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350 results on '"Zerbini, Cristiano"'

1. Chronic arthritides and bone structure: focus on rheumatoid arthritis-an update.

Author

Messina, Osvaldo Daniel, Vidal, Maritza, Adami, Giovanni, Vidal, Luis Fernando, Clark, Patricia, Torres, Jorge A Morales, Lems, William, Zerbini, Cristiano, Arguissain, Constanza, Reginster, Jean-Yves, and Lane, Nancy E

Subjects
Bone and Bones, Osteoclasts, Osteoblasts, Humans, Bone Resorption, Arthritis, Rheumatoid, Cytokines, Female, Fractures, Bone, Bone, Bone mass, Fractures, Inflammation, Osteoporosis, Rheumatoid arthritis, Autoimmune Disease, Arthritis, Aging, 2.1 Biological and endogenous factors, Aetiology, Inflammatory and immune system, Musculoskeletal, Clinical Sciences, Public Health and Health Services, Cognitive Sciences, Geriatrics
Abstract

Normal bone remodeling depends of a balance between bone forming cells, osteoblasts and bone resorbing cells, the osteoclasts. In chronic arthritides and some inflammatory and autoimmune diseases such as rheumatoid arthritis, there is a great constellation of cytokines produced by pannus that impair bone formation and stimulate bone resorption by inducing osteoclast differentiation and inhibiting osteoblast maturation. Patients with chronic inflammation have multiple causes that lead to low bone mineral density, osteoporosis and a high risk of fracture including circulating cytokines, impaired mobility, chronic administration of glucocorticoids, low vitamin D levels and post-menopausal status in women, among others. Biologic agents and other therapeutic measures to reach prompt remission might ameliorate these deleterious effects. In many cases, bone acting agents need to be added to conventional treatment to reduce the risk of fractures and to preserve articular integrity and independency for daily living activities. A limited number of studies related to fractures in chronic arthritides were published, and future investigation is needed to determine the risk of fractures and the protective effects of different treatments to reduce this risk.

Published
2023

2. Evidence based Latin American Guidelines of clinical practice on prevention, diagnosis, management and treatment of glucocorticoid induced osteoporosis. A 2022 update: This manuscript has been produced under the auspices of the Committee of National Societies (CNS) and the Committee of Scientific Advisors (CSA) of the International Osteoporosis Foundation (IOF)

Author

Messina, Osvaldo Daniel, Vidal, Maritza, Torres, Jorge A Morales, Vidal, Luis Fernando, Arguissain, Constanza, Pereira, Rosa María, Clark, Patricia, Cerdas Perez, Sonia, Campusano, Claudia, Lazaretti-Castro, Marise, Zerbini, Cristiano, Scali, Juan J., Mendez Sanchez, Lucia, Peralta-Pedrero, Maria L., Cavallo, Andrea, Valdivia Ibarra, Francisco J., and Hernandez Pérez, Talina

Published
2022
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5. Odanacatib for the treatment of postmenopausal osteoporosis: results of the LOFT multicentre, randomised, double-blind, placebo-controlled trial and LOFT Extension study

