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2. Pembrolizumab plus concurrent chemoradiotherapy versus placebo plus concurrent chemoradiotherapy in patients with locally advanced squamous cell carcinoma of the head and neck (KEYNOTE-412): a randomised, double-blind, phase 3 trial

Author

Rischin, Danny, Hughes, Brett GM, Gao, Bo, McGrath, Margaret, Greil, Richard, Thurnher, Dietmar, Fuereder, Thorsten, Burian, Martin, Rottey, Sylvie, Machiels, Jean-Pascal, Clement, Paul M, Henry, Stéphanie, Deheneffe, Stéphanie, Vasconcelos Alves, Gustavo, Lima, Iane Pinto Figueiredo, Mourão Dias, Josiane, De Marchi, Pedro Rafael Martins, Mak, Milena Perez, Pereira de Santana Gomes, Andrea Juliana, Oliveira de Castro Junior, Dalvaro, Motta, Tatiane Cardoso, Agostinho Padoan, Monica Luciana, Victorina, Ana Paula, de Azevedo, Sergio Jobim, Siu, Lillian L, Brule, Stephanie, Hilton, John, Wang, Chang Shu, Bouganim, Nathaniel, Webster, Marc, Walker, John, Chua, Neil, Zambrano, Angela Regina, Quiroga Echeverri, Alicia, Niño Gomez, Oscar Mauricio, Ortiz, Carlos Alberto, Rojas, Luis, Cardona Zorilla, Andrés, Urrego Meléndez, Olga Marcela, Holečková, Petra Beran, Melichar, Bohuslav, Cvek, Jakub, Prausová, Jana, Vošmik, Milan, Delord, Jean-Pierre, Zasadny, Xavier, Geoffrois, Lionnel, Tao, Yungan, Pointreau, Yoann, Fietkau, Rainer, Haderlein, Marlen, Mueller, Andreas H, Schroeder, Ursula, Wollenberg, Barbara, Laban, Simon, Ivanyi, Philipp, Gruenwald, Viktor, Schafhausen, Philippe, Gutfeld, Orit, Gluck, Iris, Popovtzer, Aron, Meirovitz, Amichay, Billan, Salem, Brenner, Baruch, Limon, Dror, Licitra, Lisa, Perri, Francesco, Caponigro, Francesco, Violati, Martina, Ferrari, Daris, Nole, Franco, Bertolini, Federica, Livi, Lorenzo, Ghi, Maria Grazia, Imarisio, Ilaria, Tahara, Makoto, Homma, Akihiro, Ueda, Tsutomu, Asada, Yukinori, Yamazaki, Tomoko, Matsumoto, Koji, Fujii, Takashi, Ikeda, Sadakatsu, Takahashi, Shunji, Kinoshita, Takashi, Sasaki, Keita, Tsuji, Akihito, Ahn, Myung-Ju, Cho, Byoung Chul, Lee, Keun-Wook, Lee, Ki Hyeong, Choi, Moon Ki, Yun, Hwan Jung, Hendriks, Mathijs P, Oosting, Sjoukje F, Buter, Jan, Van Meerten, Esther, Graham, Jonathan, Kawecki, Andrzej, Debicka, Izabella, Maciejczyk, Adam, Pysz, Maciej, Filarska, Dorota, Hetnał, Marcin, Koralewski, Piotr, Wygoda, Andrzej, Składowski, Krzysztof, Talerczyk, Małgorzata, Berrocal Jaime, Alfonso, Pérez Segura, Pedro, Braña García, Irene, Basté Rotllan, Neus, Mesía Nin, Ricard, Taberna Sanz, Miren, Iglesias Docampo, Lara, Soria Rivas, Ainara, Rueda Domínguez, Antonio, Trigo Pérez, José Manuel, Hong, Ruey-Long, Li, Shau-Hsuan, Wang, Hung-Ming, Yen, Chia-Jui, Yang, Muh-Hwa, Chang, Yi-Fang, Liu, Yi-Chun, Lin, Jin-Ching, Ekenel, Meltem, Harputluoğlu, Hakan, Aksoy, Sercan, Özyilkan, Özgür, Bılıcı, Ahmet, Şendur, Mehmet Alı Nahıt, Arslan, Cagatay, Harrington, Kevin, Ramkumar, Shanmugasundaram, Gujral, Dorothy, Stewart, Simon, Powell, Melanie, Sibtain, Amen, Roques, Tom, Yip, Kent, Mirza, Arafat, Sivaramalingam, Muthiah, Belman, Neil D, Agarwala, Sanjiv, Anderson, Ian, Patel, Arpan, Maggiore, Ronald, Baumgart, Megan, Burtness, Barbara, Fidler, Mary Jo, Kaur, Varinder, Gaughan, Elizabeth, Worden, Francis, Rodriguez, Cristina P, Sukari, Ammar, Wong, Deborah, Yom, Sue, Walsh, William V, Fiorillo, Joseph A, Yorio, Jeffrey T, Obara, Grzegorz S, Alves, Gustavo, Hughes, Brett G M, Mesía, Ricard, Taberna, Miren, Waldron, John N, Simon, Christian, Grégoire, Vincent, Harrington, Kevin J, Swaby, Ramona F, Zhang, Yayan, Gumuscu, Burak, and Bidadi, Behzad

Published
2024
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3. Lenvatinib plus pembrolizumab versus lenvatinib plus placebo for advanced hepatocellular carcinoma (LEAP-002): a randomised, double-blind, phase 3 trial

Author

Strasser, Simone, Thompson, Alexander, Roohullah, Aflah, Sievert, William, Andelkovic, Vladimir, Knox, Jennifer, Davies, Janine, Asselah, Jamil, Brahmania, Mayur, Majeed, Habeeb, Villanueva, Luis, Yanez Weber, Patricio, Garrido, Marcelo, Pizarro, Gonzalo Ignacio, Yanez, Nicolas, Xu, Ruocai, Ou, Shuangyan, Ren, Zhenggang, Pan, Hongming, Meng, Zhiqiang, Gu, Kangsheng, Chen, Xi, Zhang, Tao, Hao, Chunyi, Cao, Peiguo, Guo, Yabing, Qin, Shukui, Xiao, Juxiang, Fang, Weijia, Wang, Xin, Bai, Yuxian, Chen, Xiaoming, Yan, Dong, Zhao, Hong, Ying, Jieer, Bonilla, Carlos, Urrego, Olga, Zambrano, Angela, Lema, Mauricio, Restrepo Gutierrez, Juan Carlos, Cardona, Andres, Franco Millan, Sandra, Oscar, Madiedo, Ramos, Victor, Merle, Philippe, LeSourd, Samuel, Edeline, Julien, Bronowicki, Jean-Pierre, Bourliere, Marc, Cattan, Stephane, Bouattour, Mohamed, Mineur, Laurent, Regnault, Helene, Dauvois, Barbara, Schulze, Kornelius, Folprecht, Gunnar, Geier, Andreas, Waidmann, Oliver, Finkelmeier, Fabian, Venerito, Marino, Berres, Marie-Luise, Berg, Thomas, Lange, Christian, Schmidt, Hartmut, Waldschmidt, Dirk T, Bitzer, Michael, McDermott, Ray, Duffy, Austin, Masi, Gianluca, Zagonel, Vittorina, Tonini, Giuseppe, Piscaglia, Fabio, Gori, Stefania, Rizzo, Mimma, Biscaldi, Elisa, Foltran, Luisa, Cabibbo, Giuseppe, Ikeda, Masafumi, Kudo, Masatoshi, Aikata, Hiroshi, Numata, Kazushi, Marusawa, Hiroyuki, Kato, Naoya, Kurosaki, Masayuki, Morimoto, Manabu, Yamashita, Tatsuya, Koga, Hironori, Masaki, Tsutomu, Tateishi, Ryosuke, Inaba, Yoshitaka, Arakawa, Tomohiro, Suzuki, Yoshiyuki, Akua, Norio, Kobayashi, Masahiro, Hosaka, Tetsuya, Nakamuta, Makoto, Oza, Noriko, Kondo, Shunsuke, Furuse, Junji, Nagashima, Fumio, Kitano, Masayuki, Takaguchi, Koichi, Ryoo, Baek-Yeol, Lim, Ho Yeong, Kim, Jee Hyun, Kim, Tae-You, Kim, Han Sang, Hernandez Hernandez, Carlos, Motola Kuba, Daniel, Segura Gonzalez, Manuel, Cabrera Luviano, Jesus, Huitzil Melendez, Fidel, Ramirez Godinez, Francisco, Silva-Bravo, Fernando, Gane, Edward, Stedman, Catherine, Kwiatkowski, Mariusz, Wyrwicz, Lucjan, Nowakowska-Zajdel, Ewa, Kraj, Leszek, Janczewska, Ewa, Surma-Wlodarczyk, Renata, Breder, Valeriy, Sekacheva, Marina, Orlova, Rashida, Vasilyev, Alexander, Zukov, Ruslan, Vladimirov, Vladimir, Minguez, Beatriz, Matilla Pena, Ana, Fernandez Castroagudin, Javier, Romero Gomez, Manuel, Luis Lledo, Jose, Rubin, Angel, Garcia Sanchez, Araceli, Calleja Panero, Jose, Yu, Ming-Chin, Shen, Ying-Chun, Huang, Yi-Hsiang, Jeng, Long-Bin, Chang, Ting-Tsung, Yang, Sheng-Shun, Chen, Shinn-Cherng, Dechaphunkul, Arunee, Tanwandee, Tawesak, Leerapun, Apinya, Seker, Mesut, Harputluoglu, Hakan, Cicin, Irfan, Oksuzoglu, Berna, Bilici, Mehmet, Sezgin Goksu, Sema, Artac, Mehmet, Cil, Timucin, Yalcin, Suayib, Meyer, Tim, Sarker, Debashis, Rao, Ankit, Palmer, Daniel, Evans, Jeff, Hubner, Richard, Finn, Richard, Ulahannan, Susanna, Zakari, Ahmed, Feun, Lynn, Al-Rajabi, Raed, Sung, Max, He, Aiwu, Kardosh, Adel, Goyal, Lipika, Li, Daneng, Choi, Minsig, Posada, Juan, Dodlapati, Jyothi, Shroff, Rachna, Agrawal, Saurabh, Gopaluni, Srivalli, Akce, Mehmet, Alese, Olatunji, Baron, Ari, Dunne, Richard, Loaiza-Bonilla, Arturo, Frenette, Catherine, Llovet, Josep M, Kumada, Hiromitsu, Cheng, Ann-Lii, Galle, Peter R, Kaneko, Shuichi, Wang, Anran, Mody, Kalgi, Dutcus, Corina, Dubrovsky, Leonid, Siegel, Abby B, and Finn, Richard S

Published
2023
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4. Geriatric Assessment Scale for Optimal Management of Gastric Cancer in Older Adults Who Underwent Gastrectomy: A Systematic Review.

