820 results on '"Zeitlin, J"'
Search Results
2. Identifying Newborns with Hypoxic-Ischemic Encephalopathy in Hospital Discharge Data: A Validation Study
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Ego, Anne, primary, Debillon, T., additional, Sourd, D., additional, Mitton, N., additional, Fresson, J., additional, and Zeitlin, J., additional
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- 2024
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3. Les courbes de croissance anté- et postnatales en France – recommandations pour la pratique clinique du Collège national des gynécologues et obstétriciens français (CNGOF) et de la Société française de néonatologie (SFN)
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Verspyck, E., Gascoin, G., Senat, M.-V., Ego, A., Simon, L., Guellec, I., Monier, I., Zeitlin, J., Subtil, D., and Vayssiere, C.
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- 2022
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4. Intra-articular depletion of macrophages increases acute synovitis and alters macrophage polarity in the injured mouse knee
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Bailey, K.N., Furman, B.D., Zeitlin, J., Kimmerling, K.A., Wu, C.-L., Guilak, F., and Olson, S.A.
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- 2020
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5. Preterm birth and stillbirth rates during COVID-19 pandemic: differences by socioeconomic status
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Zeitlin, J, primary, Philibert, M, additional, Rihs, T A, additional, Draušnik, Z, additional, Gatt, M, additional, Engiom, H M, additional, Racape, J, additional, Szamotulska, K, additional, Barros, H, additional, and Gissler, M, additional
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- 2023
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6. Are differences in caesarean section rates between countries in Europe decreasing or increasing?
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Velebil, P, primary, Tica, V, additional, Durox, M, additional, Nijhuis, J, additional, Alexander, S, additional, Zeitlin, J, additional, and Gissler, M, additional
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- 2023
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7. Antenatal Detection of Fetal Growth Restriction and Risk of Stillbirth: Population-Based Case-Control Study
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Ego, A., Monier, I., Skaare, K., and Zeitlin, J.
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- 2020
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8. Impact of the COVID-19 pandemic on perinatal health and perinatal health inequalities in Europe
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Zeitlin, J, primary, Philibert, M, additional, Rihs, TA, additional, Draušnik, Ž, additional, Gatt, M, additional, Engiom, HM, additional, Recape, J, additional, Szamotulska, K, additional, Barros, H, additional, and Gissler, M, additional
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- 2022
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9. Health-related quality of life among five-year-old extremely preterm children with motor disorders
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Aubert, AM, primary, Costa, R, additional, Johnson, S, additional, Ådén, U, additional, Pierrat, V, additional, Cuttini, M, additional, van Heijst, AF, additional, Maier, RF, additional, Sentenac, M, additional, and Zeitlin, J, additional
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- 2022
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10. Continuous perinatal health monitoring and analysis in Europe based on a federated analytic approach: a proof of concept study
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Philibert, M, primary, Amyx, M, additional, Durox, M, additional, Dimnjakovic, J, additional, Thissen, M, additional, Estupiñán-Romero, F, additional, Berna, E, additional, and Zeitlin, J, additional
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- 2022
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11. Revue de la littérature des courbes intra-utérines et de poids de naissance
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Monier, I., primary, Hocquette, A., additional, and Zeitlin, J., additional
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- 2022
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12. Achieving more with less: lessons from country-level analyses of caesarean delivery and perinatal outcomes in Europe
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Zeitlin, J, primary, Mortensen, L, additional, Nijhuis, JG, additional, Recio Alcaide, A, additional, Velebil, P, additional, Tica, V, additional, Mierzejewska, E, additional, Klungsoyr, K, additional, Donati, S, additional, and Macfarlane, A, additional
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- 2022
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13. Health-related quality of life of children born very preterm : a multinational European cohort study
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Kim, Sung Wook, Andronis, Lazaros, Seppänen, Anna-Veera, Aubert, Adrien M., Barros, Henrique, Draper, Elizabeth S., Sentenac, Mariane, Zeitlin, Jennifer, Petrou, Stavros, Lebeer, Jo, Van Reempts, Patrick, Bruneel, E., Cloet, E., Oostra, A., Ortibus, E., Sarrechia, Iemke, Boerch, K., Pedersen, P., Toome, L., Varendi, H., Männamaa, M., Ancel, P.Y., Burguet, A., Jarreau, P.H., Pierrat, V., Truffert, P., Maier, R.F., Zemlin, M., Misselwitz, B., Wohlers, L., Cuttini, M., Croci, I., Carnielli, V., Ancora, G., Faldella, G., Ferrari, F., van Heijst, A., Koopman-Esseboom, C., Gadzinowski, J., Mazela, J., Montgomery, A., Pikuła, T., Barros, H., Costa, R., Rodrigues, C., Aden, U., Draper, E.S., Fenton, A., Johnson, S.J., Mader, S., Thiele, N., Pfeil, J.M., Petrou, S., Kim, S.W., Andronis, L., Zeitlin, J., Aubert, A.M., Bonnet, C., El Rafei, R., Seppänen, A.V., and SHIPS Research Group
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RJ ,Public Health, Environmental and Occupational Health ,Human medicine ,RG - Abstract
Purpose This study aims to (1) describe the health-related quality of life (HRQoL) outcomes experienced by children born very preterm (28–31 weeks’ gestation) and extremely preterm ( Methods This investigation was based on data for 3687 children born at ™ GCS scores. A mediation analysis that applied generalised structural equation modelling explored the association between potential mediators and PedsQL™ GCS scores. Results The multi-level OLS regression (fully adjusted model) revealed that birth at ™ GCS score of 0.35, 3.71 and 5.87, respectively. The mediation analysis revealed that the indirect effects of BPD and severe non-respiratory morbidity on the total PedsQL™ GCS score translated into decrements of 1.73 and 17.56, respectively, at Conclusion The findings suggest that HRQoL is particularly impaired by extremely preterm birth and the concomitant complications of preterm birth such as BPD and severe non-respiratory morbidity.
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- 2022
14. Les femmes de Seine-Saint-Denis ont-elles un suivi prénatal différent de celui des autres femmes d’Île-de-France ?
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Carayol, M., Bucourt, M., Cuesta, J., Blondel, B., and Zeitlin, J.
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- 2014
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15. Mortalité néonatale en Seine-Saint-Denis : analyse des certificats de décès néonatals
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Carayol, M., Bucourt, M., Cuesta, J., Zeitlin, J., and Blondel, B.
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- 2014
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16. Chaînage d’enregistrements de séjours PMSI aux premiers certificats de santé : un test dans le Val d’Oise
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Lebreton, E., Vincelet, C., Chatignoux, E., Menguy, C., Crenn Hebert, C., Février, Y.-M., and Zeitlin, J.
