo, Bruno, D’ambrosio, Giancarlo, De Toma, Giorgio, Familiari, Pietro, Fonsi, Giovanni Battista, Pata, Francesco, Picchetto, Andrea, Salvati, Maurizio, Valentini, Valentino, Zambon, Martina, Zancana, Giuseppa, Zuppi, Emma, Ibrahim, Mohsen, Menna, Cecilia, Rendina, Erino Angelo, Accarino, Giulio, Giancarlo, Accarino, Froiio, Caterina, Copelli, Chiara, Di Maio, Pasquale, Giudice, Marco, Altana, Cristian, Ciccarello, Sandro, Cossu, Maria Laura, Dessole, Francesco, Dettori, Salvatora, Madonia, Massimo, Petrillo, Marco, Piredda, Franco, Rizzo, Davide, Scognamillo, Fabrizio, Soma, Damiano, Tanca, Anna Rita, Marano, Luigi, Pesce, Anna Lisa, Piccioni, Stefania Angela, Resca, Luca, Roviello, Franco, Abrate, Alberto, Clarizia, Guglielmo, Franzini, Marco, Fratto, Antonio, Grechi, Alessandro, Scarnecchia, Elisa, Maiuri, Vincenzo, Dalprà, Francesca, Battistella, Enrico, Romano, Maurizio, Aizza, Giada, de Manzini, Nicolò, Drigo, Davide, Mastronardi, Manuela, Palmisano, Silvia, Bardelli, Laura, Borroni, Giacomo, Livraghi, Lorenzo, Palumbo, Mara, Zullo, Alessandra, Vignotto, Chiara, Caravati, Andrea, De Cristofaro, Carlotta, Giuliani, Tommaso, Guglielmi, Alfredo, Pedrazzani, Corrado, Butturini, Giovanni, Moretto, Gianluigi, Mastriale, Francesco, Olmi, Stefano, Kushikata, Tetsuya, Oyama, Tasuku, Kamiyama, Mizue, Tarao, Kentaroh, Yamada, Takayuki, Shiga, Toshiya, Deguchi, Yoshihiko, Hoshino, Tatsuki, Inoue, Hiroyuki, Ito, Shingo, Takano, Emi, Yamamoto, Masae, Matsuki, Yuka, Matsumoto, Takashi, Sawada, Atsushi, Sato, Kozo, Makino, Jun, Mizota, Toshiyuki, Yonekura, Hiroshi, Ishikawa, Haruka, Kaiho, Yu, Ogawa, Munehiro, Endo, Shunji, Fujiwara, Yoshinori, Kubota, Hisako, Okada, Toshimasa, Hisamatsu, Yoji, Michiura, Taku, Satoshi, Okazaki, Fujita, Tomoyuki, Fukushima, Satsuki, Otsuka, Yuji, Sawada, Ikumi, Miyamoto, Morikazu, Isada, Tetsuro, Bani Amer, Qaed, Fujimoto, Yuki, Kuratani, Norifumi, Takada, Misa, Noro, Shusaku, Kuroda, Naoto, Okamura, Yukiyasu, Uesaka, Katshuhiko, Kuroda, Kento, Abe, Nobutsugu, Ando, Tadao, Hirano, Kouichi, Kobayashi, Yoichi, Motoyasu, Akira, Noguchi, Hikari, Tajima, Atsushi, Toyama, Satoshi, Uchida, Tokujiro, Furukawa, Yuri, Hasumi, Yoko, Iida, Katsuyuki, Ikeda, Tatsuhiko, Kuzuhara, Shigeki, Yamamoto, Naoya, Yamamoto, Mari, Yokota, Toshiya, Yoshioka, Yuki, Kawai, Akira, Nakata, Yoshinori, Sawamura, Shigehito, Kobayashi, Takayuki, Alqudah, Majdi Ali, Alrabadi, Mera, Owais, Qais, Smadi, Aseel, Abunawas, Huthifa, Alhawatmeh, Mohammad, Alwardat, Abdel Rahman Mohannad Ahmad, Dhoon, Slsabela, Jaradat, Enas, Mubaydeen, Teeba, Alzraikat, Sayel H., Omari, Rand Y., Suradi, Haya H., Al Abdallah, Murad, Al Bdour, Zakaria, Al-thaher, Mohammad, Alnajjar, Tareq, AlZaatreh, Mohammad, Ayasra, Faris, Ghayada, Ibrahim, Hasanein, Khaled Moh’d Ahmed, Hassouneh, Anas, Hijazeen, Raid, Khasawneh, Barihan, Semrin, Qusai, Theab, Mohammad, Abazeed, Alaa, Alkurdieh, Moh’d Mujahed, Hammouri, Mohammad, Khader, Sereen, Abu