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217 results on '"Zaidenstein, Ronit"'

17. Clinical characteristics and molecular subtyping of Vibrio vulnificus illnesses, Israel

Author

Zaidenstein, Ronit, Sadik, Chantal, Lerner, Larisa, Valinsky, Lea, Kopelowitz, June, Yishai, Ruth, Agmon, Vered, Parsons, Michele, Bopp, Cheryl, and Weinberger, Miriam

Subjects
Infection -- Health aspects, Infection -- Risk factors, Heart diseases -- Health aspects, Heart diseases -- Risk factors, Medical research -- Health aspects, Medicine, Experimental -- Health aspects
Abstract

Vibrio vulnificus, a gram-negative bacterium of the family Vibrionaceae, is a worldwide inhabitant of salt water (1-3). V. vulnificus biotypes 1 and 2 are capable of causing severe human infection, [...]

Published
2008

18. Fatal Rickettsia conorii subsp. israelensis infection, Israel

Author

Weinberger, Miriam, Keysary, Avi, Sandbank, Judith, Zaidenstein, Ronit, Itzhaki, Avi, Strenger, Carmela, Leitner, Moshe, Paddock, Christopher D., and Eremeeva, Marina E.

Subjects
Rickettsia -- Health aspects, Rickettsial diseases -- Risk factors, Rickettsial diseases -- Diagnosis, Rickettsial diseases -- Care and treatment, Rickettsial diseases -- Case studies
Abstract

Underdiagnosis of fatal spotted fever may be attributed to nonspecific clinical features and insensitive acute-phase serologic studies. We describe the importance of molecular and immunohistochemical methods in establishing the postmortem [...]

Published
2008

19. Patient-Reported Outcome Measures After Hospitalization During the COVID-19 Pandemic: A Survey Among COVID-19 and Non-COVID-19 Patients

Author

Elkan,Matan, Dvir,Ayana, Zaidenstein,Ronit, Keller,Maly, Kagansky,Dana, Hochman,Chen, Koren,Ronit, Elkan,Matan, Dvir,Ayana, Zaidenstein,Ronit, Keller,Maly, Kagansky,Dana, Hochman,Chen, and Koren,Ronit

Abstract

Matan Elkan,1 Ayana Dvir,2 Ronit Zaidenstein,1,3 Maly Keller,1 Dana Kagansky,1 Chen Hochman,1 Ronit Koren1,3 1Department of Internal Medicine A, Shamir (Assaf Harofeh) Medical Center, Zerifin, Israel; 2Intensive Care Unit, Shamir (Assaf Harofeh) Medical Center, Zerifin, Israel; 3Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, IsraelCorrespondence: Matan ElkanDepartment of Internal Medicine A, Shamir (Assaf Harofeh) Medical Center, Zerifin, 7030000, IsraelTel +972-8-977-9242Fax + 972-8-977-9243Email matanelkan@gmail.comBackground: Many people recovering from COVID-19 suffer from long-term sequelae. The objective of this study was to assess health-related quality of life (HRQoL) in COVID-19 patients several months after discharge.Methods: We conducted a retrospective cross-sectional case–control study on COVID-19 and non-COVID-19 pneumonia patients admitted to Shamir Medical Center, Israel (03– 07/2020). In the months following discharge, patients were invited to participate in a survey and fill the RAND-36 questionnaire. Patients’ characteristics and comorbidities were extracted from electronic charts.Results: Among 66 COVID-19 participants, the median age was 58.5 (IQR 49.8– 68.3), 56.1% were female, and 36.4% were obese. The median length of stay was 7 days (IQR 4– 10). Patient-reported outcome measures were reported at a median follow-up of 9-months (IQR 6– 9). Pain, general health, vitality, and health change had the lowest scores (67.5, 60, 57.5, and 25, respectively). Matching to patients hospitalized with pneumonia due to other pathogens was performed on 42 of the COVID-19 patients. Non-COVID-19 patients were more frequently current or past smokers (50% vs 11.9%, p < 0.01) and suffered more often from chronic lung disease (38.1% vs 9.5%, p = 0.01). The score for health change was significantly lower in the COVID-19 group (25 vs 50, p < 0.01).Conclusion: Post COVID-19 patients continue to suffer from an assortment of symptoms and p

Published
2021

23. Antimicrobial use for asymptomatic bacteriuria—First, do no harm

Author

Shpunt, Yana, primary, Estrin, Inna, additional, Levi, Yossef, additional, Saadon, Hodaya, additional, Ben-Yossef, Galit, additional, Goldshtein, Lili, additional, Klafter, Dan, additional, Zilberman-Itskovich, Shani, additional, Ben-David, Debby, additional, Katz, David E., additional, Lazarovitch, Tsillia, additional, Zaidenstein, Ronit, additional, and Marchaim, Dror, additional

Published
2020
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26. Randomised trial of high-dose isosorbide dinitrate plus low-dose furosemide versus high-dose furosemide plus low-dose isosorbide dinitrate in severe pulmonary oedema