Author

Rodriguez-Arroyo, Brenda, Caraballo, Pedro, Pineda-Isaza, Alejandro, Arias-Valderrama, Oriana, Cleves, Manuel A., and Zambrano, Angela R.

Subjects
YOUNG adults, PROGNOSIS, OVERALL survival, STOMACH cancer, MEDICAL research
Abstract

Introduction: Stomach cancer is one of the most common causes of cancer worldwide, especially in the population over 65 years. The survival rate of the elderly is lower in comparison with young people, and they are underrepresented in clinical trials and research in general. The evaluation of Multidimensional Geriatric Assessment (MGA) would be key for assessing the prognosis of these patients and therefore having a more informed decision-making process when considering one of the most vulnerable populations. Methods: A search was performed in the OVID, Embase, and PubBMed databases. There was no restriction on publication time, language, or study design. Eligible studies were those that included geriatric patients with a diagnosis of nonmetastatic stomach cancer who receive oncospecific and surgical management, used Multidimensional/Comprehensive Geriatric Assessment (MGA), and which outcomes included at least overall survival, morbidity, and mortality. Results: Four studies were included, and the MGA battery was not implemented, but rather easily measurable scales such as nutritional status, functional status, cognitive and behavioral disorders, comorbidities, and polypharmacy. Some authors proposed that the assessment of overall survival is not explicit among the included studies; patients with gastric cancer and mild, moderate, severe, and total dependence had higher mortality than independent patients (39% [HR 1.39; 95% CI: 1.09–1.7], 68% [95% CI: 1.46–1.93], 187% [HR 2.87 95% CI: 2.47–3.34], and 234% [95% CI: 2.81–3.97]), respectively. The Zhou study showed an association between sarcopenia, assessed by imaging studies, and a longer hospital stay in days (16 [9] vs. 13 [6], p 0.004). The study by Pujara found that polypharmacy (OR 2.36 CI: 1.08–5.17) and weight loss greater than 10% in the past 6 months were associated with greater postoperative morbidity at 90 days (OR 2.36 CI: 1.08–5.17, OR 11.21 CI: 2.16–58.24). Conclusion: MGA was not broadly implemented. Geriatric assessment dependency appears to be a prognostic marker of survival in patients with gastric cancer. Sarcopenia appears to be an important prognostic marker for short- and long-term outcomes. Higher quality studies in this specific population are required to support the systematic use of this assessment for the choice of appropriate therapy according to the patient. [ABSTRACT FROM AUTHOR]

Published
2024
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5. Pembrolizumab plus concurrent chemoradiotherapy versus placebo plus concurrent chemoradiotherapy in patients with locally advanced squamous cell carcinoma of the head and neck (KEYNOTE-412): a randomised, double-blind, phase 3 trial

Author

Machiels, Jean-Pascal, primary, Tao, Yungan, additional, Licitra, Lisa, additional, Burtness, Barbara, additional, Tahara, Makoto, additional, Rischin, Danny, additional, Alves, Gustavo, additional, Lima, Iane Pinto Figueiredo, additional, Hughes, Brett G M, additional, Pointreau, Yoann, additional, Aksoy, Sercan, additional, Laban, Simon, additional, Greil, Richard, additional, Burian, Martin, additional, Hetnał, Marcin, additional, Delord, Jean-Pierre, additional, Mesía, Ricard, additional, Taberna, Miren, additional, Waldron, John N, additional, Simon, Christian, additional, Grégoire, Vincent, additional, Harrington, Kevin J, additional, Swaby, Ramona F, additional, Zhang, Yayan, additional, Gumuscu, Burak, additional, Bidadi, Behzad, additional, Siu, Lillian L, additional, Hughes, Brett GM, additional, Gao, Bo, additional, McGrath, Margaret, additional, Thurnher, Dietmar, additional, Fuereder, Thorsten, additional, Rottey, Sylvie, additional, Machiels, Jean-Pascal, additional, Clement, Paul M, additional, Henry, Stéphanie, additional, Deheneffe, Stéphanie, additional, Vasconcelos Alves, Gustavo, additional, Mourão Dias, Josiane, additional, De Marchi, Pedro Rafael Martins, additional, Mak, Milena Perez, additional, Pereira de Santana Gomes, Andrea Juliana, additional, Oliveira de Castro Junior, Dalvaro, additional, Motta, Tatiane Cardoso, additional, Agostinho Padoan, Monica Luciana, additional, Victorina, Ana Paula, additional, de Azevedo, Sergio Jobim, additional, Brule, Stephanie, additional, Hilton, John, additional, Wang, Chang Shu, additional, Bouganim, Nathaniel, additional, Webster, Marc, additional, Walker, John, additional, Chua, Neil, additional, Zambrano, Angela Regina, additional, Quiroga Echeverri, Alicia, additional, Niño Gomez, Oscar Mauricio, additional, Ortiz, Carlos Alberto, additional, Rojas, Luis, additional, Cardona Zorilla, Andrés, additional, Urrego Meléndez, Olga Marcela, additional, Holečková, Petra Beran, additional, Melichar, Bohuslav, additional, Cvek, Jakub, additional, Prausová, Jana, additional, Vošmik, Milan, additional, Zasadny, Xavier, additional, Geoffrois, Lionnel, additional, Fietkau, Rainer, additional, Haderlein, Marlen, additional, Mueller, Andreas H, additional, Schroeder, Ursula, additional, Wollenberg, Barbara, additional, Ivanyi, Philipp, additional, Gruenwald, Viktor, additional, Schafhausen, Philippe, additional, Gutfeld, Orit, additional, Gluck, Iris, additional, Popovtzer, Aron, additional, Meirovitz, Amichay, additional, Billan, Salem, additional, Brenner, Baruch, additional, Limon, Dror, additional, Perri, Francesco, additional, Caponigro, Francesco, additional, Violati, Martina, additional, Ferrari, Daris, additional, Nole, Franco, additional, Bertolini, Federica, additional, Livi, Lorenzo, additional, Ghi, Maria Grazia, additional, Imarisio, Ilaria, additional, Homma, Akihiro, additional, Ueda, Tsutomu, additional, Asada, Yukinori, additional, Yamazaki, Tomoko, additional, Matsumoto, Koji, additional, Fujii, Takashi, additional, Ikeda, Sadakatsu, additional, Takahashi, Shunji, additional, Kinoshita, Takashi, additional, Sasaki, Keita, additional, Tsuji, Akihito, additional, Ahn, Myung-Ju, additional, Cho, Byoung Chul, additional, Lee, Keun-Wook, additional, Lee, Ki Hyeong, additional, Choi, Moon Ki, additional, Yun, Hwan Jung, additional, Hendriks, Mathijs P, additional, Oosting, Sjoukje F, additional, Buter, Jan, additional, Van Meerten, Esther, additional, Graham, Jonathan, additional, Kawecki, Andrzej, additional, Debicka, Izabella, additional, Maciejczyk, Adam, additional, Pysz, Maciej, additional, Filarska, Dorota, additional, Koralewski, Piotr, additional, Wygoda, Andrzej, additional, Składowski, Krzysztof, additional, Talerczyk, Małgorzata, additional, Berrocal Jaime, Alfonso, additional, Pérez Segura, Pedro, additional, Braña García, Irene, additional, Basté Rotllan, Neus, additional, Mesía Nin, Ricard, additional, Taberna Sanz, Miren, additional, Iglesias Docampo, Lara, additional, Soria Rivas, Ainara, additional, Rueda Domínguez, Antonio, additional, Trigo Pérez, José Manuel, additional, Hong, Ruey-Long, additional, Li, Shau-Hsuan, additional, Wang, Hung-Ming, additional, Yen, Chia-Jui, additional, Yang, Muh-Hwa, additional, Chang, Yi-Fang, additional, Liu, Yi-Chun, additional, Lin, Jin-Ching, additional, Ekenel, Meltem, additional, Harputluoğlu, Hakan, additional, Özyilkan, Özgür, additional, Bılıcı, Ahmet, additional, Şendur, Mehmet Alı Nahıt, additional, Arslan, Cagatay, additional, Harrington, Kevin, additional, Ramkumar, Shanmugasundaram, additional, Gujral, Dorothy, additional, Stewart, Simon, additional, Powell, Melanie, additional, Sibtain, Amen, additional, Roques, Tom, additional, Yip, Kent, additional, Mirza, Arafat, additional, Sivaramalingam, Muthiah, additional, Belman, Neil D, additional, Agarwala, Sanjiv, additional, Anderson, Ian, additional, Patel, Arpan, additional, Maggiore, Ronald, additional, Baumgart, Megan, additional, Fidler, Mary Jo, additional, Kaur, Varinder, additional, Gaughan, Elizabeth, additional, Worden, Francis, additional, Rodriguez, Cristina P, additional, Sukari, Ammar, additional, Wong, Deborah, additional, Yom, Sue, additional, Walsh, William V, additional, Fiorillo, Joseph A, additional, Yorio, Jeffrey T, additional, and Obara, Grzegorz S, additional

Published
2024
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7. Lenvatinib plus pembrolizumab versus lenvatinib plus placebo for advanced hepatocellular carcinoma (LEAP-002): a randomised, double-blind, phase 3 trial

