Search

Deep brain stimulation (DBS) has been widely used for Parkinson's disease, essential tremor, dystonia, drug - resistant epilepsy and other diseases. The operation procedure of this surgical method is complicated, and it also has certain complications in clinical application, including surgical complications such as intracranial hemorrhage and infection, hardware complications such as lead fracture and displacement, and stimulation complications such as paresthesia and muscle spasm, in which lead fracture and erosion and infection of the skin behind the ear are common and troublesome complications. In clinical practice, we found that lead fracture and erosion and infection of the skin were mainly located behind the ear. Since 2012, Beijing Tiantan Hospital, Capital Medical University had applied the retroauricular bone grinding groove technology in DBS, which significantly reduced the incidence of lead fracture and erosion and infection of the skin. Therefore, the retroauricular bone grinding groove technology can effectively solve the above problems. This paper mainly introduces the retroauricular bone grinding groove technology and the clinical application attention matters, providing references for colleagues.

C19H18N2O, orthorhombic, Pna21 (no. 33), a = 21.838(2) Å, b = 13.9663(11) Å, c = 4.9806(4) Å, V = 1519.1(2) Å3, Z = 4, R gt(F) = 0.0702, wR ref(F 2) = 0.1948, T = 293 K.

C22H14Cl2F4N2Pt, monoclinic, P21/n (no. 14), a = 16.858(9) Å, b = 14.876(8) Å, c = 17.125(9) Å, β = 98.552(6)°, V = 4247(4) Å3, Z = 8, Rgt(F) = 0.0337, wRref(F2) = 0.0778, T = 296 K.

C13H13ClN2O3PtS, monoclinic, C2/c (no. 15), a = 7.9405(8) Å, b = 18.0744(18) Å, c = 21.513(2) Å, β = 98.781(1)∘, Z = 8, V = 3051.3(5) Å3, Rgt(F) = 0.0535, wRref(F2) = 0.0233, T = 296 K.

Deep brain stimulation (DBS) is one of the most effective treatment methods for movement disorders, but there are still limitations in efficacy and adverse reactions, which may be due to the existing stimulation mode is too fixed to adjust according to the individual situation of patients. Adaptive deep brain stimulation (aDBS) based on the level of brain electrophysiological activity can adjust the stimulation mode with the change of clinical symptoms, which is more effective. The preliminary study of aDBS confirms its effectiveness. This article describes the electrophysiological signals involved in aDBS and its application progress in movement disorders.

Graphene loaded ferric oxide (G/Fe3O4) composites were prepared by chemical modification using graphene and nano-Fe3O4 as raw materials. The composites were characterized by transmission electron microscope, X-ray diffractometer and Fourier infrared spectrometer, and G/Fe3O4 composites were added to SN 5W-30 lubricating oil, and the dispersion stability and tribological properties of composites in lubricating oil were studied by plasma spectrometer and four ball friction tester. The results show that G/Fe3O4 composite materials generated by the co-modification of oleic acid and silane coupling KH570 are better dispersed on the graphene surface than with oleic acid modification alone; precipitation stability experiments show 10 days later,iron content in the lubricating oil is decreased by 48.3% without composite added,iron content is decreased by 39% with oleic acid modified composite added, and iron content is decreased by 31.1% with oleic acid and KH570 jointly modified composite; four-ball experiments show that G/Fe3O4 composites acting as lubricating oil additives have good tribological properties, the use of oleic acid and KH570 joint modification effect is better than the use of oleic acid modification, the maximum card-free bite load PB is increased by 6.5%, the diameter of the mocha is decreased by 4.4% and the coefficient of friction is decreased by 4.8%.

To suppress airwave interference, a time-domain coded electromagnetic exploration method is proposed with Pseudo-Random Binary Sequences (PRBS) code as the source signal. Based on the PRBS code and receiving voltages, which are recorded simultaneously, the impulse response of the earth can be obtained by the time-domain deconvolution signal recovery method, and the target information is effectively contained in the impulse response. The selection methods of clock frequency and code length were analyzed and field experiments were carried out, which demonstrated that the signal quality of the EM data could be improved by decreasing the clock frequency, or increasing the code length. The proposed method could greatly suppress the airwave interference and effectively identify underground anomalies.

In view of problem that traditional method for advanced detection of coal mine water inrush cannot improve detection depth and resolution simultaneously, a method taking microwave chaotic signal as radar detection source was proposed. The method takes 580 MHz chaotic signal generated by Colpitts circuit as detection source, then applies it to advanced detection of coal mine water inrush, so as to get resolution of 5.5 cm unrelated to detection range, which improves detection accuracy.

ObjectiveThis study was undertaken to determine whether the vertical parasagittal approach or the lateral peri-insular/peri-Sylvian approach to hemispheric surgery is the superior technique in achieving long-term seizure freedom.MethodsWe conducted a post hoc subgroup analysis of the HOPS (Hemispheric Surgery Outcome Prediction Scale) study, an international, multicenter, retrospective cohort study that identified predictors of seizure freedom through logistic regression modeling. Only patients undergoing vertical parasagittal, lateral peri-insular/peri-Sylvian, or lateral trans-Sylvian hemispherotomy were included in this post hoc analysis. Differences in seizure freedom rates were assessed using a time-to-event method and calculated using the Kaplan-Meier survival method.ResultsData for 672 participants across 23 centers were collected on the specific hemispherotomy approach. Of these, 72 (10.7%) underwent vertical parasagittal hemispherotomy and 600 (89.3%) underwent lateral peri-insular/peri-Sylvian or trans-Sylvian hemispherotomy. Seizure freedom was obtained in 62.4% (95% confidence interval [CI] = 53.5%-70.2%) of the entire cohort at 10-year follow-up. Seizure freedom was 88.8% (95% CI = 78.9%-94.3%) at 1-year follow-up and persisted at 85.5% (95% CI = 74.7%-92.0%) across 5- and 10-year follow-up in the vertical subgroup. In contrast, seizure freedom decreased from 89.2% (95% CI = 86.3%-91.5%) at 1-year to 72.1% (95% CI = 66.9%-76.7%) at 5-year to 57.2% (95% CI = 46.6%-66.4%) at 10-year follow-up for the lateral subgroup. Log-rank test found that vertical hemispherotomy was associated with durable seizure-free progression compared to the lateral approach (p = .01). Patients undergoing the lateral hemispherotomy technique had a shorter time-to-seizure recurrence (hazard ratio = 2.56, 95% CI = 1.08-6.04, p = .03) and increased seizure recurrence odds (odds ratio = 3.67, 95% CI = 1.05-12.86, p = .04) compared to those undergoing the vertical hemispherotomy technique.SignificanceThis pilot study demonstrated more durable seizure freedom of the vertical technique compared to lateral hemispherotomy techniques. Further studies, such as prospective expertise-based observational studies or a randomized clinical trial, are required to determine whether a vertical approach to hemispheric surgery provides superior long-term seizure outcomes.