Author

Cotter, Gad, Metzkor, Einat, Kaluski, Edo, Faigenberg, Zwi, Miller, Rami, Simovitz, Avi, Shaham, Ori, Marghitay, Doron, Koren, Maya, Blatt, Alex, Moshkovitz, Yaron, Zaidenstein, Ronit, and Golik, Ahuva

Subjects
Pulmonary edema -- Drug therapy, Furosemide -- Evaluation, Isosorbide dinitrate -- Evaluation, Vasodilators -- Health aspects
Published
1998

28. 2043. The “Resistance Calculator”: Refining Empiric Practices of Antimicrobials Prescription in the Era of Widespread Resistance

Author

Zilberman-Itskovich, Shani, primary, Strul, Nathan, additional, Chedid, Khalil, additional, Shorbaje, Akram, additional, Lazarovitch, Tsilia, additional, Zohar, Yarden, additional, Razin, Hadas, additional, Low, Amitai, additional, Strulovici, Ariela, additional, Katz, David, additional, Dhar, Sorabh, additional, Milton Parsons, Leo, additional, Ramos-Mercado, Abdiel, additional, Zaidenstein, Ronit, additional, Martin, Emily T, additional, and Marchaim, Dror, additional

Published
2019
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36. Long QT and death in hospitalized patients with acute exacerbation of chronic obstructive pulmonary disease is not related to electrolyte disorders

Author

Zilberman-Itskovich,Shani, Rahamim,Eldad, Tsiporin-Havatinsky,Faina, Ziv-Baran,Tomer, Golik,Ahuva, Zaidenstein,Ronit, Zilberman-Itskovich,Shani, Rahamim,Eldad, Tsiporin-Havatinsky,Faina, Ziv-Baran,Tomer, Golik,Ahuva, and Zaidenstein,Ronit

Abstract

Shani Zilberman-Itskovich,1 Eldad Rahamim,1 Faina Tsiporin-Havatinsky,1 Tomer Ziv-Baran,2 Ahuva Golik,1 Ronit Zaidenstein11Internal Medicine Department A, Assaf-Harofeh Medical Center, Zerifin, Israel; 2School of Public Health, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, IsraelObjectives: COPD is the fourth-leading cause of mortality worldwide. Prolonged QTc has been found to be a long-term negative prognostic factor in ambulatory COPD patients. The aim of this study was to evaluate the extent of prolonged-QTc syndrome in COPD patients upon admission to an internal medicine department, its relationship to hypomagnesemia, hypokalemia, and hypocalcemia, and the effect of COPD treatment on mortality during hospital stay.Methods: This prospective cohort study evaluated COPD patients hospitalized in an internal medicine department. The study evaluated QTc, electrolyte levels, and known risk factors during hospitalization of COPD patients.Results: A total of 67 patients were recruited. The median QTc interval was 0.441 seconds and 0.434 seconds on days 0 and 3, respectively. Prolonged QTc was noted in 35.8% of patients on admission and 37.3% on day 3 of hospitalization. The median QTc in the prolonged-QTc group on admission was 0.471 seconds and in the normal-QTc group 0.430 seconds. There was no significant difference in age, sex, electrolyte levels, renal function tests, or blood gases on admission between the two groups. Mortality during the hospital stay was significantly higher in the prolonged-QTc group (3 deaths, 12%) than in the normal QTc group (no deaths) (P=0.04). A subanalysis was performed, removing known causes for prolonged QTc. We found no differences in age, electrolytes, or renal functions. There was a small but significant difference in bicarbonate levels.Conclusion: Our findings demonstrated that there was no correlation between QTc prolongation in hospitalized COPD patients and electrolyte levels, comorbidities, or relevant medications

Published
2019

37. Haemophilus influenzae infections in pregnancy: a retrospective, nested case–control study.

Author

Zilberman-Itskovich, Shani, Oren, Chen, Zaidenstein, Ronit, Wiener, Yifat, Lazarovitch, Tsillia, Rokney, Assaf, Ron, Merav, Agmon, Vered, and Marchaim, Dror

Subjects
NEONATAL sepsis, HAEMOPHILUS influenzae, HAEMOPHILUS diseases, PREGNANCY, CASE-control method
Abstract

Sepsis is one of the major causes of maternal deaths (Morgan and Roberts [6]). Currently, there is no routine screening methodology for diagnosing I H. influenzae i carriage during pregnancy, despite only minor lower rates of invasive neonatal infections compared to group b streptococci (GBS): i.e. 3/100,000 versus 4/100,000 for I NTHi i and GBS, respectively (Collins et al. [2]). Invasive I H. i I influenzae i bloodstream infections occurred in 63% of case-patients, and 32% of infections were polymicrobial. Overall, 19 patients with I H. i I influenzae i maternal infection were enrolled (Table 1) and matched to 57 control patients. [Extracted from the article]

Published
2022
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38. 1204. The MDR Upon Admission Score for Shortening Time to Initiation of Appropriate Antimicrobial Therapy in the Era of Widespread Resistance to Antimicrobials

