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201 results on '"Zheng, Qingfeng"'

1. Conversion chemoradiotherapy combined with nab-paclitaxel plus cisplatin in patients with locally advanced borderline-resectable or unresectable esophageal squamous cell carcinoma: a phase i/ii prospective cohort study

Author

Yu, Nuo, Chen, Xiankai, Li, Jiao, Kang, Xiaozheng, Wang, Zhen, Zhang, Ruixiang, Qin, Jianjun, Li, Yong, Zheng, Qingfeng, Feng, Guojie, Deng, Lei, Zhang, Tao, Wang, Wenqing, Liu, Wenyang, Wang, Jianyang, Feng, Qinfu, Lv, Jima, Zhou, Zongmei, Xiao, Zefen, Bi, Nan, Li, Yin, and Wang, Xin

Published
2024
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8. Evaluation of competitiveness of Foshan ceramic industry and selection of promotion path

Author

Zheng, Qingfeng, Xu, Hui, Xu, Xiaoya, Li, Kan, Editor-in-Chief, Li, Qingyong, Associate Editor, Fournier-Viger, Philippe, Series Editor, Hong, Wei-Chiang, Series Editor, Liang, Xun, Series Editor, Wang, Long, Series Editor, Xu, Xuesong, Series Editor, Fernández-Viagas, Víctor, editor, Kandel, Bijay Kumar, editor, Valmohammadi, Changiz, editor, and Mallick, Hrushikesh, editor

Published
2023
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13. Evaluation and projection of circulation conditions tied to summertime compound drought and heatwave frequency over the Yangtze River Delta, China, for the carbon neutrality period based on CMIP6 GCMs.

Author

Wang, Jing, Liang, Ping, Cheng, Fei, Liu, Yanju, Song, Chengyu, Wu, Wei, Zheng, Qingfeng, Zhang, Tianyu, Qu, Ping, Li, Yujie, and Ding, Yihui

Subjects
CARBON offsetting, HEAT waves (Meteorology), CLIMATE change models, SUMMER
Abstract

Frequent occurrences of compound droughts and heatwaves (CDHWs) may have considerable adverse impacts on human health and socioeconomic development. To project future summertime CDHWs over the Yangtze River Delta (YRD) of China under carbon neutrality (CN) for policymakers, we used nine global climate models (GCMs) from the Coupled Model Intercomparison Project Phase 6 (CMIP6) and evaluated and projected circulation conditions tied to the summer YRD CDHW frequency in the boreal summer. The results show that a marked mid‐tropospheric regional‐scale anticyclonic anomaly centred over the East China Sea can be deemed the dominant system linking the more frequent occurrence of YRD CDHWs. Our selected nine CMIP6 GCMs better captured the observed climatological and anomalous spatial circulation patterns connected to the summer YRD CDHW frequency. Moreover, the nine models' multi‐model ensemble mean (9MME) was better than most of the individual models regarding the related climatological circulation simulations. The 9MME‐projected changes in circulation conditions tied to summer YRD CDHWs during the carbon neutrality period (2050–2060) under SSP119 favour the comparable occurrence of the YRD with that for the same period under the medium greenhouse gas (GHG) warming scenario (SSP245), but the intensities of the CDHWs are the least severe. However, the highest number of YRD CDHWs is driven by the high GHG warming scenario (SSP585), and these CDHWs feature the most severe intensity. Our research identified a new paradigm regarding the frequency and intensity of the summer YRD CDHW under SSP119, highlighting the potential role of the newly accessible CN‐oriented sustainable development pathway in alleviating compound extremes. [ABSTRACT FROM AUTHOR]

Published
2024
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14. Effectiveness and safety of camrelizumab-containing neoadjuvant therapy in patients with esophageal squamous cell carcinoma: a prospective multicenter observational cohort study

