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299 results on '"Zarei-Ghanavati, Siamak"'

1. Development, comparison, and internal validation of prediction models to determine the visual prognosis of patients with open globe injuries using machine learning approaches

Author

Shariati, Mehrdad Motamed, Eslami, Saeid, Shoeibi, Nasser, Eslampoor, Alireza, Sedaghat, Mohammadreza, Gharaei, Hamid, Zarei-Ghanavati, Siamak, Derakhshan, Akbar, Abrishami, Majid, Abrishami, Mojtaba, Hosseini, Seyedeh Maryam, Rad, Saeed Shokuhi, Astaneh, Mohammadreza Ansari, and Farimani, Raheleh Mahboub

Published
2024
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5. Optimized Artificial Intelligence for Enhanced Ectasia Detection Using Scheimpflug-Based Corneal Tomography and Biomechanical Data

Author

Ambrósio, Renato, Jr, Machado, Aydano P., Leão, Edileuza, Lyra, João Marcelo G., Salomão, Marcella Q., Esporcatte, Louise G. Pellegrino, da Fonseca Filho, João B.R., Ferreira-Meneses, Erica, Sena, Nelson B., Jr, Haddad, Jorge S., Costa Neto, Alexandre, de Almeida, Gildasio Castelo, Jr, Roberts, Cynthia J., Elsheikh, Ahmed, Vinciguerra, Riccardo, Vinciguerra, Paolo, Bühren, Jens, Kohnen, Thomas, Kezirian, Guy M., Hafezi, Farhad, Hafezi, Nikki L., Torres-Netto, Emilio A., Lu, Nanji, Kang, David Sung Yong, Kermani, Omid, Koh, Shizuka, Padmanabhan, Prema, Taneri, Suphi, Trattler, William, Gualdi, Luca, Salgado-Borges, José, Faria-Correia, Fernando, Flockerzi, Elias, Seitz, Berthold, Jhanji, Vishal, Chan, Tommy C.Y., Baptista, Pedro Manuel, Reinstein, Dan Z., Archer, Timothy J., Rocha, Karolinne M., Waring, George O., IV, Krueger, Ronald R., Dupps, William J., Khoramnia, Ramin, Hashemi, Hassan, Asgari, Soheila, Momeni-Moghaddam, Hamed, Zarei-Ghanavati, Siamak, Shetty, Rohit, Khamar, Pooja, Belin, Michael W., and Lopes, Bernardo T.

Published
2023
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9. Ocular Biometric and Optical Coherence Tomography Parameters in Former Preterm Children: A Cohort Study.

Author

Najjaran, Marzieh, Zarei-Ghanavati, Siamak, Ostadimoghaddam, Hadi, Yekta, Abbasali, Shoeibi, Nasser, Hemmati, Armin, Abrishami, Mojtaba, Akhlaghi, Saeed, Ziaei, Mohammed, and Cagini, Carlo

Subjects
*EYE, *OPTICAL coherence tomography, *PREMATURE infants, *BEVACIZUMAB, *BIOMETRY, *DESCRIPTIVE statistics, *RETROSPECTIVE studies, *LONGITUDINAL method, *MEDICAL records, *ACQUISITION of data, *GESTATIONAL age, *COMPARATIVE studies, *VISUAL acuity, *RETROLENTAL fibroplasia, *CHILDREN
Abstract

Purpose. To compare biometric and optical coherence tomography parameters as well as refractive status in preterm children aged 4–8 years with or without retinopathy of prematurity (ROP), and evaluate their correlations with age and gender‐matched full‐term children. Methods. Retrospective comparative cohort study of four groups of children. Children with a history of preterm birth, including ROP who received intravitreal bevacizumab (IVB) treatment, children with a history of ROP that regressed without treatment and those with no history of ROP were compared to age and gender‐matched full‐term children as a control group. Best corrected visual acuity (BCVA), spherical equivalent of refraction (SE), macular and choroidal thickness, as well as biometric parameters was measured. Results. A total of 120 eyes of 120 children (30 children in each group) were included. There was no significant difference in BCVA, SE, and subjective cylinder between groups (p = 0.05, p = 0.3, p = 0.6, respectively). Axial length was significantly shorter, and the cornea was steeper in both ROP groups than in other groups (p = 0.001, p < 0.001, respectively). The central macular thickness was significantly thicker in the treated, regressed ROP and preterm groups than in full‐term children (p < 0.001). The gestational age was negatively correlated with macular thickness in both treated and regressed ROP groups (r = −0.517; p = 0.003, r = − 0.490; p = 0.006, respectively). Conclusions. Children with a history of ROP had a shorter axial length, steeper cornea, and thicker macula that correlated with lower gestational age. [ABSTRACT FROM AUTHOR]

Published
2024
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19. Corneal Patching

Author

Bamdad, Shahram, Azimi, Ali, Zarei-Ghanavati, Siamak, Schmidt-Erfurth, Ursula, editor, and Kohnen, Thomas, editor

Published
2018
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21. Syphilis: Overview

Author

Bamdad, Shahram, bagheri, Mansooreh, Zarei-Ghanavati, Siamak, Schmidt-Erfurth, Ursula, editor, and Kohnen, Thomas, editor

Published
2018
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25. Keratin 13 is a more specific marker of conjunctival epithelium than keratin 19.