Author

Llovet, Josep M, primary, Kudo, Masatoshi, additional, Merle, Philippe, additional, Meyer, Tim, additional, Qin, Shukui, additional, Ikeda, Masafumi, additional, Xu, Ruocai, additional, Edeline, Julien, additional, Ryoo, Baek-Yeol, additional, Ren, Zhenggang, additional, Masi, Gianluca, additional, Kwiatkowski, Mariusz, additional, Lim, Ho Yeong, additional, Kim, Jee Hyun, additional, Breder, Valeriy, additional, Kumada, Hiromitsu, additional, Cheng, Ann-Lii, additional, Galle, Peter R, additional, Kaneko, Shuichi, additional, Wang, Anran, additional, Mody, Kalgi, additional, Dutcus, Corina, additional, Dubrovsky, Leonid, additional, Siegel, Abby B, additional, Finn, Richard S, additional, Strasser, Simone, additional, Thompson, Alexander, additional, Roohullah, Aflah, additional, Sievert, William, additional, Andelkovic, Vladimir, additional, Knox, Jennifer, additional, Davies, Janine, additional, Asselah, Jamil, additional, Brahmania, Mayur, additional, Majeed, Habeeb, additional, Villanueva, Luis, additional, Yanez Weber, Patricio, additional, Garrido, Marcelo, additional, Pizarro, Gonzalo Ignacio, additional, Yanez, Nicolas, additional, Ou, Shuangyan, additional, Pan, Hongming, additional, Meng, Zhiqiang, additional, Gu, Kangsheng, additional, Chen, Xi, additional, Zhang, Tao, additional, Hao, Chunyi, additional, Cao, Peiguo, additional, Guo, Yabing, additional, Xiao, Juxiang, additional, Fang, Weijia, additional, Wang, Xin, additional, Bai, Yuxian, additional, Chen, Xiaoming, additional, Yan, Dong, additional, Zhao, Hong, additional, Ying, Jieer, additional, Bonilla, Carlos, additional, Urrego, Olga, additional, Zambrano, Angela, additional, Lema, Mauricio, additional, Restrepo Gutierrez, Juan Carlos, additional, Cardona, Andres, additional, Franco Millan, Sandra, additional, Oscar, Madiedo, additional, Ramos, Victor, additional, LeSourd, Samuel, additional, Bronowicki, Jean-Pierre, additional, Bourliere, Marc, additional, Cattan, Stephane, additional, Bouattour, Mohamed, additional, Mineur, Laurent, additional, Regnault, Helene, additional, Dauvois, Barbara, additional, Schulze, Kornelius, additional, Folprecht, Gunnar, additional, Geier, Andreas, additional, Waidmann, Oliver, additional, Finkelmeier, Fabian, additional, Venerito, Marino, additional, Berres, Marie-Luise, additional, Berg, Thomas, additional, Lange, Christian, additional, Schmidt, Hartmut, additional, Waldschmidt, Dirk T, additional, Bitzer, Michael, additional, McDermott, Ray, additional, Duffy, Austin, additional, Zagonel, Vittorina, additional, Tonini, Giuseppe, additional, Piscaglia, Fabio, additional, Gori, Stefania, additional, Rizzo, Mimma, additional, Biscaldi, Elisa, additional, Foltran, Luisa, additional, Cabibbo, Giuseppe, additional, Aikata, Hiroshi, additional, Numata, Kazushi, additional, Marusawa, Hiroyuki, additional, Kato, Naoya, additional, Kurosaki, Masayuki, additional, Morimoto, Manabu, additional, Yamashita, Tatsuya, additional, Koga, Hironori, additional, Masaki, Tsutomu, additional, Tateishi, Ryosuke, additional, Inaba, Yoshitaka, additional, Arakawa, Tomohiro, additional, Suzuki, Yoshiyuki, additional, Akua, Norio, additional, Kobayashi, Masahiro, additional, Hosaka, Tetsuya, additional, Nakamuta, Makoto, additional, Oza, Noriko, additional, Kondo, Shunsuke, additional, Furuse, Junji, additional, Nagashima, Fumio, additional, Kitano, Masayuki, additional, Takaguchi, Koichi, additional, Kim, Tae-You, additional, Kim, Han Sang, additional, Hernandez Hernandez, Carlos, additional, Motola Kuba, Daniel, additional, Segura Gonzalez, Manuel, additional, Cabrera Luviano, Jesus, additional, Huitzil Melendez, Fidel, additional, Ramirez Godinez, Francisco, additional, Silva-Bravo, Fernando, additional, Gane, Edward, additional, Stedman, Catherine, additional, Wyrwicz, Lucjan, additional, Nowakowska-Zajdel, Ewa, additional, Kraj, Leszek, additional, Janczewska, Ewa, additional, Surma-Wlodarczyk, Renata, additional, Sekacheva, Marina, additional, Orlova, Rashida, additional, Vasilyev, Alexander, additional, Zukov, Ruslan, additional, Vladimirov, Vladimir, additional, Minguez, Beatriz, additional, Matilla Pena, Ana, additional, Fernandez Castroagudin, Javier, additional, Romero Gomez, Manuel, additional, Luis Lledo, Jose, additional, Rubin, Angel, additional, Garcia Sanchez, Araceli, additional, Calleja Panero, Jose, additional, Yu, Ming-Chin, additional, Shen, Ying-Chun, additional, Huang, Yi-Hsiang, additional, Jeng, Long-Bin, additional, Chang, Ting-Tsung, additional, Yang, Sheng-Shun, additional, Chen, Shinn-Cherng, additional, Dechaphunkul, Arunee, additional, Tanwandee, Tawesak, additional, Leerapun, Apinya, additional, Seker, Mesut, additional, Harputluoglu, Hakan, additional, Cicin, Irfan, additional, Oksuzoglu, Berna, additional, Bilici, Mehmet, additional, Sezgin Goksu, Sema, additional, Artac, Mehmet, additional, Cil, Timucin, additional, Yalcin, Suayib, additional, Sarker, Debashis, additional, Rao, Ankit, additional, Palmer, Daniel, additional, Evans, Jeff, additional, Hubner, Richard, additional, Finn, Richard, additional, Ulahannan, Susanna, additional, Zakari, Ahmed, additional, Feun, Lynn, additional, Al-Rajabi, Raed, additional, Sung, Max, additional, He, Aiwu, additional, Kardosh, Adel, additional, Goyal, Lipika, additional, Li, Daneng, additional, Choi, Minsig, additional, Posada, Juan, additional, Dodlapati, Jyothi, additional, Shroff, Rachna, additional, Agrawal, Saurabh, additional, Gopaluni, Srivalli, additional, Akce, Mehmet, additional, Alese, Olatunji, additional, Baron, Ari, additional, Dunne, Richard, additional, Loaiza-Bonilla, Arturo, additional, and Frenette, Catherine, additional

Published
2023
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8. Opening Statements

Author

Gordon, Erin, Winny, Annalies, Davis, Jenny B., and Zambrano, Angela C.

Published
2018

13. The Unique Spectrum of MUTYH Germline Mutations in Colombian Patients with Extracolonic Carcinomas

Author

Rodriguez-Rojas,Lisa Ximena, Candelo,Estephania, Pachajoa,Harry, Garcia-Robledo,Juan Esteban, Nastasi-Catanese,Jose Antonio, Olave-Rodriguez,Jorge Andres, Zambrano,Angela R, Rodriguez-Rojas,Lisa Ximena, Candelo,Estephania, Pachajoa,Harry, Garcia-Robledo,Juan Esteban, Nastasi-Catanese,Jose Antonio, Olave-Rodriguez,Jorge Andres, and Zambrano,Angela R

Abstract

Lisa Ximena Rodriguez-Rojas,1,2 Estephania Candelo,3,4 Harry Pachajoa,1,2,4 Juan Esteban Garcia-Robledo,3 Jose Antonio Nastasi-Catanese,1,2 Jorge Andres Olave-Rodriguez,2 Angela R Zambrano5 1Department of Human Genetics, Fundación Valle del Lili, Cali, Colombia; 2Faculty of Health Sciences, Universidad Icesi, Cali, Colombia; 3Fundación Valle del Lili, Centro de Investigaciones Clínicas, Cali, Colombia; 4Centro de Investigaciones en Anomalías Congénitas y Enfermedades Raras, Universidad Icesi, Cali, Colombia; 5Department of Hematology/Oncology, Fundación Valle del Lili, Cali, ColombiaCorrespondence: Lisa Ximena Rodriguez-Rojas, Department of Human Genetics, Fundación Valle del Lili, Cali, 760032, Colombia, Email lisa.rodriguez@fvl.org.coBackground: Protein MUTYH, encoded by the gene MUTYH, is an important mismatch repair enzyme in the base-excision repair pathway of DNA repair. When genetically altered, different neoplastic conditions can arise. One of the widely known syndromes associated with MUTYH mutations is MUTYH-associated polyposis, a form of familial colorectal cancer syndrome. MUTYH may also be a driver in other familial cancer syndromes, as well as breast cancer and spontaneous cancer cases. However, some controversies about the role of these alterations in oncogenesis remain, especially when affected in a heterozygous way. Most available data on MUTYH mutations are on Caucasian patients.Material and Methods: We analyzed a small cohort of non-Caucasian, Colombian cancer patients with MUTYH germline heterozygous mutations, clinical features suggestive of familial cancer, and extensive genetic studies with no other mutations and without MUTYH-associated polyposis.Conclusion: With this case series, we intended to provide important data for the understanding of MUTYH as a possible driver of familial cancer, even when only heterozygous mutations are found.Keywords: MUTYH mutations, familial cancer, heterozygote MUTYH mutation, Colombia

Published
2023

15. Innovative Methodology for Strengthening a Multidisciplinary Team Approach in Cities in Low- and Middle-Income Countries

Author

Eaton, Vanessa, primary, Zambrano, Angela, additional, Sanabria, Valeria, additional, Lopez, Roberto, additional, Kyei, Ishmael, additional, Mra, Rai, additional, Sarchet, Vanessa, additional, Kremzier, Megan, additional, Borras, Josep, additional, Aung, Thet Ko, additional, Morton Doherty, Rebecca, additional, Henshall, Susan, additional, and Camacho, Rolando, additional

Published
2022
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17. Civil evidence.

