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461 results on '"Zhu, Yuelin"'

11. Placental development and preeclampsia

Author

Zhu Yuelin, Li Qianqian, Wang Yanling, and Shao Xuan

Subjects
human placenta, functional units of placenta, trophoblast, multiple cell-cell interaction, preeclampsia, Medicine, Biotechnology, TP248.13-248.65
Abstract

Serving as the interface between the fetal and maternal environment during gestation, the placenta plays critical roles in the protection of the developing fetus and the maintenance of pregnancy. The placenta is responsible for blood perfusion and maternal-fetal material exchange, immune tolerance, and the regulation of pregnancy adaptation. Defects in placental development and functional maintenance are in tight association with adverse pregnancy outcomes such as preeclampsia. In this article, we reviewed recent advances on human trophoblast cell differentiation and the construction of placental functional units and discuss the pathogenic factors that may contribute to the occurrence of preeclampsia.

Published
2022
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12. The DNA methyltransferase inhibitor 5-aza-4’-thio-2’-deoxycytidine induces C>G transversions and acute lymphoid leukemia development

Author

Bertoli, Ryan M., primary, Chung, Yang Jo, additional, Difilippantonio, Michael J., additional, Wokasch, Anthony, additional, Marasco, Madison R.B., additional, Klimaszewski, Haley, additional, Gammell, Susannah, additional, Zhu, Yuelin J., additional, Walker, Robert L., additional, Cao, Dengchao, additional, Khanna, Ajay, additional, Walter, Matthew J., additional, Doroshow, James H., additional, Meltzer, Paul S., additional, and Aplan, Peter D., additional

Published
2024
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17. Outcomes of Children and Adolescents with Advanced Hereditary Medullary Thyroid Carcinoma Treated with Vandetanib.

Author

Kraft, Ira, Akshintala, Srivandana, Zhu, Yuelin, Lei, Haiyan, Derse-Anthony, Claudia, Dombi, Eva, Steinberg, Seth, Lodish, Maya, Waguespack, Steven, Kapustina, Oxana, Fox, Elizabeth, Balis, Frank, Merino, Maria, Meltzer, Paul, Glod, John, Shern, Jack, and Widemann, Brigitte

Subjects
Adolescent, Carcinoma, Medullary, Child, Disease Progression, Disease-Free Survival, Female, Germ-Line Mutation, Humans, Male, Multiple Endocrine Neoplasia Type 2a, Outcome Assessment, Health Care, Piperidines, Protein Kinase Inhibitors, Quinazolines, Thyroid Neoplasms
Abstract

Purpose: Vandetanib is well-tolerated in patients with advanced medullary thyroid carcinoma (MTC). Long-term outcomes and mechanisms of MTC progression have not been reported previously.Experimental Design: We monitored toxicities and disease status in patients taking vandetanib for hereditary, advanced MTC. Tumor samples were analyzed for molecular mechanisms of disease progression.Results: Seventeen patients [8 male, age 13 (9-17)* years] enrolled; 16 had a RET p.Met918Thr germline mutation. The duration of vandetanib therapy was 6.1 (0.1-9.7+)* years with treatment ongoing in 9 patients. Best response was partial response in 10, stable disease in 6, and progressive disease in one patient. Duration of response was 7.4 (0.6-8.7+)* and 4.9 (0.6-7.8+)* years in patients with PR and SD, respectively. Six patients died 2.0 (0.4-5.7)* years after progression. Median progression-free survival (PFS) was 6.7 years [95% confidence interval (CI): 2.3 years-undefined] and 5-year overall survival (OS) was 88.2% (95% CI: 60.6%-96.9%). Of 16 patients with a RET p.Met918Thr mutation, progression-free survival was 6.7 years (95% CI: 3.1-undefined) and 5-year overall survival was 93.8% (95% CI: 63.2%-99.1%). No patients terminated treatment because of toxicity. DNA sequencing of tissue samples (n = 11) identified an increase in copy number alterations across the genome as a potential mechanism of drug resistance [*median (range)].Conclusions: This study demonstrates that vandetanib is safe and results in sustained responses in children and adolescents with hereditary MTC. Our preliminary molecular data suggest that an increase in copy number abnormalities may be associated with tumor progression in hereditary MTC patients treated with vandetanib. Clin Cancer Res; 24(4); 753-65. ©2017 AACR.

