7 results on '"Zappone, L."'
Search Results
2. Study on psychoeducation enhancing results of adherence in patients with schizophrenia (SPERA-S): study protocol for a randomized controlled trial
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Petretto, Dr, Preti, A, Zuddas, C, Veltro, F, Rocchi, Mb, Sisti, D, Martinelli, V, Carta, Mg, Masala, C, Alfa, Rita, Arcidiacono, E, Aguglia, E, Bonanni, E, Borea, M, Consolazione, M, De Giglio, P, DI ROSA, Antonio, Faravelli, C, Fioravanti, G, Fiori Nastro, P, Floris, A, Floris, F, Iannone, C, Iuso, S, La Verde, M, Laffranchini, L, Lecca, Me, Sauro, Cl, Magni, Lr, Margari, F, Marras, M, Marzano, L, Masotti, E, Matta, C, Minutolo, G, Moro, Mf, Mura, G, Nardini, M, Nicchiniello, I, Padalino, F, Papini, Mn, Pastore, A, Petito, A, Pioli, R, Porfiri, Gm, Pullara, A, Sancassiani, F, Seu, Mi, Stallone, V, Vinci, S, and Zappone, L.
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Research design ,Health Knowledge, Attitudes, Practice ,Time Factors ,medicine.medical_treatment ,Medicine (miscellaneous) ,Adherence to pharmacotherapy ,Caregiver ,Falloon's method ,Family ,Psychoeducation ,Randomized controlled trial ,Schizophrenia ,law.invention ,Study Protocol ,Clinical Protocols ,Cost of Illness ,Recurrence ,law ,Surveys and Questionnaires ,Pharmacology (medical) ,Chromatography, High Pressure Liquid ,Intention to Treat Analysis ,Treatment Outcome ,Caregivers ,Italy ,Research Design ,Schizophrenic Psychology ,Family Relations ,Drug Monitoring ,Psychosocial ,Antipsychotic Agents ,medicine.medical_specialty ,Blinding ,Medication Adherence ,Pharmacotherapy ,Patient Education as Topic ,schizophrenia ,Psychological adjustment ,caregivers ,medicine ,Humans ,Psychiatry ,Psychiatric Status Rating Scales ,Intention-to-treat analysis ,business.industry ,Falloon’s method ,Supportive psychotherapy ,Physical therapy ,Feasibility Studies ,business - Abstract
Poor adherence to pharmacotherapy negatively affects the course and the outcome of schizophreniaspectrum psychoses, enhancing the risk of relapse. Falloon and coworkers developed a Psychoeducation Program aimed at improving communication and problem-solving abilities in patients and their families. This study set out to evaluate changes in adherence to pharmacotherapy in patients diagnosed with schizophrenia-spectrum psychoses, by comparing one group exposed to the Falloon Psychoeducation Program (FPP) with another group exposed to family supportive therapy with generic information on the disorders. 340 patients diagnosed with schizophrenia and related disorders according to standardized criteria from 10 participating units distributed throughout the Italian National Health System (NHS), will be enrolled with 1:1 allocation by the method of blocks of randomized permutations. Patients will be reassessed at 6, 12 and 18 months after start of treatment (duration: 6 months). The primary objective is to evaluate changes in adherence to pharmacotherapy after psychoeducation. Adherence will be assessed at three-month intervals by measuring blood levels of the primary prescribed drug using high pressure liquid chromatography, and via the Medication Adherence Questionnaire and a modified version of the Adherence Interview. Secondary objectives are changes in the frequency of relapse and readmission, as the main indicator of the course of the disorder. Enrolled patients will be allocated to the FPP (yes/no) randomly, 1:1, in a procedure controlled by the coordinating unit; codes will be masked until the conclusion of the protocol (or the occurrence of a severe negative event). The raters will be blind to treatment allocation and will be tested for blinding after treatment completion. Intention-to-treat will be applied in considering the primary and secondary outcomes. Multiple imputations will be applied to integrate the missing data. The study started recruitment in February 2013; the total duration of the study is 27 months. If the psychoeducation program proves effective in improving adherence to pharmacotherapy and in reducing relapse and readmissions, its application could be proposed as a standard adjunctive psychosocial treatment within the Italian NHS. Protocol Registration System of ClinicalTrials.gov NCT01433094 ; registered on 20 August 2011; first patient was randomized on 12 February 2013.
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3. Functioning Management and Recovery, a psychoeducational intervention for psychiatric residential facilities: a multicenter follow-up study.
