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Anomalous hysteresis loops measured by longitudinal and polar magneto-optical Kerr effects (MOKE) were observed in a Co/NiO/Cu/Co/Cu structure. After excluding other possible mechanisms, we explain the anomalous hysteresis loops in terms of the opposite rotation angles for the top- and bottom-Co layers. Ultimately, the opposite rotation angles are likely caused by the different incidence angles for the top- and bottom-Co layers. [ABSTRACT FROM AUTHOR]

The influence of a nano-nitride-layer (NNL) doped at different interfaces in the structure of Cu/Co/Cu/Co/Cu on magnetoresistance (MR) is investigated. As the NNL is doped at the inner interfaces of the core Co/Cu/Co sandwich, an inverse MR is observed. This contrasts sharply with that doping at the two outer interfaces between the core sandwich (Co/Cu/Co) and the buffer or/and the capping layers. The result arises from the negative spin asymmetry induced by the NNL doping under different interfacial circumstances. Moreover, the MR value increases in magnitude as temperature is decreased from room temperature to 4.2 K. [ABSTRACT FROM AUTHOR]

The understanding of the effect of vegetation on the flow and sediment transport is extremely important for modern river management and water ecological restoration. In this study, the laboratory experiments are carried out to study the 3D flow velocity, turbulence and sediment transport affected by 3 types of flexible vegetation. The results show that the submerged and emergent vegetation generates an obvious flow resistance and significantly alters the vertical distributions of the flow velocity, especially in the vegetated and downstream regions. Due to the influence of vegetation, the flow in downstream generates many vortices with different sizes. Compared with the submerged vegetation, the emergent vegetation has a more obvious influence on the vortex flow. Vegetation also results in a nearly constant fine suspended sediment concentration in the water column for all cases, while the large flow resistance has a stronger filtration effect on the coarse sediment, which leads the coarse sediment to be deposited and the total sediment along the vegetated channel to be gradually refined. The experiment also analyzes the influence of the transverse flow on the suspended sediment transport and the interaction mechanism of flow and sediment. [ABSTRACT FROM AUTHOR]

The effect of interfacial planar doping with an insulating granular layer in a sandwiched structure was studied. By inserting a thin SiO[sub 2]-Ni layer at either the Co/Cu (top) or Cu/Co (bottom) interface in sandwiched Co/Cu/Co structures, the magnetoresistance curve as a function of the magnetic field changed significantly. This change was due to a reduction of interlayer coupling and to a change in the switching mechanism of the magnetizations caused by modification of the interface. In addition, the dusted Co/Cu/Co structures showed flat peaks and small switching fields that would be very useful for practical applications. [ABSTRACT FROM AUTHOR]

Objective: Precise renal puncture is an essential but challenging step for successful percutaneous nephrolithotomy. We evaluated the efficiency of a novel real-time navigation system using Mixed Reality(MR) technology for human phantom kidney puncture. Methods: One human kidney phantom underwent MR-assisted percutaneous collecting system puncture. Two punctures were performed by each of 6 surgeons in the randomize selected upper, middle or lower calyces. Outcome measurements were the number of attempts for renal puncture, the time needed to evaluate the trajectory and to perform percutaneous puncture. Results: A total of 12 punctures were performed successfully using MR-Assisted Guidance. Median evaluation time and renal puncture time for the selected calyces was 13 (range 11 to 19) and 19 seconds (range 15 to 44), respectively. One or Two attempts were needed to achieve a successful renal puncture for all of the surgeons. Conclusions: The proposed MR-assisted guidance solution for renal collecting system puncture proved to be accurate, simple and quick. The inherent limitations of traditional X - ray and ultrasonic technology can be overcome.

Objective: To investigate the effects on human peripheral blood erythrocytes of long-term occupational contact with chromate. Methods: A dynamic cohort study was conducted of chromate-exposed workers (343 cases) and non-chromate-exposed workers (73 cases) at a chromate production enterprise who were selected according to specific inclusion and exclusion criteria from 2010 to 2015. Personal information and chromate exposure information were obtained by questionnaire. A generalized estimating equation was employed to analyze the effects on human peripheral blood erythrocytes of long-term occupational contact with chromate, controlling for age, gender, smoking, alcohol consumption and body mass index. Results: The mean ages and working ages of those entering the cohort study were 36.67 ±6.78 and 38.47 ± 7.18, respectively, for the exposure group and 8.39 ± 6.02 and 12.86 ± 8.34, respectively, for the control group. The erythrocyte content [(4.73±0.46), (4.81±0.53), (4.41±0.45)]×10 12 /L in the peripheral blood in the chromate exposure group was lower than that [(4.76±0.42), (4.95±0.45), (4.47±0.39)]×10 12 /L in the control group for the years 2010, 2011, 2012 and 2014 ( t values were 0.38, 1.96, 0.92 and 1.21; P values were 0.703, 0.051, 0.358 and 0.227, respectively). The correlations between the years 2010 and 2011, 2011 and 2012, 2012 and 2014, and 2014 and 2015 were 0.667, 0.464,-0.070 and 0.020, respectively ( P <0.001). The RR for males and those that consumed alcohol were 0.661 (95% CI: 0.616-0.709) and 0.910 (95% CI: 0.811- 1.201), respectively. Compared with the control group, the risk of reduced erythrocyte levels in the peripheral blood was increased by 0.915 (95% CI: 0.852- 0.982) in the chromate-exposed group. Conclusions: The erythrocyte content of peripheral blood was reduced after long-term exposure to chromate. Maleness and alcohol consumption were factors that increased the risk of reduced peripheral blood erythrocytes in the chromate-exposed population.

