1. THROMBOCYTE AND ERYTHROCYTE INDICES IN SEPSIS AND DISSEMINATED INTRAVASCULAR COAGULATION
- Author
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Deniz Akduman, Füsun Cömert, Görkem Mungan, Berrak Guven, Serefden Acikgoz, Murat Can, Vildan Sumbuloglu, Zeynep M. Eskici, and Zonguldak Bülent Ecevit Üniversitesi
- Subjects
medicine.medical_specialty ,Clinical Biochemistry ,Fibrinogen ,Gastroenterology ,Sepsis ,sepsis ,erythrocyte indices ,hemic and lymphatic diseases ,Internal medicine ,medicine ,Coagulation testing ,Platelet ,Mean platelet volume ,disseminated intravascular coagulation ,Disseminated intravascular coagulation ,Prothrombin time ,medicine.diagnostic_test ,business.industry ,platelet (thrombocyte) count ,Biochemistry (medical) ,Platelet Distribution Width ,medicine.disease ,platelet (thrombocyte) indices ,business ,circulatory and respiratory physiology ,medicine.drug - Abstract
WOS: 000296765600010, Sepsis is the inflammatory response against infection. The existence of DIC during sepsis indicates a poor prognosis and coagulation abnormalities and thrombocytopenia may exist. The aim of this study was to investigate platelet and erythrocyte indices in sepsis patients with DIC and without DIC. In both groups coagulation tests, platelet count and indices, erythrocyte count and indices were retrospectively analysed. In the sepsis plus DIC patients the prothrombin time and D-dimer values were found significantly higher and fibrinogen, platelet and plateletcrit were found significantly lower than in the sepsis without DIC group. The ana lysis of mean platelet volume, platelet distribution width, erythrocyte count and indices revealed no significant differences between the two groups. These results showed us that the depression of bone marrow in septic patients with DIC and without DIC did not differ. The activation of the coagulation system might probably be the cause of thrombocyte depletion in DIC.
- Published
- 2012