Author

Zhang, Yi, primary, Shen, Guoyi, additional, Xu, Rongyu, additional, Huang, Guozhong, additional, Huang, Zhijun, additional, Duan, Hongbing, additional, Yang, Shengsheng, additional, Zheng, Qingfeng, additional, Yang, Libao, additional, Liu, Rongxing, additional, Ma, Liangyun, additional, Chen, Shaogeng, additional, Yi, Yunfeng, additional, Zhang, Zheming, additional, Li, Kezhi, additional, Birdas, Thomas J., additional, Koyanagi, Kazuo, additional, and Simone II, Charles B., additional

Published
2023
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17. Identification of lymphophilic subtype in resectable esophageal squamous cell carcinoma using genetic signatures from large-scale genomic repertoires

Author

Li, Yin, primary, Kang, Xiaozheng, additional, Wan, Zhiyi, additional, Zhang, Ruixiang, additional, Zhang, Enli, additional, Wang, Zhen, additional, Zheng, Qingfeng, additional, Chen, Xiankai, additional, Li, Yong, additional, Qin, Jianjun, additional, Xue, Qi, additional, Gao, Shugeng, additional, and He, Jie, additional

Published
2023
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18. Comparison of neoadjuvant nab‐paclitaxel plus immunotherapy versus paclitaxel plus immunotherapy for esophageal squamous cell carcinoma

Author

Yang, Yafan, primary, Li, Haomiao, additional, Chen, Xiankai, additional, Qin, Jianjun, additional, Li, Yong, additional, Shen, Yaxing, additional, Zhang, Ruixiang, additional, Kang, Xiaozheng, additional, Wang, Zhen, additional, Zheng, Qingfeng, additional, Luo, Peng, additional, Li, Yin, additional, and He, Jie, additional

Published
2023
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25. The association between air pollution and the daily hospital visits for atrial fibrillation recorded by ECG: a cross-sectional study.

Author

Han, Jiming, Zhang, Rui, Guo, Jingyi, Zheng, Qingfeng, Chen, Xin, Wu, Shanmei, Tan, Jianguo, and Li, Yongguang

Subjects
AIR pollution, ATRIAL fibrillation, AIR pollutants, ELECTROCARDIOGRAPHY, CROSS-sectional method
Abstract

Background: The relationship between air pollution and atrial fibrillation (AF) recorded by electrocardiograph (ECG) has not yet been illustrated which worsens AF precaution and treatment. This research evaluated the association between air pollution and daily hospital visits for AF with ECG records. Methods: The study enrolled 4933 male and 5392 female patients whose ECG reports indicated AF from 2015 to 2018 in our hospital. Such data were then matched with meteorological data, including air pollutant concentrations, collected by local weather stations. A case-crossover study was performed to assess the relationship between air pollutants and daily hospital visits for AF recorded by ECG and to investigate its lag effect. Results: Our analysis revealed statistically significant associations between AF occurrence and demographic data, including age and gender. This effect was stronger in female (k = 0.02635, p < 0.01) and in patients over 65 y (k = 0.04732, p < 0.01). We also observed a hysteretic effect that when exposed to higher nitrogen dioxide(NO2), counting AF cases recorded by ECG may elevate at lag 0 with a maximum odds ratio(OR) of 1.038 (95% CI 1.014–1.063), on the contrary, O3 reduced the risk of daily visits for AF and its maximum OR was at lag 2, and the OR value was 0.9869 (95% CI 0.9791–0.9948). Other air pollutants such as PM2.5, PM10, and SO2 showed no clear relationship with the recorded AF. Conclusion: The associations between air pollution and AF recorded with ECG were preliminarily discovered. Short-term exposure to NO2 was significantly associated with daily hospital visits for AF management. [ABSTRACT FROM AUTHOR]

Published
2023
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26. Combined Modification of Urbanization and Monsoon in Meiyu Precipitation Changes in the Megacity Shanghai, China.

