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2,351 results on '"Zhou Xiaofeng"'

1. The function of Foxp1 represses β-adrenergic receptor transcription in the occurrence and development of bladder cancer through STAT3 activity

Author

Ding Zhenshan, Jiao Binbin, Chen Xuelong, Chen Xing, Jiao Yangtian, Wang Jianfeng, and Zhou Xiaofeng

Subjects
foxp1, β-ar, stat3, bladder cancer, warburg effect, Medicine
Abstract

Bladder cancer is a common malignant tumor. FOXP1 has been found to be abnormally expressed in tumors such as renal cell carcinoma and endometrial cancer. Here, this investigated the biological roles of Foxp1 in the occurrence and development of bladder cancer. Patients with bladder cancer were obtained from China-Japan Friendship Hospital. Bladder cancer cell lines (5637, UMUC3, J82, and T24 cell) were used in this experiment. Foxp1 mRNA and protein expression levels in patients with bladder cancer were increased, compared with paracancerous tissue (normal). OS and DFS of Foxp1 low expression in patients with bladder cancer were higher than those of Foxp1 high expression. Foxp1 promoted bladder cancer cell growth in vitro model. Foxp1 increased the Warburg effect of bladder cancer. Foxp1 suppressed β-adrenoceptor (β-AR) expression in vitro model. ChIP-seq showed that Foxp1 binding site (E1, TTATTTAT) was detected at −2,251 bp upstream of the β-AR promoter. β-AR Reduced the effects of Foxp1 on cell growth in vitro model. β-AR reduced the effects of Foxp1 on the Warburg effect in vitro model by STAT3 activity. Taken together, our findings reveal that Foxp1 promoted the occurrence and development of bladder cancer through the Warburg effect by the activation of STAT3 activity and repressing β-AR transcription, and which might serve as an important clue for its targeting and treatment of bladder cancer.

Published
2023
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2. Sports Talent Training System of Sports Aerobics Based on Fractional Differential Equation

Author

Zhou Xiaofeng and Zhang Dandan

Subjects
high school aerobics, fractional differential equation, personnel training, status quo countermeasure, 34a08, Mathematics, QA1-939
Abstract

Fractional calculus is now widely used in engineering. The complex physical properties are described accurately by using variable-order fractional-order operators. The variable fractional difference model is a powerful mathematical tool. This model is convenient for engineering simulation. This paper mainly investigates the situation of calisthenics in 2 middle schools. Secondly, the fractional differential equation studies the development status of gymnastics in China. This paper comprehensively examines the current situation of calisthenics in students’ cognition of calisthenics. The results show significant obstacles in the development of calisthenics in colleges and universities.

Published
2023
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3. Identifying intergranular pore types by distinguishing between cementation and dissolution of dotted calcite: A case study of the Xinhe Formation sandstones in the Yabrai Basin, China

Author

WANG Jianguo, ZHOU Xiaofeng, TANG Haizhong, WEI Jun, HAN Xiaosong, and GUO Wei

Subjects
dotted calcite, cementation and dissolution, intergranular pore, xinhe formation sandstones, yabrai basin, Geology, QE1-996.5
Abstract

There is still no consensus among researchers about whether intergranular pores in oil-bearing sandstone are primary pores or secondary pores. Distinguishing between cementation and dissolution of dotted calcite can effectively identify intergranular pore types. In this paper, taking the diagenetic environment evolution and diagenesis sequence as the thread, we carefully observed the casting slices from the Xinhe Formation sandstones in the Yabrai Basin and finely dissected the microphenomenon by focusing on the calcite cements in its relation between the origins of substance and dissolution fluids and the occurrence mode. The genesis of the dotted calcite was clarified thus, and then the intergranular pore types and reservoir space types in the sandstones were identified. The study results show that the dotted calcite in the intergranular pore is the dissolution residue of the disseminated calcite formed in the early diagenetic stage, and the dissolution type is the consistent dissolution. The dissolution fluid, organic acid fluid formed during the middle diagenetic stage, caused the secondary pores. Therefore, it is concluded that the reservoir space in the Xinhe Formation sandstones in the Yabrai Basin consists of the secondary intergranular pores and the secondary intragranular pores such as dissolution pores of cements of feldspar, lithoclast, lithoclast.

