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5 results on '"Zieger, B. W."'

1. Age as a Risk Factor for Severe Manifestations and Fatal Outcome of Falciparum Malaria in European Patients: Observations from TropNetEurop and SIMPID Surveillance Data

Author

Mühlberger, N., Jelinek, T., Behrens, R. H., Gjørup, I., Coulaud, J. P., Clerinx, J., Puente, S., Burchard, G., Gascon, J., Grobusch, M. P., Weitzel, T., Zoller, T., Kollaritsch, H., Beran, J., Iversen, J., Hatz, C., Schmid, M. L., Björkman, A., Fleischer, K., Bisoffi, Z., Guggemos, W., Knobloch, J., Matteelli, A., Schulze, M. H., Laferl, H., Kapaun, A., McWhinney, P., Lopez-Velez, R., Fôtkenheuer, G., Kern, P., Zieger, B. W., Kotlowski, A., Fry, G., Cuadros, J., Myrvang, B., Mühlberger, N., Jelinek, T., Behrens, R. H., Gjørup, I., Coulaud, J. P., Clerinx, J., Puente, S., Burchard, G., Gascon, J., Grobusch, M. P., Weitzel, T., Zoller, T., Kollaritsch, H., Beran, J., Iversen, J., Hatz, C., Schmid, M. L., Björkman, A., Fleischer, K., Bisoffi, Z., Guggemos, W., Knobloch, J., Matteelli, A., Schulze, M. H., Laferl, H., Kapaun, A., McWhinney, P., Lopez-Velez, R., Fôtkenheuer, G., Kern, P., Zieger, B. W., Kotlowski, A., Fry, G., Cuadros, J., and Myrvang, B.

Abstract

Previous studies have indicated that age is a risk factor for severe falciparum malaria in nonimmune patients. The objectives of this study were to reevaluate previous findings with a larger sample and to find out how strongly clinical outcomes for elderly patients differ from those for younger patients. Results of adjusted analyses indicated that the risks of death due to falciparum malaria, of experiencing cerebral or severe disease in general, and of hospitalization increased significantly with each decade of life. The case-fatality rate was almost 6 times greater among elderly patients than among younger patients, and cerebral complications occurred 3 times more often among elderly patients. Antimalarial chemoprophylaxis was significantly associated with a lower case-fatality rate and a lower frequency of cerebral complications. Women were more susceptible to cerebral complications than were men. Our study provides evidence that falciparum malaria is more serious in older patients and demonstrates that clinical surveillance networks are capable of providing quality data for investigation of rare events or diseases

Published
2017

2. Age as a Risk Factor for Severe Manifestations and Fatal Outcome of Falciparum Malaria in European Patients: Observations from TropNetEurop and SIMPID Surveillance Data

Author

Mühlberger, N., Jelinek, T., Behrens, R. H., Gjørup, I., Coulaud, J. P., Clerinx, J., Puente, S., Burchard, G., Gascon, J., Grobusch, M. P., Weitzel, T., Zoller, T., Kollaritsch, H., Beran, J., Iversen, J., Hatz, C., Schmid, M. L., Björkman, A., Fleischer, K., Bisoffi, Z., Guggemos, W., Knobloch, J., Matteelli, A., Schulze, M. H., Laferl, H., Kapaun, A., McWhinney, P., Lopez-Velez, R., Fôtkenheuer, G., Kern, P., Zieger, B. W., Kotlowski, A., Fry, G., Cuadros, J., Myrvang, B., Mühlberger, N., Jelinek, T., Behrens, R. H., Gjørup, I., Coulaud, J. P., Clerinx, J., Puente, S., Burchard, G., Gascon, J., Grobusch, M. P., Weitzel, T., Zoller, T., Kollaritsch, H., Beran, J., Iversen, J., Hatz, C., Schmid, M. L., Björkman, A., Fleischer, K., Bisoffi, Z., Guggemos, W., Knobloch, J., Matteelli, A., Schulze, M. H., Laferl, H., Kapaun, A., McWhinney, P., Lopez-Velez, R., Fôtkenheuer, G., Kern, P., Zieger, B. W., Kotlowski, A., Fry, G., Cuadros, J., and Myrvang, B.

Abstract

Previous studies have indicated that age is a risk factor for severe falciparum malaria in nonimmune patients. The objectives of this study were to reevaluate previous findings with a larger sample and to find out how strongly clinical outcomes for elderly patients differ from those for younger patients. Results of adjusted analyses indicated that the risks of death due to falciparum malaria, of experiencing cerebral or severe disease in general, and of hospitalization increased significantly with each decade of life. The case-fatality rate was almost 6 times greater among elderly patients than among younger patients, and cerebral complications occurred 3 times more often among elderly patients. Antimalarial chemoprophylaxis was significantly associated with a lower case-fatality rate and a lower frequency of cerebral complications. Women were more susceptible to cerebral complications than were men. Our study provides evidence that falciparum malaria is more serious in older patients and demonstrates that clinical surveillance networks are capable of providing quality data for investigation of rare events or diseases

4. Age as a risk factor for severe manifestations and fatal outcome of falciparum malaria in European patients: observations from TropNetEurop and SIMPID Surveillance Data.

Author

Mühlberger N, Jelinek T, Behrens RH, Gjørup I, Coulaud JP, Clerinx J, Puente S, Burchard G, Gascon J, Grobusch MP, Weitzel T, Zoller T, Kollaritsch H, Beran J, Iversen J, Hatz C, Schmid ML, Björkman A, Fleischer K, Bisoffi Z, Guggemos W, Knobloch J, Matteelli A, Schulze MH, Laferl H, Kapaun A, McWhinney P, Lopez-Velez R, Fätkenheuer G, Kern P, Zieger BW, Kotlowski A, Fry G, Cuadros J, and Myrvang B

Subjects
Age Factors, Aged, Animals, Europe epidemiology, Fatal Outcome, Female, Humans, Malaria, Falciparum epidemiology, Male, Malaria, Falciparum mortality, Risk Factors
Abstract

Previous studies have indicated that age is a risk factor for severe falciparum malaria in nonimmune patients. The objectives of this study were to reevaluate previous findings with a larger sample and to find out how strongly clinical outcomes for elderly patients differ from those for younger patients. Results of adjusted analyses indicated that the risks of death due to falciparum malaria, of experiencing cerebral or severe disease in general, and of hospitalization increased significantly with each decade of life. The case-fatality rate was almost 6 times greater among elderly patients than among younger patients, and cerebral complications occurred 3 times more often among elderly patients. Antimalarial chemoprophylaxis was significantly associated with a lower case-fatality rate and a lower frequency of cerebral complications. Women were more susceptible to cerebral complications than were men. Our study provides evidence that falciparum malaria is more serious in older patients and demonstrates that clinical surveillance networks are capable of providing quality data for investigation of rare events or diseases.

Published
2003
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5. [Diagnosis of urogenital schistosomiasis--personal studies in 107 patients].

Author

Micklisch F and Zieger BW

Subjects
Calcinosis pathology, Cystoscopy, Humans, Schistosomiasis haematobia complications, Urinary Bladder pathology, Urography, Schistosomiasis haematobia pathology
Abstract

The endoscopic and roentgenological findings of foreign patients who were hospitalized in our institution for a urogenital bilharziosis are demonstrated and classified according to its diagnostic valency. It is referred to the urgency of an early diagnosing and performance of therapy.

Published
1987

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