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1,105 results on '"Zhang, Jingyan"'

1. HOI-M3:Capture Multiple Humans and Objects Interaction within Contextual Environment

Author

Zhang, Juze, Zhang, Jingyan, Song, Zining, Shi, Zhanhe, Zhao, Chengfeng, Shi, Ye, Yu, Jingyi, Xu, Lan, and Wang, Jingya

Subjects
Computer Science - Computer Vision and Pattern Recognition
Abstract

Humans naturally interact with both others and the surrounding multiple objects, engaging in various social activities. However, recent advances in modeling human-object interactions mostly focus on perceiving isolated individuals and objects, due to fundamental data scarcity. In this paper, we introduce HOI-M3, a novel large-scale dataset for modeling the interactions of Multiple huMans and Multiple objects. Notably, it provides accurate 3D tracking for both humans and objects from dense RGB and object-mounted IMU inputs, covering 199 sequences and 181M frames of diverse humans and objects under rich activities. With the unique HOI-M3 dataset, we introduce two novel data-driven tasks with companion strong baselines: monocular capture and unstructured generation of multiple human-object interactions. Extensive experiments demonstrate that our dataset is challenging and worthy of further research about multiple human-object interactions and behavior analysis. Our HOI-M3 dataset, corresponding codes, and pre-trained models will be disseminated to the community for future research., Comment: Accepted to CVPR 2024

Published
2024

3. Capturing the Unseen: Vision-Free Facial Motion Capture Using Inertial Measurement Units

Author

Wang, Youjia, Wu, Yiwen, Zhou, Hengan, Lin, Hongyang, Peng, Xingyue, Zhang, Jingyan, Zhu, Yingsheng, Jiang, Yingwenqi, Zhang, Yatu, Xu, Lan, Wang, Jingya, and Yu, Jingyi

Subjects
Computer Science - Computer Vision and Pattern Recognition
Abstract

We present Capturing the Unseen (CAPUS), a novel facial motion capture (MoCap) technique that operates without visual signals. CAPUS leverages miniaturized Inertial Measurement Units (IMUs) as a new sensing modality for facial motion capture. While IMUs have become essential in full-body MoCap for their portability and independence from environmental conditions, their application in facial MoCap remains underexplored. We address this by customizing micro-IMUs, small enough to be placed on the face, and strategically positioning them in alignment with key facial muscles to capture expression dynamics. CAPUS introduces the first facial IMU dataset, encompassing both IMU and visual signals from participants engaged in diverse activities such as multilingual speech, facial expressions, and emotionally intoned auditions. We train a Transformer Diffusion-based neural network to infer Blendshape parameters directly from IMU data. Our experimental results demonstrate that CAPUS reliably captures facial motion in conditions where visual-based methods struggle, including facial occlusions, rapid movements, and low-light environments. Additionally, by eliminating the need for visual inputs, CAPUS offers enhanced privacy protection, making it a robust solution for vision-free facial MoCap., Comment: Go to CAPUS project page https://sites.google.com/view/projectpage-capus and watch our video https://youtu.be/sR0GXxmBt8Y

Published
2024

5. Kinetics and mapping of Ca-driven calmodulin conformations on skeletal and cardiac muscle ryanodine receptors

Author

Rebbeck, Robyn T, Svensson, Bengt, Zhang, Jingyan, Samsó, Montserrat, Thomas, David D, Bers, Donald M, and Cornea, Razvan L

Subjects
Medical Physiology, Biomedical and Clinical Sciences, Cardiovascular, Heart Disease, Aetiology, 2.1 Biological and endogenous factors, Ryanodine Receptor Calcium Release Channel, Calmodulin, Calcium, Myocardium, Kinetics, Animals, Muscle, Skeletal, Fluorescence Resonance Energy Transfer, Humans, Protein Conformation, Protein Binding, Sarcoplasmic Reticulum
Abstract

