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The ultrasmall Ag species decorated on α‐Fe2O3 nanorods photocatalysts are prepared through a facile in situ photodeposition process. The obtained Ag/α‐Fe2O3 composite samples display more outstanding photocatalytic activity than original α‐Fe2O3 in the degradation of tetracycline hydrochloride (TC‐HCl) in water. The degradation rate constant of TC‐HCl over the Ag/α‐Fe2O3‐5 sample reaches up to 0.0118 min−1, which is about 6.21 times than that over original α‐Fe2O3 sample (0.0019 min−1). The structure characterizations, physicochemical properties, and photoelectrochemical measurements reveal that the visible light absorption ability and charge separation efficiency are improved dramatically owing to the decoration effect of ultrasmall Ag species on the surface of α‐Fe2O3 nanorods. The photocatalytic reaction mechanism investigations demonstrate that holes, ˙O2−, and ˙OH all are main active species and play important roles in the degradation process of TC‐HCl. [ABSTRACT FROM AUTHOR]

Background and Objectives: To characterize the clinical and neuroimaging phenotypes of patients with autoantibodies to γ-aminobutyric acid type A receptor (GABA A R)., Methods: Ten patients with autoantibodies against GABA A R from Huashan Hospital Autoimmune Encephalitis cohort were identified. We used MRI assessments and clinical examinations to summarize major clinical profile and visualize and quantify lesion distribution features. The relationship between clinical features, neuroimaging phenotypes, and topology of GABA A R expression were further investigated., Results: The median age at onset of 10 patients (8 male patients and 2 female patients) with anti-GABA A R encephalitis was 41.5 years (range: 17-73 years). All patients had prominent seizures and multifocal spotted or confluent lesions involved in limbic, frontal, and temporal lobes on brain MRI. Bilateral but asymmetric lesions in cingulate gyri were observed in all patients. These involved lesions could change dynamically with immunotherapies and relapse. Distribution of patients' brain MRI lesions was positively correlated with gene expression level of β3 subunit-containing GABA A R (Spearman ρ = 0.864, p = 0.001), the main target of autoantibodies. According to topology of lesions, patients with anti-GABA A R encephalitis could be classified into 2 clinical-radiological types: confluent type with bilateral confluent lesions involved in almost all limbic, frontal, and temporal lobes and spotted type with multiple scattered small-to-medium patchy lesions. Patients with confluent type exhibited worse clinical presentations and outcomes when compared with those with spotted type (maximum modified Rankin scale [mRS]: 5 [5-5] vs 3.5 [3-4], respectively, p = 0.008; follow-up mRS: 4 [2-6] vs 0.5 [0-1], respectively, p = 0.016)., Discussion: Anti-GABA A R encephalitis has distinctive neuroimaging phenotype. Cingulate gyri were frequently involved in this disorder. The topology of lesions might be associated with the distribution of β3 subunit-containing GABA A R and reflected patients' disease severity and outcomes., (Copyright © 2022 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology.)