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8. Light-Sheet Skew Ray-Based Microbubble Chemical Sensor for Pb 2+ Measurements.

Author

Zhuang, Tingting, Xu, Lukui, Khalid, Mamoona, Wu, Xuan, Du, Linqiao, Shahnia, Soroush, Codemard, Christophe A., Bai, Zhiyong, Wang, Ying, Liu, Shen, Chen, George Y., and Wang, Yiping

Subjects
*OPTICAL fiber detectors, *CHEMICAL detectors, *LEAD, *GOLD nanoparticles, *OXALIC acid, *SURFACE plasmon resonance
Abstract

A multimode fiber-based sensor is proposed and demonstrated for the detection of lead traces in contaminated water. The sensing mechanism involves using a light sheet to excite a specific group of skew rays that optimizes light absorption. The sensing region features an inline microbubble structure that funnels the skew rays into a tight ring, thereby intensifying the evanescent field. The sensitivity is further refined by incorporating gold nanoparticles, which amplify the evanescent field strength through localized surface plasmon resonance. The gold nanoparticles are functionalized with oxalic acid to improve specificity for lead ion detection. Experiment results demonstrated the significantly enhanced absorption sensitivity of the proposed sensing method for large center offsets, achieving a detection limit of 0.1305 ng/mL (the World Health Organization safety limit is 10 ng/mL) for concentrations ranging from 0.1 to 10 ng/mL. [ABSTRACT FROM AUTHOR]

Published
2024
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22. E089 Effect of secukinumab on radiographic progression and inflammation in sacroiliac joints and spine in patients with non-radiographic axial spondyloarthritis: 2-year imaging outcomes from a Phase III randomised trial

Author

Marzo-Ortega, Helena, primary, Braun, Juergen, additional, Blanco, Ricardo, additional, Gensler, Lianne S, additional, van den Bosch, Filip, additional, Hall, Stephen, additional, Kameda, Hideto, additional, Poddubnyy, Denis, additional, van de Sande, Marleen G H, additional, van der Heidje, Désirée, additional, Zhuang, Tingting, additional, Stefanska, Anna, additional, Readie, Aimee, additional, Richards, Hanno, additional, and Deodhar, Atul, additional

Published
2023
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23. Supplementary Data from A Phase III Multicenter Randomized Clinical Trial of 60 Gy versus 50 Gy Radiation Dose in Concurrent Chemoradiotherapy for Inoperable Esophageal Squamous Cell Carcinoma

Author

Xu, Yujin, primary, Dong, Baiqiang, primary, Zhu, Weiguo, primary, Li, Jiancheng, primary, Huang, Rong, primary, Sun, Zongwen, primary, Yang, Xinmei, primary, Liu, Liping, primary, He, Han, primary, Liao, Zhongxing, primary, Guan, Ni, primary, Kong, Yue, primary, Wang, Wanwei, primary, Chen, Jianxiang, primary, He, Huijuan, primary, Qiu, Guoqin, primary, Zeng, Ming, primary, Pu, Juan, primary, Hu, Wangyuan, primary, Bao, Yong, primary, Liu, Zhigang, primary, Ma, Jun, primary, Jiang, Hao, primary, Du, Xianghui, primary, Hu, Jin, primary, Zhuang, Tingting, primary, Cai, Jing, primary, Huang, Jin, primary, Tao, Hua, primary, Liu, Yuan, primary, Liang, Xiaodong, primary, Zhou, Juying, primary, Tao, Guangzhou, primary, Zheng, Xiao, primary, and Chen, Ming, primary

Published
2023
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24. Supplementary Table from A Phase III Multicenter Randomized Clinical Trial of 60 Gy versus 50 Gy Radiation Dose in Concurrent Chemoradiotherapy for Inoperable Esophageal Squamous Cell Carcinoma

