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11. Vigilanz

Author

Klösch, Gerhard, Hauschild, Peter, Zeitlhofer, Josef, Klösch, Gerhard, Hauschild, Peter, and Zeitlhofer, Josef

Published
2020
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14. The role of actigraphy in sleep medicine

Author

Acker, Jens G., Becker-Carus, C., Büttner-Teleaga, Antje, Cassel, Werner, Danker-Hopfe, Heidi, Dück, Alexander, Frohn, Corinna, Hein, Holger, Penzel, Thomas, Rodenbeck, Andrea, Roenneberg, Till, Sauter, Cornelia, Weeß, Hans-Günter, Zeitlhofer, Josef, and Richter, Kneginja

Published
2021
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16. The role of actigraphy in sleep medicine

Author

Acker, Jens G., Becker-Carus, C., Büttner-Teleaga, Antje, Cassel, Werner, Danker-Hopfe, Heidi, Dück, Alexander, Frohn, Corinna, Hein, Holger, Penzel, Thomas, Rodenbeck, Andrea, Roenneberg, Till, Sauter, Cornelia, Weeß, Hans-Günter, Zeitlhofer, Josef, and Richter, Kneginja

Abstract

Actigraphy has been used for more than 60 years to objectively measure sleep–wake rhythms. Improved modern devices are increasingly employed to diagnose sleep medicine disorders in the clinical setting. Although less accurate than polysomnography, the chief advantage of actigraphs lies in the cost-effective collection of objective data over prolonged periods of time under everyday conditions. Since the cost of wrist actigraphy is not currently reimbursed, this method has not enjoyed wide acceptance to date. The present article provides an overview of the main clinical applications of actigraphy, including the recommendations of specialist societies.

Published
2024
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18. Klinische Neurophysiologie

Author

Zeitlhofer, Josef, Moser, Doris C., Klösch, G., Lehrner, Johann, editor, Pusswald, Gisela, editor, Fertl, Elisabeth, editor, Strubreither, Wilhelm, editor, and Kryspin-Exner, Ilse, editor

Published
2011
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20. Klinische Neurophysiologie

Author

Zeitlhofer, Josef, Lehrner, Johann, editor, Pusswald, Gisela, editor, Fertl, Elisabeth, editor, Kryspin-Exner, Ilse, editor, and Strubreither, Wilhelm, editor

Published
2006
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24. Stellenwert der Aktigraphie in der schlafmedizinischen Versorgung

Author

Acker, Jens G., primary, Becker-Carus, C., additional, Büttner-Teleaga, Antje, additional, Cassel, Werner, additional, Danker-Hopfe, Heidi, additional, Dück, Alexander, additional, Frohn, Corinna, additional, Hein, Holger, additional, Penzel, Thomas, additional, Rodenbeck, Andrea, additional, Roenneberg, Till, additional, Sauter, Cornelia, additional, Weeß, Hans-Günter, additional, Zeitlhofer, Josef, additional, and Richter, Kneginja, additional

Published
2021
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35. Perception of sleep: subjective versus objective sleep parameters in patients with Parkinson's disease in comparison with healthy elderly controls; Sleep perception in Parkinson's disease and controls

Author

Happe, Svenja, Klosch, Gerhard, Lorenzo, Jose, Kunz, Dieter, Penzel, Thomas, Roschke, Joachim, Himanen, S.-L., Gruber, Georg, and Zeitlhofer, Josef

Subjects
Parkinson's disease -- Development and progression, Parkinson's disease -- Physiological aspects, Sleep disorders -- Research, Sleep disorders -- Causes of, Sleep disorders -- Diagnosis, Health
Published
2005

39. Sleep microstructure and neurodegeneration as measured by [[.sup.123]I][beta]-CIT SPECT in treated patients with Parkinson's disease

Author

Happe, Svenja, Anderer, Peter, Pirker, Walter, Klosch, Gerhard, Gruber, Georg, Saletu, Bernd, and Zeitlhofer, Josef

Subjects
SPECT imaging -- Usage, Sleep disorders -- Research, Parkinson's disease -- Complications and side effects, Parkinson's disease -- Research, Nervous system -- Degeneration, Nervous system -- Measurement, Health
Abstract