Obead, Hamza, Abudari, Hadeel, Al-azzeh, Nimer, Al-Darabah, Ali, Al-Qannas, Mohammad, Ashour, Subhi, Chabaan, Reem, Fawzi, Ahmad, Haij, Manal, Hassouneh, Esraa, Ibrahim, Zainab, Mohamed, Ishak, Qandeel, Mahmoud, Qassem, Faisal, Shorman, Marwan, Nofal, Sandra, Salameh, Mohammed, Sanjuq, Ghaidaa, Sharabi, Alaa, Sweiti, Alaa, Baninasr, Eman, Abuleil, Amro, Abou Chaar, Mohamad K., Al-latayfeh, Motasem, Al-Shudifat, Abdel-Ellah, Shaikh Ahmad, Abd Almonem, Abu Abed, Laith, Allouzi, Mohammad, Almi’ani, Sari, Alsaiad, Abdulhakim, Daoud, Maher, Dawod, Omar, Fadli, Saba, Jimaale, Elmi Ahmed Mohamed, Qulaghassi, Zaki, Al-howthi, Mohammed, Ababneh, Laila, Ababneh, Roba, Al Khassawneh, Ahmad, Al Sharie, Ahmed, Al-Dabaa, Tawfik, Al-Jarrah, Salsabeel, Alshannaq, Qutaiba, Alsulaiman, Rima, Audat, Ziad, Bdour, Saja, Khatatbeh, Ro’a, Marji, Fares, Abu Ismail, Dima.Y, Abu-Ismail, Luai, Alzoubi, Mai, Alzoubi, Malak, Hussein, Hasan, Rawashdeh, Shireen, Ababneh, Adnan, Abu-Eisheh, Basil, Al Shurman, Hana’, Al-atiyah, Hussam, Aljaiuossi, Anas, Hamdoni, Sara, Kulimbet, Mukhtar, Sakhov, Orazbek, Fakhradiyev, Ildar, Tanabayeva, Shynar, Zhussupov, Baurzhan, Amrayev, Sultan, Kukubassov, Yerlan, Parker, Robert, Mwaria, Claude, Kibunyi, Muthoni, Mailu, Claire, Osea, Lydia, Hirsi, Omar, Dashti, Mustafa, Aldalal, Shuaib, Alozairi, Ous, Al-Shaiji, Tariq, Alhunaidi, Omar, Aljewaied, Ali, Farag, Ahmed, Termos, Salah, Sivins, Armands, Apse, Ingus Arnolds, Kaminskis, Aleksejs, Pāvulāns, Jānis, Itani, Rania, Owiedat, Mustafa, Antonios, Ingrid, Milan Moussa, Rita, Abdel Sater, Ali H., Souleiman, Bassem, Ghiya, Peter, Fakih, Ghinwa, Tamoos, Khalil, Abdulrahman, Taha, Omar Abunaaja, Hayat, Al Gasi, Abd El Jawad, Al maadany, Faraj, Alsaeiti, Sara, Elkhafeefi, Fatimah, Alhouni, Tarek, Alkeelani, Hana, Alkuwafi, Rauoof, Elbargathe, Osama, Elfadli, Mustafa, Elmahgoub, Asma, Alansari, Arowa hassan abdulrahman, Alhaje, Awatif, Haron, Aaya, Alsuwiyah, Suhir, Khel, Samer, Yousef, Rowaida, Abuhlaiga, Ma’aly, Abushahma, Ahmed omar, Aldelensi Alzubi, Alhosen Saleh M, Alnehum, Mohamed alnaser, Alzedam, Ahmad, Matoug, Faisel, Mohammed, Burooj, Sawalem, Mohamed, Kamoka, Elhusain, Salamah, Abdulrauf, Abdeewi, Saedah, Eshnaf, Mabroka, Yahmad, Mohammad, Aljuroushi, Omar, Attia, Hajer, Emran, Ayyah, Samer, Ashraf, Abdullah, Duha milad, Ben esmael, Esraa, Benmasoud, Fatma, Debri, Laila, Younis, Balkees, Elmabrouk, Amna, Hasan, Ameerah Mahdi Abraheem, Suliaman, Taha, Alawami, Mohammed, Alshareea, Entisar, Aribi, Tomather, Lamari, Amani hamid, Mufth, Mohammed, Aburima, Sarah, Al shukri, Asmaa, Alarabi, Rehab, Alelwany, Aisha, Bashir, Rasha, Elhadi, Ahmed, Elkouba, Esraa, Ellojli, Ibrahim, Elmsherghi, Nabiha, Haidar, Arwa, Helal, Hala, Kriem, Eslam, Turshani, Laila, Alayan, Mohammed, Ben Hasan, Hayat, Shaban Ben Hasan, Najat, Shaban Ben