581 results on '"Zhaoping Liu"'
Search Results
2. Resurgence of syphilis: focusing on emerging clinical strategies and preclinical models
- Author
-
Shun Xiong, Zhaoping Liu, Xiaohong Zhang, Shaobin Huang, Xuan Ding, Jie Zhou, Jiangchen Yao, Weiwei Li, Shuangquan Liu, and Feijun Zhao
- Subjects
Syphilis ,Treponema pallidum ,Diagnosis ,Vaccine ,Drug resistance ,Models ,Medicine - Abstract
Abstract Syphilis, a sexually transmitted disease (STD) caused by Treponema pallidum (T. pallidum), has had a worldwide resurgence in recent years and remains a public health threat. As such, there has been a great deal of research into clinical strategies for the disease, including diagnostic biomarkers and possible strategies for treatment and prevention. Although serological testing remains the predominant laboratory diagnostic method for syphilis, it is worth noting that investigations pertaining to the DNA of T. pallidum, non-coding RNAs (ncRNAs), chemokines, and metabolites in peripheral blood, cerebrospinal fluid, and other bodily fluids have the potential to offer novel perspectives on the diagnosis of syphilis. In addition, the global spread of antibiotic resistance, such as macrolides and tetracyclines, has posed significant challenges for the treatment of syphilis. Fortunately, there is still no evidence of penicillin resistance. Hence, penicillin is the recommended course of treatment for syphilis, whereas doxycycline, tetracycline, ceftriaxone, and amoxicillin are viable alternative options. In recent years, efforts to discover a vaccine for syphilis have been reignited with better knowledge of the repertoire of T. pallidum outer membrane proteins (OMPs), which are the most probable syphilis vaccine candidates. However, research on therapeutic interventions and vaccine development for human subjects is limited due to practical and ethical considerations. Thus, the preclinical model is ideal for conducting research, and it plays an important role in clinical transformation. Different preclinical models have recently emerged, such as in vitro culture and mouse models, which will lay a solid foundation for clinical treatment and prevention of syphilis. This review aims to provide a comprehensive summary of the most recent syphilis tactics, including detection, drug resistance treatments, vaccine development, and preclinical models in clinical practice.
- Published
- 2023
- Full Text
- View/download PDF
3. Characterization of Food-Additive Titanium Dioxide and Dietary Exposure to Titanium Dioxide Nanoparticles among the Chinese Population
- Author
-
Yue Cao, Huali Wang, Chunlai Liang, Qing Liu, Tong Ou, Ling Yong, Xiao Xiao, Haixia Sui, Dingguo Jiang, Zhaoping Liu, Sheng Wei, and Yan Song
- Subjects
food-additive titanium dioxide ,nanoparticles ,characterization ,dietary exposure ,Chinese population ,Chemistry ,QD1-999 - Abstract
Titanium dioxide (TiO2) is a prevalent food additive, yet comprehensive data on particle size and dietary exposure are lacking in China. Transmission electron microscopy results revealed that the quantitative proportion of nanoparticles (NPs) in food-additive TiO2 was 37.7%, with a mass fraction of 9.89%. Laboratory test results showed that among the domestic products surveyed, candies excluding gum-based candies contained the highest content of TiO2. Using consumption data from the China Health and Nutrition Survey in 2018, the average dietary exposure for TiO2 and TiO2 NPs in the Chinese population were calculated at 34.84 and 3.44 μg/kg bw/day, respectively. The primary dietary sources were puffed food and powdered drinks. Exposure varied significantly across age and region, with children and Inner Mongolia residents having the highest intake. TiO2 NP exposure showed a negative correlation with age. Despite this, the dietary exposure risk of TiO2 NPs for the Chinese population remains deemed acceptable.
- Published
- 2024
- Full Text
- View/download PDF
4. Building a Layer-Structured Aluminum/Graphene Composite with Significant Improvement in Electrical Conductivity
- Author
-
Zishun Wang, Wenhui Li, Junliang Ma, Baishan Liu, Wei Wang, and Zhaoping Liu
- Subjects
graphene ,Al ,composite ,electrical conductivity ,Technology ,Electrical engineering. Electronics. Nuclear engineering ,TK1-9971 ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Microscopy ,QH201-278.5 ,Descriptive and experimental mechanics ,QC120-168.85 - Abstract
Aluminum (Al) and its alloys are widely used in various fields due to their excellent physical properties. Although many efforts have been made to fabricate an Al-based composite, they usually results in a significant decrease in electrical conductivity. Herein, a special layer-structured Al/graphene (Gr)/Al composite was successfully designed and fabricated through a facile method using the ultrasonic spraying of graphene powder with alumina removal and a subsequent vacuum hot-pressing process. The as-obtained Al/Gr/Al composite presents a significantly enhanced electrical conductivity of 66% IACS, which is much higher than that of other reported Al-based composites, while it still maintains similar mechanical properties. This work provides a new strategy for the development of highly conductive Al-based composites, which would be very useful and important for practical applications.
- Published
- 2024
- Full Text
- View/download PDF
5. High‐Nickel Heterostructured Cathodes with Local Stoichiometry Control for High‐Voltage Operation
- Author
-
Chong Yin, Mingyuan Ge, Youngmin Chung, Jianming Bai, Wah-Keat Lee, Kim Kisslinger, Steven N. Ehrlich, Xianghui Xiao, Bao Qiu, Stephen E. Trask, Alison R. Dunlop, Andrew N. Jansen, Zhaoping Liu, Youngho Shin, and Feng Wang
- Subjects
cycling stability ,high-nickel cathodes ,lithium-ion batteries ,local stoichiometry control ,thermal stability ,Physics ,QC1-999 ,Chemistry ,QD1-999 - Abstract
The growing demand for lithium‐ion batteries to power electric vehicles and other energy‐dense devices continues to fuel the need for cathodes of increasingly higher nickel in cathodes. The relentless pursuit of high Ni content, however, raises concerns on compromising cell lifetime and safety, especially under high‐voltage operation. Alternative to the traditional design of uniform or core–shell composition, we report a rational control of local stoichiometry in high‐Ni cathodes, enabling their high thermal and cycling stabilities—up to 258 °C at the fully charged state and 91.4% capacity retention for 100 cycles between 2.7 and 4.4 V. Multimodal synchrotron X‐ray characterization unveils the heterostructure of secondary particles, featuring a high‐Ni core (LiNi0.90Mn0.05Co0.05O2) covered by a thin Ni‐gradient layer that remains stable over prolonged cycling due to suppressed oxygen release and structural deterioration. This work underlines, the intricate interplay between local stoichiometry and redox reactions in stabilizing high‐Ni cathodes for high‐voltage operation while ensuring safety.
- Published
- 2023
- Full Text
- View/download PDF
6. Advancing food safety risk assessment in China: development of new approach methodologies (NAMs)
- Author
-
Daoyuan Yang, Hui Yang, Miaoying Shi, Xudong Jia, Haixia Sui, Zhaoping Liu, and Yongning Wu
- Subjects
next-generation risk assessment ,new approach methodologies ,China ,China National Center for Food Safety Risk Assessment ,food toxicology ,Toxicology. Poisons ,RA1190-1270 - Abstract
Novel techniques and methodologies are being developed to advance food safety risk assessment into the next-generation. Considering the shortcomings of traditional animal testing, new approach methodologies (NAMs) will be the main tools for the next-generation risk assessment (NGRA), using non-animal methodologies such as in vitro and in silico approaches. The United States Environmental Protection Agency and the European Food Safety Authority have established work plans to encourage the development and application of NAMs in NGRA. Currently, NAMs are more commonly used in research than in regulatory risk assessment. China is also developing NAMs for NGRA but without a comprehensive review of the current work. This review summarizes major NAM-related research articles from China and highlights the China National Center for Food Safety Risk Assessment (CFSA) as the primary institution leading the implementation of NAMs in NGRA in China. The projects of CFSA on NAMs such as the Food Toxicology Program and the strategies for implementing NAMs in NGRA are outlined. Key issues and recommendations, such as discipline development and team building, are also presented to promote NAMs development in China and worldwide.