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Veltro F, Latte G, Pontarelli C, Barcella M, Silveri L, Cardone G, Nicchiniello I, Pontarelli I, Zappone L, Luso S, and Leggero P
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- Humans, Male, Female, Follow-Up Studies, Adult, Italy, Middle Aged, Residential Facilities, Patient Education as Topic methods, Schizophrenia therapy, Treatment Outcome, Psychotic Disorders therapy, Psychotic Disorders psychology
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Aim: Functional Management and Recovery is a standardized Psychoeducational Intervention, derived from "Integro", an effective salutogenic-psychoeducational intervention for people in recovery journey, designed to improve recovery and functioning of individuals with psychotic disorders in Psychiatric Residential Facilities (PRFs). The aim of this study is to evaluate the primary and secondary outcomes of this intervention elaborated specifically for PRFs where evidence based structured interventions seem rare and desirable., Methods: 66 individuals with psychotic disorders were recruited in 9 PRFs dislocated in the North, Center and South Italy and 63 underwent a multicenter follow-up study with a two time-point evaluation (t0, pre-treatment and t1, 6 months; ). At each time point, social functioning was assessed as primary outcome by the Personal and Social Performance scale (PSP); furthermore, psychopathological status was assessed by Brief Psychiatric Rating Scale (BPRS), Recovery by Recovery Assessment Scale (RAS), Cognitive Functioning by Repeatable Battery for the Assessment of Neuropsychological Status (RBANS), Stress management by Stress-Scale, Cognitive Flexibility by Modified Five-Point Test (M-FPT), Emotional Intelligence by Emotional Intelligence Index (EI-I), the PRF Atmosphere and the Opinion of users about the PFR by an ad hoc questionnaire. The Abilities Knowledge, the Utility and Pleasantness of sessions were measured by an ad hoc list of items., Results: 63 individuals out of 66, 52 (82,5%) affected by schizophrenia and 11 (17,5%) by bipolar I disorder with psychotic symptoms according to DSM-5-TR completed the study. At the end of the study, 43 (68,3%) were male, 57 (90.5%) were single, 5 (7.9%) engaged, 1 (1.6%) married; 45 (71.4%) unemployed. The total scores of PSP, RAS, BPRS, BANS, Stress management, Abilities Knowledge, Utility and Pleasantness of sessions showed a statistically significant improvement at t1 vs. t0. Two sub-scales out of 5 of M-FPT showed a statistically significant improvement. The Emotional Intelligence, the Unit Atmosphere and the Opinion of Users about PFR improved without statistical significance. Six months after the end of the follow-up study 22 individuals of the sample were dismissed with a very high turnover., Conclusions: After a six-month follow-up (a short period of time), these results showed improvement in functioning, the primary outcome, as well as in the following secondary outcome variables: RAS, BPRS, BANS, Stress management, Abilities Knowledge, two sub-scales out of 5 of M-FPT, Utility and Pleasantness of sessions. Overall, a remarkable impact of psychoeducational structured intervention on the key Recovery variables is observed. Further studies are needed to address extent and duration of these improvements., (© 2024. The Author(s).)
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- 2024
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4. Evaluation of a psychoeducational intervention adapted from the Falloon model for first episode psychosis: a one-year follow-up real-world study.
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Veltro F, Pontarelli I, Latte G, Pontarelli C, Nicchiniello I, and Zappone L
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- Male, Female, Humans, Follow-Up Studies, Psychotherapy, Recurrence, Psychotic Disorders psychology, Schizophrenia drug therapy
- Abstract
Aim: To evaluate the effectiveness of the Falloon Psychoeducational Family Intervention (PFI), originally developed for the management of schizophrenia, afterwards adapted for early psychosis, in terms of adherence to the treatment, low relapse rate, improvement social functioning and stress management., Methods: This is a one-year, pragmatic, real-world observational study with subjects consecutively recruited at the Campobasso psychiatry ward (SPDC) or Mental Health Center (MHC) starting in November 2020 over an 18 month period. Patients recruited were asked for consent for family members' participation. The effectiveness of the intervention was evaluated in terms of treatment adherence, discontinuity, relapse rates, clinical symptoms assessed by BPRS and PANSS, improvement in social functioning and stress management., Results: 13 subjects were recruited; 10 males and 3 females, all singles, with a DUP inferior to one year. At the end of the intervention, significant improvements in treatment adherence, absence of drop-outs and relapses, statistically significant improvements in clinical symptoms, social functioning and stress management were found., Discussion and Conclusions: The results clearly show that family psychoeducational intervention according to the adapted Falloon model, specifically focused on crisis and early stress management, is effective in improving treatment adherence, clinical outcome and social life of first-episode psychotic patients. The limit is the lack of a control and randomization.
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- 2024
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5. Positive impact of InteGRO, a new salutogenic psychoeducational intervention, in managing covid-19 pandemic and lockdown aftermath.