Author

Xu, Yujin, primary, Dong, Baiqiang, primary, Zhu, Weiguo, primary, Li, Jiancheng, primary, Huang, Rong, primary, Sun, Zongwen, primary, Yang, Xinmei, primary, Liu, Liping, primary, He, Han, primary, Liao, Zhongxing, primary, Guan, Ni, primary, Kong, Yue, primary, Wang, Wanwei, primary, Chen, Jianxiang, primary, He, Huijuan, primary, Qiu, Guoqin, primary, Zeng, Ming, primary, Pu, Juan, primary, Hu, Wangyuan, primary, Bao, Yong, primary, Liu, Zhigang, primary, Ma, Jun, primary, Jiang, Hao, primary, Du, Xianghui, primary, Hu, Jin, primary, Zhuang, Tingting, primary, Cai, Jing, primary, Huang, Jin, primary, Tao, Hua, primary, Liu, Yuan, primary, Liang, Xiaodong, primary, Zhou, Juying, primary, Tao, Guangzhou, primary, Zheng, Xiao, primary, and Chen, Ming, primary

Published
2023
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25. Supplementary Figure from A Phase III Multicenter Randomized Clinical Trial of 60 Gy versus 50 Gy Radiation Dose in Concurrent Chemoradiotherapy for Inoperable Esophageal Squamous Cell Carcinoma

Author

Xu, Yujin, primary, Dong, Baiqiang, primary, Zhu, Weiguo, primary, Li, Jiancheng, primary, Huang, Rong, primary, Sun, Zongwen, primary, Yang, Xinmei, primary, Liu, Liping, primary, He, Han, primary, Liao, Zhongxing, primary, Guan, Ni, primary, Kong, Yue, primary, Wang, Wanwei, primary, Chen, Jianxiang, primary, He, Huijuan, primary, Qiu, Guoqin, primary, Zeng, Ming, primary, Pu, Juan, primary, Hu, Wangyuan, primary, Bao, Yong, primary, Liu, Zhigang, primary, Ma, Jun, primary, Jiang, Hao, primary, Du, Xianghui, primary, Hu, Jin, primary, Zhuang, Tingting, primary, Cai, Jing, primary, Huang, Jin, primary, Tao, Hua, primary, Liu, Yuan, primary, Liang, Xiaodong, primary, Zhou, Juying, primary, Tao, Guangzhou, primary, Zheng, Xiao, primary, and Chen, Ming, primary

Published
2023
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29. Additional file 1 of Two-year imaging outcomes from a phase 3 randomized trial of secukinumab in patients with non-radiographic axial spondyloarthritis

Author

Braun, Juergen, Blanco, Ricardo, Marzo-Ortega, Helena, Gensler, Lianne S., Van den Bosch, Filip, Hall, Stephen, Kameda, Hideto, Poddubnyy, Denis, van de Sande, Marleen, van der Heijde, Désirée, Zhuang, Tingting, Stefanska, Anna, Readie, Aimee, Richards, Hanno B., and Deodhar, Atul

Abstract

Additional file 1: Fig. S1. Study Design. Fig. S2. Mean change in SI joint bone marrow edema score by MRI in the overall population and in patients with baseline score >2 through week 104 (in patients with images available at all 4 time points). Table S1. Syndesmophyte status at screening by mNY status at screening based on single reader assessment and two reader agreement.

Published
2023
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40. A Phase III Multicenter Randomized Clinical Trial of 60 Gy versus 50 Gy Radiation Dose in Concurrent Chemoradiotherapy for Inoperable Esophageal Squamous Cell Carcinoma

Author

Xu, Yujin, primary, Dong, Baiqiang, additional, Zhu, Weiguo, additional, Li, Jiancheng, additional, Huang, Rong, additional, Sun, Zongwen, additional, Yang, Xinmei, additional, Liu, Liping, additional, He, Han, additional, Liao, Zhongxing, additional, Guan, Ni, additional, Kong, Yue, additional, Wang, Wanwei, additional, Chen, Jianxiang, additional, He, Huijuan, additional, Qiu, Guoqin, additional, Zeng, Ming, additional, Pu, Juan, additional, Hu, Wangyuan, additional, Bao, Yong, additional, Liu, Zhigang, additional, Ma, Jun, additional, Jiang, Hao, additional, Du, Xianghui, additional, Hu, Jin, additional, Zhuang, Tingting, additional, Cai, Jing, additional, Huang, Jin, additional, Tao, Hua, additional, Liu, Yuan, additional, Liang, Xiaodong, additional, Zhou, Juying, additional, Tao, Guangzhou, additional, Zheng, Xiao, additional, and Chen, Ming, additional

Published
2022
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44. Study on the high‐temperature damping properties of silicone rubber modified by boron‐terminated polysiloxane.

