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549 results on '"Zhang Chunqiu"'

7. Research on the platform of combined multi-functional bioreactor loading performance

Author

Tan Qinsong, Zhang Chunqiu, Gao Lilan, and Men Yutao

Subjects
Engineering (General). Civil engineering (General), TA1-2040
Abstract

Mechanical environment plays an important role in the growth of cells, tissues and organs, in the study of mechanobiology and tissue engineering, and loading bioreactor acts as the basic platform. We developed a combined multi-functional bioreactor based on linear motor, and studied on the loading performance of different modules and loading methods. In the rolling / sliding loading module, in the effective distance for 50mm case, the bioreactor frequency is 0.01Hz to 0.3Hz. Under tensile and compressive loading module, the minimum amplitude of the bioreactor can reached 0.01mm while the frequency can reach 10Hz. Under the impact test module, in the effective distance for 50mm case, acceleration a=54.16m/s2 can be realized. In the high acceleration cyclic loading module, acceleration 8Gcan be realized. The combined multi-functional bioreactor provides conditions for the study related mechanobiology and tissue engineering.

Published
2016
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9. Experimental research on degradation performance of magnesium alloy affected by mechanical environment

Author

Dong Limin, Song Xinxin, Ye Jinduo, Zhang Chunqiu, Liu Nian, and Chen Wei

Subjects
Biodegradable magnesium alloy, Mechanical environment, Experimental research, Engineering (General). Civil engineering (General), TA1-2040
Abstract

Objective To research the mechanical properties of magnesium alloy degradation affected by mechanical environment. Methods: After being divided into 4 groups randomly such as No.1, 2, 3 and 4,12 AZ31 magnesium alloy screws need suspending in the vessels containing 35ml simulated body fluid. No.1 was control group. Group 1 was under no load condition, experimental group 2, 3, and 4 were discontinuously applied fixed axial compression load of 30N, 60N, 90N respectively on time. The weight loss of magnesium alloy screws and the amount of gas generated were measured regularly. Results: From the cumulative amount of hydrogen production, group 1 and group 4 were relatively large, whereas group 2 and group 3 were relatively small. From the weight loss of magnesium alloy screws, group 3 > group 4 > group 2 > group 1. Conclusions: The general trend is the greater the load, the faster the degradation.

Published
2015
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15. Research on an Thermal Management System and Its Control Strategy for Electric Vehicles

Author

Shang, Xuanqing, Ma, Xu, Zhang, Chunqiu, Li, Yonggang, Xu, Zhenpeng, China Society of Automotive Engineers, Angrisani, Leopoldo, Series Editor, Arteaga, Marco, Series Editor, Panigrahi, Bijaya Ketan, Series Editor, Chakraborty, Samarjit, Series Editor, Chen, Jiming, Series Editor, Chen, Shanben, Series Editor, Chen, Tan Kay, Series Editor, Dillmann, Rüdiger, Series Editor, Duan, Haibin, Series Editor, Ferrari, Gianluigi, Series Editor, Ferre, Manuel, Series Editor, Hirche, Sandra, Series Editor, Jabbari, Faryar, Series Editor, Jia, Limin, Series Editor, Kacprzyk, Janusz, Series Editor, Khamis, Alaa, Series Editor, Kroeger, Torsten, Series Editor, Li, Yong, Series Editor, Liang, Qilian, Series Editor, Martín, Ferran, Series Editor, Ming, Tan Cher, Series Editor, Minker, Wolfgang, Series Editor, Misra, Pradeep, Series Editor, Möller, Sebastian, Series Editor, Mukhopadhyay, Subhas, Series Editor, Ning, Cun-Zheng, Series Editor, Nishida, Toyoaki, Series Editor, Pascucci, Federica, Series Editor, Qin, Yong, Series Editor, Seng, Gan Woon, Series Editor, Speidel, Joachim, Series Editor, Veiga, Germano, Series Editor, Wu, Haitao, Series Editor, and Zhang, Junjie James, Series Editor

Published
2022
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27. Analyst Integrity

Author

Gu, Zhaoyang, primary, Hao, Rubin, additional, Zhang, Chunqiu, additional, and Xue, Jing, additional

Published
2024
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49. Numerical simulation on mass transfer in the bone lacunar-canalicular system under different gravity fields.

Author

Wang, Hao, Wang, Jiaming, Lyu, Linwei, Wei, Shuping, and Zhang, Chunqiu

Subjects
REDUCED gravity environments, MASS transfer, GRAVITY, FINITE element method, COMPUTER simulation, EXTRACELLULAR fluid, FLUID flow
Abstract

The bone lacunar-canalicular system (LCS) is a unique complex 3D microscopic tubular network structure within the osteon that contains interstitial fluid flow to ensure the efficient transport of signaling molecules, nutrients, and wastes to guarantee the normal physiological activities of bone tissue. The mass transfer laws in the LCS under microgravity and hypergravity are still unclear. In this paper, a multi-scale 3D osteon model was established to mimic the cortical osteon, and a finite element method was used to numerically analyze the mass transfer in the LCS under hypergravity, normal gravity and microgravity and combined with high-intensity exercise conditions. It was shown that hypergravity promoted mass transfer in the LCS to the deep lacunae, and the number of particles in lacunae increased more significantly from normal gravity to hypergravity the further away from the Haversian canal. The microgravity environment inhibited particles transport in the LCS to deep lacunae. Under normal gravity and microgravity, the number of particles in lacunae increased greatly when doing high-intensity exercise compared to stationary standing. This paper presents the first simulation of mass transfer within the LCS with different gravity fields combined with high-intensity exercise using the finite element method. The research suggested that hypergravity can greatly promote mass transfer in the LCS to deep lacunae, and microgravity strongly inhibited this mass transfer; high-intensity exercise increased the mass transfer rate in the LCS. This study provided a new strategy to combat and treat microgravity-induced osteoporosis. [ABSTRACT FROM AUTHOR]

Published
2024
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