- Published
- 2023
- Full Text
- View/download PDF
7. Kaempferol Improves Exercise Performance by Regulating Glucose Uptake, Mitochondrial Biogenesis, and Protein Synthesis via PI3K/AKT and MAPK Signaling Pathways
- Author
-
Xiaoning Ji, Chaozheng Zhang, Jing Yang, Yaru Tian, Lijuan You, Hui Yang, Yongning Li, Haibo Liu, Deng Pan, and Zhaoping Liu
- Subjects
kaempferol ,exercise performance ,mitochondria function ,glucose uptake ,protein synthesis ,Chemical technology ,TP1-1185 - Abstract
Kaempferol is a natural flavonoid with reported bioactivities found in many fruits, vegetables, and medicinal herbs. However, its effects on exercise performance and muscle metabolism remain inconclusive. The present study investigated kaempferol’s effects on improving exercise performance and potential mechanisms in vivo and in vitro. The grip strength, exhaustive running time, and distance of mice were increased in the high-dose kaempferol group (p < 0.01). Also, kaempferol reduced fatigue-related biochemical markers and increased the activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) related to antioxidant capacity. Kaempferol also increased the glycogen and adenosine triphosphate (ATP) content in the liver and skeletal muscle, as well as glucose in the blood. In vitro, kaempferol promoted glucose uptake, protein synthesis, and mitochondrial function and decreased oxidative stress in both 2D and 3D C2C12 myotube cultures. Moreover, kaempferol activated the PI3K/AKT and MAPK signaling pathways in the C2C12 cells. It also upregulated the key targets of glucose uptake, mitochondrial function, and protein synthesis. These findings suggest that kaempferol improves exercise performance and alleviates physical fatigue by increasing glucose uptake, mitochondrial biogenesis, and protein synthesis and by decreasing ROS. Kaempferol’s molecular mechanism may be related to the regulation of the PI3K/AKT and MAPK signaling pathways.
- Published
- 2024
- Full Text
- View/download PDF
8. Next-generation cathode materials for ultrahigh-energy batteries
- Author
-
Bao Qiu, Yu Qiao, Biao Li, and Zhaoping Liu
- Subjects
Technology - Published
- 2023
- Full Text
- View/download PDF
9. Facile fabrication of layer-structured graphene/copper composite with enhanced electrical and mechanical properties
- Author
-
Wenhui Li, Junliang Ma, Baishan Liu, Wei Wang, and Zhaoping Liu
- Subjects
graphene ,Cu ,composite ,strengthening mechanism ,Materials of engineering and construction. Mechanics of materials ,TA401-492 ,Chemical technology ,TP1-1185 - Abstract
Copper (Cu) and its related composites are widely used and hence extremely important in industrial applications. Much efforts have been made to improve the physical properties of Cu, but usually lead to degradation of electrical performance. Herein, this work develops a facile way to fabricate layer-structured graphene/copper composite using graphene powder sprayed on Cu foil as building blocks. Compared to pure Cu bulk, significant improvement of both the electrical conductivity of 105.12% IACS and also ∼17% enhanced tensile strength is achieved. This strategy provides a versatile way to produce high-performance Cu composite in large with low cost for practical applications.
- Published
- 2024
- Full Text
- View/download PDF
10. LncRNA BC200/miR-150-5p/MYB positive feedback loop promotes the malignant proliferation of myelodysplastic syndrome
- Author
-
Zhaoping Liu, Pan Wang, Shunling Yuan, Yanyan Wang, Pengfei Cao, Feng Wen, Hui Li, Lin Zhu, Long Liang, Zi Wang, Bin Hu, Fuxiang Zheng, Jing Liu, Xiaojuan Xiao, and Ji Zhang
- Subjects
Cytology ,QH573-671 - Abstract
Abstract Myelodysplastic syndrome (MDS) is a group of heterogeneous hematologic malignancies with a risk of transformation to acute myeloid leukemia. Understanding the molecular mechanisms of the specific roles of long noncoding RNAs (lncRNAs) in MDS would create novel ways to identify diagnostic and therapeutic targets. The lncRNA BC200 is upregulated and acts as an oncogene in various cancers; however, its expression, clinical significance, and roles in MDS remain unclear. Here, we found that BC200 was highly expressed in MDS patients compared with normal individuals. Knockdown of BC200 inhibited MDS cell proliferation, colony formation, and cell cycle progression in vitro and suppressed the growth and invasiveness of MDS cells in vivo. Mechanistic investigations revealed that BC200 functioned as a miRNA sponge to positively regulate the expression of MYB through sponging miR-150-5p and subsequently promoted malignant proliferation of MDS cells. Conversely, we found that BC200 was a direct transcriptional target of MYB, and knockdown of MYB abolished the oncogenic effect of BC200/miR-150-5p. Taken together, our results revealed that the BC200/miR-150-5p/MYB positive feedback loop promoted the proliferation of MDS cells and is expected to be a potential biomarker and therapeutic target in MDS.
- Published
- 2022
- Full Text
- View/download PDF
11. Intricate crosstalk between MYB and noncoding RNAs in cancer
- Author
-
Dingyu Hu, Wenjun Shao, Li Liu, Yanyan Wang, Shunling Yuan, Zhaoping Liu, Jing Liu, and Ji Zhang
- Subjects
MYB ,Noncoding RNAs ,LncRNAs ,MiRNAs ,Tumorigenesis ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 ,Cytology ,QH573-671 - Abstract
Abstract MYB is often overexpressed in malignant tumors and plays a carcinogenic role in the initiation and development of cancer. Deletion of the MYB regulatory C-terminal domain may be a driving mutation leading to tumorigenesis, therefore, different tumor mechanisms produce similar MYB proteins. As MYB is a transcription factor, priority has been given to identifying the genes that it regulates. All previous attention has been focused on protein-coding genes. However, an increasing number of studies have suggested that MYB can affect the complexity of cancer progression by regulating tumor-associated noncoding RNAs (ncRNAs), such as microRNAs, long-non-coding RNAs and circular RNAs. ncRNAs can regulate the expression of numerous downstream genes at the transcription, RNA processing and translation levels, thereby having various biological functions. Additionally, ncRNAs play important roles in regulating MYB expression. This review focuses on the intricate crosstalk between oncogenic MYB and ncRNAs, which play a pivotal role in tumorigenesis, including proliferation, apoptosis, angiogenesis, metastasis, senescence and drug resistance. In addition, we discuss therapeutic strategies for crosstalk between MYB and ncRNAs to prevent the occurrence and development of cancer.
