223 results on '"Zenone, Thierry"'
Search Results
2. Clinical value of a [18F]-FDG PET-CT muscle-to-muscle SUV ratio for the diagnosis of active dermatomyositis
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Martis, Nihal, Viau, Philippe, Zenone, Thierry, Andry, Fanny, Grados, Aurélie, Ebbo, Mikael, Castela, Emeline, Brihaye, Benoit, Denis, Eric, Liguori, Stéphane, Audemard, Alexandra, Schoindre, Yoland, Morin, Anne-Sophie, Terrier, Benjamin, Marcq, Laurent, Mounier, Nicolas, Lidove, Olivier, Chaborel, Jean-Philippe, and Quinsat, Denis
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- 2019
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3. Cogan syndrome: Characteristics, outcome and treatment in a French nationwide retrospective study and literature review
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Durtette, Charlotte, Hachulla, Eric, Resche-Rigon, Matthieu, Papo, Thomas, Zénone, Thierry, Lioger, Bertrand, Deligny, Christophe, Lambert, Marc, Landron, Cédric, Pouchot, Jacques, Kahn, Jean Emmanuel, Lavigne, Christian, De Wazieres, Benoit, Dhote, Robin, Gondran, Guillaume, Pertuiset, Edouard, Quemeneur, Thomas, Hamidou, Mohamed, Sève, Pascal, Le Gallou, Thomas, Grasland, Anne, Hatron, Pierre-Yves, Fain, Olivier, and Mekinian, Arsène
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- 2017
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4. Central nervous system involvement in eosinophilic granulomatosis with polyangiitis (Churg-Strauss): Report of 26 patients and review of the literature
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André, Raphaël, Cottin, Vincent, Saraux, Jean-Luc, Blaison, Gilles, Bienvenu, Boris, Cathebras, Pascal, Dhote, Robin, Foucher, Aurélie, Gil, Helder, Lapoirie, Joëlle, Launay, David, Loustau, Valentine, Maurier, François, Pertuiset, Edouard, Zénone, Thierry, Seebach, Jörg, Costedoat-Chalumeau, Nathalie, Puéchal, Xavier, Mouthon, Luc, Guillevin, Loïc, and Terrier, Benjamin
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- 2017
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5. Risk of autoimmune diseases and human papilloma virus (HPV) vaccines: Six years of case-referent surveillance
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Abbas, Firas, Abdelmoumni, Abdelhakim, Hilliquin, Pascal, Requeda, Elisabeth, Adoue, Daniel, Brassat, David, Agard, Christian, Masseau, Agathe, Aladjidi, Nathalie, Clet, Johanna, Fernandes, Helder, Lemasson, Gwendal, Perel, Yves, Raymond, Isabelle, Richer, Olivier, Vital, Anne, Allain-Launay, Emma, Bru, Marie, Nicolino, Marc, Thomas, Caroline, Altman, Jean-Jacques, Amsallem, Daniel, Aras, Nazmiye, Boukari, Latifato, Dubrel, Marie, Fain, Olivier, Letellier, Edouard, Lucidarme, Nadine, Mekinian, Arsène, Morin, Anne-Sophie, Stirnemann, Jérôme, Atlan, Catherine, Audry, Dominique, Augustin, Jérôme, Bakir, Redouane, Bartolucci, Pablo, Chevalier, Xavier, Godeau, Bertrand, Guillaud, Constance, Khellaf, Mehdi, Limal, Nicolas, Lousteau, Valentine, Mahevas, Matthieu, Méliksetyan, Gayane, Michel, Marc, Roumier, Mathilde, Bayart, Sophie, Bonnet, Fabrice, Decaux, Olivier, Bekherraz, Amine, Brihaye, Benoit, Dachez, Roger, Daugas, Eric, Hayem, Gilles, Meyer, Olivier, Papo, Thomas, Pasqualoni, Elisa, Sacre, Karim, Travert, Florence, Bellon, Hélène, Beltrand, Jacques, Lefrere, François, Simon, Albane, Benhamou, Pierre-Yves, Benveniste, Olivier, Bolgert, Francis, Costedoat-Chalumeau, Nathalie, De Paz, Raphael, Demeret, Sophie, Fautrel, Bruno, Jacqueminet, Sophie, Louapre, Céline, Maillart, Elizabeth, Morel, Nathalie, Papeix, Caroline, Rigabert, Julie, Bensaid, Philippe, Berger, Claire, Berquin, Patrick, Le Moing, Anne-Gaëlle, Berroir, Stéphane, Besson, Gérard, Boutte, Célia, Casez, Olivier, Bonnotte, Bernard, Audia, Sylvain, Bossu-Estour, Cécile, Bourgarit, Anne, Dupuy, Alain, Keshmandt, Homa, Bourre, Bertrand, Brac, Aude, Perrin, Agnès, Pondarré, Corinne, Villar-Fimbel, Sylvie, Bruckert, Isabelle, Cosson, Anne, Magy-Bertrand, Nadine, Tisserand, Guillaume, Camu, William, Carlander, Bertrand, Morales, Raul Juntas, Cances, Claude, Pasquet, Marlene, Castilla Lievre, Maria Angela, Chabroux, Stephanie, Charif, Mamoud, Chatelus, Emmanuel, Sibilia, Jean, Chevrant-Breton, Jacqueline, Clavel, Sylvaine, Bille-Turc, Françoise, Cohen, Jacques, Courcoux, Marie France, Leverger, Guy, Machet, Laurent, Cuisset, Jean-Marie, Cony-Makhoul, Pascale, Darsy, Paul, Favre, Sandrine, Giraud, Pierrick, Leitenschenck, Laurence, Monteiro, Irène, Morati, Chafika, DeSeze, Jérôme, Dinulescu, Monica, Dhaoui, Taher, Dommange-Romero, Florence, Drevard, Elisabeth, Dupuis, Clémentine, Dumuis, Marie-Laure, Durand, Jean-Marc, Farad, Samia, Lecomte, Pierre, Pierre, Peggy, Fouyssac, Fanny, Gaudin, Philippe, Gautier, Alain, Gellen-Dautremer, Justine, Jarrin, Irène, Richette, Pascal, Georget, Emilie, Gras, Pierre, Moreau, Thibault, Giraud, Eric, Hacini, Maya, Mayer, Anne, Guillaumat, Cécile, Guillaume, Séverine, Guitton, Corinne, Kone-Paut, Isabelle, Marsaud, Céline, Rossi, Linda, Guyot, Marie-Hélène, Hassler, Patrick, Heimfert, Claude, Heinzlef, Olivier, Hillion, Brigitte, Hocquelet, Catherine, Husson, Helene, Ichai, Pierre, Jeziorski, Eric, Deslandre, Chantal Job, Le Guern, Véronique, Kamenov, Kamen, Kerlan, Véronique, Lemoine, Philippe, Misery, Laurent, Pan-Petesch, Brigitte, Krivitzky, Alain, Labauge, Pierre, Rodier, Michel, Lacade, Chadi, Razafimahefa, Berthe, Lachgar, Karim, Larmarau, Marie-Pierre, Leblanc, Thierry, Lebrun-Frenay, Christine, Lefèbvre, Patrick, Lejoyeux, Philippe, Leske, Charles, Ly, Kim, Magy, Laurent, Mansuy, Sylvie, Marechaud, Richard, Martin Negrier, Marie-Laure, Sole, Guilhem, Maupetit, Jean, Mazingue, Françoise, Mochon, Stéphanie, Moktar, Blidi, Morcamp, Donald, Morlet-Barla, Nathalie, Nicolas, Guillaume, Pautot, Vivien, Pellier, Isabelle, Verret, Jean-Luc, Outteryck, Olivier, Vermersch, Patrick, Pallot-Prades, Beatrice, Paquet, Jean Michel, Puechal, Xavier, Sortais, Annie, Pelletier, Jean, Rico, Audrey, Pez, Dominique, Stankoff, Bruno, Quittet, Philippe, Rémy, Claude, Roba, Eléna, Rosario, Hélène, Roudaut, Nathalie, Sonnet, Emmanuel, Ruel, Michel, Sebban, Samuel, Schaepelynck, Pauline, Simonin, Marie-Jeanne, Vial, Christophe, Viallard, Jean-Francois, Ladedan, Isabelle, Zenone, Thierry, Grimaldi-Bensouda, Lamiae, Rossignol, Michel, Koné-Paut, Isabelle, Courcoux, Marie-France, Viallard, Jean-François, Bourgault-Villada, Isabelle, Breart, Gerard, and Abenhaim, Lucien
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- 2017
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6. Update of penetrance estimates in Birt-Hogg-Dubé syndrome
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Bruinsma, Fiona Jane, Dowty, James G., Win, Aung Ko, Goddard, Laura C., Agrawal, Prachi, Attina', Domenico, Bissada, Nabil, De Luise, Monica, Eisen, Daniel B., Furuya, Mitsuko, Gasparre, Giuseppe, Genuardi, Maurizio, Gerdes, Anne Marie, Hansen, Thomas Van Overeem, Houweling, Arjan C., Johannesma, Paul Christiaan, Lencastre, André, Lim, Derek, Lindor, Noralane M., Luzzi, Valentina, Lynch, Maeve, Maffé, Antonella, Menko, Fred H., Michels, Guido, Pulido, Jose S., Ryu, Jay H., Sattler, Elke C., Steinlein, Ortrud K., Tomassetti, Sara, Tucker, Kathy, Turchetti, Daniela, Van De Beek, Irma, Van Riel, Lore, Van Steensel, Maurice, Zenone, Thierry, Zompatori, Maurizo, Walsh, Jennifer, Bondavalli, Davide, Maher, Eamonn R., Winship, Ingrid M., Bruinsma, Fiona Jane, Dowty, James G., Win, Aung Ko, Goddard, Laura C., Agrawal, Prachi, Attina', Domenico, Bissada, Nabil, De Luise, Monica, Eisen, Daniel B., Furuya, Mitsuko, Gasparre, Giuseppe, Genuardi, Maurizio, Gerdes, Anne Marie, Hansen, Thomas Van Overeem, Houweling, Arjan C., Johannesma, Paul Christiaan, Lencastre, André, Lim, Derek, Lindor, Noralane M., Luzzi, Valentina, Lynch, Maeve, Maffé, Antonella, Menko, Fred H., Michels, Guido, Pulido, Jose S., Ryu, Jay H., Sattler, Elke C., Steinlein, Ortrud K., Tomassetti, Sara, Tucker, Kathy, Turchetti, Daniela, Van De Beek, Irma, Van Riel, Lore, Van Steensel, Maurice, Zenone, Thierry, Zompatori, Maurizo, Walsh, Jennifer, Bondavalli, Davide, Maher, Eamonn R., and Winship, Ingrid M.
- Abstract
Background Birt-Hogg-Dubé (BHD) syndrome is a rare genetic syndrome caused by pathogenic or likely pathogenic germline variants in the FLCN gene. Patients with BHD syndrome have an increased risk of fibrofolliculomas, pulmonary cysts, pneumothorax and renal cell carcinoma. There is debate regarding whether colonic polyps should be added to the criteria. Previous risk estimates have mostly been based on small clinical case series. Methods A comprehensive review was conducted to identify studies that had recruited families carrying pathogenic or likely pathogenic variants in FLCN. Pedigree data were requested from these studies and pooled. Segregation analysis was used to estimate the cumulative risk of each manifestation for carriers of FLCN pathogenic variants. Results Our final dataset contained 204 families that were informative for at least one manifestation of BHD (67 families informative for skin manifestations, 63 for lung, 88 for renal carcinoma and 29 for polyps). By age 70 years, male carriers of the FLCN variant have an estimated 19% (95% CI 12% to 31%) risk of renal tumours, 87% (95% CI 80% to 92%) of lung involvement and 87% (95% CI 78% to 93%) of skin lesions, while female carriers had an estimated 21% (95% CI 13% to 32%) risk of renal tumours, 82% (95% CI 73% to 88%) of lung involvement and 78% (95% CI 67% to 85%) of skin lesions. The cumulative risk of colonic polyps by age 70 years old was 21% (95% CI 8% to 45%) for male carriers and 32% (95% CI 16% to 53%) for female carriers. Conclusions These updated penetrance estimates, based on a large number of families, are important for the genetic counselling and clinical management of BHD syndrome.
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- 2023
7. A comparison between nailfold capillaroscopy patterns in adulthood in juvenile and adult-onset systemic sclerosis: A EUSTAR exploratory study
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Airò, Paolo, Alegre-Sancho, Juan Jose, Allanore, Yannick, Ananieva, Lidia P., Ancuta, Codrina, Andrade, Luis Eduardo, Aringer, Martin, Becvar, Radim, Bojinca, Mihai, Butrimiene, Irena, Cantatore, Francesco Paolo, Caporali, Roberto, Caramaschi, Paola, Carreira, Patricia E., Chirieac, Rodica, Corrado, Ada, Cosentino, Vanesa, Cuomo, Giovanna, Czirjak, Laszlo, Da Silva, José Antonio Pereira, la Peña Lefebvre, Paloma García de, De Keyser, Filip, de Souza Müller, Carolina, Damgaard, Kirsten, Damjanov, Nemanja, Denisov, Lev N., Distler, Oliver, Doube, Alan, Dumitrascu, Alina, Engelhart, Merete, Exposito, Marta Valero, Eyerich, Kilian, Farge-Bancel, Dominique, Azevedo, Valderílio Feijó, Foti, Rosario, Frerix, Marc, Gabrielli, Armando, Garen, Torhild, Gottschalk, Paola, Groseanu, Laura, Guiducci, Serena, Günther, Claudia, Hachulla, Eric, Hein, Rüdiger, Heitmann, Stefan, Henes, Jörg, Hesselstrand, Roger, Highton, John, Iannone, Florenzo, Ionescu, Ruxandra Maria, Kayser, Cristiane, Karpec, Diana, Kerzberg, Eduardo, Kotulska, Anna, Kopec-Medrek, Magdalena, Kucharz, Eugene, Krummel-Lorenz, Brigitte, Lauffer, Felix, Launay, David, Li, Mengtao, Litinsky, Ira, Loyo, Esthela, Cerinic, Marco Matucci, Meroni, Pierluigi, Midtvedt, Øyvind, Mihai, Carmen Marina, Montecucco, Carlomaurizio, Montoya, Fabiana, Morgiel, Ewa, Mouthon, Luc, Müller-Ladner, Ulf, Nielsen, Henrik, Opris, Daniela, Ortiz-Santamaria, Vera, Otsa, Kati, Pileckyte, Margarita, Pisarri, Simonetta, Popescu, Monica, Pozzi, Maria Rosa, Puppo, Francesco, Radominski, Sebastião Cezar, Riccieri, Valeria, Rosato, Edoardo, Rozman, Blaz, Rubio, Silvia Rodriguez, Rugiene, Rita, Saar, Petra, Salvador, Maria João, Seidel, Matthias, Sokolik, Renata, Solanki, Kamal, Stamenkovic, Bojana, Stankovic, Aleksandra, Stebbings, Simon, Strauss, Gitte, Sulli, Alberto, Szamosi, Szilvia, Szechinski, Jacek, Szmyrka-Kaczmarek, Magdalena, Szücs, Gabriella, Tanaseanu, Cristina-Mihaela, Tiglea, Isabela, Tyndall, Alan, Ughi, Nicola, Uprus, Maria, Vacca, Alessandra, Varju, Cecilia, Venalis, Algirdas, Venalis, Paulius, Walker, Ulrich A., Widuchowska, Malgorzata, Wiland, Piotr, Wuttge, Dirk M., Zeni, Silvana, Zenone, Thierry, Ingegnoli, Francesca, Boracchi, Patrizia, Gualtierotti, Roberta, Smith, Vanessa, Cutolo, Maurizio, and Foeldvari, Ivan
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- 2015
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8. Predictors of early relapse in patients with non-infectious mixed cryoglobulinemia vasculitis: Results from the French nationwide CryoVas survey
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Terrier, Benjamin, Marie, Isabelle, Launay, David, Lacraz, Adeline, Belenotti, Pauline, de Saint-Martin, Luc, Quemeneur, Thomas, Huart, Antoine, Bonnet, Fabrice, Le Guenno, Guillaume, Kahn, Jean-Emmanuel, Hinschberger, Olivier, Rullier, Patricia, Diot, Elisabeth, Lazaro, Estibaliz, Bridoux, Frank, Zénone, Thierry, Carrat, Fabrice, Hermine, Olivier, Léger, Jean-Marc, Mariette, Xavier, Senet, Patricia, Plaisier, Emmanuelle, and Cacoub, Patrice
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- 2014
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9. Deep characterization of the anti-drug antibodies developed in Fabry disease patients, a prospective analysis from the French multicenter cohort FFABRY
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Mauhin, Wladimir, Lidove, Olivier, Amelin, Damien, Lamari, Foudil, Caillaud, Catherine, Mingozzi, Federico, Dzangué-Tchoupou, Gaëlle, Arouche-Delaperche, Louiza, Douillard, Claire, Dussol, Bertrand, Leguy-Seguin, Vanessa, D’Halluin, Pauline, Noel, Esther, Zenone, Thierry, Matignon, Marie, Maillot, François, Ly, Kim-Heang, Besson, Gérard, Willems, Marjolaine, Labombarda, Fabien, Masseau, Agathe, Lavigne, Christian, Froissart, Roseline, Lacombe, Didier, Ziza, Jean Marc, Hachulla, Eric, and Benveniste, Olivier
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- 2018
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10. Syndrome de Cogan
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Zenone, Thierry
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- 2013
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11. Prediction of improvement in skin fibrosis in diffuse cutaneous systemic sclerosis: a EUSTAR analysis
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Dobrota, Rucsandra, Maurer, Britta, Graf, Nicole, Jordan, Suzana, Mihai, Carina, Kowal-Bielecka, Otylia, Allanore, Yannick, Distler, Oliver, Cerinic, Marco Matucci, Guiducci, Serena, Walker, Ulrich, Lapadula, Giovanni, Iannone, Florenzo, Becvar, Radim, Sierakowsky, Stanislaw, Cutolo, Maurizio, Sulli, Alberto, Valentini, Gabriele, Cuomo, Giovanna, Vettori, Serena, Riemekasten, Gabriela, Siegert, Elise, Rednic, Simona, Nicoara, Ileana, Kahan, André, Vlachoyiannopoulos, P., Montecucco, C., Caporali, Roberto, Carreira, Patricia E., Novak, Srdan, Czirják, László, Varju, Cecilia, Chizzolini, Carlo, Kucharz, Eugene J., Kotulska, Anna, Kopec-Medrek, Magdalena, Widuchowska, Malgorzata, Cozzi, Franco, Rozman, Blaz, Mallia, Carmel, Coleiro, Bernard, Gabrielli, Armando, Farge, Dominique, Wu, Chen, Marjanovic, Zora, Faivre, Helene, Hij, Darin, Dhamadi, Roza, Airò, Paolo, Hesselstrand, Roger, Wollheim, Frank, Wuttge, Dirk M, Andréasson, Kristofer, Martinovic, Duska, Balbir-Gurman, Alexandra, Braun-Moscovici, Yolanda, Trotta, F., Lo Monaco, Andrea, Hunzelmann, Nicolas, Pellerito, Raffaele, Mauriziano, Ospedale, Bambara, Lisa Maria, Caramaschi, Paola, Black, Carol, Denton, Christopher, Damjanov, Nemanja, Henes, Jörg, Ortiz Santamaria, Vera, Heitmann, Stefan, Krasowska, Dorota, Seidel, Matthias, Burkhardt, Harald, Himsel, Andrea, Salvador, Maria J., Silva, José Antonio Pereira Da, Stamenkovic, Bojana, Stankovic, Aleksandra, Banja, Niska, Tikly, Mohammed, Ananieva, Lidia P., Denisov, Lev N., Müller-Ladner, Ulf, Frerix, Marc, Tarner, Ingo, Scorza, Raffaella, Clinica, U.O. Immunologia, Engelhart, Merete, Strauss, Gitte, Nielsen, Henrik, Damgaard, Kirsten, Mendoza, Antonio Zea, de la Puente, Carlos, Giraldo, Walter A. Sifuentes, Midtvedt, Øyvind, Reiseter, Silje, Hachulla, Eric, Launay, David, Valesini, Guido, Riccieri, Valeria, Ionescu, Ruxandra Maria, Opris, Daniela, Groseanu, Laura, Cornateanu, Roxana Sfrent, Ionitescu, Razvan, Gherghe, Ana Maria, Soare, Alina, Gorga, Marilena, Bojinca, Mihai, Schett, Georg, Distler, Jörg HW, Beyer, Christian, Meroni, Pierluigi, Ingegnoli, Francesca, Mouthon, Luc, De Keyser, Filip, Smith, Vanessa, Cantatore, Francesco P., Corrado, Ada, Pozzi, Maria R., Eyerich, Kilian, Hein, Rüdiger, Knott, Elisabeth, Wiland, Piotr, Szmyrka-Kaczmarek, Magdalena, Sokolik, Renata, Morgiel, Ewa, Madej, Marta, Krummel-Lorenz, Brigitte, Aringer, Martin, Günther, Claudia, Westhovens, Rene, de Langhe, Ellen, Lenaerts, Jan, Anic, Branimir, Baresic, Marko, Mayer, Miroslav, Radominski, Sebastião C., de Souza Müller, Carolina, Azevedo, Valderílio F., Agachi, Svetlana, Groppa, Liliana, Chiaburu, Lealea, Russu, Eugen, Popa, Sergei, Zenone, Thierry, Highton, John, Stamp, Lisa, Chapman, Peter, O’Donnell, John, Solanki, Kamal, Veale, Douglas, OʼRourke, Marie, Loyo, Esthela, Li, Mengtao, Rosato, Edoardo, Amoroso, Antonio, Tanaseanu, Cristina-Mihaela, Popescu, Monica, Dumitrascu, Alina, Tiglea, Isabela, Foti, Rosario, Chirieac, Rodica, Ancuta, Codrina, Villiger, Peter, Adler, Sabine, Sibilia, Jean, Chatelus, Emmanuel, Gottenberg, Jacques Eric, Chifflot, Hélène, Litinsky, Ira, Venalis, Algirdas, Butrimiene, Irena, Venalis, Paulius, Rugiene, Rita, Karpec, Diana, Saketkoo, Lesley Ann, Lasky, Joseph A., Kerzberg, Eduardo, Montoya, Fabiana, Cosentino, Vanesa, Limonta, Massimiliano, Brucato, Antonio Luca, Lupi, Elide, Spertini, François, Ribi, Camillo, Buss, Guillaume, Pasquali, Jean Louis, Martin, Thierry, and Gorse, Audrey