Published
2018

18. Harnessing the power of microbes: Enhancing soybean growth in an acidic soil through AMF inoculation rather than P-fertilization

Author

Wen, Zhongling, primary, Yang, Minkai, additional, Fazal, Aliya, additional, Han, Hongwei, additional, Lin, Hongyan, additional, Yin, Tongming, additional, Zhu, Yuelin, additional, Yang, Shouping, additional, Niu, Kechang, additional, Sun, Shucun, additional, Qi, Jinliang, additional, Lu, Guihua, additional, and Yang, Yonghua, additional

Published
2024
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23. Author Correction: Recurrent PTPRT/JAK2 mutations in lung adenocarcinoma among African Americans

Author

Mitchell, Khadijah A., Nichols, Noah, Tang, Wei, Walling, Jennifer, Stevenson, Holly, Pineda, Marbin, Stefanescu, Roxana, Edelman, Daniel C., Girvin, Andrew T., Zingone, Adriana, Sinha, Sanju, Bowman, Elise, Rossi, Emily L., Arauz, Rony F., Zhu, Yuelin Jack, Lack, Justin, Weingartner, Elizabeth, Waterfall, Joshua J., Pine, Sharon R., Simmons, John, Meltzer, Paul, and Ryan, Bríd M.

Published
2020
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24. Recurrent PTPRT/JAK2 mutations in lung adenocarcinoma among African Americans

Author

Mitchell, Khadijah A., Nichols, Noah, Tang, Wei, Walling, Jennifer, Stevenson, Holly, Pineda, Marbin, Stefanescu, Roxana, Edelman, Daniel C., Girvin, Andrew T., Zingone, Adriana, Sinha, Sanju, Bowman, Elise, Rossi, Emily L., Arauz, Rony F., Jack Zhu, Yuelin, Lack, Justin, Weingartner, Elizabeth, Waterfall, Joshua J., Pine, Sharon R., Simmons, John, Meltzer, Paul, and Ryan, Bríd M.

Published
2019
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26. Supplementary Figure 1 from Succinate Dehydrogenase Mutation Underlies Global Epigenomic Divergence in Gastrointestinal Stromal Tumor

Author

Killian, J. Keith, primary, Kim, Su Young, primary, Miettinen, Markku, primary, Smith, Carly, primary, Merino, Maria, primary, Tsokos, Maria, primary, Quezado, Martha, primary, Smith, William I., primary, Jahromi, Mona S., primary, Xekouki, Paraskevi, primary, Szarek, Eva, primary, Walker, Robert L., primary, Lasota, Jerzy, primary, Raffeld, Mark, primary, Klotzle, Brandy, primary, Wang, Zengfeng, primary, Jones, Laura, primary, Zhu, Yuelin, primary, Wang, Yonghong, primary, Waterfall, Joshua J., primary, O'Sullivan, Maureen J., primary, Bibikova, Marina, primary, Pacak, Karel, primary, Stratakis, Constantine, primary, Janeway, Katherine A., primary, Schiffman, Joshua D., primary, Fan, Jian-Bing, primary, Helman, Lee, primary, and Meltzer, Paul S., primary

Published
2023
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27. Data from Succinate Dehydrogenase Mutation Underlies Global Epigenomic Divergence in Gastrointestinal Stromal Tumor