- Published
- 2021
- Full Text
- View/download PDF
12. The consumption survey of condiments for restaurant customers in 7 provinces and cities of China
- Author
-
Shanyawen LI, Yujing ZHOU, Ling YONG, Xiao XIAO, Jianwen LI, Zhaoping LIU, Sheng WEI, Jing WU, and Yan SONG
- Subjects
condiments ,consumption survey ,restaurant customers ,Food processing and manufacture ,TP368-456 ,Nutrition. Foods and food supply ,TX341-641 - Abstract
Objective To explore the condiment consumption for restaurant customers in Chinese, and provide basic data for risk assessment of hazards and nutrients in condiment. Methods Weighing method and three-day record method were used to investigate the condiment usage of 126 restaurants in 7 provinces/cities of Beijing, Chongqing, Liaoning, Shandong, Guangdong, Jiangsu and Shaanxi. Meanwhile, the number of people eating in each restaurant every day was recorded to estimate the average consumption. Results The median consumption of condiments per person-time in Chinese restaurants was 3.52 g of salt and substitutes, 1.33 g of flavor enhancer and freshener, 3.63 g of vinegar, 5.18 g of soy sauce, 1.78 g of sauce and its products, 0.25 g of cooking wine and its products,1.54 g of spices, 3.64 g of compound condiments and 0.00 g of other condiments. The difference of condiments consumption among restaurant customers in each province and city was statistically significant(P
- Published
- 2021
- Full Text
- View/download PDF
13. Significant Enhanced Mechanical Properties of Suspended Graphene Film by Stacking Multilayer CVD Graphene Films
- Author
-
Binbin Xiao, Mengqing Yin, Wanfa Li, Lingyan Liang, Shixun Dai, Xiaohui Zhang, Wei Wang, and Zhaoping Liu
- Subjects
chemical vapor deposition ,suspended graphene film ,mechanical properties ,Mechanical engineering and machinery ,TJ1-1570 - Abstract
Suspended graphene film is of great significance for building high-performance electrical devices. However, fabricating large-area suspended graphene film with good mechanical properties is still a challenge, especially for the chemical vapor deposition (CVD)-grown graphene films. In this work, the mechanical properties of suspended CVD-grown graphene film are investigated systematically for the first time. It is found that monolayer graphene film is hard to maintain on circular holes with a diameter of tens of micrometers, which can be improved greatly by increasing the layer of graphene films. The mechanical properties of CVD-grown multilayer graphene films suspended on a circular hole with a diameter of 70 µm can be increased by 20%, and multilayer graphene films prepared by layer-layer stacking process can be increased by up to 400% for the same size. The corresponding mechanism was also discussed in detail, which might pave the way for building high-performance electrical devices based on high-strength suspended graphene film.
- Published
- 2023
- Full Text
- View/download PDF
14. Alkali-Etched NiCoAl-LDH with Improved Electrochemical Performance for Asymmetric Supercapacitors
- Author
-
Liyin Hou, Xufeng Zhou, Lina Kong, Zhipeng Ma, Li Su, Zhaoping Liu, and Guangjie Shao
- Subjects
LDH ,supercapacitor ,alkali etached ,cation vacancy ,Chemistry ,QD1-999 - Abstract
Hydrotalcite, first found in natural ores, has important applications in supercapacitors. NiCoAl-LDH, as a hydrotalcite-like compound with good crystallinity, is commonly synthesized by a hydrothermal method. Al3+ plays an important role in the crystallization of hydrotalcite and can provide stable trivalent cations, which is conducive to the formation of hydrotalcite. However, aluminum and its hydroxides are unstable in a strong alkaline electrolyte; therefore, a secondary alkali treatment is proposed in this work to produce cation vacancies. The hydrophilicity of the NiCoAl-OH surface with cation vacancy has been greatly improved, which is conducive to the wetting and infiltration of electrolyte in water-based supercapacitors. At the same time, cation vacancies generate a large number of defects as active sites for energy storage. As a result, the specific capacity of the NiCoAl-OH electrode after 10,000 cycles can be maintained at 94.1%, which is much better than the NiCoAl-LDH material of 74%.
- Published
- 2023
- Full Text
- View/download PDF
15. Electrochemical Atomic Force Microscopy Study on the Dynamic Evolution of Lithium Deposition
- Author
-
Xixiu Shi, Jingru Yang, Wenyang Wang, Zhaoping Liu, and Cai Shen
- Subjects
lithium metal ,lithium dendrite ,in situ EC-AFM ,lithium deposition schematic ,Technology ,Electrical engineering. Electronics. Nuclear engineering ,TK1-9971 ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Microscopy ,QH201-278.5 ,Descriptive and experimental mechanics ,QC120-168.85 - Abstract
Lithium metal is one of the most promising anode materials for lithium-ion batteries; however, lithium dendrite growth hinders its large-scale development. So far, the dendrite formation mechanism is unclear. Herein, the dynamic evolution of lithium deposition in etheryl-based and ethylene carbonate (EC)-based electrolytes was obtained by combining an in situ electrochemical atomic force microscope (EC-AFM) with an electrochemical workstation. Three growth modes of lithium particles are proposed: preferential, merged, and independent growth. In addition, a lithium deposition schematic is proposed to clearly describe the morphological changes in lithium deposition. This schematic shows the process of lithium deposition, thus providing a theoretical basis for solving the problem of lithium dendrite growth.
- Published
- 2023
- Full Text
- View/download PDF
16. Localized High-Concentration Electrolyte (LHCE) for Fast Charging Lithium-Ion Batteries
- Author
-
Jingru Yang, Xixiu Shi, Wenyang Wang, Zhaoping Liu, and Cai Shen
- Subjects
solid electrolyte interphase ,electrolytes ,localized high-concentration electrolyte ,fast charging ,lithium-ion batteries ,Production of electric energy or power. Powerplants. Central stations ,TK1001-1841 ,Industrial electrochemistry ,TP250-261 - Abstract
The solid electrolyte interphase (SEI) significantly influences the electrochemical performance of lithium-ion batteries. Traditional electrolytes, particularly ether electrolytes, make it challenging to form a stable SEI film, and the corresponding lithium-ion batteries frequently exhibit poor electrochemical performance. In this paper, we develop a stable SEI film to improve fast charging and cycle performance using a localized high concentration electrolyte (LHCE). A unique solvation sheath formed by the coordination of Li+, anion, and solvent in the LHCE caused the anion to migrate quickly to the surface of the graphite anode and decompose to form a LiF-rich SEI. A LHCE enabled the Li||C battery to maintain a capacity of 124 mAh g−1 at a rate of 5 C, and the capacity remained at 289 mAh g−1 after 150 cycles at a rate of 0.1 C, with a capacity retention rate of 73% and an average coulomb efficiency of about 99.8%, thus demonstrating excellent long-cycle performance. The LFP||Li battery capacity at a 5 C rate can also be maintained at 102 mAh g−1.
- Published
- 2023
- Full Text
- View/download PDF
17. Progress and challenge of food microbiological risk assessment in China
- Author
-
Li BAI, Yeru WANG, Yibaina WANG, Yan QI, Zhaoping LIU, and Xin’an JIAO
- Subjects
food microbiology ,risk assessment ,whole food chain ,new technology ,Food processing and manufacture ,TP368-456 ,Nutrition. Foods and food supply ,TX341-641 - Abstract
In the recent 10 years, China has carried out the construction of food safety risk assessment system including microbiological risk assessment (MRA) in accordance with the Food Safety Law, and has made significant progress in the work system and technical system of MRA, which has become an important basis for the risk assessment of foodborne pathogens in China. With the change of food supply chain in the global post epidemic era and the rapid development of new technologies as well as the increasing demand for the modernization of food safety management in China, it will become the main challenge for the construction of food MRA to build assessment model based on China’s dietary consumption behavior, improve the implementation ability and quality of risk assessment, and realize the application of modern technologies in risk assessment.
- Published
- 2020
- Full Text
- View/download PDF
18. Advance on risk assessment methods of multiple chemicals combined exposure and its enlightenment to the construction of relevant systems in China
- Author
-
Shanyawen LI, Zhaoping LIU, Sheng WEI, Jing WU, and Yan SONG
- Subjects
multiple chemicals ,combined exposure ,cumulative risk assessment ,risk assessment framework ,Food processing and manufacture ,TP368-456 ,Nutrition. Foods and food supply ,TX341-641 - Abstract
People in the real world are exposed to multiple chemicals via multiple routes and co-exposure to multiple agents may induce joint effects, which draws extensive attention from the international community. Regulations of many countries oblige risk assessors to conduct cumulative risk assessments based on their own guidelines, findings of which provide the basis for scientific decision-making. By analyzing the method and frameworks of international risk assessment models of multiple chemicals, this paper explores the establishment of a risk assessment framework of multiple chemicals combined exposure to in food in China.
