Search

Your search keyword '"Zheng, Xiangde"' showing total 28 results
Start Over Author "Zheng, Xiangde"
28 results on '"Zheng, Xiangde"'

3. Effect of early enteral nutrition combined with probiotics on the therapeutic effect and prognosis of patients with severe multiple injuries

Author

XU Hao*, TIAN Lin, ZHENG Xiangde

Subjects
multiple injuries， probiotics， early enteral nutrition， intestinal barrier， nutritional status, Medicine
Abstract

Objective To investigate the effect and prognosis of early enteral nutrition (EEN) combined with probiotics on patients with severe multiple injuries. Methods A total of 110 patients with multiple injuries who scored＞16 points on the trauma severity score in the Intensive Care Unit of Dazhou Central Hospital from July 2022 to July 2023 were collected and divided into control group (55 cases) and observation group (55 cases) using a random number table method. The control group received EEN support, while the observation group received EEN combined with probiotic nutritional support. Serum diamine oxidase (DAO), D-lactic acid (D-La), total protein (PB), prealbumin (PAB), C-reactive protein (CRP), and white blood cell count (WBC) were compared between the two groups before and after treatment. The length of ICU stay, incidence of gastrointestinal adverse events, and 28-day mortality rate were statistically analyzed for both groups. Results After treatment, serum DAO, D-La, CRP, and WBC levels in both groups were lower than before treatment, with the observation group having lower levels than the control group ［(7.77±1.03) ng/L vs (8.84±0.63) ng/L, (48.25±7.23) mg/L vs (53.85±6.44) mg/L, (33.43±17.28) mg/L vs (43.44±19.13) mg/L, (7.48±1.56)×109/L vs (9.77±1.30)×109/L］, with a significant difference (P＜0.05); post-treatment TP and PAB levels in both groups were higher than before treatment, with the observation group having higher levels than the control group ［(58.80±2.83) g/L vs (54.43±2.06) g/L, (175.93±5.78) g/L vs (159.16±8.06) g/L］, with a significant difference (P＜0.05); the incidence of gastrointestinal adverse events in the observation group was lower than that in the control group (26.1% vs 46.5%), with a significant difference (P＜0.05); however, there was no significant difference in ICU stay or 28-day mortality rate between the two groups (P＞0.05). Conclusion EEN combined with probiotics can effectively protect the intestinal mucosal barrier of patients with severe multiple injuries, improve their nutritional status, and reduce the incidence of gastrointestinal adverse events, but it has no significant impact on the ICU stay or 28-day mortality rate of patients with severe multiple injuries.

Published
2024
Full Text
View/download PDF

6. Correction to: Actively implementing an evidence-based feeding guideline for critically ill patients (NEED): a multicenter, cluster-randomized, controlled trial

Author

Ke, Lu, Lin, Jiajia, Doig, Gordon S., van Zanten, Arthur R. H., Wang, Yang, Xing, Juan, Zhang, Zhongheng, Chen, Tao, Zhou, Lixin, Jiang, Dongpo, Shi, Qindong, Lin, Jiandong, Liu, Jun, Cheng, Aibin, Liang, Yafeng, Gao, Peiyang, Sun, Junli, Liu, Wenming, Yang, Zhenyu, Zhang, Rumin, Xing, Wei, Zhang, An, Zhou, Zhigang, Zhou, Tingfa, Liu, Yang, Tong, Fei, Wang, Qiuhui, Pan, Aijun, Huang, Xiaobo, Fan, Chuming, Lu, Weihua, Shi, Dongwu, Wang, Lei, Li, Wei, Gu, Liming, Xie, Yingguang, Sun, Rongqing, Guo, Feng, Han, Lin, Zhou, Lihua, Zheng, Xiangde, Shan, Feng, Liu, Jianbo, Ai, Yuhang, Qu, Yan, Li, Liandi, Li, Hailing, Pan, Zhiguo, Xu, Donglin, Zou, Zhiqiang, Gao, Yan, Yang, Chunli, Kou, Qiuye, Zhang, Xijing, Wu, Jinglan, Qian, Chuanyun, Zhang, Weixing, Zhang, Minjie, Zong, Yuan, Qin, Bingyu, Zhang, Fusen, Zhai, Zhe, Sun, Yun, Chang, Ping, Yu, Bo, Yu, Min, Yuan, Shiying, Deng, Yijun, Zhao, Liyun, Zang, Bin, Li, Yuanfei, Zhou, Fachun, Chen, Xiaomei, Shao, Min, Wu, Weidong, Wu, Ming, Zhang, Zhaohui, Li, Yimin, Guo, Qiang, Wang, Zhiyong, Gong, Yuanqi, Song, Yunlin, Qian, Kejian, Feng, Yongjian, Fu, Baocai, Liu, Xueyan, Li, Zhiping, Gong, Chuanyong, Sun, Cheng, Yu, Jian, Tang, Zhongzhi, Huang, Linxi, Ma, Biao, He, Zhijie, Zhou, Qingshan, Yu, Rongguo, Tong, Zhihui, and Li, Weiqin

