142 results on '"Zhang, Yuannyu"'
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2. Structural variation cooperates with permissive chromatin to control enhancer hijacking–mediated oncogenic transcription
3. Metabolon formation regulates branched-chain amino acid oxidation and homeostasis
4. Epo-IGF1R cross talk expands stress-specific progenitors in regenerative erythropoiesis and myeloproliferative neoplasm
5. T/myeloid mixed phenotype acute leukaemia harbouring TLX3::BCL11B with TLX3 activation.
6. Regulation of mitochondrial biogenesis in erythropoiesis by mTORC1-mediated protein translation
7. Silencing of LINE-1 retrotransposons is a selective dependency of myeloid leukemia
8. Convergence of oncogenic cooperation at single-cell and single-gene levels drives leukemic transformation
9. A unified model of human hemoglobin switching through single-cell genome editing
10. 3122 – CD44-MEDIATED METABOLIC REWIRING IS A TARGETABLE LIABILITY OF IDH-MUTANT LEUKEMIA
11. Electron transport inhibition increases cellular dependence on purine transport and salvage
12. Table S3 from Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation
13. Supplementary Figures and Legends from Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation
14. Data from Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation
15. Multiplexed capture of spatial configuration and temporal dynamics of locus-specific 3D chromatin by biotinylated dCas9
16. Interrogation of enhancer function by enhancer-targeting CRISPR epigenetic editing
17. Light-activated macromolecular phase separation modulates transcription by reconfiguring chromatin interactions
18. MAP: model-based analysis of proteomic data to detect proteins with significant abundance changes
19. Targeting Cell Adhesion Molecules in IDH Mutant Myeloid Malignances
20. Structural Variation Cooperates with Permissive Chromatin to Control Enhancer Hijacking-Mediated Oncogenic Transcription
21. Disabling Uncompetitive Inhibition of Oncogenic IDH Mutations Drives Acquired Resistance
22. The mitochondrial respiratory chain is essential for haematopoietic stem cell function
23. Epo-IGF1R crosstalk expands stress-specific progenitors in regenerative erythropoiesis and myeloproliferative neoplasm
24. 3089 – ELUCIDATING NEW MECHANISMS OF ACQUIRED RESISTANCE TO IDH INHIBITION BY SATURATION VARIANT SCREENING OF BASE-EDITED LEUKEMIA CELLS
25. Regulation of embryonic haematopoietic multipotency by EZH1
26. Elucidating Mechanisms of Acquired Resistance to IDH Inhibition By Saturation Variant Screening of Base-Edited Leukemia Cells
27. Lactate Dehydrogenase A Governs Cardiac Hypertrophic Growth in Response to Hemodynamic Stress
28. Discovering How Heme Controls Genome Function Through Heme-omics
29. Noncoding Variants Connect Enhancer Dysregulation with Nuclear Receptor Signaling in Hematopoietic Malignancies
30. Interrogation of Enhancer Function by Enhanced CRISPR Epigenetic Editing
31. Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation
32. Installation of a cancer promoting WNT/SIX1 signaling axis by the oncofusion protein MLL-AF9
33. GATA/Heme Multi-Omics Reveals a Trace Metal-Dependent Erythrocyte Developmental Mechanism
34. GATA/Heme Multi-omics Reveals a Trace Metal-Dependent Cellular Differentiation Mechanism
35. CAPTURE:In SituAnalysis of Chromatin Composition of Endogenous Genomic Loci by Biotinylated dCas9
36. Dissecting super-enhancer hierarchy based on chromatin interactions
37. Installation of a Cancer Promoting WNT/SIX1 Signaling Axis by the Oncofusion Protein MLL-AF9
38. Temporal dynamics of cardiac hypertrophic growth in response to pressure overload
39. In Situ Capture of Chromatin Interactions by Biotinylated dCas9
40. Dissecting super-enhancer hierarchy based on chromatin interactions
41. Mitochondria Coordinate Intracellular Metabolism and Epigenetic Gene Regulation during Erythropoiesis
42. Dynamic Control of Enhancer Repertoires Drives Lineage and Stage-Specific Transcription during Hematopoiesis
43. Quantitative Proteomic and Transcriptomic Analysis Reveals Post-Transcriptional Regulation of Mitochondrial Biogenesis during Erythropoiesis
44. Targeting the Epigenetic and Metabolic Vulnerabilities of Ezh2-Deficiency-Induced Myeloid Neoplasms
45. Dissecting super-enhancer hierarchy based on chromatin interactions
46. CAPTURE: In SituAnalysis of Chromatin Composition of Endogenous Genomic Loci by Biotinylated dCas9
47. Regulation of embryonic haematopoietic multipotency by EZH1
48. Electron transport chain inhibition increases cellular dependence on purine transport and salvage.
49. Disabling Uncompetitive Inhibition of Oncogenic IDH Mutations Drives Acquired Resistance.
50. CAPTURE: In Situ Analysis of Chromatin Composition of Endogenous Genomic Loci by Biotinylated dCas9.
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