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Amorphous alloys are widely used as the core material for motors and transformers, which are subjected to stresses during manufacturing and operation processes. For instance, the compressive stress can influence the magnetic properties of amorphous alloys which leads to local overheating in the device and reduce the reliability. A high-frequency magnetizer with a stress application unit is designed and constructed to investigate the magnetic properties of amorphous alloys up to kilohertz range under stress conditions. The amorphous alloy sheets will fracture under stress because of their poor ductility and brittleness, so this paper uses laminated amorphous alloy sheets as the sample. The hysteresis loops and loss characteristics of amorphous alloys under stress ranging from 20 MPa tensile stress to 20 MPa compressive stress at a frequency of 50 Hz to 4 kHz are investigated. This research can provide data support for the design of cores in electromagnetic devices. [ABSTRACT FROM AUTHOR]

In recent years, developing artificial cells of higher complexity has emerged as being key to simulating advanced life behaviors, among which coacervate microdroplets are a promising kind of model artificial cell. Constructing simple coacervate systems in vitro which can subsequently achieve specific responses to environmental stimuli to form coacervate microdroplet communities are fundamental for studying the interactions between liquid–liquid phase separated molecules and the way such interactions determine material properties, composition and phase behavior. Herein, we propose a membrane-free artificial cell based on recombinant spidroin, NT2RepCT, which utilizes the complex structure of spidroin to provide coacervate microdroplets with a unique population morphology in response to environmental stimuli. By changing the environmental conditions such as protein concentration, pH and temperature, the coacervate microdroplets of single-type, regular adhesion-type and irregular adhesion-type were statistically generalized, and it is highlighted that the adhesion-type of coacervate microdroplets depended on the α-helical percentage, complex folding degree of spidroin and internally hydrophobic environment of the coacervate, while it was inversely proportional to the surface hydrophobic environment. Much more interesting, regulation of the non-enzymatic polymerization reaction of oligonucleotides was successfully achieved by adjusting the population morphology of coacervate microdroplets. [ABSTRACT FROM AUTHOR]

Analysis of the spatial and temporal variation patterns of surface evapotranspiration is important for understanding global climate change, promoting scientific deployment of regional water resources, and improving crop yield and water productivity. Based on Landsat 8 OIL_TIRS data and remote sensing image data of the lower Yangtze River urban cluster for the same period of 2016–2021, combined with soil and meteorological data of the study area, this paper constructed a multiple linear regression (MLR) model and an extreme learning machine (ELM) inversion model with evapotranspiration as the target and, based on the model inversion, quantitatively and qualitatively analyzed the spatial and temporal variability in surface evapotranspiration in the study area in the past six years. The results show that both models based on feature factors and spectral indices obtained a good inversion accuracy, with the fusion of feature factors effectively improving the inversion ability of the model for ET. The best model for ET in 2016, 2017, and 2021 was MLR, with an R2 greater than 0.8; the best model for ET in 2018–2019 was ELM, with an R2 of 0.83 and 0.62, respectively. The inter-annual ET in the study area showed a "double-peak" dynamic variation, with peaks in 2018 and 2020; the intra-annual ET showed a single-peak cycle, with peaks in July–August. Seasonal differences were obvious, and spatially high-ET areas were mainly found in rural areas north of the Yangtze River and central and western China where agricultural land is concentrated. The net solar radiation, soil heat flux, soil temperature and humidity, and fractional vegetation cover all had significant positive effects on ET, with correlation coefficients ranging from 0.39 to 0.94. This study can provide methodological and scientific support for the quantitative and qualitative estimation of regional ET. [ABSTRACT FROM AUTHOR]

Aim: This study is performed to analyze the role of long non‐coding RNA plasmacytoma variant translocation 1 in prostate cancer. Methods and materials: Plasmacytoma variant translocation 1, miR‐515‐5p, and high mobility group B3 mRNA expressions were examined using quantitative real‐time polymerase chain reaction and immunohistochemistry. After gain‐of‐function and loss‐of‐function models were established, the changes in cell proliferation, migration, and invasion were evaluated using cell counting kit‐8 assay, 5‐ethynyl‐2′‐deoxyuridine assay, and Transwell experiments. Validation of the targeting relationships between plasmacytoma variant translocation 1 and miR‐515‐5p, and between miR‐515‐5p and high mobility group B3 was conducted using bioinformatics prediction, a dual‐luciferase reporter assay, and an RNA immunoprecipitation experiment. Moreover, the effects of plasmacytoma variant translocation 1 and miR‐515‐5p on high mobility group B3 protein expression were examined using Western blot. Results: Plasmacytoma variant translocation 1 expression and high mobility group B3 expression were up‐regulated in prostate cancer tissues and cell lines while miR‐515‐5p expression was down‐regulated. Plasmacytoma variant translocation 1 knockdown restrained the proliferation, migration, and invasion of LNCaP and DU145 cells in vitro, and the transfection with miR‐515‐5p inhibitors reversed these effects. Mechanistically, plasmacytoma variant translocation 1 could repress the function of miR‐515; high mobility group B3 was proved to be a target gene of miR‐515‐5p, and its expression could be indirectly positively modulated by plasmacytoma variant translocation 1. Conclusion: Plasmacytoma variant translocation 1 accelerates prostate cancer progression by repressing miR‐515‐5p's function to upregulate high mobility group B3 expression. [ABSTRACT FROM AUTHOR]