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- 2016
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12. Mapping and predicting mortality from systemic sclerosis
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Elhai, Muriel, Meune, Christophe, Boubaya, Marouane, Avouac, Jérôme, Hachulla, Eric, Balbir-Gurman, Alexandra, Riemekasten, Gabriela, Airò, Paolo, Joven, Beatriz, Vettori, Serena, Cozzi, Franco, Ullman, Susanne, Czirják, László, Tikly, Mohammed, Müller-Ladner, Ulf, Caramaschi, Paola, Distler, Oliver, Iannone, Florenzo, Ananieva, Lidia P, Hesselstrand, Roger, Becvar, Radim, Gabrielli, Armando, Damjanov, Nemanja, Salvador, Maria J, Riccieri, Valeria, Mihai, Carina, Szücs, Gabriella, Walker, Ulrich A, Hunzelmann, Nicolas, Martinovic, Duska, Smith, Vanessa, Müller, Carolina de Souza, Montecucco, Carlo Maurizio, Opris, Daniela, Ingegnoli, Francesca, Vlachoyiannopoulos, Panayiotis G, Stamenkovic, Bojana, Rosato, Edoardo, Heitmann, Stefan, Distler, Jörg H W, Zenone, Thierry, Seidel, Matthias, Vacca, Alessandra, Langhe, Ellen De, Novak, Srdan, Cutolo, Maurizio, Mouthon, Luc, Henes, Jörg, Chizzolini, Carlo, Mühlen, Carlos Alberto von, Solanki, Kamal, Rednic, Simona, Stamp, Lisa, Anic, Branimir, Santamaria, Vera Ortiz, Santis, Maria De, Yavuz, Sule, Sifuentes-Giraldo, Walter Alberto, Chatelus, Emmanuel, Stork, Jiri, Laar, Jacob van, Loyo, Esthela, García de la Peña Lefebvre, Paloma, Eyerich, Kilian, Cosentino, Vanesa, Alegre-Sancho, Juan Jose, Kowal-Bielecka, Otylia, Rey, Grégoire, Matucci-Cerinic, Marco, and Allanore, Yannick
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- 2017
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13. Management of noninfectious mixed cryoglobulinemia vasculitis: data from 242 cases included in the CryoVas survey
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Terrier, Benjamin, Krastinova, Evguenia, Marie, Isabelle, Launay, David, Lacraz, Adeline, Belenotti, Pauline, de Saint-Martin, Luc, Quemeneur, Thomas, Huart, Antoine, Bonnet, Fabrice, Le Guenno, Guillaume, Kahn, Jean-Emmanuel, Hinschberger, Olivier, Rullier, Patricia, Diot, Elisabeth, Lazaro, Estibaliz, Bridoux, Frank, Zénone, Thierry, Carrat, Fabrice, Hermine, Olivier, Léger, Jean-Marc, Mariette, Xavier, Senet, Patricia, Plaisier, Emmanuelle, and Cacoub, Patrice
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- 2012
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14. Pericardial effusion and giant cell arteritis
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Zenone, Thierry and Puget, Marie
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- 2014
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15. Cardiac device implantation in Fabry disease: A retrospective monocentric study
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Sené, Thomas, Lidove, Olivier, Sebbah, Joel, Darondel, Jean-Marc, Picard, Hervé, Aaron, Laurent, Fain, Olivier, Zenone, Thierry, Joly, Dominique, Charron, Philippe, and Ziza, Jean-Marc
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- 2016
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16. Digital ulcers predict a worse disease course in patients with systemic sclerosis
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Mihai, Carina, Landewé, Robert, van der Heijde, Désirée, Walker, Ulrich A, Constantin, Paul I, Gherghe, Ana Maria, Ionescu, Ruxandra, Rednic, Simona, Allanore, Yannick, Avouac, Jérôme, Czirják, László, Hachulla, Eric, Riemekasten, Gabriela, Cozzi, Franco, Airò, Paolo, Cutolo, Maurizio, Mueller-Ladner, Ulf, Matucci-Cerinic, Marco, Launay, David, Dobrotă, Rucsandra, Sfrenţ-Cornăţeanu, Roxana, Zingarelli, Stefania, Pigatto, Erika, Cuomo, Giovanna, Caramaschi, Paola, Ananieva, Lidia, Ullman, Susanne, Iversen, Line, Gurman, Alexandra Balbir, Braun-Moscovici, Yolanda, Carreira, Patricia E., Joven, Beatriz E, Minier, Tünde, Guiducci, Serena, Bellando-Randone, Silvia, Pellerito, Raffaele, Hunzelmann, Nicolas, Tarner, Ingo H., Radominski, Sebastião Cezar, de Souza Müller, Carolina, Iannone, Florenzo, Henes, Jörg, Bancel, Dominique Farge, Damjanov, Nemanja, Ostojić, Predrag, Pozzi, Maria Rosa, Hesselstrand, Roger, Denton, Christopher, Krasowska, Dorota, Tikly, Mohammed, Riccieri, Valeria, Cantatore, Francesco Paolo, Corrado, Ada, Da Silva, José Antonio Pereira, Salvador, Maria João, Tyndall, Alan, Gabrielli, Armando, Distler, Oliver, Jordan, Suzan, Heitmann, Stefan, Burkhardt, Harald, Himsel, Andrea, Rozman, Blaz, Smith, Vanessa, De Keyser, Filip, Kalitena, Dusanka Martinovic, Radic, Mislav, Filipescu, Ileana, Petcu, Ana, Vlachoyiannopoulos, Panayiotis, Kucharz, Eugene J., Widuchowska, Malgorzata, Kopec-Medrek, Magdalena, Kotulska, Anna, Szücs, Gabriella, Stankovic, Aleksandra, Stamenkovic, Bojana, Selmi, Carlo Francesco, De Santis, Maria, Marasini, Bianca, Coleiro, Bernard, Santamaria, Vera Ortiz, Westhovens, René, Bečvář, Radim, Novak, Srdan, Engelhart, Merete, Meroni, Pierluigi, Ingegnoli, Francesca, Zeni, Silvana, Sulli, Alberto, Distler, Jörg, Yavuz, Sule, Montecucco, Carlomaurizio, Eyerich, Kilian, Krummel-Lorenz, Brigitte, Zenone, Thierry, Midtvedt, Øyvind, Chizzolini, Carlo, Seidel, Matthias, Oleszowsky, Mara, Üprus, Maria, Opriş, Daniela, Groşeanu, Laura, Bielecka, Otylia Kowal, Antonio, Zea Mendoza, Szechinski, Jacek, Morović-Vergles, Jadranka, Scorza, Raffaella, Puppo, Francesco, Mathieu, Alessandro, Anic, Branimir, Stork, Jiri, Stebbings, Simon, Inanc, Murat, Hasler, Paul, von Mühlen, Carlos Alberto, Aringer, Martin, Popa, Sergei, Li, Mengtao, and Rosato, Edoardo
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- 2016
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17. A gender gap in primary and secondary heart dysfunctions in systemic sclerosis: a EUSTAR prospective study
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Elhai, Muriel, Avouac, Jérôme, Walker, Ulrich A, Matucci-Cerinic, Marco, Riemekasten, Gabriela, Airò, Paolo, Hachulla, Eric, Valentini, Gabriele, Carreira, Patricia E, Cozzi, Franco, Balbir Gurman, Alexandra, Braun-Moscovici, Yolanda, Damjanov, Nemanja, Ananieva, Lidia P, Scorza, Raffaella, Jimenez, Sergio, Busquets, Joanna, Li, Mengtao, Müller-Ladner, Ulf, Kahan, André, Distler, Oliver, Allanore, Yannick, Guiducci, Serena, Tyndall, Alan, Lapadula, Giovanni, Iannone, Florenzo, Becvar, Radim, Sierakowsky, Stanislaw, Bielecka, Otylia Kowal, Cutolo, Maurizio, Sulli, Alberto, Cuomo, Giovanna, Vettori, Serena, Rednic, Simona, Nicoara, Ileana, Vlachoyiannopoulos, P., Montecucco, C., Caporali, Roberto, Novak, Srdan, Czirják, László, Varju, Cecilia, Chizzolini, Carlo, Kucharz, Eugene J., Kotulska, Anna, Kopec-Medrek, Magdalena, Widuchowska, Malgorzata, Rozman, Blaz, Mallia, Carmel, Coleiro, Bernard, Gabrielli, Armando, Farge, Dominique, Hij, Adrian, Hesselstrand, Roger, Scheja, Agneta, Wollheim, Frank, Martinovic, Duska, Govoni, M., Monaco, Andrea Lo, Hunzelmann, Nicolas, Pellerito, Raffaele, Bambara, Lisa Maria, Caramaschi, Paola, Black, Carol, Denton, Christopher, Henes, Jörg, Santamaria, Vera Ortiz, Heitmann, Stefan, Krasowska, Dorota, Seidel, Matthias, Oleszowsky, Mara, Burkhardt, Harald, Himsel, Andrea, Salvador, Maria J., Stamenkovic, Bojana, Stankovic, Aleksandra, Tikly, Mohammed, Starovoytova, Maya N., Engelhart, Merete, Strauss, Gitte, Nielsen, Henrik, Damgaard, Kirsten, Szücs, Gabriella, Zea Mendoza, Antonio, de la Puente Buijdos, Carlos, Sifuentes Giraldo, Walter A., Midtvedt, Øyvind, Garen, Torhild, Launay, David, Valesini, Guido, Riccieri, Valeria, Ionescu, Ruxandra Maria, Opris, Daniela, Groseanu, Laura, Wigley, Fredrick M., Mihai, Carmen M., Cornateanu, Roxana Sfrent, Ionitescu, Razvan, Gherghe, Ana Maria, Gorga, Marilena, Dobrota, Rucsandra, Bojinca, Mihai, Schett, Georg, Distler, Jörg HW, Meroni, Pierluigi, Zeni, Silvana, Mouthon, Luc, Keyser, Filip De, Smith, Vanessa, Cantatore, Francesco P., Corrado, Ada, Ullman, Susanne, Iversen, Line, Pozzi, Maria R., Eyerich, Kilian, Hein, Rüdiger, Knott, Elisabeth, Szechinski, Jacek, Wiland, Piotr, Szmyrka-Kaczmarek, Magdalena, Sokolik, Renata, Morgiel, Ewa, Krummel-Lorenz, Brigitte, Saar, Petra, Aringer, Martin, Günther, Claudia, Anic, Branimir, Baresic, Marko, Mayer, Miroslav, Radominski, Sebastião C., Müller, Carolina de Souza, Azevedo, Valderílio F., Agachi, Svetlana, Groppa, Liliana, Chiaburu, Lealea, Russu, Eugen, Zenone, Thierry, Stebbings, Simon, Highton, John, Stamp, Lisa, Chapman, Peter, Baron, Murray, OʼDonnell, John, Solanki, Kamal, Doube, Alan, Veale, Douglas, OʼRourke, Marie, Loyo, Esthela, Rosato, Edoardo, Pisarri, Simonetta, Tanaseanu, Cristina-Mihaela, Popescu, Monica, Dumitrascu, Alina, Tiglea, Isabela, Chirieac, Rodica, Ancuta, Codrina, Furst, Daniel E., Kafaja, Suzanne, Lefebvre, Paloma García de la Peña, Rubio, Silvia Rodriguez, Exposito, Marta Valero, Sibilia, Jean, Chatelus, Emmanuel, Gottenberg, Jacques Eric, Chifflot, Hélène, Litinsky, Ira, Venalis, Algirdas, Butrimiene, Irena, Venalis, Paulius, Rugiene, Rita, Karpec, Diana, Kerzberg, Eduardo, Montoya, Fabiana, and Cosentino, Vanesa
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- 2016
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18. Joint and tendon involvement predict disease progression in systemic sclerosis: a EUSTAR prospective study
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Avouac, Jérôme, Walker, Ulrich A, Hachulla, Eric, Riemekasten, Gabriela, Cuomo, Giovanna, Carreira, Patricia E, Caramaschi, Paola, Ananieva, Lidia P, Matucci-Cerinic, Marco, Czirjak, Laszlo, Denton, Christopher, Ladner, Ulf Müller, Allanore, Yannick, Guiducci, Serena, Tyndall, Alan, Lapadula, Giovanni, Iannone, Florenzo, Distler, Oliver, Becvar, Radim, Sierakowsky, Stanislaw, Bielecka, Otylia Kowal, Cutolo, Maurizio, Sulli, Alberto, Valentini, Gabriele, Vlachoyiannopoulos, Panayiotis G., Montecucco, Carlomaurizio, Caporali, Roberto, Novak, Srdan, Chizzolini, Carlo, Kucharz, Eugene J., Kotulska, Anna, Cozzi, Franco, Rozman, Blaz, Mallia, Carmel, Coleiro, Bernard, Gabrielli, Armando, Farge-Bancel, Dominique, Hadj-Khelifa, Sondess, Airò, Paolo, Hesselstrand, Roger, Scheja, Agneta, Martinovic, Duska, Gurman, Alexandra Balbir, Braun-Moscovici, Yolanda, Hunzelmann, Nicolas, Pellerito, Raffaele, Bambara, Lisa Maria, Morovic-Vergles, Jadranka, Black, Carol, Damjanov, Nemanja, Kötter, Ina, Santamaria, Vera Ortiz, Heitmann, Stefan, Krasowska, Dorota, Seidel, Matthias, Hasler, Paul, Burkhardt, Harald, Himsel, Andrea, Silva, José Antonio Pereira Da, Salvador, Maria João, Stamenkovi, Bojana, Stankovic, Aleksandra, Marasini, Bianca, Belloli, Laura, Tikly, Mohammed, Denisov, Lev N., Scorza, Raffaella, Engelhart, Merete, Strauss, Gitte, Szücs, Gabriella, Szamosi, Szilvia, de la Puente, Carlos, de la Pena Lefebvre, Paloma García, Midtvedt, Øyvind, Garen, Torhild, Launay, David, Valesini, Guido, Riccieri, Valeria, Ionescu, Ruxandra Maria, Opris, Daniela, Wigley, Fredrick M., Stoica, Viktor, Mihai, Carmen Marina, Distler, Jörg, Meroni, Pierluigi, Zeni, Silvana, Mouthon, Luc, Smith, Vanessa, Cantatore, Francesco Paolo, Corrado, Ada, Ullman, Susanne, Iversen, Line, Pozzi, Maria Rosa, Eyerich, Kilian, Hein, Rüdiger, Szechinski, Jacek, Wiland, Piotr, Krummel-Lorenz, Brigitte, Aringer, Martin, Westhovens, Rene, De Langhe, Ellen, Anic, Branimir, Baresi, Marko, Üprus, Maria, Otsa, Kati, Yavuz, Sule, Radominski, Sebastião Cezar, de Souza Müller, Carolina, Jimenez, Sergio, Busquets, Joanna, Popa, Sergei, Agachi, Svetlana, Zenone, Thierry, Mathieu, Alessandro, Vacca, Alessandra, Stamp, Lisa, Chapman, Peter, Tanaseanu, Cristina-Mihaela, Popescu, Monica, Foti, Rosario, and Rubio, Silvia Rodriguez
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- 2016
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19. Presentation and Real-World Management of Giant Cell Arteritis (Artemis Study)
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Mahr, Alfred, primary, Hachulla, Eric, additional, de Boysson, Hubert, additional, Guerroui, Nassim, additional, Héron, Emmanuel, additional, Vinzio, Stéphane, additional, Broner, Jonathan, additional, Lapébie, François-Xavier, additional, Michaud, Martin, additional, Sailler, Laurent, additional, Zenone, Thierry, additional, Djerad, Mohamed, additional, Jouvray, Mathieu, additional, Shipley, Emilie, additional, Tieulie, Nathalie, additional, Armengol, Guillaume, additional, Bouldoires, Bastien, additional, Viallard, Jean-Francois, additional, Idier, Isabelle, additional, Paccalin, Marc, additional, and Devauchelle-Pensec, Valérie, additional
- Published
- 2021
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20. Prediction of worsening of skin fibrosis in patients with diffuse cutaneous systemic sclerosis using the EUSTAR database
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Maurer, Britta, Graf, Nicole, Michel, Beat A, Müller-Ladner, Ulf, Czirják, László, Denton, Christopher P, Tyndall, Alan, Metzig, Carola, Lanius, Vivian, Khanna, Dinesh, Distler, Oliver, Tarner, Ingo H, Cerinic, Marco Matucci, Guiducci, Serena, Walker, Ulrich, Lapadula, Giovanni, Iannone, Florenzo, Becvar, Radim, Sierakowsky, Stanislaw, Bielecka, Otylia Kowal, Cutolo, Maurizio, Sulli, Alberto, Valentini, Gabriele, Cuomo, Giovanna, Vettori, Serena, Riemekasten, Gabriele, Rednic, Simona, Nicoara, Ileana, Kahan, André, Allanore, Yannick, Vlachoyiannopoulos, P, Montecucco, C, Caporali, Roberto, Carreira, Patricia E, Novak, Srdan, Varju, Cecilia, Chizzolini, Carlo, Kucharz, Eugene J, Kotulska, Anna, Kopec-Medrek, Magdalena, Widuchowska, Malgorzata, Cozzi, Franco, Rozman, Blaz, Mallia, Carmel, Coleiro, Bernard, Gabrielli, Armando, Farge, Dominique, Hij, Adrian, Airò, Paolo, Hesselstrand, Roger, Scheja, Agneta, Wollheim, Frank, Martinovic, Duska, Gurman, Alexandra Balbir, Braun-Moscovici, Yolanda, Govoni, M, Monaco, Andrea Lo, Hunzelmann, Nicolas, Pellerito, Raffaele, Bambara, Lisa Maria, Caramaschi, Paola, Black, Carol, Damjanov, Nemanja, Santamaria, Vera Ortiz, Heitmann, Stefan, Krasowska, Dorota, Seidel, Matthias, Oleszowsky, Mara, Burkhardt, Harald, Himsel, Andrea, Salvador, Maria J, Stamenkovic, Bojana, Stankovic, Aleksandra, Tikly, Mohammed, Starovoytova, Maya N, Ananieva, Lidia P, Scorza, Raffaella, Engelhart, Merete, Strauss, Gitte, Nielsen, Henrik, Damgaard, Kirsten, Szücs, Gabriella, Mendoza, Antonio Zea, Buijdos, Carlos de la Puente, Sifuentes Giraldo, Walter A., Midtvedt, Øyvind, Garen, Torhild, Hachulla, Eric, Launay, David, Valesini, Guido, Riccieri, Valeria, Ionescu, Ruxandra Maria, Opris, Daniela, Groseanu, Laura, Wigley, Fredrick M, Mihai, Carmen M, Cornateanu, Roxana Sfrent, Ionitescu, Razvan, Gherghe, Ana Maria, Gorga, Marilena, Dobrota, Rucsandra, Bojinca, Mihai, Schett, Georg, Distler, Jörg HW, Meroni, Pierluigi, Zeni, Silvana, Mouthon, Luc, Keyser, Filip De, Cantatore, Francesco P, Corrado, Ada, Ullman, Susanne, Iversen, Line, Pozzi, Maria R, Eyerich, Kilian, Hein, Rüdiger, Knott, Elisabeth, Szechinski, Jacek, Wiland, Piotr, Szmyrka-Kaczmarek, Magdalena, Sokolik, Renata, Morgiel, Ewa, Krummel-Lorenz, Brigitte, Saar, Petra, Aringer, Martin, Günther, Claudia, Anic, Branimir, Baresic, Marko, Mayer, Miroslav, Radominski, Sebastião C, Müller, Carolina de Souza, Azevedo, Valderílio F, Agachi, Svetlana, Groppa, Liliana, Chiaburu, Lealea, Russu, Eugen, Zenone, Thierry, Highton, John, Stamp, Lisa, Chapman, Peter, OʼDonnell, John, Solanki, Kamal, Doube, Alan, Veale, Douglas, O’Rourke, Marie, Loyo, Esthela, Li, Mengtao, Rosato, Edoardo, Pisarri, Simonetta, Tanaseanu, Cristina-Mihaela, Popescu, Monica, Dumitrascu, Alina, Tiglea, Isabela, Chirieac, Rodica, Ancuta, Codrina, E Furst, Daniel, Kafaja, Suzanne, Lefebvre, Paloma García de la Peña, Rubio, Silvia Rodriguez, Exposito, Marta Valero, Sibilia, Jean, Chatelus, Emmanuel, Gottenberg, Jacques Eric, Chifflot, Hélène, Litinsky, Ira, Venalis, Algirdas, Butrimiene, Irena, Venalis, Paulius, Rugiene, Rita, Karpec, Diana, Kerzberg, Eduardo, Montoya, Fabiana, and Cosentino, Vanesa