Author

Killian, J. Keith, primary, Kim, Su Young, primary, Miettinen, Markku, primary, Smith, Carly, primary, Merino, Maria, primary, Tsokos, Maria, primary, Quezado, Martha, primary, Smith, William I., primary, Jahromi, Mona S., primary, Xekouki, Paraskevi, primary, Szarek, Eva, primary, Walker, Robert L., primary, Lasota, Jerzy, primary, Raffeld, Mark, primary, Klotzle, Brandy, primary, Wang, Zengfeng, primary, Jones, Laura, primary, Zhu, Yuelin, primary, Wang, Yonghong, primary, Waterfall, Joshua J., primary, O'Sullivan, Maureen J., primary, Bibikova, Marina, primary, Pacak, Karel, primary, Stratakis, Constantine, primary, Janeway, Katherine A., primary, Schiffman, Joshua D., primary, Fan, Jian-Bing, primary, Helman, Lee, primary, and Meltzer, Paul S., primary

Published
2023
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28. Supplementary Table 2 from Succinate Dehydrogenase Mutation Underlies Global Epigenomic Divergence in Gastrointestinal Stromal Tumor

Author

Killian, J. Keith, primary, Kim, Su Young, primary, Miettinen, Markku, primary, Smith, Carly, primary, Merino, Maria, primary, Tsokos, Maria, primary, Quezado, Martha, primary, Smith, William I., primary, Jahromi, Mona S., primary, Xekouki, Paraskevi, primary, Szarek, Eva, primary, Walker, Robert L., primary, Lasota, Jerzy, primary, Raffeld, Mark, primary, Klotzle, Brandy, primary, Wang, Zengfeng, primary, Jones, Laura, primary, Zhu, Yuelin, primary, Wang, Yonghong, primary, Waterfall, Joshua J., primary, O'Sullivan, Maureen J., primary, Bibikova, Marina, primary, Pacak, Karel, primary, Stratakis, Constantine, primary, Janeway, Katherine A., primary, Schiffman, Joshua D., primary, Fan, Jian-Bing, primary, Helman, Lee, primary, and Meltzer, Paul S., primary

Published
2023
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29. Supplementary Table 1 from Succinate Dehydrogenase Mutation Underlies Global Epigenomic Divergence in Gastrointestinal Stromal Tumor

Author

Killian, J. Keith, primary, Kim, Su Young, primary, Miettinen, Markku, primary, Smith, Carly, primary, Merino, Maria, primary, Tsokos, Maria, primary, Quezado, Martha, primary, Smith, William I., primary, Jahromi, Mona S., primary, Xekouki, Paraskevi, primary, Szarek, Eva, primary, Walker, Robert L., primary, Lasota, Jerzy, primary, Raffeld, Mark, primary, Klotzle, Brandy, primary, Wang, Zengfeng, primary, Jones, Laura, primary, Zhu, Yuelin, primary, Wang, Yonghong, primary, Waterfall, Joshua J., primary, O'Sullivan, Maureen J., primary, Bibikova, Marina, primary, Pacak, Karel, primary, Stratakis, Constantine, primary, Janeway, Katherine A., primary, Schiffman, Joshua D., primary, Fan, Jian-Bing, primary, Helman, Lee, primary, and Meltzer, Paul S., primary

Published
2023
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32. Supplementary Table S6 from Mutant Idh2 Cooperates with a NUP98-HOXD13 Fusion to Induce Early Immature Thymocyte Precursor ALL

Author

Goldberg, Liat, primary, Negi, Vijay, primary, Chung, Yang Jo, primary, Onozawa, Masahiro, primary, Zhu, Yuelin J., primary, Walker, Robert L., primary, Pierce, Rachel, primary, Patel, Daxesh P., primary, Krausz, Kristopher W., primary, Gonzalez, Frank J., primary, Goodell, Margaret A., primary, Rodriguez, Benjamin A.T., primary, Meltzer, Paul S., primary, and Aplan, Peter D., primary