Published
2022
Full Text
View/download PDF

7. Actively implementing an evidence-based feeding guideline for critically ill patients (NEED): a multicenter, cluster-randomized, controlled trial

Author

Ke, Lu, Lin, Jiajia, Doig, Gordon S., van Zanten, Arthur R. H., Wang, Yang, Xing, Juan, Zhang, Zhongheng, Chen, Tao, Zhou, Lixin, Jiang, Dongpo, Shi, Qindong, Lin, Jiandong, Liu, Jun, Cheng, Aibin, Liang, Yafeng, Gao, Peiyang, Sun, Junli, Liu, Wenming, Yang, Zhenyu, Zhang, Rumin, Xing, Wei, Zhang, An, Zhou, Zhigang, Zhou, Tingfa, Liu, Yang, Tong, Fei, Wang, Qiuhui, Pan, Aijun, Huang, Xiaobo, Fan, Chuming, Lu, Weihua, Shi, Dongwu, Wang, Lei, Li, Wei, Gu, Liming, Xie, Yingguang, Sun, Rongqing, Guo, Feng, Han, Lin, Zhou, Lihua, Zheng, Xiangde, Shan, Feng, Liu, Jianbo, Ai, Yuhang, Qu, Yan, Li, Liandi, Li, Hailing, Pan, Zhiguo, Xu, Donglin, Zou, Zhiqiang, Gao, Yan, Yang, Chunli, Kou, Qiuye, Zhang, Xijing, Wu, Jinglan, Qian, Chuanyun, Zhang, Weixing, Zhang, Minjie, Zong, Yuan, Qin, Bingyu, Zhang, Fusen, Zhai, Zhe, Sun, Yun, Chang, Ping, Yu, Bo, Yu, Min, Yuan, Shiying, Deng, Yijun, Zhao, Liyun, Zang, Bin, Li, Yuanfei, Zhou, Fachun, Chen, Xiaomei, Shao, Min, Wu, Weidong, Wu, Ming, Zhang, Zhaohui, Li, Yimin, Guo, Qiang, Wang, Zhiyong, Gong, Yuanqi, Song, Yunlin, Qian, Kejian, Feng, Yongjian, Fu, Baocai, Liu, Xueyan, Li, Zhiping, Gong, Chuanyong, Sun, Cheng, Yu, Jian, Tang, Zhongzhi, Huang, Linxi, Ma, Biao, He, Zhijie, Zhou, Qingshan, Yu, Rongguo, Tong, Zhihui, and Li, Weiqin

Published
2022
Full Text
View/download PDF

8. Obstructive Fibrinous Tracheal Pseudomembrane Following Repeated Intratracheal Interventions

Author

Tang,Wei, Zhou,Wenlai, Zheng,Xiangde, Tang,Wei, Zhou,Wenlai, and Zheng,Xiangde

Abstract

Wei Tang, Wenlai Zhou,* Xiangde Zheng* Department of Critical Care Medicine, Dazhou Central Hospital, Dazhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Wenlai Zhou; Xiangde Zheng, Department of Critical Care Medicine, Dazhou Central Hospital, Dazhou, 635000, People’s Republic of China, Email Zhouwl1218@163.com; zxdfq123@163.comAbstract: Obstructive fibrinous tracheal pseudomembrane (OFTP) is a relatively rare complication of endotracheal intubation. Despite being well documented, the exact pathogenesis of OFTP remains unclear. Some studies suggest that it may arise from the early stage of ischemic tracheal wall injury caused by the cuff pressure during intubation. Diagnosis and treatment of OFTP can be facilitated through therapeutic bronchoscopy. In this case report, we describe a patient who presented with dyspnea following repeated intratracheal interventions and was diagnosed with OFTP. The patient was successfully treated with bronchoscopic cryotherapy and was subsequently discharged from the hospital.Keywords: pseudomembrane, OFTP, intratracheal interventions, intubation, dyspnea