Author

Cui, Hongwei, Jing, Qian, Li, Dongwei, Zhuang, Tingting, Gao, Yixing, and Ran, Xianghai

Subjects
SILICONE rubber, FOURIER transform infrared spectroscopy, DYNAMIC mechanical analysis, GEL permeation chromatography, NUCLEAR magnetic resonance, COORDINATE covalent bond
Abstract

Rubber damping materials have important applications in modern industrial systems. However, their damping temperature range is low, which is not suitable for the damping demand under high temperature conditions. At present, there is very little research on the damping performance of rubber under high temperature conditions. Silicone rubber has excellent high temperature resistance but poor damping in its application temperature range. In this study, a boron‐terminated polysiloxane (PBS) was prepared by modifying hydroxy‐terminated polydimethylsiloxane (PDMS‐OH) with boric acid (BA). The molecular structure of PBS was confirmed by Fourier transform infrared spectroscopy (FTIR), nuclear magnetic resonance (NMR) and gel permeation chromatography (GPC) analysis. Rheology measurements revealed that PBS was a "shear hardening" material. Then, the silicone rubber was modified with PBS. With the introduction of boron atoms, boron and oxygen dative bonds with dynamic properties could be formed inside the silicone rubber, which played an energy dissipation role in the process of association/dissociation. Dynamic mechanical analysis (DMA) showed that the loss factor (tan δ) of modified silicone rubber was greater than 0.3 in the temperature range of 81.5°C–250°C, which was higher than the loss temperature range of conventional damping rubber. The cyclic stress–strain test also showed that the modified silicone rubber still had high dissipation coefficient (DE) at high temperature. Therefore, the PBS‐modified silicone rubber prepared by this method achieved excellent damping performance under high temperature conditions. [ABSTRACT FROM AUTHOR]

Published
2023
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47. Nano-hybrid luminophores of Ti3C2TX quantum dots-gold nanoparticles based on in situ generation for sensitive electrochemiluminescence biosensing.

Author

Zhang, Huixin, Wang, Lun, Zhuang, Tingting, Wei, Zhihao, Xia, Jianfei, and Wang, Zonghua

Subjects
LUMINOPHORES, ELECTROCHEMILUMINESCENCE, MOLECULAR size, QUANTUM dots, DETECTION limit, CHARGE transfer
Abstract

Nanomaterial-derived quantum dots (QDs) are excellent electrochemiluminescence (ECL) luminophores and play an important role in optical sensing due to their excellent water solubility, good biocompatibility and tunable molecular size. In this work, a novel strategy was designed to form nano-hybrid Ti3C2 QDs-AuNPs in situ as a luminophore based on the unique reducibility of Ti3C2 QDs, which showed remarkable and stable ECL performance. Here, AuNPs were formed in situ without the addition of reducing agents and stabilizers, leading to threefold enhancement of the ECL signal of Ti3C2 QDs due to their excellent charge transfer capability. Meanwhile, Ti3C2 QDs-AuNPs with abundant Ti atoms also acted as recognition units. Through skillful combination with hybridization chain reaction (HCR) to expose more phosphate, an ECL platform was constructed to detect polynucleotide kinase (PNK) with good specificity and sensitivity. A lower limit of detection limit of 2.7×10−5 U mL−1 was achieved, with a wide linear relationship ranging from 0.0001 to 10 U mL−1. This novel strategy provides a guide for the application of nano-hybrid Ti3C2 QDs-AuNPs as a luminophore in the field of ECL bioanalysis. Novel in situ-formed nano-hybrid Ti3C2 QDs-AuNPs were prepared as a luminophore, with threefold enhancement of the ECL signal of Ti3C2 QDs. [ABSTRACT FROM AUTHOR]

Published
2022
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