Hasan, Rabab, Dambrauskas, Zilvinas, Dekeryte, Inga, Koženiauskaitė, Akvilė, Maleckas, Almantas, Venclauskas, Linas, Zilinskas, Justas, Syminas, Vilius, Aliosin, Oleg, Cizauskaite, Agne, Jurgaitis, Jonas, Mikutaitis, Vytenis, Samalavicius, Narimantas Evaldas, Slepavicius, Algirdas, Vasiliauskas, Bernardas, Dulskas, Audrius, Cekauskas, Albertas, Gulla, Aiste, Zelvys, Arunas, Noël, Audrey, Rajaonarivony, Maheriandrianina Fanambinana Voahary, Andriantsoa, Herimampionona E, Samison, Luc Hervé, Tsiambanizafy, Guillaume Odilon, Solo, Corinne Eulalie, Safiry Andofenohasina, Fanonjomahasoa, Sablon Herinirina, Angelin, Das, Andre, Osman, Mohd Firdauss, Soh, Jien Yen, Zakaria, Zaidi, Chan, Kheng Hooi, Johan, Syamim, Mah, Jin Jiun, Subramaniam, Sentilnathan, Ibrahim, Mohd Razali, Nazimi, Abd Jabar, Bal, Pavin, Fadzli, Ahmad nazran, Jamaris, Suniza, Lee, Yeong Sing, Lim, Jeffery Zk, Moh Pauzi, Siti Farhan, Nair, Ashvin Krishna, Ng, Doris Sin Wen, Ng We Yong, Yuki Julius, Roslani, April Camilla, Saaid, Rahmah, Sethi, Neha, Syed Jafer Hussain Zaidi, Syeda Nureena, Teoh, Li Ying, Munjih, Islah, Sainal, Mohd Yusof, Sarif, Mat Salleh, Chua, Richelle, Ahmad, Abdul 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Gabriela, Morales valencia, Eduardo, Santos, Blanca, Torres Cisneros, Juan Roberto, Bozada-Gutiérrez, Katya, Alvarez, Maria Regina, de la Rosa Abaroa, Marco Antonio, Hernandez, Roberto, Bernardo, Anaya, Ernesto, Arceo-Olaiz, Ricardo, Lopez Flores, Sonia, Esparza Arias, Nereida, Romero Bañuelos, Esmeralda, Salcedo-Hernández, Rosa, Buerba, Gabriela Alejandra, Chan, Carlos, Garay Lechuga, Daniel, Hinojosa, Carlos, Mercado, Miguel Ángel, Peña Gómez Portugal, Emmanuel, Posadas-Trujillo, Oscar Emmanuel, Hernandez Skewes, Karla Yareli, Licona-Meníndez, Roque Delfino, Romero Lechuga, Fernanda, Roque, Oscar, Núñez-González, Roberto Ángel, Alvarez Manilla Orendain, Alfonso, Garcia, Felipe, González León, Juan Antonio, Guzman, Marlin, Herappe, Dorihela, Lerma, Ricardo, Mendoza Pedraza, Fabián Hilario, Noguez Castillo, Monica, Resendiz, Jose Anatolio, Fernandez Rios, Laura Elena, Frigerio, Pamela, Garcia, Iset, Mendoza Frías, Gloria Isela, Anzures Mendoza, Alejandra, Hdez Miguelena, Luis, Zarate 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Blasius, Abdulsalam, Khalifa, Agida, Eyaofun, Ajibola, Hafees, Benard, Adeka, Buba, Amina, Eniola, Sefiu, Isah, Aliyu, Olute, Anne, Osagie, Olabisi, Pius Ogolekwu, Idoko, Ademola, Samuel, Afuwape, Oludolapo, Daodu, Israel, Egbuchulem, Ifeanyichukwu Kelvin, Lawal, Taiwo Akeem, Nwaorgu, Onyekwere, Obadan, Izegaegbe, Odeyemi, Olubunmi, Ogundoyin, Omowonuola, Okere, Oghenekevwe, Oladiran, Ajibola, Olagunju, Naomi, Olawoye, Olayinka, Olusanya, Adeola, Oyelakin, Oyeleye, Ugwu, Ebere, Ademuyiwa, Adesoji, Atoyebi, Oluwole, Bode, Chris, Chibuike George, Ihediwa, Ezenwankwo, Francis, Fatuga, Adedeji, Ladipo-Ajayi, Oluwaseun, Ojewola, Rufus Wale, Okunowo, Adeyemi, Seyi-Olajide, Justina, Ugwu, Aloy