Published
2024

12. Mechanism exploration of 6-Gingerol in the treatment of atherosclerosis based on network pharmacology, molecular docking and experimental validation

Author

Hu, Youdong, primary, Liu, Tingting, additional, Zheng, Guangzhen, additional, Zhou, Li, additional, Ma, Ke, additional, Xiong, Xiaolian, additional, Zheng, Cheng, additional, Li, Jin, additional, Zhu, Yong, additional, Bian, Wenhui, additional, Zheng, Xiangde, additional, Xiong, Qingping, additional, and Lin, Jiafeng, additional

Published
2023
Full Text
View/download PDF

13. Enteral nutrition feeding in Chinese intensive care units: a cross-sectional study involving 116 hospitals

Author

Xing, Juan, Zhang, Zhongheng, Ke, Lu, Zhou, Jing, Qin, Bingyu, Liang, Hongkai, Chen, Xiaomei, Liu, Wenming, Liu, Zhongmin, Ai, Yuhang, Wang, Difeng, Wang, Qiuhui, Zhou, Qingshan, Zhang, Fusen, Qian, Kejian, Jiang, Dongpo, Zang, Bin, Li, Yimin, Huang, Xiaobo, Qu, Yan, Xie, Yinguang, Xu, Donglin, Zou, Zhiqiang, Zheng, Xiangde, Liu, Jianbo, Guo, Feng, Liang, Yafeng, Sun, Qiang, Gao, Hongmei, Liu, Yang, Chang, Ping, Ceng, Aibin, Yang, Rongli, Yao, Gaiqi, Sun, Yun, Wang, Xiaorong, Zhang, Yi, Wen, Yichao, Yu, Jian, Sun, Rongqing, Li, Zhiwei, Yuan, Shiying, Song, Yunlin, Gao, Peiyang, Liu, Haiyan, Zhang, Zhaohui, Wu, Yunfu, Ma, Biao, Guo, Qiang, Shan, Feng, Yang, Mingshi, Li, Hailing, Li, Yuanfei, Lu, Weihua, Wang, Lei, Qian, Chuangyun, Wang, Zhiyong, Lin, Jiandong, Zhang, Rumin, Wan, Peng, Peng, Zhiyong, Gong, Yuqiang, Huang, Linxi, Wu, Guobao, Sun, Jie, Deng, Yijun, Shi, Dongwu, Zhou, Lixin, Zhou, Fachun, Shi, Qindong, Guo, Xiaodong, Liu, Xueyan, Wu, Weidong, Meng, Xiangzhong, Li, Liandi, Chen, Weiwei, Li, Shusheng, Wan, Xianyao, Chao, Zhixin, Zhang, An, Gu, Liming, Chen, Wei, Wu, Jinglan, Zhou, Lihua, Zhang, Zhenhuan, Weng, Yibing, Feng, Yongshun, Yang, Chunli, Feng, Yongjian, Zhao, Sumin, Tong, Fei, Hao, Dong, Han, Hui, Fu, Baocai, Gong, Chuanyong, Li, Zhiping, Hu, Kunlin, Kou, Qiuye, Zhang, Han, Liu, Jie, Fan, Chuming, Zhou, Xin, Chen, Xiumei, Sun, Junli, Zhou, Xuejun, Song, Bin, Sun, Cheng, Zhao, Liyun, Dong, Xinglu, Zhang, Linlin, Tong, Dafei, Pan, Zhiguo, Cai, Chuangjie, Wang, Donghao, Dong, Yingjun, Gong, Yuanqi, Wu, Zhisong, Meng, Xinke, Wang, Ping, and Li, Weiqin

Published
2018
Full Text
View/download PDF

14. Actively implementing an evidence-based feeding guideline for critically ill patients (NEED): a multicenter, cluster-randomized, controlled trial (vol 26, 46, 2022)

