4 results on '"Zengye Liu"'
Search Results
2. Clinical Observation of Laser Peripheral Iridoplasty with Number of Laser Shots in the Treatment of Acute Angle-Closure Glaucoma
- Author
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Cheng Ma, Zengye Liu, Wei Zhao, Luning Hei, and Shuang Yao
- Subjects
genetic structures ,Article Subject ,Lasers ,Biomedical Engineering ,Humans ,Iris ,Health Informatics ,Surgery ,Laser Therapy ,sense organs ,Glaucoma, Angle-Closure ,eye diseases ,Biotechnology - Abstract
Objective. To quantitatively study the intraocular pressure (IOP) control and chamber angle opening degree of patients with acute angle-closure glaucoma (stage of attack) treated by laser peripheral iridoplasty (LPIP) with different numbers of laser shots, and to evaluate the efficacy and safety of different numbers of laser shots. Methods. Fifty-five patients (60 eyes) with acute angle-closure glaucoma treated in our hospital from May 2019 to December 2020 were selected as the research subjects. All patients had poor intraocular pressure control (≥40 mmHg) after IOP-lowering drug therapy. The patients were randomly divided into three groups, 20 eyes in each group, and underwent laser peripheral iridoplasty (LPIP) with different numbers of laser shots (group I: 35 laser shots, group II: 45 laser shots, and group III: 60 laser shots). The best-corrected visual acuity, IOP, corneal condition, and opening degree of anterior chamber angle (ACA), namely, the trabecular-iris angle (TIA), angle opening distance at 500 μm (AOD500), and complications of patients before LPIP, 2 hours after LPIP, and 24 hours after LPIP were observed, and the opening degree of ACA were quantitatively measured. Results. The corrected visual acuity of the three groups after LPIP was improved to varying degrees, and the IOP decreased, TIA and AOD500 were increased compared with those before operation, and the differences were statistically significant P < 0.05 . There were statistically significant differences between group II and group I P < 0.05 . Four eyes in group I underwent LPIP again due to increased IOP. In group III, iris hemorrhage occurred in one eye and iris depigmentation occurred in one eye, and there was no statistical difference compared with group II P > 0.05 . Conclusions. LPIP can effectively reduce preoperative IOP and increase ACA width in patients with persistent high IOP that failed to respond to drug therapy, and moderate numbers of laser shots can achieve satisfactory results and highest safety.
- Published
- 2022
- Full Text
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3. Visual impairment and blindness caused by retinal diseases: A nationwide register-based study.
- Author
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Chuandi Zhou, Shu Li, Luyao Ye, Chong Chen, Shu Liu, Hongxia Yang, Peng Zhuang, Zengye Liu, Hongwen Jiang, Jing Han, Yiping Jiang, Liqin Zhou, Xiyuan Zhou, Jun Xiao, Cangxia Zhang, Lihui Wen, Changjun Lan, Yuqing Wang, Tao Sun, and Li Jiang
- Subjects
BLINDNESS ,STATISTICS ,RETINAL degeneration ,MYOPIA ,CONFIDENCE intervals ,AGE distribution ,MULTIVARIATE analysis ,RISK assessment ,SEX distribution ,RETINAL vein occlusion ,DESCRIPTIVE statistics ,RESEARCH funding ,RETINAL diseases ,VISION disorders ,DIABETIC retinopathy ,RETINAL detachment ,DATA analysis software ,LOGISTIC regression analysis ,ODDS ratio ,DISEASE risk factors ,DISEASE complications - Abstract
Background Retinal disorders cause substantial visual burden globally. Accurate estimates of the vision loss due to retinal diseases are pivotal to inform optimal eye health care planning and allocation of medical resources. The purpose of this study is to describe the proportion of visual impairment and blindness caused by major retinal diseases in China. Methods A nationwide register-based study of vitreoretinal disease covering all 31 provinces (51 treating centres) of mainland China. A total of 28 320 adults diagnosed with retinal diseases were included. Participants underwent standardised ocular examinations, which included best-corrected visual acuity (BCVA), dilated-fundus assessments, and optical coherence tomography. Visual impairment and blindness are defined using BCVA according to the World Health Organization (WHO) (visual impairment: <20/63-≥20/400; blindness: <20/400) and the United States (visual impairment: <20/40-≥20/200; blindness: <20/200) definitions. The risk factors of vision loss were explored by logistic regression analyses. Results Based on the WHO definitions, the proportions for unilateral visual impairment and blindness were 46% and 18%, respectively, whereas those for bilateral visual impairment and blindness were 31% and 3.3%, respectively. Diabetic retinopathy (DR) accounts for the largest proportion of patients with visual impairment (unilateral visual impairment: 32%, bilateral visual impairment: 60%) and blindness (unilateral blindness: 35%; bilateral blindness: 64%). Other retinal diseases that contributed significantly to vision loss included age-related macular degeneration, myopic maculopathy, retinal vein occlusion, and rhegmatogenous retinal detachment and other macular diseases. Women (bilateral vision loss: P=0.011), aged patients (unilateral vision loss: 45-64 years: P<0.001, ≥65 years: P < 0.001; bilateral vision loss: 45-64 years: P = 0.003, ≥65 years: P < 0.001 (reference: 18-44 years)) and those from Midwest China (unilateral and bilateral vision loss: both P<0.001) were more likely to suffer from vision loss. Conclusions Retinal disorders cause substantial visual burden among patients with retinal diseases in China. DR, the predominant retinal disease, is accountable for the most prevalent visual disabilities. Better control of diabetes and scaled-up screenings are warranted to prevent DR. Specific attention should be paid to women, aged patients, and less developed regions. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
4. Correlation between serum homocysteine, folate, vitamin B6 and age-related cataract
- Author
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Shuang Yao, Weiwei Guo, Zengye Liu, Luning Hei, and Cheng Ma
- Subjects
medicine.medical_specialty ,Crystallography ,business.industry ,Serum homocysteine ,Clinical Biochemistry ,homocysteine ,folate ,Biochemistry ,vitamin b6 ,Correlation ,Endocrinology ,QD901-999 ,Internal medicine ,medicine ,Molecular Medicine ,Vitamin b6 ,Age-related cataract ,business ,age-related cataract - Abstract
Age-related cataracts (ARC) are the leading cause of visual impairment and blindness, affecting 16 million subjects globally. This work aimed to investigate the correlation of serum homocysteine (Hcy), folate, vitamin B6 (VitB6) and ARC. We prospectively enrolled 60 ARC, and 58 age-matched healthy controls in this study. The serum concentrations of Hcy were determined using a fully automatic biochemical analyzer and folate/VitB6 by enzyme-linked immunosorbent assay (ELISA). The diagnostic performance of serum Hcy, folate and VitB6 for ARC were evaluated by receiver operating characteristics (ROC). The mean serum levels of Hcy, folate and VitB6 from the control group were 9.8 ± 2.1 μmol/L, 17.4 ± 2.3 nmol/L, 42.3 ± 5.7 pmol/L, respectively. In comparison, the mean serum levels of Hcy, folate and VitB6 from the ARC group were 12.2 ± 2.5 μmol/L, 15.3 ± 2.6 nmol/L, 40.3 ± 5.1 pmol/L, respectively. Significant statistical difference (p
- Published
- 2019
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