Okechukwu, Adebara, Idowu, Adeyemo, Olabisi, Banjo, Oluseyi, Obateru, John, Ojo, Owolabi, Okunlola, Abiodun, Oluwafemi, Fatudimu, Adelaja, Aderinsola, Atobatele, Kazeem, Ayodele, Olabamidele, Bello, Funmi, Omisanjo, Olufunmilade, Aderounmu, Adewale, Adisa, Adewale, Ajekwu, Temitope, Ajekwu, Samuel, Akeem Aderogba, Adeleke, Balogun, Simon, Ojo, Olugbenga, Olasehinde, Olalekan, Olugbami, Adebayo, Wuraola, Funmilola, Mohammed, Tajudeen, Afolabi, Abdulrahman O., Aremu, Isiaka, Ibraheem, Gbadebo, Odeyemi, Peter Olalekan, Olabinjo, Afusat, Raji, Hadijat Olaide, Salawu, Hafeez, Uche-Okonkwo, Kenechukwu, Anipole, Olalekan, Adesina, Oluwaseyi, Enwerem, Kenneth, Isichei, Mercy, Aghadi, Ifeanyi, Kache, Stephen, Lawal, Jamila, Taingson, Matthew, Yusuf, Nuhu, Sale, Danjuma, Takai, Idris Usman, Aji, Sani Ali, Anyanwu, Lofty-John, Bello-Muhammad, Nafisatu, Garzali, Ibrahim Umar, Hasheem, Muhammad Ghazali, Hassan, Sadiq, Ibrahim Usman, Mustapha, Magashi, Mahmoud Kawu, Mukhtar, Ibrahim Aliyu, Nwachukwu, Callistus, Suleiman, Ibrahim, A, Maryam, Mahmood, Farrukh, Salihu, Mohammed, Okereke, Chukwuma, Alegbeleye, Justina Omoikhefe, Awopeju, Abimbola, Fyneface-Ogan, Sotonye, Kasso, Terhemen, Onwuagha, Ijeoma, Salami, Babatunde, Ajagha, Okeoghene, Awaisu, Mudi, Nwabuoku, Stanley Emeka, Oyelowo, Nasir, 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Pereira, André, Pereira-Neves, António, Pina-Vaz, Teresa, Pinheiro, Gabriela, Pinho, Sílvia, Ramos, Pedro, Ramos, Patricia, Vilares Morgado, Rodrigo, Canotilho, Rita, Correia, Ana Margarida, Ferreira Pinto, Ana Paula, Claro, Mariana, Costa Santos, Daniel, Boto, Carlos, Branquinho, Rita, Rodrigues, Sónia, Guidi, Gonçalo, Leal, Clara, Machado, Luís, Marques, Prescillia, Martins, Daniela, Morais, Mariana, Nunes, Sara, Sapage, Rita, Sousa, Rita, Sousa, Diogo, Vaz Pereira, Ricardo, Lima Oliveira, Susana, Abdalla, Samir, Aurif, Fahad, Muzaffar, Nasir, Ahmed, Khalid, Al Dosouky, Mohammed, Al-Tarakji, Mohannad, Almudares, Saif, Elaffandi, Ahmed, Muslim, Muhammad, Qabbani, Amjad, Shah, Amjad, Khan, Mohammad Burhan, Murad, Musab, Costache, Victor, Dumitrescu, Tudor Ștefan, Muntean, George-Ovidiu, Mironescu, Aurel, Bezede, Cosmin, Enciu, Octavian, Baraian, Sergiu Catalin, Niculae, Cristina, Filipescu, Daniela, Goicea, Raluca, Alexe, Vlad, Batog, Olivia, Iliescu, Madalina, Ionescu, Sebastian, 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Rayzah, Musaed, Abd ElGhany, Reda, Al Ameer, Ahmed, Bawa, Dauda, Elzain, Mohammed, Wakill, Fadi, Fahiem-ul-Hassan, Mir, Al Duhileb, Mohammed, Alazzeh, Ghaleb, Alghazal, Thabet, Alkhatib, Abdulrahman, Almatar, Bikheet, Alnaimi, Manal, Alsuwaimel, Munir, Balhareth, Ameera, Abutaleb, Malak, Ageeli, Mohammed, Alhazmi, Barrag, Alkhayrat, Saud, Miftah, Mohammed, Otayfah, Sameer, Sari, AbdulRahman, Alsadiq, Mohammed, Fouad, Mohammed, Iskander, Othman, Al Athath, Samer, Alharthi, Mohammed, Bayazid, Muhannad, Al-Radi, Osman, Altaf, Abdulmalik, Arab, Fatima, Bangash, Mohammed, Basendowah, Mohammed, Farsi, Deema, Farsi, Ali, Habeebullah, Alaa, Malibary, Ziad, Nassif, Mohammed, Nawawi, Anfal, Sabbagh, Abdulrahman