Author

Mautalén, Carlos Alfredo, Man, Zulema, Zanchetta, Jose Ruben, Magaril, Clelia Haydee, Sambrook, Philip, Reginster, Jean-Yves, Geusens, Piet, Goemaere, Stefan, Albergaria, Ben Hur, Zerbini, Cristiano Augusto de Freitas, Castro, Marise Lazaretti, Gregorio, Luiz Henrique, Stoilov, Rumen, Borissova, Anna-Maria I, Hristozov, Kiril Hristov, Temelkova, Nataliya L, Daskalova, Ivona Kirilova, Kuzmanova, Stefka Ivanova, Yaneva-Bichovska, Daniela, Batalov, Anastas Zgurov, Riedemann, Pablo, Rodriguez Portales, José Adolfo, Tang, Hai, Zhu, hanmin, Zhang, Zhenlin, Chao, Aijun, Hu, Yali, Liu, Zhiming, Lu, Juming, Qiu, Mingcai, Gao, Xin, Zhang, Shaofen, Xu, Ling, Xia, Weibo, Liao, Eryuan, Yang, Wenying, Wu, Wen, Dai, Kerong, Hu, Renming, Jaller, Juan Jose, Cabal, Francisco, Molina, José Fernando, Cure Cure, Carlos A, Yupanqui-Lozno, Hernan, Chalem, Philippe, Londono, John, Abello, Mauricio, Tobias, Edgardo D, Otero, William, Nikolic, Tatjana, Miskic, Blazenka, Stepan, Jan, Vyskocil, Vaclav, Novosad, Libor, Slesinger, Jan, Novosad, Pavel, Vlckova, Erika, Bortlik, Ladislav, Dokoupilova, Eva, Hala, Tomas, Jensen, Jens-Erik Beck, Brixen, Kim Torsten, Langdahl, Bente Lomholt, Schwarz, Peter, Eskildsen, Peter Claes, Eiken, Pia Agnete, Hermann, Anne Pernille, Gram, Jeppe, Schou, Maiken Brix, Alexandersen, Peter, Nedergaard, Bettina, Mejía, Dolores Magdalena, Estrella De Henriquez, Lourdes, Páez, Norka, Velazco, Casimiro, Valter, Ivo, Vahula, Kadri-Liina, Kull, Ingrid, Maasalu, Katre, Chapurlat, Roland, Fardellone, Patrice, Benhamou, Claude Laurent, Roux, Christian, Weryha, Georges, Herkt, Volkmar, Martz, Rene, Nischik, Ruth, Spieler, Wolfgang, Contzen, Christel, Felsenberg, Dieter, Frieling, Isolde, Frahm, Eike, Briones, Henry, Sandoval, Boris, Barrios, Patricia, García, Abraham, Avendaño, Carlos, González, Magdalena, Guerra, Jeremías, Tuna, Maria, Díaz, Olga Marina, Samayoa, Eduardo, López, Edgar, Barrera, José Raúl, Palencia, Mainor, Cifuentes, Mayra, Alvarado, Georgina, López, Miriam, Chavez, Nilmo, Haase, Franklin, Rivera, Ruddy, González, Claudio, Tan, Kathryn, Leung, Ping Chung, Mandalam, Sheshadri, Pitale, Shailesh Umakant, Bantwal, Ganapathi, Ammini, Ariachery Chinamma, Shaikh, Shehla Sajid Akhta, Kanakatte Mylariah, Prasanna Kumar, Dharmalingam, Mala, Mukhopadhyay, Satinath, Jain, Arpit, Singh, Parminder, Shetty, Naresh, Sathyanarayana, Srikanta Shamanna, Shah, Nalini, Chadha, Manoj Dharam, Bhandankar, Rajendra, Velayutham, Kumaravel, Marwah, Sudha, John, Mathew, Sahay, Rakesh Kumar, Adami, Silvano, Nuti, Ranuccio, Bianchi, Gerolamo, Brandi, Maria Luisa, Minisola, Salvatore, Fiore, Carmelo Erio, Rubinacci, Alessandro, Miyajima, Hisayuki, Yamane, Hiroo, Nakatani, Yuji, Okamoto, Sumiaki, Kuroda, Koji, Fujimori, Motoaki, Itabashi, Akira, Katayama, Kuniaki, Nakajo, Satoru, Somekawa, Yoshiaki, Ohsawa, Yoshimitsu, Tajima, Wataru, Mizuno, Katsunori, Mori, Shigeru, Kanabuchi, Takato, Hashizume, Hiroyuki, Oka, Nobuyuki, Hamada, Kazutoshi, Yamaguchi, Motoi, Hirahara, Fumiki, Atobe, Masaaki, Ohtake, Yoshiharu, Ichikawa, Shuichi, Onishi, Tomoyuki, Matsumoto, Kou, Nakamura, Tetsuro, Shirasawa, Eishi, Katayama, Ko, Takahashi, Mitsugu, Oguma, Tadanori, Matsui, Hideo, Katoh, Yoshiharu, Shigenobu, Keiichi, Onishi, Tsutomu, Shibukawa, Masato, Ikeda, Satoshi, Osaka, Kazuhiro, Kanda, Ryosuke, Inobe, Yoshito, Shigenobu, Masaharu, Hasegawa, Morimasa, Yamaji, Tetsuo, Miyazaki, Yu, Ito, Takayasu, Nakamura, Eisuke, Nagai, Shinji, Lim, Sung-Kil, Chung, Yoon-Sok, Shin, Chan-Soo, Min, Yong-Ki, Kim, Ghi Su, Yoon, Hyun Koo, Kang, Moo-Il, Yang, Kyu-Hyun, Park, Hyoung Moo, Kim, In Joo, Chung, Dong Jin, Chung, Ho Yeon, Jaundzeikare, Sandra, Andersone, Dace, Medne, Agita, Yaghi, Yasser, Alekna, Vidmantas, Kasiulevicius, Vytautas, Purtokaite - Labutiniene, Irina, Krasauskiene, Aurelija, Varanaviciene, Jurate, Basijokiene, Vida, Abraitiene, Agne, Radzeviciene, Lina, Walliser, Jesus, García Hernández, Pedro Alberto, Araujo, Maria Frida, Avila Armengol, Hilario Ernesto, De la Peña, Pilar, Tamayo, Juan, Zazueta, Beatriz, Cons, Fidencio, Gilchrist, Nigel Leslie, Reid, Ian Reginald, Leikis, Robert, Jones, Peter, Singh, Joe Gragrath Pradeep, Halse, Johan Inge, Syversen, Unni, Høivik, Hans Olav, Øfjord, Erik Snorre, Gulseth, Hans Christian, Elle, Sigbjørn, Norheim, Paal Dag, Calvo Quiroz, Armando A., Cesar Augusto, Pastor A., León Portocarrero, Manuel Gustavo, Vidal Neira, Luis Fernando, Chavez, Jose, Garro Barrera, Boris, Kuroiwa Sampei, Rita, Luis Fernando, Bellatín V., Oquelis Cabredo, Rogger, Castillo, Sonia, Morales, Agustin Miguel G, Tan, Perry Pua, Leagogo, Liberato Antonio C, Jr., Wang, Edward HM, Li-Yu, Julie T, Sawicki, Andrzej Z, Stasiuk, Barbara, Kania, Grzegorz, Lorenc, Roman, Sidorowicz-Bialynicka, Anna, Szczepanski, Leszek, Franek, Edward, Filip, Rafal, Sekula, Jan, Blicharski, Tomasz, Leszczynski, Piotr, Sewerynek, Ewa, Miazgowski, Tomasz, Milewicz, Andrzej, Dabrowska, Magda, Romaszko, Jerzy, Pluskiewicz, Wojciech, Wojnowski, Lukasz, Codreanu, Catalin, Bolosiu, Horatiu, Ionescu, Ruxandra, Zosin, Ioana, Macovei, Liviu, Bojinca, Mihai, Radulescu, Florin, Pop, Simona, Sarbu, Adrian, Benevolenskaya, Lidia I, Nasonov, Evgeny L, Rozhinskaya, Lyudmila Ya, Oganov, Raphael G, Rodionova, Svetlana S, Shlyakhto, Eugeny Vladimirovich, Trofimov, Vasiliy, Zotkin, Eugeny G, Zazerskaya, Irina E, Grineva, Elena N, Ershova, Olga, Lesnyak, Olga, Ostroumova, Olga D, Malichenko, Svetlana B, Pikhlak, Eduard G, Pilyaev, Valery G, Raskina, Tatiana, Zonova, Elena V, Shirinsky, Valery S, Dimic, Aleksandar N, Cobeljic, Goran, Vujovic, Svetlana, Ellis, Graham Charlston, Lipschitz, Stanley, De Villiers, Tobias Johannes, De Weerd, Albert Jan, Vally, Tasneem, Trinder, Yvonne, Coetsee, Jacobus Ludewikus, Davis, Charles Pierre, Nayiager, Savithree, Hough, Frans Stephanus, Oelofse, Louis F, van der Walt, Eugene, Lombaard, Johannes Jurgens, Blignaut, Suzanne, Govind, Uttam, Fouche, Leon Frederik, Kruger, Dawid Stephanus, Dalmeyer, Johannes Paul, Ferreira, Mada M, Escudero-Contreras, Alejandro, Muñoz Torres, Manuel, Hawkins Carranza, Federico, Perez Castrillon, Jose Luis, García Meijide, Juan Antonio, Jodar Gimeno, Esteban, Palacios Gil-Antuñana, Santiago, de Teresa Parreno, Luis, Martín Mola, Emilio, Alvarez Sanchez, Carmen, Lippuner, Kurt, Tsai, Keh-Sung, Tu, Shih-Te, Chen, Jung-Fu, Lee, Oscar Kuang-Sheng, Hsu, Wen-Wei, Grygorieva, Natalia Viktorivna, Povoroznyuk, Vladyslav Volodymyrovych, Korzh, Mykola Oleksiiovych, Loskutov, Oleksandr Levgeniiovych, Chukov, Andriy Borysovych, Sarmiento, Rex, Thomas, Hawys, Donnachie, Hugh, Pavel-Knox, Irina, Shaw, Hilary, Hassanin, Hana, Abdulhakim, Essam Eldin Ahmed, Savani, Naren, Bachmann, Gloria A, Barrett-Connor, Elizabeth, Binkley, Neil C, Bone, Henry G, Brandon, Donald M, Checketts, Darin David, Fraser, Neil J, Watts, Nelson B, Geller, Steven A, Gimbel, Joseph S, Greenwald, Maria White, Holt, Peter A, Johnston, Cyrus Conrad, Fang, Chien, Kiel, Douglas P, Klashman, David J, Lewiecki, E. Michael, Lowenstein, Mitchell B, McClung, Michael Roy, Nattrass, Susan M, Odio, Alberto, Levengood, Julie, Romaguera, Josefina, Saag, Kenneth G, Sebai, Mohamed Bassam, Snyder, Brian, Kutner, Mark Eliot, Streja, Dan, Schwartz, Elliott P, Christiansen, Mark G, McClung, Michael R, O'Donoghue, Michelle L, Papapoulos, Socrates E, Bone, Henry, Langdahl, Bente, Reid, Ian R, Cavallari, Ilaria, Bonaca, Marc P, Wiviott, Stephen D, de Villiers, Tobias, Ling, Xu, Nakamura, Toshitaka, Rodriguez-Portales, Jose Adolfo, Zanchetta, José, Zerbini, Cristiano A F, Park, Jeong-Gun, Im, KyungAh, Cange, Abby, Grip, Laura T, Heyden, Norman, DaSilva, Carolyn, Cohn, Dosinda, Massaad, Rachid, Scott, Boyd B, Verbruggen, Nadia, Gurner, Deborah, Miller, Deborah L, Blair, Micki L, Polis, Adam B, Stoch, S Aubrey, Santora, Arthur, Lombardi, Antonio, Leung, Albert T, Kaufman, Keith D, and Sabatine, Marc S

