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Costal cartilage segmentation is crucial to various medical applications, necessitating precise and reliable techniques due to its complex anatomy and the importance of accurate diagnosis and surgical planning. We propose a novel deep learning-based approach called topology-guided deformable Mamba (TGDM) for costal cartilage segmentation. The TGDM is tailored to capture the intricate long-range costal cartilage relationships. Our method leverages a deformable model that integrates topological priors to enhance the adaptability and accuracy of the segmentation process. Furthermore, we developed a comprehensive benchmark that contains 165 cases for costal cartilage segmentation. This benchmark sets a new standard for evaluating costal cartilage segmentation techniques and provides a valuable resource for future research. Extensive experiments conducted on both in-domain benchmarks and out-of domain test sets demonstrate the superiority of our approach over existing methods, showing significant improvements in segmentation precision and robustness.

Developing superior quantum sensing strategies ranging from ultra-high precision measurement to complex structural analysis is at the heart of quantum technologies. While strategies using quantum resources, such as entanglement among sensors, to enhance the sensing precision have been abundantly demonstrated, the signal correlation among quantum sensors is rarely exploited. Here we develop a novel sensing paradigm exploiting the signal correlation among multiple quantum sensors to resolve overlapping signals from multiple targets that individual sensors can't resolve and complex structural construction struggles with. With three nitrogen-vacancy centers as a quantum electrometer system, we demonstrate this multi-sensor paradigm by resolving individual defects' fluctuating electric fields from ensemble signals. We image the three-dimensional distribution of 16 dark electronic point-defects in diamond with accuracy approaching 1.7 nm via a GPS-like localization method. Furthermore, we obtain the real-time charge dynamics of individual point defects and visualize how the dynamics induce the well-known optical spectral diffusion. The multi-sensor paradigm extends the quantum sensing toolbox and offers new possibilities for structural analysis.

Quantifying similarity between neural representations -- e.g. hidden layer activation vectors -- is a perennial problem in deep learning and neuroscience research. Existing methods compare deterministic responses (e.g. artificial networks that lack stochastic layers) or averaged responses (e.g., trial-averaged firing rates in biological data). However, these measures of _deterministic_ representational similarity ignore the scale and geometric structure of noise, both of which play important roles in neural computation. To rectify this, we generalize previously proposed shape metrics (Williams et al. 2021) to quantify differences in _stochastic_ representations. These new distances satisfy the triangle inequality, and thus can be used as a rigorous basis for many supervised and unsupervised analyses. Leveraging this novel framework, we find that the stochastic geometries of neurobiological representations of oriented visual gratings and naturalistic scenes respectively resemble untrained and trained deep network representations. Further, we are able to more accurately predict certain network attributes (e.g. training hyperparameters) from its position in stochastic (versus deterministic) shape space., Comment: Published as a conference paper at ICLR 2023

Learning to optimize (L2O) has gained increasing attention since classical optimizers require laborious problem-specific design and hyperparameter tuning. However, there is a gap between the practical demand and the achievable performance of existing L2O models. Specifically, those learned optimizers are applicable to only a limited class of problems, and often exhibit instability. With many efforts devoted to designing more sophisticated L2O models, we argue for another orthogonal, under-explored theme: the training techniques for those L2O models. We show that even the simplest L2O model could have been trained much better. We first present a progressive training scheme to gradually increase the optimizer unroll length, to mitigate a well-known L2O dilemma of truncation bias (shorter unrolling) versus gradient explosion (longer unrolling). We further leverage off-policy imitation learning to guide the L2O learning, by taking reference to the behavior of analytical optimizers. Our improved training techniques are plugged into a variety of state-of-the-art L2O models, and immediately boost their performance, without making any change to their model structures. Especially, by our proposed techniques, an earliest and simplest L2O model can be trained to outperform the latest complicated L2O models on a number of tasks. Our results demonstrate a greater potential of L2O yet to be unleashed, and urge to rethink the recent progress. Our codes are publicly available at: https://github.com/VITA-Group/L2O-Training-Techniques., Comment: NeurIPS 2020 Spotlight Oral

With the trend of adversarial attacks, researchers attempt to fool trained object detectors in 2D scenes. Among many of them, an intriguing new form of attack with potential real-world usage is to append adversarial patches (e.g. logos) to images. Nevertheless, much less have we known about adversarial attacks from 3D rendering views, which is essential for the attack to be persistently strong in the physical world. This paper presents a new 3D adversarial logo attack: we construct an arbitrary shape logo from a 2D texture image and map this image into a 3D adversarial logo via a texture mapping called logo transformation. The resulting 3D adversarial logo is then viewed as an adversarial texture enabling easy manipulation of its shape and position. This greatly extends the versatility of adversarial training for computer graphics synthesized imagery. Contrary to the traditional adversarial patch, this new form of attack is mapped into the 3D object world and back-propagates to the 2D image domain through differentiable rendering. In addition, and unlike existing adversarial patches, our new 3D adversarial logo is shown to fool state-of-the-art deep object detectors robustly under model rotations, leading to one step further for realistic attacks in the physical world. Our codes are available at https://github.com/TAMU-VITA/3D_Adversarial_Logo.