Published
2021
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4. Haplotype-resolved genome assembly and resequencing provide insights into the origin and breeding of modern rose

Author

Zhang, Zhao, Yang, Tuo, Liu, Yang, Wu, Shan, Sun, Honghe, Wu, Jie, Li, Yonghong, Zheng, Yi, Ren, Haoran, Yang, Yuyong, Shi, Shaochuan, Wang, Wenyan, Pan, Qi, Lian, Lijuan, Duan, Shaowen, Zhu, Yingxiong, Cai, Youming, Zhou, Hougao, Zhang, Hao, Tang, Kaixue, Cui, Jiaopeng, Gao, Dan, Chen, Liyang, Jiang, Yunhe, Sun, Xiaoming, Zhou, Xiaofeng, Fei, Zhangjun, Ma, Nan, and Gao, Junping

Published
2024
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15. Ethylene controls cambium stem cell activity via promoting local auxin biosynthesis

Author

Yu, Qin, Cheng, Chenxia, Zhou, Xiaofeng, Li, Yonghong, Hu, Yingchun, Yang, Chun, Zhou, Yingying, Soliman, Tarek MA, Zhang, Hao, Wang, Qigang, Wang, Huichun, Jiang, Cai‐Zhong, Gan, Su‐Sheng, Gao, Junping, and Ma, Nan

Subjects
Plant Biology, Biological Sciences, Cambium, Plant Growth Regulators, Indoleacetic Acids, Ethylenes, Xylem, Stem Cells, Gene Expression Regulation, Plant, auxin, cambium, ethylene, HD-ZIP I transcription factor, Rosa hybrida, Rosa hybrida, Agricultural and Veterinary Sciences, Plant Biology & Botany, Plant biology, Climate change impacts and adaptation, Ecological applications
Abstract

The vascular cambium is the main secondary meristem in plants that produces secondary phloem (outside) and xylem (inside) on opposing sides of the cambium. The phytohormone ethylene has been implicated in vascular cambium activity, but the regulatory network underlying ethylene-mediated cambial activity remains to be elucidated. Here, we found that PETAL MOVEMENT-RELATED PROTEIN1 (RhPMP1), an ethylene-inducible HOMEODOMAIN-LEUCINE ZIPPER I transcription factor in woody plant rose (Rosa hybrida), regulates local auxin biosynthesis and auxin transport to maintain cambial activity. Knockdown of RhPMP1 resulted in smaller midveins and reduced auxin content, while RhPMP1 overexpression resulted in larger midveins and increased auxin levels compared with the wild-type plants. Furthermore, we revealed that Indole-3-pyruvate monooxygenase YUCCA 10 (RhYUC10) and Auxin transporter-like protein 2 (RhAUX2), encoding an auxin biosynthetic enzyme and an auxin influx carrier, respectively, are direct downstream targets of RhPMP1. In summary, our results suggest that ethylene promotes an auxin maximum in the cambium adjacent to the xylem to maintain cambial activity.

Published
2023

16. Abnormal Vibration Fault Diagnosis of Reducer Based on Bayesian Network

Author

Tan, Xin, Zhong, Jingshu, Zhou, Xiaofeng, Wang, Zixin, Zhou, Anye, Zheng, Yu, Hartmanis, Juris, Founding Editor, van Leeuwen, Jan, Series Editor, Hutchison, David, Editorial Board Member, Kanade, Takeo, Editorial Board Member, Kittler, Josef, Editorial Board Member, Kleinberg, Jon M., Editorial Board Member, Kobsa, Alfred, Series Editor, Mattern, Friedemann, Editorial Board Member, Mitchell, John C., Editorial Board Member, Naor, Moni, Editorial Board Member, Nierstrasz, Oscar, Series Editor, Pandu Rangan, C., Editorial Board Member, Sudan, Madhu, Series Editor, Terzopoulos, Demetri, Editorial Board Member, Tygar, Doug, Editorial Board Member, Weikum, Gerhard, Series Editor, Vardi, Moshe Y, Series Editor, Goos, Gerhard, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Woeginger, Gerhard, Editorial Board Member, Le, Xinyi, editor, and Zhang, Zhijun, editor

Published
2024
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32. Cluster magnetic octupole induced out-of-plane spin polarization in antiperovskite antiferromagnet

