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951 results on '"Zhai, Jin"'

5. Research progress of chronic low⁃grade inflammation and sleep disorders

Author

LIU Yin, TANG Yong⁃hong, ZHAI Jin⁃xia, and QIU Yuan

Subjects
sleep wake disorders, inflammation, immune system, review, Neurology. Diseases of the nervous system, RC346-429
Abstract

Sleep disorders can lead to persistent immune responses, activate related signal transduction pathways, and keep the body in a low⁃grade inflammatory state, which is a state of the level of proinflammatory factors is increased but does not cause invasive tissue damage or dysfunction. Long⁃term persistent chronic low ⁃ grade inflammation (CLGI) can promote the occurrence and development of sleep disorders. This article reviews the research progress of CLGI and sleep disorders, and explores new targets for the treatment of sleep disorders.

Published
2023
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9. Predicting tail events in a RIA-EVT-Copula framework

Author

Li, Wei-Zhen, Zhai, Jin-Rui, Jiang, Zhi-Qiang, Wang, Gang-Jin, and Zhou, Wei-Xing

Subjects
Quantitative Finance - Risk Management
Abstract

Predicting the occurrence of tail events is of great importance in financial risk management. By employing the method of peak-over-threshold (POT) to identify the financial extremes, we perform a recurrence interval analysis (RIA) on these extremes. We find that the waiting time between consecutive extremes (recurrence interval) follow a $q$-exponential distribution and the sizes of extremes above the thresholds (exceeding size) conform to a generalized Pareto distribution. We also find that there is a significant correlation between recurrence intervals and exceeding sizes. We thus model the joint distribution of recurrence intervals and exceeding sizes through connecting the two corresponding marginal distributions with the Frank and AMH copula functions, and apply this joint distribution to estimate the hazard probability to observe another extreme in $\Delta t$ time since the last extreme happened $t$ time ago. Furthermore, an extreme predicting model based on RIA-EVT-Copula is proposed by applying a decision-making algorithm on the hazard probability. Both in-sample and out-of-sample tests reveal that this new extreme forecasting framework has better performance in prediction comparing with the forecasting model based on the hazard probability only estimated from the distribution of recurrence intervals. Our results not only shed a new light on understanding the occurring pattern of extremes in financial markets, but also improve the accuracy to predict financial extremes for risk management., Comment: 14 pages, 5 figures, and 4 tables

Published
2020

27. Determination of Oleandrin in Blood and Liver Samples by LC-MS/MS

Author

ZHAI Jin-xiao, YAN Hui, SHEN Min，et al.

Subjects
forensic toxicology, poisoning, blood, liver, liquid chromatography-tandem mass spectrometry, oleandrin, Medicine
Abstract

Objective To develop a liquid chromatography-tandem mass spectrometry （LC-MS/MS） analytical method for the determination of oleandrin in blood and liver tissues, which could be applied to the cases of death caused by oleander poisoning. Methods Blood or liver tissues underwent a liquid-liquid extraction （LLE） using ethyl acetate, and the extract was separated on an Agilent ZORBAX SB-C18 column and eluted with a gradient of acetonitrile and 20 mmol/L ammonium acetate （containing 0.1% formic acid）. Oleandrin was detected using electrospray positive ionization （ESI+） with multiple-reaction monitoring （MRM） mode. Results Oleandrin showed excellent linearity in both blood and liver samples in the corresponding linear range （r>0.995 0）, with detection limits 1 ng/mL and 2 ng/g, respectively, extraction recovery rates greater than 70.50%, both intra- and inter-day precisions less than 10.71%, accuracies 98.42%-111.63%, and matrix effects 91.52%-106.39%. The method was successfully applied to a case of suspected oleander poisoning. Oleandrin was detected in the blood, urine, liver tissues, bile, stomach wall tissues and stomach contents of the cadaver, with the content ranging from 65.5 to 29 600.0 ng/mL （ng/g）. Conclusion The method developed in this study is simple and convenient to operate with good selectivity, and is suitable for the analysis of oleandrin in biological samples such as blood and liver tissues, which can provide technical support for forensic identification and clinical diagnosis and treatment of oleander poisoning.

Published
2018
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40. Clustering-Based Particle Swarm Optimization for Electrical Impedance Imaging

Author

Hu, Gang, Chen, Min-you, He, Wei, Zhai, Jin-qian, Hutchison, David, Series editor, Kanade, Takeo, Series editor, Kittler, Josef, Series editor, Kleinberg, Jon M., Series editor, Mattern, Friedemann, Series editor, Mitchell, John C., Series editor, Naor, Moni, Series editor, Nierstrasz, Oscar, Series editor, Pandu Rangan, C., Series editor, Steffen, Bernhard, Series editor, Sudan, Madhu, Series editor, Terzopoulos, Demetri, Series editor, Tygar, Doug, Series editor, Vardi, Moshe Y., Series editor, Weikum, Gerhard, Series editor, Tan, Ying, editor, Shi, Yuhui, editor, Chai, Yi, editor, and Wang, Guoyin, editor

Published
2011
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43. A Reconstruction Method for Electrical Impedance Tomography Using Particle Swarm Optimization

Author

Chen, Min-you, Hu, Gang, He, Wei, Yang, Yan-li, Zhai, Jin-qian, Hutchison, David, Series editor, Kanade, Takeo, Series editor, Kittler, Josef, Series editor, Kleinberg, Jon M., Series editor, Mattern, Friedemann, Series editor, Mitchell, John C., Series editor, Naor, Moni, Series editor, Nierstrasz, Oscar, Series editor, Pandu Rangan, C., Series editor, Steffen, Bernhard, Series editor, Sudan, Madhu, Series editor, Terzopoulos, Demetri, Series editor, Tygar, Doug, Series editor, Vardi, Moshe Y., Series editor, Weikum, Gerhard, Series editor, Li, Kang, editor, Fei, Minrui, editor, Jia, Li, editor, and Irwin, George W., editor

Published
2010
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