Calmodulin transduces [Ca2+] information regulating the rhythmic Ca2+ cycling between the sarcoplasmic reticulum and cytoplasm during contraction and relaxation in cardiac and skeletal muscle. However, the structural dynamics by which calmodulin modulates the sarcoplasmic reticulum Ca2+ release channel, the ryanodine receptor, at physiologically relevant [Ca2+] is unknown. Using fluorescence lifetime FRET, we resolve different structural states of calmodulin and Ca2+-driven shifts in the conformation of calmodulin bound to ryanodine receptor. Skeletal and cardiac ryanodine receptor isoforms show different calmodulin-ryanodine receptor conformations, as well as binding and structural kinetics with 0.2-ms resolution, which reflect different functional roles of calmodulin. These FRET methods provide insight into the physiological calmodulin-ryanodine receptor structural states, revealing additional distinct structural states that complement cryo-EM models that are based on less physiological conditions. This technology will drive future studies on pathological calmodulin-ryanodine receptor interactions and dynamics with other important ryanodine receptor bound modulators.

Published
2024

12. Application of Temperature Prediction Method for DC Bus Film Capacitance in Electric Vehicles

Author

Zhang, Jingyan, Wu, Fangrong, Yu, Qian, Liu, Jin, Liu, Chenyi, Angrisani, Leopoldo, Series Editor, Arteaga, Marco, Series Editor, Chakraborty, Samarjit, Series Editor, Chen, Shanben, Series Editor, Chen, Tan Kay, Series Editor, Dillmann, Rüdiger, Series Editor, Duan, Haibin, Series Editor, Ferrari, Gianluigi, Series Editor, Ferre, Manuel, Series Editor, Jabbari, Faryar, Series Editor, Jia, Limin, Series Editor, Kacprzyk, Janusz, Series Editor, Khamis, Alaa, Series Editor, Kroeger, Torsten, Series Editor, Li, Yong, Series Editor, Liang, Qilian, Series Editor, Martín, Ferran, Series Editor, Ming, Tan Cher, Series Editor, Minker, Wolfgang, Series Editor, Misra, Pradeep, Series Editor, Mukhopadhyay, Subhas, Series Editor, Ning, Cun-Zheng, Series Editor, Nishida, Toyoaki, Series Editor, Oneto, Luca, Series Editor, Panigrahi, Bijaya Ketan, Series Editor, Pascucci, Federica, Series Editor, Qin, Yong, Series Editor, Seng, Gan Woon, Series Editor, Speidel, Joachim, Series Editor, Veiga, Germano, Series Editor, Wu, Haitao, Series Editor, Zamboni, Walter, Series Editor, Tan, Kay Chen, Series Editor, Wen, Fushuan, editor, and Aris, Ishak Bin, editor

Published
2024
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28. Cardiac ryanodine receptor N-terminal region biosensors identify novel inhibitors via FRET-based high-throughput screening

Author

Zhang, Jingyan, Singh, Daniel P, Ko, Christopher Y, Nikolaienko, Roman, Yuen, Siobhan M Wong King, Schwarz, Jacob A, Treinen, Levy M, Tung, Ching-Chieh, Rožman, Kaja, Svensson, Bengt, Aldrich, Courtney C, Zima, Aleksey V, Thomas, David D, Bers, Donald M, Launikonis, Bradley S, Van Petegem, Filip, and Cornea, Razvan L

Subjects
Medical Physiology, Biomedical and Clinical Sciences, Pediatric, Heart Disease, Cardiovascular, Biotechnology, Development of treatments and therapeutic interventions, 5.1 Pharmaceuticals, Animals, Biosensing Techniques, Calcium, Fluorescence Resonance Energy Transfer, High-Throughput Screening Assays, Mice, Muscle, Skeletal, Ryanodine Receptor Calcium Release Channel, FRET, N-terminal region, fluorescence lifetime, high-throughput screening, myopathy, ryanodine receptor, Chemical Sciences, Biological Sciences, Medical and Health Sciences, Biochemistry & Molecular Biology, Biological sciences, Biomedical and clinical sciences, Chemical sciences
Abstract