Author

You, Yunfeng, Bai, Hua, Feng, Xiaoyu, Fan, Xiaolong, Han, Lei, Zhou, Xiaofeng, Zhou, Yongjian, Zhang, Ruiqi, Chen, Tongjin, Pan, Feng, and Song, Cheng

Subjects
Condensed Matter - Materials Science
Abstract

Out-of-plane spin polarization {\sigma}_z has attracted increasing interests of researchers recently, due to its potential in high-density and low-power spintronic devices. Noncollinear antiferromagnet (AFM), which has unique 120{\deg} triangular spin configuration, has been discovered to possess {\sigma}_z. However, the physical origin of {\sigma}_z in noncollinear AFM is still not clear, and the external magnetic field-free switching of perpendicular magnetic layer using the corresponding {\sigma}_z has not been reported yet. Here, we use the cluster magnetic octupole in antiperovskite AFM Mn3SnN to demonstrate the generation of {\sigma}_z. {\sigma}_z is induced by the precession of carrier spins when currents flow through the cluster magnetic octupole, which also relies on the direction of the cluster magnetic octupole in conjunction with the applied current. With the aid of {\sigma}_z, current induced spin-orbit torque (SOT) switching of adjacent perpendicular ferromagnet is realized without external magnetic field. Our findings present a new perspective to the generation of out-of-plane spin polarizations via noncollinear AFM spin structure, and provide a potential path to realize ultrafast high-density applications., Comment: 23 pages, 4 figures, accepted by Nat. Commun

Published
2021
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38. The persistence of SARS-CoV-2 in tissues and its association with long COVID symptoms: a cross-sectional cohort study in China

Author

Zuo, Wenting, He, Di, Liang, Chaoyang, Du, Shiyu, Hua, Zhan, Nie, Qiangqiang, Zhou, Xiaofeng, Yang, Meng, Tan, Haidong, Xu, Jiuyang, Yu, Yanbing, Zhan, Yuliang, Zhang, Ying, Gu, Xiaoying, Zhu, Weijie, Zhang, Hui, Li, Hongyan, Sun, Weiliang, Sun, Mingzhi, Liu, Xiaolei, Liu, Liguo, Cao, Chuanzhen, Li, Rui, Li, Jing, Zhang, Yun, Zhang, Yuting, Guo, Jing, Zhao, Ling, Zhang, Chuan-Peng, Liu, Hongyu, Wang, Shiyao, Xiao, Fei, Wang, Yeming, Wang, Zai, Li, Haibo, and Cao, Bin

Published
2024
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50. Magnon-mediated interlayer coupling in an all-antiferromagnetic junction

Author

Zhou, Yongjian, Liao, Liyang, Zhou, Xiaofeng, Bai, Hua, Zhao, Mingkun, Wan, Caihua, Yin, Siqi, Huang, Lin, Guo, Tingwen, Han, Lei, Chen, Ruyi, Zhou, Zhiyuan, Han, Xiufeng, Pan, Feng, and Song, Cheng

Subjects
Condensed Matter - Materials Science
Abstract

The interlayer coupling mediated by fermions in ferromagnets brings about parallel and anti-parallel magnetization orientations of two magnetic layers, resulting in the giant magnetoresistance, which forms the foundation in spintronics and accelerates the development of information technology. However, the interlayer coupling mediated by another kind of quasi-particle, boson, is still lacking. Here we demonstrate such a static interlayer coupling at room temperature in an antiferromagnetic junction Fe2O3/Cr2O3/Fe2O3, where the two antiferromagnetic Fe2O3 layers are functional materials and the antiferromagnetic Cr2O3 layer serves as a spacer. The N\'eel vectors in the top and bottom Fe2O3 are strongly orthogonally coupled, which is bridged by a typical bosonic excitation (magnon) in the Cr2O3 spacer. Such an orthogonally coupling exceeds the category of traditional collinear interlayer coupling via fermions in ground state, reflecting the fluctuating nature of the magnons, as supported by our magnon quantum well model. Besides the fundamental significance on the quasi-particle-mediated interaction, the strong coupling in an antiferromagnetic magnon junction makes it a realistic candidate for practical antiferromagnetic spintronics and magnonics with ultrahigh-density integration., Comment: 19 pages, 4 figures

Published
2021
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