Published
2019
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10. Clinical predictors of remission and low disease activity in Latin American early rheumatoid arthritis: data from the GLADAR cohort

Author

Gamboa-Cárdenas, Rocio V, Ugarte-Gil, Manuel F., Loreto, Massardo, Sacnun, Mónica P., Saurit, Verónica, Cardiel, Mario H., Soriano, Enrique R., Pisoni, Cecilia, Galarza-Maldonado, Claudio M., Rios, Carlos, Radominski, Sebastião C., Castelar-Pinheiro, Geraldo da R., Bianchi, Washington Alves, Appenzeller, Simone, da Silveira, Inés Guimarães, de Freitas Zerbini, Cristiano A., Caballero-Uribe, Carlo V., Rojas-Villarraga, Adriana, Guibert-Toledano, Marlene, Ballesteros, Francisco, Montufar, Rubén, Vázquez-Mellado, Janitzia, Esquivel-Valerio, Jorge, De La Torre, Ignacio García, Barile-Fabris, Leonor A., Palezuelos, Fedra Irazoque, Andrade-Ortega, Lilia, Monge, Pablo, Teijeiro, Raquel, Achurra-Castillo, Ángel F., Esteva Spinetti, María H., Alarcón, Graciela S., and Pons-Estel, Bernardo A.

Published
2019
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11. Effects of teriparatide and risedronate on new fractures in post-menopausal women with severe osteoporosis (VERO): a multicentre, double-blind, double-dummy, randomised controlled trial

Author

Kendler, David L, Marin, Fernando, Zerbini, Cristiano A F, Russo, Luis A, Greenspan, Susan L, Zikan, Vit, Bagur, Alicia, Malouf-Sierra, Jorge, Lakatos, Péter, Fahrleitner-Pammer, Astrid, Lespessailles, Eric, Minisola, Salvatore, Body, Jean Jacques, Geusens, Piet, Möricke, Rüdiger, and López-Romero, Pedro

Published
2018
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12. Relationship between bone mineral density changes with denosumab treatment and risk reduction for vertebral and nonvertebral fractures

Author

Austin, Matthew, Yang, Yu‐Ching, Vittinghoff, Eric, Adami, Silvano, Boonen, Steven, Bauer, Douglas C, Bianchi, Gerolamo, Bolognese, Michael A, Christiansen, Claus, Eastell, Richard, Grauer, Andreas, Hawkins, Federico, Kendler, David L, Oliveri, Beatriz, McClung, Michael R, Reid, Ian R, Siris, Ethel S, Zanchetta, Jose, Zerbini, Cristiano AF, Libanati, Cesar, Cummings, Steven R, and Trial, for the FREEDOM

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Clinical Research, Osteoporosis, Physical Injury - Accidents and Adverse Effects, Musculoskeletal, Absorptiometry, Photon, Aged, Aged, 80 and over, Antibodies, Monoclonal, Antibodies, Monoclonal, Humanized, Bone Density, Bone Density Conservation Agents, Denosumab, Double-Blind Method, Female, Fractures, Bone, Humans, Middle Aged, Placebos, Risk Reduction Behavior, Spinal Fractures, DENOSUMAB, BONE MINERAL DENSITY, FRACTURE, SURROGATE, PERCENT OF TREATMENT EFFECT EXPLAINED, FREEDOM Trial, Biological Sciences, Engineering, Medical and Health Sciences, Anatomy & Morphology, Biological sciences, Biomedical and clinical sciences
Abstract

Dual-energy X-ray absorptiometric bone mineral density (DXA BMD) is a strong predictor of fracture risk in untreated patients. However, previous patient-level studies suggest that BMD changes explain little of the fracture risk reduction observed with osteoporosis treatment. We investigated the relevance of DXA BMD changes as a predictor for fracture risk reduction using data from the FREEDOM trial, which randomly assigned placebo or denosumab 60 mg every 6 months to 7808 women aged 60 to 90 years with a spine or total hip BMD T-score < -2.5 and not < -4.0. We took a standard approach to estimate the percent of treatment effect explained using percent changes in BMD at a single visit (months 12, 24, or 36). We also applied a novel approach using estimated percent changes in BMD from baseline at the time of fracture occurrence (time-dependent models). Denosumab significantly increased total hip BMD by 3.2%, 4.4%, and 5.0% at 12, 24, and 36 months, respectively. Denosumab decreased the risk of new vertebral fractures by 68% (p < 0.0001) and nonvertebral fracture by 20% (p = 0.01) over 36 months. Regardless of the method used, the change in total hip BMD explained a considerable proportion of the effect of denosumab in reducing new or worsening vertebral fracture risk (35% [95% confidence interval (CI): 20%-61%] and 51% [95% CI: 39%-66%] accounted for by percent change at month 36 and change in time-dependent BMD, respectively) and explained a considerable amount of the reduction in nonvertebral fracture risk (87% [95% CI: 35% - >100%] and 72% [95% CI: 24% - >100%], respectively). Previous patient-level studies may have underestimated the strength of the relationship between BMD change and the effect of treatment on fracture risk or this relationship may be unique to denosumab.