- Published
- 2020
- Full Text
- View/download PDF
19. High mobility group box 1 (HMGB1): a pivotal regulator of hematopoietic malignancies
- Author
-
Shunling Yuan, Zhaoping Liu, Zhenru Xu, Jing Liu, and Ji Zhang
- Subjects
High mobility group box 1 (HMGB1) ,Hematopoietic stem cells (HSCs) ,Bone marrow (BM) microenvironment ,Inflammation ,Chemoresistance ,Diseases of the blood and blood-forming organs ,RC633-647.5 ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Abstract High mobility group box 1 (HMGB1) is a nonhistone chromatin-associated protein that has been widely reported to play a pivotal role in the pathogenesis of hematopoietic malignancies. As a representative damage-associated molecular pattern (DAMP), HMGB1 normally exists inside cells but can be secreted into the extracellular environment through passive or active release. Extracellular HMGB1 binds with several different receptors and interactors to mediate the proliferation, differentiation, mobilization, and senescence of hematopoietic stem cells (HSCs). HMGB1 is also involved in the formation of the inflammatory bone marrow (BM) microenvironment by activating proinflammatory signaling pathways. Moreover, HMGB1-dependent autophagy induces chemotherapy resistance in leukemia and multiple myeloma. In this review, we systematically summarize the emerging roles of HMGB1 in carcinogenesis, progression, prognosis, and potential clinical applications in different hematopoietic malignancies. In summary, targeting the regulation of HMGB1 activity in HSCs and the BM microenvironment is highly beneficial in the diagnosis and treatment of various hematopoietic malignancies.
- Published
- 2020
- Full Text
- View/download PDF
20. The effect of friction behavior on the migration of metal elements from stainless-steel articles for food contact
- Author
-
Jingjing PAN, Zhaoping LIU, Qian LU, Yu ZONG, Dan LI, Jianguo ZHENG, Haixia SUI, and Huaining ZHONG
- Subjects
food contact material ,frictional behavior ,stainless steel ,metals ,migration ,Food processing and manufacture ,TP368-456 ,Nutrition. Foods and food supply ,TX341-641 - Abstract
Objective To evaluate the effect of friction behavior on migration levels of metal elements from stainless-steel articles for food contact. Methods The migration levels of metal elements from used and new stainless-steel articles were compared according to GB 4806.9-2016 and Council of Europe Resolution CM/Res (2013) 9. The migration conditions were boiling in 4% acetic acid for 30 min followed by at room temperature for 24 h and soaking in 5 g/L citric acid at 100 ℃ for 2 h, respectively. Meanwhile, the impact of dynamic friction on migration were investigated on new stainless-steel articles, where the friction method were referred to the GB/T 32095.2-2015 standard. Migration of metal elements complied with the corresponding standard. Results Based on the European standard, migration of lead in the first migration test was above limit of quantitation (LOQ) in all five used stainless-steel articles after friction, but none in new ones. The quantification rate of chromium in the first migration test in 80% (4/5) of used stainless-steel articles were above LOQ after friction by GB 4806.9-2016 standard while were 20% (1/5) in new ones. The migration level of Cr was higher by GB 4806.9-2016 standard than by European resolution in single dynamic friction study. Results from the dynamic friction experiments indicated that the migration of Cr and Ni reached equilibrium after 3 times of friction. Conclusion The migration condition in GB 4806.9-2016 standard had stronger leaching ability for Cr from stainless-steel articles than that in European resolution. Friction behavior promoted corrosion and metal element migration of stainless steel. Long-term used stainless-steel products had higher lead and chromium migration than new products, but without safety risks.
- Published
- 2020
- Full Text
- View/download PDF
21. Quantitative risk model of hazardous chemicals in foodstuffs in computer system
- Author
-
Liang SU, Lei ZHANG, Pengcheng REN, Zhixing LI, Yanan WANG, Ceng CEN, Chen XU, Zhaoping LIU, and Pingping ZHOU
- Subjects
risk assessment ,food chemicals ,computer system ,food safety ,Food processing and manufacture ,TP368-456 ,Nutrition. Foods and food supply ,TX341-641 - Abstract
Objective To quickly and automatically evaluate the risk of hazardous chemical substances in food quickly and automatically. Methods Based on the Spring MVC framework, a quantitative assessment model of food chemicals was integrated and a visualization of the assessment result was provided. Results A set of food safety risk assessment software chemical hazard based on multi-source data fusion electronic. Conclusion The e-evaluation system described in this article had enabled the process and automation of a quantitative assessment model for the risk of food chemicals. It had also enabled the quantitative assessment model for food chemicals to be widely used in the business, thereby improving the efficiency of assessment.
- Published
- 2020
- Full Text
- View/download PDF
22. RISK21: risk analyzing tool on dietary exposure of phthalic acid esters
- Author
-
Huihui BAO, Weifeng MAO, Yan SONG, Zhaoping LIU, Haixia SUI, and Lei ZHANG
- Subjects
risk21 ,phthalic acid esters ,dietary exposure ,threshold of toxicological concern ,risk assessment ,Food processing and manufacture ,TP368-456 ,Nutrition. Foods and food supply ,TX341-641 - Abstract
Objective To analyze the risks of dietary exposure of diethylhexyl phthalate (DEHP), dibutyl phthalate (DBP), diisononyl phthalate (DINP), butylbenzyl phthalate (BBP), diisobutyl phthalate (DIBP), dimethyl phthalate (DMP) and diethyl phthalate (DEP) to 2-6 years children in China using RISK21, so as to provide risk management strategy for phthalic acid esters (PAEs). Methods RISK PLOT module was used to analyze and rank risks, with toxicity as Y-axis and exposure as X-axis and margin of exposure (MOE) and uncertainty factor as parameters. Matrix calculation was conducted, risks level and rank of 7 kinds of PAEs to 2-6 years children were illustrated by visualized graphs. TTC PLOT module was used to analyze risks of DMP, DEP and DIBP, which were lacking of toxicity data. Results RISK PLOT showed that the risks of 7 kinds of PAEs for general population located in the green area, which demonstrated that they had low risk to 2-6 years children, and the risks of high food consumption population ranked in descending order were DBP, DIBP, DEHP, DMP, DEP, DINP and BBP. TTC PLOT showed that the risks of DMP, DEP and DIBP were lower than the corresponding threshold of toxicological concern (TTC) that demonstrated low risks. Conclusion RISK21 framework and tools could be a very useful tool for risk assessment and further risk management, and low risks of dietary exposure of 7 kinds of PAEs to 2-6 years children in China by RISK21 analyzing.
- Published
- 2020
- Full Text
- View/download PDF
23. Growth of Low-Defect Nitrogen-Doped Graphene Film Using Condensation-Assisted Chemical Vapor Deposition Method
- Author
-
Zhichao Guo, Zhenya Ye, Mengqing Yin, Shixun Dai, Xiaohui Zhang, Wei Wang, and Zhaoping Liu
- Subjects
chemical vapor deposition ,nitrogen-doped graphene films ,condensation-assisted CVD ,Technology ,Electrical engineering. Electronics. Nuclear engineering ,TK1-9971 ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Microscopy ,QH201-278.5 ,Descriptive and experimental mechanics ,QC120-168.85 - Abstract
It is significantly important to modulate the electrical properties of graphene films through doping for building desired electronic devices. One of the effective doping methods is the chemical vapor deposition (CVD) of graphene films with heteroatom doping during the process, but this usually results in nitrogen-doped graphene with low doping levels, high defect density, and low carrier mobility. In this work, we developed a novel condensation-assisted CVD method for the synthesis of high-quality nitrogen-doped graphene (NG) films at low temperatures of 400 °C using solid 3,4,5-trichloropyridine as a carbon and nitrogen source. The condensation system was employed to reduce the volatilization of the solid source during the non-growth stage, which leads to a great improvement of quality of as-prepared NG films. Compared to the one synthesized using conventional CVD methods, the NG films synthesized using condensation-assisted CVD present extremely low defects with a ratio of from D- to G-peak intensity (ID/IG) in the Raman spectrum lower than 0.35. The corresponding total N content, graphitic nitrogen/total nitrogen ratio, and carrier mobility reach 3.2 at%, 67%, and 727 cm2V−1S−1, respectively. This improved condensation-assisted CVD method provides a facile and well-controlled approach for fabricating high-quality NG films, which would be very useful for building electronic devices with high electrical performance.