Byline: Svenja Happe (1,2), Peter Anderer (3), Walter Pirker (1), Gerhard Klosch (1), Georg Gruber (3), Bernd Saletu (3), Josef Zeitlhofer (1) Keywords: K-complex; sleep spindle; Parkinson's disease; SPECT; dopamine Abstract: Abstract Objectives Along with spindles, K-complexes are well known hallmarks of stage 2 (S2) sleep. However, little is known about their quantity in S2 sleep of patients with Parkinson's disease (PD). Setting Sleep laboratory, Department of Neurology, University of Vienna, Austria. Patients and methods Whole-night polysomnography (PSG) was performed in twelve treated PD patients and ten healthy controls without history of sleep complaints. The quantity of spontaneous K-complexes, K-alpha-complexes, and sleep spindles in one hour S2 sleep, distributed in four epochs of 15 minutes all through the night, were visually selected and analysed. The quantity and the temporal course of these phasic events were compared with the quantity in age-matched healthy controls. Nine of the twelve PD patients underwent [[.sup.123]I][beta]-CIT SPECT for calculating dopamine transporter binding in the striatum and serotonin transporter density in the thalamus-hypothalamus region. Results There was no difference between the quantity of K-complexes, K-alpha-complexes, and sleep spindles in PD patients and in the healthy control group. K-complexes but not sleep spindles decreased over the night in both groups. The number of sleep spindles did not correlate with the dopamine transporter binding in the striatum or the serotonin binding in the thalamic/hypothalamic region. Conclusion K-complexes and sleep spindles are not reduced and do not seem to be related to the degree of dopaminergic degeneration in treated PD patients. Author Affiliation: (1) Department of Neurology, University of Vienna, Austria (2) Department of Clinical Neurophysiology, University of Gottingen, Robert-Koch-Str. 40, 37099, Gottingen, Germany (3) Department of Psychiatry, University of Vienna, Austria Article History: Registration Date: 01/01/2004 Received Date: 09/02/2004 Accepted Date: 27/05/2004 Article note: This research was supported in part by the European Commission, DG XII (Project Biomed-2 BMH4-CT97--2040 'SIESTA') and by the Austrian National Bank (Project 7870). Svenja Happe, MD, was recipient for a fellowship stipend of the European Neurological Society (ENS).

Published
2004

46. Procedural memory consolidation is associated with heart rate variability and sleep spindles

Author

van Schalkwijk, Frank J., Hauser, Theresa, Hoedlmoser, Kerstin, Ameen, Mohamed S., Wilhelm, Frank H., Sauter, Cornelia, Klösch, Gerhard, Moser, Doris, Gruber, Georg, Anderer, Peter, Saletu, Bernd, Parapatics, Silvia, Zeitlhofer, Josef, and Schabus, Manuel

Subjects
Adult, Male, Polysomnography, HRV, motor skill adaptation, Sleep and Memory, Young Adult, Heart Rate, Humans, Female, Regular Research Paper, Sleep, spindles, mirror tracing, memory, Memory Consolidation
Abstract

Sleep and memory studies often focus on overnight rather than long‐term memory changes, traditionally associating overnight memory change (OMC) with sleep architecture and sleep patterns such as spindles. In addition, (para‐)sympathetic innervation has been associated with OMC after a daytime nap using heart rate variability (HRV). In this study we investigated overnight and long‐term performance changes for procedural memory and evaluated associations with sleep architecture, spindle activity (SpA) and HRV measures (R‐R interval [RRI], standard deviation of R‐R intervals [SDNN], as well as spectral power for low [LF] and high frequencies [HF]). All participants (N = 20, M age = 23.40 ± 2.78 years) were trained on a mirror‐tracing task and completed a control (normal vision) and learning (mirrored vision) condition. Performance was evaluated after training (R1), after a full‐night sleep (R2) and 7 days thereafter (R3). Overnight changes (R2‐R1) indicated significantly higher accuracy after sleep, whereas a significant long‐term (R3‐R2) improvement was only observed for tracing speed. Sleep architecture measures were not associated with OMC after correcting for multiple comparisons. However, individual SpA change from the control to the learning night indicated that only “SpA enhancers” exhibited overnight improvements for accuracy and long‐term improvements for speed. HRV analyses revealed that lower SDNN and LF power was associated with better OMC for the procedural speed measure. Altogether, this study indicates that overnight improvement for procedural memory is specific for spindle enhancers, and is associated with HRV during sleep following procedural learning.

Published
2019

47. Journal of Sleep Research / Procedural memory consolidation is associated with heart rate variability and sleep spindles

Author

van Schalkwijk, Frank J., Hauser, Theresa, Hoedlmoser, Kerstin, Ameen, Mohamed S., Wilhelm, Frank H., Sauter, Cornelia, Klösch, Gerhard, Moser, Doris, Gruber, Georg, Anderer, Peter, Saletu, Bernd, Parapatics, Silvia, Zeitlhofer, Josef, and Schabus, Manuel

Abstract

Sleep and memory studies often focus on overnight rather than longterm memory changes, traditionally associating overnight memory change (OMC) with sleep architecture and sleep patterns such as spindles. In addition, (para)sympathetic innervation has been associated with OMC after a daytime nap using heart rate variability (HRV). In this study we investigated overnight and longterm performance changes for procedural memory and evaluated associations with sleep architecture, spindle activity (SpA) and HRV measures (RR interval [RRI], standard deviation of RR intervals [SDNN], as well as spectral power for low [LF] and high frequencies [HF]). All participants (N = 20, Mage = 23.40 2.78 years) were trained on a mirrortracing task and completed a control (normal vision) and learning (mirrored vision) condition. Performance was evaluated after training (R1), after a fullnight sleep (R2) and 7 days thereafter (R3). Overnight changes (R2R1) indicated significantly higher accuracy after sleep, whereas a significant longterm (R3R2) improvement was only observed for tracing speed. Sleep architecture measures were not associated with OMC after correcting for multiple comparisons. However, individual SpA change from the control to the learning night indicated that only “SpA enhancers” exhibited overnight improvements for accuracy and longterm improvements for speed. HRV analyses revealed that lower SDNN and LF power was associated with better OMC for the procedural speed measure. Altogether, this study indicates that overnight improvement for procedural memory is specific for spindle enhancers, and is associated with HRV during sleep following procedural learning. P15370 W1233G17 (VLID)4373764

Published
2019

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