- Published
- 2015
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21. Effects and safety of rituximab in systemic sclerosis: an analysis from the European Scleroderma Trial and Research (EUSTAR) group
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Jordan, Suzana, Distler, Jörg H W, Maurer, Britta, Huscher, Dörte, van Laar, Jacob M, Allanore, Yannick, Distler, Oliver, Airo, Paolo, Sancho, Juan José Alegre, Ananjeva, Lidia, Ancuta, Codrina Michaela, Aringer, Martin, Balbir-Gurman, Alexandra, Cantatore, Francesco Paolo, Caramaschi, Paola, Chatelus, Emmanuel, Codullo, Veronica, Farge-Bancel, Dominique, Foti, Rosario, Gabrielli, Armando, Henes, Jörg, Herrgott, Ilka, Iannone, Florenzo, Ingegnoli, Francesca, Loyo, Esthela, Matucci-Cerinić, Marco, Abdel Atty Mohamed, Walid Ahmed, Müller-Ladner, Ulf, Palm, Øyvind, Popa, Sergiu, Riemekasten, Gabriela, Rednic, Simona, Rosato, Edoardo, Saracco, Marta, Scheja, Agneta, Smith, Vanessa, Mihai, Carina, Szucs, Gabriela, Tomšič, Matija, Valentini, Gabriele, Walker, Ulrich A, Westhovens, Rene, Yavuz, Sule Kurhan, and Zenone, Thierry
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- 2015
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22. Ectopic Tumoral Calcinosis in Systemic Sclerosis
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Zenone, Thierry and Couret, Marie
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- 2015
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23. The Clinical Spectrum and Therapeutic Management of Hypocomplementemic Urticarial Vasculitis: Data From a French Nationwide Study of Fifty-Seven Patients
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Jachiet, Marie, Flageul, Béatrice, Deroux, Alban, Le Quellec, Alain, Maurier, François, Cordoliani, Florence, Godmer, Pascal, Abasq, Claire, Astudillo, Leonardo, Belenotti, Pauline, Bessis, Didier, Bigot, Adrien, Doutre, Marie-Sylvie, Ebbo, Mikaël, Guichard, Isabelle, Hachulla, Eric, Héron, Emmanuel, Jeudy, Géraldine, Jourde-Chiche, Noémie, Jullien, Denis, Lavigne, Christian, Machet, Laurent, Macher, Marie-Alice, Martel, Clotilde, Melboucy-Belkhir, Sara, Morice, Cécile, Petit, Antoine, Simorre, Bernard, Zenone, Thierry, Bouillet, Laurence, Bagot, Martine, Frémeaux-Bacchi, Véronique, Guillevin, Loïc, Mouthon, Luc, Dupin, Nicolas, Aractingi, Selim, and Terrier, Benjamin
- Published
- 2015
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24. Characteristics of cerebrovascular accidents at time of diagnosis in a series of 98 patients with giant cell arteritis
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Zenone, Thierry and Puget, Marie
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- 2013
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25. Camptocormia as a clinical manifestation of polymyositis/systemic sclerosis overlap myositis associated with anti-Ku
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Zenone, Thierry, Streichenberger, Nathalie, and Puget, Marie
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- 2013
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26. Dry cough is a frequent manifestation of giant cell arteritis
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Zenone, Thierry and Puget, Marie
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- 2013
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27. Parotid gland non-Hodgkin lymphoma in primary Sjögren syndrome
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Zenone, Thierry
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- 2012
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28. Systematic retrospective study of 64 patients with anti-Mi2 dermatomyositis: A classic skin rash with a necrotizing myositis and high risk of malignancy
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Monseau, Grégoire, Landon-Cardinal, Océane, Stenzel, Werner, Schoindre, Yoland, Mariampillai, Kubéraka, Barete, Stéphane, Martel, Clothilde, Masseau, Agathe, Meyer, Alain, Terrier, Benjamin, Guégan, Sarah, Verneuil, Laurence, Audia, Sylvain, Livideanu, Cristian Bulai, Hachulla, Eric, Kahn, Jean-Emmanuel, Lefevre, Guillaume, Maurier, François, Moulis, Guillaume, Papo, Thomas, Dossier, Antoine, Descamps, Vincent, Salort-Campana, Emmanuelle, Richard, Marie-Aleth, Bergot, Emmanuel, Mortier, Laurent, Costedoat-Chalumeau, Nathalie, Genot, Séverine, Perez, Florian, Piette, Anne-Marie, Samson, Maxime, Schleinitz, Nicolas, Zénone, Thierry, Lacoste, Marie, de Boysson, Hubert, Madaule, Serge, Rigolet, Aude, Champtiaux, Nicolas, Hervier, Baptiste, Bouvier, Anne-Marie, Jooste, Valérie, Léonard-Louis, Sarah, Maisonobe, Thierry, Aouba, Achille, Benveniste, Olivier, Bienvenu, Boris, and Allenbach, Yves
- Published
- 2020
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29. Chronic obstructive pulmonary disease associated with hypocomplementemic urticarial vasculitis
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David, Clémence, Jachiet, Marie, Pineton de Chambrun, Marc, Gamez, Anne Sophie, Mehdaoui, Anas, Zenone, Thierry, Gobert, Delphine, Aouba, Achille, Peterschmitt, Anne, Palat, Sylvain, Lifermann, François, Blockmans, Daniel, Feuillet-Soummer, Séverine, Mouthon, Luc, and Terrier, Benjamin
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- 2020
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30. Orbital myositis and Crohnʼs disease
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Zenone, Thierry
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- 2014
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31. Fever of Unknown Origin in Rheumatic Diseases
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Zenone, Thierry
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- 2007
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32. Sensitivity of clinically abnormal temporal artery in giant cell arteritis
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Zenone, Thierry and Puget, Marie
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- 2013
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33. Flare of essential mixed cryoglobulinemic vasculitis with hemorrhagic bullous purpura after rituximab infusion
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Zenone, Thierry
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- 2013
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34. Prognostic factors of survival in patients with non-infectious mixed cryoglobulinaemia vasculitis: data from 242 cases included in the CryoVas survey
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Terrier, Benjamin, Carrat, Fabrice, Krastinova, Evguenia, Marie, Isabelle, Launay, David, Lacraz, Adeline, Belenotti, Pauline, de Saint Martin, Luc, Quemeneur, Thomas, Huart, Antoine, Bonnet, Fabrice, Le Guenno, Guillaume, Kahn, Jean-Emmanuel, Hinschberger, Olivier, Rullier, Patricia, Hummel, Aurelie, Diot, Elisabeth, Pagnoux, Christian, Lzaro, Estibaliz, Bridoux, Frank, Zenone, Thierry, Hermine, Olivier, Leger, Jean-Marc, Mariette, Xavier, Senet, Patricia, Plaisier, Emmanuelle, Cacoub, Patrice, Laurent, Aaron, Sébastien, Abad, Redouane, Bakir, Pauline, Belenotti, Lucas, Benarous, Nathalie, Beneton, Gilles, Blaison, Claire, Blanchard-Delaunay, Fabrice, Bonnet, Frank, Bridoux, Patrice, Cacoub, Pascal, Cathébras, Fabrice, Carrat, Laurent, Chiche, Olivier, Chosidow, Bernard, Combe, Christian, Combe, Nathalie, Costedoat-Chalumeau, Pierre, Cougoul, Bernard, Cribier, Gilles, Defuentes, Elisabeth, Diot, Isabelle, Durieu, Philippe, Evon, Thibault, Fraisse, Camille, Francès, Hélène, Francois, Thierry, Frouget, Loik, Geffray, Helder, Gil, Jean, Gutnecht, Eric, Hachulla, Olivier, Hermine, Olivier, Hinschberger, Arnaud, Hot, Antoine, Huart, Aurélie, Hummel, Jean-Emmanuel, Kahn, Gilles, Kaplanski, Alexandre, Karras, Evguenia, Krastinova, Adeline, Lacraz, Claire, Larroche, David, Launay, Estibaliz, Lazaro, Guillaume, Le Guenno, Véronique, Leblond, Jean-Marc, Léger, Nicolas, Limal, Eric, Liozon, Catherine, Lok, Véronique, Loustau-Ratti, Kim, Ly, Hervé, Maillard, Raifah, Makdassi, Isabelle, Marie, Xavier, Mariette, Olivier, Meyer, Catherine, Michel, Philippe, Modiano, David, Noel, Raphaele, Nove-Josserand, Céline, Onno, Christian, Pagnoux, Caroline, Pajot, Géraldine, Perceau, Antoinette, Perlat, Anne-Marie, Piette, Emmanuelle, Plaisier, Jean-François, Pouget-Abadie, Thomas, Quemeneur, Viviane, Queyrel, Joseph, Rivalan, Eric, Rondeau, Patricia, Rullier, Luc, de Saint-Martin, Elisabeth, Salles-Thomasson, Françoise, Sarrot-Reynauld, Thierry, Schaeverbeke, Gwendoline, Sebille, Patricia, Senet, Raphaele, Seror, Jacques, Serratrice, Alexandre, Somogyi, Pascale, Soria, Benjamin, Terrier, Marie-Francoise, Thiercelin-Legrand, François, Truchetet, Jean-Paul, Vagneur, Philippe, Vanhille, Bérengère, Vivet, Pierre-Jean, Weiller, Bernadette, Woehl-Kremer, Jean-Marie, Woehl, and Thierry, Zénone
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- 2013
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35. Cornea verticillata and acroparesthesia efficiently discriminate clusters of severity in Fabry disease
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Mauhin, Wladimir, primary, Benveniste, Olivier, additional, Amelin, Damien, additional, Montagner, Clémence, additional, Lamari, Foudil, additional, Caillaud, Catherine, additional, Douillard, Claire, additional, Dussol, Bertrand, additional, Leguy-Seguin, Vanessa, additional, D'Halluin, Pauline, additional, Noel, Esther, additional, Zenone, Thierry, additional, Matignon, Marie, additional, Maillot, François, additional, Ly, Kim-Heang, additional, Besson, Gérard, additional, Willems, Marjolaine, additional, Labombarda, Fabien, additional, Masseau, Agathe, additional, Lavigne, Christian, additional, Lacombe, Didier, additional, Maillard, Hélène, additional, and Lidove, Olivier, additional
- Published
- 2020
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36. Predictors of disease worsening defined by progression of organ damage in diffuse systemic sclerosis: A European Scleroderma Trials and Research (EUSTAR) analysis
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Becker, Mike, Graf, Nicole, Sauter, Rafael, Allanore, Yannick, Curram, John, Denton, Christopher P., Khanna, Dinesh, Matucci-Cerinic, Marco, Pena, Janethe de Oliveira, Pope, Janet E., Distler, Oliver, Guiducci, Serena, Walker, Ulrich, Jaeger, Veronika, Bannert, Bettina, Lapadula, Giovanni, Becvarare, Radim, Cutolo, Maurizio, Valentini, Gabriele, Siegert, Elise, Rednic, Simona, Montecucco, C., Carreira, Patricia E., Novak, Srdan, Czirjak, Laszlo, Varju, Cecilia, Chizzolini, Carlo, Allai, Daniela, Kucharz, Eugene J., Cozzi, Franco, Rozman, Blaz, Mallia, Carmel, Gabrielli, Armando, Bancel, Dominique Farge, Airo, Paolo, Hesselstrand, Roger, Martinovic, Duska, Balbir-Gurman, Alexandra, Braun-Moscovici, Yolanda, Hunzelmann, Nicolas, Pellerito, Raffaele, Caramaschi, Paola, Black, Carol, Damjanov, Nemanja, Henes, Joerg, Ortiz Santamaria, Vera, Heitmann, Stefan, Seidel, Matthias, Pereira Da Silva, Jose Antonio, Stamenkovic, Bojana, Selmi, Carlo Francesco, Tikly, Mohammed, Denisov, Lev N., Mueller-Ladner, Ulf, Engelhart, Merete, Hachulla, Eric, Riccieri, Valeria, Ionescu, Ruxandra Maria, Mihai, Carina, Sunderkoetter, Cord, Kuhn, Annegret, Schett, Georg, Distler, Joerg, Meroni, Pierluigi, Ingegnoli, Francesca, Mouthon, Luc, De Keyser, Filip, Smith, Vanessa, Cantatore, Francesco Paolo, Corrado, Ada, Ullman, Susanne, Iversen, Line, Pozzi, Maria Rosa, Eyerich, Kilian, Hein, Ruediger, Knott, Elisabeth, Wiland, Piotr, Szmyrka-Kaczmarek, Magdalena, Sokolik, Renata, Morgiel, Ewa, Madej, Marta, Jose Alegre-Sancho, Juan, Krummel-Lorenz, Brigitte, Saar, Petra, Aringer, Martin, Guenther, Claudia, Anne, Erler, Westhovens, Rene, De langhe, Ellen, Lenaerts, Jan, Anic, Branimir, Baresic, Marko, Mayer, Miroslav, Uprus, Maria, Otsa, Kati, Yavuz, Sule, Radominski, Sebastiao Cezar, Mueller, Carolina de Souza, Azevedo, Valderilio Feijo, Popa, Sergei, Zenone, Thierry, Stebbings, Simon, Highton, John, Mathieu, Alessandro, Vacca, Alessandra, Stamp, Lisa, Chapman, Peter, O'Donnell, John, Solanki, Kamal, Doube, Alan, Veale, Douglas, O'Rourke, Marie, Loyo, Esthela, Li, Mengtao, Rosato, Edoardo, Amoroso, Antonio, Gigante, Antonietta, Oksel, Fahrettin, Yargucu, Figen, Tanaseanu, Cristina-Mihaela, Popescu, Monica, Dumitrascu, Alina, Tiglea, Isabela, Foti, Rosario, Visalli, Elisa, Benenati, Alessia, Amato, Giorgio, Ancuta, Codrina, Chirieac, Rodica, Villiger, Peter, Adler, Sabine, Dan, Diana, de la Pena Lefebvre, Paloma Garcia, Rodriguez Rubio, Silvia, Valero Exposito, Marta, Sibilia, Jean, Chatelus, Emmanuel, Gottenberg, Jacques Eric, Chifflot, Helene, Litinsky, Ira, Del Galdo, Francesco, Venalis, Algirdas, Saketkoo, Lesley Ann, Lasky, Joseph A., Kerzberg, Eduardo, Montoya, Fabiana, Cosentino, Vanesa, Limonta, Massimiliano, Brucato, Antonio Luca, Lupi, Elide, Spertini, Francois, Ribi, Camillo, Buss, Guillaume, Martin, Thierry, Guffroy, Aurelien, Poindron, Vincent, Chung, Lori, Schmeiser, Tim, Zebryk, Pawel, Riso, Nuno, Riemekasten, Gabriela, Rezus, Elena, Puttini, Piercarlo Sarzi, Ege Üniversitesi, University of Zurich, Distler, Oliver, Chizzolini, Carlo, Allai, Daniela, Becker, M., Graf, N., Sauter, R., Allanore, Y., Curram, J., Denton, C. P., Khanna, D., Matucci-Cerinic, M., de Oliveira Pena, J., Pope, J. E., Distler, O., Guiducci, S., Walker, U., Jaeger, V., Bannert, B., Lapadula, G., Becvarare, R., Cutolo, M., Valentini, G., Siegert, E., Rednic, S., Montecucco, C., Carreira, P. E., Novak, S., Czirjak, L., Varju, C., Chizzolini, C., Allai, D., Kucharz, E. J., Cozzi, F., Rozman, B., Mallia, C., Gabrielli, A., Bancel, D. F., Airo, P., Hesselstrand, R., Martinovic, D., Balbir-Gurman, A., Braun-Moscovici, Y., Hunzelmann, N., Pellerito, R., Caramaschi, P., Black, C., Damjanov, N., Henes, J., Santamaria, V. O., Heitmann, S., Seidel, M., Pereira Da Silva, J. A., Stamenkovic, B., Selmi, C. F., Tikly, M., Denisov, L. N., Muller-Ladner, U., Engelhart, M., Hachulla, E., Riccieri, V., Ionescu, R. M., Mihai, C., Sunderkotter, C., Kuhn, A., Schett, G., Distler, J., Meroni, P., Ingegnoli, F., Mouthon, L., De Keyser, F., Smith, V., Cantatore, F. P., Corrado, A., Ullman, S., Iversen, L., Pozzi, M. R., Eyerich, K., Hein, R., Knott, E., Wiland, P., Szmyrka-Kaczmarek, M., Sokolik, R., Morgiel, E., Madej, M., Alegre-Sancho, J. J., Krummel-Lorenz, B., Saar, P., Aringer, M., Gunther, C., Anne, E., Westhovens, R., De Langhe, E., Lenaerts, J., Anic, B., Baresic, M., Mayer, M., Uprus, M., Otsa, K., Yavuz, S., Radominski, S. C., de Souza Muller, C., Azevedo, V. F., Popa, S., Zenone, T., Stebbings, S., Highton, J., Mathieu, A., Vacca, A., Stamp, L., Chapman, P., O'Donnell, J., Solanki, K., Doube, A., Veale, D., O'Rourke, M., Loyo, E., Li, M., Rosato, E., Amoroso, A., Gigante, A., Oksel, F., Yargucu, F., Tanaseanu, C. -M., Popescu, M., Dumitrascu, A., Tiglea, I., Foti, R., Visalli, E., Benenati, A., Amato, G., Ancuta, C., Chirieac, R., Villiger, P., Adler, S., Dan, D., de la Pena Lefebvre, P. G., Rubio, S. R., Exposito, M. V., Sibilia, J., Chatelus, E., Gottenberg, J. E., Chifflot, H., Litinsky, I., Del Galdo, F., Venalis, A., Saketkoo, L. A., Lasky, J. A., Kerzberg, E., Montoya, F., Cosentino, V., Limonta, M., Brucato, A. L., Lupi, E., Spertini, F., Ribi, C., Buss, G., Martin, T., Guffroy, A., Poindron, V., Chung, L., Schmeiser, T., Zebryk, P., Riso, N., Riemekasten, G., Rezus, E., and Sarzi Puttini, P.