Author

Ke, Lu, Lin, Jiajia, Doig, Gordon S, van Zanten, Arthur RH, Wang, Yang, Xing, Juan, Zhang, Zhongheng, Chen, Tao, Zhou, Lixin, Jiang, Dongpo, Shi, Qindong, Lin, Jiandong, Liu, Jun, Cheng, Aibin, Liang, Yafeng, Gao, Peiyang, Sun, Junli, Liu, Wenming, Yang, Zhenyu, Zhang, Rumin, Xing, Wei, Zhang, An, Zhou, Zhigang, Zhou, Tingfa, Liu, Yang, Tong, Fei, Wang, Qiuhui, Pan, Aijun, Huang, Xiaobo, Fan, Chuming, Lu, Weihua, Shi, Dongwu, Wang, Lei, Li, Wei, Gu, Liming, Xie, Yingguang, Sun, Rongqing, Guo, Feng, Han, Lin, Zhou, Lihua, Zheng, Xiangde, Shan, Feng, Liu, Jianbo, Ai, Yuhang, Qu, Yan, Li, Liandi, Li, Hailing, Pan, Zhiguo, Xu, Donglin, Zou, Zhiqiang, Gao, Yan, Yang, Chunli, Kou, Qiuye, Zhang, Xijing, Wu, Jinglan, Qian, Chuanyun, Zhang, Weixing, Zhang, Minjie, Zong, Yuan, Qin, Bingyu, Zhang, Fusen, Zhai, Zhe, Sun, Yun, Chang, Ping, Yu, Bo, Yu, Min, Yuan, Shiying, Deng, Yijun, Zhao, Liyun, Zang, Bin, Li, Yuanfei, Zhou, Fachun, Chen, Xiaomei, Shao, Min, Wu, Weidong, Wu, Ming, Zhang, Zhaohui, Li, Yimin, Guo, Qiang, Wang, Zhiyong, Gong, Yuanqi, Song, Yunlin, Qian, Kejian, Feng, Yongjian, Fu, Baocai, Liu, Xueyan, Li, Zhiping, Gong, Chuanyong, Sun, Cheng, Yu, Jian, Tang, Zhongzhi, Huang, Linxi, Ma, Biao, He, Zhijie, Zhou, Qingshan, Yu, Rongguo, Tong, Zhihui, Li, Weiqin, and Trials, Chinese Critical Care Nutr

Published
2022

15. Additional file 1 of Actively implementing an evidence-based feeding guideline for critically ill patients (NEED): a multicenter, cluster-randomized, controlled trial

Author

Ke, Lu, Lin, Jiajia, Doig, Gordon S., van Zanten, Arthur R. H., Wang, Yang, Xing, Juan, Zhang, Zhongheng, Chen, Tao, Zhou, Lixin, Jiang, Dongpo, Shi, Qindong, Lin, Jiandong, Liu, Jun, Cheng, Aibin, Liang, Yafeng, Gao, Peiyang, Sun, Junli, Liu, Wenming, Yang, Zhenyu, Zhang, Rumin, Xing, Wei, Zhang, An, Zhou, Zhigang, Zhou, Tingfa, Liu, Yang, Tong, Fei, Wang, Qiuhui, Pan, Aijun, Huang, Xiaobo, Fan, Chuming, Lu, Weihua, Shi, Dongwu, Wang, Lei, Li, Wei, Gu, Liming, Xie, Yingguang, Sun, Rongqing, Guo, Feng, Han, Lin, Zhou, Lihua, Zheng, Xiangde, Shan, Feng, Liu, Jianbo, Ai, Yuhang, Qu, Yan, Li, Liandi, Li, Hailing, Pan, Zhiguo, Xu, Donglin, Zou, Zhiqiang, Gao, Yan, Yang, Chunli, Kou, Qiuye, Zhang, Xijing, Wu, Jinglan, Qian, Chuanyun, Zhang, Weixing, Zhang, Minjie, Zong, Yuan, Qin, Bingyu, Zhang, Fusen, Zhai, Zhe, Sun, Yun, Chang, Ping, Yu, Bo, Yu, Min, Yuan, Shiying, Deng, Yijun, Zhao, Liyun, Zang, Bin, Li, Yuanfei, Zhou, Fachun, Chen, Xiaomei, Shao, Min, Wu, Weidong, Wu, Ming, Zhang, Zhaohui, Li, Yimin, Guo, Qiang, Wang, Zhiyong, Gong, Yuanqi, Song, Yunlin, Qian, Kejian, Feng, Yongjian, Fu, Baocai, Liu, Xueyan, Li, Zhiping, Gong, Chuanyong, Sun, Cheng, Yu, Jian, Tang, Zhongzhi, Huang, Linxi, Ma, Biao, He, Zhijie, Zhou, Qingshan, Yu, Rongguo, Tong, Zhihui, and Li, Weiqin

Subjects
Data_FILES
Abstract

Additional file 1. Protocol and Statistical Analysis Plan.