Author

Ramirez-Miranda, Arturo, Nakatsu, Martin N, Zarei-Ghanavati, Siamak, Nguyen, Christine V, and Deng, Sophie X

Subjects
Eye Disease and Disorders of Vision, Eye, Adult, Biomarkers, Child, Preschool, Conjunctiva, Cornea, Epithelial Cells, Epithelium, Gene Expression, Gene Expression Profiling, Humans, Immunohistochemistry, Keratin-12, Keratin-13, Keratin-19, Middle Aged, Oligonucleotide Array Sequence Analysis, RNA, Messenger, Opthalmology and Optometry, Ophthalmology & Optometry
Abstract

PurposeTo evaluate the expression patterns of cytokeratin (K) 12, 13, and 19 in normal epithelium of the human ocular surface to determine whether K13 could be used as a marker for conjunctival epithelium.MethodsTotal RNA was isolated from the human conjunctiva and central cornea. Those transcripts that had threefolds or higher expression levels in the conjunctiva than the cornea were identified using microarray technique. Expression levels of three known signature genes and of two conjunctival genes, K13 and K19 were confirmed by using quantitative real-time PCR (qRT-PCR). Protein expression of K12, K13, and K19 was confirmed by immunostaining with specific antibodies on histologic sections of human sclerocornea that contained the conjunctiva, limbus, and cornea and on impression cytology (IC) specimens of the cornea and conjunctiva from normal donors. Double staining of K13/K12 and K19/K12 on histologic sections and IC specimens was performed.ResultsThere were 337 transcripts that were preferentially expressed in the conjunctiva. K13 and K19 were among the top twenty transcripts in the conjunctiva and this preferential expression pattern of K13 and K19 was confirmed by qRT-PCR. Immunohistochemical studies showed that K13 was expressed at the posterior limbal epithelium and conjunctival epithelium but was totally absent in the cornea. K12 was expressed in the corneal and anterior limbal epithelia except for the basal layer and was absent from the conjunctiva. In contrast, K19 was detected in the corneal, limbal and conjunctival epithelia. Immunostaining of the IC specimens showed K12(+) epithelial cells in the corneal region, K13(+) cells in the conjunctival area, and K19(+) cells in the corneal and conjunctival specimens. Expression of K13 and K12 on the ocular surface was mutually exclusive on both the histologic and IC samples using double immunostaining.ConclusionsK13 is more specific to the conjunctival epithelial cells than K19 and potentially could be used as a marker to identify conjunctival epithelial cells in limbal stem cell deficiency.

Published
2011

27. The burden and predisposing factors of non-communicable diseases in Mashhad University of Medical Sciences personnel: a prospective 15-year organizational cohort study protocol and baseline assessment

Author

Tohidinezhad, Fariba, Khorsand, Ali, Zakavi, Seyed Rasoul, Rezvani, Reza, Zarei-Ghanavati, Siamak, Abrishami, Majid, Moradi, Ali, Tavakoli, Mahmoud, Farrokh, Donya, Rad, Masoud Pezeshki, Abbasi, Bita, Ahadi, Mitra, Saleh, Lahya Afshari, Tayebi, Mohammad, Amini, Mahnaz, Poustchi, Hossein, Abu-Hanna, Ameen, and Eslami, Saeid

Published
2020
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31. Trachoma

Author

Zarei-Ghanavati, Siamak, Eslampoor, Alireza, Abrishami, Mojtaba, Deng, Sophie X., Hotez, Peter, Series editor, McDowell, Mary Ann, editor, and Rafati, Sima, editor

Published
2014
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32. Melanosis

Author

Ghafourian, Abdolhossein, Zarei-Ghanavati, Siamak, Schmidt-Erfurth, Ursula, editor, and Kohnen, Thomas, editor

Published
2018
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37. Effect of oral vitamin D supplementation on dry eye disease patients with vitamin D deficiency.

Author

Najjaran, Marzieh, Zarei- Ghanavati, Siamak, Arjmand Askari, Ehsan, Eslampoor, Alireza, and Ziaei, Mohammed

Subjects
*VITAMIN D deficiency, *DRY eye syndromes, *DIETARY supplements, *VITAMIN D, *ARTIFICIAL eyes, *OPTICAL goods stores
Abstract

Dry eye disease (DED) and vitamin D deficiency are both common clinical entities. Vitamin D has been reported to play a significant role in ocular surface homeostasis. This study aimed to determine the therapeutic effect of oral vitamin D supplementation in dry eye disease patients with vitamin D deficiency. A randomized, controlled study was completed in 100 patients with dry eye disease and concurrent vitamin D deficiency (< 20 ng/ml). Participants were randomly allocated to 8 weeks of oral vitamin D supplementation with both groups receiving conventional dry eye treatment with artificial tears. Schirmer's, tear break-up time (TBUT) and osmolarity tests were measured before and after eight weeks of treatment. The mean age of participants was 36.8 ± 8.56 years in the treatment group (n: 50) and 34.8 ± 10.13 year in the control group (n: 50). After eight weeks of treatment the mean differences in Schirmer's, TBUT and tear osmolarity were 2.38 ± 1.55 mm, 3.95 ± 1.48 s and −16.9 ± 6.28 mOsm/L, respectively in the treatment group, and 0.7 ± 0.86 mm, 0.92 ± 1.57s and −3.34 ± 2.0 mOsm/L respectively in the control group (p < 0.001 for all parameters). The treatment group demonstrated a more significant improvement than the control group in Schirmer's, TBUT and osmolarity values (p < 0.001). Vitamin D supplementation as an adjuvant to routine dry eye treatment improves ocular surface hemostasis parameters, results in better tear stability and a more improved tear osmolarity in patients with vitamin D deficiency. [ABSTRACT FROM AUTHOR]

Published
2023
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50. Melanosis

Author

Ghafourian, Abdolhossein, primary and Zarei-Ghanavati, Siamak, additional

Published
2014
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