Search

Your search keyword '"Zhang, Kang‐Da"' showing total 161 results
Start Over Author "Zhang, Kang‐Da"
161 results on '"Zhang, Kang‐Da"'

6. A light- and redox-switchable tristable [3]rotaxane with orthogonal controllable shuttling of different wheels.

Author

Gu, Xu-Hai, Yang, Jiang-Xiong, Liu, Li-Juan, Hai, Yu, Zhan, Tian-Guang, and Zhang, Kang-Da

Subjects
RELATIVE motion, WHEELS, PHOTOISOMERIZATION, DUMBBELLS, OXIDATION-reduction reaction
Abstract

While controlling the wheel shuttling of prototype [2]rotaxanes has been readily achieved, which promotes the development of intelligent supramolecular systems and materials, it remains a grand challenge to access higher ordered rotaxane systems with precisely controllable relative motion between component parts. Herein, a unique tristable [3]rotaxane was synthesized by threading two cyclobis(paraquat-p-phenylene) (CBPQT4+) macrocycles with a dumbbell component, which contained three recognition sites, including a photoactive azobenzene (AB) unit and a redox active tetrathiofulvalene (TTF) unit separated by a dioxynaphthalene (DNP) unit. Upon UV (365 nm)/yellow (> 525 nm) light irradiation, the Z/E photoisomerization of the AB unit could be triggered to drive the CBPQT4+ wheel (A) to shuttle between the AB and DNP units, with the CBPQT4+ wheel (B) maintained on the TTF unit. Furthermore, regulating the redox states of the TTF unit without light irradiation can induce the CBPQT4+ wheel (B) to shuttle between the TTF and DNP units. The construction of this unique orthogonal photo and redox stimuli-responsive [3]rotaxane is conducive to the development of higher ordered rotaxane-based molecular systems with controllable sophisticated properties and functions. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

13. Effect of Exercise Interventions on Health-Related Quality of Life in Patients with Fibromyalgia Syndrome: A Systematic Review and Network Meta-Analysis

Author

Zhang,Kang-Da, Wang,Lin-Yu, Zhang,Zhi-Hua, Zhang,Dan-Xu, Lin,Xiao-Wen, Meng,Tao, Qi,Feng, Zhang,Kang-Da, Wang,Lin-Yu, Zhang,Zhi-Hua, Zhang,Dan-Xu, Lin,Xiao-Wen, Meng,Tao, and Qi,Feng

Abstract

Kang-Da Zhang,1 Lin-Yu Wang,1 Zhi-Hua Zhang,1 Dan-Xu Zhang,1 Xiao-Wen Lin,2 Tao Meng,1 Feng Qi1 1Department of Anesthesiology, Qilu Hospital of Shandong University, Jinan, People’s Republic of China; 2Department of Pain Management, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, People’s Republic of ChinaCorrespondence: Tao Meng; Feng Qi, Department of Anesthesiology, Qilu Hospital of Shandong University, No.107 Wenhua Xilu, Jinan, Shandong, 250012, People’s Republic of China, Email mengtao@sdu.edu.cn; 198962001111@sdu.edu.cnObjective: Several guidelines highlight the beneficial impact of exercise on the management of symptoms and health-related quality of life (HRQOL) in patients with fibromyalgia syndrome (FMS). However, few analyses have compared different types of exercise. We, therefore, intent to compare the effects of different exercise types on improving the overall HRQOL and typical symptoms in patients with FMS.Methods: Medline, Embase, the Cochrane Register of Clinical Trials, and NIH ClinicalTrials.gov were searched from inception to April 21, 2022. Randomized clinical trials (RCTs) were included to assess the impact of exercise intervention on health parameters in adult FMS patients. Data were extracted independently and a frequentist network meta-analyses (NMA) was performed to rank the effects of interventions according to P-scores. The NMA evidence certainty was assessed using the method recommended by Grading of Recommendations Assessment, Development, and Evaluation Working Group.Results: A total of 57 RCTs were identified, including 3319 participants, involving 9 interventions (7 types of exercise, 2 controls). Of all treatments compared with usual care in efficacy outcomes, Mind-body exercise was associated with the best HRQOL (SMD, − 12.12; 95% CI, − 15.79 to − 8.45). On the other characteristic symptom dimensions, based on moderate quality evidence, sensorimotor training was associated with minim

Published
2022

16. Visible‐Light‐Switchable Tellurium‐Based Chalcogen Bonding: Photocontrolled Anion Binding and Anion Abstraction Catalysis.