Author

Zambrano, Angela C.

Subjects
Civil procedure -- Surveys, Evidence (Law) -- Surveys
Published
2010

18. Civil evidence.

Author

Zambrano, Angela C. and D'Amico, Brian

Subjects
Civil procedure -- Surveys, Evidence (Law) -- Surveys
Published
2009

19. Civil evidence.

Author

Zambrano, Angela C., Allen, Margaret H., and O'Connor, John

Subjects
Civil procedure -- Surveys, Evidence (Law) -- Surveys
Published
2008

20. Civil evidence.

Author

Zambrano, Angela C., Allen, Margaret H., and Blanchard, Aimee N.

Subjects
Civil procedure -- Surveys, Evidence (Law) -- Surveys
Published
2007

21. VIOLENCIAS Y PAZ EN COLOMBIA: CONSIDERACIONES A PARTIR DE LA POLÍTICA PÚBLICA CÁTEDRA DE LA PAZ

Author

Franco, Sara Velásquez, Zambrano, Angela Camila Ayala, Carvalho, Maria Inez da Silva de Souza, de Sá, Maria Roseli Gomes Brito, Franco, Sara Velásquez, Zambrano, Angela Camila Ayala, Carvalho, Maria Inez da Silva de Souza, and de Sá, Maria Roseli Gomes Brito

Abstract

Las consideraciones de este artículo se construyen a partir de uno de los desafíos que enfrenta la sociedad colombiana: el trabajo que trae consigo el pos-acuerdo que resulta en Colombia después de la firma de la paz entre el Gobierno y las FARC–EP bajo la perspectiva que ofrece el estudio del Ciclo de Políticas de Stephen Ball. Para ello, la educación es considerada Institución clave para este proceso, vista como espacio de reconstrucción social, de diálogo y reconocimiento del otro (AYALA; SÁ, 2019) recibe en específico la política pública Ley 1732, llamada Cátedra de la paz, que desde nuestra lectura busca propiciar la reflexión, el conocimiento de la história colombiana, favorecer las prácticas de reconciliación y el perdón a partir del dialogo de saberes. Entender la política como texto - writerly -, discurso - readly - o explorar otras posibilidades a partir de los estudios del campo curricular, permitirá hacerle frente a las violencias en Colombia, que por años representa aceptar que la zozobra y el miedo se han instalado en pequeños y grandes contextos tanto urbanos y rurales.

Published
2020

22. Practicing Gratitude.

Author

Zambrano, Angela C.

Subjects
Gratitude -- Influence -- Management, Working mothers -- Management -- Psychological aspects, Company business management
Abstract

Making It Work is a column in partnership with the Working Mother Best Law Firms for Women initiative in which lawyers share how they manage both life's challenges and work's [...]

Published
2018

25. Attorneys' fees.

Author

Miller, Ralph I., Zambrano, Angela C., and Pitcher, David E.

Subjects
Attorneys -- Fees, Attorneys -- Surveys
Published
2005

26. Attorneys' fees.

Author

Miller, Ralph I., Zambrano, Angela C., and Hartmann, Michelle

Subjects
Attorneys -- Fees, Attorneys -- Surveys
Published
2004

28. Reconociendo el valor de la hospitalización de la Diada como parte del cáncer en la vida misma

Author

Combita Zambrano, Angela Maria, Universidad Nacional de Colombia, and Chaparro Díaz, Lorena

Subjects
Hospitalization, Caregivers, Chronic Illness, Neoplasms, Enfermedad crónica, Hospitalización, Atención al Paciente, Cuidadores, Patient Care, Neoplasias (Decs y MesH)
Abstract

El cáncer es una enfermedad que para la persona implica en varias de sus etapas una condición de dependencia y se necesita de alguien que acompañe la trayectoria del paciente, es ahí donde surge el cuidador familiar. Este vínculo tiene particularidades durante la etapa de la hospitalización que puede afectar su biografía y percepción de sobrecarga. Objetivo: Describir el vínculo de la diada (persona con cáncer – Cuidador familiar) durante el momento de hospitalización en un Hospital Universitario en Bogotá Metodología: Es un estudio cualitativo, descriptivo con enfoque de Teoría fundamentada en el que participaron 14 diadas. Se utilizó entrevista semiestructurada y observación participante. Se analizaron mediante abordaje de codificación abierta, axial y selectiva para cada miembro de la diada por separado y uno final de los datos como diada. En todo el proceso se tuvo en cuenta la comparación constante. Resultados: Se derivaron 20 subcategorías, de las cuales 7 eran de la persona con cáncer, 6 del cuidador familiar y 7 de la Diada. Al final se identifican 7 patrones en común que permitieron surgir la categoría central: Reconociendo el valor de la hospitalización de la diada como parte del cáncer en la vida misma. Conclusión: El planteamiento teórico propone que cada integrante de la diada (PEC-CF) contribuye y percibe de manera complementaria el vínculo establecido en el periodo de hospitalización, tienen acciones de empatía de manera concreta o implícita, la relación es dinámica y percibía como positiva y negativa según el contexto, hay expresiones de reciprocidad en la toma de decisiones y valoran esta etapa del proceso de cronicidad como una oportunidad y momento de oro para darle sentido a la vida Abstract: Cancer is adisease that for the person implies in several of its stages a condition of dependency and it needs someone to accompany the path of the patient that is where the family caregiver emerges. This link has particularities during the stage of hospitalization that may affect his biography and perception of overload. Objective:To describe the link of the dyad (person with cancer -Family Caregiver) during the time of hospitalization in a University Hospital in Bogotá. Methodology: This is a qualitative, descriptive study with an approach of grounded theory in which 14 dyads participated. Semi-structured interview and participant observation were used. They were analyzed using an open, axial and selective coding approach for each member of the dyad separately anda final one of the data as a dyad. The constant comparison was taken into account throughout the process. Results:20 subcategories were derived, of which 7 were from the person with cancer, 6 from the family caregiver and 7 from the Dyad. In the end, 7 common patterns were identified that allowed the emergence of the central category: Recognizing the value of the hospitalization of the dyad as part of cancer in life itself. Conclusion: The theoretical approach proposes that each member of the dyad (PEC-CF) contributes and perceives in a complementary way the link established in the hospitalization period, they have empathy actions in a concrete or implicit way, the relationship is dynamic and perceived as positive and negative according to the context, there are expressions of reciprocity in decision-making and they value this stage of the chronicity process as a golden opportunity and moment to make sense of life. Maestría

Published
2019

29. Narrativas de estudantes sobre o conflito armado colombiano: uma conversa com currículo escolar

Author

Ayala Zambrano, Angela Camila, Sá, Maria Roseli Gomes Brito de, Sales, Márcea Andrade, Zen, Giovanna Cristina, and Almeida, Vanessa Sievers de

Subjects
Conflito Armado Colombiano, Educação para paz, Curriculum currere, Currículos, Educação, Armed Conflict Colombiano, Construção da paz, Currículo, Curriculo Currere, Guerrilhas- Colômbia - Narrativas pessoais, Narratives, Educação Colômbia- Aspectos sociais, Narrativas
Abstract

Submitted by Angela Camila Ayala Zambrano (cami9013@gmail.com) on 2019-07-13T19:11:28Z No. of bitstreams: 1 Narrativas de estudantes sobre o conflito armado colombiano um conversa com o curriculo escolar.pdf: 4443674 bytes, checksum: b1a567374afd34d7fc34488698a4fb23 (MD5) Approved for entry into archive by Ana Miria Moreira (anamiriamoreira@hotmail.com) on 2019-08-12T13:32:13Z (GMT) No. of bitstreams: 1 Narrativas de estudantes sobre o conflito armado colombiano um conversa com o curriculo escolar.pdf: 4443674 bytes, checksum: b1a567374afd34d7fc34488698a4fb23 (MD5) Made available in DSpace on 2019-08-12T13:32:13Z (GMT). No. of bitstreams: 1 Narrativas de estudantes sobre o conflito armado colombiano um conversa com o curriculo escolar.pdf: 4443674 bytes, checksum: b1a567374afd34d7fc34488698a4fb23 (MD5) Conselho Nacional de Pesquisa CNPq O presente trabalho apresenta o relato de pesquisa de mestrado que teve como objetivo compreender as concepções sobre conflito armado na Colômbia de estudantes do décimo ano de uma escola pública em Bogotá através de suas narrativas, para a discussão desta temática no currículo escolar. Ante a violência prolongada durante mais de seis décadas e sua progressiva degradação, causando impactos de diversas ordens para o conjunto da sociedade colombiana, o estudo questiona o lugar da Cátedra da Paz instituída pelo Estado, no currículo das escolas. O referencial teórico situa historicamente o conflito armado colombiano, aborda a concepção de currículo como currere de W. Pinar, o estudante como ator do currículo e a importância da memória social e das narrativas. A narrativa neste estudo está delineada em três dimensões, a primeira configura a narrativa como dispositivo formativo, narrativas levando os estudantes a reconhecerem-se como sujeitos em formação; como aspecto metodológico na prática educativa e também caracteriza a terceira dimensão conferida à narrativa, desta vez referindo-se ao próprio caminho metodológico adotado para realização desta pesquisa, que assume seu enfoque hermenêutico. A proposta investigativa se mostrou também como um compromisso pedagógico o qual buscou gerar uma reflexão na comunidade educativa sobre os desafios que se devem assumir para a consolidação de espaços de paz a partir da educação e mais especificamente do currículo escolar. O entrecruzamento de histórias produz uma sobreposição de saberes para cultivar a história local; um exercício indispensável da atenção e do interesse social. Daí a importância e a necessidade de espaços que facilitem a relação, a memória coletiva e a educação para a memória como valorização individual e coletiva. ABSTRACT The present work presents the report of master 's research that had as objective to understand the conceptions about armed conflict in Colombia of students of the tenth year of a public school in Bogotá through their narratives, for the discussion of this theme in the school curriculum. Faced with the prolonged violence for more than six decades and its progressive degradation, causing impacts of diverse orders for the whole of Colombian society, the study questions the place of the Chair of Peace instituted by the State, in the curriculum of the schools. The theoretical framework historically situates the Colombian armed conflict, approaches the curriculum conception as currere of W. Pinar, the student as an actor of the curriculum and the importance of social memory and narratives. The narrative in this study is outlined in three dimensions, the first one configures narrative as a formative device, narratives leading students to recognize themselves as subjects in formation; as a methodological aspect in educational practice and also characterizes the third dimension given to the narrative, this time referring to the methodological path adopted to carry out this research, which assumes its hermeneutic approach. The research proposal also showed itself as a pedagogical commitment which sought to generate a reflection in the educational community on the challenges that must be assumed for the consolidation of spaces of peace from education and more specifically the school curriculum. The intertwining of stories produces an overlap of knowledge to cultivate local history; an indispensable exercise of attention and social interest. Hence the importance and the need of spaces that facilitate the relation, the collective memory and the education for the memory like individual and collective valorization