Published
2012

14. Brazilian guidelines for the diagnosis and treatment of postmenopausal osteoporosis

Author

Radominski, Sebastião Cézar, Bernardo, Wanderley, Paula, Ana Patrícia de, Albergaria, Ben-Hur, Moreira, Caio, Fernandes, Cesar Eduardo, Castro, Charlles H.M., Zerbini, Cristiano Augusto de Freitas, Domiciano, Diogo S., Mendonça, Laura M.C., Pompei, Luciano de Melo, Bezerra, Mailze Campos, Loures, Marco Antônio R., Wender, Maria Celeste Osório, Lazaretti-Castro, Marise, Pereira, Rosa M.R., Maeda, Sergio Setsuo, Szejnfeld, Vera Lúcia, and Borba, Victoria Z.C.

Published
2017
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16. Diretrizes brasileiras para o diagnóstico e tratamento da osteoporose em mulheres na pós‐menopausa

Author

Radominski, Sebastião Cezar, Bernardo, Wanderley, Paula, Ana Patrícia de, Albergaria, Ben‐Hur, Moreira, Caio, Fernandes, Cesar Eduardo, Castro, Charlles H.M., Zerbini, Cristiano Augusto de Freitas, Domiciano, Diogo S., Mendonça, Laura M.C., Pompei, Luciano de Melo, Bezerra, Mailze Campos, Loures, Marco Antônio R., Wender, Maria Celeste Osório, Lazaretti‐Castro, Marise, Pereira, Rosa M.R., Maeda, Sergio Setsuo, Szejnfeld, Vera Lúcia, and Borba, Victoria Z.C.

Published
2017
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18. Burden of rheumatoid arthritis on patients’ work productivity and quality of life

Author

Xavier, Ricardo Machado, Zerbini, Cristiano Augusto Freitas, Pollak, Daniel Feldman, Morales-Torres, Jorge Luis Alberto, Chalem, Philippe, Restrepo, José Fernando Molina, Duhau, Javier Arnaldo, Amado, Jacqueline Rodríguez, Abello, Maurício, de la Vega, Maria Celina, Dávila, Adriana Pérez, Biegun, Priscila Martin, Arruda, Maysa Silva, and Ramos-Remus, Cesar

Published
2019
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20. Correction to: Clinical predictors of remission and low disease activity in Latin American early rheumatoid arthritis: data from the GLADAR cohort

Author

Gamboa-Cárdenas, Rocio V, Ugarte-Gil, Manuel F., Massardo, Loreto, Sacnun, Mónica P., Saurit, Verónica, Cardiel, Mario H., Soriano, Enrique R., Pisoni, Cecilia, Galarza-Maldonado, Claudio M., Rios, Carlos, Radominski, Sebastião C., Castelar-Pinheiro, Geraldo da R., Bianchi, Washington Alves, Appenzeller, Simone, da Silveira, Inés Guimarães, de Freitas Zerbini, Cristiano A., Caballero-Uribe, Carlo V., Rojas-Villarraga, Adriana, Guibert-Toledano, Marlene, Ballesteros, Francisco, Montufar, Rubén, Vázquez-Mellado, Janitzia, Esquivel-Valerio, Jorge, De La Torre, Ignacio García, Barile-Fabris, Leonor A., Palezuelos, Fedra Irazoque, Andrade-Ortega, Lilia, Monge, Pablo, Teijeiro, Raquel, Achurra-Castillo, Ángel F., Esteva Spinetti, María H., Alarcón, Graciela S., and Pons-Estel, Bernardo A.

Published
2019
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23. Plain language summary of Pfizer-BioNTech BNT162b2 COVID-19 vaccine safety in participants 16 years or older and protection against COVID-19 in participants 12 years or older

Author

Thomas, Stephen J, primary, Moreira, Edson D, additional, Kitchin, Nicholas, additional, Absalon, Judith, additional, Gurtman, Alejandra, additional, Lockhart, Stephen, additional, Perez, John L, additional, Marc, Gonzalo Pérez, additional, Polack, Fernando P, additional, Zerbini, Cristiano, additional, Bailey, Ruth, additional, Swanson, Kena A, additional, Xu, Xia, additional, Roychoudhury, Satrajit, additional, Koury, Kenneth, additional, Bouguermouh, Salim, additional, Kalina, Warren V, additional, Cooper, David, additional, Frenck, Robert W, additional, Hammitt, Laura L, additional, Türeci, Özlem, additional, Nell, Haylene, additional, Schaefer, Axel, additional, Ünal, Serhat, additional, Yang, Qi, additional, Liberator, Paul, additional, Tresnan, Dina B, additional, Mather, Susan, additional, Dormitzer, Philip R, additional, Şahin, Uğur, additional, Gruber, William C, additional, and Jansen, Kathrin U, additional

Published
2022
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25. Definition and management of very high fracture risk in women with postmenopausal osteoporosis: a position statement from the Brazilian Society of Endocrinology and Metabolism (SBEM) and the Brazilian Association of Bone Assessment and Metabolism (ABRASSO)

Author

Silva, Barbara C., primary, Madeira, Miguel, additional, d’Alva, Catarina Brasil, additional, Maeda, Sergio Setsuo, additional, Holanda, Narriane Chaves Pereira de, additional, Ohe, Monique Nakayama, additional, Szejnfeld, Vera, additional, Zerbini, Cristiano A. F., additional, Paula, Francisco José Albuquerque de, additional, and Bandeira, Francisco, additional

Published
2022
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26. Maintenance of remission with combination etanercept–DMARD therapy versus DMARDs alone in active rheumatoid arthritis: results of an international treat-to-target study conducted in regions with limited biologic access

Author

Pavelka, Karel, Akkoç, Nurullah, Al-Maini, Mustafa, Zerbini, Cristiano A. F., Karateev, Dmitry E., Nasonov, Evgeny L., Rahman, Mahboob U., Pedersen, Ronald, Dinh, Andrew, Shen, Qi, Vasilescu, Radu, Kotak, Sameer, Mahgoub, Ehab, and Vlahos, Bonnie

Published
2017
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28. Safety and Efficacy of a Third Dose of BNT162b2 Covid-19 Vaccine