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- 2014
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17. How do late terminations of pregnancy affect comparisons of stillbirth rates in Europe? Analyses of aggregated routine data from the Euro‐Peristat Project
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Blondel, B, Cuttini, M, Hindori‐Mohangoo, AD, Gissler, M, Loghi, M, Prunet, C, Heino, A, Smith, L, van der Pal‐de Bruin, K, Macfarlane, A, Zeitlin, J, Haidinger, Gerald, Alexander, Sophie, Pavlou, Pavlos, Velebil, Petr, Mortensen, Laust Hvas, Sakkeus, Luule, Lack, Nicholas, Antsaklis, Aris, Berbik, István, Ólafsdóttir, Helga Sól, Bonham, Sheelagh, Misins, Janis, Jaselioniene, Jone, Wagener, Yolande, Gatt, Miriam, Nijhuis, Jan, Klungsoyr, Kari, Szamotulska, Katarzyna, Barros, Henrique, Horga, Mihai, Cap, Jan, Tul, Nataša, Bolúmar, Francisco, Gottvall, Karin, and Berrut, Sylvie
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- 2018
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18. Gestational age at diagnosis of early‐onset fetal growth restriction and impact on management and survival: a population‐based cohort study
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Monier, I, Ancel, P‐Y, Ego, A, Guellec, I, Jarreau, P‐H, Kaminski, M, Goffinet, F, and Zeitlin, J
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- 2017
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19. The second European Perinatal Health Report: documenting changes over 6 years in the health of mothers and babies in Europe
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Zeitlin, J, Mohangoo, A D, Delnord, M, and Cuttini, M
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- 2013
20. Using Robson's Ten‐Group Classification System for comparing caesarean section rates in Europe: an analysis of routine data from the Euro‐Peristat study
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Zeitlin, J., Durox, M., Macfarlane, A. J., Alexander, S., Heller, G., Loghi, M., Nijhuis, J., Sól Ólafsdóttir, H., Mierzejewska, E., Gissler, M., Blondel, B., Haidinger, G., Klimont, J., Vandervelpen, G., Zhang, W-H., Jordanova, E., Kolarova, R., Filipovic‐Grcic, B., Drausnik, Z., Rodin, U., Kyprianou, T., Scoutellas, V., Velebil, P., Mortensen, L., Sakkeus, L., Heino, A., Chantry, A., Deneux Tharaux, C., Lack, N., Antsaklis, A., Berbik, I., Bonham, S., Kearns, K., Sikora, I., Cuttini, M., Misins, J., Zile, I., Isakova, J., Billy, A., Couffignal, S., Lecomte, A., Weber, G., Gatt, M., Achterberg, P., Broeders, L., Hindori‐Mohangoo, A., Akerkar, R., Klungsøyr, K., Szamotulska, K., Barros, H., Horga, M., Tica, V., Cap, J., Tul, N., Verdenik, I., Bolumar, F., Jané, M., Alcaide, A. R., Vidal, M. J., Zurriaga, O., Kallen, K., Nyman, A., Berrut, S., Riggenbach, M., Rihs, T. A., Smith, L., Woods, R., Delnord, M., Hocquette, A., RS: GROW - R4 - Reproductive and Perinatal Medicine, MUMC+: MA Obstetrie Gynaecologie (3), Obstetrie & Gynaecologie, and Instituto de Saúde Pública da Universidade do Porto
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medicine.medical_specialty ,ten-group classification system ,Epidemiology ,RJ ,medicine.medical_treatment ,Population ,RT ,03 medical and health sciences ,0302 clinical medicine ,Pregnancy ,RA0421 ,medicine ,Humans ,Caesarean section ,Ten‐Group Classification System ,education ,perinatal health indicators ,reproductive and urinary physiology ,education.field_of_study ,030219 obstetrics & reproductive medicine ,Cesarean Section ,Singleton ,business.industry ,Obstetrics ,Obstetrics and Gynecology ,Gestational age ,Original Articles ,Corrigenda ,Robson classification ,Ten group classification system ,Europe ,Caesarean Birth ,Data quality ,health information systems ,Female ,Original Article ,Caesarean birth ,Observational study ,RG ,business ,Live Birth - Abstract
Objective Robson's Ten Group Classification System (TGCS) creates clinically relevant sub‐groups for monitoring caesarean birth rates. This study assesses whether this classification can be derived from routine data in Europe and uses it to analyse national caesarean rates. Design Observational study using routine data. Setting Twenty‐seven EU member states plus Iceland, Norway, Switzerland and the UK. Population All births at ≥22 weeks of gestational age in 2015. Methods National statistical offices and medical birth registers derived numbers of caesarean births in TGCS groups. Main outcome measures Overall caesarean rate, prevalence and caesarean rates in each of the TGCS groups. Results Of 31 countries, 18 were able to provide data on the TGCS groups, with UK data available only from Northern Ireland. Caesarean birth rates ranged from 16.1 to 56.9%. Countries providing TGCS data had lower caesarean rates than countries without data (25.8% versus 32.9%, P = 0.04). Countries with higher caesarean rates tended to have higher rates in all TGCS groups. Substantial heterogeneity was observed, however, especially for groups 5 (previous caesarean section), 6, 7 (nulliparous/multiparous breech) and 10 (singleton cephalic preterm). The differences in percentages of abnormal lies, group 9, illustrate potential misclassification arising from unstandardised definitions. Conclusions Although further validation of data quality is needed, using TGCS in Europe provides valuable comparator and baseline data for benchmarking and surveillance. Higher caesarean rates in countries unable to construct the TGCS suggest that effective routine information systems may be an indicator of a country's investment in implementing evidence‐based caesarean policies. Tweetable abstract Many European countries can provide Robson's Ten‐Group Classification to improve caesarean rate comparisons., Tweetable abstract Many European countries can provide Robson's Ten‐Group Classification to improve caesarean rate comparisons.
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- 2021
21. Variability in the management and outcomes of extremely preterm births across five European countries: a population-based cohort study
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Smith, Lucy K, Blondel, Beatrice, Van Reempts, Patrick, Draper, Elizabeth S, Manktelow, Bradley N, Barros, Henrique, Cuttini, Marina, Zeitlin, Jennifer, Martens, E, Martens, G, Van Reempts, P, Boerch, K, Hasselager, A, Huusom, L, Pryds, O, Weber, T, Toome, L, Varendi, H, Ancel, PY, Blondel, B, Burguet, A, Jarreau, PH, Truffert, P, Maier, RF, Misselwitz, B, Schmidt, S, Gortner, L, Baronciani, D, Gargano, G, Agostino, R, DiLallo, D, Franco, F, Carnielli, V, Cuttini, M, Koopman-Esseboom, C, van Heijst, A, Nijman, J, Gadzinowski, J, Mazela, J, Graça, LM, Machado, MC, Rodrigues, Carina, Rodrigues, T, Bonamy, AK, Norman, M, Wilson, E, Boyle, E, Draper, ES, Manktelow, BN, Fenton, AC, Milligan, DWA, Zeitlin, J, Bonet, M, and Piedvache, A
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- 2017
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22. Changes in management policies for extremely preterm births and neonatal outcomes from 2003 to 2012: two population‐based studies in ten European regions
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Bonet, M, Cuttini, M, Piedvache, A, Boyle, EM, Jarreau, PH, Kollée, L, Maier, RF, Milligan, DWA, Van Reempts, P, Weber, T, Barros, H, Gadzinowki, J, Draper, ES, Zeitlin, J, Martens, E, Martens, G, Boerch, K, Hasselager, A, Huusom, L, Pryds, O, Ancel, PY, Blondel, B, Bréart, G, Gortner, L, Kuenzel, W, Misselwitz, B, Schmidt, S, Agostino, R, DiLallo, D, Franco, F, Paesano, R, Hukkelhoven, C, Hulscher, M, Koopman‐Esseboom, C, Van Heijst, A, Breborowicz, G, Gadzinowski, J, Mazela, J, Carrapato, M, Rodrigues, T, Konje, J, Manktelow, BN, Fenton, A, and Sturgiss, S
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- 2017
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23. Wide Differences in Mode of Delivery Within Europe: Risk-stratified Analyses of Aggregated Routine Data from the Euro-Peristat Study
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Macfarlane, A.J., Blondel, B., Mohangoo, A.D., Cuttini, M., Nijhuis, J., Novak, Z., Ólafsdóttir, H.S., and Zeitlin, J.
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- 2017
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24. Le programme de médicalisation du système d’information (PMSI) – processus de production des données, validité et sources d’erreurs dans le domaine de la morbidité maternelle sévère
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Chantry, A.A., Deneux-Tharaux, C., Bal, G., Zeitlin, J., Quantin, C., and Bouvier-Colle, M.-H.
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- 2012
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25. Évolution du nombre d'interruptions volontaires de grossesse (IVG) en France et impact de la pandémie COVID19
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Vilain, A., primary, Rey, S., additional, Zeitlin, J., additional, and Fresson, J., additional
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- 2022
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26. Cohort Profile: the Etude Epidémiologique sur les Petits Ages Gestationnels-2 (EPIPAGE-2) preterm birth cohort
