Search

Your search keyword '"Zechendorf, Elisabeth"' showing total 24 results
Start Over Author "Zechendorf, Elisabeth"
24 results on '"Zechendorf, Elisabeth"'

2. On the Use of Evolutionary Computation for In-Silico Medicine: Modelling Sepsis via Evolving Continuous Petri Nets

Author

Hallawa, Ahmed, Zechendorf, Elisabeth, Song, Yi, Schmeink, Anke, Peine, Arne, Marin, Lukas, Ascheid, Gerd, Dartmann, Guido, Hutchison, David, Editorial Board Member, Kanade, Takeo, Editorial Board Member, Kittler, Josef, Editorial Board Member, Kleinberg, Jon M., Editorial Board Member, Mattern, Friedemann, Editorial Board Member, Mitchell, John C., Editorial Board Member, Naor, Moni, Editorial Board Member, Pandu Rangan, C., Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Terzopoulos, Demetri, Editorial Board Member, Tygar, Doug, Editorial Board Member, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Kaufmann, Paul, editor, and Castillo, Pedro A., editor

Published
2019
Full Text
View/download PDF

7. The Potential Impact of Heparanase Activity and Endothelial Damage in COVID-19 Disease

Author

Zechendorf, Elisabeth, primary, Schröder, Katharina, additional, Stiehler, Lara, additional, Frank, Nadine, additional, Beckers, Christian, additional, Kraemer, Sandra, additional, Dreher, Michael, additional, Kersten, Alexander, additional, Thiemermann, Christoph, additional, Marx, Gernot, additional, Simon, Tim-Philipp, additional, and Martin, Lukas, additional

Published
2022
Full Text
View/download PDF

9. Inhibition of Macrophage Migration Inhibitory Factor Activity Attenuates Haemorrhagic Shock-Induced Multiple Organ Dysfunction in Rats

Author

Patel, Nikita M., primary, Yamada, Noriaki, additional, Oliveira, Filipe R. M. B., additional, Stiehler, Lara, additional, Zechendorf, Elisabeth, additional, Hinkelmann, Daniel, additional, Kraemer, Sandra, additional, Stoppe, Christian, additional, Collino, Massimo, additional, Collotta, Debora, additional, Alves, Gustavo Ferreira, additional, Ramos, Hanna Pillmann, additional, Sordi, Regina, additional, Marzi, Ingo, additional, Relja, Borna, additional, Marx, Gernot, additional, Martin, Lukas, additional, and Thiemermann, Christoph, additional

Published
2022
Full Text
View/download PDF

10. A Synthetic Peptide Designed to Neutralize Lipopolysaccharides Attenuates Metaflammation and Diet-Induced Metabolic Derangements in Mice

Author

Mohammad, Shireen, primary, Al Zoubi, Sura, additional, Collotta, Debora, additional, Krieg, Nadine, additional, Wissuwa, Bianka, additional, Ferreira Alves, Gustavo, additional, Purvis, Gareth S. D., additional, Norata, Giuseppe Danilo, additional, Baragetti, Andrea, additional, Catapano, Alberico Luigi, additional, Solito, Egle, additional, Zechendorf, Elisabeth, additional, Schürholz, Tobias, additional, Correa-Vargas, Wilmar, additional, Brandenburg, Klaus, additional, Coldewey, Sina M., additional, Collino, Massimo, additional, Yaqoob, Muhammad M., additional, Martin, Lukas, additional, and Thiemermann, Christoph, additional

Published
2021
Full Text
View/download PDF

12. The inhibition of Macrophage Migration Inhibitory Factor by ISO-1 attenuates trauma-induced multi organ dysfunction in rats

Author

Martin, Lukas, primary, Patel, Nikita Mayur, additional, Yamada, Noriaki, additional, Borges Oliveira, Filipe Rodolfo Moreira, additional, Stiehler, Lara, additional, Zechendorf, Elisabeth, additional, Hinkelmann, Daniel, additional, Kraemer, Sandra, additional, Stoppe, Christian, additional, Collino, Massimo, additional, Collotta, Debora, additional, Alves, Gustavo Ferreira, additional, Ramos, Hanna Pillmann, additional, Sordi, Regina, additional, Marzi, Ingo, additional, Relja, Borna, additional, Marx, Gernot, additional, and Thiemermann, Christoph, additional

Published
2021
Full Text
View/download PDF

13. Prognostic Value of Bioactive Adrenomedullin in Critically Ill Patients with COVID-19 in Germany: An Observational Cohort Study

Author

Simon, Tim-Philipp, primary, Stoppe, Christian, additional, Breuer, Thomas, additional, Stiehler, Lara, additional, Dreher, Michael, additional, Kersten, Alexander, additional, Kluge, Stefan, additional, Karakas, Mahir, additional, Zechendorf, Elisabeth, additional, Marx, Gernot, additional, and Martin, Lukas, additional

Published
2021
Full Text
View/download PDF

15. Corrigendum: Heparan Sulfate Induces Necroptosis in Murine Cardiomyocytes: A Medical-in-Silico Approach Combining Experiments and Machine Learning