Published
2022
Full Text
View/download PDF

16. Additional file 2 of Actively implementing an evidence-based feeding guideline for critically ill patients (NEED): a multicenter, cluster-randomized, controlled trial

Author

Ke, Lu, Lin, Jiajia, Doig, Gordon S., van Zanten, Arthur R. H., Wang, Yang, Xing, Juan, Zhang, Zhongheng, Chen, Tao, Zhou, Lixin, Jiang, Dongpo, Shi, Qindong, Lin, Jiandong, Liu, Jun, Cheng, Aibin, Liang, Yafeng, Gao, Peiyang, Sun, Junli, Liu, Wenming, Yang, Zhenyu, Zhang, Rumin, Xing, Wei, Zhang, An, Zhou, Zhigang, Zhou, Tingfa, Liu, Yang, Tong, Fei, Wang, Qiuhui, Pan, Aijun, Huang, Xiaobo, Fan, Chuming, Lu, Weihua, Shi, Dongwu, Wang, Lei, Li, Wei, Gu, Liming, Xie, Yingguang, Sun, Rongqing, Guo, Feng, Han, Lin, Zhou, Lihua, Zheng, Xiangde, Shan, Feng, Liu, Jianbo, Ai, Yuhang, Qu, Yan, Li, Liandi, Li, Hailing, Pan, Zhiguo, Xu, Donglin, Zou, Zhiqiang, Gao, Yan, Yang, Chunli, Kou, Qiuye, Zhang, Xijing, Wu, Jinglan, Qian, Chuanyun, Zhang, Weixing, Zhang, Minjie, Zong, Yuan, Qin, Bingyu, Zhang, Fusen, Zhai, Zhe, Sun, Yun, Chang, Ping, Yu, Bo, Yu, Min, Yuan, Shiying, Deng, Yijun, Zhao, Liyun, Zang, Bin, Li, Yuanfei, Zhou, Fachun, Chen, Xiaomei, Shao, Min, Wu, Weidong, Wu, Ming, Zhang, Zhaohui, Li, Yimin, Guo, Qiang, Wang, Zhiyong, Gong, Yuanqi, Song, Yunlin, Qian, Kejian, Feng, Yongjian, Fu, Baocai, Liu, Xueyan, Li, Zhiping, Gong, Chuanyong, Sun, Cheng, Yu, Jian, Tang, Zhongzhi, Huang, Linxi, Ma, Biao, He, Zhijie, Zhou, Qingshan, Yu, Rongguo, Tong, Zhihui, and Li, Weiqin

Abstract

Additional file 2. Table S1. Feeding intolerance score. Table S2. Recruitment of patients. Table S3. Proportion of patients receiving enteral and/or parenteral nutrition. Table S4. Proportion of patients receiving enteral nutrition. Table S5. Proportion of patients receiving parenteral nutrition. Table S6. Proportion of enteral nutrition delivered energy in daily energy delivery. Table S7. Target-reaching rate in fed patients from day1 to day7 after enrollment. Table S8. Protein intake from day1 to day7 after enrollment. Table S9. Organ failure-related outcomes. Figure S1. Proportion of enteral nutrition delivered energy in daily energy delivery within the first seven days after enrollment. Figure S2. Target-reaching (more than 70% of the estimated energy target) rate in fed patients for energy delivery from day1 to day7 after enrollment. Figure S3. Daily protein intake from day1 to day7 after enrollment.

