Search

Your search keyword '"Zhao, Xue-Jie"' showing total 16 results
Start Over Author "Zhao, Xue-Jie"
16 results on '"Zhao, Xue-Jie"'

12. Evaluation of the Biological Activity of Folic Acid-Modified Paclitaxel-Loaded Gold Nanoparticles

Author

Ren,Bin, Cai,Zhong-Chao, Zhao,Xue-Jie, Li,Lin-Song, Zhao,Mei-Xia, Ren,Bin, Cai,Zhong-Chao, Zhao,Xue-Jie, Li,Lin-Song, and Zhao,Mei-Xia

Abstract

Bin Ren,1,2,* Zhong-Chao Cai,1,* Xue-Jie Zhao,1 Lin-Song Li,1 Mei-Xia Zhao1 1Key Laboratory of Natural Medicine and Immuno-Engineering of Henan Province, Henan University, Jinming Campus, Kaifeng, Henan, 475004, People’s Republic of China; 2School of Mathematics and Statistics, Henan University, Jinming Campus, Kaifeng, 475004, People’s Republic of China*These authors contributed equally to this workCorrespondence: Mei-Xia ZhaoKey Laboratory of Natural Medicine and Immune Engineering of Henan Province, Henan University, Jinming Campus, Kaifeng, Henan, 475004, People’s Republic of ChinaEmail zhaomeixia2011@henu.edu.cnPurpose: Gold nanoparticles (AuNPs) with good physical and biological properties are often used in medicine, diagnostics, food, and similar industries. This paper explored an AuNPs drug delivery system that had good target selectivity for folate-receptor overexpressing cells to induce apoptosis.Methods: A novel drug delivery system, Au@MPA-PEG-FA-PTX, was developed carrying paclitaxel (PTX) on folic acid (FA) and polyethylene glycol (PEG)-modified AuNPs. The nanomaterial was characterized by transmission electron microscopy (TEM), Fourier-transform infrared spectroscopy (FTIR), and ultraviolet-visible spectroscopy (UV-Vis). Also, the biological activity of the AuNPs drug delivery system was examined using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay in HL-7702, Hela, SMMC-7721, and HCT-116 cells. Furthermore, apoptotic activity using annexin V-FITC, mitochondrial membrane potential (MMP), and reactive oxygen species (ROS) levels was estimated by flow cytometry and fluorescence microscopy.Results: Au@MPA-PEG-FA-PTX exhibited a distinct core-shell structure with a controllable size of 28± 1 nm. Also, the AuNPs maintained good dispersion and spherical shape uniformity before and after modification. The MTT assay revealed good antitumor activity of the Au@MPA-PEG-FA-PTX against the Hela, SMMC-772

Published
2021

16. Organic cations directed 1D [Pb3Br10]4− chains: syntheses, crystal structures, and photoluminescence properties.

Author

Jing, Chang-Qing, Li, Jing-Zhao, Xu, Te, Jiang, Kuan, Zhao, Xue-Jie, Wu, Yu-Fang, Xue, Nian-Ting, Jing, Zhi-Hong, and Lei, Xiao-Wu

Subjects
CRYSTAL structure, METAL halides, QUANTUM efficiency, CRYSTAL lattices, EXCITON theory, PHOTOLUMINESCENCE, LUMINESCENCE
Abstract

Recently, low-dimensional organic–inorganic hybrid metal halides have attracted considerable attention in solid-state optical application fields, especially in white-light emitting diodes (WLEDs) owing to intrinsic broadband luminescence performances. Herein, by selecting different types of organic cations as a structural decoration strategy, we designed a series of new 1D hybrid halides of A2Pb3Br10 (A = NPM, DMPDA, TMEN) based on same [Pb3Br10]4− chains composed of edge-shared [Pb3Br12]6− trimers. The low-dimensional crystal lattice results in the formation of self-trapped excitons, which leads to broadband light emissions covering the entire visible region for all A2Pb3Br10 homologues. Specifically, compound 1 exhibits yellowish-white light emission (0.34, 0.45) with a photoluminescence quantum efficiency of 2.51%. Both compounds 2 and 3 show bluish-white light emissions centered at 438 nm and 440 nm, respectively, with high color rendering index (CRI) of 96, which belongs to one of the highest values to date. The intrinsic broadband white light emissions enable them as promising candidates for single-component white-light emitting materials. [ABSTRACT FROM AUTHOR]

Published
2021
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results