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Lorthe, Elsa, Benhammou, Valérie, Marchand-Martin, Laetitia, Pierrat, Véronique, Lebeaux, Cécile, Durox, Mélanie, Goffinet, François, Kaminski, Monique, Ancel, Pierre-Yves, Astruc, D, Kuhn, P, Langer, B, Matis, J, Ramousset, C, Hernandorena, X, Chabanier, P, Joly-Pedespan, L, Rebola, M, Costedoat, M, Leguen, A, Martin, C, Lecomte, B, Lemery, D, Vendittelli, F, Rochette, E, Beucher, G, Dreyfus, M, Guillois, B, Toure, Y, Rots, D, Burguet, A, Couvreur, S, Gouyon, J, Sagot, P, Colas, N, Franzin, A, Sizun, J, Beuchée, A, Pladys, P, Rouget, F, Dupuy, R, Soupre, D, Charlot, F, Roudaut, S, Favreau, A, Saliba, E, Reboul, L, Aoustin, E, Bednarek, N, Morville, P, Verrière, V, THIRIEZ, G, Balamou, C, Ratajczak, C, Marpeau, L, Marret, S, Barbier, C, Mestre, N, Kayem, G, Durrmeyer, X, Granier, M, Lapillonne, A, Ayoubi, M, Baud, O, Carbonne, B, Foix L’Hélias, L, Jarreau, P, Mitanchez, D, Boileau, P, Duffaut, C, Cornu, L, Moras, R, Salomon, D, Medjahed, S, Ahmed, K, Boulot, P, Cambonie, G, Daudé, H, Badessi, A, Tsaoussis, N, Poujol, M, Bédu, A, Mons, F, Bahans, C, Binet, M, Fresson, J, Hascoët, J, Milton, A, Morel, O, Vieux, R, Hilpert, L, Alberge, C, Arnaud, C, Vayssière, C, Baron, M, Charkaluk, M, Subtil, D, Truffert, P, Akowanou, S, Roche, D, Thibaut, M, D’Ercole, C, Gire, C, Simeoni, U, Bongain, A, DESCHAMPS, M, Zahed, M, Branger, B, Rozé, J, Winer, N, Gascoin, G, Sentilhes, L, Rouger, V, Dupont, C, Martin, H, Gondry, J, Krim, G, Baby, B, Popov, I, Debeir, M, Claris, O, Picaud, J, Rubio-Gurung, S, Cans, C, Ego, A, Debillon, T, Patural, H, Rannaud, A, Janky, E, Poulichet, A, Rosenthal, J, Coliné, E, Cabrera, C, Favre, A, Joly, N, Stouvenel, A, Châlons, S, Pignol, J, Laurence, P, Lochelongue, V, Robillard, P, Samperiz, S, Ramful, D, Asadullah, H, Blondel, B, Bonet, M, Brinis, A, Coquelin, A, Delormel, V, Esmiol, S, Fériaud, M, Foix-L’Hélias, L, Khemache, K, Khoshnood, B, Onestas, L, Quere, M, Rousseau, J, Rtimi, A, Saurel-Cubizolles, M, Tran, D, Sylla, D, Vasante-Annamale, L, Zeitlin, J, Centre de Recherche Épidémiologie et Statistique Sorbonne Paris Cité (CRESS (U1153 / UMR_A_1125 / UMR_S_1153)), Conservatoire National des Arts et Métiers [CNAM] (CNAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Equipe 1 : EPOPé - Épidémiologie Obstétricale, Périnatale et Pédiatrique (CRESS - U1153), Conservatoire National des Arts et Métiers [CNAM] (CNAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Conservatoire National des Arts et Métiers [CNAM] (CNAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), CHU Trousseau [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), AP-HP - Hôpital Cochin Broca Hôtel Dieu [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Institut Pascal (IP), Centre National de la Recherche Scientifique (CNRS)-Université Clermont Auvergne (UCA)-Institut national polytechnique Clermont Auvergne (INP Clermont Auvergne), Université Clermont Auvergne (UCA)-Université Clermont Auvergne (UCA), CHU Estaing [Clermont-Ferrand], and CHU Clermont-Ferrand
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[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie ,[SDV.MHEP.GEO]Life Sciences [q-bio]/Human health and pathology/Gynecology and obstetrics ,ComputingMilieux_MISCELLANEOUS - Abstract
International audience
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- 2021
27. Comparison of the performance of estimated fetal weight charts for the detection of small‐ and large‐for‐gestational age newborns with adverse outcomes: a French population‐based study
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Monier, I, primary, Ego, A, additional, Benachi, A, additional, Hocquette, A, additional, Blondel, B, additional, Goffinet, F, additional, and Zeitlin, J, additional
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- 2021
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28. Research use cases measuring the impact of COVID-19 on population health
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Thißen, M, primary, Bernal-Delgado, E, additional, Rodriguez-Blazquez, C, additional, Estupiñán-Romero, F, additional, Forjaz, J, additional, Gonzalez-García, J, additional, Lyons, R, additional, Schmidt, A, additional, Seeling, S, additional, and Zeitlin, J, additional
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- 2021
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29. Wide differences in mode of delivery within Europe: risk-stratified analyses of aggregated routine data from the Euro-Peristat study
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Macfarlane, A J, Blondel, B, Mohangoo, A D, Cuttini, M, Nijhuis, J, Novak, Z, Ólafsdóttir, H S, and Zeitlin, J
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- 2016
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30. Employment, Working Conditions, and Preterm Birth: Results from the Europop Case-Control Survey
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Saurel-Cubizolles, M. J., Zeitlin, J., Lelong, N., Papiernik, E., Di Renzo, G. C., and Bréart, G.
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- 2004
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31. Producing valid statistics when legislation, culture, and medical practices differ for births at or before the threshold of survival: Report of a European workshop
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Smith, L. K., Blondel, B., Zeitlin, J., Haidinger, G., Alexander, S., Kolarova, R., Rodin, U., Kyprianou, T., Velebil, P., Mortensen, L., Sakkeus, L., Gissler, M., Heller, G., Lack, N., Antsaklis, A., Berbik, I., Olafsdottir, H., Bonham, S., Cuttini, M., Misins, J., Isakova, J., Wagener, Y., Gatt, M., Nijhuis, J., Klungsoyr, K., Szamotulska, K., Barros, H., Horga, M., Cap, J., Tul, N., Bolumar, F., Gottvall, K., Kallen, K., Berrut, S., Riggenbach, M., Macfarlane, A. J., Zeitlin, J, Delnord, M., Durox, M., Hindori-Mohangoo, A., RS: GROW - R4 - Reproductive and Perinatal Medicine, MUMC+: MA Obstetrie Gynaecologie (3), Obstetrie & Gynaecologie, Department of Health Sciences [Leicester], University of Leicester, Equipe 1 : EPOPé - Épidémiologie Obstétricale, Périnatale et Pédiatrique (CRESS - U1153), Centre de Recherche Épidémiologie et Statistique Sorbonne Paris Cité (CRESS (U1153 / UMR_A_1125 / UMR_S_1153)), Conservatoire National des Arts et Métiers [CNAM] (CNAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Conservatoire National des Arts et Métiers [CNAM] (CNAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Euro-Peristat Scientific Committee: Gerald Haidinger, Sophie Alexander, Urelija Rodin, Theopisti Kyprianou, Petr Velebil, Laust Mortensen, Luule Sakkeus, Mika Gissler, Günther Heller, Nicholas Lack, Aris Antsaklis, István Berbik, Helga Sól Ólafsdóttir, Sheelagh Bonham, Marina Cuttini, Janis Misins, Jelena Isakova, Yolande Wagener, Miriam Gatt, Jan Nijhuis, Katarzyna Szamotulska, Henrique Barros, Mihai Horga, Jan Cap, Natasa Tul, Francisco Bolúmar, Karin Gottvall, Karin Källén, Sylvan Berrut, Mélanie Riggenbach, Alison Macfarlane, Marie Delnord, Mélanie Durox, Ashna Hindori-Mohangoo, Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), and PHILIBERT, Marianne
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COUNTRIES ,Quality management ,Internationality ,STILLBIRTHS ,[SDV]Life Sciences [q-bio] ,Consensus Development Conferences as Topic ,Perinatal Death ,MEDLINE ,Legislation ,Gestational Age ,Population health ,DEFINITIONS ,03 medical and health sciences ,0302 clinical medicine ,FETAL-DEATH ,Environmental health ,Medicine ,Humans ,RATES ,ComputingMilieux_MISCELLANEOUS ,Perinatal Mortality ,Analysis of Variance ,030219 obstetrics & reproductive medicine ,business.industry ,Mortality rate ,International comparisons ,PRETERM BIRTHS ,Infant, Newborn ,Obstetrics and Gynecology ,Gestational age ,Public Reporting of Healthcare Data ,Stillbirth ,Quality Improvement ,3. Good health ,[SDV] Life Sciences [q-bio] ,Europe ,Vital Statistics ,Perinatal Care ,Commentary ,Gestation ,RG ,business - Abstract
Perinatal mortality is a major population health indicatorconveying important signals about the state of maternitycare and measures of the current and future health ofmothers and newborns. International comparisons are usedto encourage countries to improve their perinatal healthand health systems. However, extensive evidence highlightsmethodological challenges to ensuring valid and robustcomparisons, as a lack of standardised criteria can lead tobias and inappropriate inferences.One major issue is the wide international variation in the criteria for classification and registration of deaths as a stillbirth or neonatal death at the threshold of survival.Standard practice is to minimise this problem by using a gestational age cut-off of 24 or even 28 weeks for mortality rate calculations. However, this strategy excludes a significant number of stillbirths, at least one in five deaths before 24 weeks of gestation and over one in three deaths before 28 weeks.As the gestational age limit for initiation of neonatal care decreases, exclusion of these stillbirths limits the full evaluation ofcare provision and outcomes at early gestational ages. Fur-ther, it underestimates the burden of loss on parents’ men-tal and physical health.
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- 2019
32. Reforming EU Pesticides Regulation, Rebuilding Public Support: Evidence from Survey Experiments in Six Member States: an ACES policy report
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Zeitlin, J., Weimer, M., van der Duin, D., Kuhn, T., Jensen, M.D., Sustainable Global Economic Law (FdR), Political Economy and Transnational Governance (PETGOV, AISSR, FMG), ACELG (FdR), Faculteit der Rechtsgeleerdheid, FdR overig onderzoek, and Challenges to Democratic Representation (AISSR, FMG)
- Abstract
The authorization and use of pesticides in the European Union (EU) have become increasingly controversial and politically salient over the past decade. In particular the European Commission’s decision to re-authorize the use of glyphosate, the active substance in Bayer/Monsanto’s Roundup, after it had been classified a ‘probable human carcinogen’ by the International Agency for Research on Cancer (IARC), was highly controversial and triggered a lively debate on how to reform EU pesticide regulation. In this policy report, we assess whether and how specific reforms to decision-making procedures could impact public support for EU pesticides regulation, including acceptance of authorization decisions on controversial substances such as glyphosate. To do so, we first identified the main challenges of European pesticides regulation exposed by recent developments, including (but not limited to) the glyphosate controversy, as well as the actual and potential reforms proposed by the EU institutions, civil society organizations, academic commentators, and other stakeholders. We grouped these challenges and related reform proposals into four dimensions, namely: 1) the organization of the decision-making process; 2) the factors considered when authorizing pesticides; 3) sources of evidence and potential conflicts of interest; and 4) post-market monitoring and review of authorized pesticides. We then conducted a pair of linked online survey experiments on public attitudes toward reform of EU pesticides regulation in June 2020 among a representative sample of the adult population in six Member States (France, Germany, Italy, the Netherlands, Poland, and Sweden, n=9022). Our results show that the introduction of systematic post-authorization monitoring and review, and consideration of all relevant scientific studies in the authorization decision are the two most promising reforms to increase public support for pesticides regulation. Moreover, if a hypothetical glyphosate authorization decision is taken under a decision-making procedure that citizens (strongly) support, they are more likely to accept it even if they previously opposed this outcome. Our findings are particularly relevant given that glyphosate is currently again undergoing a renewal procedure in the EU.
