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11 results on '"Zhou, Dakai"'

2. Compact Chromatic Confocal Lens with Large Measurement Range.

Author

He, Ning, Hu, Huiqin, Cui, Zhiying, Xu, Xinjun, Zhou, Dakai, Chen, Yunbo, Gong, Puyin, Chen, Youhua, and Kuang, Cuifang

Subjects
OPTICAL dispersion, NUMERICAL apertures, ENERGY consumption, DETECTORS, SPECTROMETERS
Abstract

Spectral confocal sensors are effective for measuring displacements. The core of the spectral confocal measurement system is a dispersive objective lens that uses optical dispersion to establish a one-to-one correspondence between the focusing position and wavelength, achieving high-resolution measurements in the longitudinal direction. Despite significant progress in dispersive objective lenses for spectral confocal sensor systems, challenges such as a limited dispersion range, high cost, and insufficient measurement accuracy persist. To expand the measurement range and improve the accuracy of the spectral confocal sensor, we designed a compact, long-axial dispersion objective lens. This lens has a simple structure that requires only six lens elements, two of which form cemented doublets. The system length is 58 mm, with a working distance of 46 ± 6 mm and a dispersion range of 12 mm within the wavelength range of 450–656 nm. The lens has an object-side numerical aperture (NA) of 0.22 and an image-side NA between 0.198 and 0.24, ensuring high light energy utilization. Finally, a spectral confocal measurement system was constructed based on the designed dispersive objective lens, and performance evaluation tests were conducted. The test results showed that the system achieved a resolution of 0.15 μm and a maximum linear error of ±0.7 μm, demonstrating high-precision measurement capabilities. The proposed lens design enables the development of more portable and cost-effective spectral confocal sensors. [ABSTRACT FROM AUTHOR]

Published
2024
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6. Global Asymptotic Synchronization of Coupled Interconnected Recurrent Neural Networks via Pinning Control

Author

Wang, Zhanshan, Zhou, Dakai, Ma, Dongsheng, Lun, Shuxian, Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Pandu Rangan, C., editor, Steffen, Bernhard, editor, Sudan, Madhu, editor, Terzopoulos, Demetri, editor, Tygar, Doug, editor, Vardi, Moshe Y., editor, Weikum, Gerhard, editor, Wang, Jun, editor, Yen, Gary G., editor, and Polycarpou, Marios M., editor

Published
2012
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7. MXene Surface on Multiple Junction Triangles for Determining Osteosarcoma Cancer Biomarker by Dielectrode Microgap Sensor

Author

Zhou, Dakai, Gopinath, Subash C B, Mohamed Saheed, Mohamed Shuaib, Siva Sangu, Sangeetha, and Lakshmipriya, Thangavel

Subjects
microdevice, Osteosarcoma, Photoelectron Spectroscopy, Survivin, Reproducibility of Results, bone cancer, Bone Neoplasms, Biosensing Techniques, DNA, Neoplasm, biosensor, Nanostructures, International Journal of Nanomedicine, Cell Line, Tumor, Biomarkers, Tumor, Transition Elements, biomarker, Humans, survivin gene, MXene, Electrodes, Microelectrodes, Original Research
Abstract

Dakai Zhou,1 Subash CB Gopinath,2,3 Mohamed Shuaib Mohamed Saheed,4,5 Sangeetha Siva Sangu,5,6 Thangavel Lakshmipriya3 1Department of Spinal Surgery, Xinxiang Central Hospital, Xinxiang City, Henan Province 453000, People’s Republic of China; 2Faculty of Chemical Engineering Technology, Universiti Malaysia Perlis (UniMAP), Arau, Perlis 02600, Malaysia; 3Institute of Nano Electronic Engineering, Universiti Malaysia Perlis (UniMAP), Kangar, Perlis 01000, Malaysia; 4Department of Mechanical Engineering, Universiti Teknologi PETRONAS, Seri Iskandar 32610, Perak Darul Ridzuan, Malaysia; 5Centre of Innovative Nanostructures & Nanodevices (COINN), Universiti Teknologi PETRONAS, Seri Iskandar 32610, Perak Darul Ridzuan, Malaysia; 6Department of Fundamental & Applied Sciences, Universiti Teknologi PETRONAS, Seri Iskandar 32610, Perak Darul Ridzuan, MalaysiaCorrespondence: Subash CB Gopinath Email subash@unimap.edu.myBackground: In recent years, nanomaterials have justified their dissemination for biosensor application towards the sensitive and selective detections of clinical biomarkers at the lower levels. MXene is a two-dimensional layered transition metal, attractive for biosensing due to its chemical, physical and electrical properties along with the biocompatibility.Materials and Methods: This work was focused on diagnosing osteosarcoma (OS), a common bone cancer, on MXene-modified multiple junction triangles by dielectrode sensing. Survivin protein gene is highly correlated with OS, identified on this sensing surface. Capture DNA was immobilized on MXene by using 3-glycidoxypropyltrimethoxysilane as an amine linker and duplexed by the target DNA sequence.Results: The limitation and sensitivity of detection were found as 1 fM with the acceptable regression co-efficient value (y=1.0037⨰ + 0.525; R2=0.978) and the current enhancement was noted when increasing the target DNA concentrations. Moreover, the control sequences of single- and triple-mismatched and noncomplementary to the target DNA sequences failed to hybridize on the capture DNA, confirming the specificity. In addition, different batches were prepared with capture probe immobilized sensing surfaces and proved the efficient reproducibility.Conclusion: This microgap device with Mxene-modified multiple junction triangles dielectrode surface is beneficial to quantify the survivin gene at its lower level and diagnosing OS complication levels.Keywords: MXene, biosensor, bone cancer, microdevice, biomarker, survivin gene