Published
2023
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33. Supplementary Figure 2 from Polycomb Repressor Complex-2 Is a Novel Target for Mesothelioma Therapy

Author

Kemp, Clinton D., primary, Rao, Mahadev, primary, Xi, Sichuan, primary, Inchauste, Suzanne, primary, Mani, Haresh, primary, Fetsch, Patricia, primary, Filie, Armando, primary, Zhang, Mary, primary, Hong, Julie A., primary, Walker, Robert L., primary, Zhu, Yuelin J., primary, Ripley, R. Taylor, primary, Mathur, Aarti, primary, Liu, Fang, primary, Yang, Maocheng, primary, Meltzer, Paul A., primary, Marquez, Victor E., primary, De Rienzo, Assunta, primary, Bueno, Raphael, primary, and Schrump, David S., primary

Published
2023
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34. Supplementary Table 6 from Polycomb Repressor Complex-2 Is a Novel Target for Mesothelioma Therapy

Author

Kemp, Clinton D., primary, Rao, Mahadev, primary, Xi, Sichuan, primary, Inchauste, Suzanne, primary, Mani, Haresh, primary, Fetsch, Patricia, primary, Filie, Armando, primary, Zhang, Mary, primary, Hong, Julie A., primary, Walker, Robert L., primary, Zhu, Yuelin J., primary, Ripley, R. Taylor, primary, Mathur, Aarti, primary, Liu, Fang, primary, Yang, Maocheng, primary, Meltzer, Paul A., primary, Marquez, Victor E., primary, De Rienzo, Assunta, primary, Bueno, Raphael, primary, and Schrump, David S., primary

Published
2023
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35. Supplementary Figures from Dynamics of Genome Alterations in Crohn's Disease–Associated Colorectal Carcinogenesis

Author

Hirsch, Daniela, primary, Wangsa, Darawalee, primary, Zhu, Yuelin J., primary, Hu, Yue, primary, Edelman, Daniel C., primary, Meltzer, Paul S., primary, Heselmeyer-Haddad, Kerstin, primary, Ott, Claudia, primary, Kienle, Peter, primary, Galata, Christian, primary, Horisberger, Karoline, primary, Ried, Thomas, primary, and Gaiser, Timo, primary

Published
2023
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36. Supplementary Table from Dynamics of Genome Alterations in Crohn's Disease–Associated Colorectal Carcinogenesis

Author

Hirsch, Daniela, primary, Wangsa, Darawalee, primary, Zhu, Yuelin J., primary, Hu, Yue, primary, Edelman, Daniel C., primary, Meltzer, Paul S., primary, Heselmeyer-Haddad, Kerstin, primary, Ott, Claudia, primary, Kienle, Peter, primary, Galata, Christian, primary, Horisberger, Karoline, primary, Ried, Thomas, primary, and Gaiser, Timo, primary

Published
2023
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38. Supplementary Table 1 from Polycomb Repressor Complex-2 Is a Novel Target for Mesothelioma Therapy

Author

Kemp, Clinton D., primary, Rao, Mahadev, primary, Xi, Sichuan, primary, Inchauste, Suzanne, primary, Mani, Haresh, primary, Fetsch, Patricia, primary, Filie, Armando, primary, Zhang, Mary, primary, Hong, Julie A., primary, Walker, Robert L., primary, Zhu, Yuelin J., primary, Ripley, R. Taylor, primary, Mathur, Aarti, primary, Liu, Fang, primary, Yang, Maocheng, primary, Meltzer, Paul A., primary, Marquez, Victor E., primary, De Rienzo, Assunta, primary, Bueno, Raphael, primary, and Schrump, David S., primary

Published
2023
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39. Supplementary Figure 4 from Polycomb Repressor Complex-2 Is a Novel Target for Mesothelioma Therapy