J, Sait, Salma, Saleem, Abdulaziz, Trabulsi, Nora, Alghamdi, Abdulaziz, Altalhi, Bassam, Alzaidi, Turki M, Mughal, Samiullah, Samadony, Mustafa, Althobaiti, Awwadh, Hakami, Hadi, Al Jamahir, Mohammed, Al Wadei, Hajr, Al-Qannass, Ali, Al-Qurashi, Qusay, Albakry, Ibrahim, Alkarak, Samer, Alkhanbashi, Omar, Alqannas, Mashhour, Alsakkaf, Mazen, Alzamanan, Mohammed, Mahnashi, Taher, Mohammed, Rawabi, Taha, Youssef, AlAamer, Ohood, Alaglan, Abeer, Alriyees, Lolwah, Alromaihi, Meaad, Alsafi, Maryam, Alsahabi, Jawaher, Alselaim, Nahar, Bin Saad, Khalid, Binjaloud, Ahmed, Dagestani, Hattan, Abaalkhail, Muath, Abukhater, Muhammad, Al Saied, Ghiath, Albarrak, Majed, Alghamdi, Ahmad, Alhogbani, Mofarej, Ali, Aisha Mansoor, Almushawah, Fatema, Alqahtani, Loai, Alqasem, Saad, AlRayih, Mohammed, Alsaleh, Khaled, Alsamari, Alanoud, Alshammari, Abdulaziz, AlSolami, Zeyad, AlSubaie, Fahd, Alsuliman, Yazeed, Alsuwaydani, Saleh, Alzahrani, Saud, Alanoud, Abu-Zaid, Ahmed, Aburahmah, Mohammad, Al Humaid, Lama, Al-Qattan, Mohammad, Alabbasi, Amira, Alahmari, Ahmed, Alaqel, Sara, Alassiri, Ali, Aldaghiri, Khalid, Alhaidari, Ammar, Alhazmi, Alaa, Alhazzaa, Norah, Alhefdhi, Amal, Alhelal, Boshra, Alhuthayl, Meshari, Alkassim, Abdullah, Alkhayal, Wafa, Almalaq, Ali, Almalik, Osama, AlMarshad, 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Alobaysi, Saad, Modahi, Nawaf, AI Nwijy, Khaled, AI Zahrani, Turki, Alahmad, Feras, Alalawi, Dr Yousef, Awaji, Ahmed, Emara, Sherif, Musawa, Nizar, Zakaria, Mahmoud, Althobaiti, Waleed, Paunovic, Ivan, Alajaji, Nouf, Ivanović, Nenad, Kmezić, Stefan, Knezevic, Djordje, Krivokapic, Zoran, Latinčić, Stojan, Markovic, Velimir, Miladinov, Marko, Ninic, Aleksandar, Gregoric, Pavle, Loncar, Zlatibor, Bogdanovic, Ivan, Milisavljević, Filip, Paunovic, Aleksandra, Trivic, Aleksandar, Bumbasirevic, Uros, Lazic, Aleksandar, Djurisic, Igor, Jevric, Marko, Kocic, Milan, Kozomara, Zoran, Markovic, Ivan, Dejanovic, Tatjana, Marinković, Srdjan, Milanovic, Miljan, Lazovic, Mikan, Cuk, Vladica, Milutinović, Vladan, Djan, Vladimir, Trajkovic, Velicko, Lukic, Dejan, Radovanovic, Zoran, Zahorjanski, Sanja, Hing, Jun Xian, Teo, Nan Zun, Arbab, Hana, Dimatatac, Doris Mae, Chew, Min Hoe, Tan, Kiat Tee Benita, Ang, Wei-Wen, Chong, Yew-Lam, Tan, Ming Ngan Aloysius, Wong, Kar Yong, Gális, Branislav, Avsenak, 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Debo-Aina, Adeoye Oluwakanyinsola, Saha, Sunita, Campbell, William, Small, Sarah, Carlos, William, Chandla, Danny, Davis, Timothy, Dickson, Kathryn, Goodwin, Peter, Henning, Sarah, Kolokotroni, Maria, Mackay, Nicola, Stephens, Alastair, Surendran, Arthika, Ward, Thomas, Mena, Jimmy, Paul, Emila, Joshi, Anuja, McKay, Joanne, Weenink, Lotte, Cribb, Mark, Amin, Vishal, Dawson, Jonathon, Jangan, Akash, Mughal, Aamer, Olive, Rachel, Wall, Michael, Weedon, Stephanie, Kerr, Megan, Davison, Stephen, Doherty, Laura, Donoghue, Christopher, Faulkner, Alastair, MacInnes, Alasdair, McNicol, Rebecca, Rahman, Mohammad, Tiang, Kimberly, Foreman, Jennifer, McAllister, Ian, Collicott, Tom, Cullis, Paul, Holt, Phillip, Drake, Thomas, Durden, Andrew, Linder, Gustav, McGregor, Richard, Molyneux, Samuel, Norton, Joel, Robb, Lydia, Skipworth, Richard