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Veltro F, Latte G, Pontarelli I, Pontarelli C, Nicchiniello I, and Zappone L
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- Communicable Disease Control, Humans, Pandemics prevention & control, Stress, Psychological therapy, COVID-19 epidemiology, Mental Disorders epidemiology, Mental Disorders therapy
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Aim: The covid-19 pandemic/lockdown had a great impact on Severe Mental Illnesses (SMI) on the following variables: adherence to protective measures, infection, Covid-related psychopathology, stress related symptoms exacerbation, social relationship loss and higher mortality risk. InteGRO, a new effective salutogenic-psychoeducational approach, has been designed to help people with SMI manage their life-stress and achieve personal recovery goals through improved social functioning. Positive outcomes after pandemic/lockdown in patients trained with InteGRO and also their opinion about its usefulness are discussed., Methods: All above mentioned variables were collected in a 1-year observational study (March 2020-2021) for all patients trained with InteGRO. In April 2021 patients were asked to respond to: an ad hoc semi-structured in-depth telephone interview, the Stress-Scale, the Brief Psychiatric Rating-Scale, the Personal and Social Performance Scale., Results: 37 people out of 41 underwent the observational study. The overall outcome was good: one patient with asymptomatic infection, 40/41 vaccinated, a very low (2/37) trend of hospital admissions similar to previous years, very high personal and social functioning as well as low level of stress. In the interview, patients answered they found the InteGRO Training very useful, above all the meetings concerning Defining Goal and Problem-Solving. They often felt their desire to socialize was prompted by InteGRO training., Conclusions: These results suggest InteGRO had a good impact on SMI patients to face pandemic/lockdown, with high level of personal and social functioning. They also suggest using structured salutogenic psychoeducational programs in public health services can be useful to promote life-skills to face traumatic events. Further studies are needed to understand the duration of these improvements and outcomes.
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- 2022
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6. Long term outcome study of a salutogenic psychoeducational recovery oriented intervention (Inte.G.R.O.) in severe mental illness patients.
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Veltro F, Latte G, Pontarelli I, Pontarelli C, Nicchiniello I, and Zappone L
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- Humans, Outcome Assessment, Health Care, Psychotherapy, Social Adjustment, Mental Disorders therapy, Sense of Coherence
- Abstract
Aim: Inte.G.R.O. is a standardized Salutogenic-Psychoeducational intervention designed to help people with severe mental illness manage their life-stress and achieve personal recovery goals through the improvement of social functioning. The aim of this study is to evaluate the long-term outcome of this approach, characterized by health promotion rather than correction of dysfunctional strategies., Methods: 41 people underwent an observational study with a three time-point evaluation (t0, pre- treatment; t1, 12 months; t2, 36 months). At each time point, social functioning was assessed as primary outcome by the Personal and Social Functioning scale (PSP); furthermore, psychopathological status was assessed by Brief Psychiatric Rating Scale (BPRS), stress management was measured by means of Stress-Scale and cognitive flexibility variables were assessed by Modified Five-Point Test (M-FPT)., Results: Personal and Social Functioning increased at t1 and t2 vs t0; psychopathological status improved at t2 vs t0; stress management improved at t2 vs t1; cognitive flexibility improved at t2 vs t0., Conclusions: these results substantially confirm after a three-year follow-up the improvements in functioning, psychopathology, stress management and cognitive flexibility seen in previous studies. Furthermore, they show a complex time-dependent fashion. Overall, they confirm a remarkable and long-term impact of Inte.G.R.O. on key Recovery variables. Further studies are needed to address extent and duration of these improvements., (© 2022. The Author(s).)
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- 2022
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7. Description and impact of a structured psychoeducational and salutogenetic approach (InteGRO) to support the recovery of people with severe mental disorders
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Veltro F, Nicchiniello I, Pica A, Pontarelli I, Iannone C, Pontarelli C, Zappone L, and Vendittelli N
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- Adult, Female, Goals, Health Services Needs and Demand, Hope, Humans, Male, Middle Aged, Neuropsychological Tests, Program Evaluation, Psychiatric Rehabilitation organization & administration, Self Efficacy, Social Adjustment, Stress, Psychological, Bipolar Disorder rehabilitation, Psychiatric Rehabilitation methods, Schizophrenia rehabilitation
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Aim: In mental health services there is an increasing attention to the recovery of people with severe mental illness. Consequently there is a growing literature on this topic focused above-all on the description of excellence paths that often include variables related to the organizational aspects of the service. Less attention is given to specific interventions to foster all the goals that are essential to improve the living conditions, including defining and planning goal, emotional perception, effective communication for negotiation, practical interpersonal and intrapersonal problem-solving. The aim of this paper is to describe an innovative and salutogenetic approach and to illustrate the results of the impact after a year of “active intervention”., Methods: We used a “quasi-experiment” design-study with a pre-post assessment without a control group on 21 subjects with schizophrenia or bipolar disorder according to DSM-IV-TR criteria. We used to evaluate Functioning, the primary outcome, the Personal and Social Performance Scale. For the secondary outcome measures we used the Stress-Scale, the Modified Five-Point Test for cognitive flexibility, the APEN/G e APEP/G Scale for perceived self-efficacy, the Integrative Hope Scale, the items “subjective and objective load” of the “Aid received, Needs and Burden” self-filled questionnaire. The clinical assessment was made by the Brief Psychyatric Rating Scale, while we used the Repeatable Battery for the Assessment of Neuropsychological Status., Results: Of the 21 subjects included, 18 completed the assessment. Significant improvements were noted for all variables considered, with particular relevance for Personal and Social Functioning (p<0.001). Predictive variables for this dimension were the level of stress and perceived self-efficacy (p<0.05)., Conclusions: The observed data confirm the effectiveness of this innovative approach, above all on Personal and Social Functioning where there has been improvement from two or more marked dysfunction areas to one area.
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- 2018
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