Author

Liang, Ping, Zhang, Zhiqi, Huang, Wenjuan, Zheng, Qingfeng, and Ma, Yue

Subjects
MEGALOPOLIS, MONSOONS, URBANIZATION, GLOBAL warming, WIND shear, URBAN growth, CITIES & towns
Abstract

The Meiyu season is a typical rainy season in East Asia that is controlled by summer monsoon. Despite extensive research on its impact, it is unclear how urbanization modifies precipitation during the Meiyu season in the background of the monsoon influence. To address this gap, this study investigated the effects of urbanization and monsoon on the modification of precipitation during the Meiyu season (PDM) in the megacity of Shanghai, China. Through homogenization analysis of the original observational data, we assessed the temporal and spatial variation in PDM in Shanghai during two stages of urbanization. Our findings revealed that both total precipitation and extreme daily precipitation during the Meiyu season in Shanghai have significantly increased since 1961. The spatial heterogeneity of PDM has also enhanced during the rapid urban process that has occurred since 1986. The long-term trend of increasing precipitation in Shanghai showed a synchronous variation with the East Asian subtropical summer monsoon (EASM) in 1961–2021. Over the interannual time scale, the significant positive correlation between PDM and EASM during the slow urbanization period (Stage 1: 1961–1985) changed to a non-significant correlation during the rapid urbanization period (Stage 2: 1986–2021), which was associated with the enhanced convective precipitation in Shanghai during the Meiyu season. Urbanization induced more convective precipitation and further weakened the association between PDM and EASM over the central city and nearby areas during Stage 2. The rapid urbanization process also resulted in increased differences in near-surface wind between urban and non-urban areas, which facilitated more PDM over the central city due to the urban friction effect and wind shear in Stage 2. Furthermore, our analysis suggests that the increase in precipitation may be associated with the enhanced coupling of cold air intrusion with the warmer climate background due to the urban heat effect occurring in Stage 2. These findings contribute to a better understanding of how urbanization and monsoons affect PDM in East Asian megacities and serve as a unique reference for climate prediction in this region. [ABSTRACT FROM AUTHOR]

Published
2023
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31. Real-world effectiveness and safety of camrelizumab-based neoadjuvant therapy in resectable esophageal cancer: Initial results of a prospective multicenter observational study.

Author

Zhang, Yi, primary, Shen, Guoyi, additional, Xu, Rongyu, additional, Huang, Guozhong, additional, Yang, Shengsheng, additional, Zheng, Qingfeng, additional, Huang, Zhijun, additional, Duan, Hongbing, additional, Ma, Liangyun, additional, Yang, Libao, additional, Yi, Yunfeng, additional, Liu, Rongxing, additional, Li, Kezhi, additional, and Chen, Shaogeng, additional

Published
2022
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34. 2021 NCC/CATS/CSTCVS/STM expert consensus on perioperative immunotherapy for esophageal cancer

Author

Kang, Xiaozheng, primary, Qin, Jianjun, additional, Zhang, Ruixiang, additional, Wang, Zhen, additional, Zheng, Qingfeng, additional, Li, Yong, additional, Xu, Jianping, additional, Huang, Jing, additional, Wang, Xin, additional, Hui, Zhouguang, additional, Xue, Liyan, additional, Mao, Yousheng, additional, Li, Yin, additional, He, Jie, additional, Chen, Chun, additional, Chen, Haiquan, additional, Chen, Ke-Neng, additional, Chen, Long-Qi, additional, Fu, Maoyong, additional, Fu, Junke, additional, Geng, Qing, additional, Gong, Taiqian, additional, Guo, Shiping, additional, Han, Yongtao, additional, He, Yi, additional, Hu, Jian, additional, Jiang, Hongjing, additional, Jiang, Jie, additional, Jiang, Yuequan, additional, Kang, Mingqiang, additional, Ma, Jianqun, additional, Ma, Shaohua, additional, Liao, Yongde, additional, Li, Hecheng, additional, Li, Shanqing, additional, Li, Zhigang, additional, Liu, Shuoyan, additional, Liu, Yang, additional, Qiao, Guibin, additional, Tan, Lijie, additional, Tian, Hui, additional, Zhao, Gaofeng, additional, Zhao, Jun, additional, Zheng, Shiying, additional, Zhou, Yongan, additional, Nilsson, Magnus, additional, Schlottmann, Francisco, additional, Rosati, Riccardo, additional, Stefano, Cascinu, additional, Chiu, Philip Wai-yan, additional, Newman, Neil B., additional, Hirahara, Noriyuki, additional, Kim, Dae Joon, additional, Mehta, Rutika, additional, Johung, Kimberly L., additional, Cecchini, Michael, additional, Lloyd, Shane, additional, and Meredith, Kenneth, additional