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- 2021
33. Wide variation in severe neonatal morbidity among very preterm infants in European regions
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Bonamy, A, Zeitlin, J, Piedvache, A, Maier, R, Van Heijst, A, Varendi, H, Manktelow, B, Fenton, A, Mazela, J, Cuttini, M, Norman, M, Petrou, S, Van Reempts, P, Barros, H, and Draper, E
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macromolecular substances ,Healthcare improvement science Radboud Institute for Health Sciences [Radboudumc 18] - Abstract
Objective: To investigate the variation in severe neonatal morbidity among very preterm (VPT) infants across European regions and whether morbidity rates are higher in regions with low compared with high mortality rates.Design: Area-based cohort study of all births before 32 weeks of gestational age.Setting: 16 regions in 11 European countries in 2011/2012.Patients: Survivors to discharge from neonatal care (n=6422).Main outcome measures: Severe neonatal morbidity was defined as intraventricular haemorrhage grades III and IV, cystic periventricular leukomalacia, surgical necrotizing enterocolitis and retinopathy of prematurity grades >= 3. A secondary outcome included severe bronchopulmonary dysplasia (BPD), data available in 14 regions. Common definitions for neonatal morbidities were established before data abstraction from medical records. Regional severe neonatal morbidity rates were correlated with regional in-hospital mortality rates for live births after adjustment on maternal and neonatal characteristics.Results: 10.6% of survivors had a severe neonatal morbidity without severe BPD (regional range 6.4%23.5%) and 13.8% including severe BPD (regional range 10.0%-23.5%). Adjusted inhospital mortality was 13.7% (regional range 8.4%-18.8%). Differences between regions remained significant after consideration of maternal and neonatal characteristics (P< 0.001) and severe neonatal morbidity rates were not correlated with mortality rates (P= 0.50).Conclusion: Severe neonatal morbidity rates for VPT survivors varied widely across European regions and were independent of mortality rates.
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- 2019
34. Poor effectiveness of antenatal detection of fetal growth restriction and consequences for obstetric management and neonatal outcomes: a French national study
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Monier, I, Blondel, B, Ego, A, Kaminiski, M, Goffinet, F, and Zeitlin, J
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- 2015
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35. Migration to western industrialised countries and perinatal health: A systematic review
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Gagnon, A.J., Zimbeck, M., and Zeitlin, J.
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- 2009
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36. The influence of level of care on admission to neonatal care for babies of low-risk nullipara
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Le Ray, C., Zeitlin, J., Jarreau, P.H., Bréart, G., and Goffinet, F.
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- 2009
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37. Association between postnatal growth and neurodevelopmental impairment by sex at 2 years of corrected age in a multi-national cohort of very preterm children
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El Rafei, R, Jarreau, PH, Norman, M, Maier, RF, Barros, H, Van Reempts, P, Pedersen, P, Cuttini, M, Costa, R, Zemlin, M, Draper, ES, Zeitlin, J, EPICE Research Group, Instituto de Saúde Pública da Universidade do Porto, Equipe 1 : EPOPé - Épidémiologie Obstétricale, Périnatale et Pédiatrique (CRESS - U1153), Centre de Recherche Épidémiologie et Statistique Sorbonne Paris Cité (CRESS (U1153 / UMR_A_1125 / UMR_S_1153)), Conservatoire National des Arts et Métiers [CNAM] (CNAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Conservatoire National des Arts et Métiers [CNAM] (CNAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Collège doctoral [Sorbonne universités], Sorbonne Université (SU), Karolinska Institutet [Stockholm], Philipps University of Marburg, Federal University of Health Sciences of Porto Alegre = Universidade Federal de Ciências da Saúde de Porto Alegre (UFCSPA), Antwerp University Hospital [Edegem] (UZA), Hvidovre Hospital, Bambino Gesù Children’s Hospital [Rome, Italy], Saarland University [Saarbrücken], University of Leicester, and EPICE Research Group
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Male ,Pediatrics ,medicine.medical_specialty ,Population ,Gestational Age ,Infant, Premature, Diseases ,Critical Care and Intensive Care Medicine ,Weight Gain ,03 medical and health sciences ,0302 clinical medicine ,Corrected Age ,Sex Factors ,030225 pediatrics ,Prevalence ,Medicine ,Birth Weight ,Humans ,030212 general & internal medicine ,Postnatal growth ,Adverse effect ,education ,Growth Disorders ,education.field_of_study ,[SDV.MHEP.PED]Life Sciences [q-bio]/Human health and pathology/Pediatrics ,Nutrition and Dietetics ,business.industry ,Infant, Newborn ,Infant ,Confidence interval ,Patient Discharge ,3. Good health ,Very preterm ,Europe ,Suboptimal growth ,Multi national ,Neurodevelopmental impairment ,Very preterm infants ,Neurodevelopmental Disorders ,Child, Preschool ,Infant, Extremely Premature ,Cohort ,Birth Cohort ,Female ,[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie ,Human medicine ,business ,Extrauterine growth restriction - Abstract
Background & aims: Extra-uterine growth restriction (EUGR) is common among very preterm (VPT) infants and has been associated with impaired neurodevelopment. Some research suggests that adverse effects of EUGR may be more severe in boys. We investigated EUGR and neurodevelopment at 2 years of corrected age (CA) by sex in a VPT birth cohort. Methods: Data come from a population-based cohort of children born
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- 2021
38. International comparisons and holistic patient care
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Zeitlin, J, primary, Durox, M, additional, Macfarlane, A, additional, Alexander, S, additional, Heller, G, additional, Loghi, M, additional, Nijhuis, J, additional, Sól Ólafsdóttir, H, additional, Mierzejewska, E, additional, Gissler, M, additional, and Blondel, B, additional
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- 2021
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39. Dapagliflozin and Cardiovascular Outcomes in Type 2 Diabetes
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Wiviott S. D., Raz I., Bonaca M. P., Mosenzon O., Kato E. T., Cahn A., Silverman M. G., Zelniker T. A., Kuder J. F., Murphy S. A., Bhatt D. L., Leiter L. A., McGuire D. K., Wilding J. P. H., Ruff C. T., Nilsson G. I., Fredriksson M., Johansson P. A., Langkilde A. M., Sabatine M. S., Bansilal S., Furtado R., Fish M. P., Gabovitch D., Jevne A., Ahern S., Im K., Goodrich E. L., Lowe C., Fisher N., Gannon J., Trindade S., Towarowski A., Fox Y., Johnsson E., Ranft S., Faber B., Wallander M., Weiss A., Buskila A., Abola M. T. B., Ardissino D., Averkov O., Aylward P., Bode C., Bonnici F., Bonora E., Budaj A. J., Cernea S., Chiang C. E., Cooper M., Dalby A., Deerochanawong C., Dellborg M., Diaz R., Dimulescu D., Eliaschewitz F. G., Goudev A. R., Hadjadj S., Herrera M., Huo Y., Jermendy G., Ji L., Kadowaki T., Kiss R., Kooy A., Kumar K. M. P., Lewis B., Litwak L., Lopez-Sendon J., Ma R., Merlini P. A., Nauck M. A., Nguyen T. K., Nicolau J. C., Ostgren C. J., Ophuis T. O., Padilla F., Pais P., Park K. S., Parkhomenko A., Ray K., Rosenstock J., Ruda M., Satman I., Shestakova M., Smahelova A., Spinar J., Strojek K., Sy R., Tankova T., Theroux P., Tkac I., Van Gaal L., Wainstein J., Harrington R. A., Droller M. J., Lee K. L., Nesto R. W., Tuomilehto