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3. Adverse Cardiac Manifestations Following Dextropropoxyphene Overdose - Can Naloxone Be Helpful

Author

UCL - Cliniques universitaires Saint-Luc, UCL, Hantson, Philippe, Evenepoel, M., Ziade, D., Hassoun, A., Mahieu, P., UCL - Cliniques universitaires Saint-Luc, UCL, Hantson, Philippe, Evenepoel, M., Ziade, D., Hassoun, A., and Mahieu, P.

Abstract

Dextropropoxyphene overdose may be complicated by serious cardiovascular manifestations, including conduction abnormalities and collapse. We report two patients in wham cardiac toxicity developed. Cardiovascular depression seemed to be improved after naloxone infusion in these two cases. Possible mechanisms are briefly discussed.

Published
1995

4. Adverse Cardiac Manifestations Following Dextropropoxyphene Overdose: Can Naloxone Be Helpful?

Author

Hantson, P., Evenepoel, M., Ziade, D., Hassoun, A., and Mahieu, P.

Abstract

Dextropropoxyphene overdose may be complicated by serious cardiovascular manifestations, including conduction abnormalities and collapse. We report two patients in whom cardiac toxicity developed. Cardiovascular depression seemed to be improved after naloxone infusion in these two cases. Possible mechanisms are briefly discussed. [Hantson P, Evenepoel M, Ziade D, Hassoun A, Mahieu P: Adverse cardiac manifestations following dextropropoxyphene overdose: Can naloxone be helpful? Ann Emerg Med February 1995;25:263-266.]

Published
1995
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5. Bilateral pneumothorax and pneumomediastinum after treatment with continuous positive airway pressure after orthognathic surgery.

Author

Chebel NA, Ziade D, and Achkouty R

Subjects
Adult, Female, Follow-Up Studies, Humans, Hypoxia etiology, Osteotomy, Le Fort adverse effects, Postoperative Complications, Pulmonary Atelectasis etiology, Subcutaneous Emphysema etiology, Continuous Positive Airway Pressure adverse effects, Mediastinal Emphysema etiology, Orthognathic Surgical Procedures adverse effects, Pneumothorax etiology
Abstract

We describe a 25-year-old woman who developed hypoxaemia secondary to pulmonary atelectasis after orthognathic surgery. Treatment with continuous positive airway pressure (CPAP) through a face-mask postoperatively was complicated by subcutaneous emphysema, pneumomediastinum, and bilateral pneumothoraces. CPAP has been advocated for the treatment of postoperative hypoxaemia, but when used in the presence of facial trauma or when the oral mucosa has been disrupted it can cause subcutaneous emphysema. We suggest that it is not used after orthognathic surgery., (Copyright 2009 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.)

Published
2010
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6. Cardiac conduction abnormalities during carbamazepine therapy for neuralgia following Guillain-Barré syndrome.

Author

Hantson P, Ilunga K, Martin N, Ziade D, Evenepoel M, Cojocaru M, and Mahieu P

Subjects
Heart Block therapy, Humans, Male, Middle Aged, Pacemaker, Artificial, Carbamazepine adverse effects, Heart Arrest chemically induced, Heart Block chemically induced, Polyradiculoneuropathy drug therapy
Abstract

A 61-year-old man without previous medical history was admitted for Guillain-Barré syndrome (GBS). Carbamazepine was prescribed on day 72 for dysesthesia occurring at the time of recovery. Subsequently, severe cardiac conduction disturbances (asystole, atrioventricular block) were observed and a permanent pacemaker had to be inserted. The possible relationship between carbamazepine therapy and cardiac side effects is discussed in this condition, as GBS itself is often complicated by cardiac arrhythmias.

Published
1993

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