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INVOLVEMENT ,SELECTION ,BIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences ,diffuse ,predictive factors ,systemic sclerosis ,2745 Rheumatology ,epidemiologic methods ,morbidity ,Disease ,Immunology ,General Biochemistry, Genetics and Molecular Biology ,Immunology and Allergy ,Rheumatology ,INTERSTITIAL LUNG-DISEASE ,disease worsening, mortality, predictive factors, systemic sclerosis ,predictive factor ,disease worsening ,DESIGN ,middle aged ,Medicine and Health Sciences ,FIBROSIS ,scleroderma ,SKIN THICKNESS SCORE ,mortality ,skin and connective tissue diseases ,Prospective cohort study ,humans ,lung diseases ,ddc:616 ,education.field_of_study ,heart diseases ,integumentary system ,clinical trials as topic ,BIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti ,10051 Rheumatology Clinic and Institute of Physical Medicine ,Interstitial lung disease ,follow-up studies ,ddc ,female ,Cohort ,2723 Immunology and Allergy ,europe ,Life Sciences & Biomedicine ,CLINICAL-TRIALS ,survival rate ,medicine.medical_specialty ,Population ,610 Medicine & health ,disease progression ,male ,1300 General Biochemistry, Genetics and Molecular Biology ,Internal medicine ,Severity of illness ,REGRESSION ,medicine ,severity of illness index ,education ,Survival rate ,METAANALYSIS ,2403 Immunology ,Science & Technology ,Scleroderma, Systemic ,business.industry ,MORTALITY ,systemic ,medicine.disease ,prospective studies ,Clinical trial ,prognosis ,scleroderma, diffuse ,scleroderma, systemic ,Scleroderma, Diffuse ,business - Abstract
PubMed: 31227488, Objectives Mortality and worsening of organ function are desirable endpoints for clinical trials in systemic sclerosis (SSc). The aim of this study was to identify factors that allow enrichment of patients with these endpoints, in a population of patients from the European Scleroderma Trials and Research group database. Methods Inclusion criteria were diagnosis of diffuse SSc and follow-up over 12±3 months. Disease worsening/organ progression was fulfilled if any of the following events occurred: new renal crisis; decrease of lung or heart function; new echocardiography-suspected pulmonary hypertension or death. In total, 42 clinical parameters were chosen as predictors for the analysis by using (1) imputation of missing data on the basis of multivariate imputation and (2) least absolute shrinkage and selection operator regression. Results Of 1451 patients meeting the inclusion criteria, 706 had complete data on outcome parameters and were included in the analysis. Of the 42 outcome predictors, eight remained in the final regression model. There was substantial evidence for a strong association between disease progression and age, active digital ulcer (DU), lung fibrosis, muscle weakness and elevated C-reactive protein (CRP) level. Active DU, CRP elevation, lung fibrosis and muscle weakness were also associated with a significantly shorter time to disease progression. A bootstrap validation step with 10 000 repetitions successfully validated the model. Conclusions The use of the predictive factors presented here could enable cohort enrichment with patients at risk for overall disease worsening in SSc clinical trials. © Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY. Published by BMJ., Bayer Bayer, United Kingdom Université Paris Descartes Li Ka Shing Foundation, LKSF University of Michigan, U-M, 1Department of Rheumatology and the Centre of experimental Rheumatology, University Hospital Zurich, Zurich, switzerland 2Graf Biostatistics, Winterthur, switzerland 3Big Data institute, li Ka shing Centre for Health information and Discovery, nuffield Department of Medicine, University of Oxford, Oxford, UK 4Rheumatology a Department, Paris Descartes University, sorbonne Paris Cité, Cochin Hospital, Paris, France 5Data science and analytics, Bayer plc, Reading, UK 6UCl Division of Medicine, Royal Free Campus, london, UK 7Division of Rheumatology, Department of internal Medicine, University of Michigan scleroderma Program, University of Michigan, ann arbor, Michigan, Usa 8Department of experimental and Clinical Medicine, University of Florence, Florence, italy 9Bayer Us llC, Whippany, new Jersey, Usa 10Department of Medicine, Division of Rheumatology, University of Western Ontario, st. Joseph’s Health Care, london, Ontario, Canada Acknowledgements The R-code for the linear Mi-lassO was received from Qixuan Chen.21 Medical writing assistance was provided by adelphi Communications ltd (Bollington, UK), funded by Bayer aG (Berlin, Germany)., Contributors study conception and design, acquisition of data, analysis and interpretation of data and drafting and revising the article: OD and MB; analysis and interpretation of data: OD, MB, Rs and nG. all authors have critically reviewed and approved the final submitted version to be published. Funding This study was supported by a grant from Bayer aG. Bayer employees are coauthors of this paper and supported the study design and interpretation of the data, but otherwise Bayer had no influence on the study., Competing interests MOB declares no conflict of interest. OD has had consultancy relationships with actelion, Bayer, Biogen idec, Boehringer ingelheim, Chemomab, espeRare foundation, Genentech/Roche, GsK, inventiva, italfarmaco, lilly, medac, Medimmune, Mitsubishi Tanabe Pharma, Pharmacyclics, novartis, Pfizer, sanofi, sinoxa and UCB in the area of potential treatments of scleroderma and its complications. OD has received research funding from actelion, Bayer, Boehringer ingelheim, Mitsubishi Tanabe Pharma and Roche in the area of potential treatments of scleroderma and its complications. OD has a patent for mir-29 licensed for the treatment of systemic sclerosis. DK has consultancy relationships and/or has received grant/research support from Bayer, Bristol-Myers squibb, Boehringer ingelheim, Genentech/Roche, niH, Pfizer, sanofi-aventis Pharmaceuticals, actelion Pharmaceuticals Us, Chemomab, Corbus, Covis, Cytori, eicos, eMD serono, Gilead, GlaxosmithKline, and UCB Pharma. He is a shareholder of eicos. CPD has consultancy relationships with and/or has received speakers’ bureau fees from actelion Pharmaceuticals Us, Bayer aG, GlaxosmithKline, Csl Behring, Merck serono, Roche Pharmaceuticals, Genentech and Biogen iDeC inc., inventiva, sanofi-aventis Pharmaceuticals and Boehringer ingelheim. JeP has consultancy relationships with and/or has received grant/research support from actelion, Bayer aG, Bristol-Myers squibb, Merck, Pfizer inc. and Roche. MM-C has consultancy relationships and/ or has received grant/research support from Pfizer, Bristol-Myers squibb, actelion, UCB Pharma, Bayer, Chemomab, Genentech/Roche, inventiva and lilly. Ya has consultancy relationships with and/or has received grant/research support from actelion, Pharmaceuticals Us, Bayer aG, Bristol-Myers squibb, inventiva, Medac, Pfizer inc., Roche Pharmaceuticals, Genentech and Biogen iDeC inc., sanofi-aventis Pharmaceuticals and servier. JdOP and JC are employees of Bayer. nTG has nothing to disclose.
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- 2019
37. Progressive skin fibrosis is associated with a decline in lung function and worse survival in patients with diffuse cutaneous systemic sclerosis in the european scleroderma trials and research (eustar) cohort
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Wu, Wanlong, Jordan, Suzana, Graf, Nicole, Pena, Janethe de Oliveira, Curram, John, Allanore, Yannick, Matucci-Cerinic, Marco, Pope, Janet E., Denton, Christopher P., Khanna, Dinesh, Distler, Oliver, Guiducci, Serena, Walker, Ulrich, Jaeger, Veronika, Bannert, Bettina, Lapadula, Giovanni, Becvarare, Radim, Cutolo, Maurizio, Valentini, Gabriele, Siegert, Elise, Rednic, Simona, Montecucco, C., Carreira, Patricia E., Novak, Srdan, Czirjak, Laszlo, Varju, Cecilia, Chizzolini, Carlo, Allai, Daniela, Kucharz, Eugene J., Cozzi, Franco, Rozman, Blaz, Mallia, Carmel, Gabrielli, Armando, Bancel, Dominique Farge, Airo, Paolo, Hesselstrand, Roger, Martinovic, Duska, Balbir-Gurman, Alexandra, Braun-Moscovici, Yolanda, Hunzelmann, Nicolas, Pellerito, Raffaele, Caramaschi, Paola, Black, Carol, Damjanov, Nemanja, Henes, Joerg, Ortiz Santamaria, Vera, Heitmann, Stefan, Seidel, Matthias, Pereira Da Silva, Jose Antonio, Stamenkovic, Bojana, Selmi, Carlo Francesco, Tikly, Mohammed, Denisov, Lev N., Mueller-Ladner, Ulf, Engelhart, Merete, Hachulla, Eric, Riccieri, Valeria, Ionescu, Ruxandra Maria, Mihai, Carina, Sunderkoetter, Cord, Kuhn, Annegret, Schett, Georg, Distler, Joerg, Meroni, Pierluigi, Ingegnoli, Francesca, Mouthon, Luc, De Keyser, Filip, Smith, Vanessa, Cantatore, Francesco Paolo, Corrado, Ada, Ullman, Susanne, Iversen, Line, Pozzi, Maria Rosa, Eyerich, Kilian, Hein, Ruediger, Knott, Elisabeth, Wiland, Piotr, Szmyrka-Kaczmarek, Magdalena, Sokolik, Renata, Morgiel, Ewa, Madej, Marta, Jose Alegre-Sancho, Juan, Krummel-Lorenz, Brigitte, Saar, Petra, Aringer, Martin, Guenther, Claudia, Anne, Erler, Westhovens, Rene, De Langhe, Ellen, Lenaerts, Jan, Anic, Branimir, Baresic, Marko, Mayer, Miroslav, Uprus, Maria, Otsa, Kati, Yavuz, Sule, Radominski, Sebastiao Cezar, Mueller, Carolina de Souza, Azevedo, Valderilio Feijo, Popa, Sergei, Zenone, Thierry, Stebbings, Simon, Highton, John, Mathieu, Alessandro, Vacca, Alessandra, Stamp, Lisa, Chapman, Peter, O'Donnell, John, Solanki, Kamal, Doube, Alan, Veale, Douglas, O'Rourke, Marie, Loyo, Esthela, Li, Mengtao, Rosato, Edoardo, Amoroso, Antonio, Gigante, Antonietta, Oksel, Fahrettin, Yargucu, Figen, Tanaseanu, Cristina-Mihaela, Popescu, Monica, Dumitrascu, Alina, Tiglea, Isabela, Foti, Rosario, Visalli, Elisa, Benenati, Alessia, Amato, Giorgio, Ancuta, Codrina, Chirieac, Rodica, Villiger, Peter, Adler, Sabine, Dan, Diana, de la Pena Lefebvre, Paloma Garcia, Rodriguez Rubio, Silvia, Valero Exposito, Marta, Sibilia, Jean, Chatelus, Emmanuel, Gottenberg, Jacques Eric, Chifflot, Helene, Litinsky, Ira, Del Galdo, Francesco, Venalis, Algirdas, Saketkoo, Lesley Ann, Lasky, Joseph A., Kerzberg, Eduardo, Montoya, Fabiana, Cosentino, Vanesa, Limonta, Massimiliano, Brucato, Antonio Luca, Lupi, Elide, Spertini, Francois, Ribi, Camillo, Buss, Guillaume, Martin, Thierry, Guffroy, Aurelien, Poindron, Vincent, Chung, Lori, Schmeiser, Tim, Zebryk, Pawel, Riso, Nuno, Riemekasten, Gabriela, Rezus, Elena, Puttini, Piercarlo Sarzi, Wu, W., Jordan, S., Graf, N., de Oliveira Pena, J., Curram, J., Allanore, Y., Matucci-Cerinic, M., Pope, J. E., Denton, C. P., Khanna, D., Distler, O., Guiducci, S., Walker, U., Jaeger, V., Bannert, B., Lapadula, G., Becvarare, R., Cutolo, M., Valentini, G., Siegert, E., Rednic, S., Montecucco, C., Carreira, P. E., Novak, S., Czirjak, L., Varju, C., Chizzolini, C., Allai, D., Kucharz, E. J., Cozzi, F., Rozman, B., Mallia, C., Gabrielli, A., Bancel, D. F., Airo, P., Hesselstrand, R., Martinovic, D., Balbir-Gurman, A., Braun-Moscovici, Y., Hunzelmann, N., Pellerito, R., Caramaschi, P., Black, C., Damjanov, N., Henes, J., Santamaria, V. O., Heitmann, S., Seidel, M., Pereira Da Silva, J. A., Stamenkovic, B., Selmi, C. F., Tikly, M., Denisov, L. N., Muller-Ladner, U., Engelhart, M., Hachulla, E., Riccieri, V., Ionescu, R. M., Mihai, C., Sunderkotter, C., Kuhn, A., Schett, G., Distler, J., Meroni, P., Ingegnoli, F., Mouthon, L., De Keyser, F., Smith, V., Cantatore, F. P., Corrado, A., Ullman, S., Iversen, L., Pozzi, M. R., Eyerich, K., Hein, R., Knott, E., Wiland, P., Szmyrka-Kaczmarek, M., Sokolik, R., Morgiel, E., Madej, M., Alegre-Sancho, J. J., Krummel-Lorenz, B., Saar, P., Aringer, M., Gunther, C., Anne, E., Westhovens, R., De Langhe, E., Lenaerts, J., Anic, B., Baresic, M., Mayer, M., Uprus, M., Otsa, K., Yavuz, S., Radominski, S. C., de Souza Muller, C., Azevedo, V. F., Popa, S., Zenone, T., Stebbings, S., Highton, J., Mathieu, A., Vacca, A., Stamp, L., Chapman, P., O'Donnell, J., Solanki, K., Doube, A., Veale, D., O'Rourke, M., Loyo, E., Li, M., Rosato, E., Amoroso, A., Gigante, A., Oksel, F., Yargucu, F., Tanaseanu, C. -M., Popescu, M., Dumitrascu, A., Tiglea, I., Foti, R., Visalli, E., Benenati, A., Amato, G., Ancuta, C., Chirieac, R., Villiger, P., Adler, S., Dan, D., de la Pena Lefebvre, P. G., Rubio, S. R., Exposito, M. V., Sibilia, J., Chatelus, E., Gottenberg, J. E., Chifflot, H., Litinsky, I., Del Galdo, F., Venalis, A., Saketkoo, L. A., Lasky, J. A., Kerzberg, E., Montoya, F., Cosentino, V., Limonta, M., Brucato, A. L., Lupi, E., Spertini, F., Ribi, C., Buss, G., Martin, T., Guffroy, A., Poindron, V., Chung, L., Schmeiser, T., Zebryk, P., Riso, N., Riemekasten, G., Rezus, E., Sarzi Puttini, P., Ege Üniversitesi, Chizzolini, Carlo, Allali, Danièle, University of Zurich, and Distler, Oliver
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INVOLVEMENT ,Male ,BIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences ,diffuse ,Time Factors ,Databases, Factual ,Skin Diseases/etiology/mortality/physiopathology ,PREDICTION ,Fibrosi ,2745 Rheumatology ,Diffuse/complications/mortality/pathology ,Immunology ,General Biochemistry, Genetics and Molecular Biology ,Immunology and Allergy ,Rheumatology ,Kaplan-Meier Estimate ,ddc:616.07 ,Severity of Illness Index ,Scleroderma ,Cohort Studies ,PROGNOSTIC-FACTORS ,Fibrosis ,Medicine and Health Sciences ,scleroderma ,Lung ,Skin ,integumentary system ,progressive skin fibrosis ,Lung function decline ,BIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti ,10051 Rheumatology Clinic and Institute of Physical Medicine ,DEATH ,Middle Aged ,ddc ,Europe ,VARIABILITY ,factual ,Cohort ,Visceral organ progression ,2723 Immunology and Allergy ,Disease Progression ,Female ,Survival Analysi ,Life Sciences & Biomedicine ,Cohort study ,Human ,Adult ,Skin/pathology ,medicine.medical_specialty ,databases ,All-cause death ,risk analysis ,diffuse cutaneous systemic sclerosis ,610 Medicine & health ,IMPROVEMENT ,Systemic Sclerosis ,Skin Diseases ,THICKNESS SCORE ,VALIDATION ,Databases ,FEV1/FVC ratio ,1300 General Biochemistry, Genetics and Molecular Biology ,Internal medicine ,medicine ,Humans ,Factual ,Survival analysis ,2403 Immunology ,Science & Technology ,Proportional hazards model ,business.industry ,Surrogate endpoint ,MORTALITY ,Skin Disease ,fibrosis ,Progressive skin fibrosi ,Lung/physiopathology ,biomarkers ,Diffuse cutaneous systemic sclerosi ,medicine.disease ,Survival Analysis ,all-cause death ,lung function decline ,visceral organ progression ,adult ,cohort studies ,databases, factual ,disease progression ,female ,humans ,Scleroderma, Diffuse ,Cohort Studie ,business - Abstract
PubMed: 30852552, Objectives To determine whether progressive skin fibrosis is associated with visceral organ progression and mortality during follow-up in patients with diffuse cutaneous systemic sclerosis (dcSSc). Methods We evaluated patients from the European Scleroderma Trials and Research database with dcSSc, baseline modified Rodnan skin score (mRSS) ?7, valid mRSS at 12±3 months after baseline and ?1 annual follow-up visit. Progressive skin fibrosis was defined as an increase in mRSS >5 and ?25% from baseline to 12±3 months. Outcomes were pulmonary, cardiovascular and renal progression, and all-cause death. Associations between skin progression and outcomes were evaluated by Kaplan-Meier survival analysis and multivariable Cox regression. Results Of 1021 included patients, 78 (7.6%) had progressive skin fibrosis (skin progressors). Median follow-up was 3.4 years. Survival analyses indicated that skin progressors had a significantly higher probability of FVC decline ?10% (53.6% vs 34.4%; p, Bayer Bayer, 1Department of Rheumatology, University Hospital Zurich, Zurich, switzerland 2Graf Biostatistics, Winterthur, switzerland 3Clinical Development Pulmonology, Bayer Us llC, Whippany, new Jersey, Usa 4Data science and analytics, Bayer plc, Reading, UK 5Rheumatology a Department, Paris Descartes University, inseRM U1016, sorbonne, Paris Cité, Cochin Hospital, Paris, France 6Division of Rheumatology, University of Florence, Florence, italy 7Department of Medicine, Division of Rheumatology, University of Western Ontario, st. Joseph’s Health Care, london, Western Ontario, Canada 8Department of Rheumatology, Royal Free Hospital, University College london, london, UK 9scleroderma Program, Department of internal Medicine, Division of Rheumatology, University of Michigan, ann arbor, Michigan, Usa Acknowledgements The authors thank nicole schneider for excellent administration and data entry into the eUsTaR cohort. Medical writing assistance was provided by adelphi Communications ltd (Bollington, UK), funded by Bayer aG (Berlin, Germany)., This study was supported by a grant from Bayer aG.