Author

Kemp, Clinton D., primary, Rao, Mahadev, primary, Xi, Sichuan, primary, Inchauste, Suzanne, primary, Mani, Haresh, primary, Fetsch, Patricia, primary, Filie, Armando, primary, Zhang, Mary, primary, Hong, Julie A., primary, Walker, Robert L., primary, Zhu, Yuelin J., primary, Ripley, R. Taylor, primary, Mathur, Aarti, primary, Liu, Fang, primary, Yang, Maocheng, primary, Meltzer, Paul A., primary, Marquez, Victor E., primary, De Rienzo, Assunta, primary, Bueno, Raphael, primary, and Schrump, David S., primary

Published
2023
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40. Supplementary Materials and Methods from Polycomb Repressor Complex-2 Is a Novel Target for Mesothelioma Therapy

Author

Kemp, Clinton D., primary, Rao, Mahadev, primary, Xi, Sichuan, primary, Inchauste, Suzanne, primary, Mani, Haresh, primary, Fetsch, Patricia, primary, Filie, Armando, primary, Zhang, Mary, primary, Hong, Julie A., primary, Walker, Robert L., primary, Zhu, Yuelin J., primary, Ripley, R. Taylor, primary, Mathur, Aarti, primary, Liu, Fang, primary, Yang, Maocheng, primary, Meltzer, Paul A., primary, Marquez, Victor E., primary, De Rienzo, Assunta, primary, Bueno, Raphael, primary, and Schrump, David S., primary

Published
2023
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41. Supplementary Data from Mutant Idh2 Cooperates with a NUP98-HOXD13 Fusion to Induce Early Immature Thymocyte Precursor ALL

Author

Goldberg, Liat, primary, Negi, Vijay, primary, Chung, Yang Jo, primary, Onozawa, Masahiro, primary, Zhu, Yuelin J., primary, Walker, Robert L., primary, Pierce, Rachel, primary, Patel, Daxesh P., primary, Krausz, Kristopher W., primary, Gonzalez, Frank J., primary, Goodell, Margaret A., primary, Rodriguez, Benjamin A.T., primary, Meltzer, Paul S., primary, and Aplan, Peter D., primary

Published
2023
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42. Supplementary Figure 6 from Polycomb Repressor Complex-2 Is a Novel Target for Mesothelioma Therapy

Author

Kemp, Clinton D., primary, Rao, Mahadev, primary, Xi, Sichuan, primary, Inchauste, Suzanne, primary, Mani, Haresh, primary, Fetsch, Patricia, primary, Filie, Armando, primary, Zhang, Mary, primary, Hong, Julie A., primary, Walker, Robert L., primary, Zhu, Yuelin J., primary, Ripley, R. Taylor, primary, Mathur, Aarti, primary, Liu, Fang, primary, Yang, Maocheng, primary, Meltzer, Paul A., primary, Marquez, Victor E., primary, De Rienzo, Assunta, primary, Bueno, Raphael, primary, and Schrump, David S., primary

Published
2023
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44. Supplementary Figure 3 from Polycomb Repressor Complex-2 Is a Novel Target for Mesothelioma Therapy

Author

Kemp, Clinton D., primary, Rao, Mahadev, primary, Xi, Sichuan, primary, Inchauste, Suzanne, primary, Mani, Haresh, primary, Fetsch, Patricia, primary, Filie, Armando, primary, Zhang, Mary, primary, Hong, Julie A., primary, Walker, Robert L., primary, Zhu, Yuelin J., primary, Ripley, R. Taylor, primary, Mathur, Aarti, primary, Liu, Fang, primary, Yang, Maocheng, primary, Meltzer, Paul A., primary, Marquez, Victor E., primary, De Rienzo, Assunta, primary, Bueno, Raphael, primary, and Schrump, David S., primary

Published
2023
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45. Supplementary Table 5 from Polycomb Repressor Complex-2 Is a Novel Target for Mesothelioma Therapy