- Published
- 2023
- Full Text
- View/download PDF
24. Analysis of ceRNA networks and identification of potential drug targets for drug-resistant leukemia cell K562/ADR
- Author
-
Zhaoping Liu, Yanyan Wang, Zhenru Xu, Shunling Yuan, Yanglin Ou, Zeyu Luo, Feng Wen, Jing Liu, and Ji Zhang
- Subjects
Long non-coding RNA ,ceRNA network ,Drug resistance ,Bioinformatics ,Leukemia ,Medicine ,Biology (General) ,QH301-705.5 - Abstract
Background Drug resistance is the main obstacle in the treatment of leukemia. As a member of the competitive endogenous RNA (ceRNA) mechanism, underlying roles of lncRNA are rarely reported in drug-resistant leukemia cells. Methods The gene expression profiles of lncRNAs and mRNAs in doxorubicin-resistant K562/ADR and sensitive K562 cells were established by RNA sequencing (RNA-seq). Expression of differentially expressed lncRNAs (DElncRNAs) and DEmRNAs was validated by qRT-PCR. The potential biological functions of DElncRNAs targets were identified by GO and KEGG pathway enrichment analyses, and the lncRNA-miRNA-mRNA ceRNA network was further constructed. K562/ADR cells were transfected with CCDC26 and LINC01515 siRNAs to detect the mRNA levels of GLRX5 and DICER1, respectively. The cell survival rate after transfection was detected by CCK-8 assay. Results The ceRNA network was composed of 409 lncRNA-miRNA pairs and 306 miRNA-mRNA pairs based on 67 DElncRNAs, 58 DEmiRNAs and 192 DEmRNAs. Knockdown of CCDC26 and LINC01515 increased the sensitivity of K562/ADR cells to doxorubicin and significantly reduced the half-maximal inhibitory concentration (IC50) of doxorubicin. Furthermore, knockdown of GLRX5 and DICER1 increased the sensitivity of K562/ADR cells to doxorubicin and significantly reduced the IC50 of doxorubicin. Conclusions The ceRNA regulatory networks may play important roles in drug resistance of leukemia cells. CCDC26/miR-140-5p/GLRX5 and LINC01515/miR-425-5p/DICER1 may be potential targets for drug resistance in K562/ADR cells. This study provides a promising strategy to overcome drug resistance and deepens the understanding of the ceRNA regulatory mechanism related to drug resistance in CML cells.
- Published
- 2021
- Full Text
- View/download PDF
25. Analysis of individual and combined estrogenic effects of bisphenol, nonylphenol and diethylstilbestrol in immature rats with mathematical models
- Author
-
Weifeng Mao, Yan Song, Haixia Sui, Pei Cao, and Zhaoping Liu
- Subjects
Endocrine disrupting chemicals ,Combined effects ,Mixture toxicity ,Factorial analysis ,Concentration addition ,Public aspects of medicine ,RA1-1270 - Abstract
Abstract Background Traditional toxicological studies focus on individual compounds. However, this single-compound approach neglects the fact that the mixture exposed to human may act additively or synergistically to induce greater toxicity than the single compounds exposure due to their similarities in the mode of action and targets. Mixture effects can occur even when all mixture components are present at levels that individually do not produce observable effects. So the individual chemical effect thresholds do not necessarily protect against combination effects, an understanding of the rules governing the interactive effects in mixtures is needed. The aim of the study was to test and analyze the individual and combined estrogenic effects of a mixture of three endocrine disrupting chemicals (EDCs), bisphenol A (BPA), nonylphenol (NP) and diethylstilbestrol (DES) in immature rats with mathematical models. Method In the present study, the data of individual estrogenic effects of BPA, NP and DES were obtained in uterotrophic bioassay respectively, the reference points for BPA, NP and DES were derived from the dose-response ralationship by using the traditional no observed adverse effect (NOAEL) or lowest observed adverse effect level (LOAEL) methods, and the benchmark dose (BMD) method. Then LOAEL values and the benchmark dose lower confidence limit (BMDL10) of single EDCs as the dose design basis for the study of the combined action pattern. Mixed prediction models, the 3 × 2 factorial design model and the concentration addition (CA) model, were employed to analyze the combined estrogenic effect of the three EDCs. Results From the dose-response relationship of estrogenic effects of BPA, NP and DES in the model of the prepuberty rats, the BMDL10(NOAEL) of the estrogenic effects of BPA, NP and DES were 90(120) mg/kg body weight, 6 mg/kg body weight and 0.10(0.25) μg/kg body weight, and the LOAEL of the the estrogenic effects of three EDCs were 240 mg/kg body weight, 15 mg/kg body weight and 0.50 μg/kg body weight, respectively. At BMDL10 doses based on the CA concept and the factorial analysis, the mode of combined effects of the three EDCs were dose addition. Mixtures in LOAEL doses, NP and DES combined effects on rat uterine/body weight ratio indicates antagonistic based on the CA concept but additive based on the factorial analysis. Combined effects of other mixtures are all additive by using the two models. Conclusion Our results showed that CA model provide more accurate results than the factorial analysis, the mode of combined effects of the three EDCs were dose addition, except mixtures in LOAEL doses, NP and DES combined effects indicates antagonistic effects based on the CA model but additive based on the factorial analysis. In particular, BPA and NP produced combination effects that are larger than the effect of each mixture component applied separately at BMDL doses, which show that additivity is important in the assessment of chemicals with estrogenic effects. The use of BMDL as point of departure in risk assessment may lead to underestimation of risk, and a more balanced approach should be considered in risk assessment.
- Published
- 2019
- Full Text
- View/download PDF
26. Effect of High-Voltage Additives on Formation of Solid Electrolyte Interphases in Lithium-Ion Batteries
- Author
-
Minjing Chen, Yunbo Huang, Zhepu Shi, Hao Luo, Zhaoping Liu, and Cai Shen
- Subjects
solid electrolyte interphase ,high-voltage electrolyte ,additives ,electrochemical atomic force microscopy ,lithium-ion batteries ,Technology ,Electrical engineering. Electronics. Nuclear engineering ,TK1-9971 ,Engineering (General). Civil engineering (General) ,TA1-2040 ,Microscopy ,QH201-278.5 ,Descriptive and experimental mechanics ,QC120-168.85 - Abstract
Solid electrolyte interphase (SEI) formed at the interface in lithium-ion batteries plays an important role in isolating electrons and permeating ions during charging/discharging processes. Therefore, the formation of a good interface is crucial for better battery performance. In this study, additives based on adiponitrile (ADN) and trimethyl borate (TMB) were employed to broaden the electrochemical window and form a good SEI layer. Electrochemical Atomic force microscopy (EC-AFM) was used for in situ studies of film-formation mechanisms in high-voltage electrolytes on high-temperature pyrolytic graphite (HOPG), as well as Li- and Mn-rich (LMR) materials. X-ray photoelectron spectroscopy (XPS) combined with electrochemical methods revealed a synergistic reaction between the two additives to form a more stable interfacial film during charging/discharging processes to yield assembled batteries with improved cycle performance, its capacity increased from below 100 mAh/g to 200 mAh/g after 50 cycles. In sum, these findings would have great significance for the development of high voltage lithium-ion batteries with enhanced performance.
