424 results on '"Zanivan, Sara"'
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2. Leukaemia exposure alters the transcriptional profile and function of BCR::ABL1 negative macrophages in the bone marrow niche
3. Mitochondrial DNA mutations drive aerobic glycolysis to enhance checkpoint blockade response in melanoma
4. Mitochondrial outer membrane integrity regulates a ubiquitin-dependent and NF-κB-mediated inflammatory response
5. eIF4A1-dependent mRNAs employ purine-rich 5’UTR sequences to activate localised eIF4A1-unwinding through eIF4A1-multimerisation to facilitate translation
6. Editorial Expression of Concern: Class 3 semaphorins control vascular morphogenesis by inhibiting integrin function
7. A palmitate-rich metastatic niche enables metastasis growth via p65 acetylation resulting in pro-metastatic NF-κB signaling
8. PTEN deficiency exposes a requirement for an ARF GTPase module for integrin‐dependent invasion in ovarian cancer
9. Omentum-derived matrix enables the study of metastatic ovarian cancer and stromal cell functions in a physiologically relevant environment
10. Proline metabolism shapes the tumor microenvironment: from collagen deposition to immune evasion
11. Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix
12. MASTL is enriched in cancerous and pluripotent stem cells and influences OCT1/OCT4 levels
13. Neuropilin 1 and its inhibitory ligand mini-tryptophanyl-tRNA synthetase inversely regulate VE-cadherin turnover and vascular permeability
14. Metabolic pathways fuelling protumourigenic cancer-associated fibroblast functions
15. Metabolic adaptations of micrometastases alter EV production to generate invasive microenvironments
16. CYRI-B loss promotes enlarged mature focal adhesions and restricts microtubule and ERC1 access to the cell leading edge
17. Quantitative proteomics identifies the core proteome of exosomes with syntenin-1 as the highest abundant protein and a putative universal biomarker
18. E3 ligase-inactivation rewires CBL interactome to elicit oncogenesis by hijacking RTK–CBL–CIN85 axis
19. THEM6‐mediated reprogramming of lipid metabolism supports treatment resistance in prostate cancer
20. Translation of secretory mRNAs must be restrained during early oncogenesis to permit hepatocellular carcinoma initiation
21. STIM1 translocation to the nucleus protects cells from DNA damage
22. Nuclear-capture of endosomes depletes nuclear G-actin to promote SRF/MRTF activation and cancer cell invasion
23. Ultraviolet light-induced collagen degradation inhibits melanoma invasion
24. An ARF GTPase module promoting invasion and metastasis through regulating phosphoinositide metabolism
25. BRF1 accelerates prostate tumourigenesis and perturbs immune infiltration
26. Methylmalonic acid: an age-related metabolite that drives tumour aggressiveness
27. Author Correction: Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix
28. Cancer-associated fibroblasts produce matrix-bound vesicles that influence endothelial cell function.
29. The helminth TGF-beta mimic TGM4 is a modular ligand that binds CD44, CD49d and TGF-beta receptors to preferentially target myeloid cells
30. Engineered immunomodulatory extracellular vesicles derived from epithelial cells acquire capacity for positive and negative T cell co-stimulation in cancer and autoimmunity
31. Mutant p53 promotes RCP-dependent chemoresistance coinciding with increased delivery of P-glycoprotein to the plasma membrane
32. The eIF4A2 negative regulator of mRNA translation promotes extracellular matrix deposition to accelerate hepatocellular carcinoma initiation
33. Phosphodiesterase 2A2 regulates mitochondria clearance through Parkin-dependent mitophagy
34. The conversion of formate into purines stimulates mTORC1 leading to CAD-dependent activation of pyrimidine synthesis
35. 2,4-dienoyl-CoA reductase regulates lipid homeostasis in treatment-resistant prostate cancer
36. Formate induces a metabolic switch in nucleotide and energy metabolism
37. eIF4A2 drives repression of translation at initiation by Ccr4-Not through purine-rich motifs in the 5′UTR
38. Fam49/CYRI interacts with Rac1 and locally suppresses protrusions
39. Supplementary Methods from Colorectal Tumors Require NUAK1 for Protection from Oxidative Stress
40. Supplementary Table 3 from Colorectal Tumors Require NUAK1 for Protection from Oxidative Stress
41. Data from Colorectal Tumors Require NUAK1 for Protection from Oxidative Stress
42. Figures S1-S6 & Tables S1 & S2 from Colorectal Tumors Require NUAK1 for Protection from Oxidative Stress
43. Data from SLFN5 Regulates LAT1-Mediated mTOR Activation in Castration-Resistant Prostate Cancer
44. Supplementary Data 2 from SLFN5 Regulates LAT1-Mediated mTOR Activation in Castration-Resistant Prostate Cancer
45. Supplementary Information from SLFN5 Regulates LAT1-Mediated mTOR Activation in Castration-Resistant Prostate Cancer
46. Integrated Proteomics Unveils Nuclear PDE3A2 as a Regulator of Cardiac Myocyte Hypertrophy
47. Tumour mitochondrial DNA mutations drive aerobic glycolysis to enhance checkpoint blockade
48. Author Reply to Peer Reviews of PTEN deficiency exposes a requirement for an ARF GTPase module in integrin-dependent invasion in ovarian cancer.
49. Bicarbonate transport as regulator of antitumour immunity in pancreatic cancer
50. Integrated Proteomics Unveils Nuclear PDE3A2 as a Regulator of Cardiac Myocyte Hypertrophy
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