Author

Kemp, Clinton D., primary, Rao, Mahadev, primary, Xi, Sichuan, primary, Inchauste, Suzanne, primary, Mani, Haresh, primary, Fetsch, Patricia, primary, Filie, Armando, primary, Zhang, Mary, primary, Hong, Julie A., primary, Walker, Robert L., primary, Zhu, Yuelin J., primary, Ripley, R. Taylor, primary, Mathur, Aarti, primary, Liu, Fang, primary, Yang, Maocheng, primary, Meltzer, Paul A., primary, Marquez, Victor E., primary, De Rienzo, Assunta, primary, Bueno, Raphael, primary, and Schrump, David S., primary

Published
2023
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46. Supplementary Figure 1 from Polycomb Repressor Complex-2 Is a Novel Target for Mesothelioma Therapy

Author

Kemp, Clinton D., primary, Rao, Mahadev, primary, Xi, Sichuan, primary, Inchauste, Suzanne, primary, Mani, Haresh, primary, Fetsch, Patricia, primary, Filie, Armando, primary, Zhang, Mary, primary, Hong, Julie A., primary, Walker, Robert L., primary, Zhu, Yuelin J., primary, Ripley, R. Taylor, primary, Mathur, Aarti, primary, Liu, Fang, primary, Yang, Maocheng, primary, Meltzer, Paul A., primary, Marquez, Victor E., primary, De Rienzo, Assunta, primary, Bueno, Raphael, primary, and Schrump, David S., primary

Published
2023
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48. Supplementary Table 2 from Polycomb Repressor Complex-2 Is a Novel Target for Mesothelioma Therapy

Author

Kemp, Clinton D., primary, Rao, Mahadev, primary, Xi, Sichuan, primary, Inchauste, Suzanne, primary, Mani, Haresh, primary, Fetsch, Patricia, primary, Filie, Armando, primary, Zhang, Mary, primary, Hong, Julie A., primary, Walker, Robert L., primary, Zhu, Yuelin J., primary, Ripley, R. Taylor, primary, Mathur, Aarti, primary, Liu, Fang, primary, Yang, Maocheng, primary, Meltzer, Paul A., primary, Marquez, Victor E., primary, De Rienzo, Assunta, primary, Bueno, Raphael, primary, and Schrump, David S., primary

Published
2023
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49. Supplementary Table 3 from Polycomb Repressor Complex-2 Is a Novel Target for Mesothelioma Therapy

Author

Kemp, Clinton D., primary, Rao, Mahadev, primary, Xi, Sichuan, primary, Inchauste, Suzanne, primary, Mani, Haresh, primary, Fetsch, Patricia, primary, Filie, Armando, primary, Zhang, Mary, primary, Hong, Julie A., primary, Walker, Robert L., primary, Zhu, Yuelin J., primary, Ripley, R. Taylor, primary, Mathur, Aarti, primary, Liu, Fang, primary, Yang, Maocheng, primary, Meltzer, Paul A., primary, Marquez, Victor E., primary, De Rienzo, Assunta, primary, Bueno, Raphael, primary, and Schrump, David S., primary

Published
2023
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50. Supplementary Figure 5 from Polycomb Repressor Complex-2 Is a Novel Target for Mesothelioma Therapy

Author

Kemp, Clinton D., primary, Rao, Mahadev, primary, Xi, Sichuan, primary, Inchauste, Suzanne, primary, Mani, Haresh, primary, Fetsch, Patricia, primary, Filie, Armando, primary, Zhang, Mary, primary, Hong, Julie A., primary, Walker, Robert L., primary, Zhu, Yuelin J., primary, Ripley, R. Taylor, primary, Mathur, Aarti, primary, Liu, Fang, primary, Yang, Maocheng, primary, Meltzer, Paul A., primary, Marquez, Victor E., primary, De Rienzo, Assunta, primary, Bueno, Raphael, primary, and Schrump, David S., primary

Published
2023
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