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1. Somatic RIT1 delins in arteriovenous malformations hyperactivate RAS-MAPK signaling amenable to MEK inhibition

2. Myhre syndrome in adulthood: clinical variability and emerging genotype-phenotype correlations

3. Loss-of-function variants in ERF are associated with a Noonan syndrome-like phenotype with or without craniosynostosis

5. A GGC-repeat expansion in ZFHX3 encoding polyglycine causes spinocerebellar ataxia type 4 and impairs autophagy

7. Correction to: Assessment of gene–disease associations and recommendations for genetic testing for somatic variants in vascular anomalies by VASCERN-VASCA

9. Assessment of gene–disease associations and recommendations for genetic testing for somatic variants in vascular anomalies by VASCERN-VASCA

11. Heterozygosity for loss-of-function variants in LZTR1 is associated with isolated multiple café-au-lait macules

13. The seventh international RASopathies symposium: Pathways to a cure—expanding knowledge, enhancing research, and therapeutic discovery

15. Molecular and cellular evidence for the impact of a hypertrophic cardiomyopathy-associated RAF1 variant on the structure and function of contractile machinery in bioartificial cardiac tissues

18. Sudden cardiac death in childhood RASopathy-associated hypertrophic cardiomyopathy: Validation of the HCM risk-kids model and predictors of events

19. C-terminal variants in CDC42 drive type I interferon-dependent autoinflammation in NOCARH syndrome reversible by ruxolitinib

20. Aberrant phase separation and nucleolar dysfunction in rare genetic diseases

21. Clinical Outcome and Quality of Life of Multimodal Treatment of Extracranial Arteriovenous Malformations: The APOLLON Study Protocol

22. KrasP34R and KrasT58I mutations induce distinct RASopathy phenotypes in mice

23. Responsiveness of sphingosine phosphate lyase insufficiency syndrome to vitamin B6 cofactor supplementation.

24. The sixth international RASopathies symposium: Precision medicine-From promise to practice.

27. DeepGestalt - Identifying Rare Genetic Syndromes Using Deep Learning

29. Predisposing germline mutations in high hyperdiploid acute lymphoblastic leukemia in children

30. Activating Mutations of RRAS2 Are a Rare Cause of Noonan Syndrome

31. Proceedings of the fifth international RASopathies symposium: When development and cancer intersect

33. Nerve enlargement in patients with Noonan syndrome: A retrospective cohort study.

37. NFIB Haploinsufficiency Is Associated with Intellectual Disability and Macrocephaly

39. The clinical significance of A2ML1 variants in Noonan syndrome has to be reconsidered

40. Variants of SOS2 are a rare cause of Noonan syndrome with particular predisposition for lymphatic complications

42. Cancer incidence and spectrum among children with genetically confirmed Beckwith-Wiedemann spectrum in Germany: a retrospective cohort study

43. The 8th International RASopathies Symposium: Expanding research and care practice through global collaboration and advocacy

44. Somatic RIT1 indels identified in arteriovenous malformations hyperactivate RAS-MAPK signaling and are amenable to MEK inhibition

45. Biallelic inactivation of the NF1 tumour suppressor gene in juvenile myelomonocytic leukaemia: Genetic evidence of driver function and implications for diagnostic workup

46. GGC expansion in ZFHX3 causes SCA4 and impairs autophagy

49. Evolutionary conserved networks of human height identify multiple Mendelian causes of short stature

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