Author

Moreira, Edson D., primary, Kitchin, Nicholas, additional, Xu, Xia, additional, Dychter, Samuel S., additional, Lockhart, Stephen, additional, Gurtman, Alejandra, additional, Perez, John L., additional, Zerbini, Cristiano, additional, Dever, Michael E., additional, Jennings, Timothy W., additional, Brandon, Donald M., additional, Cannon, Kevin D., additional, Koren, Michael J., additional, Denham, Douglas S., additional, Berhe, Mezgebe, additional, Fitz-Patrick, David, additional, Hammitt, Laura L., additional, Klein, Nicola P., additional, Nell, Haylene, additional, Keep, Georgina, additional, Wang, Xingbin, additional, Koury, Kenneth, additional, Swanson, Kena A., additional, Cooper, David, additional, Lu, Claire, additional, Türeci, Özlem, additional, Lagkadinou, Eleni, additional, Tresnan, Dina B., additional, Dormitzer, Philip R., additional, Şahin, Uğur, additional, Gruber, William C., additional, and Jansen, Kathrin U., additional

Published
2022
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29. Baricitinib, Methotrexate, or Combination in Patients With Rheumatoid Arthritis and No or Limited Prior Disease‐Modifying Antirheumatic Drug Treatment

Author

Fleischmann, Roy, Schiff, Michael, van der Heijde, Désirée, RamosRemus, Cesar, Spindler, Alberto, Stanislav, Marina, Zerbini, Cristiano A. F., Gurbuz, Sirel, Dickson, Christina, de Bono, Stephanie, Schlichting, Douglas, Beattie, Scott, Kuo, WenLing, Rooney, Terence, Macias, William, and Takeuchi, Tsutomu

Published
2017
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30. Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine through 6 Months

Author

Thomas, Stephen J., primary, Moreira, Edson D., additional, Kitchin, Nicholas, additional, Absalon, Judith, additional, Gurtman, Alejandra, additional, Lockhart, Stephen, additional, Perez, John L., additional, Pérez Marc, Gonzalo, additional, Polack, Fernando P., additional, Zerbini, Cristiano, additional, Bailey, Ruth, additional, Swanson, Kena A., additional, Xu, Xia, additional, Roychoudhury, Satrajit, additional, Koury, Kenneth, additional, Bouguermouh, Salim, additional, Kalina, Warren V., additional, Cooper, David, additional, Frenck, Robert W., additional, Hammitt, Laura L., additional, Türeci, Özlem, additional, Nell, Haylene, additional, Schaefer, Axel, additional, Ünal, Serhat, additional, Yang, Qi, additional, Liberator, Paul, additional, Tresnan, Dina B., additional, Mather, Susan, additional, Dormitzer, Philip R., additional, Şahin, Uğur, additional, Gruber, William C., additional, and Jansen, Kathrin U., additional

Published
2021
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31. Romosozumab improves lumbar spine bone mass and bone strength parameters relative to alendronate in postmenopausal women: results from the Active-Controlled Fracture Study in Postmenopausal Women With Osteoporosis at High Risk (ARCH) trial

Author

Brown, Jacques P., primary, Engelke, Klaus, additional, Keaveny, Tony M., additional, Chines, Arkadi, additional, Chapurlat, Roland, additional, Foldes, A. Joseph, additional, Nogues, Xavier, additional, Civitelli, Roberto, additional, De Villiers, Tobias, additional, Massari, Fabio, additional, Zerbini, Cristiano A.F., additional, Wang, Zhenxun, additional, Oates, Mary K., additional, Recknor, Christopher, additional, and Libanati, Cesar, additional

Published
2021
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32. Metodologia para a avaliação da atividade física habitual em homens com 50 anos ou mais

Author

Florindo Alex Antonio, Latorre Maria do Rosario Dias de Oliveira, Jaime Patrícia Constante, Tanaka Tomoe, and Zerbini Cristiano Augusto de Freitas

Subjects
Exercício, Avaliação, Métodos, Questionários, Saúde do idoso, Densidade óssea, Atividade física habitual, Public aspects of medicine, RA1-1270
Abstract

OBJETIVO: Descrever a metodologia de avaliação da atividade física habitual, utilizanda em uma pesquisa em população masculina, por meio de um questionário já validado. MÉTODOS: O questionário de atividade física habitual de Baecke, traduzido para a língua portuguesa e, a seguir, foi realizado o back translation. Em sua versão final o questionário foi aplicado em estudo epidemiológico transversal, realizado com 326 homens com idade igual ou superior a 50 anos. A consistência interna entre as questões foi analisada pelo a de Cronbach e foram calculados os coeficientes de correlação de Spearman entre os escores de atividade física habitual, bem como os coeficientes de correlação parcial, ajustados por idade, índice de massa corporal e escolaridade. RESULTADOS: A consistência interna mostrou-se satisfatória nas magnitudes de atividade física ocupacional e exercícios físicos no lazer. Foram obtidas correlações significativas entre todos os escores de atividades físicas com o escore total de atividade física habitual, independente da idade, escolaridade e índice de massa corporal. CONCLUSÕES: O questionário Baecke mostrou-se um instrumento prático para avaliar a atividade física habitual, aliando rapidez na aplicabilidade e facilidade no entendimento para as respostas, sendo indicado para estudos epidemiológicos no Brasil.

Published
2004

35. Odanacatib for the treatment of postmenopausal osteoporosis: results of the LOFT multicentre, randomised, double-blind, placebo-controlled trial and LOFT Extension study