Published
2022
Full Text
View/download PDF

17. Additional file 3 of Actively implementing an evidence-based feeding guideline for critically ill patients (NEED): a multicenter, cluster-randomized, controlled trial

Author

Ke, Lu, Lin, Jiajia, Doig, Gordon S., van Zanten, Arthur R. H., Wang, Yang, Xing, Juan, Zhang, Zhongheng, Chen, Tao, Zhou, Lixin, Jiang, Dongpo, Shi, Qindong, Lin, Jiandong, Liu, Jun, Cheng, Aibin, Liang, Yafeng, Gao, Peiyang, Sun, Junli, Liu, Wenming, Yang, Zhenyu, Zhang, Rumin, Xing, Wei, Zhang, An, Zhou, Zhigang, Zhou, Tingfa, Liu, Yang, Tong, Fei, Wang, Qiuhui, Pan, Aijun, Huang, Xiaobo, Fan, Chuming, Lu, Weihua, Shi, Dongwu, Wang, Lei, Li, Wei, Gu, Liming, Xie, Yingguang, Sun, Rongqing, Guo, Feng, Han, Lin, Zhou, Lihua, Zheng, Xiangde, Shan, Feng, Liu, Jianbo, Ai, Yuhang, Qu, Yan, Li, Liandi, Li, Hailing, Pan, Zhiguo, Xu, Donglin, Zou, Zhiqiang, Gao, Yan, Yang, Chunli, Kou, Qiuye, Zhang, Xijing, Wu, Jinglan, Qian, Chuanyun, Zhang, Weixing, Zhang, Minjie, Zong, Yuan, Qin, Bingyu, Zhang, Fusen, Zhai, Zhe, Sun, Yun, Chang, Ping, Yu, Bo, Yu, Min, Yuan, Shiying, Deng, Yijun, Zhao, Liyun, Zang, Bin, Li, Yuanfei, Zhou, Fachun, Chen, Xiaomei, Shao, Min, Wu, Weidong, Wu, Ming, Zhang, Zhaohui, Li, Yimin, Guo, Qiang, Wang, Zhiyong, Gong, Yuanqi, Song, Yunlin, Qian, Kejian, Feng, Yongjian, Fu, Baocai, Liu, Xueyan, Li, Zhiping, Gong, Chuanyong, Sun, Cheng, Yu, Jian, Tang, Zhongzhi, Huang, Linxi, Ma, Biao, He, Zhijie, Zhou, Qingshan, Yu, Rongguo, Tong, Zhihui, and Li, Weiqin

Subjects
health care facilities, manpower, and services
Abstract

Additional file 3. Continued Table 1. Baseline ICU and Patient-Level Characteristics..

Published
2022
Full Text
View/download PDF

22. Active Implementation of an Evidence-Based Nutrition Guideline for Critically Ill Patients Versus Standard Care: A Cluster Randomised, Multicentre, Controlled Trial

Author

Ke, Lu, primary, Lin, Jiajia, additional, Doig, Gordon S., additional, van Zanten, Arthur R.H., additional, Wang, Yang, additional, Xing, Juang, additional, Zhang, Zhongheng, additional, Chen, Tao, additional, Zhou, Lixin, additional, Jiang, Dongpo, additional, Shi, Qindong, additional, Lin, Jiandong, additional, Liu, Jun, additional, Cheng, Aibin, additional, Liang, Yafeng, additional, Gao, Peiyang, additional, Sun, Junli, additional, Liu, Wenming, additional, Yang, Zhenyu, additional, Zhang, Rumin, additional, Xing, Wei, additional, Zhang, An, additional, Zhou, Zhigang, additional, Zhou, Tingfa, additional, Liu, Yang, additional, Tong, Fei, additional, Wang, Qiuhui, additional, Pan, Aijun, additional, Huang, Xiaobo, additional, Fan, Chuming, additional, Lu, Weihua, additional, Shi, Dongwu, additional, Wang, Lei, additional, Li, Wei, additional, Gu, Liming, additional, Xie, Yingguang, additional, Sun, Rongqing, additional, Guo, Feng, additional, Han, Lin, additional, Zhou, Lihua, additional, Zheng, Xiangde, additional, Shan, Feng, additional, Liu, Jianbo, additional, Ai, Yuhang, additional, Qu, Yan, additional, Li, Liandi, additional, Li, Hailing, additional, Pan, Zhiguo, additional, Xu, Donglin, additional, Zou, Zhiqiang, additional, Gao, Yan, additional, Yang, Chunli, additional, Kou, Qiuye, additional, Zhang, Xijing, additional, Wu, Jinglan, additional, Qian, Chuanyun, additional, Zhang, Weixing, additional, Zhang, Minjie, additional, Zong, Yuan, additional, Qin, Bingyu, additional, Zhang, Fusen, additional, Zhai, Zhe, additional, Sun, Yun, additional, Chang, Ping, additional, Yu, Bo, additional, Yu, Min, additional, Yuan, Shiying, additional, Deng, YiJun, additional, Zhao, Liyun, additional, Zang, Bin, additional, Li, Yuanfei, additional, Zhou, Fachun, additional, Chen, Xiaomei, additional, Shao, Min, additional, Wu, Weidong, additional, Wu, Ming, additional, Zhang, Zhaohui, additional, Li, Yimin, additional, Guo, Qiang, additional, Wang, Zhiyong, additional, Gong, Yuanqi, additional, Song, Yunlin, additional, Qian, Kejian, additional, Feng, Yongjian, additional, Fu, Baocai, additional, Liu, Xueyan, additional, Li, Zhiping, additional, Gong, Chuanyong, additional, Sun, Cheng, additional, Yu, Jian, additional, Tang, Zhongzhi, additional, Huang, Linxi, additional, Ma, Biao, additional, He, Zhijie, additional, Zhou, Qingshan, additional, Yu, Rongguo, additional, Tong, Zhihui, additional, and Li, Weiqin, additional