The N-terminal region (NTR) of ryanodine receptor (RyR) channels is critical for the regulation of Ca2+ release during excitation-contraction (EC) coupling in muscle. The NTR hosts numerous mutations linked to skeletal (RyR1) and cardiac (RyR2) myopathies, highlighting its potential as a therapeutic target. Here, we constructed two biosensors by labeling the mouse RyR2 NTR at domains A, B, and C with FRET pairs. Using fluorescence lifetime (FLT) detection of intramolecular FRET signal, we developed high-throughput screening (HTS) assays with these biosensors to identify small-molecule RyR modulators. We then screened a small validation library and identified several hits. Hits with saturable FRET dose-response profiles and previously unreported effects on RyR were further tested using [3H]ryanodine binding to isolated sarcoplasmic reticulum vesicles to determine effects on intact RyR opening in its natural membrane. We identified three novel inhibitors of both RyR1 and RyR2 and two RyR1-selective inhibitors effective at nanomolar Ca2+. Two of these hits activated RyR1 only at micromolar Ca2+, highlighting them as potential enhancers of excitation-contraction coupling. To determine whether such hits can inhibit RyR leak in muscle, we further focused on one, an FDA-approved natural antibiotic, fusidic acid (FA). In skinned skeletal myofibers and permeabilized cardiomyocytes, FA inhibited RyR leak with no detrimental effect on skeletal myofiber excitation-contraction coupling. However, in intact cardiomyocytes, FA induced arrhythmogenic Ca2+ transients, a cautionary observation for a compound with an otherwise solid safety record. These results indicate that HTS campaigns using the NTR biosensor can identify compounds with therapeutic potential.

Published
2022

29. Crosstalk of Phase-Leg Circuits with Parallel MOSFETs

Author

Li, Tongzhao, Dongye, Zhonghao, Mei, Weiyao, Zhang, Jingyan, Cai, Daomeng, Zhai, Guorui, Diao, Lijun, Angrisani, Leopoldo, Series Editor, Arteaga, Marco, Series Editor, Chakraborty, Samarjit, Series Editor, Chen, Jiming, Series Editor, Chen, Shanben, Series Editor, Chen, Tan Kay, Series Editor, Dillmann, Rüdiger, Series Editor, Duan, Haibin, Series Editor, Ferrari, Gianluigi, Series Editor, Ferre, Manuel, Series Editor, Jabbari, Faryar, Series Editor, Jia, Limin, Series Editor, Kacprzyk, Janusz, Series Editor, Khamis, Alaa, Series Editor, Kroeger, Torsten, Series Editor, Li, Yong, Series Editor, Liang, Qilian, Series Editor, Martín, Ferran, Series Editor, Ming, Tan Cher, Series Editor, Minker, Wolfgang, Series Editor, Misra, Pradeep, Series Editor, Mukhopadhyay, Subhas, Series Editor, Ning, Cun-Zheng, Series Editor, Nishida, Toyoaki, Series Editor, Oneto, Luca, Series Editor, Panigrahi, Bijaya Ketan, Series Editor, Pascucci, Federica, Series Editor, Qin, Yong, Series Editor, Seng, Gan Woon, Series Editor, Speidel, Joachim, Series Editor, Veiga, Germano, Series Editor, Wu, Haitao, Series Editor, Zamboni, Walter, Series Editor, Zhang, Junjie James, Series Editor, Tan, Kay Chen, Series Editor, Yang, Qingxin, editor, Dong, Xuzhu, editor, and Ma, Weiming, editor

Published
2023
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32. Magnetic proximity effect on the spin-valley coupling in two-dimensional Cr2Ge2Te6/2H-TMD van der Waals heterostructures.

