Search

Seven CoIIcoordination polymers, [Co(btx)3(H2O)2](ClO4)2·(btx)·2H2O (1), [Co(btx)3(H2O)2](BF4)2·(btx)·2H2O (2), [Co(btx)2(H2O)2](NO3)2·2H2O (3), [Co(btx)2Cl2] (4), [Co(btx)(BA)2(H2O)2]·2HBA (5), [Co(btx)(IPA)] (6) and [Co3(btx)3(BTA)2(H2O)2] (7) (btx = (1,4-bis(1,2,4-triazol-1-ylmethyl)benzene), HBA = benzoic acid, H2IPA = isophthalic acid, H3BTA = benzene-1,3,5-tricarboxylic acid), have been hydrothermally synthesized and characterized. 1and 2are isostructural and show a 1D Co–μ2-btx–Co chain structure, in which btx acts as both a bridging and terminal ligand. 3is also a 1D chain structure but different from 1and 2. The CoIIions are bridged by double μ2-btx to form Co2–btx2rings, which were further connected into 1D chains by sharing the CoIIions of the rings. 4exists as a 2D grid with (4,4) topology structure. When aromatic acid was introduced to the synthetic system, three other coordination polymers 5–7were obtained. In 5, the 1D chain is as that of 1, except that the terminal ligand was replaced by BA−. 6shows a two-fold parallel interpenetration framework featuring a 6-cuninodal net with (33,46,55,6) Schlafli topological symbol. 7is an interesting 3D framework, which contains a 2-nodal net motif with the unprecedented (36,42,56,6)(39,49,53)2topology structure. The influence of the varieties of the structures and magnetic properties are studied and discussed in detail. [ABSTRACT FROM AUTHOR]

A boy, aged 6 years, attended the hospital due to global developmental delay for 6 years and recurrent fever and convulsions for 5 years. The boy was found to have delayed mental and motor development at the age of 3 months and experienced recurrent fever and convulsions since the age of 1 year, with intermittent canker sores and purulent tonsillitis. During the fever period, blood tests showed elevated white blood cell count, C-reactive protein, and erythrocyte sedimentation rate, which returned to normal after the fever subsides. Electroencephalography showed epilepsy, and genetic testing showed compound heterozygous mutations in the GPAA1 gene. The boy was finally diagnosed with glycosylphosphatidylinositol biosynthesis deficiency 15 (GPIBD15) and periodic fever. The patient did not respond well to antiepileptic treatment, but showed successful fever control with glucocorticoid therapy. This article reports the first case of GPIBD15 caused by GPAA1 gene mutation in China and summarizes the genetic features, clinical features, diagnosis, and treatment of this disease, which provides a reference for the early diagnosis and treatment of GPIBD15.

Selective dephosphorylation is full of great challenges in the field of biomimetic catalysis. To mimic the active sites of protein phosphatase, Hf-OH-Hf motif-containing metal-organic frameworks (MOFs) were obtained and structurally characterized, which are assembled from [Hf 48 Ni 6 ] cubic nanocages and exhibit good stability in various solvents and acid/base solutions. Catalytic investigations suggest as-synthesized Hf-Ni and Hf-Ni-NH 2 display accurate type-selectivity (selectively catalyzed P-O rather than S-O or C-O bonds) and position-selectivity (selectively catalyzed phosphomonoesters over phosphodiesters) for the hydrolysis of phosphoesters. Reaction kinetic studies further revealed the high activity of the catalytic sites in these catalysts, and the unique catalytic selectivity and high activity are comparable to phosphatase. Additionally, these MOF catalysts possess good recursivity and hypotoxicity. Control experiments (including Hf- and Zr-based isomorphous MOFs) and theoretical calculations indicate that both triplet nickel and Hf 6 clusters play significant roles in the unique binding site and favorable binding energy. To our knowledge, this is the first example of selective dephosphorylation through MOF catalysts as mimic enzymes, which paves a potential way for the development of specific therapeutic MOFs., Competing Interests: The authors declare no competing financial interest., (© 2021 The Authors. Published by American Chemical Society.)

Reconstructing the spectrum rapidly and accurately is the key to the research on high-fidelity reproduction. A characteristic spectrum extracting and matching method for high-fidelity printing is proposed aiming at the problem of complex conversion between spectrum and ink combination caused by multi-color. The method filters and extracts feature bands of primary ink through derivative spectrum, and a characteristic spectrum multi-threshold coding method is proposed. Considering the problem of subarea judgment in hi-fi printing, an average derivative spectrum is taken as characteristic spectrum of each subarea and a spectrum matching method between target spectrum and average derivative spectrum of sub-spaces is proposed. The results show that the feature bands extracted can represent spectral characteristic of primary color significantly and the precision of color conversion model based on feature bands is higher than the model based on full bands. The spectrum matching method can achieve a high accuracy in sub-space judgments and greatly improve the efficiency of color convention. The spectrum extracting and matching method has the high practicability.