Published
2021
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35. Study Design and Data Analysis of Artificial Pancreas Device Systems with Closed-Loop Glucose-Sensing Insulin Delivery

Author

Shankara, Sravya B., Liu, Yujia, Zheng, Qingfeng, Guo, Jing, Wang, Guixia, and Zhang, Bo

Subjects
Article Subject
Abstract

Objective. The objective of this article is to provide a high-profile review and discussion on the study design and statistical analysis of pivotal clinical trials conducted to demonstrate the safety and effectiveness of closed-loop investigational artificial pancreas device systems (APDSs) in premarket approval applications. Methods. The United States Food and Drug Administration (FDA) guidance on the content of investigational device exemption and premarket approval applications for APDSs is reviewed with special emphasis on study design and statistical analysis of the pivotal clinical trials. The two pivotal studies for the MiniMed 670G hybrid closed-loop system by Medtronic in their premarket approval application are summarized and discussed. Results. The United States FDA established detailed recommendations on the study design and statistical analysis of pivotal clinical trials for the industry that seek market investigational APDSs and for FDA scientific reviewers that regulate the device applications. The recommendations cover specifics regarding patient population, clinical endpoints, and strategies for data analysis. However, the two pivotal studies that demonstrated the effectiveness of the FDA-approved MiniMed 670G hybrid closed-loop system were not typical randomized controlled trials as per FDA recommendations. Conclusion. The development and regulation of investigational APDSs require careful and sophisticated clinical study designs and data analysis in premarket approval applications. The regulatory evaluation process of the APDSs is rather complicated since the devices consist of multiple components that collaboratively function to mimic human pancreases.

Published
2021
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36. An evaluation of treatments and survival rates for pancreatic adenocarcinoma through survival analysis with inverse probability of treatment weighting: a population-based study

Author

Wang, Suzhen, primary, Wang, Chen, additional, Shi, Fuyan, additional, Tao, Enxue, additional, Zhu, Gaopei, additional, Li, Juan, additional, Feng, Jianing, additional, Wang, Xiaoxuan, additional, Guo, Jing, additional, Zheng, Qingfeng, additional, and Zhang, Bo, additional

Published
2021
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38. Raman spectroscopy as a potential diagnostic tool to analyse biochemical alterations in lung cancer

Author

Zheng, Qingfeng, Li, Junyi, Yang, Lin, Zheng, Bo, Wang, Jiangcai, Lv, Ning, Luo, Jianbin, Martin, Francis L, Liu, Dameng, He, Jie, Zheng, Qingfeng, Li, Junyi, Yang, Lin, Zheng, Bo, Wang, Jiangcai, Lv, Ning, Luo, Jianbin, Martin, Francis L, Liu, Dameng, and He, Jie

Abstract

Patient survival remains poor even after diagnosis in lung cancer cases, and the molecular events resulting from lung cancer progression remain unclear. Raman spectroscopy could be used to noninvasively and accurately reveal the biochemical properties of biological tissues on the basis of their pathological status. This study aimed at probing biomolecular changes in lung cancer, using Raman spectroscopy as a potential diagnostic tool. Herein, biochemical alterations were evident in the Raman spectra (region of 600–1800 cm−1) in normal and cancerous lung tissues. The levels of saturated and unsaturated lipids and the protein-to-lipid, nucleic acid-to-lipid, and protein-to-nucleic acid ratios were significantly altered among malignant tissues compared to normal lung tissues. These biochemical alterations in tissues during neoplastic transformation have profound implications in not only the biochemical landscape of lung cancer progression but also cytopathological classification. Based on this spectroscopic approach, classification methods including k-nearest neighbour (kNN) and support vector machine (SVM) were successfully applied to cytopathologically diagnose lung cancer with an accuracy approaching 99%. The present results indicate that Raman spectroscopy is an excellent tool to biochemically interrogate and diagnose lung cancer.