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- 2019
38. Phenotypes determined by cluster analysis and their survival in the prospective European Scleroderma Trials and Research cohort of patients with systemic sclerosis
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Sobanski, Vincent, Giovannelli, Jonathan, Allanore, Yannick, Riemekasten, Gabriela, Airo, Paolo, Vettori, Serena, Cozzi, Franco, Distler, Oliver, Matucci-Cerinic, Marco, Denton, Christopher, Launay, David, Hachulla, Eric, Cerinic, Marco Matucci, Guiducci, Serena, Walker, Ulrich, Kyburz, Diego, Lapadula, Giovanni, Iannone, Florenzo, Maurer, Britta, Jordan, Suzana, Becvar, Radim, Sierakowsky, Stanislaw, Bielecka, Otylia Kowal, Cutolo, Maurizio, Sulli, Alberto, Valentini, Gabriele, Cuomo, Giovanna, Siegert, Elise, Rednic, Simona, Nicoara, Ileana, Kahan, Andre, Vlachoyiannopoulos, Panayiotis, Montecucco, Carlo, Caporali, Roberto, Stork, Jiri, Inanc, Murat, Carreira, Patricia E, Novak, Srdan, Czirjak, Laszlo, Varju, Cecilia, Chizzolini, Carlo, Kucharz, Eugene J, Kotulska, Anna, Kopec-Medrek, Magdalena, Widuchowska, Malgorzata, Rozman, Blaz, Mallia, Carmel, Coleiro, Bernard, Gabrielli, Armando, Farge, Dominique, Wu, Chen, Marjanovic, Zora, Faivre, Helene, Hij, Darin, Dhamadi, Roza, Hesselstrand, Roger, Wollheim, Frank, Wuttge, Dirk M, Andreasson, Kristofer, Martinovic, Duska, Balbir-Gurman, Alexandra, Braun-Moscovici, Yolanda, Trotta, Francesco, Lo Monaco, Andrea, Hunzelmann, Nicolas, Pellerito, Raffaele, Bambara, Lisa Maria, Caramaschi, Paola, Morovic-Vergles, Jadranka, Black, Carol, Damjanov, Nemanja, Henes, Joerg, Ortiz Santamaria, Vera, Heitmann, Stefan, Krasowska, Dorota, Seidel, Matthias, Hasler, Paul, Burkhardt, Harald, Himsel, Andrea, Bajocchi, Gianluigi, Nuova, Arcispedale Santa Maria, Salvador, Maria Joao, Pereira Da Silva, Jose Antonio, Stamenkovic, Bojana, Stankovic, Aleksandra, Selmi, Carlo Francesco, De Santis, Maria, Marasini, Bianca, Tikly, Mohammed, Ananieva, Lidia P, Denisov, Lev N, Mueller-Ladner, Ulf, Frerix, Marc, Tarner, Ingo, Scorza, Raffaella, Puppo, Francesco, Engelhart, Merete, Strauss, Gitte, Nielsen, Henrik, Damgaard, Kirsten, Szucs, Gabriella, Szamosi, Szilvia, Zea Mendoza, Antonio, de la Puente, Carlos, Sifuentes Giraldo, Walter Alberto, Midtvedt, Oyvind, Reiseter, Silje, Garen, Torhild, Valesini, Guido, Riccieri, Valeria, Ionescu, Ruxandra Maria, Opris, Daniela, Groseanu, Laura, Wigley, Fredrick M, Cornateanu, Roxana Sfrent, Ionitescu, Razvan, Gherghe, Ana Maria, Soare, Alina, Gorga, Marilena, Bojinca, Mihai, Mihai, Carina, Milicescu, Mihaela, Sunderkoetter, Cord, Kuhn, Annegret, Sandorfi, Nora, Schett, Georg, Distler, Joerg HW, Beyer, Christian, Meroni, Pierluigi, Ingegnoli, Francesca, Mouthon, Luc, De Keyser, Filip, Smith, Vanessa, Cantatore, Francesco Paolo, Corrado, Ada, Ullman, Susanne, Iversen, Line, von Muehlen, Carlos Alberto, Bohn, Jussara Marilu, Lonzetti, Lilian Scussel, Pozzi, Maria Rosa, Eyerich, Kilian, Hein, Ruediger, Knott, Elisabeth, Wiland, Piotr, Szmyrka-Kaczmarek, Magdalena, Sokolik, Renata, Morgiel, Ewa, Madej, Marta, Houssiau, Frederic A, Jose Alegre-Sancho, Juan, Krummel-Lorenz, Brigitte, Saar, Petra, Aringer, Martin, Guenther, Claudia, Westhovens, Rene, de Langhe, Ellen, Lenaerts, Jan, Anic, Branimir, Baresic, Marko, Mayer, Miroslav, Uprus, Maria, Otsa, Kati, Yavuz, Sule, Granel, Brigitte, Radominski, Sebastiao Cezar, Mueller, Carolina de Souza, Azevedo, Valderilio Feijo, Jimenez, Sergio, Busquets, Joanna, Agachi, Svetlana, Groppa, Liliana, Chiaburu, Lealea, Russu, Eugen, Popa, Sergei, Zenone, Thierry, Pileckyte, Margarita, Stebbings, Simon, Highton, John, Mathieu, Alessandro, Vacca, Alessandra, Sampaio-Barros, Percival D, Yoshinari, Natalino H, Marangoni, Roberta G, Martin, Patricia, Fuocco, Luiza, Stamp, Lisa, Chapman, Peter, O'Donnell, John, Solanki, Kamal, Doube, Alan, Veale, Douglas, O'Rourke, Marie, Loyo, Esthela, Li, Mengtao, Mohamed, Walid Ahmed Abdel Atty, Rosato, Edoardo, Amoroso, Antonio, Gigante, Antonietta, Oksel, Fahrettin, Yargucu, Figen, Tanaseanu, Cristina-Mihaela, Popescu, Monica, Dumitrascu, Alina, Tiglea, Isabela, Foti, Rosario, Chirieac, Rodica, Ancuta, Codrina, Furst, Daniel E, Villiger, Peter, Adler, Sabine, van Laar, Jacob, Kayser, Cristiane, Eduardo, Andrade Luis C, Fathi, Nihal, Hassanien, Manal, de la Pena Lefebvre, Paloma Garcia, Rodriguez Rubio, Silvia, Valero Exposito, Marta, Sibilia, Jean, Chatelus, Emmanuel, Gottenberg, Jacques Eric, Chifflot, Helene, Litinsky, Ira, Emery, Paul, Buch, Maya, Del Galdo, Francesco, Venalis, Algirdas, Butrimiene, Irena, Venalis, Paulius, Rugiene, Rita, Karpec, Diana, Saketkoo, Lesley Ann, Lasky, Joseph A, Kerzberg, Eduardo, Montoya, Fabiana, Cosentino, Vanesa, Limonta, Massimiliano, Brucato, Antonio Luca, Lupi, Elide, Rosner, Itzhak, Rozenbaum, Michael, Slobodin, Gleb, Boulman, Nina, Rimar, Doron, Couto, Maura, Spertini, Francois, Ribi, Camillo, Buss, Guillaume, Kahl, Sarah, Hsu, Vivien M, Chen, Fei, McCloskey, Deborah, Malveaux, Halina, Pasquali, Jean Louis, Martin, Thierry, Gorse, Audrey, Guffroy, Aurelien, Poindron, Vincent, EUSTAR Collaborators, Guiducci, S., Walker, U., Kyburz, D., Lapadula, G., Iannone, F., Maurer, B., Jordan, S., Becvar, R., Sierakowsky, S., Kowal Bielecka, O., Cutolo, M., Sulli, A., Valentini, G., Cuomo, G., Siegert, E., Rednic, S., Nicoara, I., Kahan, A., Vlachoyiannopoulos, P., Montecucco, C., Caporali, R., Stork, J., Inanc, M., Carreira, P.E., Novak, S., Czirják, L., Varju, C., Chizzolini, C., Kucharz, E.J., Kotulska, A., Kopec-Medrek, M., Widuchowska, M., Rozman, B., Mallia, C., Coleiro, B., Gabrielli, A., Farge, D., Wu, C., Marjanovic, Z., Faivre, H., Hij, D., Dhamadi, R., Airò, P., Hesselstrand, R., Wollheim, F., Wuttge, D.M., Andréasson, K., Martinovic, D., Balbir-Gurman, A., Braun-Moscovici, Y., Trotta, F., Lo Monaco, A., Hunzelmann, N., Pellerito, R., Mauriziano, O., Maria Bambara, L., Caramaschi, P., Morovic-Vergles, J., Black, C., Damjanov, N., Henes, J., Ortiz Santamaria, V., Heitmann, S., Krasowska, D., Seidel, M., Hasler, P., Burkhardt, H., Himsel, A., Bajocchi, G., Maria Nuova, A.S., João Salvador, M., Pereira Da Silva, J.A., Stamenkovic, B., Stankovic, A., Francesco Selmi, C., De Santis, M., Marasini, B., Tikly, M., Ananieva, L.P., Denisov, L.N., Müller-Ladner, U., Frerix, M., Tarner, I., Scorza, R., Puppo, F., Engelhart, M., Strauss, G., Nielsen, H., Damgaard, K., Szücs, G., Szamosi, S., Zea Mendoza, A., de la Puente, C., Sifuentes Giraldo, W.A., Midtvedt, Ø., Reiseter, S., Garen, T., Valesini, G., Riccieri, V., Maria Ionescu, R., Opris, D., Groseanu, L., Wigley, F.M., Sfrent Cornateanu, R., Ionitescu, R., Maria Gherghe, A., Soare, A., Gorga, M., Bojinca, M., Mihai, C., Milicescu, M., Sunderkötter, C., Kuhn, A., Sandorfi, N., Schett, G., Distler, J.H., Beyer, C., Meroni, P., Ingegnoli, F., Mouthon, L., De Keyser, F., Smith, V., Paolo Cantatore, F., Corrado, A., Ullman, S., Iversen, L., Alberto von Mühlen, C., Marilu Bohn, J., Scussel Lonzetti, L., Rosa Pozzi, M., Eyerich, K., Hein, R., Knott, E., Wiland, P., Szmyrka-Kaczmarek, M., Sokolik, R., Morgiel, E., Madej, M., Houssiau, F.A., Jose Alegre-Sancho, J., Krummel-Lorenz, B., Saar, P., Aringer, M., Günther, C., Westhovens, R., de Langhe, E., Lenaerts, J., Anic, B., Baresic, M., Mayer, M., Üprus, M., Otsa, K., Yavuz, S., Granel, B., Cezar Radominski, S., de Souza Müller, C., Azevedo, V.F., Jimenez, S., Busquets, J., Agachi, S., Groppa, L., Chiaburu, L., Russu, E., Popa, S., Zenone, T., Pileckyte, M., Stebbings, S., Highton, J., Mathieu, A., Vacca, A., Sampaio-Barros, P.D., Yoshinari, N.H., Marangoni, R.G., Martin, P., Fuocco, L., Stamp, L., Chapman, P., O'Donnell, J., Solanki, K., Doube, A., Veale, D., O'Rourke, M., Loyo, E., Li, M., Abdel Atty Mohamed, W.A., Rosato, E., Amoroso, A., Gigante, A., Oksel, F., Yargucu, F., Tanaseanu, C.M., Popescu, M., Dumitrascu, A., Tiglea, I., Foti, R., Chirieac, R., Ancuta, C., Furst, D.E., Villiger, P., Adler, S., van Laar, J., Kayser, C., Eduardo C, A.L., Fathi, N., Hassanien, M., de la Peña Lefebvre, P.G., Rodriguez Rubio, S., Valero Exposito, M., Sibilia, J., Chatelus, E., Gottenberg, J.E., Chifflot, H., Litinsky, I., Emery, P., Buch, M., Del Galdo, F., Venalis, A., Butrimiene, I., Venalis, P., Rugiene, R., Karpec, D., Ann Saketkoo, L., Lasky, J.A., Kerzberg, E., Montoya, F., Cosentino, V., Limonta, M., Luca Brucato, A., Lupi, E., Rosner, I., Rozenbaum, M., Slobodin, G., Boulman, N., Rimar, D., Couto, M., Spertini, F., Ribi, C., Buss, G., Kahl, S., Hsu, V.M., Chen, F., McCloskey, D., Malveaux, H., Louis Pasquali, J., Martin, T., Gorse, A., Guffroy, A., Poindron, V., and Chizzolini, Carlo
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0301 basic medicine ,Male ,BIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences ,Databases, Factual ,systemic sclerosis ,SUBSETS ,Disease ,Severity of Illness Index ,Scleroderma ,DISEASE ,0302 clinical medicine ,Medicine and Health Sciences ,Immunology and Allergy ,Cluster Analysis ,CRITERIA ,Prospective Studies ,Prospective cohort study ,skin and connective tissue diseases ,integumentary system ,BIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti ,Adult ,Aged ,Autoantibodies/blood ,Europe/epidemiology ,Female ,Humans ,Middle Aged ,Phenotype ,Prognosis ,Scleroderma, Diffuse/blood ,Scleroderma, Diffuse/epidemiology ,Scleroderma, Diffuse/pathology ,Scleroderma, Limited/blood ,Scleroderma, Limited/epidemiology ,Scleroderma, Limited/pathology ,Scleroderma, Systemic/blood ,Scleroderma, Systemic/epidemiology ,Scleroderma, Systemic/pathology ,Connective tissue disease ,ddc ,Europe ,MANIFESTATIONS ,Cohort ,Life Sciences & Biomedicine ,medicine.medical_specialty ,Immunology ,PROFILE ,CLASSIFICATION ,03 medical and health sciences ,Rheumatology ,Scleroderma, Limited ,Internal medicine ,Severity of illness ,medicine ,Autoantibodies ,030203 arthritis & rheumatology ,Science & Technology ,Scleroderma, Systemic ,business.industry ,Autoantibody ,Systemic sclerosis (SSc) ,medicine.disease ,030104 developmental biology ,Scleroderma, Diffuse ,business - Abstract
OBJECTIVE: Systemic sclerosis (SSc) is a heterogeneous connective tissue disease that is typically subdivided into limited cutaneous SSc (lcSSc) and diffuse cutaneous SSc (dcSSc) depending on the extent of skin involvement. This subclassification may not capture the entire variability of clinical phenotypes. The European Scleroderma Trials and Research (EUSTAR) database includes data on a prospective cohort of SSc patients from 122 European referral centers. This study was undertaken to perform a cluster analysis of EUSTAR data to distinguish and characterize homogeneous phenotypes without any a priori assumptions, and to examine survival among the clusters obtained. METHODS: A total of 11,318 patients were registered in the EUSTAR database, and 6,927 were included in the study. Twenty-four clinical and serologic variables were used for clustering. RESULTS: Clustering analyses provided a first delineation of 2 clusters showing moderate stability. In an exploratory attempt, we further characterized 6 homogeneous groups that differed with regard to their clinical features, autoantibody profile, and mortality. Some groups resembled usual dcSSc or lcSSc prototypes, but others exhibited unique features, such as a majority of lcSSc patients with a high rate of visceral damage and antitopoisomerase antibodies. Prognosis varied among groups and the presence of organ damage markedly impacted survival regardless of cutaneous involvement. CONCLUSION: Our findings suggest that restricting subsets of SSc patients to only those based on cutaneous involvement may not capture the complete heterogeneity of the disease. Organ damage and antibody profile should be taken into consideration when individuating homogeneous groups of patients with a distinct prognosis. ispartof: ARTHRITIS & RHEUMATOLOGY vol:71 issue:9 pages:1553-1570 ispartof: location:United States status: published
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- 2019