Author

Chedid, Khalil, primary, Zilberman-Itskovich, Shani, additional, Shorbaje, Akram, additional, Martin, Emily T, additional, Lazarovitch, Tsilia, additional, Zaidenstein, Ronit, additional, Dadon, Mor, additional, Saadon, Hodaya, additional, Maya, Tal, additional, and Marchaim, Dror, additional

Published
2018
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41. Towards a Definition for Health Care–Associated Infection

Author

Friedman, N Deborah, primary, Levit, Dana, additional, Taleb, Eyal, additional, Marcus, Gil, additional, Michaeli, Leah, additional, Broide, Mor, additional, Mengesha, Bethlehem, additional, Zaidenstein, Ronit, additional, Lazarovitch, Tsilia, additional, Dadon, Mor, additional, Kaye, Keith S, additional, and Marchaim, Dror, additional

Published
2018
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42. The epidemiology of carbapenem resistant Enterobacterspp: A case–case–control matched analysis

Author

Cohen Mendel, Leore, Amity, Keren, Katz, David E., Lazarovitch, Tsilia, Zaidenstein, Ronit, and Marchaim, Dror

Abstract

AbstractA case–case–control investigation (216 patients) examined the risk factors and outcomes of carbapenem-resistant Enterobacter(CR-En) acquisition. Recent exposure to fluoroquinolones, intensive care unit (ICU) stay, and rapidly fatal McCabe condition were independent predictors for acquisition. Acquiring CR-En was independently associated with discharge to a long-term care facility after being admitted from home.

Published
2021
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43. Therapeutic Management of Pseudomonas aeruginosa Bloodstream Infection Non-Susceptible to Carbapenems but Susceptible to “Old” Cephalosporins and/or to Penicillins

Author

Zaidenstein, Ronit, primary, Miller, Asaf, additional, Tal-Jasper, Ruthy, additional, Ofer-Friedman, Hadas, additional, Sklarz, Menachem, additional, Katz, David, additional, Lazarovitch, Tsillia, additional, Lephart, Paul, additional, Mengesha, Bethlehem, additional, Tzuman, Oran, additional, Dadon, Mor, additional, Daniel, Chen, additional, Moran-Gilad, Jacob, additional, and Marchaim, Dror, additional

Published
2018
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44. Antimicrobial use for asymptomatic bacteriuria—First, do no harm

Author

Shpunt, Yana, Estrin, Inna, Levi, Yossef, Saadon, Hodaya, Ben-Yossef, Galit, Goldshtein, Lili, Klafter, Dan, Zilberman-Itskovich, Shani, Ben-David, Debby, Katz, David E., Lazarovitch, Tsillia, Zaidenstein, Ronit, and Marchaim, Dror

Abstract

AbstractObjective:Administration of antimicrobials to patients with asymptomatic bacteriuria (ASB) is a common error that can lead to worse outcomes. However, controlled analyses quantifying the commonality and impact of this practice are lacking. We analyzed the independent predictors for antimicrobials misuse in ASB and quantified the impact of this practice on clinical outcomes.Design:Retrospective case-control and cohort analyses for calendar year 2017.Setting:Tertiary-care, university-affiliated medical center.Patients:The study included adult (>18 years) patients with positive urine culture. Pregnant women, renal transplant recipients, and patients who underwent urologic procedures were excluded.Methods:ASB was determined according to US Centers for Disease Control and Prevention (CDC) criteria. Multivariable logistic regression models were constructed to analyze predictors and outcomes associated with antimicrobial use for patients with ASB.Results:The study included 1,530 patient-unique positive urine cultures. Among these patients, 610 patients (40%) were determined to have ASB. Of the 696 isolates, 219 (36%) were multidrug-resistant organisms (MDROs). Also, 178 (29%) patients received antimicrobials specifically due to the ASB. Independent predictors for improper administration of antimicrobials were dependent functional status (adjusted odds ratio [aOR], 2.3; 95% CI, 1.4–3.6) and male sex (aOR, 2; 95% CI, 1.25–2.6). Use of antimicrobials was independently associated with re-hospitalizations (aOR, 1.7; 95% CI, 1.1–2.6) and later, acute Clostridioides difficile infections (CDI) in the following 90 days (aOR, 4.5; 95% CI, 2–10.6).Conclusions:ASB is a common condition, frequently resulting from an MDRO. Male sex and poor functional status were independent predictors for mistreatment, and this practice was independently associated with rehospitalizations and CDI in the following 90 days.

Published
2021
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50. Intra-abdominal Infections: The Role of Anaerobes, Enterococci, Fungi, and Multidrug-Resistant Organisms

Author

Marcus, Gil, primary, Levy, Samuel, additional, Salhab, Ghaleb, additional, Mengesha, Bethlehem, additional, Tzuman, Oran, additional, Shur, Shira, additional, Burke, Erica, additional, Mayeda, Rebecca Cruz, additional, Cochavi, Lior, additional, Perluk, Idan, additional, Zaidenstein, Ronit, additional, Lazarovitch, Tsilia, additional, Dadon, Mor, additional, and Marchaim, Dror, additional

Published
2016
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