Search

Background. Biliopancreatic tumors (BPT) are among the most aggressive solid malignancies, and their incidence is rising. Good patient outcome relies heavily on a multidisciplinary approach to therapy, including timely access to endoscopy, surgery and chemo/radiotherapy. We aimed to evaluate current practices as reflected in the management and outcome of patients diagnosed with BPT in the setting of a low-resource medical system in order to identify areas suitable for improvement.

Copyright of Farmacia is the property of Societatea de Stiinte Farmaceutice Romania and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Anorectal melanoma (ARM) is an extremely rare and aggressive malignancy. There is no standard therapeutic management, mainly due to scarcity of data and randomized control trials regarding the optimal surgical strategy. We present the case of a male patient aged 65 years in our hospital, presenting perineal pain and rectal bleeding. Patient's performance status (PS) was good. Hematological analysis revealed normocytic normochromic anemia. In the rectoscopy, an anal canal tumor formation was identified. The diagnosis of ulcerated melanoma was confirmed at the histopathological examination. The pelvic MRI detected a circumferential parietal thickening, posteriorly accentuated at the level of the anal canal, about 4.4 cm long, situated 2 cm from the external anal orifice, causing a subtotal lumen stenosis. The patient underwent abdominoperineal resection (APR). Postoperative course was favorable and the patient was discharged on the 13th postoperative day, with no complications. A multidisciplinary cancer care team will prove to be of substantial value, because it may develop a personalized treatment plan for this unusual tumor. Although the therapeutic approach is still controversial, surgery is considered the mainstay therapy. [ABSTRACT FROM AUTHOR]