J., Hedlin H., Desai M., Sayfer I., Alexanian S., Awtry E., Bentley-Lewis R., Berger C. J., Croce K., Desai A., Garg R. K., Gelfand E., Gignac G., Goessling W., Ho C., Hochberg E., Lane A., Larrey D., Leeman D. E., Lewis J., Link M. S., McDonnell M. E., Norden A. D., Pande A., Rosenberg C., Rost N., Ruberg F., Schiff E., Silverman S., Singhal A., Wagner A., Wolpin B., Aizenberg D., Fernandez M., Sala J., Maffei L., Luquez C., Waitman J., Rista L., Nardone L., Sposetti G., Cantero M., Alvarisqueta A., Montana O., Cuadrado J., Cartasegna L., Baccaro C., Chertkoff A., Sanabria H., Vainstein N., Amerena J., Arya K., d'Emden M., Proietto J., Moses R., Colquhoun D., Stranks S., Lehman R., Hamilton A., Whelan A., Simpson R., Purnell P., Abhayaratna W., Hammett C., McKeirnan M., Sullivan D., Bach L., Hughes K., Mathieu C., Vercammen C., Scheen A., Duyck F., Cools F., De Wolf L., Verhaegen A., Nobels F., Missault L., Crenier L., Thoeng J., Wollaert B., Vandenbroucke M., Eliaschewitz F., Borges J. L. C., Turatti L., Lima F. G., dos Santos F., Kerr Saraiva J., Pereira M., Pereira A., Precoma D. B., Filho G. F. V., Reis G., Maia L. N., Bacheva T., Temelkova-Kurktschiev T., Maneva S., Stoyanovska B., Boshnyashka R., Stoykova Y., Georgiev D., Tagarev Z., Dimitrova E., Vitkina M., Yordanova L., Temelkova M., Vasileva S., Kuneva T., Zyumbyuleva M., Daskalova I., Genadieva V., Boyanov L., Farah G., Lazarova G., Georgieva M., Krasteva S., Slavcheva A., Yabroudi N., Veleva N., Zlateva A., Damyanova V., Elenkova A., Kotselova T., Genov K., Lyubenova L., Temelkova N., Harizanova B., Zaharieva S., Bajaj H., Goldenberg R., Aronson R., Twum-Barima D., Dumas R., Kouz S., Kaiser S. M., Ajala B., Cha J., Teitelbaum I., Chouinard G., Woo V., Dan Dattani I., Mazza G., Gaudet D., Poirier P., Conway J., Dion D., McKeough M., Manyari D., Harris S., St-Pierre B., Yale J. F., Landry D., Gupta M., Hramiak I., Lau D., DeGrace M., Gallo R., Montigny M., Dzongowski P., Liutkus J., Frechette A., Gosselin G., Sabbah E., Langlois M. F., Rabasa-Lhoret R., Bedard J., Hart R., Dowell A., Pandey A., O'Keefe D., Hill L., Weisnagel S. J., Muirhead N., Zimmermann R., Galiwango P., Tobe S., Priestman B., Zinman B., Ma J., Zhao X., Wang C., Zhang A., Dong Y., Dong X., Luo M., Guo J., Zheng Z., Li Y., Liang Y., Peng D., Maderic D., Spinarova L., Raclavska L., Ludka O., Rihacek I., Karasova J., Pelikanova M., Vlasakova H., Urbancova K., Zamrazil V., Hradec J., Vlasicova H., Racicka E., Okenka L., Naplava R., Skopecek J., Palova S., Krystl T., Pistek Z., Oznerova M., Andresova A., Sarbochova R., Taborska P., Petrova I., Stanek L., Reichert P., Lorenc Z., Szabo M., Petit C., Krempf M., Boye A., Dubois S., Clavel S., Gourdy P., Elbaz M., Jazayeri S., Gouet D., Verges B., Couffinhal T., Sendeski M., Klausmann G., Appel K., Pein M., Thieme R., Schumm-Draeger P., Jacob S., Toursarkissian N., Kleinecke-Pohl U., Tschope D., Ott P., Haak T., Nauck M., Derwahl K., Bugger H., Hui G., Tsang C., Zilahi Z., Puski L., Vangel S., Fulop T., Pall K., Hidvegi T., Revesz K., Koranyi L., Kajetan M., Kerenyi Z., Penzes J., Herczeg B., Laszloczky A., Turi T., Rapi J., Pentek Z., Gaal Z., Winkler G., Percs E., Czigany A., Harcsa E., Gurzo M., Tassaly J., Horthy R., Petro G., Farago K., Muller G., Varju I., Kirschner R., Kiss I., Bakai J., Kancz S., Marton Z., Kodur R., Yajnik C., Thomas N., Ayyar V., Iyengar P., Bashkin A., Daoud D., Itzhak B., Katz A., Tsur A., Nikolsky E., Atar S., Grossman A., Klainman E., Tsalihin D., Shotan A., Turgeman Y., Ferrario M., Merlini P., Piatti P., Zenari L., Trevisan R., Bosco B., Di Lorenzo L., Mannucci E., Avogaro A., Reimers B., Trimarco B., Silvestri O., Salvioni A., Nakagawa H., Sueyoshi A., Fukuda K., Yasumoto H., Matsubayashi S., Kawajiri K., Togashi Y., Senokuchi T., Ohta Y., Yamauchi T., Node K., Alcocer Gamba M., Herrera Marmolejo M., De los Rios Ibarra M., Gonzalez Galvez G., Garcia Cantu E., Leguizamo Dimas A., Luna Ceballos R., Medina Pech C., Stobschinski de Alba C., Gonzalez Gonzalez J., Padilla Padilla F., Fanghanel Salmon G., Robles Torres F., Lopez Rosas E., Pelayo Orozco E., Banda Elizondo R., Escalona Caamano A., Frenk Baron P., Aguilar Salinas C., Mustieles Rocha C., Vidrio Velazquez M., Rodriguez Briones I., Saldate Alonso M., Velasco Sanchez R., Groenemeijer B., Ronner E., Kuijper A., Strikwerda S., Van Kempen W., Gijsbers S., Oude Ophuis A., Swart H., Hoogenberg K., Hovens M., van Hessen M., Westerink J., Kragten J., Nierop P., Bax W., Hartong S., Nieuwdorp M., Gonkel F., Al Windy N., Troquay R., Schaafsma H., Lieverse A., Knufman N., Tirador L., Guenon M., Ferrolino A., Atilano A., Aportadera M., Que M., Denopol M., Tolentino M., Jimeno C., Wee J., Mirasol R., Panelo A., Roxas D., Abola M., Palmes P., Silva A., Salvador D., Rosita R., Maravilla L., Rogelio G., Pacheco E., Tin Hay L., Prado J., Krzyzagorska E., Witek R., Miklaszewicz B., Sudnik W., Pomiecko W., Bochenek A., Fares I., Wujkowski M., Korol M., Powierza S., Goch A., Miekus P., Siegel A., Skierkowska J., Romanczuk P., Cygler J., Landa K., Szyprowska E., Stachlewski P., Czerski T., Pawlowicz L., Sowinski D., Romanowski L., Rudzki H., Skorski M., Jasiel-Wojculewicz H., Stasiewski A., Budaj A., Kania G., Mirek-Bryniarska E., Wojnowski L., Korzeniak R., Oh T., Park K., Lee M., Lee K., Jang H., Kim S., Ku B., Cha B., Son H., Lee I., Park J., Yu S., Shon H., Rhee E., Cho J., Park T., Nam J., Pintilei E., Popescu A., Nafornita V., Gutu O., Dumitrescu A., Bala C., Caceaune E., Mindrescu N., Morosanu M., Bradescu O., Munteanu M., Voitec M., Vlaiculescu M., Hancu N., Diaconu Sotropa M., Lupu S., Mateescu A., Carlan L., Marton R., Lupusoru D., Mot A., Coman A., Zaharie D., Rebrov A., Shutemova E., Bolieva L., Khalimov Y., Statsenko M., Galyavich A., Koziolova N., Shapovalova Y., Pavlysh E., Strongin L., Vertkin A., Vishneva E., Pavlova M., Khasanov N., Antsiferov M., Gavrisheva I., Sokolova N., Vorobyev S., Morugova T., Sinitsina I., Ezhov A., Kobalava Z., Belenkiy D., Supryadkina T., Kazakov Y., Oschepkova E., Dreval A., Novikova T., Vishnevsky A., Chizhov D., Akatova E., Vorokhobina N., Ivanov I., Dudinskaya E., Konstantinov V., Kanderkova D., Pavlik L., Raslova K., Paulovic V., Babikova J., Belesova K., Merciakova M., Truban J., Vargova A., Fabryova L., Slovenska M., Plasil R., Tomasova L., Kollarova D., Spodniakova D., Kosikova M., Dzuponova J., Kurcova I., Skripova D., Gabrisova A., Kalinova S., Ranjith N., Burgess L., Mitha I., Conradie M., Distiller L., Pillai P., Pillay S., Horak A., Nethononda R., van den Berg E., Nortje H., Bayat J., Corbett C., Abelson M., van Zyl L., Pillay T., Wing J., Kapp C., Hidalgo Urbano R., Gonzalez Juanatey J., Blanco Coronado J., Bruguera Cortada J., Ferreiro Gutierrez J., Quesada Simon M., Castro A., Delgado Alvarez E., Freixa R., Boada A., Larnefeldt H., Mooe T., Koskinen P., Lagerback P., Linderfalk C., Liu B., Berndtsson Blom K., Tengmark B., Lindholm C., Ostgren C., Oweling M., Albertsson P., Alvarsson M., Fant S., Berglund O., Hsia C., Chiang C., Fang C., Ueng K., Wang K., Lai W., Mamanasiri S., Wongvipaporn C., Kuanprasert S., Thongsri T., Srimahachota S., Boonyavarakul A., Suwanwalaikorn S., Tantiwong P., Sritara P., Sriwijitkamol A., Sanguanwong S., Chotinaiwattarakul C., Piyayotai D., Balci M., Orbay E., Saygili F., Oguz A., Altuntas Y., Comlekci A., Karpenko O., Tkach S., Vlasenko M., Fushtey I., Pertseva T., Reshotko D., Mostovoy Y., Vizir V., Kraiz I., Amosova K., Batushkin V., Tseluyko V., Koval O., Strang C., Bodalia B., Pieters R., Turner W., Asamoah-Owusu N., White C., Calvert J., McNally D., Jones N., McKaig G., Thompson J., Mohr S., Simpson H., Conn P., McCoye A., Rivero O., Yazdani S., Ince C., Zeitlin J., Wharton T., Platt G., Anderson R. J., Angueira-Serrano E., Lillestol M., Hanlon B., Soufer J., Garcia B., Iteld B., Venugopal C., Ahmed A., Duardo-Guerra Y., Jetty P., Miranda A., Wahlen J., Lederman S., Cohen