Search

Your search keyword '"Zhang, Chenglu"' showing total 248 results
Start Over Author "Zhang, Chenglu"
248 results on '"Zhang, Chenglu"'

19. Synthesis and application of hypochlorite mediated acylhydrazone fluorescence probes.

Author

Zhang, Chenglu, Li, Xiangling, Wang, Yiming, Nie, Shiru, and Liu, Chang

Abstract

Hypochlorous acid (HClO/ClO−) is one of the important reactive oxygen species (ROS). It acts as a second signaling molecule within and between cells and is an indispensable active molecule in living organisms to regulate physiological and pathological processes. In this article, two fluorescent probes (PTF and PTA) for highly selective fluorescent recognition of ClO− were successfully synthesized based on the ICT mechanism by condensing phenothiazines with two hydrazides via the hydrazide structure (). PTF can identify different concentrations of ClO− in two steps. Due to its ClO− two site recognition, the probe exhibited good selectivity (specific recognition of ClO− over a wide concentration range), a fast time response (rapid recognition in seconds), a sufficiently low detection limit (3.6 and 11.0 nM), and large Stokes shifts (180 and 145 nm). Furthermore, the recognition of ClO− by contrasting probes with different substituents exhibited different fluorescence changes of ratiometric type and turn‐off. PTF successfully achieves the detection of exogenous and endogenous ClO− in aqueous solution and living cells. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

24. Sorption removal of cephalexin by HNO3 and H2O2 oxidized activated carbons

Author

Liu, WeiFeng, Xie, HuiJun, Zhang, Jian, and Zhang, ChengLu

Abstract

Abstract: Cephalexin’s traces within pharmaceutical effluents have toxic impact toward ecological and human health. Low-cost activated carbon derived from Trapa natans husk was oxidized with hydrogen peroxide and nitric acid, and tested for their ability to remove cephalexin from aqueous solutions. Oxidization with H2O2 showed negative effect on the cephalexin sorption, whereas HNO3 oxidization improved the adsorption. The cephalexin adsorption isotherms on the native and HNO3 oxidized carbons correlated well with the Freundlich equation while their kinetics followed the pseudo-second order model. The removal of cephalexin by the native and HNO3 oxidized carbons was found to be most favored at low ionic strength and strong acidic conditions. Based on the thermal and FTIR analyses, the interaction mechanisms of the interaction between cephalexin and the carbons were proposed. Electrostatic attraction, hydrophobic interaction and chemical bonding with surface functional groups were demonstrated as primary mechanisms for cephalexin removal. The nitrogen functionalities on the carbon surface were considered to be an important factor affecting the adsorption process.

Published
2024
Full Text
View/download PDF

48. A 3-position modified naphthalimide fluorescent probe for reversible response to H2O2and GSH and cell imaging

Author

Zhang, Chenglu, Nie, Shiru, Ding, Yanwei, Liu, Chang, Zhang, Yanpeng, Zhang, Yang, and Guo, Jinghao

Abstract

An “off–on–off” fluorescent probe NapEbfor high selectivity and reversible response to H2O2and GSH was synthesized. Inspired by the role of GSH in the human body, the –Se–N– bond in ebselen was successfully used as the recognition site. The probe NapEbis sensitive (LOD = 8.4 µM) and fast for H2O2(within 200 s). It can be used not only for qualitative and quantitative detection of H2O2in real samples, but also has been successfully used for the imaging detection of H2O2in MCF-7 cells with good effect. Moreover, continuous fluorescence recognition of GSH has also achieved significant results, the process is reversible and can be repeated for 5 times. The experimental results show that satisfactory results can also be obtained by structural modification at the 3-position of naphthalimide.

Published
2023
Full Text
View/download PDF

50. Surface patterning for combined digital image correlation and electron backscatter diffraction in-situ deformation experiments

Author

Zhang, Shiqi, Godfrey, Andrew William, Zhang, Chenglu, Liu, Wei, Juul Jensen, Dorte, Zhang, Shiqi, Godfrey, Andrew William, Zhang, Chenglu, Liu, Wei, and Juul Jensen, Dorte

Abstract

A considerable amount of information can be gained from combined collection of both digital image correlation (DIC) measurements, and of electron backscattered diffraction (EBSD) data from the same area during in-situ deformation experiments. Such data collection remains a challenge, however, due the influence of the surface markers required for DIC on the EBSD data quality. In this work we demonstrate that by careful control of the sample preparation process, a two-step electropolishing method can be used to generate excellent surface markers for DIC where the markers are integral features on the surface. The method does not require any special equipment and can be used to collect high quality EBSD data and DIC data with sub-micron resolution on the same area during repeated loading as part of in-situ deformation experiments. Combined EBSD and DIC measurements are illustrated in this work for samples of Al deformed in tension to a strain of 10%. Due to the integral nature of the surface markers we demonstrate also that it is possible to perform DIC measurements up to large plastic strains, including the necked region within a tensile sample. A comparison of EBSD and DIC data collected from the same area of a tensile-deformed sample shows that although the EBSD data provide excellent information on the lattice rotations developed during deformation, these data cannot be directly used as a measure of local plastic strain on the scale of the deformation microstructure. The ability to collect both EBSD and DIC data during an in-situ experiment provides, therefore, an opportunity to explore further the complex relationship between local plastic strain heterogeneity and EBSD-based measures of crystal lattice rotation.

Published
2020

Catalog

Books, media, physical & digital resources
See catalog results