Author

Zhao, Yanzhe, Huang, He, Zhang, Zeyu, Wang, Liming, Wu, Yanfei, Liu, Chuang, Zhang, Jingyan, Zheng, Xinqi, Zhou, Shiming, and Wang, Shouguo

Subjects
ANOMALOUS Hall effect, HETEROSTRUCTURES, PERPENDICULAR magnetic anisotropy, CIRCULAR polarization, POLAR effects (Chemistry), SILICON alloys, SEMIMETALS
Abstract

Two-dimensional (2D) transition metal dichalcogenides with 2H-phases, as a unique platform of valleytronics, display valley polarization and the well-known anomalous valley Hall effect when stacking with 2D magnetic substrates. In this study, we employ first-principles calculations to investigate the magnetic states, band structures, and magnetic proximity-dependent valley properties of 2D van der Waals heterostructures Cr2Ge2Te6/2H-MX2 (M = Mo, W, and X = S, Se, Te). Our findings reveal that the heterostructures possess stacking-dependent spontaneous valley polarization as well as pristine perpendicular magnetic anisotropy. Additionally, the Berry curvature and circular polarization demonstrate the presence of spin–momentum coupling characteristics, while the calculated non-zero Hall voltage indicates that the anomalous valley Hall effect can be achieved in valley-polarized systems. Furthermore, due to the strain effect and the electronic polarization at the interface, Cr2Ge2Te6/2H-MX2 heterostructures undergo the transition from semiconductors to semimetals upon substitution of early chalcogen elements. These calculations provide valuable insights for practical applications of valleytronics in 2D van der Waals heterostructure systems. [ABSTRACT FROM AUTHOR]

Published
2024
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34. Analysis of Non-local Multicontinuum Upscaling for Dual Continuum Model

Author

Zhang, Jingyan and Cheung, Siu Wun

Subjects
Mathematics - Numerical Analysis
Abstract

In this paper, we develop and analyze a rigorous multiscale upscaling method for dual continuum model, which serves as a powerful tool in subsurface formation applications. Our proposed method is capable of identifying different continua and capturing non-local transfer and effective properties in the computational domain via constructing localized multiscale basis functions. The construction of the basis functions consists of solving local problems defined on oversampling computational region, subject to the energy minimizing constraints that the mean values of the local solution are zero in all continua except for the one targeted. The basis functions constructed are shown to have good approximation properties. It is shown that the method has a coarse mesh dependent convergence. We present some numerical examples to illustrate the performance of the proposed method.

Published
2020

35. Polymerizable metal-organic frameworks for the preparation of mixed matrix membranes with enhanced interfacial compatibility

Author

Chen, Ziman, Yan, Dong, Ma, Liang, Zhang, Yahui, Zhang, Jingyan, Li, Hui, Khoo, Rebecca, Zhang, Jian, Svec, Frantisek, Lv, Yongqin, and Tan, Tianwei

Subjects
Inorganic Chemistry, Macromolecular and Materials Chemistry, Chemical Sciences, Engineering, Materials Engineering, Affordable and Clean Energy
Abstract

The preparation of flawless and defect-free mixed matrix membranes (MMMs) comprising metal-organic framework (MOF) and polymer is often difficult owing to the poor MOF/polymer interface compatibility. Herein, we present the synthesis of an important family of pillared-layered MOFs with polymerizable moieties based on the parent structure [Zn2L2P]n [L = vinyl containing benzenedicarboxylic acid linkers; P = 4,4'-bipyridine (bipy)]. The crystalline structures of polymerizable MOFs were analyzed using single-crystal X-ray crystallography. The presence of reactive double bonds in MOFs was verified by the successful thiol-ene click reaction with sulfhydryl compounds. The subsequent copolymerization of polymerizable MOFs with organic monomers produced mixed matrix membranes with enhanced MOF/polymer interfacial adhesion that enabled good separation efficiency of CO2 from flue gas. This strategy provides a stimulating platform to the preparation of highly efficient MMMs that are capable of mitigating energy consumption and environment issues.

Published
2021

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