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3. Understanding the Impact of Seasonal Climate Change on Canada's Economy by Region and Sector

Author

He, Shiyu, Bui, Trang, Huang, Yuying, Zhang, Wenling, Jian, Jie, Wong, Samuel W. K., and Wirjanto, Tony S.

Subjects
Statistics - Applications
Abstract

To assess the impact of climate change on the Canadian economy, we investigate and model the relationship between seasonal climate variables and economic growth across provinces and economic sectors. We further provide projections of climate change impacts up to the year 2050, taking into account the diverse climate change patterns and economic conditions across Canada. Our results indicate that rising Fall temperature anomalies have a notable adverse impact on Canadian economic growth. Province-wide, Saskatchewan and Manitoba are anticipated to experience the most substantial declines, whereas British Columbia and the Maritime provinces will be less impacted. Industry-wide, Mining is projected to see the greatest benefits, while Agriculture and Manufacturing are projected to have the most significant downturns. The disparities of climate change effects between provinces and industries highlight the need for governments to tailor their policies accordingly, and offer targeted assistance to regions and industries that are particularly vulnerable in the face of climate change. Targeted approaches to climate change mitigation are likely to be more effective than one-size-fits-all policies for the whole economy., Comment: 25 pages, 7 figures

Published
2023

31. Prognostic value and immunological role of MMRN1: a rising star in cancer.

Author

Zhou, Qing, Liu, Ying, Zhou, Jieyu, and Zhang, Wenling

Subjects
GENE expression profiling, CANCER prognosis, DRUG interactions, DRUG analysis, PROGNOSIS
Abstract

Background: Multimerin 1 (MMRN1) is a factor V binding protein, which can support platelet adhesion and thrombus formation. In recent years, the role of MMRN1 in cancer has begun to attract attention. But systematic studies in this area are lacking. Therefore, we used bioinformatics methods to analyze MMRN1 in tumors to reveal the possible role of MMRN1. Methods: Using the Cancer Genome Atlas (TCGA) and the Genotype-Tissue Expression (GTEx) database, we obtained relevant data for analyzing MMRN1. Using Gene Expression Profiling Interactive Analysis (GEPIA), Human Protein Atlas (HPA), TCGA, GeneMANIA, and cBioPortal, we explored the potential role of MMRN1 in different types of tumors. Tumor Immune System Interactions and Drug Bank (TISIDB) and Sangerbox were used to analyze the correlation between MMRN1 and tumor immunity. Gene set cancer analysis (GSCA) and UALCAN were used to analyze the methylation of MMRN1. GSCA was also used to analyze the drug sensitivity of MMRN1. Results: MMRN1 is down-regulated in most cancer types and is closely related to the prognosis of cancer patients. Interestingly, in most tumors, MMRN1 is positively correlated with immune -related genes. In addition, we observed different levels of methylation and mutations in different types of tumors. Drug sensitivity analysis found that MMRN1 was negatively correlated with several drugs, including GW-2580 and TL-1-85, suggesting that it can be used to develop potential anticancer therapies. Conclusion: Our analysis demonstrated a significant relationship between MMRN1 and prognosis, tumor immunity, and drug sensitivity of several tumors. As a rising star in cancer, it needs further research. [ABSTRACT FROM AUTHOR]

Published
2025
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34. Cancer

Author

Zhang, Wenling, Huang, Yumei, Xu, Jian, Pan, Shiyang, editor, and Tang, Jinhai, editor

Published
2021
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42. MsFcNET: Multi-scale Feature-Crossing Attention Network for Multi-field Sparse Data

Author

Xie, Zhifeng, Zhang, Wenling, Ding, Huiming, Ma, Lizhuang, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Woeginger, Gerhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Lauw, Hady W., editor, Wong, Raymond Chi-Wing, editor, Ntoulas, Alexandros, editor, Lim, Ee-Peng, editor, Ng, See-Kiong, editor, and Pan, Sinno Jialin, editor

Published
2020
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