K., Lake L., French W. J., Tahirkheli N., Baker S., Stoltz R., Wilson J., Nadar V., Brown J., Larrain G., Wiseman A., Ruoff G., Williams M., Tan A., Hartman I., Singh N., Graf R., Wakefield P., McNeill R., Byars W., Reyes Almodovar R., Jones S., Kantaros L., Hegedosh N., Graves M., Bernstein M., Falkowski S., Bialow M., Paraschos A., Dagher G., Arif A., Condit J., Chaykin L., Grunstra B., Earl J., Unks D., Srivastava S., Benson M., Huffman C., Miller G., Willis J., Bender K., Martin E., Blackmore R., Rohr K., Chilka S., Gadowski G., Fitz-Patrick D., Benjamin S., Morin D., Zias Dilena A., Acosta R., Claassen D., Miranda F., Raad G., Inzerello A., Porter J., Bhattacharya A., Gutmann J., Korpas D., Syed M., Zieve F., Raisinghani A., Alam S., Bartkowiak A., Boccalandro F., Talano J., Mercado A., Krichmar P., Oldfield C., Adams K., Gorman T., Lewis D., Shah R., Shockey G., Lefebvre G., Andrawis N., Tami L., Bittar N., Khan M. S., Rink L., Hendrix E., Wood J., Robinson J., Pavon H., Irfan M., Gonzalez E., Singal R., Shore K., Saba F., Bianco J., Erickson B., Gorson D., Puri S., Arauz-Pacheco C., Forman S., Akyea-Djamson A., Lieber I., Barker B., Desai P., Sotolongo C., Steinhoff J., Hill R., Radin M., Patel R., Lieberman S., Wenocur H., Dagogo-Jack S., Lupovitch S., Ison R., Bacharach J. M., Diogo J., Mazzella M., Greenwald J., Quadrel M., Mayer N., Datu J., McCartney M., Bruce T., Singal D., Turner J., Videau B., Fritz R., Fox D., Calatayud G., Sheldon W., Kereiakes D., Thomas J., Salacata A., McCullum K., Harris B., de Souza J., Rahman A., Blumenthal S., Narayan P., Bloch M., Augenbraun C., Bernstein R., Perlman R., Berman J., LaBryer L., Wynne A., Fish J., Zarich S., Gabra N., Popeil L., Hermany P., Barreto A., Pomposini D., Gonzalez-Campoy J. 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B., Tran Q. K., Tran N., Nguyen D., Nguyen V., Brigham & Women’s Hospital [Boston] (BWH), Harvard Medical School [Boston] (HMS), VA Boston Healthcare System, Turbulence Research Laboratory [Goteborg], Chalmers University of Technology [Göteborg], Wiviott, S, Raz, I, Bonaca, M, Mosenzon, O, Kato, E, Cahn, A, Silverman, M, Zelniker, T, Kuder, J, Murphy, S, Bhatt, D, Leiter, L, Mcguire, D, Wilding, J, Ruff, C, Nilsson, G, Fredriksson, M, Johansson, P, Langkilde, A, Sabatine, M, Bansilal, S, Furtado, R, Fish, M, Gabovitch, D, Jevne, A, Ahern, S, Im, K, Goodrich, E, Lowe, C, Fisher, N, Gannon, J, Trindade, S, Towarowski, A, Fox, Y, Johnsson, E, Ranft, S, Faber, B, Wallander, M, Weiss, A, Buskila, A, Abola, M, Ardissino, D, Averkov, O, Aylward, P, Bode, C, Bonnici, F, Bonora, E, Budaj, A, Cernea, S, Chiang, C, Cooper, M, Dalby, A, Deerochanawong, C, Dellborg, M, Diaz, R, Dimulescu, D, Eliaschewitz, F, Goudev, A, Hadjadj, S, Herrera, M, Huo, Y, Jermendy, G, Ji, L, Kadowaki, T, Kiss, R, Kooy, A, Kumar, K, 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C, Wee, J, Mirasol, R, Panelo, A, Roxas, D, Palmes, P, Silva, A, Salvador, D, Rosita, R, Maravilla, L, Rogelio, G, Pacheco, E, Tin Hay, L, Prado, J, Krzyzagorska, E, Witek, R, Miklaszewicz, B, Sudnik, W, Pomiecko, W, Bochenek, A, Fares, I, Wujkowski, M, Korol, M, Powierza, S, Goch, A, Miekus, P, Siegel, A, Skierkowska, J, Romanczuk, P, Cygler, J, Landa, K, Szyprowska, E, Stachlewski, P, Czerski, T, Pawlowicz, L, Sowinski, D, Romanowski, L, Rudzki, H, Skorski, M, Jasiel-Wojculewicz, H, Stasiewski, A, Kania, G, Mirek-Bryniarska, E, Wojnowski, L, Korzeniak, R, Oh, T, Lee, M, Jang, H, Kim, S, Ku, B, Cha, B, Son, H, Lee, I, Park, J, Yu, S, Shon, H, Rhee, E, Cho, J, Park, T, Nam, J, Pintilei, E, Popescu, A, Nafornita, V, Gutu, O, Dumitrescu, A, Bala, C, Caceaune, E, Mindrescu, N, Morosanu, M, Bradescu, O, Munteanu, M, Voitec, M, Vlaiculescu, M, Hancu, N, Diaconu Sotropa, M, Lupu, S, Mateescu, A, Carlan, L, Marton, R, Lupusoru, D, Mot, A, Coman, A, Zaharie, D, Rebrov, A, Shutemova, E, 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Male ,medicine.medical_specialty ,dapagliflozin, placebo ,[SDV]Life Sciences [q-bio] ,Renal function ,Type 2 diabetes ,[SDV.BC]Life Sciences [q-bio]/Cellular Biology ,030204 cardiovascular system & hematology ,03 medical and health sciences ,chemistry.chemical_compound ,0302 clinical medicine ,Glucosides ,Diabetes mellitus ,Internal medicine ,medicine ,Humans ,030212 general & internal medicine ,Myocardial infarction ,Benzhydryl Compounds ,Dapagliflozin ,Sodium-Glucose Transporter 2 Inhibitors ,ComputingMilieux_MISCELLANEOUS ,Aged ,Heart Failure ,Canagliflozin ,business.industry ,[SDV.BA]Life Sciences [q-bio]/Animal biology ,General Medicine ,Middle Aged ,[SDV.SP]Life Sciences [q-bio]/Pharmaceutical sciences ,medicine.disease ,Hospitalization ,Diabetes Mellitus, Type 2 ,chemistry ,Cardiovascular Diseases ,Heart failure ,Cardiology ,Female ,business ,[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition ,Mace ,medicine.drug - Abstract
BACKGROUND The cardiovascular safety profile of dapagliflozin, a selective inhibitor of sodium-glucose cotransporter 2 that promotes glucosuria in patients with type 2 diabetes, is undefined. METHODS We randomly assigned patients with type 2 diabetes who had or were at risk for atherosclerotic cardiovascular disease to receive either dapagliflozin or placebo. The primary safety outcome was a composite of major adverse cardiovascular events (MACE), defined as cardiovascular death, myocardial infarction, or ischemic stroke. The primary efficacy outcomes were MACE and a composite of cardiovascular death or hospitalization for heart failure. Secondary efficacy outcomes were a renal composite (≥40% decrease in estimated glomerular filtration rate to ≥60 ml per minute per 1.73 m2 of body-surface area, new end-stage renal disease, or death from renal or cardiovascular causes) and death from any cause. RESULTS We evaluated 17,160 patients, including 10,186 without atherosclerotic cardiovascular disease, who were followed for a median of 4.2 years. In the primary safety outcome analysis, dapagliflozin met the prespecified criterion for noninferiority to placebo with respect to MACE (upper boundary of the 95% confidence interval [CI], ≥1.3; P≥0.001 for noninferiority). In the two primary efficacy analyses, dapagliflozin did not result in a lower rate of MACE (8.8% in the dapagliflozin group and 9.4% in the placebo group; hazard ratio, 0.93; 95% CI, 0.84 to 1.03; P = 0.17) but did result in a lower rate of cardiovascular death or hospitalization for heart failure (4.9% vs. 5.8%; hazard ratio, 0.83; 95% CI, 0.73 to 0.95; P = 0.005), which reflected a lower rate of hospitalization for heart failure (hazard ratio, 0.73; 95% CI, 0.61 to 0.88); there was no between-group difference in cardiovascular death (hazard ratio, 0.98; 95% CI, 0.82 to 1.17). A renal event occurred in 4.3% in the dapagliflozin group and in 5.6% in the placebo group (hazard ratio, 0.76; 95% CI, 0.67 to 0.87), and death from any cause occurred in 6.2% and 6.6%, respectively (hazard ratio, 0.93; 95% CI, 0.82 to 1.04). Diabetic ketoacidosis was more common with dapagliflozin than with placebo (0.3%vs. 0.1%, P = 0.02), as was the rate of genital infections that led to discontinuation of the regimen or that were considered to be serious adverse events (0.9% vs. 0.1%, P≥0.001). CONCLUSIONS In patients with type 2 diabetes who had or were at risk for atherosclerotic cardiovascular disease, treatment with dapagliflozin did not result in a higher or lower rate of MACE than placebo but did result in a lower rate of cardiovascular death or hospitalization for heart failure, a finding that reflects a lower rate of hospitalization for heart failure. (Funded by AstraZeneca; DECLARETIMI 58 ClinicalTrials.gov number, NCT01730534
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- 2019
40. Comparison of the performance of estimated fetal weight charts for the detection of small‐ and large‐for‐gestational age newborns with adverse outcomes: a French population‐based study.