- Published
- 2022
- Full Text
- View/download PDF
27. Coronary Angiography-Derived Diastolic Pressure Ratio
- Author
-
Yanjun Gong, Yundi Feng, Tieci Yi, Fan Yang, Yuxi Li, Long Zhang, Bo Zheng, Tao Hong, Zhaoping Liu, Yunlong Huo, Jianping Li, and Yong Huo
- Subjects
IFR ,DPR ,FFR ,CFD ,hemodynamics ,Biotechnology ,TP248.13-248.65 - Abstract
AimsBased on the aortic pressure waveform, a specially designed computational fluid dynamic (CFD) method was proposed to determine coronary angiography-derived diastolic pressure ratio (caDPR) without using invasive pressure wire. The aim of the study is to retrospectively assess diagnostic performance of the caDPR in the catheterization laboratory, based on a previous multicenter trial for online assessment of coronary angiography-derived FFR (caFFR).Methods and ResultsPatients with diagnosis of stable or unstable angina pectoris were enrolled in six centers. Wire-derived FFR was measured in coronary arteries with 30–90% diameter stenosis. Offline caDPR was assessed in blinded fashion against wire-derived FFR at an independent core laboratory. A total of 330 patients who met the inclusion/exclusion criteria were enrolled from June 26 to December 18, 2018. Offline computed caDPR and wire-derived FFR were compared in 328 interrogated vessels. The caDPR with a cutoff value of 0.89 shows diagnostic accuracy of 87.7%, sensitivity of 89.5%, specificity of 86.8%, and AUC of 0.940 against the wire-derived FFR with a cutoff value of 0.80.ConclusionsUsing wired-based FFR as the standard reference, there is good diagnostic performance of the novel-CFD-design caDPR. Hence, caDPR could enhance the hemodynamic assessment of coronary lesions.
- Published
- 2020
- Full Text
- View/download PDF
28. Estimating the national burden of mild intellectual disability in children exposed to dietary lead in China
- Author
-
Yizhong Yan, Sulian Yang, Yujing Zhou, Yan Song, Jiao Huang, Zhaoping Liu, Yibaina Wang, and Sheng Wei
- Subjects
Environmental sciences ,GE1-350 - Abstract
The effects of lead as a dietary pollutant remain a global public health concern that needs urgent resolution. Children are highly susceptible to the adverse outcomes of lead pollution, as even low levels of lead may cause irreversible damage to intellectual development. Since several sources of lead exposure are present in the environment, it is necessary to identify the attributable burden of lead-related diseases arising from different exposure sources. In the present study, we used epidemiological data from studies around the nation to estimate the burden of mild intellectual disability (MID) attributed to lead exposure sources by using disability-adjusted life years (DALYs). To this end, a dose-response approach was used and a model comprising three components was established: exposure, dose-response, and DALYs module. In Chinese children aged 0–6 years, blood lead levels (BLLs) of 5.34 ± 3.09 μg/dL resulted in a MID incidence rate of 12.84 cases per 1000 children, with an estimated burden of disease (BoD) of 42.23 DALYs per 1000 children. Owing to dietary lead exposure, 36.64 healthy life years per 1000 children were lost, which was notably higher than the outcomes associated with exposure from other sources. This was consistent with the result that dietary exposure was the main contributor to children’s lead exposure, accounting for 86.76%. According to the regional distribution based on the existing literature, the areas in China with higher BLLs were Heilongjiang, Shanxi, and Jiangxi. Our findings provided the information for lead risk management decisions and policies making. Keywords: Lead, Children, Diet, MID, BoD
- Published
- 2020
- Full Text
- View/download PDF
29. Metastability and Reversibility of Anionic Redox-Based Cathode for High-Energy Rechargeable Batteries
- Author
-
Bao Qiu, Minghao Zhang, Seung-Yong Lee, Haodong Liu, Thomas A. Wynn, Lijun Wu, Yimei Zhu, Wen Wen, Craig M. Brown, Dong Zhou, Zhaoping Liu, and Ying Shirley Meng
- Subjects
structural metastability ,structural reversibility ,anionic redox ,voltage recovery ,cathode materials ,high energy li-ion battery ,Physics ,QC1-999 - Abstract
Summary: Great focus has recently been placed on anionic redox, to which high capacities of Li-rich layered oxides are attributed. With almost doubled capacity compared with state-of-the-art cathode materials, Li-rich layered oxides still fall short in other performance metrics. Among these, voltage decay upon cycling remains the most hindering obstacle, in which defect electrochemistry plays a critical role. Here, we reveal that the metastable state of cycled Li-rich layered oxide, which stems from structural defects in different dimensions, is responsible for the voltage decay. More importantly, through mild thermal energy, the metastable state can be driven to a stable state, bringing about structural and voltage recovery. However, for the classic layered oxide without reversible anionic redox, thermal energy can only introduce cation disordering, leading to performance deterioration. These insights elucidate that understanding the structure metastability and reversibility is essential for implementing design strategies to improve cycling stability for high-capacity layered oxides.
- Published
- 2020
- Full Text
- View/download PDF
30. Estimated assessment of cumulative dietary exposure to organophosphorus residues from tea infusion in China
- Author
-
Pei Cao, Dajin Yang, Jianghui Zhu, Zhaoping Liu, Dingguo Jiang, and Haibin Xu
- Subjects
Organophosphorus residues ,Cumulative dietary exposure ,Risk assessment ,Tea infusion ,Public aspects of medicine ,RA1-1270 - Abstract
Abstract Background China has the world’s largest tea plantation area in the world. To sustain high yields of the tea, multiple pesticides are used on tea crops to control pests. Organophosphorus (OP) pesticides are among the most widely used types of agricultural pesticides in China. As tea is a significant potential source of exposure to pesticide residues, the public concern has increased in relation to pesticide residues found in tea in China. The aim of the study was to estimate cumulative dietary exposure to OP residues from tea infusion for Chinese tea consumers to determine whether exposure to OP residues from tea infusion is a cause of health concern for tea consumers in China. Methods OP residue data were obtained from the China National Monitoring Program on Food Safety (2013–2014), encompassing 1687 tea samples from 12 provinces. Tea consumption data were obtained from the China National Nutrient and Health Survey (2002), comprising 506 tea consumers aged 15–82 years. The transfer rates of residues from tea leaves into tea infusions were obtained from the literature. The relative potency factor (RPF) approach was used to estimate acute cumulative exposure to 20 OP residues from tea infusion using methamidophos as the index compound. Dietary exposure was calculated in a probabilistic way. Results For tea consumers, the mean and the 99.9th percentile (P99.9) of cumulative dietary exposure to OP residues from tea infusion equalled 0.08 and 1.08 μg/kg bw/d. When compared with the acute reference dose (ARfD), 10 μg/kg bw/d for methamidophos, this accounts for 0.8 and 10.8% of the ARfD. Conclusions Even when considering OP residues from vegetables, fruits and other foods, there are no health concerns based on acute dietary exposure to OP residues from tea infusion. However, it is necessary to strengthen the management of the OP pesticides used on tea in China to reduce the risk of chronic dietary exposure to OPs from tea infusion.
