334 results on '"Zanlungo, Silvana"'
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2. Understanding the phenotypic variability in Niemann-Pick disease type C (NPC): a need for precision medicine
3. Identification of genetic modifiers of murine hepatic β-glucocerebrosidase activity
4. Lack of Annexin A6 Exacerbates Liver Dysfunction and Reduces Lifespan of Niemann-Pick Type C Protein–Deficient Mice
5. Exploring the lutein therapeutic potential in steatotic liver disease: mechanistic insights and future directions.
6. c-Abl Inhibition Activates TFEB and Promotes Cellular Clearance in a Lysosomal Disorder
7. Lysosome motility and distribution: Relevance in health and disease
8. c-Abl Phosphorylates MFN2 to Regulate Mitochondrial Morphology in Cells under Endoplasmic Reticulum and Oxidative Stress, Impacting Cell Survival and Neurodegeneration
9. MLN64 induces mitochondrial dysfunction associated with increased mitochondrial cholesterol content
10. Mitochondrial GSH replenishment as a potential therapeutic approach for Niemann Pick type C disease
11. c-Abl tyrosine kinase down-regulation as target for memory improvement in Alzheimer’s disease
12. Neuronal gene repression in Niemann–Pick type C models is mediated by the c-Abl/HDAC2 signaling pathway
13. Transgenic overexpression of Niemann-Pick C2 protein promotes cholesterol gallstone formation in mice
14. A Mouse Systems Genetics Approach Reveals Common and Uncommon Genetic Modifiers of Hepatic Lysosomal Enzyme Activities and Glycosphingolipids
15. c-Abl kinase at the crossroads of healthy synaptic remodeling and synaptic dysfunction in neurodegenerative diseases
16. Recent insights on the role of cholesterol in non-alcoholic fatty liver disease
17. A mouse systems genetics approach reveals common and uncommon genetic modifiers of hepatic lysosomal enzyme activities and glycosphingolipids
18. Autophagy Induced by Toll-like Receptor Ligands Regulates Antigen Extraction and Presentation by B Cells
19. Editorial: Cell compartments and intracellular trafficking of lipids and proteins: Impact on biomedicine
20. c-Abl Stabilizes HDAC2 Levels by Tyrosine Phosphorylation Repressing Neuronal Gene Expression in Alzheimer’s Disease
21. Neuronopathic Gaucher disease: Beyond lysosomal dysfunction
22. Lysosomal vitamin E accumulation in Niemann–Pick type C disease
23. Oxidative stress activates the c-Abl/p73 proapoptotic pathway in Niemann-Pick type C neurons
24. c-Abl Activation Linked to Autophagy-Lysosomal Dysfunction Contributes to Neurological Impairment in Niemann-Pick Type A Disease
25. Cell compartments and intracellular trafficking of lipids and proteins: Impact on biomedicine
26. c-Abl kinase at the crossroads of healthy synaptic remodeling and synaptic dysfunction in neurodegenerative diseases.
27. Alterations in Lysosome Homeostasis in Lipid-Related Disorders: Impact on Metabolic Tissues and Immune Cells
28. Proteomic Analysis of Niemann-Pick Type C Hepatocytes Reveals Potential Therapeutic Targets for Liver Damage
29. Increased copper levels in in vitro and in vivo models of Niemann-Pick C disease
30. Niemann-Pick C2 Protein Expression Regulates Lithogenic Diet-Induced Gallstone Formation and Dietary Cholesterol Metabolism in Mice
31. Genistein Activates Transcription Factor EB and Corrects Niemann–Pick C Phenotype
32. P450 CYP2C epoxygenase and CYP4A ω-hydroxylase mediate ciprofibrate-induced PPARα-dependent peroxisomal proliferation
33. Role of plasma and liver cholesterol- and lipoprotein-metabolism determinants in LpX formation in the mouse
34. Increased NPC1 and STARD3 expression in placentas from women with Maternal Supraphysiological Hypercholesterolemia (MSPH) promotes lysosomal and mitochondrial dysfunction.
35. Inactivation of Hepatic Microsomal Triglyceride Transfer Protein Protects Mice From Diet-Induced Gallstones
36. Overexpression of MLN64 in hepatic cells induces mitochondrial dysfunction associated with increased transport of cholesterol into mitochondria: 1248
37. Mitochondrial GSH resplenishment prevents progressive liver injury and extends life span in Niemann Pick Disease type C: 748
38. Abnormalities of lipid metabolism, gallstone disease and gallbladder function
39. Apolipoprotein A-I deficiency does not affect biliary lipid secretion and gallstone formation in mice
40. Cholecystectomy increases hepatic triglyceride content and very-low-density lipoproteins production in mice
41. Complement Component C3 Participates in Early Stages of Niemann–Pick C Mouse Liver Damage
42. ABL1 kinase inhibitors for the treatment of Niemann-Pick disease type A
43. c-Abl Inhibition Activates TFEB: A Novel Way To Promote Cellular Clearance in Lysosomal Disorders
44. Deficiency of Niemann-Pick C1 protein protects against diet-induced gallstone formation in mice
45. Determinants of transhepatic cholesterol flux and their relevance for gallstone formation
46. Insulin and cholesterol gallstones: New insights for a complex pathogenic relationship
47. The rpl5-rps 14-cob gene arrangement in Solanum tuberosum: rps14 is a transcribed and unedited pseudogene
48. Reply
49. Adenovirus-mediated hepatic syndecan-1 overexpression induces hepatocyte proliferation and hyperlipidaemia in mice
50. Increased activity of hepatic microsomal triglyceride transfer protein and bile acid synthesis in gallstone disease
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