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Monier, I, Ego, A, Benachi, A, Hocquette, A, Blondel, B, Goffinet, F, and Zeitlin, J
- Abstract
Objective: To compare the performance of estimated fetal weight (EFW) charts at the third trimester ultrasound for detecting small‐ and large‐for‐gestational age (SGA/LGA) newborns with adverse outcomes. Design: Nationally representative observational study. Setting: French maternity units in 2016. Population: 9940 singleton live births with an ultrasound between 30 and 35 weeks of gestation. Methods: We compared three prescriptive charts (INTERGROWTH‐21st, World Health Organization (WHO), Eunice Kennedy Shriver National Institute of Child Health and Human Development [NICHD]), four descriptive charts (Hadlock, Fetal Medicine Foundation, two French charts) and a French customised growth model (Epopé). Main outcome measures: SGA and LGA (birthweights <10th and >90th percentiles) associated with adverse outcomes (low Apgar score, delivery‐room resuscitation, neonatal unit admission). Results: 2.1% and 1.1% of infants had SGA and LGA and adverse outcomes, respectively. The sensitivity and specificity for detecting these infants with an EFW <10th and >90th percentile varied from 29–65% and 84–96% for descriptive charts versus 27–60% and 83–96% for prescriptive charts. WHO and French charts were closest to the EFW distribution, yielding a balance between sensitivity and specificity for SGA and LGA births. INTERGROWTH‐21st and Epopé had low sensitivity for SGA with high sensitivity for LGA. Areas under the receiving operator characteristics curve ranged from 0.62 to 0.74, showing low to moderate predictive ability, and diagnostic odds ratios varied from 7 to 16. Conclusion: Marked differences in the performance of descriptive as well as prescriptive EFW charts highlight the importance of evaluating them for their ability to detect high‐risk fetuses. Choice of growth chart strongly affected identification of high‐risk fetuses at the third trimester ultrasound. Choice of growth chart strongly affected identification of high‐risk fetuses at the third trimester ultrasound. Linked article This article is commented on by F Figueras, pp. 949 in this issue. To view this minicommentary visit https://doi.org/10.1111/1471-0528.17108. [ABSTRACT FROM AUTHOR]
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- 2022
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41. Preterm birth time trends in Europe: a study of 19 countries
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Zeitlin, J, Szamotulska, K, Drewniak, N, Mohangoo, A D, Chalmers, J, Sakkeus, L, Irgens, L, Gatt, M, Gissler, M, and Blondel, B
- Published
- 2013
- Full Text
- View/download PDF
42. SSM and the SRB accountability at European level: room for improvements?: Banking Union Scrutiny
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Zeitlin, J., Brito Bastos, F., Political Economy and Transnational Governance (PETGOV, AISSR, FMG), and ACELG (FdR)
- Abstract
The paper distinguishes two contrasting models of accountability, one based on principal-agent relations, which is backward-looking, the other a dynamic and forward-looking model. The paper argues that this second model of accountability is more appropriate for independent bodies like the ECB/SSM and the SRB, operating in technically complex, rapidly evolving environments under conditions of high uncertainty, where parliaments and other political authorities have very limited sanctioning powers. It then goes on to review the nature and effectiveness of three main forms of accountability as applied to these institutions – administrative, judicial, and political – together with the contribution of external review bodies, such as the European Court of Auditors and the European Ombudsman, to their accountability at European level. Following the dynamic, forward-looking approach advocated above, the paper argues that the best way to improve the accountability of the SSM and the SRB is to request the ECB/SSM and SRB to make the findings of their internal quality assurance and review bodies publicly available (subject to constraints on professional secrecy) and for the EP to use these findings to scrutinize and stimulate public debate about the operations and effectiveness of the two institutions.
- Published
- 2020
43. The European Union Beyond the Polycrisis?: Integration and politicization in an age of shifting cleavages
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Zeitlin, J., Nicoli, F., and Political Economy and Transnational Governance (PETGOV, AISSR, FMG)
- Abstract
The European Union beyond the Polycrisis? explores the political dynamics of multiple crises faced by the EU, both at European level and within the member states. In so doing, it provides a state-of-the-art overview of current research on the relationship between politicization and European integration. The book proposes that the EU’s multi-dimensional crisis can be seen as a multi-level ‘politics trap’, from which the Union is struggling to escape. The individual contributions analyze the mechanisms of this trap, its relationship to the multiple crises currently faced by the EU, and the strategies pursued by a plurality of actors (the Commission, the European Parliament, national governments) to cope with its constraints. Overall, the book suggests that comprehensive, ‘grand’ bargains are for the moment out of reach, although national and supranational actors can find ways of ‘relaxing’ the politics trap and in so doing perhaps lay the foundations for more ambitious future solutions. This book, dedicated to the exploration of the political dynamics of multiple, simultaneous crises, offers an empirical and theoretical assessment of the existing political constraints on European integration.