Author

McClung, Michael R, primary, O'Donoghue, Michelle L, additional, Papapoulos, Socrates E, additional, Bone, Henry, additional, Langdahl, Bente, additional, Saag, Kenneth G, additional, Reid, Ian R, additional, Kiel, Douglas P, additional, Cavallari, Ilaria, additional, Bonaca, Marc P, additional, Wiviott, Stephen D, additional, de Villiers, Tobias, additional, Ling, Xu, additional, Lippuner, Kurt, additional, Nakamura, Toshitaka, additional, Reginster, Jean-Yves, additional, Rodriguez-Portales, Jose Adolfo, additional, Roux, Christian, additional, Zanchetta, José, additional, Zerbini, Cristiano A F, additional, Park, Jeong-Gun, additional, Im, KyungAh, additional, Cange, Abby, additional, Grip, Laura T, additional, Heyden, Norman, additional, DaSilva, Carolyn, additional, Cohn, Dosinda, additional, Massaad, Rachid, additional, Scott, Boyd B, additional, Verbruggen, Nadia, additional, Gurner, Deborah, additional, Miller, Deborah L, additional, Blair, Micki L, additional, Polis, Adam B, additional, Stoch, S Aubrey, additional, Santora, Arthur, additional, Lombardi, Antonio, additional, Leung, Albert T, additional, Kaufman, Keith D, additional, Sabatine, Marc S, additional, Mautalén, Carlos Alfredo, additional, Man, Zulema, additional, Zanchetta, Jose Ruben, additional, Magaril, Clelia Haydee, additional, Sambrook, Philip, additional, Geusens, Piet, additional, Goemaere, Stefan, additional, Albergaria, Ben Hur, additional, Zerbini, Cristiano Augusto de Freitas, additional, Castro, Marise Lazaretti, additional, Gregorio, Luiz Henrique, additional, Stoilov, Rumen, additional, Borissova, Anna-Maria I, additional, Hristozov, Kiril Hristov, additional, Temelkova, Nataliya L, additional, Daskalova, Ivona Kirilova, additional, Kuzmanova, Stefka Ivanova, additional, Yaneva-Bichovska, Daniela, additional, Batalov, Anastas Zgurov, additional, Riedemann, Pablo, additional, Rodriguez Portales, José Adolfo, additional, Tang, Hai, additional, Zhu, hanmin, additional, Zhang, Zhenlin, additional, Chao, Aijun, additional, Hu, Yali, additional, Liu, Zhiming, additional, Lu, Juming, additional, Qiu, Mingcai, additional, Gao, Xin, additional, Zhang, Shaofen, additional, Xu, Ling, additional, Xia, Weibo, additional, Liao, Eryuan, additional, Yang, Wenying, additional, Wu, Wen, additional, Dai, Kerong, additional, Hu, Renming, additional, Jaller, Juan Jose, additional, Cabal, Francisco, additional, Molina, José Fernando, additional, Cure Cure, Carlos A, additional, Yupanqui-Lozno, Hernan, additional, Chalem, Philippe, additional, Londono, John, additional, Abello, Mauricio, additional, Tobias, Edgardo D, additional, Otero, William, additional, Nikolic, Tatjana, additional, Miskic, Blazenka, additional, Stepan, Jan, additional, Vyskocil, Vaclav, additional, Novosad, Libor, additional, Slesinger, Jan, additional, Novosad, Pavel, additional, Vlckova, Erika, additional, Bortlik, Ladislav, additional, Dokoupilova, Eva, additional, Hala, Tomas, additional, Jensen, Jens-Erik Beck, additional, Brixen, Kim Torsten, additional, Langdahl, Bente Lomholt, additional, Schwarz, Peter, additional, Eskildsen, Peter Claes, additional, Eiken, Pia Agnete, additional, Hermann, Anne Pernille, additional, Gram, Jeppe, additional, Schou, Maiken Brix, additional, Alexandersen, Peter, additional, Nedergaard, Bettina, additional, Mejía, Dolores Magdalena, additional, Estrella De Henriquez, Lourdes, additional, Páez, Norka, additional, Velazco, Casimiro, additional, Valter, Ivo, additional, Vahula, Kadri-Liina, additional, Kull, Ingrid, additional, Maasalu, Katre, additional, Chapurlat, Roland, additional, Fardellone, Patrice, additional, Benhamou, Claude Laurent, additional, Weryha, Georges, additional, Herkt, Volkmar, additional, Martz, Rene, additional, Nischik, Ruth, additional, Spieler, Wolfgang, additional, Contzen, Christel, additional, Felsenberg, Dieter, additional, Frieling, Isolde, additional, Frahm, Eike, additional, Briones, Henry, additional, Sandoval, Boris, additional, Barrios, Patricia, additional, García, Abraham, additional, Avendaño, Carlos, additional, González, Magdalena, additional, Guerra, Jeremías, additional, Tuna, Maria, additional, Díaz, Olga Marina, additional, Samayoa, Eduardo, additional, López, Edgar, additional, Barrera, José Raúl, additional, Palencia, Mainor, additional, Cifuentes, Mayra, additional, Alvarado, Georgina, additional, López, Miriam, additional, Chavez, Nilmo, additional, Haase, Franklin, additional, Rivera, Ruddy, additional, González, Claudio, additional, Tan, Kathryn, additional, Leung, Ping Chung, additional, Mandalam, Sheshadri, additional, Pitale, Shailesh Umakant, additional, Bantwal, Ganapathi, additional, Ammini, Ariachery Chinamma, additional, Shaikh, Shehla Sajid Akhta, additional, Kanakatte Mylariah, Prasanna Kumar, additional, Dharmalingam, Mala, additional, Mukhopadhyay, Satinath, additional, Jain, Arpit, additional, Singh, Parminder, additional, Shetty, Naresh, additional, Sathyanarayana, Srikanta Shamanna, additional, Shah, Nalini, additional, Chadha, Manoj Dharam, additional, Bhandankar, Rajendra, additional, Velayutham, Kumaravel, additional, Marwah, Sudha, additional, John, Mathew, additional, Sahay, Rakesh Kumar, additional, Adami, Silvano, additional, Nuti, Ranuccio, additional, Bianchi, Gerolamo, additional, Brandi, Maria Luisa, additional, Minisola, Salvatore, additional, Fiore, Carmelo Erio, additional, Rubinacci, Alessandro, additional, Miyajima, Hisayuki, additional, Yamane, Hiroo, additional, Nakatani, Yuji, additional, Okamoto, Sumiaki, additional, Kuroda, Koji, additional, Fujimori, Motoaki, additional, Itabashi, Akira, additional, Katayama, Kuniaki, additional, Nakajo, Satoru, additional, Somekawa, Yoshiaki, additional, Ohsawa, Yoshimitsu, additional, Tajima, Wataru, additional, Mizuno, Katsunori, additional, Mori, Shigeru, additional, Kanabuchi, Takato, additional, Hashizume, Hiroyuki, additional, Oka, Nobuyuki, additional, Hamada, Kazutoshi, additional, Yamaguchi, Motoi, additional, Hirahara, Fumiki, additional, Atobe, Masaaki, additional, Ohtake, Yoshiharu, additional, Ichikawa, Shuichi, additional, Onishi, Tomoyuki, additional, Matsumoto, Kou, additional, Nakamura, Tetsuro, additional, Shirasawa, Eishi, additional, Katayama, Ko, additional, Takahashi, Mitsugu, additional, Oguma, Tadanori, additional, Matsui, Hideo, additional, Katoh, Yoshiharu, additional, Shigenobu, Keiichi, additional, Onishi, Tsutomu, additional, Shibukawa, Masato, additional, Ikeda, Satoshi, additional, Osaka, Kazuhiro, additional, Kanda, Ryosuke, additional, Inobe, Yoshito, additional, Shigenobu, Masaharu, additional, Hasegawa, Morimasa, additional, Yamaji, Tetsuo, additional, Miyazaki, Yu, additional, Ito, Takayasu, additional, Nakamura, Eisuke, additional, Nagai, Shinji, additional, Lim, Sung-Kil, additional, Chung, Yoon-Sok, additional, Shin, Chan-Soo, additional, Min, Yong-Ki, additional, Kim, Ghi