Author

Duan, Hong‐Ying, Han, Shi‐Tao, Zhan, Tian‐Guang, Liu, Li‐Juan, and Zhang, Kang‐Da

Subjects
ANIONS, CATALYSIS, VISIBLE spectra, LIGAND binding (Biochemistry), AZOBENZENE
Abstract

Exploring new noncovalent bonding motifs with reversibly tunable binding affinity is of fundamental importance in manipulating the properties and functions of supramolecular self‐assembly systems and materials. Herein, for the first time, we demonstrate a unique visible‐light‐switchable telluro‐triazole/triazolium‐based chalcogen bonding (ChB) system in which the Te moieties are connected by azobenzene cores. The binding strengths between these azo‐derived ChB receptors and the halide anions (Cl−, Br−) could be reversibly regulated upon irradiation by visible light of different wavelengths. The cis‐bidentate ChB receptors exhibit enhanced halide anion binding ability compared to the trans‐monodentate receptors. In particular, the telluro‐triazolium‐based ChB receptor can achieve both high and significantly photoswitchable binding affinities for halide anions, which enable it to serve as an efficient photocontrolled organocatalyst for ChB‐assisted halide abstraction in a Friedel–Crafts alkylation benchmark reaction. [ABSTRACT FROM AUTHOR]

Published
2023
Full Text
View/download PDF

25. Photo‐Controlled Macroscopic Self‐Assembly Based on Photo‐Switchable Hetero‐Complementary Quadruple Hydrogen Bonds.

Author

Han, Shi‐Tao, Duan, Hong‐Ying, Chen, Lan‐Yun, Zhan, Tian‐Guang, Liu, Li‐Juan, Kong, Li‐Chun, and Zhang, Kang‐Da

Subjects
DIMERIZATION
Abstract

A photo‐switchable hetero‐complementary quadruple H‐bonding array, which consists of an azobenzene‐derived ureidopyrimidinone (UPy) module (Azo‐UPy) and a nonphotoactive diamidonaphthyridine (DAN) derivative (Napy‐1), is constructed based on a reversible photo‐locking approach. Upon UV (390 nm)/Vis (460 nm) light irradiations, photo‐switchable quadruple H‐bonded dimerization between Azo‐UPy and Napy‐1 can be achieved with exhibiting 4.8×104‐fold differences in binding strength (ON/OFF ratios). Furthermore, smart polymeric gels with unique photo‐controlled macroscopic self‐assembly behavior can be fabricated by introducing such quadruple H‐bonding array as photo‐regulable noncovalent interfacial connections. [ABSTRACT FROM AUTHOR]

Published
2021
Full Text
View/download PDF

35. The third orthogonal dynamic covalent bond

Author

Lascano, Santiago, Zhang, Kang-Da, Wehlauch, Robin, Gademann, Karl, Sakai, Naomi, Matile, Stefan, Lascano, Santiago, Zhang, Kang-Da, Wehlauch, Robin, Gademann, Karl, Sakai, Naomi, and Matile, Stefan

Abstract

Orthogonal dynamic covalent bonds are of interest for the construction of functional systems. The orthogonality of disulfide and hydrazone exchange under basic and acidic conditions, respectively, is well established. However, the integration of boronate esters as the third bond has failed so far because they exchanged too easily, especially under hydrazone exchange conditions. In this report, a collection of bioinspired catechols derived from adhesive natural products from cyanobacteria is screened with phenylboronic acids with proximal alcohols (benzoboroxoles), amines and fluorines to identify the least labile boronate esters. Moreover, Kool's 2-aminophenol catalysts are introduced to selectively accelerate hydrazone exchange without disturbing sufficiently inert boronate esters. Based on these results, we identified three different conditions to selectively exchange disulfides, hydrazones and boronate esters, that is to demonstrate the existence of three orthogonal dynamic covalent bonds. Moreover, their compatibility with functional systems is confirmed by successful hydrazone exchange in multicomponent surface architectures in the presence of intact boronate esters and disulfides.

Published
2016

Catalog

Books, media, physical & digital resources
See catalog results