39. Outcomes of patients with systemic sclerosis treated with rituximab in contemporary practice: a prospective cohort study
- Author
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Elhai, Muriel, Boubaya, Marouane, Distler, Oliver, Smith, Vanessa, Matucci-Cerinic, Marco, Alegre Sancho, Juan Jose, Truchetet, Marie-Elise, Braun-Moscovici, Yolanda, Iannone, Florenzo, Novikov, Pavel I., Lescoat, Alain, Siegert, Elise, Castellvi, Ivan, Airo, Paolo, Vettori, Serena, De Langhe, Ellen, Hachulla, Eric, Erler, Anne, Ananieva, Lidia, Krusche, Martin, Lopez-Longo, F. J., Distler, Joerg H. W., Hunzelmann, Nicolas, Hoffmann-Vold, Anna-Maria, Riccieri, Valeria, Hsu, Vivien M., Pozzi, Maria R., Ancuta, Codrina, Rosato, Edoardo, Mihai, Carina, Kuwana, Masataka, Saketkoo, Lesley Ann, Chizzolini, Carlo, Hesselstrand, Roger, Ullman, Susanne, Yavuz, Sule, Rednic, Simona, Caimmi, Cristian, Bloch-Queyrat, Coralie, Allanore, Yannick, Guiducci, Serena, Walker, Ulrich A., Kyburz, Diego, Lapadula, Giovanni, Maurer, Britta, Jordan, Suzana, Dobrota, Rucsandra, Becvar, Radim, Sierakowsky, Stanislaw, Bielecka, Otylia Kowal, Sulli, Alberto, Cutolo, Maurizio, Cuomo, Giovanna, Nicoara, Ileana, Kahan, Andre, Vlachoyiannopoulos, Panayiotis G., Montecucco, Carlo Maurizio, Caporali, Roberto, Stork, Jiri, Inanc, Murat, Carreira, Patricia E., Novak, Srdan, Czirjak, Laszlo, Varju, Cecilia, Kucharz, Eugene J., Kotulska, Anna, Kopec-Medrek, Magdalena, Widuchowska, Malgorzata, Cozzi, Franco, Rozman, Blaz, Mallia, Carmel, Coleiro, Bernard, Gabrielli, Armando, Farge, Dominique, Wu, Chen, Marjanovic, Zora, Faivre, Helene, Hij, Darin, Dhamadi, Roza, Wollheim, Frank, Scheja, Agneta, Wuttge, Dirk M., Andreasson, Kristofer, Martinovic, Duska, Balbir-Gurman, Alexandra, Trotta, F., Lo Monaco, Andrea, Pellerito, Raffaele, Mauriziano, Ospedale, Caramaschi, Paola, Morovic-Vergles, Jadranka, Black, Carol, Denton, Christopher, Damjanov, Nemanja, Henes, Jorg, Santamaria, Vera Ortiz, Heitmann, Stefan, Krasowska, Dorota, Hasler, Paul, Burkhardt, Harald, Himsel, Andrea, Bajocchi, Gianluigi, Da Silva, Jose Antonio Pereira, Salvador, Maria Joao, Stamenkovic, Bojana, Stankovic, Aleksandra, Selmi, Carlo Francesco, De Santis, Maria, Tikly, Mohammed, Denisov, Lev N., Herrick, Ariane, Mueller-Ladner, Ulf, Frerix, Marc, Tarner, Ingo, Scorza, Raffaella, Puppo, Francesco, Engelhart, Merete, Strauss, Gitte, Nielsen, Henrik, Damgaard, Kirsten, Szucs, Gabriela, Mendoza, Antonio Zea, de la Puente, Carlos, Giraldo, Sifuentes W. A., Midtvedt, Oyvind, Reiseter, Silje, Garen, Torhild, Launay, David, Valesini, Guido, Ionescu, Ruxandra Maria, Groseanu, Laura, Opris, Daniela, Cornateanu, Roxana Sfrent, Ionitescu, Razvan, Gherghe, Ana Maria, Soare, Alina, Gorga, Marilena, Bojinca, Mihai, Milicescu, Mihaela, Sunderkotter, Cord, Kuhn, Annegret, Sandorfi, Nora, Schett, Georg, Beyer, Christian, Meroni, Pierluigi, Ingegnoli, Francesca, Mouthon, Luc, De Keyser, Filip, Melsens, Karin, Cantatore, Francesco P., Corrado, Ada, Iversen, Line, von Muhlen, Carlos Alberto, Bohn, Jussara Marilu, Lonzetti, Lilian Scussel, Eyerich, Kilian, Hein, Rudiger, Knott, Elisabeth, Wiland, Piotr, Szmyrka-Kaczmarek, Magdalena, Sokolik, Renata, Morgiel, Ewa, Madej, Marta, Houssiau, Frederic A., Krummel-Lorenz, Brigitte, Saar, Petra, Aringer, Martin, Gunther, Claudia, Westhovens, Rene, Lenaerts, Jan, Anic, Branimir, Baresic, Marko, Mayer, Miroslav, Uprus, Maria, Otsa, Kati, Granel, Brigitte, Muller, Carolina de Souza, Radominski, Sebastiao C., Azevedo, Valderilio F., Jimenez, Sergio, Busquets, Joanna, Agachi, Svetlana, Groppa, Liliana, Chiaburu, Lealea, Russu, Eugen, Popa, Sergei, Zenone, Thierry, Pileckyte, Margarita, Mathieu, Alessandro, Vacca, Alessandra, Sampaio-Barros, Percival D., Yoshinari, Natalino H., Marangoni, Roberta G., Martin, Patricia, Fuocco, Luiza, Stebbings, Simon, Highton, John, Chapman, Peter, O'Donnell, John, Stamp, Lisa, Doube, Alan, Solanki, Kamal, Veale, Douglas, O'Rourke, Marie, Loyo, Esthela, Li, Mengtao, Mohamed, Walid Ahmed Abdel Atty, Amoroso, Antonio, Gigante, Antonietta, Oksel, Fahrettin, Yargucu, Figen, Tanaseanu, Cristina-Mihaela, Popescu, Monica, Dumitrascu, Alina, Tiglea, Isabela, Foti, Rosario, Chirieac, Rodica, Furst, Daniel, Villiger, Peter, Adler, Sabine, van Laar, Jacob, Kayser, Cristiane, Fathi, Nihal, Hassanien, Manal, Lefebvre, Paloma Garcia de la Pena, Rubio, Silvia Rodriguez, Exposito, Marta Valero, Chatelus, Emmanuel, Sibilia, Jean, Gottenberg, Jacques Eric, Chifflot, Helene, Litinsky, Ira, Emery, Paul, Buch, Maya, Del Galdo, Francesco, Venalis, Algirdas, Butrimiene, Irena, Venalis, Paulius, Rugiene, Rita, Karpec, Diana, Lasky, Joseph A., Cosentino, Vanesa, Kerzberg, Eduardo, Montoya, Fabiana, Bianchi, Washington, Carneiro, Sueli, Maretti, Giselle Baptista, Bianchi, Dante Valdetaro, Limonta, Massimiliano, Brucato, Antonio Luca, Lupi, Elide, Rosner, Itzhak, Rozenbaum, Michael, Slobodin, Gleb, Boulman, Nina, Rimar, Doron, Couto, Maura, Kahl, Sarah, Chen, Fei, McCloskey, Deborah, Malveaux, Halina, Spertini, Francois, Ribi, Camillo, Buss, Guillaume, Martin, Thierry, Guffroy, Aurelien, Poindron, Vincent, Chotchaeva, Fatima, Mukhin, Nikolay A., Moiseev, Sergey, Elhai, Muriel, Boubaya, Marouane, Distler, Oliver, Smith, Vanessa, Matucci-Cerinic, Marco, Alegre Sancho, Juan Jose, Truchetet, Marie-Elise, Braun-Moscovici, Yolanda, Iannone, Florenzo, Novikov, Pavel I., Lescoat, Alain, Siegert, Elise, Castellvi, Ivan, Airo, Paolo, Vettori, Serena, De Langhe, Ellen, Hachulla, Eric, Erler, Anne, Ananieva, Lidia, Krusche, Martin, Lopez-Longo, F. J., Distler, Joerg H. W., Hunzelmann, Nicolas, Hoffmann-Vold, Anna-Maria, Riccieri, Valeria, Hsu, Vivien M., Pozzi, Maria R., Ancuta, Codrina, Rosato, Edoardo, Mihai, Carina, Kuwana, Masataka, Saketkoo, Lesley Ann, Chizzolini, Carlo, Hesselstrand, Roger, Ullman, Susanne, Yavuz, Sule, Rednic, Simona, Caimmi, Cristian, Bloch-Queyrat, Coralie, Allanore, Yannick, Guiducci, Serena, Walker, Ulrich A., Kyburz, Diego, Lapadula, Giovanni, Maurer, Britta, Jordan, Suzana, Dobrota, Rucsandra, Becvar, Radim, Sierakowsky, Stanislaw, Bielecka, Otylia Kowal, Sulli, Alberto, Cutolo, Maurizio, Cuomo, Giovanna, Nicoara, Ileana, Kahan, Andre, Vlachoyiannopoulos, Panayiotis G., Montecucco, Carlo Maurizio, Caporali, Roberto, Stork, Jiri, Inanc, Murat, Carreira, Patricia E., Novak, Srdan, Czirjak, Laszlo, Varju, Cecilia, Kucharz, Eugene J., Kotulska, Anna, Kopec-Medrek, Magdalena, Widuchowska, Malgorzata, Cozzi, Franco, Rozman, Blaz, Mallia, Carmel, Coleiro, Bernard, Gabrielli, Armando, Farge, Dominique, Wu, Chen, Marjanovic, Zora, Faivre, Helene, Hij, Darin, Dhamadi, Roza, Wollheim, Frank, Scheja, Agneta, Wuttge, Dirk M., Andreasson, Kristofer, Martinovic, Duska, Balbir-Gurman, Alexandra, Trotta, F., Lo Monaco, Andrea, Pellerito, Raffaele, Mauriziano, Ospedale, Caramaschi, Paola, Morovic-Vergles, Jadranka, Black, Carol, Denton, Christopher, Damjanov, Nemanja, Henes, Jorg, Santamaria, Vera Ortiz, Heitmann, Stefan, Krasowska, Dorota, Hasler, Paul, Burkhardt, Harald, Himsel, Andrea, Bajocchi, Gianluigi, Da Silva, Jose Antonio Pereira, Salvador, Maria Joao, Stamenkovic, Bojana, Stankovic, Aleksandra, Selmi, Carlo Francesco, De Santis, Maria, Tikly, Mohammed, Denisov, Lev N., Herrick, Ariane, Mueller-Ladner, Ulf, Frerix, Marc, Tarner, Ingo, Scorza, Raffaella, Puppo, Francesco, Engelhart, Merete, Strauss, Gitte, Nielsen, Henrik, Damgaard, Kirsten, Szucs, Gabriela, Mendoza, Antonio Zea, de la Puente, Carlos, Giraldo, Sifuentes W. A., Midtvedt, Oyvind, Reiseter, Silje, Garen, Torhild, Launay, David, Valesini, Guido, Ionescu, Ruxandra Maria, Groseanu, Laura, Opris, Daniela, Cornateanu, Roxana Sfrent, Ionitescu, Razvan, Gherghe, Ana Maria, Soare, Alina, Gorga, Marilena, Bojinca, Mihai, Milicescu, Mihaela, Sunderkotter, Cord, Kuhn, Annegret, Sandorfi, Nora, Schett, Georg, Beyer, Christian, Meroni, Pierluigi, Ingegnoli, Francesca, Mouthon, Luc, De Keyser, Filip, Melsens, Karin, Cantatore, Francesco P., Corrado, Ada, Iversen, Line, von Muhlen, Carlos Alberto, Bohn, Jussara Marilu, Lonzetti, Lilian Scussel, Eyerich, Kilian, Hein, Rudiger, Knott, Elisabeth, Wiland, Piotr, Szmyrka-Kaczmarek, Magdalena, Sokolik, Renata, Morgiel, Ewa, Madej, Marta, Houssiau, Frederic A., Krummel-Lorenz, Brigitte, Saar, Petra, Aringer, Martin, Gunther, Claudia, Westhovens, Rene, Lenaerts, Jan, Anic, Branimir, Baresic, Marko, Mayer, Miroslav, Uprus, Maria, Otsa, Kati, Granel, Brigitte, Muller, Carolina de Souza, Radominski, Sebastiao C., Azevedo, Valderilio F., Jimenez, Sergio, Busquets, Joanna, Agachi, Svetlana, Groppa, Liliana, Chiaburu, Lealea, Russu, Eugen, Popa, Sergei, Zenone, Thierry, Pileckyte, Margarita, Mathieu, Alessandro, Vacca, Alessandra, Sampaio-Barros, Percival D., Yoshinari, Natalino H., Marangoni, Roberta G., Martin, Patricia, Fuocco, Luiza, Stebbings, Simon, Highton, John, Chapman, Peter, O'Donnell, John, Stamp, Lisa, Doube, Alan, Solanki, Kamal, Veale, Douglas, O'Rourke, Marie, Loyo, Esthela, Li, Mengtao, Mohamed, Walid Ahmed Abdel Atty, Amoroso, Antonio, Gigante, Antonietta, Oksel, Fahrettin, Yargucu, Figen, Tanaseanu, Cristina-Mihaela, Popescu, Monica, Dumitrascu, Alina, Tiglea, Isabela, Foti, Rosario, Chirieac, Rodica, Furst, Daniel, Villiger, Peter, Adler, Sabine, van Laar, Jacob, Kayser, Cristiane, Fathi, Nihal, Hassanien, Manal, Lefebvre, Paloma Garcia de la Pena, Rubio, Silvia Rodriguez, Exposito, Marta Valero, Chatelus, Emmanuel, Sibilia, Jean, Gottenberg, Jacques Eric, Chifflot, Helene, Litinsky, Ira, Emery, Paul, Buch, Maya, Del Galdo, Francesco, Venalis, Algirdas, Butrimiene, Irena, Venalis, Paulius, Rugiene, Rita, Karpec, Diana, Lasky, Joseph A., Cosentino, Vanesa, Kerzberg, Eduardo, Montoya, Fabiana, Bianchi, Washington, Carneiro, Sueli, Maretti, Giselle Baptista, Bianchi, Dante Valdetaro, Limonta, Massimiliano, Brucato, Antonio Luca, Lupi, Elide, Rosner, Itzhak, Rozenbaum, Michael, Slobodin, Gleb, Boulman, Nina, Rimar, Doron, Couto, Maura, Kahl, Sarah, Chen, Fei, McCloskey, Deborah, Malveaux, Halina, Spertini, Francois, Ribi, Camillo, Buss, Guillaume, Martin, Thierry, Guffroy, Aurelien, Poindron, Vincent, Chotchaeva, Fatima, Mukhin, Nikolay A., and Moiseev, Sergey
- Abstract
Objective To assess the safety and efficacy of rituximab in systemic sclerosis (SSc) in clinical practice. Methods We performed a prospective study including patients with SSc from the European Scleroderma Trials and Research (EUSTAR) network treated with rituximab and matched with untreated patients with SSc. The main outcomes measures were adverse events, skin fibrosis improvement, lung fibrosis worsening and steroids use among propensity score-matched patients treated or not with rituximab. Results 254 patients were treated with rituximab, in 58% for lung and in 32% for skin involvement. After a median follow-up of 2 years, about 70% of the patients had no side effect. Comparison of treated patients with 9575 propensity-score matched patients showed that patients treated with rituximab were more likely to have skin fibrosis improvement (22.7 vs 14.03 events per 100 person-years; OR: 2.79 [1.47-5.32]; p=0.002). Treated patients did not have significantly different rates of decrease in forced vital capacity (FVC)>10% (OR: 1.03 [0.55-1.94]; p=0.93) nor in carbon monoxide diffusing capacity (DLCO) decrease. Patients having received rituximab were more prone to stop or decrease steroids (OR: 2.34 [1.56-3.53], p<0.0001). Patients treated concomitantly with mycophenolate mofetil had a trend for better outcomes as compared with patients receiving rituximab alone (delta FVC: 5.22 [0.83-9.62]; p=0.019 as compared with controls vs 3 [0.66-5.35]; p=0.012). Conclusion Rituximab use was associated with a good safety profile in this large SSc-cohort. Significant change was observed on skin fibrosis, but not on lung. However, the limitation is the observational design. The potential stabilisation of lung fibrosis by rituximab has to be addressed by a randomised trial.