The goal of this study was to explore the polymorphisms of CYP2C19 (CYP2C19*2, CYP2C19*3) in patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI) on clopidogrel therapy in Zhengzhou city for guidance on clinical medication and reduction in the incidence of thromboembolic events. Two hundred and thirty-four ACS patients undergoing PCI were included in the study, including 171 males (average age = 64.13 ± 12 years) and 63 females (average age = 67.86 ± 10.20 years). Pyrosequencing analysis detected CYP2C19*2/*3 genotypes, which were divided into wild-type homozygous C/C, mutant heterozygous C/T, and mutant homozygous T/T. This study further explored the relationship between CYP2C19 polymorphisms and clopidogrel resistance in ACS patients. Gene frequencies of C/C, C/T, and T/T for CYP2C19*2 were 39.74, 50, and 10.26%, respectively, while the frequencies of C/C, C/T, and T/T for CYP2C19*3 were 94.02, 5.55, and 0.43%, respectively. According to platelet aggregation analysis, 203 cases normally responded to clopidogrel (86.8%) and 31 cases were clopidogrel resistant (13.2%). There was a correlation between gender and genotype distribution but none between age and genotype. In addition, patients with clopidogrel resistance were treated with ticagrelor antiplatelet therapy instead of clopidogrel, and only 1 case in all patients suffered thrombotic events during a 3-12 month follow-up. In conclusion, CYP2C19*2/*3 polymorphisms may be associated with clopidogrel resistance. Wild-type homozygote and single mutant heterozygote of CYP2C19*2/*3 can be given a normal dose of clopidogrel, while carriers with single mutant homozygote or double mutant heterozygote require ticagrelor antiplatelet therapy as an alternative.

In the present paper is stated the accomplishment of the studies of 17 populations of cultivated Fagopyrum tataricum (L.) Gaertn. from the counties of Yuexi and Ganluo in North Liangshan Autonomous Prefecture of Yi Nationality, Sichuan Province, China by means of starch gel electrophoresis and cluster analysis of agrobiology features. Seven enzymes, and 15 loci were assessed. The result shows that the genetic diversity of F. tataricum within population is higher than in the South Prefecture and in species F. esculentum from other areas. The A, P, Ho and He are 1.9, 52.1%, 0.190 and 0.262 respectively. The FST is 0.199 which is close to the average level of wild plants. A conservation strategy of the genetic resource of F. tataricum is suggested. Two populations of local variety "Youchiqiao" have the richest genetic diversity, P = 60.0%, Ho = 0.260 and 0.301 and they should be protected particularly. Two populations of local variety "Xiaomiqiao" with higher genetic diversity, as well as three populations of local varieties of "Qiukuqiao", "Equkuqiao" and "Geluokuqiao" with special genetic position should be protected too.

Genetic diversity and differentiation among 8 cultivated populations of Fagopyrum tataricum from the counties of Jinyang, Leibo and Miyi in south Liangshan Autonomous Prefecture of Yi Nationality, Sichuan Province, China were investigated using allozyme electrophoresis. The allozymic diversity is roughly correlated with agrobiological features. The results suggest that genetic diversity of F. tataricum is quite high. The mean number of alleles per locus A is 1.8; the percentage of polymorphic loci P is 46.6%, and the mean observed heterozygosities Ho and the mean expected heterozygosities He are 0.187 and 0.218 respectively, the ratios of gene diversities of heterozygosities Fsr is 0.22, which indicates that there is 22 percent of genetic differentiation among populations, and suggests that for protecting genetic resources all the populations should be included in.

The synthesis of a novel polyurethane block co-polymer containing a covalently attached, well-oriented RGD (Arg-Gly-Asp) peptide was explored. A poly(tetramethylene oxide) (PTMO)-based polyurethane was synthesized, and a bimolecular nucleophilic substitution reaction was then employed to incorporate ethyl carboxylate groups onto the polymer backbone (i.e. carboxylated polyurethane). Elemental analysis was used to determine the extent of carboxylation. The hexapeptide H-Gly-Arg-Gly-Asp-Ser-Tyr-OH was coupled to the carboxylated polyurethane via the formation of an amide bond. The attachment of the peptide was controlled by a protection-deprotection scheme. Nuclear magnetic resonance (NMR) and Fourier transform infrared (FTIR) spectroscopies were used to monitor the reactions. Sakaguchi assay and amino acid analysis confirmed that the RGD-containing peptide was successfully grafted onto the carboxylated polyurethane. This reaction scheme provides a new route for grafting end-linked, bioactive peptides onto polyurethanes.