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Deep learning models in medical imaging face dual challenges: domain shift, where models perform poorly when deployed in settings different from their training environment, and class imbalance, where certain disease conditions are naturally underrepresented. We present Imbalance-Aware Domain Adaptation (IADA), a novel framework that simultaneously tackles both challenges through three key components: (1) adaptive feature learning with class-specific attention mechanisms, (2) balanced domain alignment with dynamic weighting, and (3) adaptive threshold optimization. Our theoretical analysis establishes convergence guarantees and complexity bounds. Through extensive experiments on embryo development assessment across four imaging modalities, IADA demonstrates significant improvements over existing methods, achieving up to 25.19\% higher accuracy while maintaining balanced performance across classes. In challenging scenarios with low-quality imaging systems, IADA shows robust generalization with AUC improvements of up to 12.56\%. These results demonstrate IADA's potential for developing reliable and equitable medical imaging systems for diverse clinical settings. The code is made public available at \url{https://github.com/yinghemedical/imbalance-aware_domain_adaptation}, Comment: 15 pages

Recent advances in Meta-learning for Black-Box Optimization (MetaBBO) have shown the potential of using neural networks to dynamically configure evolutionary algorithms (EAs), enhancing their performance and adaptability across various BBO instances. However, they are often tailored to a specific EA, which limits their generalizability and necessitates retraining or redesigns for different EAs and optimization problems. To address this limitation, we introduce ConfigX, a new paradigm of the MetaBBO framework that is capable of learning a universal configuration agent (model) for boosting diverse EAs. To achieve so, our ConfigX first leverages a novel modularization system that enables the flexible combination of various optimization sub-modules to generate diverse EAs during training. Additionally, we propose a Transformer-based neural network to meta-learn a universal configuration policy through multitask reinforcement learning across a designed joint optimization task space. Extensive experiments verify that, our ConfigX, after large-scale pre-training, achieves robust zero-shot generalization to unseen tasks and outperforms state-of-the-art baselines. Moreover, ConfigX exhibits strong lifelong learning capabilities, allowing efficient adaptation to new tasks through fine-tuning. Our proposed ConfigX represents a significant step toward an automatic, all-purpose configuration agent for EAs.

This paper proposes a novel approach for designing Single-Parameterized Kolmogorov-Arnold Networks (SKAN) by utilizing a Single-Parameterized Function (SFunc) constructed from trigonometric functions. Three new SKAN variants are developed: LSin-SKAN, LCos-SKAN, and LArctan-SKAN. Experimental validation on the MNIST dataset demonstrates that LArctan-SKAN excels in both accuracy and computational efficiency. Specifically, LArctan-SKAN significantly improves test set accuracy over existing models, outperforming all pure KAN variants compared, including FourierKAN, LSS-SKAN, and Spl-KAN. It also surpasses mixed MLP-based models such as MLP+rKAN and MLP+fKAN in accuracy. Furthermore, LArctan-SKAN exhibits remarkable computational efficiency, with a training speed increase of 535.01% and 49.55% compared to MLP+rKAN and MLP+fKAN, respectively. These results confirm the effectiveness and potential of SKANs constructed with trigonometric functions. The experiment code is available at https://github.com/chikkkit/LArctan-SKAN ., Comment: 7 pages, 3 figures, experiment code is available at https://github.com/chikkkit/LArctan-SKAN

The recently proposed Kolmogorov-Arnold Networks (KAN) networks have attracted increasing attention due to their advantage of high visualizability compared to MLP. In this paper, based on a series of small-scale experiments, we proposed the Efficient KAN Expansion Principle (EKE Principle): allocating parameters to expand network scale, rather than employing more complex basis functions, leads to more efficient performance improvements in KANs. Based on this principle, we proposed a superior KAN termed SKAN, where the basis function utilizes only a single learnable parameter. We then evaluated various single-parameterized functions for constructing SKANs, with LShifted Softplus-based SKANs (LSS-SKANs) demonstrating superior accuracy. Subsequently, extensive experiments were performed, comparing LSS-SKAN with other KAN variants on the MNIST dataset. In the final accuracy tests, LSS-SKAN exhibited superior performance on the MNIST dataset compared to all tested pure KAN variants. Regarding execution speed, LSS-SKAN outperformed all compared popular KAN variants. Our experimental codes are available at https://github.com/chikkkit/LSS-SKAN and SKAN's Python library (for quick construction of SKAN in python) codes are available at https://github.com/chikkkit/SKAN ., Comment: 25 pages, 14 figures, experiment codes are available at https://github.com/chikkkit/LSS-SKAN , and SKAN's Python library code are available at https://github.com/chikkkit/SKAN

Within the domain of medical analysis, extensive research has explored the potential of mutual learning between Masked Autoencoders(MAEs) and multimodal data. However, the impact of MAEs on intermodality remains a key challenge. We introduce MedFLIP, a Fast Language-Image Pre-training method for Medical analysis. We explore MAEs for zero-shot learning with crossed domains, which enhances the model's ability to learn from limited data, a common scenario in medical diagnostics. We verify that masking an image does not affect inter-modal learning. Furthermore, we propose the SVD loss to enhance the representation learning for characteristics of medical images, aiming to improve classification accuracy by leveraging the structural intricacies of such data. Our theory posits that masking encourages semantic preservation, robust feature extraction, regularization, domain adaptation, and invariance learning. Lastly, we validate using language will improve the zero-shot performance for the medical image analysis. MedFLIP's scaling of the masking process marks an advancement in the field, offering a pathway to rapid and precise medical image analysis without the traditional computational bottlenecks. Through experiments and validation, MedFLIP demonstrates efficient performance improvements, helps for future research and application in medical diagnostics.

Evolutionary algorithms, such as Differential Evolution, excel in solving real-parameter optimization challenges. However, the effectiveness of a single algorithm varies across different problem instances, necessitating considerable efforts in algorithm selection or configuration. This paper aims to address the limitation by leveraging the complementary strengths of a group of algorithms and dynamically scheduling them throughout the optimization progress for specific problems. We propose a deep reinforcement learning-based dynamic algorithm selection framework to accomplish this task. Our approach models the dynamic algorithm selection a Markov Decision Process, training an agent in a policy gradient manner to select the most suitable algorithm according to the features observed during the optimization process. To empower the agent with the necessary information, our framework incorporates a thoughtful design of landscape and algorithmic features. Meanwhile, we employ a sophisticated deep neural network model to infer the optimal action, ensuring informed algorithm selections. Additionally, an algorithm context restoration mechanism is embedded to facilitate smooth switching among different algorithms. These mechanisms together enable our framework to seamlessly select and switch algorithms in a dynamic online fashion. Notably, the proposed framework is simple and generic, offering potential improvements across a broad spectrum of evolutionary algorithms. As a proof-of-principle study, we apply this framework to a group of Differential Evolution algorithms. The experimental results showcase the remarkable effectiveness of the proposed framework, not only enhancing the overall optimization performance but also demonstrating favorable generalization ability across different problem classes., Comment: Accepted by IEEE Transactions on Systems, Man, and Cybernetics: Systems at Thu, Feb 29, 2024