- Published
- 2018
- Full Text
- View/download PDF
31. Fluorinated Electrolytes for Li-Ion Batteries: The Lithium Difluoro(oxalato)borate Additive for Stabilizing the Solid Electrolyte Interphase
- Author
-
Lan Xia, Saixi Lee, Yabei Jiang, Yonggao Xia, George Z. Chen, and Zhaoping Liu
- Subjects
Chemistry ,QD1-999 - Published
- 2017
- Full Text
- View/download PDF
32. Cu-Doped-ZnO Nanocrystals Induce Hepatocyte Autophagy by Oxidative Stress Pathway
- Author
-
Qianyu Bai, Yeru Wang, Luoyan Duan, Xiaomu Xu, Yusheng Hu, Yue Yang, Lei Zhang, Zhaoping Liu, Huihui Bao, and Tianlong Liu
- Subjects
CZON ,biodistribution ,dose-dependent toxicity ,autophagy ,Chemistry ,QD1-999 - Abstract
As a novel nanomaterial for cancer therapy and antibacterial agent, Cu-doped-ZnO nanocrystals (CZON) has aroused concern recently, but the toxicity of CZON has received little attention. Results of hematology analysis and blood biochemical assay showed that a 50 mg/kg dosage induced the increase in white blood cells count and that the concentration of alanine aminotransferase (ALT), superoxide dismutase (SOD), catalase (CAT), and Malonaldehyde (MDA) in the serum, liver, and lungs of the CZON group varied significantly from the control mice. Histopathological examinations results showed inflammation and congestion in the liver and lung after a single injection of CZON at 50 mg/kg. A transmission electron microscope (TEM) result manifested the autolysosome of hepatocyte of mice which received CZON at 50 mg/kg. The significant increase in LC3-II and decrease in p62 of hepatocyte in vivo could be seen in Western blot. These results indicated that CZON had the ability to induce autophagy of hepatocyte. The further researches of mechanism of autophagy revealed that CZON could produce hydroxyl radicals measured by erythrocyte sedimentation rate (ESR). The result of bio-distribution of CZON in vivo, investigated by ICP-OES, indicated that CZON mainly accumulated in the liver and two spleen organs. These results suggested that CZON can induce dose-dependent toxicity and autophagy by inducing oxidative stress in major organs. In summary, we investigated the acute toxicity and biological distribution after the intravenous administration of CZON. The results of body weight, histomorphology, hematology, and blood biochemical tests showed that CZON had a dose-dependent effect on the health of mice after a single injection. These results indicated that CZON could induce oxidative damage of the liver and lung by producing hydroxyl radicals at the higher dose.
- Published
- 2021
- Full Text
- View/download PDF
33. Characterization of Li-rich layered oxides by using transmission electron microscope
- Author
-
Hu Zhao, Bao Qiu, Haocheng Guo, Kai Jia, Zhaoping Liu, and Yonggao Xia
- Subjects
Renewable energy sources ,TJ807-830 ,Ecology ,QH540-549.5 - Abstract
Lithium-rich layered oxides (LrLOs) deliver extremely high specific capacities and are considered to be promising candidates for electric vehicle and smart grid applications. However, the application of LrLOs needs further understanding of the structural complexity and dynamic evolution of monoclinic and rhombohedral phases, in order to overcome the issues including voltage decay, poor rate capability, initial irreversible capacity loss and etc. The development of aberration correction for the transmission electron microscope and concurrent progress in electron spectroscopy, have fueled rapid progress in the understanding of the mechanism of such issues. New techniques based on the transmission electron microscope are first surveyed, and the applications of these techniques for the study of the structure, migration of transition metal, and the activation of oxygen of LrLOs are then explored in detail, with a particular focus on the mechanism of voltage decay. Keywords: Lithium-ion battery, Transmission electron microscope, Lithium-rich layered oxide, Cathode material
- Published
- 2017
- Full Text
- View/download PDF
34. Gas–solid interfacial modification of oxygen activity in layered oxide cathodes for lithium-ion batteries
- Author
-
Bao Qiu, Minghao Zhang, Lijun Wu, Jun Wang, Yonggao Xia, Danna Qian, Haodong Liu, Sunny Hy, Yan Chen, Ke An, Yimei Zhu, Zhaoping Liu, and Ying Shirley Meng
- Subjects
Science - Abstract
Oxygen activity can play a vital role in determining charge transport properties of materials. Here, the authors demonstrate a method to create oxygen vacancies on layered oxides via a gas-solid interface reaction, leading to materials with enhanced energy and power densities for Li-ion batteries.
- Published
- 2016
- Full Text
- View/download PDF
35. Water-mediated cation intercalation of open-framework indium hexacyanoferrate with high voltage and fast kinetics
- Author
-
Liang Chen, Hezhu Shao, Xufeng Zhou, Guoqiang Liu, Jun Jiang, and Zhaoping Liu
- Subjects
Science - Abstract
Rechargeable aqueous metal-ion batteries are promising for large-scale applications, but performance and stability issues still remain. Here the authors utilize open-framework indium hexacyanoferrate cathodes to improve performance, showing that water-mediated cation intercalation occurs at the cathode.
- Published
- 2016
- Full Text
- View/download PDF
36. Large graphene-induced shift of surface-plasmon resonances of gold films: Effective-medium theory for atomically thin materials
- Author
-
Md Kamrul Alam, Chao Niu, Yanan Wang, Wei Wang, Yang Li, Chong Dai, Tian Tong, Xiaonan Shan, Earl Charlson, Steven Pei, Xiang-Tian Kong, Yandi Hu, Alexey Belyanin, Gila Stein, Zhaoping Liu, Jonathan Hu, Zhiming Wang, and Jiming Bao
- Subjects
Physics ,QC1-999 - Abstract
Despite successful modeling of graphene as a 0.34-nm-thick optical film synthesized by exfoliation or chemical vapor deposition (CVD), graphene-induced shift of surface-plasmon resonance (SPR) of gold films has remained controversial. Here we report the resolution of this controversy by developing a clean CVD graphene transfer method and extending Maxwell-Garnett effective-medium theory (EMT) to two-dimensional (2D) materials. A SPR shift of 0.24° is obtained and it agrees well with 2D EMT in which wrinkled graphene is treated as a 3-nm graphene/air layered composite, in agreement with the average roughness measured by atomic force microscopy. Because the anisotropic built-in boundary condition of 2D EMT is compatible with graphene's optical anisotropy, graphene can be modeled as a film thicker than 0.34 nm without changing its optical property; however, its actual roughness, i.e., effective thickness, will significantly alter its response to strong out-of-plane fields, leading to a larger SPR shift.
- Published
- 2020
- Full Text
- View/download PDF
37. Graphene/Sulfur/Carbon Nanocomposite for High Performance Lithium-Sulfur Batteries
- Author
-
Kangke Jin, Xufeng Zhou, and Zhaoping Liu
- Subjects
Li-S battery ,graphene ,β-cyclodextrin ,sulfur ,Chemistry ,QD1-999 - Abstract
Here, we report a two-step synthesis of graphene/sulfur/carbon ternary composite with a multilayer structure. In this composite, ultrathin S layers are uniformly deposited on graphene nanosheets and covered by a thin layer of amorphous carbon derived from β-cyclodextrin on the surface. Such a unique microstructure, not only improves the electrical conductivity of sulfur, but also effectively inhibits the dissolution of polysulfides during charging/discharging processes. As a result, this ternary nanocomposite exhibits excellent electrochemical performance. It can deliver a high initial discharge and charge capacity of 1410 mAh·g−1 and 1370 mAh·g−1, respectively, and a capacity retention of 63.8% can be achieved after 100 cycles at 0.1 C (1 C = 1675 mA·g−1). A relatively high specific capacity of 450 mAh·g−1 can still be retained after 200 cycles at a high rate of 2 C. The synthesis process introduced here is simple and broadly applicable to the modification of sulfur cathode for better electrochemical performance.