Author

Zechendorf, Elisabeth, Vaßen, Phillip, Zhang, Jieyi, Hallawa, Ahmed, Martincuks, Antons, Krenkel, Oliver, Müller-Newen, Gerhard, Schuerholz, Tobias, Simon, Tim-Philipp, Marx, Gernot, Ascheid, Gerd, Schmeink, Anke, Dartmann, Guido, Thiemermann, Christoph, and Martin, Lukas Benjamin

Abstract

Frontiers in immunology 11, 630463 (2020). doi:10.3389/fimmu.2020.630463, Published by Frontiers Media, Lausanne

Published
2020
Full Text
View/download PDF

16. Corrigendum: Heparan Sulfate Induces Necroptosis in Murine Cardiomyocytes: A Medical-in-Silico Approach Combining In Vitro Experiments and Machine Learning

Author

Zechendorf, Elisabeth, primary, Vaßen, Phillip, additional, Zhang, Jieyi, additional, Hallawa, Ahmed, additional, Martincuks, Antons, additional, Krenkel, Oliver, additional, Müller-Newen, Gerhard, additional, Schuerholz, Tobias, additional, Simon, Tim-Philipp, additional, Marx, Gernot, additional, Ascheid, Gerd, additional, Schmeink, Anke, additional, Dartmann, Guido, additional, Thiemermann, Christoph, additional, and Martin, Lukas, additional

Published
2020
Full Text
View/download PDF

18. Ribonuclease 1 attenuates septic cardiomyopathy and cardiac apoptosis in a murine model of polymicrobial sepsis

Author

Zechendorf, Elisabeth, primary, O’Riordan, Caroline E., additional, Stiehler, Lara, additional, Wischmeyer, Natalie, additional, Chiazza, Fausto, additional, Collotta, Debora, additional, Denecke, Bernd, additional, Ernst, Sabrina, additional, Müller-Newen, Gerhard, additional, Coldewey, Sina M., additional, Wissuwa, Bianka, additional, Collino, Massimo, additional, Simon, Tim-Philipp, additional, Schuerholz, Tobias, additional, Stoppe, Christian, additional, Marx, Gernot, additional, Thiemermann, Christoph, additional, and Martin, Lukas, additional

Published
2020
Full Text
View/download PDF

19. Response

Author

Martin, Lukas, primary, Derwall, Matthias, additional, Al Zoubi, Sura, additional, Zechendorf, Elisabeth, additional, Reuter, Daniel A., additional, Thiemermann, Chris, additional, and Schuerholz, Tobias, additional

Published
2019
Full Text
View/download PDF

20. The Septic Heart

Author

Martin, Lukas, primary, Derwall, Matthias, additional, Al Zoubi, Sura, additional, Zechendorf, Elisabeth, additional, Reuter, Daniel A., additional, Thiemermann, Chris, additional, and Schuerholz, Tobias, additional

Published
2019
Full Text
View/download PDF

21. Heparan Sulfate Induces Necroptosis in Murine Cardiomyocytes: A Medical-In silico Approach Combining In vitro Experiments and Machine Learning

Author

Zechendorf, Elisabeth, primary, Vaßen, Phillip, additional, Zhang, Jieyi, additional, Hallawa, Ahmed, additional, Martincuks, Antons, additional, Krenkel, Oliver, additional, Müller-Newen, Gerhard, additional, Schuerholz, Tobias, additional, Simon, Tim-Philipp, additional, Marx, Gernot, additional, Ascheid, Gerd, additional, Schmeink, Anke, additional, Dartmann, Guido, additional, Thiemermann, Christoph, additional, and Martin, Lukas, additional

Published
2018
Full Text
View/download PDF

22. The Endothelial Glycocalyx: New Diagnostic and Therapeutic Approaches in Sepsis

Author

Martin, Lukas, Koczera, Patrick, Zechendorf, Elisabeth, and Schuerholz, Tobias

Subjects
Article Subject
Abstract

Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection. The endothelial glycocalyx is one of the earliest sites involved during sepsis. This fragile layer is a complex network of cell-bound proteoglycans, glycosaminoglycan side chains, and sialoproteins lining the luminal side of endothelial cells with a thickness of about 1 to 3 μm. Sepsis-associated alterations of its structure affect endothelial permeability and result in the liberation of endogenous damage-associated molecular patterns (DAMPs). Once liberated in the circulatory system, DAMPs trigger the devastating consequences of the proinflammatory cascades in sepsis and septic shock. In this way, the injury to the glycocalyx with the consecutive release of DAMPs contributes to a number of specific clinical effects of sepsis, including acute kidney injury, respiratory failure, and septic cardiomyopathy. Moreover, the extent of glycocalyx degradation serves as a marker of endothelial dysfunction and sepsis severity. In this review, we highlight the crucial role of the glycocalyx in sepsis as a diagnostic tool and discuss the potential of members of the endothelial glycocalyx serving as hopeful therapeutic targets in sepsis-associated multiple organ failures.

Published
2016
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results