Published
2019

30. Wavering over consumer class actions

Author

Zambrano, Angela C., Velevis, Robert S., and Barnett, Kent

Subjects
Class actions (Civil procedure), Contract agreement, Banking, finance and accounting industries
Abstract

Contractual class action waivers in consumer arbitration clauses have become commonplace in consumer agreements, particularly in the consumer financial services industry. As more companies have included these provisions in their [...]

Published
2008

31. Fighting on all fronts: successfully managing multi-jurisdictional employment litigation.

Author

Zambrano, Angela C. and Montgomery, Paige Holden

Subjects
Multijurisdictional practice (Law) -- Laws, regulations and rules, Res judicata -- Laws, regulations and rules, Government regulation
Abstract

The authors discuss several practical and procedural techniques that can be used to maximize an employer's chances of success in multi-jurisdictional employment litigation. ********** Imagine the following scenario. The assistant [...]

Published
2007

32. Pembrolizumab alone or with chemotherapy versus cetuximab with chemotherapy for recurrent or metastatic squamous cell carcinoma of the head and neck (KEYNOTE-048): a randomised, open-label, phase 3 study

Author

Burtness, Barbara, primary, Harrington, Kevin J, additional, Greil, Richard, additional, Soulières, Denis, additional, Tahara, Makoto, additional, de Castro, Gilberto, additional, Psyrri, Amanda, additional, Basté, Neus, additional, Neupane, Prakash, additional, Bratland, Åse, additional, Fuereder, Thorsten, additional, Hughes, Brett G M, additional, Mesía, Ricard, additional, Ngamphaiboon, Nuttapong, additional, Rordorf, Tamara, additional, Wan Ishak, Wan Zamaniah, additional, Hong, Ruey-Long, additional, González Mendoza, René, additional, Roy, Ananya, additional, Zhang, Yayan, additional, Gumuscu, Burak, additional, Cheng, Jonathan D, additional, Jin, Fan, additional, Rischin, Danny, additional, Lerzo, Guillermo, additional, Tatangelo, Marcelo, additional, Varela, Mirta, additional, Zarba, Juan Jose, additional, Boyer, Michael, additional, Gan, Hui, additional, Gao, Bo, additional, Hughes, Brett, additional, Mallesara, Girish, additional, Taylor, Anne, additional, Burian, Martin, additional, Barrios, Carlos Henrique, additional, de Castro Junior, Dalvaro Oliveira, additional, Castro, Gilberto, additional, Franke, Fabio Andre, additional, Girotto, Gustavo, additional, Lima, Iane Pinto Figueiredo, additional, Nicolau, Ulisses Ribaldo, additional, Pinto, Gustavo Dix Junqueira, additional, Santos, Lucas, additional, Victorino, Ana-Paula, additional, Chua, Neil, additional, Couture, Felix, additional, Gregg, Richard, additional, Hansen, Aaron, additional, Hilton, John, additional, McCarthy, Joy, additional, Soulieres, Denis, additional, Ascui, Rodrigo, additional, Gonzalez, Pablo, additional, Villanueva, Luis, additional, Torregroza, Marco, additional, Zambrano, Angela, additional, Holeckova, Petra, additional, Kral, Zdenek, additional, Melichar, Bohuslav, additional, Prausova, Jana, additional, Vosmik, Milan, additional, Andersen, Maria, additional, Gyldenkerne, Niels, additional, Jurgens, Hannes, additional, Putnik, Kadri, additional, Reinikainen, Petri, additional, Gruenwald, Viktor, additional, Laban, Simon, additional, Aravantinos, Gerasimos, additional, Boukovinas, Ioannis, additional, Georgoulias, Vassilis, additional, Kwong, Dora, additional, Al-Farhat, Yousuf, additional, Csoszi, Tibor, additional, Erfan, Jozsef, additional, Horvai, Geza, additional, Landherr, Laszlo, additional, Remenar, Eva, additional, Ruzsa, Agnes, additional, Szota, Judit, additional, Billan, Salem, additional, Gluck, Iris, additional, Gutfeld, Orit, additional, Popovtzer, Aron, additional, Benasso, Marco, additional, Bui, Simona, additional, Ferrari, Vittorio, additional, Licitra, Lisa, additional, Nole, Franco, additional, Fujii, Takashi, additional, Fujimoto, Yasushi, additional, Hanai, Nobuhiro, additional, Hara, Hiroki, additional, Matsumoto, Koji, additional, Mitsugi, Kenji, additional, Monden, Nobuya, additional, Nakayama, Masahiro, additional, Okami, Kenji, additional, Oridate, Nobuhiko, additional, Shiga, Kiyoto, additional, Shimizu, Yasushi, additional, Sugasawa, Masashi, additional, Takahashi, Masanobu, additional, Takahashi, Shunji, additional, Tanaka, Kaoru, additional, Ueda, Tsutomu, additional, Yamaguchi, Hironori, additional, Yamazaki, Tomoko, additional, Yasumatsu, Ryuji, additional, Yokota, Tomoya, additional, Yoshizaki, Tomokazu, additional, Kudaba, Iveta, additional, Stara, Zinaida, additional, Cheah, Soon Keat, additional, Aguilar Ponce, Jose, additional, Gonzalez Mendoza, Rene, additional, Hernandez Hernandez, Carlos, additional, Medina Soto, Francisco, additional, Buter, Jan, additional, Hoeben, Ann, additional, Oosting, S., additional, Suijkerbuijk, Karijn, additional, Bratland, Aase, additional, Brydoey, Marianne, additional, Alvarez, Renzo, additional, Mas, Luis, additional, Caguioa, Priscilla, additional, Querol, John, additional, Regala, Eugenio Emmanuel, additional, Tamayo, Maria Belen, additional, Villegas, Ellie May, additional, Kawecki, Andrzej, additional, Karpenko, Andrey, additional, Klochikhin, Arkadiy, additional, Smolin, Alexey, additional, Zarubenkov, Oleg, additional, Goh, Boon Cher, additional, Cohen, Graham, additional, du Toit, Johanna, additional, Jordaan, Christa, additional, Landers, Gregory, additional, Ruff, Paul, additional, Szpak, Waldemar, additional, Tabane, Neonyana, additional, Brana, Irene, additional, Iglesias Docampo, Lara, additional, Lavernia, Javier, additional, Mesia, Ricard, additional, Abel, Edvard, additional, Muratidu, Valentina, additional, Nielsen, Niels, additional, Cristina, Valerie, additional, Rothschild, Sacha, additional, Wang, Hung-Ming, additional, Yang, Muh-Hwa, additional, Yeh, Su-Peng, additional, Yen, Chia-Jui, additional, Soparattanapaisarn, Nopadol, additional, Sriuranpong, Virote, additional, Aksoy, Sercan, additional, Cicin, Irfan, additional, Ekenel, Meltem, additional, Harputluoglu, Hakan, additional, Ozyilkan, Ozgur, additional, Harrington, Kevin, additional, Agarwala, Sanjiv, additional, Ali, Haythem, additional, Alter, Robert, additional, Anderson, Daniel, additional, Bruce, Justine, additional, Burtness, Barbara, additional, Campbell, Nicholas, additional, Conde, Miguel, additional, Deeken, John, additional, Edenfield, William, additional, Feldman, Lawrence, additional, Gaughan, Elizabeth, additional, Goueli, Basem, additional, Halmos, Balazs, additional, Hegde, Upendra, additional, Hunis, Brian, additional, Jotte, Robert, additional, Karnad, Anand, additional, Khan, Saad, additional, Laudi, Noel, additional, Laux, Douglas, additional, Martincic, Danko, additional, McCune, Steven, additional, McGaughey, Dean, additional, Misiukiewicz, Krzysztof, additional, Mulford, Deborah, additional, Nadler, Eric, additional, Nunnink, Johannes, additional, Ohr, James, additional, O'Malley, Meaghan, additional, Patson, Brian, additional, Paul, Doru, additional, Popa, Elizabeta, additional, Powell, Steven, additional, Redman, Rebecca, additional, Rella, Vincent, additional, Rocha Lima, Chaio, additional, Sivapiragasam, Abirami, additional, Su, Yungpo, additional, Sukari, Ammar, additional, Wong, Stuart, additional, Yilmaz, Emrullah, additional, and Yorio, Jeffrey, additional

Published
2019
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34. Pembrolizumab versus chemotherapy for previously untreated, PD-L1-expressing, locally advanced or metastatic non-small-cell lung cancer (KEYNOTE-042): a randomised, open-label, controlled, phase 3 trial

