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Aims: Early prenatal diagnosis of congenital heart disease is feasible. Conventional autopsy is the current gold standard method for post-mortem confirmation. Radiologic techniques alternative to conventional autopsy, such as post-mortem micro-computed tomography, have been proposed in case of limited diagnostic accuracy (i.e., early termination of pregnancy, samples of small dimension or of low weight). The aim of the present study was to define accuracy of micro-computed tomography for post-mortem diagnosis of congenital heart disease in gross anatomy samples. Methods and Results: Fetal heart underwent in-utero prenatal echocardiography and ex-vivo post-mortem evaluation by 9 μm resolution micro-computed tomography and conventional autopsy. For each case, 25 indices of cardiac anatomy were studied by post-mortem micro-computed tomography and conventional autopsy; these were used to compare the two post mortem techniques. Ten samples were examined (gestational age between 12 + 4 and 21 + 6 weeks of gestation). Considering comparable indices, agreement between post-mortem micro-computed tomography and conventional autopsy was of 100% and sensitivity and specificity were of 100%. In "challenging specimens," post-mortem micro-computed tomography diagnoses more indices as compared to conventional autopsy and 84% of "not-diagnostic" indices at conventional autopsy would be diagnostic at post-mortem micro-computed tomography. Conclusion: Micro-computed tomography can be a valid diagnostic alternative to conventional autopsy for post-mortem evaluation of human fetal heart. In addition, it may prove superior to conventional autopsy particularly in cases coming from early termination of pregnancy or in samples of small dimension or of low weight.

Double-outlet left ventricle is an exceedingly rare congenital heart defect. Its prenatal detection and precise anatomical definition are challenging for a variety of reasons and have never been previously reported. Here described are 2 cases of prenatally diagnosed double-outlet left ventricle. The technical limitations of prenatal diagnosis and its implications for the surgical management of patients affected by such a rare condition are discussed.

To assess how hysterectomy was psychologically overcome we refer to the results obtained from a questionnaire given to 40 patients. The questionnaire was divided into 3 parts: one statistic-epidemiologic, one to evaluate the patients' level of information, and a third aimed at studying post-operative psychological and sexual adaptability.

In our research we have evaluated the effects produced by obstetric psycho-prophylaxis on women previously prepared by us. To carry out this research we used a method of pain evaluation, quickly and easily administered: Vaona algometer, based on the association between the visual analogue and the scale of greys. The results of the research allow us to confirm that the RAT method, applied during labour, thanks to the positive influence on neuromuscolar relaxation and the psychological aspects of the women, induces a favourable modulation on the perception of pain.

Twenty patients who had undergone hysterectomy were given a questionnaire consisting of three parts, the first statistical and epidemiological, the second aimed at assessing the extent to which the patient was informed about her condition and a third part designed to provide data on postoperative adaptation. The good results obtained are discussed and interpreted.