Su, additional, Yoon, Hyun Koo, additional, Kang, Moo-Il, additional, Yang, Kyu-Hyun, additional, Park, Hyoung Moo, additional, Kim, In Joo, additional, Chung, Dong Jin, additional, Chung, Ho Yeon, additional, Jaundzeikare, Sandra, additional, Andersone, Dace, additional, Medne, Agita, additional, Yaghi, Yasser, additional, Alekna, Vidmantas, additional, Kasiulevicius, Vytautas, additional, Purtokaite - Labutiniene, Irina, additional, Krasauskiene, Aurelija, additional, Varanaviciene, Jurate, additional, Basijokiene, Vida, additional, Abraitiene, Agne, additional, Radzeviciene, Lina, additional, Walliser, Jesus, additional, García Hernández, Pedro Alberto, additional, Araujo, Maria Frida, additional, Avila Armengol, Hilario Ernesto, additional, De la Peña, Pilar, additional, Tamayo, Juan, additional, Zazueta, Beatriz, additional, Cons, Fidencio, additional, Gilchrist, Nigel Leslie, additional, Reid, Ian Reginald, additional, Leikis, Robert, additional, Jones, Peter, additional, Singh, Joe Gragrath Pradeep, additional, Halse, Johan Inge, additional, Syversen, Unni, additional, Høivik, Hans Olav, additional, Øfjord, Erik Snorre, additional, Gulseth, Hans Christian, additional, Elle, Sigbjørn, additional, Norheim, Paal Dag, additional, Calvo Quiroz, Armando A., additional, Cesar Augusto, Pastor A., additional, León Portocarrero, Manuel Gustavo, additional, Vidal Neira, Luis Fernando, additional, Chavez, Jose, additional, Garro Barrera, Boris, additional, Kuroiwa Sampei, Rita, additional, Luis Fernando, Bellatín V., additional, Oquelis Cabredo, Rogger, additional, Castillo, Sonia, additional, Morales, Agustin Miguel G, additional, Tan, Perry Pua, additional, Leagogo, Liberato Antonio C, additional, Wang, Edward HM, additional, Li-Yu, Julie T, additional, Sawicki, Andrzej Z, additional, Stasiuk, Barbara, additional, Kania, Grzegorz, additional, Lorenc, Roman, additional, Sidorowicz-Bialynicka, Anna, additional, Szczepanski, Leszek, additional, Franek, Edward, additional, Filip, Rafal, additional, Sekula, Jan, additional, Blicharski, Tomasz, additional, Leszczynski, Piotr, additional, Sewerynek, Ewa, additional, Miazgowski, Tomasz, additional, Milewicz, Andrzej, additional, Dabrowska, Magda, additional, Romaszko, Jerzy, additional, Pluskiewicz, Wojciech, additional, Wojnowski, Lukasz, additional, Codreanu, Catalin, additional, Bolosiu, Horatiu, additional, Ionescu, Ruxandra, additional, Zosin, Ioana, additional, Macovei, Liviu, additional, Bojinca, Mihai, additional, Radulescu, Florin, additional, Pop, Simona, additional, Sarbu, Adrian, additional, Benevolenskaya, Lidia I, additional, Nasonov, Evgeny L, additional, Rozhinskaya, Lyudmila Ya, additional, Oganov, Raphael G, additional, Rodionova, Svetlana S, additional, Shlyakhto, Eugeny Vladimirovich, additional, Trofimov, Vasiliy, additional, Zotkin, Eugeny G, additional, Zazerskaya, Irina E, additional, Grineva, Elena N, additional, Ershova, Olga, additional, Lesnyak, Olga, additional, Ostroumova, Olga D, additional, Malichenko, Svetlana B, additional, Pikhlak, Eduard G, additional, Pilyaev, Valery G, additional, Raskina, Tatiana, additional, Zonova, Elena V, additional, Shirinsky, Valery S, additional, Dimic, Aleksandar N, additional, Cobeljic, Goran, additional, Vujovic, Svetlana, additional, Ellis, Graham Charlston, additional, Lipschitz, Stanley, additional, De Villiers, Tobias Johannes, additional, De Weerd, Albert Jan, additional, Vally, Tasneem, additional, Trinder, Yvonne, additional, Coetsee, Jacobus Ludewikus, additional, Davis, Charles Pierre, additional, Nayiager, Savithree, additional, Hough, Frans Stephanus, additional, Oelofse, Louis F, additional, van der Walt, Eugene, additional, Lombaard, Johannes Jurgens, additional, Blignaut, Suzanne, additional, Govind, Uttam, additional, Fouche, Leon Frederik, additional, Kruger, Dawid Stephanus, additional, Dalmeyer, Johannes Paul, additional, Ferreira, Mada M, additional, Escudero-Contreras, Alejandro, additional, Muñoz Torres, Manuel, additional, Hawkins Carranza, Federico, additional, Perez Castrillon, Jose Luis, additional, García Meijide, Juan Antonio, additional, Jodar Gimeno, Esteban, additional, Palacios Gil-Antuñana, Santiago, additional, de Teresa Parreno, Luis, additional, Martín Mola, Emilio, additional, Alvarez Sanchez, Carmen, additional, Tsai, Keh-Sung, additional, Tu, Shih-Te, additional, Chen, Jung-Fu, additional, Lee, Oscar Kuang-Sheng, additional, Hsu, Wen-Wei, additional, Grygorieva, Natalia Viktorivna, additional, Povoroznyuk, Vladyslav Volodymyrovych, additional, Korzh, Mykola Oleksiiovych, additional, Loskutov, Oleksandr Levgeniiovych, additional, Chukov, Andriy Borysovych, additional, Sarmiento, Rex, additional, Thomas, Hawys, additional, Donnachie, Hugh, additional, Pavel-Knox, Irina, additional, Shaw, Hilary, additional, Hassanin, Hana, additional, Abdulhakim, Essam Eldin Ahmed, additional, Savani, Naren, additional, Bachmann, Gloria A, additional, Barrett-Connor, Elizabeth, additional, Binkley, Neil C, additional, Bone, Henry G, additional, Brandon, Donald M, additional, Checketts, Darin David, additional, Fraser, Neil J, additional, Watts, Nelson B, additional, Geller, Steven A, additional, Gimbel, Joseph S, additional, Greenwald, Maria White, additional, Holt, Peter A, additional, Johnston, Cyrus Conrad, additional, Fang, Chien, additional, Klashman, David J, additional, Lewiecki, E. Michael, additional, Lowenstein, Mitchell B, additional, McClung, Michael Roy, additional, Nattrass, Susan M, additional, Odio, Alberto, additional, Levengood, Julie, additional, Romaguera, Josefina, additional, Sebai, Mohamed Bassam, additional, Snyder, Brian, additional, Kutner, Mark Eliot, additional, Streja, Dan, additional, Schwartz, Elliott P, additional, and Christiansen, Mark G, additional