- Published
- 2019
40. Brain Abscesses Caused by Abiotrophia defectiva: Complication of Immunosuppressive Therapy in a Patient with Connective-tissue Disease
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Zenone, THIERRY and Durand, DENIS VITAL
- Published
- 2004
41. Rituximab-associated Vasculitis Flare: Incidence, Predictors, and Outcome
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Desbois, Anne Claire, primary, Biard, Lucie, additional, Sène, Damien, additional, Brocheriou, Isabelle, additional, Rouvier, Philippe, additional, Lioger, Bertrand, additional, Musset, Lucile, additional, Candon, Sophie, additional, Zenone, Thierry, additional, Resche-Rigon, Matthieu, additional, Piette, Jean-Charles, additional, Benameur, Neila, additional, Cacoub, Patrice, additional, and Saadoun, David, additional
- Published
- 2019
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42. Digital ulcers predict a worse disease course in patients with systemic sclerosis
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Mihai, Carina, Landewé, Robert, Van Der Heijde, Désirée, Walker, Ulrich A., Constantin, Paul I., Gherghe, Ana Maria, Ionescu, Ruxandra, Rednic, Simona, Allanore, Yannick, Avouac, Jéroˆme, Czirják, László, Hachulla, Eric, Riemekasten, Gabriela, Cozzi, Franco, Airò, Paolo, Cutolo, Maurizio, Mueller Ladner, Ulf, Matucci Cerinic, Marco, Launay, David, Dobrota, Rucsandra, Sfrent Cornateanu, Roxana, Zingarelli, Stefania, Pigatto, Erika, Cuomo, Giovanna, Caramaschi, Paola, Ananieva, Lidia, Ullman, Susanne, Iversen, Line, Gurman, Alexandra Balbir, Braun Moscovici, Yolanda, Carreira, Patricia E., Joven, Beatriz E., Minier, Tünde, Guiducci, Serena, Bellando Randone, Silvia, Pellerito, Raffaele, Hunzelmann, Nicolas, Tarner, Ingo H., Radominski, Sebastião Cezar, De Souza Müller, Carolina, Iannone, Florenzo, Henes, Jörg, Bancel, Dominique Farge, Damjanov, Nemanja, Ostojic, Predrag, Pozzi, Maria Rosa, Hesselstrand, Roger, Denton, Christopher, Krasowska, Dorota, Tikly, Mohammed, Riccieri, Valeria, Cantatore, Francesco Paolo, Corrado, Ada, Da Silva, José Antonio Pereira, Salvador, Maria João, Tyndall, Alan, Gabrielli, Armando, Distler, Oliver, Jordan, Suzan, Heitmann, Stefan, Burkhardt, Harald, Himsel, Andrea, Rozman, Blaz, Smith, Vanessa, Keyser, Filip De, Kalitena, Dusanka Martinovic, Radic, Mislav, Filipescu, Ileana, Petcu, Ana, Vlachoyiannopoulos, Panayiotis, Kucharz, Eugene J., Widuchowska, Malgorzata, Kopec Medrek, Magdalena, Kotulska, Anna, Szücs, Gabriella, Stankovic, Aleksandra, Stamenkovic, Bojana, Selmi, Carlo Francesco, Santis, Maria De, Marasini, Bianca, Coleiro, Bernard, Santamaria, Vera Ortiz, Westhovens, René, Becvár, Radim, Novak, Srdan, Engelhart, Merete, Meroni, Pierluigi, Ingegnoli, Francesca, Zeni, Silvana, Sulli, Alberto, Distler, Jörg, Yavuz, Sule, Montecucco, Carlomaurizio, Eyerich, Kilian, Krummel Lorenz, Brigitte, Zenone, Thierry, Midtvedt, Øyvind, Chizzolini, Carlo, Seidel, Matthias, Oleszowsky, Mara, Üprus, Maria, Opriş, Daniela, Groseanu, Laura, Bielecka, Otylia Kowal, Antonio, Zea Mendoza, Szechinski, Jacek, Morovic Vergles, Jadranka, Scorza, Raffaella, Puppo, Francesco, Mathieu, Alessandro, Anic, Branimir, Stork, Jiri, Stebbings, Simon, Inanc, Murat, Hasler, Paul, Von Mühlen, Carlos Alberto, Aringer, Martin, Popa, Sergei, Mengtao, Li, Rosato, Edoardo, University of Zurich, and Mihai, Carina
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Genetics and Molecular Biology (all) ,Lung Diseases ,Male ,0301 basic medicine ,Databases, Factual ,Epidemiology ,2745 Rheumatology ,Vital Capacity ,Disease ,Biochemistry ,Scleroderma ,Systemic autoimmune disease ,High morbidity ,0302 clinical medicine ,Cardiovascular Disease ,Immunology and Allergy ,Medicine (all) ,10051 Rheumatology Clinic and Institute of Physical Medicine ,Systemic Sclerosis ,Adult ,Aged ,Cardiovascular Diseases ,Disease Progression ,Female ,Hand Dermatoses ,Humans ,Hypertension, Pulmonary ,Kidney Diseases ,Middle Aged ,Multivariate Analysis ,Prognosis ,Proportional Hazards Models ,Pulmonary Diffusing Capacity ,Retrospective Studies ,Scleroderma, Systemic ,Skin Ulcer ,Stroke Volume ,Fingers ,Rheumatology ,Immunology ,Biochemistry, Genetics and Molecular Biology (all) ,Orvostudományok ,Pulmonary ,Hypertension ,2723 Immunology and Allergy ,medicine.medical_specialty ,610 Medicine & health ,Klinikai orvostudományok ,General Biochemistry, Genetics and Molecular Biology ,Disease course ,Databases ,03 medical and health sciences ,1300 General Biochemistry, Genetics and Molecular Biology ,Internal medicine ,Cox proportional hazards regression ,medicine ,In patient ,Factual ,030203 arthritis & rheumatology ,2403 Immunology ,business.industry ,Systemic ,medicine.disease ,030104 developmental biology ,Physical therapy ,business - Abstract
ObjectiveSystemic sclerosis (SSc) is a systemic autoimmune disease with high morbidity and significant mortality. There is a great need of predictors that would allow risk stratification of patients with SSc and ultimately initiation of treatment early enough to ensure optimal clinical results. In this study, we evaluated whether a history of digital ulcers (HDU) at presentation may be a predictor of vascular outcomes and of overall clinical worsening and death in patients with SSc.MethodsPatients from the EULAR Scleroderma Trials and Research (EUSTAR) database, satisfying at inclusion the 1980 American College of Rheumatology classification criteria for SSc, who had a follow-up of at least 3 years since baseline or who have died, were included in the analysis. HDU at presentation as a predictor of disease worsening or death was evaluated by Cox proportional hazards regression analysis.Results3196 patients matched the inclusion criteria (male sex 13.2%, 33.4% diffuse subset). At presentation, 1092/3196 patients had an HDU (34.1%). In multivariable analysis adjusting for age, gender and all parameters considered potentially significant, HDU was predictive for the presence of active digital ulcers (DUs) at prospective visits (HR (95% CI)): 2.41 (1.91 to 3.03), pConclusionsIn patients with SSc, HDU at presentation predicts the occurrence of DUs at follow-up and is associated with cardiovascular worsening and decreased survival.
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- 2015
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43. Incidences and risk factors of organ manifestations in the early course of systemic sclerosis: A longitudinal EUSTAR study
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Jaeger, Veronika K., Wirz, Elina G., Allanore, Yannick, Rossbach, Philipp, Riemekasten, Gabriela, Hachulla, Eric, Distler, Oliver, Airò, Paolo, Carreira, Patricia E., Gurman, Alexandra Balbir, Tikly, Mohammed, Vettori, Serena, Damjanov, Nemanja, Müller Ladner, Ulf, Distler, Jörg H. W., Mangtao, Li, Walker, Ulrich A., Ananieva, Lidia, Heitmann, Stefan, Rednic, Simona, Riccieri, Valeria, Szmyrka Kaczmarek, Magdalena, Farge, Dominique, Lapadula, Giovanni, Matucci Cerinic, Marco, Guiducci, Serena, Hunzelmann, Nicolas, Ricci, Massimo, Mihai, Carina, Veale, Douglas, Hesselstrand, Roger, Mariok, Eduardo, Smith, Vanessa, Tarner, Ingo H., Kucharz, Eugene J., Czirják, László, Martinovic, Duska, Solanki, Kamal, Ancuta, Codrina Mihaela, Sibilia, Jean, Paola, Caramaschi, Hassanien, Manal, Kahl, Sarah, Wigley, Frederick, Vanthuyne, Marie, Opris, Daniela, Radominski, Sebastião C., Monaco, Andrea Lo, Corrado, Ada, Koehm, Michaela, Codullo, Veronica, Radim, Bevcar, Loyo, Esthela, Üprus, Maria, Pellerito, Raffaele, Zenone, Thierry, Gabrielli, Armando, Kowal Bielecka, Otylia, Rozman, Blaz, Scorza, Raffaella, Saketkoo, Lesley Ann, Midtvedt, Oyvind, Von Mühlen, Carlos Alberto, Henes, Jörg, Branimir, Ani, Hasler, Paul, Yavuz, Sule, Adler, Sabine, Krummel Lorenz, Brigitte, Posa, Magdalena, Engelhart, Merete, Denton, Christopher, Krasowska, Dorota, Lefebvre, Paloma Garcia De La Peña, Cozzi, Franco, Mouthon, Luc, Rosato, Edoardo, Selmi, Carlo, Sancho, Juan José Alegre, Mallia, Carmel, Limonta, Massimiliano, Seidel, Matthias, Foti, Rosario, Stamp, Lisa, Ullman, Susanne, Stebbings, Simon, Santamaria, Vera Ortiz, Del Galdo, Francesco, De Langhe, Ellen, Mathieu, Alessandro, Sunderkötter, Cord, Eyerich, Kilian, Stamenkovic, Bojana, Novak, Srdan, Sampaio Barros, Percival D., Kayser, Cristiane, Litinsky, Ira, Couto, Maura, Jaeger, Veronika K., Wirz, Elina G., Allanore, Yannick, Rossbach, Philipp, Riemekasten, Gabriela, Hachulla, Eric, Distler, Oliver, Airã², Paolo, Carreira, Patricia E., Gurman, Alexandra Balbir, Tikly, Mohammed, Vettori, Serena, Damjanov, Nemanja, Mã¼ller ladner, Ulf, Distler, Jã¶rg H. W., Li, Mangtao, Walker, Ulrich A., Ananieva, Lidia, Heitmann, Stefan, Rednic, Simona, Riccieri, Valeria, Szmyrka kaczmarek, Magdalena, Farge, Dominique, Lapadula, Giovanni, Matucci cerinic, Marco, Guiducci, Serena, Hunzelmann, Nicola, Ricci, Massimo, Mihai, Carina, Veale, Dougla, Hesselstrand, Roger, Mariok, Eduardo, Smith, Vanessa, Tarner, Ingo H., Kucharz, Eugene J., Czirjã¡k, Lã¡szlã³, Martinovic, Duska, Solanki, Kamal, Ancuta, Codrina Mihaela, Sibilia, Jean, Paola, Caramaschi, Hassanien, Manal, Kahl, Sarah, Wigley, Frederick, Vanthuyne, Marie, Opris, Daniela, Radominski, Sebastiã£o C., Monaco, Andrea Lo, Corrado, Ada, Koehm, Michaela, Codullo, Veronica, Radim, Bevcar, Loyo, Esthela, Ãœprus, Maria, Pellerito, Raffaele, Zenone, Thierry, Gabrielli, Armando, Kowal bielecka, Otylia, Rozman, Blaz, Scorza, Raffaella, Saketkoo, Lesley Ann, Midtvedt, Oyvind, Von Mã¼hlen, Carlos Alberto, Henes, Jã¶rg, Branimir, Ani, Hasler, Paul, Yavuz, Sule, Adler, Sabine, Krummel lorenz, Brigitte, Posa, Magdalena, Engelhart, Merete, Denton, Christopher, Krasowska, Dorota, Lefebvre, Paloma Garcia De La Peã±a, Cozzi, Franco, Mouthon, Luc, Rosato, Edoardo, Selmi, Carlo, Sancho, Juan Josã© Alegre, Mallia, Carmel, Limonta, Massimiliano, Seidel, Matthia, Foti, Rosario, Stamp, Lisa, Ullman, Susanne, Stebbings, Simon, Santamaria, Vera Ortiz, Del Galdo, Francesco, De Langhe, Ellen, Mathieu, Alessandro, Sunderkã¶tter, Cord, Eyerich, Kilian, Stamenkovic, Bojana, Novak, Srdan, Sampaio barros, Percival D., Kayser, Cristiane, Litinsky, Ira, Couto, Maura, and University of Zurich
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Male ,Genetics and Molecular Biology (all) ,Pulmonology ,Blood Pressure ,Vascular Medicine ,Biochemistry ,Scleroderma ,Diagnostic Radiology ,0302 clinical medicine ,Retrospective Studie ,Longitudinal Studies ,lcsh:Science ,integumentary system ,Incidence ,Arteries ,Systolic Pressure ,3. Good health ,Echocardiography ,Cohort ,Regression Analysis ,Human ,medicine.medical_specialty ,Imaging Techniques ,Gastrointestinal Disease ,Immunology ,1100 General Agricultural and Biological Sciences ,Skin Diseases ,03 medical and health sciences ,FEV1/FVC ratio ,Rheumatology ,1300 General Biochemistry, Genetics and Molecular Biology ,Humans ,Autoantibodies ,Retrospective Studies ,Aged ,1000 Multidisciplinary ,Biochemistry, Genetics and Molecular Biology (all) ,Proportional hazards model ,lcsh:R ,Biology and Life Sciences ,Proteins ,medicine.disease ,Agricultural and Biological Sciences (all) ,Blood Vessels ,lcsh:Q ,Clinical Medicine ,Ejection Fraction ,Lung Diseases ,Kidney Disease ,Physiology ,Gastrointestinal Diseases ,lcsh:Medicine ,Longitudinal Studie ,Kaplan-Meier Estimate ,Medicine (all) ,Lung Disease ,Pericardial effusion ,Risk Factors ,Medizinische Fakultät ,Immune Physiology ,Ultrasound Imaging ,Medicine and Health Sciences ,030212 general & internal medicine ,Pulmonary Arteries ,Connective Tissue Diseases ,Immune System Proteins ,Pulmonary Hypertension ,Multidisciplinary ,Ejection fraction ,Radiology and Imaging ,Incidence (epidemiology) ,10051 Rheumatology Clinic and Institute of Physical Medicine ,Middle Aged ,Autoantibodie ,Heart Disease ,Kidney Diseases ,Female ,Anatomy ,Research Article ,Adult ,Heart Diseases ,Cardiology ,610 Medicine & health ,Research and Analysis Methods ,Antibodies ,Regression Analysi ,Autoimmune Diseases ,Diagnostic Medicine ,Internal medicine ,medicine ,ddc:610 ,030203 arthritis & rheumatology ,Scleroderma, Systemic ,business.industry ,Risk Factor ,Skin Disease ,Raynaud Disease ,Retrospective cohort study ,Surgery ,Cardiovascular Anatomy ,Clinical Immunology ,business - Abstract
Objective Systemic sclerosis (SSc) is a rare and clinically heterogeneous autoimmune disorder characterised by fibrosis and microvascular obliteration of the skin and internal organs. Organ involvement mostly manifests after a variable period of the onset of Raynaud's phenomenon (RP). We aimed to map the incidence and predictors of pulmonary, cardiac, gastrointestinal (GI) and renal involvement in the early course of SSc. Methods In the EUSTAR cohort, patients with early SSc were identified as those who had a visit within the first year after RP onset. Incident SSc organ manifestations and their risk factors were assessed using Kaplan-Meier methods and Cox regression analysis. Results Of the 695 SSc patients who had a baseline visit within 1 year after RP onset, the incident non-RP manifestations (in order of frequency) were: skin sclerosis (75%) GI symptoms (71%), impaired diffusing capacity for monoxide40mmHg (14%), and renal crisis (3%). In the heart, incidence rates were highest for diastolic dysfunction, followed by conduction blocks and pericardial effusion. While the main baseline risk factor for a short timespan to develop FVC impairment was diffuse skin involvement, for PAPsys>40mmHg it was higher patient age. The main risk factors for incident cardiac manifestations were anti-topoisomerase autoantibody positivity and older age. Male sex, anti-RNA-polymerase-III positivity, and older age were risk factors associated with incident renal crisis. Conclusion In SSc patients presenting early after RP onset, approximately half of all incident organ manifestations occur within 2 years and have a simultaneous rather than a sequential onset. These findings have implications for the design of new diagnostic and therapeutic strategies aimed to ‘widen' the still very narrow ‘window of opportunity'. They may also enable physicians to counsel and manage patients presenting early in the course of SSc more accurately.