Author

Mok, Tony S K, primary, Wu, Yi-Long, additional, Kudaba, Iveta, additional, Kowalski, Dariusz M, additional, Cho, Byoung Chul, additional, Turna, Hande Z, additional, Castro, Gilberto, additional, Srimuninnimit, Vichien, additional, Laktionov, Konstantin K, additional, Bondarenko, Igor, additional, Kubota, Kaoru, additional, Lubiniecki, Gregory M, additional, Zhang, Jin, additional, Kush, Debra, additional, Lopes, Gilberto, additional, Adamchuk, Grigory, additional, Ahn, Myung-Ju, additional, Alexandru, Aurelia, additional, Altundag, Ozden, additional, Alyasova, Anna, additional, Andrusenko, Orest, additional, Aoe, Keisuke, additional, Araujo, Antonio, additional, Aren, Osvaldo, additional, Arrieta Rodriguez, Oscar, additional, Ativitavas, Touch, additional, Avendano, Oscar, additional, Barata, Fernando, additional, Barrios, Carlos Henrique, additional, Beato, Carlos, additional, Bergstrom, Per, additional, Betticher, Daniel, additional, Bolotina, Larisa, additional, Botha, Michiel, additional, Buddu, Sayeuri, additional, Caglevic, Christian, additional, Cardona, Andres, additional, Castro, Hugo, additional, Cay Senler, Filiz, additional, Cerny, Carlos Alexandre Sydow, additional, Cesas, Alvydas, additional, Chan, Gee-Chen, additional, Chang, Jianhua, additional, Chen, Gongyan, additional, Chen, Xi, additional, Cheng, Susanna, additional, Cheng, Ying, additional, Cherciu, Nelly, additional, Chiu, Chao-Hua, additional, Cicenas, Saulius, additional, Ciurescu, Daniel, additional, Cohen, Graham, additional, Costa, Marcos Andre, additional, Danchaivijitr, Pongwut, additional, De Angelis, Flavia, additional, de Azevedo, Sergio Jobim, additional, Dediu, Mircea, additional, Deliverski, Tsvetan, additional, De Marchi, Pedro Rafael Martins, additional, de The Bustamante Valles, Flor, additional, Ding, Zhenyu, additional, Doganov, Boyan, additional, Dreosti, Lydia, additional, Duarte, Ricardo, additional, Edusma-Dy, Regina, additional, Emelyanov, Sergey, additional, Erman, Mustafa, additional, Fan, Yun, additional, Fein, Luis, additional, Feng, Jifeng, additional, Fenton, David, additional, Fernandes, Gustavo, additional, Ferreira, Carlos, additional, Franke, Fabio Andre, additional, Freitas, Helano, additional, Fujisaka, Yasuhito, additional, Galindo, Hector, additional, Galvez, Christina, additional, Ganea, Doina, additional, Gil, Nuno, additional, Girotto, Gustavo, additional, Goker, Erdem, additional, Goksel, Tuncay, additional, Gomez Aubin, Gonzalo, additional, Gomez Wolff, Luis, additional, Griph, Hakan, additional, Gumus, Mahmut, additional, Hall, Jacqueline, additional, Hart, Gregory, additional, Havel, Libor, additional, He, Jianxing, additional, He, Yong, additional, Hernandez Hernandez, Carlos, additional, Hespanhol, Venceslau, additional, Hirashima, Tomonori, additional, Ho, Chung Man James, additional, Horiike, Atsushi, additional, Hosomi, Yukio, additional, Hotta, Katsuyuki, additional, Hou, Mei, additional, How, Soon Hin, additional, Hsia, Te-Chun, additional, Hu, Yi, additional, Ichiki, Masao, additional, Imamura, Fumio, additional, Ivashchuk, Oleksandr, additional, Iwamoto, Yasuo, additional, Jaal, Jana, additional, Jassem, Jacek, additional, Jordaan, Christa, additional, Juergens, Rosalyn Anne, additional, Kaen, Diego, additional, Kalinka-Warzocha, Ewa, additional, Karaseva, Nina, additional, Karaszewska, Boguslawa, additional, Kazarnowicz, Andrzej, additional, Kasahara, Kazuo, additional, Katakami, Nobuyuki, additional, Kato, Terufumi, additional, Kawaguchi, Tomoya, additional, Kim, Joo Hang, additional, Kishi, Kazuma, additional, Kolek, Vitezslav, additional, Koleva, Marchela, additional, Kolman, Petr, additional, Koubkova, Leona, additional, Kowalyszyn, Ruben, additional, Kowalski, Dariusz, additional, Koynov, Krassimir, additional, Ksienski, Doran, additional, Kurata, Takayasu, additional, Kuusk, Gerli, additional, Kuzina, Lyudmila, additional, Laczo, Ibolya, additional, Ladrera, Guia Elena Imelda, additional, Laktionov, Konstantin, additional, Landers, Gregory, additional, Lazarev, Sergey, additional, Lerzo, Guillermo, additional, Lesniewski Kmak, Krzysztof, additional, Li, Wei, additional, Liam, Chong Kin, additional, Lifirenko, Igor, additional, Lipatov, Oleg, additional, Liu, Xiaoqing, additional, Liu, Zhe, additional, Lo, Sing Hung, additional, Lopes, Valeria, additional, Lopez, Karla, additional, Lu, Shun, additional, Martinengo, Gaston, additional, Mas, Luis, additional, Matrosova, Marina, additional, Micheva, Rumyana, additional, Milanova, Zhasmina, additional, Miron, Lucian, additional, Mok, Tony, additional, Molina, Matias, additional, Murakami, Shuji, additional, Nakahara, Yasuharu, additional, Nguyen, Tien Quang, additional, Nishimura, Takashi, additional, Ochsenbein, Adrian, additional, Ohira, Tatsuo, additional, Ohman, Ronny, additional, Ong, Choo Khoon, additional, Ostoros, Gyula, additional, Ouyang, Xuenong, additional, Ovchinnikova, Elena, additional, Ozyilkan, Ozgur, additional, Petruzelka, Lubos, additional, Pham, Xuan Dung, additional, Picon, Pablo, additional, Piko, Bela, additional, Poltoratsky, Artem, additional, Ponomarova, Olga, additional, Popelkova, Patrice, additional, Purkalne, Gunta, additional, Qin, Shukui, additional, Ramlau, Rodryg, additional, Rappaport, Bernardo, additional, Rey, Felipe, additional, Richardet, Eduardo, additional, Roubec, Jaromir, additional, Ruff, Paul, additional, Rusyn, Andrii, additional, Saka, Hideo, additional, Salas, Jorge, additional, Sandoval, Mario, additional, Santos, Lucas, additional, Sawa, Toshiyuki, additional, Seetalarom, Kasan, additional, Seker, Mesut, additional, Seki, Nobuhiko, additional, Seolwane, Freddy, additional, Shepherd, Lucinda, additional, Shevnya, Sergii, additional, Shimada, Andrea Kazumi, additional, Shparyk, Yaroslav, additional, Sinielnikov, Ivan, additional, Sirbu, Daniela, additional, Smaletz, Oren, additional, Soares, Joao Paulo Holanda, additional, Sookprasert, Aumkhae, additional, Speranza, Giovanna, additional, Sriuranpong, Virote, additional, Stara, Zinaida, additional, Su, Wu-Chou, additional, Sugawara, Shunichi, additional, Szpak, Waldemar, additional, Takahashi, Kazuhisa, additional, Takigawa, Nagio, additional, Tanaka, Hiroshi, additional, Tan Chun Bing, Jerry, additional, Tang, Qiyou, additional, Taranov, Pavel, additional, Tejada, Hermes, additional, Tho, Lye Mun, additional, Torii, Yoshitaro, additional, Trukhyn, Dmytro, additional, Turdean, Maria, additional, Turna, Hande, additional, Ursol, Grygoriy, additional, Vanasek, Jaroslav, additional, Varela, Mirta, additional, Vallejo, Marcela, additional, Vera, Luis, additional, Victorino, Ana-Paula, additional, Vlasek, Tomas, additional, Vynnychenko, Ihor, additional, Wang, Buhai, additional, Wang, Jie, additional, Wang, Kai, additional, Wu, Yilong, additional, Yamada, Kazuhiko, additional, Yang, Chih-Hsin, additional, Yokoyama, Takuma, additional, Yokoyama, Toshihide, additional, Yoshioka, Hiroshige, additional, Yumuk, Fulden, additional, Zambrano, Angela, additional, Zarba, Juan Jose, additional, Zarubenkov, Oleg, additional, Zemaitis, Marius, additional, Zhang, Li, additional, Zhang, Xin, additional, Zhao, Jun, additional, Zhou, Caicun, additional, Zhou, Jianying, additional, Zhou, Qing, additional, and Zippelius, Alfred, additional

Published
2019
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36. 'Implementación de la Unidad de Quimioterapia para el Desarrollo Hospital General 'Hosnag'

Author

Espol, Alvarado Moran, Jairon, Hoppe Zambrano, Angela, and Magallanes, Bessie

Subjects
HOSPITALES, RESUMEN ANALITICO
Abstract

En la actualidad el cáncer es una de las principales causas de muerte a nivel mundial, provocando cerca de 8 millones de muerte al año, para el 2025 se diagnosticarán 19.3 millones de nuevos casos, según la Organización Mundial de la Salud (OMS). Según esta organización registró que los tumores malignos de estómago, hígado, colorrectal, pulmón y próstata son los mas comunes en los hombres; en las mujeres el cáncer de mamas, colorrectal, cuello de útero, pulmón y estómago. Guayaquil Magíster en Gerencia Hospitalaria

Published
2016

37. Strain segmentario y longitudinal de pacientes cubanos con drepanocitosis.

Author

Torres Zambrano, Angela Jacqueline, Montenego Tobar, Danny Fernando, and Borges Moreno, Liudmila

Abstract

Copyright of Revista Habanera de Ciencias Médicas is the property of Universidad de Ciencias Medicas de La Habana and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2020

38. Pembrolizumab versus paclitaxel for previously treated, advanced gastric or gastro-oesophageal junction cancer (KEYNOTE-061): a randomised, open-label, controlled, phase 3 trial