JE, Tambyraja, Andrew, Boyle, Connor, Hodge, Katherine, Paterson, Hugh, Smith, Scott, Vaughan-Shaw, Peter G, Benjamin, Miles, Rahimzadeh, Mana, Burden, Eleanor, 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- Abstract
Pulmonary complications are the most common cause of death after surgery. This study aimed to derive and externally validate a novel prognostic model that can be used before elective surgery to estimate the risk of postoperative pulmonary complications and to support resource allocation and prioritisation during pandemic recovery.
- Published
- 2024
- Full Text
- View/download PDF
50. Carbon vs. Titanium Nails in the Treatment of Impending and Pathological Fractures: A Literature Review.
- Author
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Pesare, Elisa, Meschini, Cesare, Caredda, Matteo, Messina, Federica, Rovere, Giuseppe, Solarino, Giuseppe, and Ziranu, Antonio
- Subjects
SPONTANEOUS fractures ,LITERATURE reviews ,TITANIUM ,INTRAMEDULLARY fracture fixation ,RADIATION doses ,NAIL diseases - Abstract
Background: Long bones are commonly affected by musculoskeletal tumors, but they also represent one of the most frequent locations for metastases. The treatment is based on pain management and the prevention or stabilization of pathological fractures by intramedullary nailing. While titanium nails are probably the most used, carbon-fiber-reinforced (CFR) nails have emerged as a new option for oncological patients. The aim of this review is to compare titanium and CFR nails according to current findings. Methods: Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) standards were followed: a total of 1004 articles were identified and 10 were included. Results: Traditionally, titanium implants are highly valued for their optimal biomechanical properties and ease of insertion, facilitated by their radiopacity. However, the use of titanium poses challenges in radiotherapy due to interference with radiation dosage and the creation of ferromagnetic artifacts. Conversely, CFR implants have emerged as a recommended option for intramedullary fixation, due to their biomechanical and structural properties and their benefits during radiotherapy and follow-up monitoring X-ray. Conclusions: CFR nailing represents a promising advancement in the surgical management of oncological patients with long bone metastases. However, further studies are needed to increase surgeons' confidence in their use. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
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