851 results on '"Zampella, Angela"'
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2. Development of dual GPBAR1 agonist and RORγt inverse agonist for the treatment of inflammatory bowel diseases
3. Bile acids and bile acid activated receptors in the treatment of Covid-19
4. Immunology of bile acids regulated receptors
5. Combinatorial therapy with BAR502 and UDCA resets FXR and GPBAR1 signaling and reverses liver histopathology in a model of NASH
6. Bile acids serve as endogenous antagonists of the Leukemia inhibitory factor (LIF) receptor in oncogenesis
7. Activation of GPBAR1 attenuates vascular inflammation and atherosclerosis in a mouse model of NAFLD-related cardiovascular disease
8. Development of bile acid activated receptors hybrid molecules for the treatment of inflammatory and metabolic disorders
9. Thiazolidin-4-one-based compounds interfere with the eicosanoid biosynthesis pathways by mPGES-1/sEH/5-LO multi-target inhibition
10. Design, Synthesis, and Pharmacological Evaluation of Dual FXR-LIFR Modulators for the Treatment of Liver Fibrosis.
11. Sex and gender specific pitfalls and challenges in cardiac rehabilitation: a working hypothesis towards better inclusivity in cardiac rehabilitation programmes.
12. A microbial derived bile acid acts as GPBAR1 agonist and RORγt inverse agonist and reverses inflammation in inflammatory bowel disease
13. Inverse Virtual Screening for the rapid re-evaluation of the presumed biological safe profile of natural products. The case of steviol from Stevia rebaudiana glycosides on farnesoid X receptor (FXR)
14. BAR502/fibrate conjugates: synthesis, biological evaluation and metabolic profile.
15. Chemistry and Pharmacology of GPBAR1 and FXR Selective Agonists, Dual Agonists, and Antagonists
16. Bile acid-activated receptors and the regulation of macrophages function in metabolic disorders
17. Defective Bile Acid Signaling Promotes Vascular Dysfunction, Supporting a Role for G‐Protein Bile Acid Receptor 1/Farnesoid X Receptor Agonism and Statins in the Treatment of Nonalcoholic Fatty Liver Disease
18. Bile acids and bile acid activated receptors in the treatment of Covid-19
19. GPBAR1 Functions as Gatekeeper for Liver NKT Cells and provides Counterregulatory Signals in Mouse Models of Immune-Mediated Hepatitis
20. Correction to “Discovery of a Novel Class of Dual GPBAR1 Agonists–RORγt Inverse Agonists for the Treatment of IL-17-Mediated Disorders”
21. The leukemia inhibitory factor regulates fibroblast growth factor receptor 4 transcription in gastric cancer
22. Bile Acids Serve As Endogenous Antagonists Of The Leukemia Inhibitory Factor (LIF) Receptor in Oncogenesis
23. Chemistry and Pharmacology of GPBAR1 and FXR Selective Agonists, Dual Agonists, and Antagonists
24. Theonella: A Treasure Trove of Structurally Unique and Biologically Active Sterols
25. Discovery of BAR502, as potent steroidal antagonist of leukemia inhibitory factor receptor for the treatment of pancreatic adenocarcinoma
26. Discovery of ((1,2,4-oxadiazol-5-yl)pyrrolidin-3-yl)ureidyl derivatives as selective non-steroidal agonists of the G-protein coupled bile acid receptor-1
27. Beneficial effects of UDCA and norUDCA in a rodent model of steatosis are linked to modulation of GPBAR1/FXR signaling
28. Discovery of a Novel Class of Dual GPBAR1 Agonists–RORγt Inverse Agonists for the Treatment of IL-17-Mediated Disorders
29. Molecular decodification of gymnemic acids from Gymnema sylvestre. Discovery of a new class of liver X receptor antagonists
30. Modeling inflammatory bowel disease by intestinal organoids
31. Repositioning Mifepristone as a Leukaemia Inhibitory Factor Receptor Antagonist for the Treatment of Pancreatic Adenocarcinoma
32. Combinatorial targeting of G‐protein‐coupled bile acid receptor 1 and cysteinyl leukotriene receptor 1 reveals a mechanistic role for bile acids and leukotrienes in drug‐induced liver injury
33. Insights on pregnane-X-receptor modulation. Natural and semisynthetic steroids from Theonella marine sponges
34. Combinatorial targeting of G‐protein‐coupled bile acid receptor 1 and cysteinyl leukotriene receptor 1 reveals a mechanistic role for bile acids and leukotrienes in drug‐induced liver injury.
35. Immunomodulatory functions of FXR
36. Next-Generation Sequencing Analysis of Gastric Cancer Identifies the Leukemia Inhibitory Factor Receptor as a Driving Factor in Gastric Cancer Progression and as a Predictor of Poor Prognosis
37. Isoswinholide B and swinholide K, potently cytotoxic dimeric macrolides from Theonella swinhoei
38. Characterisation of the dynamic interactions between complex N-glycans and human CD22
39. New antimalarial polyketide endoperoxides from the marine sponge Plakinastrella mamillaris collected at Fiji Islands
40. Gracilioethers E–J, new oxygenated polyketides from the marine sponge Plakinastrella mamillaris
41. Expanding the Library of 1,2,4-Oxadiazole Derivatives: Discovery of New Farnesoid X Receptor (FXR) Antagonists/Pregnane X Receptor (PXR) Agonists.
42. Anti-inflammatory cyclopeptides from the marine sponge Theonella swinhoei
43. Next generation sequencing analysis of gastric cancer identifies the leukemia inhibitory factor receptor (LIFR) as a driving factor in gastric cancer progression and as a predictor of poor prognosis
44. Tu1111: REGULATION OF INTESTINAL ACE2 EXPRESSION BY THE BILE ACID RECEPTOR GPBAR1 IS MEDIATED BY A GPBAR1/GLP-1/GLP-1R AXIS
45. Mo1353: DEVELOPMENT OF A DUAL GPBAR1 AND CYSTLTR1 MODULATOR TO PREVENT HEPATIC DAMAGE AND LIVER FIBROSIS
46. Tu1304: ROLE OF A DUAL GPBAR1/CYSLT1R MODULATOR REVERSES LIVER INJURY AND FIBROSIS IN A RODENT MODEL OF NASH
47. Sa1541: DISCOVERY OF A NOVEL CYSTEINYL-LEUKOTRIENE-RECEPTOR 1 ANTAGONIST AND BILE ACID RECEPTOR GPBAR1 AGONIST THAT REDUCES INFLAMMATION IN A MOUSE MODEL OF COLITIS
48. Discovery of a Potent and Orally Active Dual GPBAR1/CysLT1R Modulator for the Treatment of Metabolic Fatty Liver Disease
49. Modeling Inflammatory Bowel Disease by Intestinal Organoids
50. GLP-1 Mediates Regulation of Colonic ACE2 Expression by the Bile Acid Receptor GPBAR1 in Inflammation
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