Published
2021
Full Text
View/download PDF

26. The treatment and rehabilitation of a critical COVID‐19 case in China.

Author

Zheng, Xiangde, Tian, Lin, Liu, Qinggao, Li, Shilin, Zeng, Fanwei, and Zeng, Fanxin

Subjects
*COVID-19, *REHABILITATION, *SYMPTOMS, *DYSPNEA
Abstract

The lung lesions of this COVID‐19 patient were slowly absorbed, and the clinical symptoms with shortness of breath were improved slowly in the recovery period. [ABSTRACT FROM AUTHOR]

Published
2021
Full Text
View/download PDF

28. UNVEILING THE CAUSAL ASSOCIATION BETWEEN NONINFECTIOUS RESPIRATORY DISORDERS AND SEPSIS THROUGH MENDELIAN RANDOMIZATION ANALYSIS.

Author

Liu C, He L, and Zheng X

Subjects
Humans, Pulmonary Disease, Chronic Obstructive genetics, Pulmonary Disease, Chronic Obstructive complications, Asthma genetics, Asthma complications, Mendelian Randomization Analysis, Sepsis genetics, Sepsis complications, Genome-Wide Association Study
Abstract

Abstract: Background: The association between sepsis and noninfectious respiratory diseases is well-documented, yet the specific causal link between the two remains unclear. In order to explore this relationship further, we employed a Mendelian randomization (MR) analysis utilizing data from the UK Biobank and FinnGen Biobank. Methods: We analyzed the summary statistics of a genome-wide association study summary statistics for chronic obstructive pulmonary disease (COPD), asthma, pulmonary embolism (PE), idiopathic pulmonary fibrosis (IPF), obstructive sleep apnea (OSA), lung cancer, sepsis, and sepsis-related mortality. We employed the inverse-variance weighted (IVW) method and four additional MR methods. Heterogeneity and horizontal pleiotropy were assessed using the Cochrane's Q test, MR-Egger intercept, and MR-PRESSO test. A sensitivity analysis was also performed. Results: MR analysis showed associations between COPD and lung cancer with increased sepsis risk (odds ratio (OR)IVW 1.138, P = 0.006; (OR)IVW 1.123, P = 0.031; respectively) and sepsis mortality ((OR)IVW 1.350, P = 0.022; (OR)IVW 1.312, P = 0.022; respectively). Asthma exhibited a potential protective effect against sepsis mortality ((OR)IVW = 0.300, P = 0.039), while PE demonstrated a risk effect ((OR)IVW = 1.148, P = 0.032). No causal association was observed between asthma, PE, and sepsis ( P > 0.05). IPF and OSA were not significantly associated with sepsis or sepsis-related mortality ( P > 0.05). Heterogeneity and horizontal pleiotropy were not evident for asthma or lung cancer ( P > 0.05). However, horizontal pleiotropy was suggested for COPD by the MR-Egger regression ( P < 0.05), but not by the MR-PRESSO test ( P > 0.05). IPF and OSA were not significantly associated with sepsis or sepsis-related mortality ( P > 0.05). Conclusion: Our MR analysis offers new insights into potential links between noninfectious respiratory diseases and the risk of sepsis. However, additional investigation into the underlying mechanisms and clinical studies are necessary to confirm these findings., Competing Interests: The authors report no conflicts of interest., (Copyright © 2024 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the Shock Society.)

Published
2024
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results