Published
2020

9. MXene Surface on Multiple Junction Triangles for Determining Osteosarcoma Cancer Biomarker by Dielectrode Microgap Sensor

Author

Zhou,Dakai, Gopinath,Subash CB, Mohamed Saheed,Mohamed Shuaib, Siva Sangu,Sangeetha, Lakshmipriya,Thangavel, Zhou,Dakai, Gopinath,Subash CB, Mohamed Saheed,Mohamed Shuaib, Siva Sangu,Sangeetha, and Lakshmipriya,Thangavel

Abstract

Dakai Zhou,1 Subash CB Gopinath,2,3 Mohamed Shuaib Mohamed Saheed,4,5 Sangeetha Siva Sangu,5,6 Thangavel Lakshmipriya3 1Department of Spinal Surgery, Xinxiang Central Hospital, Xinxiang City, Henan Province 453000, People’s Republic of China; 2Faculty of Chemical Engineering Technology, Universiti Malaysia Perlis (UniMAP), Arau, Perlis 02600, Malaysia; 3Institute of Nano Electronic Engineering, Universiti Malaysia Perlis (UniMAP), Kangar, Perlis 01000, Malaysia; 4Department of Mechanical Engineering, Universiti Teknologi PETRONAS, Seri Iskandar 32610, Perak Darul Ridzuan, Malaysia; 5Centre of Innovative Nanostructures & Nanodevices (COINN), Universiti Teknologi PETRONAS, Seri Iskandar 32610, Perak Darul Ridzuan, Malaysia; 6Department of Fundamental & Applied Sciences, Universiti Teknologi PETRONAS, Seri Iskandar 32610, Perak Darul Ridzuan, MalaysiaCorrespondence: Subash CB Gopinath Email subash@unimap.edu.myBackground: In recent years, nanomaterials have justified their dissemination for biosensor application towards the sensitive and selective detections of clinical biomarkers at the lower levels. MXene is a two-dimensional layered transition metal, attractive for biosensing due to its chemical, physical and electrical properties along with the biocompatibility.Materials and Methods: This work was focused on diagnosing osteosarcoma (OS), a common bone cancer, on MXene-modified multiple junction triangles by dielectrode sensing. Survivin protein gene is highly correlated with OS, identified on this sensing surface. Capture DNA was immobilized on MXene by using 3-glycidoxypropyltrimethoxysilane as an amine linker and duplexed by the target DNA sequence.Results: The limitation and sensitivity of detection were found as 1 fM with the acceptable regression co-efficient value (y=1.0037⨰ + 0.525; R2=0.978) and the current enhancement was noted when increasing the target DNA concentrations. Moreover, the control sequences of single- and triple-m

Published
2020

11. Full field-of-view hexagonal lattice structured illumination microscopy based on the phase shift of electro-optic modulators.

Author

Ji C, Zhu Y, He E, Liu Q, Zhou D, Xie S, Wu H, Zhang J, Du K, Chen Y, Liu W, and Kuang C

Abstract

High throughput has become an important research direction in the field of super-resolution (SR) microscopy, especially in improving the capability of dynamic observations. In this study, we present a hexagonal lattice structured illumination microscopy (hexSIM) system characterized by a large field of view (FOV), rapid imaging speed, and high power efficiency. Our approach employs spatial light interference to generate a two-dimensional hexagonal SIM pattern, and utilizes electro-optical modulators for high-speed phase shifting. This design enables the achievement of a 210-µm diameter SIM illumination FOV when using a 100×/1.49 objective lens, capturing 2048 × 2048 pixel images at an impressive 98 frames per second (fps) single frame rate. Notably, this method attains a near 100% full field-of-view and power efficiency, with the speed limited only by the camera's capabilities. Our hexSIM demonstrates a substantial 1.73-fold improvement in spatial resolution and necessitates only seven phase-shift images, thus enhancing the imaging speed compared to conventional 2D-SIM.

Published
2024
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