Author

Shitara, Kohei, primary, Özgüroğlu, Mustafa, additional, Bang, Yung-Jue, additional, Di Bartolomeo, Maria, additional, Mandalà, Mario, additional, Ryu, Min-Hee, additional, Fornaro, Lorenzo, additional, Olesiński, Tomasz, additional, Caglevic, Christian, additional, Chung, Hyun C, additional, Muro, Kei, additional, Goekkurt, Eray, additional, Mansoor, Wasat, additional, McDermott, Raymond S, additional, Shacham-Shmueli, Einat, additional, Chen, Xinqun, additional, Mayo, Carlos, additional, Kang, S Peter, additional, Ohtsu, Atsushi, additional, Fuchs, Charles S, additional, Lerzo, Guillermo, additional, O'Connor, Juan Manuel, additional, Mendez, Guillermo Ariel, additional, Lynam, James, additional, Tebbutt, Niall, additional, Wong, Mark, additional, Strickland, Andrew, additional, Karapetis, Chris, additional, Goldstein, David, additional, Vasey, Paul, additional, Van Laethem, Jean-Luc, additional, Van Cutsem, Eric, additional, Berry, Scott, additional, Vincent, Mark, additional, Muller, Bettina, additional, Rey, Felipe, additional, Zambrano, Angela, additional, Guerra, Joaquin, additional, Krogh, Merete, additional, Baeksgaard, Lene, additional, Yilmaz, Mette, additional, Elme, Anneli, additional, Magi, Andrus, additional, Auvinen, Paivi, additional, Alanko, Tuomo, additional, Moehler, Markus, additional, Kunzmann, Volker, additional, Seufferlein, Thomas, additional, Thuss-Patience, Peter, additional, Hoehler, Thomas, additional, Haag, Georg, additional, Al-Batran, Salah-Eddin, additional, Castro, Hugo, additional, Lopez, Karla, additional, Aguilar Vasquez, Mynor, additional, Sandoval, Mario, additional, Lam, Ka On, additional, Cuffe, Sinead, additional, Kelly, Cathy, additional, Geva, Ravit, additional, Hubert, Ayala, additional, Beny, Alex, additional, Brenner, Baruch, additional, Giuseppe, Aprile, additional, Falcone, Alfredo, additional, Maiello, Evaristo, additional, Passalacqua, Rodolfo, additional, Montesarchio, Vincenzo, additional, Hara, Hiroki, additional, Chin, Keisho, additional, Nishina, Tomohiro, additional, Komatsu, Yoshito, additional, Machida, Nozumo, additional, Hironaka, Shuichi, additional, Satoh, Taroh, additional, Tamura, Takao, additional, Sugimoto, Naotaoshi, additional, Cho, Haruhiko, additional, Omuro, Yashushi, additional, Kato, Ken, additional, Goto, Masahiro, additional, Hyodo, Ichinosuke, additional, Yoshida, Kazuhiro, additional, Baba, Hideo, additional, Esaki, Taito, additional, Furuse, Junji, additional, Wan Mohammed, Wan Zamaniah, additional, Hernandez Hernandez, Carlos, additional, Casas Garcia, Juan, additional, Dominguez Andrade, Adriana, additional, Clarke, Katriona, additional, Hjortland, Geir, additional, Glenjen, Nils, additional, Kubiatowski, Tomasz, additional, Jacek, Jassem, additional, Wojtukiewicz, Marek, additional, Lazarev, Sergey, additional, Lancukhay, Yuri, additional, Afanasayev, Sergey, additional, Moiseyenko, Vladimir, additional, Kostorov, Vladimir, additional, Protsenko, Svetlana, additional, Shirinkin, Vadim, additional, Sakaeva, Dina, additional, Fadeeva, Natalia, additional, Yong, Wei Peng, additional, Ng, Chau Hsien Matthew, additional, Robertson, Barbara, additional, Rapaport, Bernardo, additional, Cohen, Graham, additional, Dreosti, Lydia, additional, Ruff, Paul, additional, Jacobs, Conrad, additional, Landers, Gregory, additional, Szpak, Waldemar, additional, Roh, Sang-Young, additional, Lee, Jeeyun, additional, Kim, Yeul Hong, additional, Chung, Hyun Cheol, additional, Alsina Maqueda, Maria, additional, Longo Munoz, Federico, additional, Cervantes Aguilar, Andres, additional, Aranda Aguilar, Enrique, additional, Garcia Alfonso, Pilar, additional, Rivera, Fernando, additional, Feliu Batle, Jaime, additional, Pazo Cid, Roberto, additional, Yeh, Kun-Huei, additional, Chen, Jen-Shi, additional, Chao, Yee, additional, Yen, Chia-Jui, additional, Kara, Oguz, additional, Yalcin, Suayib, additional, Hochhauser, Daniel, additional, Chau, Ian, additional, Benson, Al, additional, Shankaran, Veena, additional, Shaib, Walid, additional, Philip, Philip, additional, Sharma, Vivek, additional, Siegel, Robert, additional, Sun, Weijing, additional, Wainberg, Zev, additional, George, Ben, additional, Bullock, Andrea, additional, Myrick, Samuel, additional, Faruol, Josephine, additional, Siegel, Richard, additional, Larson, Timothy, additional, Becerra, Carlos, additional, Ratnam, Suresh, additional, Richards, Donald A., additional, and Riche, Stephen L., additional

Published
2018
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39. Pembrolizumab versus Ipilimumab in Advanced Melanoma

Author

Robert, Caroline, Schachter, Jacob, Long, Georgina V, Arance, Ana, Grob, Jean Jacques, Mortier, Laurent, Daud, Adil, Carlino, Matteo S, McNeil, Catriona, Lotem, Michal, Larkin, James, Lorigan, Paul, Neyns, Bart, Blank, Christian U, Hamid, Omid, Mateus, Christine, Shapira-Frommer, Ronnie, Kosh, Michele, Zhou, Honghong, Ibrahim, Nageatte, Ebbinghaus, Scot, Ribas, Antoni, Cebon, Jonathan, Hersey, Peter, Long, Georgina, Millward, Michael, Walpole, Euan, Höller, Christoph, Kehrer, Helmut, Richtig, Erika, Schmuth, Matthias, Baurain, Jean-François, Wolter, Pascal, Butler, Marcus, McWhirter, Elaine, Miller, Wilson, Petrella, Teresa, Acevedo, Alejandro, Caglevic, Christian, Morales, Luisa, Sanchez, Jesús, Yepes, Andres, Zambrano, Angela Regina, Avril, Marie-Francoise, Dutriaux, Caroline, Guilot, Bernard, Lacour, Jean-Phillippe, Leccia, Marie-Therese, Legoupil, Delphine, Lebbe, Celeste, Machet, Laurent, Berking, Carola, Loquai, Carmen, Mohr, Peter, Schadendorf, Dirk, Utikal, Jochen, Bar-Sela, Gil, Blank, Christian, Barrow, Catherine, Fitzharris, Bernie, Kersten, Christian, Nyakas, Marta, Straume, Oddbjørn, Berrocal, Alfonso, Cortes, Javier, Espinosa, Enrique, Lopez-Martin, Jose, Martin-Algarra, Salvador, Masucci, Giuseppe, Papworth, Karin, Ullenhag, Gustav, Brown, Ewan, Chao, David, Evans, Thomas, Middleton, Mark, Skaria, Sunil, Steven, Neil, Agarwala, Sanjiv, Bhatia, Shailender, Gangadhar, Tara, Gonzalez, Rene, Kumar, Pallavi, Kuzel, Timothy, Lutzky, Jose, O'Day, Steven, Perry, David, Pecora, Andrew, Puzanov, Igor, Slezak, Karen, Sznol, Mario, Tarhini, Ahmad, Weiss, Geoffrey, Laboratory of Molecullar and Cellular Therapy, Laboratory for Medical and Molecular Oncology, and Clinical sciences

Subjects
Adult, Male, medicine.medical_specialty, Skin Neoplasms, Adolescent, Programmed Cell Death 1 Receptor, Medizin, Phases of clinical research, Ipilimumab, Antineoplastic Agents, Pembrolizumab, Antibodies, Monoclonal, Humanized, Gastroenterology, Young Adult, Internal medicine, medicine, Humans, Adverse effect, Melanoma, Survival analysis, Aged, Aged, 80 and over, business.industry, Hazard ratio, Antibodies, Monoclonal, General Medicine, Middle Aged, medicine.disease, Survival Analysis, Surgery, Female, Talimogene laherparepvec, business, medicine.drug
Abstract

BACKGROUND: The immune checkpoint inhibitor ipilimumab is the standard-of-care treatment for patients with advanced melanoma. Pembrolizumab inhibits the programmed cell death 1 (PD-1) immune checkpoint and has antitumor activity in patients with advanced melanoma. METHODS: In this randomized, controlled, phase 3 study, we assigned 834 patients with advanced melanoma in a 1:1:1 ratio to receive pembrolizumab (at a dose of 10 mg per kilogram of body weight) every 2 weeks or every 3 weeks or four doses of ipilimumab (at 3 mg per kilogram) every 3 weeks. Primary end points were progression-free and overall survival. RESULTS: The estimated 6-month progression-free-survival rates were 47.3% for pembrolizumab every 2 weeks, 46.4% for pembrolizumab every 3 weeks, and 26.5% for ipilimumab (hazard ratio for disease progression, 0.58; P

Published
2015

40. Authenticating challenged e-mails: the problem of forgery

Author

Zambrano, Angela and Pellafone, Ricardo

Subjects
Microsoft Corp. -- Market research, Electronic mail systems -- Market research, Computer software industry -- Market research, Forgery, Marketing research, E-mail, Banking, finance and accounting industries
Abstract

This article addresses the problem of authenticating e-mails amidst allegations of forgery and provides a suggested framework for courts to use when these allegations are present., E-mail communication is an inescapable part of modern litigation. One marketing research firm that tracks e-mail statistics estimates that there are 2.9 billion e-mail accounts worldwide, 730 million of which [...]

