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7. Using machine learning to predict perfusionists' critical decision-making during cardiac surgery.

Author

Dias, R. D., Zenati, M. A., Rance, G., Srey, Rithy, Arney, D., Chen, L., Paleja, R., Kennedy-Metz, L. R., and Gombolay, M.

Subjects
CARDIAC surgery, CARDIOPULMONARY bypass, DECISION making, OPERATING rooms, MACHINE learning, PATIENT safety
Abstract

The cardiac surgery operating room is a high-risk and complex environment in which multiple experts work as a team to provide safe and excellent care to patients. During the cardiopulmonary bypass phase of cardiac surgery, critical decisions need to be made and the perfusionists play a crucial role in assessing available information and taking a certain course of action. In this paper, we report the findings of a simulation-based study using machine learning to build predictive models of perfusionists' decision-making during critical situations in the operating room (OR). Performing 30-fold cross-validation across 30 random seeds, our machine learning approach was able to achieve an accuracy of 78.2% (95% confidence interval: 77.8% to 78.6%) in predicting perfusionists' actions, having access to only 148 simulations. The findings from this study may inform future development of computerised clinical decision support tools to be embedded into the OR, improving patient safety and surgical outcomes. [ABSTRACT FROM AUTHOR]

Published
2022
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9. Significance Of "Dominant" Uncinate Duct Dilatation In Ipmn: A New High-Risk Criterion

Author

AlMasri, S., primary, Zenati, M., additional, Dasyam, A., additional, Singhi, A., additional, Lee, K., additional, Slivka, A., additional, Mcgrath, K., additional, Chennat, J., additional, Fasanella, K., additional, Khalid, A., additional, Brand, R., additional, Sarkaria, S., additional, Das, R., additional, Bartlett, D., additional, Zeh, H., additional, and Zureikat, A., additional

Published
2020
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28. Results of heart transplantation by extending recipient selection criteria

Author

Ugolino LIVI, Milano A, Bortolotti U, Casula R, Zenati M, and Casarotto D

Subjects
Adult, Immunosuppression Therapy, Male, Postoperative Care, Contraindications, Patient Selection, Statistics as Topic, Middle Aged, Postoperative Complications, Italy, Risk Factors, Heart Transplantation, Humans, Female, Survivors
Abstract

From November 1985 to July 1993, 29 out of 241 patients (12%) who underwent heart transplantation (HTx) at our institution had one or more "classical" contraindications to HTx: ageor = 60 years (20 patients); insulin-dependent diabetes mellitus (5 patients); irreversible renal failure requiring combined heart-kidney transplantation (2 patients); previous surgery for malignancy (1 patient); familial hypercholesterolemia (1 patient) and active systemic infection (1 patient). The main indication for HTx was ischemic cardiomyopathy (21 patients, 61%). Immunosuppression regimen consisted of Cyclosporine and Azathioprine, oral prednisone being subsequently added in 6 patients because of persistent rejection. There were 2 perioperative deaths and one late death. Follow-up ranged from 1 to 88 months (mean, 28 +/- 20) with an actuarial survival at 5 years of 85 +/- 8%. Annual cardiac catheterization demonstrated normal graft function and coronary arteries in all. No significant differences in survival, incidence of rejection and infection, renal function and duration of hospitalization were found when these patients were compared with those with no contraindications to HTx. In conclusion, HTx can be performed with good early clinical results in selected patients with "classical" contraindications to HTx; longer follow-up, however, is needed to confirm whether extension of the recipient selection criteria justified.

Published
1994

32. Influence of marginal donors on early results after heart transplantation

Author

Milano, A., Livi, U., Casula, R., Bortolotti, U., Gambino, A., Zenati, M., Marialuisa Valente, Angelini, A., Thiene, G., and Casarotto, D.

Subjects
Adult, Immunosuppression Therapy, Male, Tissue and Organ Procurement, Adolescent, Resuscitation, Age Factors, Infant, Middle Aged, Tissue Donors, Heart Arrest, Survival Rate, Actuarial Analysis, Echocardiography, Child, Preschool, Heart Transplantation, Humans, Female, Child, Retrospective Studies
Published
1993

34. 555: Older Donor for Older Recipient in Lung Transplantation

Author

Toyoda, Y., primary, Bermudez, C., additional, Speziali, G., additional, Gilbert, S., additional, Bhama, J., additional, Gongora, E., additional, Garcia, L., additional, Zenati, M., additional, Zomak, R., additional, Zaldonis, D., additional, Johnson, B., additional, Crespo, M., additional, and Pilewski, J., additional

Published
2009
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