584 results on '"Zanger, Ulrich M."'
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2. Regulation of drug metabolism and toxicity by multiple factors of genetics, epigenetics, lncRNAs, gut microbiota, and diseases: a meeting report of the 21st International Symposium on Microsomes and Drug Oxidations (MDO).
3. In silico and biological analyses of missense variants of the human biliary efflux transporter ABCC2: effects of novel rare missense variants.
4. Differential effects on human cytochromes P450 by CRISPR/Cas9-induced genetic knockout of cytochrome P450 reductase and cytochrome b5 in HepaRG cells
5. Correction to: Progesterone receptor membrane component 1 regulates lipid homeostasis and drives oncogenic signaling resulting in breast cancer progression
6. Copy number variation profiling in pharmacogenes using panel-based exome resequencing and correlation to human liver expression
7. The azole fungicide tebuconazole affects human CYP1A1 and CYP1A2 expression by an aryl hydrocarbon receptor-dependent pathway
8. Unnatural Endotype B PPAPs as Novel Compounds with Activity against Mycobacterium tuberculosis
9. P450 Monooxygenase System
10. Progesterone receptor membrane component 1 regulates lipid homeostasis and drives oncogenic signaling resulting in breast cancer progression
11. The formation of estrogen-like tamoxifen metabolites and their influence on enzyme activity and gene expression of ADME genes
12. Rifampin enhances cytochrome P450 (CYP) 2B6-mediated efavirenz 8-hydroxylation in healthy volunteers
13. Inflammatory regulation of steroid sulfatase: A novel mechanism to control estrogen homeostasis and inflammation in chronic liver disease
14. Clinical relevance of DPYD variants c.1679T>G, c.1236G>A/HapB3, and c.1601G>A as predictors of severe fluoropyrimidine-associated toxicity: a systematic review and meta-analysis of individual patient data
15. Methyleugenol DNA adducts in human liver are associated with SULT1A1 copy number variations and expression levels
16. Association between CYP2E1 polymorphisms and risk of differentiated thyroid carcinoma
17. P450 Mono-oxygenase System
18. Pregnane X receptor activation and silencing promote steatosis of human hepatic cells by distinct lipogenic mechanisms
19. Effect of CYP2B6*6 and CYP2C19*2 genotype on chlorpyrifos metabolism
20. Effect of CYP2B6, ABCB1, and CYP3A5 Polymorphisms on Efavirenz Pharmacokinetics and Treatment Response: An AIDS Clinical Trials Group Study
21. Effects of Diminished NADPH:cytochrome P450 Reductase in Human Hepatocytes on Lipid and Bile Acid Homeostasis
22. Role of ABC Transporters in Fluoropyrimidine-Based Chemotherapy Response
23. Antibodies against Human Cytochrome P-450db1 in Autoimmune Hepatitis Type II
24. Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation
25. Functional study of the 830C>G polymorphism of the human carboxylesterase 2 gene
26. Non-synonymous polymorphisms in the human SLCO1B1 gene: an in vitro analysis of SNP c.1929A>C
27. Additional file 1 of Progesterone receptor membrane component 1 regulates lipid homeostasis and drives oncogenic signaling resulting in breast cancer progression
28. GSTP1 and MDR1 Genotypes and Central Nervous System Relapse in Childhood Acute Lymphoblastic Leukemia
29. Limited contribution of CYP3A5 to the hepatic 6β-hydroxylation of testosterone
30. Cytochrome P450 2D6: overview and update on pharmacology, genetics, biochemistry
31. Polycyclic Aromatic Hydrocarbons Activate the Aryl Hydrocarbon Receptor and the Constitutive Androstane Receptor to Regulate Xenobiotic Metabolism in Human Liver Cells
32. Tri‐Allelic Haplotypes Determine and Differentiate Functionally Normal Allele CYP2D6*2 and Impaired Allele CYP2D6*41
33. Thiopurine methyltransferase (TPMT) genotype and early treatment response to mercaptopurine in childhood acute lymphoblastic leukemia
34. Cardiovascular Drugs
35. Importance of Pharmacogenomics
36. ABCC11/MRP8 polymorphisms affect 5-fluorouracil-induced severe toxicity and hepatic expression
37. Abundance of DNA adducts of methyleugenol, a rodent hepatocarcinogen, in human liver samples
38. Novel CYP2B6 Enzyme Variants in a Rwandese Population: Functional Characterization and Assessment of In Silico Prediction Tools
39. Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation
40. Distribution of Microsomal Epoxide Hydrolase in Humans: An Immunohistochemical Study in Normal Tissues, and Benign and Malignant Tumours
41. PPARA: A Novel Genetic Determinant of CYP3A4 In Vitro and In Vivo
42. Immunohistochemical Detection of Microsomal Epoxide Hydrolase in Human Synovial Tissue
43. Chapter 8. The CYP2D Subfamily
44. Inferring statin-induced gene regulatory relationships in primary human hepatocytes
45. TGF-β2 silencing to target biliary-derived liver diseases
46. MiR-155 and other microRNAs downregulate drug metabolizing cytochromes P450 in inflammation
47. Copy number variation profiling in pharmacogenes using panel-based exome resequencing and correlation to human liver expression
48. Expression of Organic Cation Transporters OCT1 (SLC22A1) and OCT3 (SLC22A3) Is Affected by Genetic Factors and Cholestasis in Human Liver†
49. Pharmacogenomics of human liver cytochrome P450 oxidoreductase: multifactorial analysis and impact on microsomal drug oxidation
50. 6-Mercaptopurine and 9-(2-Phosphonyl- Methoxyethyl) Adenine (PMEA) Transport Altered by Two Missense Mutations in the Drug Transporter Gene ABCC4
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