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- 2016
44. Rituximab-associated Vasculitis Flare: Incidence, Predictors, and Outcome.
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Desbois, Anne Claire, Biard, Lucie, Sène, Damien, Brocheriou, Isabelle, Rouvier, Philippe, Lioger, Bertrand, Musset, Lucile, Candon, Sophie, Zenone, Thierry, Resche-Rigon, Matthieu, Piette, Jean-Charles, Benameur, Neila, Cacoub, Patrice, and Saadoun, David
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- 2020
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45. Update of EULAR recommendations for the treatment of systemic sclerosis
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UMC Utrecht, MS Reumatologie/Immunologie/Infectie, Infection & Immunity, Kowal-Bielecka, Otylia, Fransen, Jaap, Avouac, Jerome, Becker, Mike, Kulak, Agnieszka, Allanore, Yannick, Distler, Oliver, Clements, Philip, Cutolo, Maurizio, Czirjak, Laszlo, Damjanov, Nemanja, del Galdo, Francesco, Denton, Christopher P., Distler, Jörg H W, Foeldvari, Ivan, Figelstone, Kim, Frerix, Marc, Furst, Daniel E., Guiducci, Serena, Hunzelmann, Nicolas, Khanna, Dinesh, Matucci-Cerinic, Marco, Herrick, Ariane L., van den Hoogen, Frank, van Laar, Jacob M., Riemekasten, Gabriela, Silver, Richard, Smith, Vanessa, Sulli, Alberto, Tarner, Ingo, Tyndall, Alan, Welling, Joep, Wigley, Frederic, Valentini, Gabriele, Walker, Ulrich A., Zulian, Francesco, Müller-Ladner, Ulf, Daikeler, Thomas, Lanciano, Elisabetta, Becvár, Radim, Tomcik, Michal, Gindzienska-Sieskiewicz, Ewa, Iudici, Michele, Rednic, Simona, Vlachoyiannopoulos, Panayiotis G., Caporali, Roberto, Carreira, Patricia E., Novak, Srdan, Minier, Tünde, Kucharz, Eugene J., Gabrielli, Armando, Moroncini, Gianluca, Airo, Paolo, Hesselstrand, Roger, Martinovic, Duska, Radic, Mislav, Marasovic-Krstulovic, Daniela, Braun-Moscovici, Yolanda, Monaco, Andrea Lo, Morovic-Vergles, Jadranka, Culo, Melanie I., Henes, Jörg, Santamaria, Vera Ortiz, Heitmann, Stefan, Krasowska, Dorota, Michalska-Jakubus, Malgorzata, Seidel, Matthias F., Klinik, Medizinische, Hasler, Paul, Da Silva, José A Pereira, Salvador, Maria J., Stamenkovic, Bojana, Stankovic, Aleksandra, Tikly, Mohammed, Ananieva, Lidia P., Beretta, Lorenzo, Szucs, Gabriella, Szamosi, Szilvia, de la Puente Bujidos, Carlos, Midtvedt, Øyvind, Hoffmann-Vold, Anna Maria, Launay, David, Hachulla, Eric, Riccieri, Valeria, Ionescu, Ruxandra, Opris, Daniela, Mihai, Carina, Herrgott, Ilka, Beyer, Christian, Ingegnoli, Francesca, von Mühlen, Carlos Alberto, Alegre-Sancho, Juan José, Beltran-Catalan, Emma, Aringer, Martin, Fantana, Julia, Leuchten, Nicolai, Tausche, Anne Kathrin, Langhe, Ellen De, Vanthuyne, Marie, Anic, Branimir, Barešic, Marko, Mayer, Miroslav, üprus, Maria, Otsa, Kati, Yavuz, Sule, Granel, Brigitte, Jimenez, Sergio A., Popa, Serghei, Agachi, Svetlana, Zenone, Thierry, Stebbings, Simon, Dockerty, Joanne, Vacca, Alessandra, Schollum, Joanna, Veale, Douglas J., Toloza, Sergio, Xu, Dong, Olas, Jacek, Rosato, Edoardo, Foti, Rosario, Adler, Sabine, Dan, Diana, Wiesik-Szewczyk, Ewa, Olesinska, Marzena, Kayser, Cristiane, Fathi, Nihal, de la Peña Lefebvre, Paloma García, Imbert, Bernard, UMC Utrecht, MS Reumatologie/Immunologie/Infectie, Infection & Immunity, Kowal-Bielecka, Otylia, Fransen, Jaap, Avouac, Jerome, Becker, Mike, Kulak, Agnieszka, Allanore, Yannick, Distler, Oliver, Clements, Philip, Cutolo, Maurizio, Czirjak, Laszlo, Damjanov, Nemanja, del Galdo, Francesco, Denton, Christopher P., Distler, Jörg H W, Foeldvari, Ivan, Figelstone, Kim, Frerix, Marc, Furst, Daniel E., Guiducci, Serena, Hunzelmann, Nicolas, Khanna, Dinesh, Matucci-Cerinic, Marco, Herrick, Ariane L., van den Hoogen, Frank, van Laar, Jacob M., Riemekasten, Gabriela, Silver, Richard, Smith, Vanessa, Sulli, Alberto, Tarner, Ingo, Tyndall, Alan, Welling, Joep, Wigley, Frederic, Valentini, Gabriele, Walker, Ulrich A., Zulian, Francesco, Müller-Ladner, Ulf, Daikeler, Thomas, Lanciano, Elisabetta, Becvár, Radim, Tomcik, Michal, Gindzienska-Sieskiewicz, Ewa, Iudici, Michele, Rednic, Simona, Vlachoyiannopoulos, Panayiotis G., Caporali, Roberto, Carreira, Patricia E., Novak, Srdan, Minier, Tünde, Kucharz, Eugene J., Gabrielli, Armando, Moroncini, Gianluca, Airo, Paolo, Hesselstrand, Roger, Martinovic, Duska, Radic, Mislav, Marasovic-Krstulovic, Daniela, Braun-Moscovici, Yolanda, Monaco, Andrea Lo, Morovic-Vergles, Jadranka, Culo, Melanie I., Henes, Jörg, Santamaria, Vera Ortiz, Heitmann, Stefan, Krasowska, Dorota, Michalska-Jakubus, Malgorzata, Seidel, Matthias F., Klinik, Medizinische, Hasler, Paul, Da Silva, José A Pereira, Salvador, Maria J., Stamenkovic, Bojana, Stankovic, Aleksandra, Tikly, Mohammed, Ananieva, Lidia P., Beretta, Lorenzo, Szucs, Gabriella, Szamosi, Szilvia, de la Puente Bujidos, Carlos, Midtvedt, Øyvind, Hoffmann-Vold, Anna Maria, Launay, David, Hachulla, Eric, Riccieri, Valeria, Ionescu, Ruxandra, Opris, Daniela, Mihai, Carina, Herrgott, Ilka, Beyer, Christian, Ingegnoli, Francesca, von Mühlen, Carlos Alberto, Alegre-Sancho, Juan José, Beltran-Catalan, Emma, Aringer, Martin, Fantana, Julia, Leuchten, Nicolai, Tausche, Anne Kathrin, Langhe, Ellen De, Vanthuyne, Marie, Anic, Branimir, Barešic, Marko, Mayer, Miroslav, üprus, Maria, Otsa, Kati, Yavuz, Sule, Granel, Brigitte, Jimenez, Sergio A., Popa, Serghei, Agachi, Svetlana, Zenone, Thierry, Stebbings, Simon, Dockerty, Joanne, Vacca, Alessandra, Schollum, Joanna, Veale, Douglas J., Toloza, Sergio, Xu, Dong, Olas, Jacek, Rosato, Edoardo, Foti, Rosario, Adler, Sabine, Dan, Diana, Wiesik-Szewczyk, Ewa, Olesinska, Marzena, Kayser, Cristiane, Fathi, Nihal, de la Peña Lefebvre, Paloma García, and Imbert, Bernard
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- 2017
46. Risk of autoimmune diseases and human papilloma virus (HPV) vaccines: Six years of case-referent surveillance
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Grimaldi-Bensouda, Lamiae, primary, Rossignol, Michel, additional, Koné-Paut, Isabelle, additional, Krivitzky, Alain, additional, Lebrun-Frenay, Christine, additional, Clet, Johanna, additional, Brassat, David, additional, Papeix, Caroline, additional, Nicolino, Marc, additional, Benhamou, Pierre-Yves, additional, Fain, Olivier, additional, Costedoat-Chalumeau, Nathalie, additional, Courcoux, Marie-France, additional, Viallard, Jean-François, additional, Godeau, Bertrand, additional, Papo, Thomas, additional, Vermersch, Patrick, additional, Bourgault-Villada, Isabelle, additional, Breart, Gerard, additional, Abenhaim, Lucien, additional, Abbas, Firas, additional, Abdelmoumni, Abdelhakim, additional, Hilliquin, Pascal, additional, Requeda, Elisabeth, additional, Adoue, Daniel, additional, Agard, Christian, additional, Masseau, Agathe, additional, Aladjidi, Nathalie, additional, Fernandes, Helder, additional, Lemasson, Gwendal, additional, Perel, Yves, additional, Raymond, Isabelle, additional, Richer, Olivier, additional, Vital, Anne, additional, Allain-Launay, Emma, additional, Bru, Marie, additional, Thomas, Caroline, additional, Altman, Jean-Jacques, additional, Amsallem, Daniel, additional, Aras, Nazmiye, additional, Boukari, Latifato, additional, Dubrel, Marie, additional, Letellier, Edouard, additional, Lucidarme, Nadine, additional, Mekinian, Arsène, additional, Morin, Anne-Sophie, additional, Stirnemann, Jérôme, additional, Atlan, Catherine, additional, Audry, Dominique, additional, Augustin, Jérôme, additional, Bakir, Redouane, additional, Bartolucci, Pablo, additional, Chevalier, Xavier, additional, Guillaud, Constance, additional, Khellaf, Mehdi, additional, Limal, Nicolas, additional, Lousteau, Valentine, additional, Mahevas, Matthieu, additional, Méliksetyan, Gayane, additional, Michel, Marc, additional, Roumier, Mathilde, additional, Bayart, Sophie, additional, Bonnet, Fabrice, additional, Decaux, Olivier, additional, Bekherraz, Amine, additional, Brihaye, Benoit, additional, Dachez, Roger, additional, Daugas, Eric, additional, Hayem, Gilles, additional, Meyer, Olivier, additional, Pasqualoni, Elisa, additional, Sacre, Karim, additional, Travert, Florence, additional, Bellon, Hélène, additional, Beltrand, Jacques, additional, Lefrere, François, additional, Simon, Albane, additional, Benveniste, Olivier, additional, Bolgert, Francis, additional, De Paz, Raphael, additional, Demeret, Sophie, additional, Fautrel, Bruno, additional, Jacqueminet, Sophie, additional, Louapre, Céline, additional, Maillart, Elizabeth, additional, Morel, Nathalie, additional, Rigabert, Julie, additional, Bensaid, Philippe, additional, Berger, Claire, additional, Berquin, Patrick, additional, Le Moing, Anne-Gaëlle, additional, Berroir, Stéphane, additional, Besson, Gérard, additional, Boutte, Célia, additional, Casez, Olivier, additional, Bonnotte, Bernard, additional, Audia, Sylvain, additional, Bossu-Estour, Cécile, additional, Bourgarit, Anne, additional, Dupuy, Alain, additional, Keshmandt, Homa, additional, Bourre, Bertrand, additional, Brac, Aude, additional, Perrin, Agnès, additional, Pondarré, Corinne, additional, Villar-Fimbel, Sylvie, additional, Bruckert, Isabelle, additional, Cosson, Anne, additional, Magy-Bertrand, Nadine, additional, Tisserand, Guillaume, additional, Camu, William, additional, Carlander, Bertrand, additional, Morales, Raul Juntas, additional, Cances, Claude, additional, Pasquet, Marlene, additional, Castilla Lievre, Maria Angela, additional, Chabroux, Stephanie, additional, Charif, Mamoud, additional, Chatelus, Emmanuel, additional, Sibilia, Jean, additional, Chevrant-Breton, Jacqueline, additional, Clavel, Sylvaine, additional, Bille-Turc, Françoise, additional, Cohen, Jacques, additional, Courcoux, Marie France, additional, Leverger, Guy, additional, Machet, Laurent, additional, Cuisset, Jean-Marie, additional, Cony-Makhoul, Pascale, additional, Darsy, Paul, additional, Favre, Sandrine, additional, Giraud, Pierrick, additional, Leitenschenck, Laurence, additional, Monteiro, Irène, additional, Morati, Chafika, additional, DeSeze, Jérôme, additional, Dinulescu, Monica, additional, Dhaoui, Taher, additional, Dommange-Romero, Florence, additional, Drevard, Elisabeth, additional, Dupuis, Clémentine, additional, Dumuis, Marie-Laure, additional, Durand, Jean-Marc, additional, Farad, Samia, additional, Lecomte, Pierre, additional, Pierre, Peggy, additional, Fouyssac, Fanny, additional, Gaudin, Philippe, additional, Gautier, Alain, additional, Gellen-Dautremer, Justine, additional, Jarrin, Irène, additional, Richette, Pascal, additional, Georget, Emilie, additional, Gras, Pierre, additional, Moreau, Thibault, additional, Giraud, Eric, additional, Hacini, Maya, additional, Mayer, Anne, additional, Guillaumat, Cécile, additional, Guillaume, Séverine, additional, Guitton, Corinne, additional, Kone-Paut, Isabelle, additional, Marsaud, Céline, additional, Rossi, Linda, additional, Guyot, Marie-Hélène, additional, Hassler, Patrick, additional, Heimfert, Claude, additional, Heinzlef, Olivier, additional, Hillion, Brigitte, additional, Hocquelet, Catherine, additional, Husson, Helene, additional, Ichai, Pierre, additional, Jeziorski, Eric, additional, Deslandre, Chantal Job, additional, Le Guern, Véronique, additional, Kamenov, Kamen, additional, Kerlan, Véronique, additional, Lemoine, Philippe, additional, Misery, Laurent, additional, Pan-Petesch, Brigitte, additional, Labauge, Pierre, additional, Rodier, Michel, additional, Lacade, Chadi, additional, Razafimahefa, Berthe, additional, Lachgar, Karim, additional, Larmarau, Marie-Pierre, additional, Leblanc, Thierry, additional, Lefèbvre, Patrick, additional, Lejoyeux, Philippe, additional, Leske, Charles, additional, Ly, Kim, additional, Magy, Laurent, additional, Mansuy, Sylvie, additional, Marechaud, Richard, additional, Martin Negrier, Marie-Laure, additional, Sole, Guilhem, additional, Maupetit, Jean, additional, Mazingue, Françoise, additional, Mochon, Stéphanie, additional, Moktar, Blidi, additional, Morcamp, Donald, additional, Morlet-Barla, Nathalie, additional, Nicolas, Guillaume, additional, Pautot, Vivien, additional, Pellier, Isabelle, additional, Verret, Jean-Luc, additional, Outteryck, Olivier, additional, Pallot-Prades, Beatrice, additional, Paquet, Jean Michel, additional, Puechal, Xavier, additional, Sortais, Annie, additional, Pelletier, Jean, additional, Rico, Audrey, additional, Pez, Dominique, additional, Stankoff, Bruno, additional, Quittet, Philippe, additional, Rémy, Claude, additional, Roba, Eléna, additional, Rosario, Hélène, additional, Roudaut, Nathalie, additional, Sonnet, Emmanuel, additional, Ruel, Michel, additional, Sebban, Samuel, additional, Schaepelynck, Pauline, additional, Simonin, Marie-Jeanne, additional, Vial, Christophe, additional, Viallard, Jean-Francois, additional, Ladedan, Isabelle, additional, and Zenone, Thierry, additional
- Published
- 2017
- Full Text
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47. Effects and safety of rituximab in systemic sclerosis: An analysis from the European Scleroderma Trial and Research (EUSTAR) group
- Author
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MS Reumatologie/Immunologie/Infectie, Infection & Immunity, Jordan, Suzana, Distler, Jörg H W, Maurer, Britta, Huscher, Dörte, Van Laar, Jacob M., Allanore, Yannick, Distler, Oliver, Kvien, Tore K., Airo, Paolo, Sancho, Juan José Alegre, Ananjeva, Lidia, Ancuta, Codrina Michaela, Aringer, Martin, Balbir-Gurman, Alexandra, Cantatore, Francesco Paolo, Caramaschi, Paola, Chatelus, Emmanuel, Codullo, Veronica, Farge-Bancel, Dominique, Foti, Rosario, Gabrielli, Armando, Henes, Jörg, Herrgott, Ilka, Iannone, Florenzo, Ingegnoli, Francesca, Loyo, Esthela, Matucci-Cerinić, Marco, Mohamed, Walid Ahmed Abdel Atty, Müller-Ladner, Ulf, Palm, Øyvind, Popa, Sergiu, Riemekasten, Gabriela, Rednic, Simona, Rosato, Edoardo, Saracco, Marta, Scheja, Agneta, Smith, Vanessa, Mihai, Carina, Szucs, Gabriela, Tomšić, Matija, Valentini, Gabriele, Walker, Ulrich A., Westhovens, Rene, Yavuz, Sule Kurhan, Zenone, Thierry, MS Reumatologie/Immunologie/Infectie, Infection & Immunity, Jordan, Suzana, Distler, Jörg H W, Maurer, Britta, Huscher, Dörte, Van Laar, Jacob M., Allanore, Yannick, Distler, Oliver, Kvien, Tore K., Airo, Paolo, Sancho, Juan José Alegre, Ananjeva, Lidia, Ancuta, Codrina Michaela, Aringer, Martin, Balbir-Gurman, Alexandra, Cantatore, Francesco Paolo, Caramaschi, Paola, Chatelus, Emmanuel, Codullo, Veronica, Farge-Bancel, Dominique, Foti, Rosario, Gabrielli, Armando, Henes, Jörg, Herrgott, Ilka, Iannone, Florenzo, Ingegnoli, Francesca, Loyo, Esthela, Matucci-Cerinić, Marco, Mohamed, Walid Ahmed Abdel Atty, Müller-Ladner, Ulf, Palm, Øyvind, Popa, Sergiu, Riemekasten, Gabriela, Rednic, Simona, Rosato, Edoardo, Saracco, Marta, Scheja, Agneta, Smith, Vanessa, Mihai, Carina, Szucs, Gabriela, Tomšić, Matija, Valentini, Gabriele, Walker, Ulrich A., Westhovens, Rene, Yavuz, Sule Kurhan, and Zenone, Thierry
- Published
- 2015
48. Systemic Bartonella henselae Infection in Immunocompetent Adult Presenting as Fever of Unknown Origin
- Author
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Zenone, Thierry
- Subjects
Article Subject - Abstract
Systemic clinical presentations of infection caused by Bartonella henselae are rare in immunocompetent adults. We report four cases with hepatic and/or splenic involvement, presenting as fever of unknown origin. We discuss diagnosis and treatment of this infection. Bartonella henselae serology allows an easy diagnosis of hepatosplenic involvement in cat scratch disease, a clinical picture that appears to be underrecognized.
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- 2011
- Full Text
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49. A comparison between nailfold capillaroscopy patterns in adulthood in juvenile and adult-onset systemic sclerosis: A EUSTAR exploratory study
- Author
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Ingegnoli, Francesca, primary, Boracchi, Patrizia, additional, Gualtierotti, Roberta, additional, Smith, Vanessa, additional, Cutolo, Maurizio, additional, Foeldvari, Ivan, additional, Airò, Paolo, additional, Alegre-Sancho, Juan Jose, additional, Allanore, Yannick, additional, Ananieva, Lidia P., additional, Ancuta, Codrina, additional, Andrade, Luis Eduardo, additional, Aringer, Martin, additional, Becvar, Radim, additional, Bojinca, Mihai, additional, Butrimiene, Irena, additional, Cantatore, Francesco Paolo, additional, Caporali, Roberto, additional, Caramaschi, Paola, additional, Carreira, Patricia E., additional, Chirieac, Rodica, additional, Corrado, Ada, additional, Cosentino, Vanesa, additional, Cuomo, Giovanna, additional, Czirjak, Laszlo, additional, Da Silva, José Antonio Pereira, additional, la Peña Lefebvre, Paloma García de, additional, De Keyser, Filip, additional, de Souza Müller, Carolina, additional, Damgaard, Kirsten, additional, Damjanov, Nemanja, additional, Denisov, Lev N., additional, Distler, Oliver, additional, Doube, Alan, additional, Dumitrascu, Alina, additional, Engelhart, Merete, additional, Exposito, Marta Valero, additional, Eyerich, Kilian, additional, Farge-Bancel, Dominique, additional, Azevedo, Valderílio Feijó, additional, Foti, Rosario, additional, Frerix, Marc, additional, Gabrielli, Armando, additional, Garen, Torhild, additional, Gottschalk, Paola, additional, Groseanu, Laura, additional, Guiducci, Serena, additional, Günther, Claudia, additional, Hachulla, Eric, additional, Hein, Rüdiger, additional, Heitmann, Stefan, additional, Henes, Jörg, additional, Hesselstrand, Roger, additional, Highton, John, additional, Iannone, Florenzo, additional, Ionescu, Ruxandra Maria, additional, Kayser, Cristiane, additional, Karpec, Diana, additional, Kerzberg, Eduardo, additional, Kotulska, Anna, additional, Kopec-Medrek, Magdalena, additional, Kucharz, Eugene, additional, Krummel-Lorenz, Brigitte, additional, Lauffer, Felix, additional, Launay, David, additional, Li, Mengtao, additional, Litinsky, Ira, additional, Loyo, Esthela, additional, Cerinic, Marco Matucci, additional, Meroni, Pierluigi, additional, Midtvedt, Øyvind, additional, Mihai, Carmen Marina, additional, Montecucco, Carlomaurizio, additional, Montoya, Fabiana, additional, Morgiel, Ewa, additional, Mouthon, Luc, additional, Müller-Ladner, Ulf, additional, Nielsen, Henrik, additional, Opris, Daniela, additional, Ortiz-Santamaria, Vera, additional, Otsa, Kati, additional, Pileckyte, Margarita, additional, Pisarri, Simonetta, additional, Popescu, Monica, additional, Pozzi, Maria Rosa, additional, Puppo, Francesco, additional, Radominski, Sebastião Cezar, additional, Riccieri, Valeria, additional, Rosato, Edoardo, additional, Rozman, Blaz, additional, Rubio, Silvia Rodriguez, additional, Rugiene, Rita, additional, Saar, Petra, additional, Salvador, Maria João, additional, Seidel, Matthias, additional, Sokolik, Renata, additional, Solanki, Kamal, additional, Stamenkovic, Bojana, additional, Stankovic, Aleksandra, additional, Stebbings, Simon, additional, Strauss, Gitte, additional, Sulli, Alberto, additional, Szamosi, Szilvia, additional, Szechinski, Jacek, additional, Szmyrka-Kaczmarek, Magdalena, additional, Szücs, Gabriella, additional, Tanaseanu, Cristina-Mihaela, additional, Tiglea, Isabela, additional, Tyndall, Alan, additional, Ughi, Nicola, additional, Uprus, Maria, additional, Vacca, Alessandra, additional, Varju, Cecilia, additional, Venalis, Algirdas, additional, Venalis, Paulius, additional, Walker, Ulrich A., additional, Widuchowska, Malgorzata, additional, Wiland, Piotr, additional, Wuttge, Dirk M., additional, Zeni, Silvana, additional, and Zenone, Thierry, additional
- Published
- 2015
- Full Text
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50. Paragangliome avec syndrome inflammatoire biologique isolé : utilité de la tomographie par émission de positons
- Author
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Zenone, Thierry, Morelec, Isabelle, and Zenou, Éric
- Published
- 2011
- Full Text
- View/download PDF
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