- Published
- 2020
44. Cohort profile : effective Perinatal Intensive Care in Europe (EPICE) very preterm birth cohort
- Author
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Zeitlin, J, Maier, RF, Cuttini, M, Aden, U, Boerch, K, Gadzinowski, J, Jarreau, P-H, Lebeer, J, Norman, M, Pedersen, P, Petrou, S, Pfeil, JM, Toome, L, van Heijst, A, van Reempts, P, Varendi, H, Barros, H, Groups, EPICE and SHIPS Research, Sarrechia, Iemke, EPICE Reseach Group, SHIPS Research Group, Equipe 1 : EPOPé - Épidémiologie Obstétricale, Périnatale et Pédiatrique (CRESS - U1153), Centre de Recherche Épidémiologie et Statistique Sorbonne Paris Cité (CRESS (U1153 / UMR_A_1125 / UMR_S_1153)), Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Conservatoire National des Arts et Métiers [CNAM] (CNAM), HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-HESAM Université - Communauté d'universités et d'établissements Hautes écoles Sorbonne Arts et métiers université (HESAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), DHU Risques Et Grossesse, Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Philipps Universität Marburg = Philipps University of Marburg, IRCCS Ospedale Pediatrico Bambino Gesù [Roma], Department of Women's and Children's Health [Stockholm, Sweden], Karolinska University Hospital [Stockholm], Copenhagen University Hospital Hvidovre [Hvidovre, Danemark], University of Copenhagen = Københavns Universitet (UCPH), Poznan University of Medical Sciences [Poland] (PUMS), Department of Primary & Interdisciplinary Care, Disability Studies [Antwerpen, Belgium] (Faculty of Medicine), University of Antwerp (UA), Department of Clinical Science, Intervention and Technology [Stockholm, Sweden], Karolinska Institutet [Stockholm], Aalborg University [Denmark] (AAU), Warwick Medical School, University of Warwick [Coventry], Nuffield Department of Primary Care Health Sciences, University of Oxford, University of Oxford, European Foundation for the Care of Newborn Infants [Munich, Germany] (EFCNI), Tallinn Children's Hospital [Tallinn, Estonia], University of Tartu, Radboud University Medical Center [Nijmegen], Antwerp University Hospital [Edegem] (UZA), Study Centre for Perinatal Epidemiology [Brussels, Belgium] (SCPE), Tartu University Hospital [Tartu, Estonia], Instituto de Saúde Pública da Universidade do Porto [Porto, Portugal] (ISPUP), Universidade do Porto = University of Porto, University of Leicester, EPICE and SHIPS Research Group: J Lebeer, P Van Reempts, E Bruneel, E Cloet, A Oostra, E Ortibus, I Sarrechia, K Boerch, L Huusom, P Pedersen, T Weber, L Toome, H Varendi, M Männamaa, P Y Ancel, A Burguet, P H Jarreau, V Pierrat, P Truffert, R F Maier, M Zemlin, B Misselwitz, S Schmidt, L Wohlers, M Cuttini, D Di Lallo, G Ancora, D Baronciani, V Carnielli, I Croci, G Faldella, F Ferrari, F Franco, G Gargano, A van Heijst, C Koopman-Esseboom, J Gadzinowski, J Mazela, A Montgomery, T Pikuła, H Barros, R Costa, L Mendes Graça, M do Céu Machado, C Rodrigues, T Rodrigues, U Aden, A K Edstedt Bonamy, M Norman, E S Draper, E M Boyle, A Fenton, S J Johnson, B N Manktelow, D W A Milligan, S Mader, N Thiele, J M Walz, S Petrou, J Zeitlin, M Bonet, C Bonnet, R El Raffei, A Piedvache, A V Seppanen, PHILIBERT, Marianne, Conservatoire National des Arts et Métiers [CNAM] (CNAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Conservatoire National des Arts et Métiers [CNAM] (CNAM)-Université Sorbonne Paris Cité (USPC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Centre National de la Recherche Scientifique (CNRS)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP), Philipps University of Marburg, University of Copenhagen = Københavns Universitet (KU), University of Oxford [Oxford], and Universidade do Porto
- Subjects
Critical Care ,[SDV]Life Sciences [q-bio] ,Infant, Newborn ,Healthcare improvement science Radboud Institute for Health Sciences [Radboudumc 18] ,Cohort Studies ,Europe ,[SDV] Life Sciences [q-bio] ,Perinatal Care ,Treatment Outcome ,Pregnancy ,Infant, Extremely Premature ,Humans ,Premature Birth ,Female ,Human medicine ,Cohort Profiles ,ComputingMilieux_MISCELLANEOUS - Abstract
Contains fulltext : 220753.pdf (Publisher’s version ) (Open Access)
- Published
- 2020
45. Producing valid statistics when legislation, culture, and medical practices differ for births at or before the threshold of survival: Report of a European workshop
- Author
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Smith, L. K. Blondel, B. Zeitlin, J. Haidinger, Gerald and Alexander, Sophie Kolarova, Rumyana Rodin, Urelija and Kyprianou, Theopisti Velebil, Petr Mortensen, Laust Sakkeus, Luule Gissler, Mika Blondel, Beatrice Heller, Guenther and Lack, Nicholas Antsaklis, Aris Berbik, Istvan Olafsdottir, Helga Sol Bonham, Sheelagh Cuttini, Marina Misins, Janis and Isakova, Jelena Wagener, Yolande Gatt, Miriam Nijhuis, Jan and Klungsoyr, Kari Szamotulska, Katarzyna Barros, Henrique and Horga, Mihai Cap, Jan Tul, Natasa Bolumar, Francisco and Gottvall, Karin Kallen, Karin Berrut, Sylvan Riggenbach, Melanie Macfarlane, Alison Zeitlin, Jennifer Delnord, Marie and Durox, Melanie Hindori-Mohangoo, Ashna Euro-Peristat Sci Comm
- Published
- 2020
46. Leren van Casuïstiek. een analyse van institutionele innovaties en ontwikkelmogelijkheden in het Utrechtse Jeugdstelsel
- Author
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Helderman, J.K., Zeitlin, J., and Sabel, C.F.
- Subjects
Institute for Management Research - Abstract
Contains fulltext : 215774.pdf (Publisher’s version ) (Open Access) 38 p.
- Published
- 2020
47. Postnatal Corticosteroids Policy for Very Preterm Infants and Bronchopulmonary Dysplasia
- Author
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Nuytten, A, Behal, H, Duhamel, A, Jarreau, PH, Torchin, H, Milligan, D, Maier, RF, Zemlin, M, Zeitlin, J, Truffert, P, EPICE Research Group, and Instituto de Saúde Pública da Universidade do Porto
- Subjects
Pediatrics ,medicine.medical_specialty ,EPICE cohort ,Gestational Age ,03 medical and health sciences ,0302 clinical medicine ,Case mix index ,Adrenal Cortex Hormones ,030225 pediatrics ,Intensive care ,mental disorders ,Medicine ,Humans ,Infant, Very Low Birth Weight ,030212 general & internal medicine ,Adverse effect ,Bronchopulmonary Dysplasia ,business.industry ,Infant, Newborn ,Gestational age ,Infant ,Odds ratio ,medicine.disease ,Bronchopulmonary dysplasia ,Confidence interval ,Policy ,Very preterm infants ,Pediatrics, Perinatology and Child Health ,Cohort ,business ,Infant, Premature ,Developmental Biology ,Postnatal corticosteroids - Abstract
Introduction: Postnatal corticosteroids (PNC) are effective for reducing bronchopulmonary dysplasia (BPD) in very preterm neonates but are associated with adverse effects including an increased risk of cerebral palsy. PNC use in Europe is heterogeneous across regions. This study aimed to assess whether European neonatal intensive care units (NICUs) with a low use of PNC or an explicit policy to reduce PNC use had higher risks of mortality or BPD. Methods: We included 3,126 infants in 105 NICUs born between 24 + 0 and 29 + 6 weeks’ gestational age in 19 regions in 11 countries in the EPICE cohort. First, we identified clusters of NICUs using hierarchical clustering based on PNC use and BPD prevalence and compared case mix and mortality between the clusters. Second, a multilevel analysis was performed to evaluate the association between a restrictive PNC policy and BPD occurrence. Results: There were 3 clusters of NICUs: 52 with low PNC use and a low BPD rate, 37 with low PNC use and a high BPD rate, and 16 with high PNC use and a medium BPD rate. Neonatal mortality did not differ between clusters (p = 0.88). A unit policy of restricted PNC use was not associated with a higher risk of BPD (odds ratio 0.68; 95% confidence interval: 0.45–1.03) after adjustment. Conclusion: Up to 49% of NICUs had low PNC use and low BPD rates, without a difference in mortality. Infants hospitalized in NICUs with a stated policy of low PNC use did not have an increased risk of BPD. The research leading to these results received funding from the European Union’s Seventh Framework Programme ([FP7/2007–2013]) under grant agreement No. 259882. We acknowledge additional funding from the following regions: France (French Institute of Public Health Research/Institute of Public Health and its partners the French Health Ministry, the National Institute of Health and Medical Research, the NationalInstitute of Cancer, and the National Solidarity Fund for Autonomy; grant ANR-11-EQPX-0038 from the National Research Agency through the French Equipex Program of Investments in the Future; and the PremUp Foundation); Poland (2012–2015 allocation of funds for international projects from the Polish Ministry of Science and Higher Education); Sweden (Stockholm County Council ALF-project and Clinical Research Appointment and the Department of Neonatal Medicine, Karolinska University Hospital); and the UK (the Neonatal Survey from Neonatal Networks for East Midlands and Yorkshire and Humber regions).
- Published
- 2020
48. Is Experimentalist Governance Self-Limiting or Self-Reinforcing? Strategic Uncertainty and Recursive Rulemaking in EU Electricity Regulation
- Author
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Rangoni, B., Zeitlin, J., and Political Economy and Transnational Governance (PETGOV, AISSR, FMG)
- Abstract
Is experimentalist governance (XG) self-limiting or self-reinforcing by virtue of its relationship to strategic uncertainty as an essential scope condition? This paper tackles this important but understudied question by elaborating a series of ideal-typical pathways for the temporal evolution of XG in specific policy domains, ranging from reversion to hierarchical governance through endogenous reduction of strategic uncertainty at one extreme to institutionalization of experimentalism as a multi-purpose governance architecture at the other. It then goes on to test the empirical validity of these contrasting theoretical expectations about the long-term relationship between XG and strategic uncertainty through a process-tracing analysis of electricity regulation in the European Union (EU) over a series of policy cycles since the 1990s. Building on and extending previous research in this domain, the paper shows how in a key problem area (cross-border network pricing) considered to exemplify reversion to hierarchical governance through endogenous reduction of strategic uncertainty, XG has in fact never withered away. In another key problem area (cross-border network access), the paper finds that, thanks to XG, policy actors came to identify successive solutions as nested inside one another, while never considering any one solution as definitive. Finally, the paper shows how policy actors, recognizing the pervasiveness of strategic uncertainty across the whole domain of electricity regulation, have come to institutionalize XG as a multi-purpose governance architecture. Following the Bayesian logic of theory-testing process tracing, the analysis thus strengthens empirical confidence in the theoretical expectation that XG is self-reinforcing, while diminishing confidence in the claim that it is self-limiting. The paper concludes by discussing how far these findings may travel to other policy fields within and beyond the EU.
- Published
- 2019
49. Courbes de poids à la naissance : une revue de la littérature
- Author
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Ego, A., Blondel, B., and Zeitlin, J.
- Published
- 2007
- Full Text
- View/download PDF
50. Introduction
- Author
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Moore, Scott H., Zeitlin, Jacob, and Petrarca, Francesco
- Published
- 2023
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