- Published
- 2015
- Full Text
- View/download PDF
38. Oxygen-defects evolution to stimulate continuous capacity increase in Co-free Li-rich layered oxides
- Author
-
Yibin Zhang, Xiaohui Wen, Zhepu Shi, Bao Qiu, Guoxin Chen, and Zhaoping Liu
- Subjects
Fuel Technology ,Electrochemistry ,Energy Engineering and Power Technology ,Energy (miscellaneous) - Published
- 2023
39. Tuning Local Structural Configurations to Improve Oxygen-Redox Reversibility of Li-Rich Layered Oxides
- Author
-
Yan Gong, Xiao Li, Lingcai Zeng, Yuanfei Huang, Bao Qiu, and Zhaoping Liu
- Subjects
General Materials Science ,Physical and Theoretical Chemistry - Published
- 2023
40. Complete revascularization based on angiography derived fractional flow reserve versus incomplete revascularization in patients with ST-segment elevation myocardial infarction.
- Author
-
Jiahui Liu, Kaiping Zhang, Xingang Wang, Zhaoping Liu, Ming Chen, Fangfang Fan, Jia Jia, Tao Hong, Jianping Li, Yong Huo, Yanjun Gong, and Bo Zheng
- Published
- 2024
- Full Text
- View/download PDF
41. Surface modification of carbon fiber cloth with graphene oxide through an electrophoresis method for lithium metal anode
- Author
-
Shengjie Xia, Qiang Guo, Yanan Yu, Yimei Li, Shuhui Wang, Daojie Dong, Zhenyuan Liu, Hongmin Zhou, Xufeng Zhou, and Zhaoping Liu
- Subjects
General Materials Science ,General Chemistry - Published
- 2023
42. Revealing Li-ion diffusion kinetic limitations in micron-sized Li-rich layered oxides
- Author
-
Yibin Zhang, Chong Yin, Bao Qiu, Guoxin Chen, You Shang, and Zhaoping Liu
- Subjects
Renewable Energy, Sustainability and the Environment ,Energy Engineering and Power Technology ,General Materials Science - Published
- 2022
43. Rational design of thermally stable polymorphic layered cathode materials for next generation lithium rechargeable batteries
- Author
-
Xiao Li, Qingwen Gu, Bao Qiu, Chong Yin, Zhining Wei, Wen Wen, Yibin Zhang, Yuhuan Zhou, Han Gao, Haoyan Liang, Zhilong He, Minghao Zhang, Ying Shirley Meng, and Zhaoping Liu
- Subjects
Mechanics of Materials ,Mechanical Engineering ,General Materials Science ,Condensed Matter Physics - Published
- 2022
44. Quantification of reversible and irreversible lithium in practical lithium-metal batteries
- Author
-
Wei Deng, Xue Yin, Wurigumula Bao, Xufeng Zhou, Zhiyuan Hu, Bangyi He, Bao Qiu, Ying Shirley Meng, and Zhaoping Liu
- Subjects
Fuel Technology ,Renewable Energy, Sustainability and the Environment ,Energy Engineering and Power Technology ,Electronic, Optical and Magnetic Materials - Published
- 2022
45. CNT/PVDF Composite Coating Layer on Cu with a Synergy of Uniform Current Distribution and Stress Releasing for Improving Reversible Li Plating/Stripping
- Author
-
Qiang Guo, Yanan Yu, Shengjie Xia, Cai Shen, Di Hu, Wei Deng, Daojie Dong, Xufeng Zhou, George Zheng Chen, and Zhaoping Liu
- Subjects
General Materials Science - Abstract
The uncontrollable formation of polymorphous Li deposits, e.g., whiskers, mosses, or dendrites resulting from nonuniform interfacial current distribution and internal stress release in the upward direction on the conventional current collector (e.g., Cu foil) of Li metal rechargeable batteries with a lithium-metal-free negatrode (LMFRBs), leads to rapid performance degradation or serious safety problems. The 3D carbon nanotubes (CNTs) skeleton has been proven to effectively reduce the current density and eliminate the internal accumulated stress. However, remarkable electrolyte decomposition, inherent Li source consumption due to repeated SEI formation, and Li
- Published
- 2022
46. Frequency-Reconfigurable Microstrip Patch Antenna Based on Graphene Film
- Author
-
Xinhai Wang, Liqiong Wu, Hua Chen, Wei Wang, and Zhaoping Liu
- Subjects
Computer Networks and Communications ,Hardware and Architecture ,Control and Systems Engineering ,Signal Processing ,Electrical and Electronic Engineering ,frequency-reconfigurable antenna ,graphene ,tunable conductivity ,voltage control - Abstract
Fifth-generation mobile communication systems must connect to multiple wireless networks. In order to enable a single device to match the frequency bands of multiple wireless networks, it is usually necessary to use multiple single-band or multi-band antennas, which occupy a large amount of space inside a given device. Using frequency-reconfigurable antennas to replace multiple single-function antennas is an effective way to solve this problem. In this paper, we propose a frequency-reconfigurable microstrip patch antenna based on graphene film, which fills the slot of the radiating patch with graphene film. It was found that the surface current of the antenna can be changed by changing the conductivity of graphene through bias voltage, which allows the operating mode of the antenna to switch between a nearly slotted antenna and a nearly unslotted antenna to achieve frequency reconfigurability. By changing the bias voltage from 0 V to 9 V, the resonant frequency of the antenna can be switched from 29.6 GHz to 40 GHz, and the center frequency can by altered by 10.4 GHz, corresponding to the reflection coefficients of −26 dB and −20.8 dB, respectively. The antenna achieves good matching in both operating modes.
- Published
- 2023
- Full Text
- View/download PDF
47. Synergistic Effects of Ni2+ and Mn3+ on the Electrochemical Activation of Li2MnO3 in Co-Free and Ni-Poor Li-Rich Layered Cathodes
- Author
-
Xiaohui Wen, Bao Qiu, Han Gao, Xiao Li, Zhepu Shi, and Zhaoping Liu
- Subjects
Materials Chemistry ,Electrochemistry ,Energy Engineering and Power Technology ,Chemical Engineering (miscellaneous) ,Electrical and Electronic Engineering - Published
- 2022
48. Trends in percutaneous coronary intervention in China: analysis of China PCI Registry Data from 2010 to 2018
- Author
-
Zhaoping Liu, Jianping Li, Yan Zhang, Bo Yu, Yitong Ma, Genshan Ma, Jianan Wang, Bin Liu, Xi Su, Bao Li, Zheng Zhang, Yuguo Chen, Jiyan Chen, Lianglong Chen, Yundai Chen, Zuyi Yuan, Shaobin Jia, Chuanyu Gao, Yida Tang, Xianghua Fu, Yaling Han, Junbo Ge, Xudong Ma, and Yong Huo
- Subjects
General Earth and Planetary Sciences - Published
- 2022
49. Highly Deformable Graphene/Poly(3,4-ethylenedioxythiophene):Poly(styrene Sulfonate) Hydrogel Composite Film for Stretchable Supercapacitors
- Author
-
Wen Chen, Han Xiao, Xufeng Zhou, Xueyan Xu, Shunqiong Jiang, Zhihong Qin, Shiyun Ding, Cancan Bian, and Zhaoping Liu
- Subjects
Materials Chemistry ,Electrochemistry ,Energy Engineering and Power Technology ,Chemical Engineering (miscellaneous) ,Electrical and Electronic Engineering - Published
- 2022
50. AmV2O5 with Binary Phases as High-Performance Cathode Materials for Zinc-Ion Batteries: Effect of the Pre-Intercalated Cations A and Reversible Transformation of Coordination Polyhedra
- Author
-
Shutao Zhang, Liang Chen, Daojie Dong, Yulin Kong, Jun Zhang, Junru Liu, and Zhaoping Liu
- Subjects
General Materials Science - Published
- 2022
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.