Published
2020

39. Exploring the Dynamics of Hemorrhagic Fever with Renal Syndrome Incidence in East China Through Seasonal Autoregressive Integrated Moving Average Models

Author

Shi,Fuyan, Yu,Changlan, Yang,Liping, Li,Fangyou, Lun,Jiangtao, Gao,Wenfeng, Xu,Yongyong, Xiao,Yufei, Shankara,Sravya B, Zheng,Qingfeng, Zhang,Bo, Wang,Suzhen, Shi,Fuyan, Yu,Changlan, Yang,Liping, Li,Fangyou, Lun,Jiangtao, Gao,Wenfeng, Xu,Yongyong, Xiao,Yufei, Shankara,Sravya B, Zheng,Qingfeng, Zhang,Bo, and Wang,Suzhen

Abstract

Fuyan Shi,1 Changlan Yu,2 Liping Yang,3 Fangyou Li,2 Jiangtao Lun,4 Wenfeng Gao,5 Yongyong Xu,6 Yufei Xiao,1 Sravya B Shankara,7 Qingfeng Zheng,8 Bo Zhang,9 Suzhen Wang1 1Department of Health Statistics, School of Public Health and Management, Weifang Medical University, Weifang, Shandong, People’s Republic of China; 2Anqiu City Center for Disease Control and Prevention, Anqiu, Shandong, People’s Republic of China; 3Health and Medical Center, Xijing Hospital, Air Force Military Medical University, Xi’an, Shannxi, People’s Republic of China; 4Anqiu Meteorological Bureau, Anqiu, Shandong, People’s Republic of China; 5Department of Immunology and Rheumatology, Affiliated Hospital of Weifang Medical University, Weifang, Shandong, People’s Republic of China; 6Department of Health Statistics, School of Military Preventive Medicine, Air Force Military Medical University, Xi’an, Shannxi, People’s Republic of China; 7Program in Health: Science, Society, and Policy, Brandeis University, Waltham, MA, USA; 8Institute for Hospital Management of Tsinghua University, Tsinghua Campus, Shenzhen, People’s Republic of China; 9Department of Neurology and ICCTR Biostatistics and Research Design Center, Boston Children’s Hospital and Harvard Medical School, Boston, MA, USACorrespondence: Bo Zhang; Suzhen Wang Email bo.zhang@childrens.harvard.edu; wangsz@wfmc.edu.cnObjective: The purpose of this study was to explore the dynamics of incidence of hemorrhagic fever with renal syndrome (HFRS) from 2000 to 2017 in Anqiu City, a city located in East China, and find the potential factors leading to the incidence of HFRS.Methods: Monthly reported cases of HFRS and climatic data from 2000 to 2017 in the city were obtained. Seasonal autoregressive integrated moving average (SARIMA) models were used to fit the HFRS incidence and predict the epidemic trend in Anqiu City. Univariate and multivariate gen

Published
2020

42. Exploring the Dynamics of Hemorrhagic Fever with Renal Syndrome Incidence in East China Through Seasonal Autoregressive Integrated Moving Average Models

Author

Shi, Fuyan, primary, Yu, Changlan, additional, Yang, Liping, additional, Li, Fangyou, additional, Lun, Jiangtao, additional, Gao, Wenfeng, additional, Xu, Yongyong, additional, Xiao, Yufei, additional, Shankara, Sravya B, additional, Zheng, Qingfeng, additional, Zhang, Bo, additional, and Wang, Suzhen, additional

Published
2020
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