Published
2011

41. PRESSURE AND PRESSURE DERIVATIVE ANALYSIS FOR NON-NEWTONIAN PSEUDOPLASTIC FLUIDS IN DOUBLE-POROSITY FORMATIONS

Author

Escobar, Freddy-Humberto, Zambrano, Angela-Patricia, Giraldo, Diana-Vanessa, and Cantillo-Silva, José-Humberto

Subjects
Behavior index, Interporosity flow, Power-law, Flujo interporoso, Fluxo interporoso, Comportamiento de flujo, Lei de potência, Coeficiente de almacenaje, Comportamento de fluxo, Doble porosidad, Ley de potencia, Fracture storativity, Porosidade dupla, Double-porosity, Coeficiente de armazenamento
Abstract

Non-Newtonian fluids are often used during various drilling, workover and enhanced oil recovery processes. Most of the fracturing fluids injected into reservoir-bearing formations possess non- Newtonian nature and these fluids are often approximated by Newtonian fluid flow models. In the field of well testing, several analytical and numerical models based on Bingham, pseudoplastic and dilatant non-Newtonian behavior, have been introduced in the literature to study their transient nature in porous media for a better reservoir characterization. Most of them deal with fracture wells and homogeneous formations. Well test interpretation is conducted via the straight-line conventional analysis or type-curve matching. Only a few studies consider the pressure derivative analysis. However, there is a need for a more practical and accurate way of characterizing such systems. So far, there is no methodology to characterize heterogeneous formation bearing non-Newtonian fluids through well test analysis. In this study, an interpretation methodology using the pressure and pressure derivative log-log plot is presented for non-Newtonian fluids in naturally fractured formations. The dimensionless fracture storativity ratio, omega, and interporosity flow parameter, lambda, are obtained from characteristics points found on such plot. The developed equations and correlations are successfully verified by their application only to synthetic well test data since no actual field data are available. A good match is found between the results provided by the proposed technique and the values used to generate the simulated data. RESUMEN Los fluidos no Newtonianos se usan a menudo en varios procesos de perforación, trabajo a pozos y actividades de recobro mejorado. La mayoría de los fluidos de fracturamiento inyectados en los yacimientos que contienen hidrocarburos se comportan no Newtoniamente y, sin embargo, estos fluidos comúnmente se representan en los modelos como modelos fluidos Newtonianos. En el campo de pruebas de presión, se han desarrollado varios modelos numéricos y analíticos que tienen en cuenta el comportamiento no Newtoniano Bingham, pseudoplá;stico y dilatante, para estudiar la naturaleza transitoria de estos fluidos en una mejor caracterizacion del yacimiento. Se han propuesto varios modelos numericos y analiticos para estudiar el comportamiento transitorio de los fluidos no Newtonianos en medios porosos. La mayoría de ellos tratan pozos fracturados y formaciones homogeneas y la interpretacion de los datos de presion se conduce mediante el metodo convencional de la linea recta o ajuste por curvas tipo. Solamente unos pocos estudios consideran analisis con la derivada de presion. Hasta ahora no existe ninguna metodologia para caracterizar formaciones heterogeneas mediante pruebas de presion. Sin embargo, hay necesidad de una forma mas practica y exacta de caracterizar estos sistemas. Por lo tanto, este trabajo presenta una metodologia de interpretacion usando la curva logaritmica de presion y derivada de presion para fluidos no Newtonianos en formaciones naturalmente fracturadas de modo que el coeficiente adimensional de almacenaje, omega, y el parametro de flujo interporoso, lambda, se obtienen de puntos caracteristicos encontrados en el grafico log-log de la presion y derivada de presión. Las ecuaciones y correlaciones desarrolladas se verificaron satisfactoriamente mediante su aplicación solo a pruebas de presion sinteticas ya que no existen datos reales reportados en la literatura. Se hallo un buen ajuste entre los resultados obtenidos mediante la metodologia propuesta y los valores usados para generar la simulación. RESUMO O fluidos não Newtonianos são usados frequentemente em vá;rios processos de perfuração, trabalho em poços e atividades de recuperação melhorada. A maioria dos fluidos de fraturamento injetados nas jazidas que contêm hidrocarbonetos se comportam não Newtoniamente e, não obstante, estes fluidos são representados normalmente nos modelos como modelos fluidos Newtonianos. No campo de provas de pressão, foram desenvolvidos vá;rios modelos numéricos e analíticos que consideram o comportamento não Newtoniano Bingham, pseudoplá;stico e dilatante para estudar a natureza transitória destes fluidos para uma melhor caracterização da jazida. Foram propostos vá;rios modelos numéricos e analíticos para estudar o comportamento transitório dos fluidos não Newtonianos em meios porosos. A maioria deles trata poços fraturados e formações homogêneas e a interpretação dos dados de pressão é conduzida mediante o método convencional da linha reta ou ajuste por curvas tipo. Apenas uns poucos estudos consideram aná;lise com a derivada de pressão. Até agora não existe nenhuma metodologia para caracterizar formações heterogêneas mediante provas de pressão. Porém, existe a necessidade de uma forma mais prá;tica e exata de caracterizar estes sistemas. Por tanto, este trabalho apresenta uma metodologia de interpretação usando a curva logarítmica de pressão e derivada de pressão para fluidos não Newtonianos em formações naturalmente fraturadas, de modo que o coeficiente adimensional de armazenamento, ômega, e o parâmetro de fluxo interporoso, lambda, são obtidos de pontos característicos encontrados no grá;fico log-log da pressão e da derivada de pressão. As equações e correlações desenvolvidas foram consideradas satisfatórias mediante sua aplicação individual a provas de pressão sintéticas, já; que não existem dados reais registrados na literatura. Encontrou-se um bom ajuste entre os resultados obtidos mediante a metodologia proposta e os valores usados para gerar a simulação.

Published
2011

43. Modelo de backtesting fe tester para la creación de estrategias de inversión y su aplicación a la estructuración de un fondo mutuo de inversión

Author

Moreno Buitrago, Giovanny / Director, Tenjo Leal, Julian Javier, Ruiz Zambrano, Angela Patricia, Moreno Buitrago, Giovanny / Director, Tenjo Leal, Julian Javier, and Ruiz Zambrano, Angela Patricia

Abstract

Este trabajo tiene como tema un modelo de backtesting para estrategias de especulación que permite estructurar fondos mutuos de inversión; y en él se busca mostrar al lector el desarrollo de este modelo, cómo se generan las estrategias a partir de los conceptos del análisis técnico y cuál es la estructura que debe tener un fondo mutuo de inversión para hacer aplicable este modelo. El backtesting es una herramienta del análisis técnico sistémico que permite evaluar a partir de datos históricos estrategias especulativas, y su automatización se realiza con ayuda de software. El modelo FE Tester se diseño en MS Excel y las estrategias utilizadas están soportadas por los indicadores técnicos más populares en el mercado. Como aporte académico desde el enfoque de la ingeniería financiera, se evalúa la estructuración de un fondo mutuo de inversión, por ser una figura que fomenta el ahorro, la inversión en el mercado financiero y el acceso a capitales pequeños. Con base en las estrategias evaluadas en el modelo se hace la estructuración de un portafolio que responda a las necesidades de los trabajadores que colaboraron para la investigación., This investigation has as main topic a backtesting model for speculative strategies that leads to the structure of a mutual investment fund, in search of explaining the development of the model, how to create the strategies based on technical analysis concepts and what is the ideal structure of a mutual investment fund in order to take to the real life the model. Backtesting is a tool of systemic technical analysis to evaluate strategies using historical data, and its automation is done with software support. The FE Tester model was designed in MS Excel, and the strategies on it, were supported by the most popular technical indicators in the market. As an academic plus from financial engineering, the structuring of an investment mutual fund is evaluated, because of its saving nature, investment in financial markets and the opportunity for small amounts. Based on the strategies used in the model a portfolio is created, taking into count the needs of the employees who collaborate in this investigation.

Published
2014

47. PUTTING THE CART BEFORE THE HORSE: SHOULD A COURT CERTIFY A CLASS OF RESIDENTIAL CONSUMERS SEEKING A DECLARATION THAT THE CONSUMERS — IF THEY LATER CHOOSE — ARE ENTITLED TO RESCIND FOR A TILA VIOLATION?

Author

Zambrano, Angela C. and Barnett, Kent

Subjects
CONSUMERS, RESCISSION (Law), LOANS, MONEYLENDERS, CONTRACTS, DECLARATION of intention, ACTIONS & defenses (Law), OBLIGATIONS (Law), COMPLAINTS (Civil procedure)
Abstract

The article discusses the implications of a court certification on a class of residential consumers seeking declaration if they choose to rescind for a Truth in Lending Act (TILA) violation. A review of the arguments in class actions made by consumers seeking for declaration on individual loan transactions based on the alleged TILA. Common arguments raised by lenders and consumers are researched. TILA class actions limitations are addressed emphasizing on rescission of residential loan for consumer and lender. Improved statutory damages are also discussed.

Published
2008

48. COORDINATING RELATED BANKING CASES ON AN INTRA-STATE BASIS.

Author

Zambrano, Angela C. and Hartmann, Michelle

Subjects
BANKING laws, BANKING industry, COMMERCIAL law, FINANCIAL institutions, CIVIL procedure, ACTIONS & defenses (Law), CLASS actions, STATUTES
Abstract

The article examines the state coordination rules related to banking cases at the different states in the U.S. Included are the Rule 213 of the Pennsylvania Rules of Civil Procedure, Rule 32L of the Oregon Rules of Civil Procedure and the Multiple Claimant Litigation Act of Virginia. Provisions of the Senate Bill 5, The Class Action Fairness Act of 2005 (CAFA) were taken into account. Brief description and information about the constitutional support for the state coordination is further presented.

Published
2007

50. Practicing gratitude: Lessons from my mother.

Author

Zambrano, Angela C.

Subjects
*GRATITUDE, *WORKING mothers, *MOTHER-daughter relationship, *WORK-life balance, *WOMEN lawyers, *EXPERIENCE, *CHILDREN of single mothers, *ATTITUDE (Psychology)
Abstract

The article discusses gratitude and the challenges that are associated with being a working mother in the legal profession in relation to work-life balance, and it mentions the author's personal experiences as the child of a single mother and as a working mother herself. Career satisfaction and flexible working hours are examined, along with mother-daughter relations and the views of an American female attorney.

Published
2018

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