Published
2019
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38. Patient-reported outcomes from a randomized, double-blind, placebo controlled, phase III study of baricitinib versus placebo in patients with moderately to severely active rheumatoid arthritis and an inadequate response to methotrexate therapy: results from the RA-BALANCE study

Author

Yang, Yue, primary, Xu, Jianhua, additional, Xu, Jian, additional, Li, Xingfu, additional, Hu, Jiankang, additional, Li, Xiangpei, additional, Zhang, Xiao, additional, He, Dongyi, additional, Bao, Chunde, additional, Li, Zhijun, additional, Wang, Guochun, additional, Zerbini, Cristiano A. F., additional, Spindler, Alberto J., additional, Kannowski, Carol L., additional, Wu, Hanjun, additional, Ji, Fei, additional, Zhan, Lujing, additional, Liu, Mengru, additional, and Li, Zhanguo, additional

Published
2021
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40. Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine

Author

Polack, Fernando P., primary, Thomas, Stephen J., additional, Kitchin, Nicholas, additional, Absalon, Judith, additional, Gurtman, Alejandra, additional, Lockhart, Stephen, additional, Perez, John L., additional, Pérez Marc, Gonzalo, additional, Moreira, Edson D., additional, Zerbini, Cristiano, additional, Bailey, Ruth, additional, Swanson, Kena A., additional, Roychoudhury, Satrajit, additional, Koury, Kenneth, additional, Li, Ping, additional, Kalina, Warren V., additional, Cooper, David, additional, Frenck, Robert W., additional, Hammitt, Laura L., additional, Türeci, Özlem, additional, Nell, Haylene, additional, Schaefer, Axel, additional, Ünal, Serhat, additional, Tresnan, Dina B., additional, Mather, Susan, additional, Dormitzer, Philip R., additional, Şahin, Uğur, additional, Jansen, Kathrin U., additional, and Gruber, William C., additional

Published
2020
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41. Switching between Janus kinase inhibitor upadacitinib and adalimumab following insufficient response: efficacy and safety in patients with rheumatoid arthritis

Author

Fleischmann, Roy M, primary, Blanco, Ricardo, additional, Hall, Stephen, additional, Thomson, Glen T D, additional, Van den Bosch, Filip E, additional, Zerbini, Cristiano, additional, Bessette, Louis, additional, Enejosa, Jeffrey, additional, Li, Yihan, additional, Song, Yanna, additional, DeMasi, Ryan, additional, and Song, In-Ho, additional

Published
2020
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42. Safety profile of upadacitinib in rheumatoid arthritis: integrated analysis from the SELECT phase III clinical programme

Author

Cohen, Stanley B, primary, van Vollenhoven, Ronald F, additional, Winthrop, Kevin L, additional, Zerbini, Cristiano A F, additional, Tanaka, Yoshiya, additional, Bessette, Louis, additional, Zhang, Ying, additional, Khan, Nasser, additional, Hendrickson, Barbara, additional, Enejosa, Jeffrey V, additional, and Burmester, Gerd R, additional

Published
2020
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43. Romosozumab improves lumbar spine BMD and bone strength greater than alendronate as assessed by quantitative computed tomography and finite element analysis in the ARCH trial

Author

Brown, Jacques P., primary, Chines, Arkadi, additional, Chapurlat, Roland, additional, Foldes, Joseph, additional, Nogues, Xavier, additional, Civitelli, Roberto, additional, De Villiers, Tobias, additional, Massari, Fabio, additional, Zerbini, Cristiano, additional, Yang, Wenjing, additional, Recknor, Chris, additional, and Libanati, Cesar, additional

Published
2020
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45. Tofacitinib (CP-690,550) in patients with rheumatoid arthritis receiving methotrexate: Twelve-month data from a twenty-four–month phase III randomized radiographic study

Author

van der Heijde, Désirée, Tanaka, Yoshiya, Fleischmann, Roy, Keystone, Edward, Kremer, Joel, Zerbini, Cristiano, Cardiel, Mario H., Cohen, Stanley, Nash, Peter, Song, Yeong-Wook, Tegzová, Dana, Wyman, Bradley T., Gruben, David, Benda, Birgitta, Wallenstein, Gene, Krishnaswami, Sriram, Zwillich, Samuel H., Bradley, John D., and Connell, Carol A.

Published
2013
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46. Past and present habitual physical activity and its relationship with bone mineral density in men aged 50 years and older in Brazil

Author

Florindo, Alex A., Latorre, Maria do Rosario D.O., Jaime, Patricia C., Tanaka, Tomoe, Pippa, Maria G.B., and Zerbini, Cristiano A.F.

Subjects
Gerontology -- Research, Exercise -- Physiological aspects, Bones -- Density, Health, Seniors
Abstract

Background. The aim of this study was to determine the relationship between habitual physical activity (HPA) during life and bone mineral density (BMD) in men aged 50 years and older. Methods. A total of 326 men aged 50 years and older, volunteers living in Sao Paulo city, Brazil, were studied. BMD was measured in the whole body, femoral neck, Ward's triangle, trochanter, and lumbar spine (L2-L4) with a dual-energy x-ray absorptiometer. The HPA data were collected with questionnaires inquiring about physical exercise and occupational physical activity in the past and during the past 12 months and leisure and locomotor physical activity in the preceding 12 months. The relationship between BMD and HPA was analyzed using multiple linear regression models adjusted for age and body mass index (BMI). Results. Practice of physical exercise in the past 10-20 years and leisure and locomotor physical activity in the preceding 12 months showed a significant positive correlation with BMD of whole body, femoral neck, trochanter, and lumbar spine, and this association was independent of age and BMI. Conclusions. HPA can contribute to preserving BMD in men aged 50 years and older in Brazil, when it is practiced in the past 10-20 years and even in the present.

Published
2002

50. Efficacy and Safety of Long‐Term Baricitinib With and Without Methotrexate for the Treatment of Rheumatoid Arthritis: Experience With Baricitinib Monotherapy Continuation or After Switching From Methotrexate Monotherapy or Baricitinib Plus Methotrexate

Author

Fleischmann, Roy, primary, Takeuchi, Tsutomu, additional, Schiff, Michael, additional, Schlichting, Douglas, additional, Xie, Li, additional, Issa, Maher, additional, Stoykov, Ivaylo, additional, Lisse, Jeffrey, additional, Martinez‐Osuna, Pindaro, additional, Rooney, Terence, additional, and Zerbini, Cristiano A. F., additional

Published
2020
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