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Novel methods of inverse reconstruction of environmental loads and virtual model test for hybrid model test are proposed. The environmental loads are extracted from the physical truncated model test, considering the nonlinear effects such as coupling effect among the six-degrees-of-freedom (6 DOF) motions and wave slamming, and viscous force of the fluid. The loads can be further applied to the numerical model in virtual wave basin to conduct virtual model test with truncated and full-depth mooring system. Wave basin tests under combined wave, wind, and current condition are conducted to validate the proposed methods, and the results show that the environmental loads can be accurately reconstructed from the physical model tests.

Provincial-level natural resources survey and monitoring play a crucial role in the national natural resources survey and monitoring system. Constructing a provincial-level system is essential for effectively implementing the national survey and monitoring work. However, the construction of such a system in Guangdong Province, a typical tropical and subtropical coastal region with diverse natural resources and distinctive geographical characteristics, presents significant challenges. This study focuses on addressing several problems encountered in Guangdong Province, including the lack of optical image data due to the region's cloudy and rainy climate, fragmented monitoring patches resulting from complex terrain and landforms, rapid changes in the surface caused by high-intensity human activities, and the difficulty in managing a wide range of monitoring objects. By clarifying the goals of natural resources survey and monitoring, this study systematically reviews the status and practical needs of a provincial-level survey and monitoring work and summarizes the key issues in the construction of the survey and monitoring system. This study proposes an overall construction plan for a provincial-level system that includes establishing a unified basic platform, which aids in implementing a fast and coordinated monitoring mode, developing flexible and efficient application services, and strengthening intensive and refined support environments. It also analyzes critical challenges, such as organizational model restructuring, accurate object recognition, and technological integration. Finally, this study presents a path to achieve the provincial-level natural resources survey and monitoring, focusing on object-based businesses, information implementation, technological intelligence, targeted evaluation, and service knowledge. Regarding investigation targets, this study emphasizes adopting a "business-oriented" approach, enhancing the alignment of investigation and monitoring with precise business strategies and facilitating bidirectional feedback. Regarding organizational implementation, this study emphasizes strengthening support through "information technology," establishing provincial-level coordination and a municipal and county-level division of labor model, commonly referred to as the "general-subordinate-general" organizational structure. Regarding monitoring technology, this study emphasizes adopting an "intelligence-led" approach; it is primarily centering on pivotal technological research related to collaborative perception, intelligent processing, integrated management, and intelligent services. Regarding analysis and evaluation, this study emphasizes a "target-oriented" approach, centered around supporting economic and social development and optimizing natural resource management through comprehensive analysis and evaluation. Regarding application services, this study emphasizes delivering "knowledge-based" services and exploring the development of a model that encompasses the knowledge ontology of natural resource investigation and monitoring. This study promotes the orderly construction of a survey and monitoring system in Guangdong Province, provides a scientific basis for provincial-level natural resource surveys and monitoring work and serves as a reference for the construction of survey and monitoring systems in other regions.

Since the reform and opening up, China has achieved great progress in industrialization and urbanization. However, due to the long-term implementation of the economic development model of "emphasizing cities over township" and the urban-rural dual system, the gap between urban and rural development is constantly increasing, and the problems of land resource allocation and contradiction between man and land in rural areas have gradually emerged. Rural homestead is the main place where farmers live, with unique land use characteristics. The information such as the structure and utilization status of houses on it can clearly reflect the local rural economic situation and homestead problems. Therefore, understanding the characteristics and differences of rural homestead housing is of great significance to understand and grasp the situation and problems of rural development and promote the implementation of rural revitalization strategy. Based on the rural cadastral survey data of Guangdong Province and combined with GIS spatial analysis method, this paper analyzes the characteristics of rural homestead housing. The results show that: (1) The rural housing in the study area is relatively low, mainly with one floor, supplemented by two and three floors, mainly brick and mixed structure, supplemented by concrete structure, and there is a certain correlation between the number of floors and the spatial distribution of the structure. Among them, the proportions of one storey house, brick structure and mixed structure house are 59.42%, 37.71% and 42.60% respectively. (2) There are obvious regional differences in the number of floors and structural spatial distribution of rural homestead housing in the study area. Low-rise, brick and mixed structure houses are mainly distributed in remote areas such as northern and western Guangdong, and high-rise and concrete structure houses are mostly concentrated in the Pearl River Delta. (3) The vacancy and idleness of rural homestead housing in the study area are common. The average vacancy rate and idle rate are 6.75% and 5.66% respectively, and the rate of one househould with multiple houses reaches 23.88%. The phenomenon of rural hollowing is obvious, and 50.87% of the villages in districts and counties are above the moderate hollowing, mainly distributed in the fringe area of the Pearl River Delta and Meizhou in northern Guangdong. At the same time, there is a certain phenomenon that the average household homestead area exceeds the standard. (4) The characteristics of rural housing utilization in Guangdong Province are affected by factors such as policies, economy, transportation, physical geographical condition and local customs. And the influencing factors in different regions are different, such as the special folk customs have a greater impact on rural housing in eastern Guangdong, and the economic situations and urban siphon have a greater impact on the characteristics of rural housing in the edge of the Pearl River Delta. There are obvious spatial differences in the utilization of rural homestead housing in Guangdong Province, and there are many idle homestead resources. There is great potential for the optimization and adjustment of rural construction land for rural revitalization.

Bioceramics are vital for treating bone defects, and bioactive glasses (exemplified by 45S5) and calcium phosphate ceramics (CaPs, exemplified by tricalcium phosphate [β‐TCP]) are extensively explored. β‐TCP exhibits superior biocompatibility, degradability, and osteoconductive properties than 45S5; however, it lacks bioactivity, such as mineralization capability. To harness the synergies of both, four 3D printing bioceramic scaffolds: 45S5, 70% 45S5 + 30% TCP, 30% 45S5 + 70% TCP, and TCP, are manufactured. Furthermore, the investigation elucidates the correlation between their in situ mineralization capabilities and the intracellular calcium oscillations within macrophages and determines how they impact macrophage phenotypic transitions. Notably, during bioceramic degradation, there is an initial rise followed by a decline in calcium ion concentration, which results in intracellular calcium ion oscillations within macrophages. In the 70% 45S5 + 30% TCP group, early release of calcium ions promotes M1 macrophage polarization. Subsequently, rapid in situ mineralization causes a decrease in extracellular calcium ions, thus accelerating the transition of M1 to M2 macrophages and facilitating bone repair. The present study reveals a novel mechanism through which bioceramics modulate macrophage polarization, offers new insights into the initial foreign body response to bioceramics and presents a perspective on expeditious progression toward tissue repair. [ABSTRACT FROM AUTHOR]