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A Trombe wall-heating system is used to absorb solar energy to heat buildings. Different parameters affect the system performance for optimal heating. This study evaluated the performance of four machine learning algorithms—linear regression, k-nearest neighbors, random forest, and decision tree—for predicting the room temperature in a Trombe wall system. The accuracy of the algorithms was assessed using R² and root mean squared error (RMSE) values. The results demonstrated that the k-nearest neighbors and random forest algorithms exhibited superior performance, with R² and RMSE values of 1 and 0. In contrast, linear regression and decision tree showed weaker performance. These findings highlight the potential of advanced machine learning algorithms for accurate room temperature prediction in Trombe wall systems, enabling informed design decisions to enhance energy efficiency.

Abstract Background Knee osteoarthritis causes pain and disability in many people worldwide, for which no definitive treatment has yet been proposed. In this study, we investigated the safety and efficacy of placental mesenchymal stromal cells-derived extracellular vesicles in patients with knee osteoarthritis. Methods This triple-blind, randomized clinical trial included patients suffering from bilateral knee osteoarthritis with grade 2 or 3. The knees of each patient were randomized to intervention and control. For the intervention knee, 5 cc of placental mesenchymal stromal cells-derived extracellular vesicles were injected, and for the control knee, 5 cc of normal saline was injected. The patients’ symptoms were evaluated before the intervention and 2 and 6 months after the intervention using VAS, WOMAC questionnaire, and Lequesne index. MRI was performed before the intervention and 6 months after the intervention to evaluate retropatellar and tibiofemoral cartilage volume, medial and lateral meniscal disintegrity, ACL injury, and effusion-synovitis. Results 62 knees (31 patients) were enrolled in this study. There were 31 knees as intervention and 31 knees as control. Finally, the data of 58 knees (29 patients) were analyzed, including 28 women and 1 man. The mean age of the patients was 55.38 ± 6.07 years. No statistically significant difference was detected between the two groups in clinical outcomes (including VAS, WOMAC, and Lequesne scores) before treatment and 2 and 6 months after treatment. Also, no statistically significant difference was detected between the two groups in MRI findings before treatment and 6 months after treatment. No systemic complications or severe local reactions occurred in the patients. Conclusion A single intra-articular injection of placental mesenchymal stromal cells-derived extracellular vesicles (5 cc, 7 × 109 particles/cc) is safe, but does not improve clinical symptoms or MRI findings in knee osteoarthritis beyond placebo. The protocol of this study was approved on 11 May 2022 with registration number IRCT20210423051054N1.

This study aims to predict the solubility of salicylic acid in 13 different solvents, such as methanol, water, ethanol, ethyl acetate, PEG 300, 1,4-dioxane, 1-propanol, and others, given the significance of salicylic acid in the pharmaceutical industry. based on machine learning has been studied. In this study, 6 machine learning algorithms including neural network, linear regression, logistic regression, decision tree, random forest and kNN (k- Nearest Neighbors) were used. The comparison between the predictions of these algorithms and experimental data highlights the accuracy of predicting the solubility of salicylic acid for 217 samples based on 15 variables (13 solvents, temperature, and pressure). Based on the results of this study, the lowest total error (difference between experimental and predicted values) was 0.00016835 related to the random forest algorithm, and the highest value was 0.024768 related to k-Nearest Neighbors.

Abstract A hybrid system was designed and synthesized through reacting modified halloysite (Hal-Cl) with Schiff base (DAB-PC) and applied as catalytic support for anchoring Pd NPs to afford Pd@Hal-DAB-PC catalyst. The resultant material was well identified by various analyses including Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction patterns (XRD), thermogravimetric analysis (TGA), field-emission scanning electron microscopy (FE-SEM), energy-dispersive X-ray spectroscopy (EDS), transmission electron microscopy (TEM), and inductively coupled plasma-optical emission spectrometry (ICP-OES) and revealed outstanding catalytic activity in the Sonogashira reaction in aqueous media. Also, This nanocatalyst was simply collected and recycled up to six runs with a slight drop in efficiency, indicating the durability of Pd@Hal-DAB-PC.

Since the Almighty God mentions the dominance of Men over Women in the Holy Quran ( Nisa’, 34) the concept of “domination” has been on the focus of many commentators and interpreters. From the perspective of the family, the very initial institution in human life, the issue of Men’s domination would be well considered within the context of family. The present study, having a Shiite jurisprudence perspective, seeks to find a reasonable explanation to this. The concept of domination can well be explained based on "Human Interests" in Shiite ideology. According to this ideology there is compatibility between Men’s domination and Human Fitrah (essence), by and large, family consolidation and maintenance. The issue of Gender differences, consequently, should be considered upon the explanation of one’s right and duty.

Quran, on different occasions, has condemned the popular culture of the era of ignorance. Notions of vanity, the status of ignorant rules, and prejudice are the constituent components of this culture. Analysis of customs and laws that govern the life of modern man reveal the components of ignorance in the present age of modern societies such as fear of Islam, humanism, Europeanism, usury, human trafficking, consumption of psychotropic drugs, and promotion of unsuitable clothing. Considering the moral teachings of Islam, ways to remove components of moral ignorance are identified in Islamic moral and ethical resources. Accordingly, this study also uses content analysis to identify components of ignorance in modern societies and by reflecting on the Quran and the Makarem Al-Akhlaq Prayer, it has mentioned some of the ways to deal with the culture of ignorance such as virtue vocation, self-construction and practice of humility, following the mind and the narrative rationales, moderation etc.

In Letter 47 of Nahjolbalaghe, Imam Ali (PBUH) introduces three important issues including the fear of God, order in affairs and peace among people. The term “order in affairs” has become synonymous in recent centuries with individual order – that is, the placement of every object in its position. But based on the evidence available in the context of the letter including sensitive situations in the period, addressees of the letter, literal and applied meanings of order at the time and other expressions used by Imam (PBUH), it seems that another meaning was originally meant by “order in affairs”. In a lexical study, it can be figured out that the word order had some social sense of “consistency” in earlier periods while some recent dictionaries consider an individual meaning for it in addition to the social meaning. The synthesis of different views by interpreters and some translators of Nahj al-Balagha concerning the term “order in affairs” points to the social sense of “unity and consistency”. Applications of the words “order” and “affairs” in Nahj al-Balagha and other texts highlight the sense of “consistency” for the word order as its original meaning and the senses of “work”, “diversity” and “management” for the word affairs. The views of some contemporaries about the term “order in affairs” suggest that the meaning of unity for order is the common ground. However, some have pointed to the sense of keeping up the government/ regime as the accurate meaning of affairs. Finally, it can be concluded that the term “order in affairs” in this quote from Imam Ali (PBUH) suggests his emphasis on the concept of unity.

Background: Knee osteoarthritis causes pain and disability in many people worldwide, for which no definitive treatment has yet been proposed. In this study, we investigated the safety and efficacy of placental mesenchymal stromal cells-derived extracellular vesicles in patients with knee osteoarthritis. Methods: This triple-blind, randomized clinical trial included patients suffering from bilateral knee osteoarthritis with grade 2 or 3. The knees of each patient were randomized to intervention and control. For the intervention knee, 5 cc of placental mesenchymal stromal cells-derived extracellular vesicles were injected, and for the control knee, 5 cc of normal saline was injected. The patients' symptoms were evaluated before the intervention and 2 and 6 months after the intervention using VAS, WOMAC questionnaire, and Lequesne index. MRI was performed before the intervention and 6 months after the intervention to evaluate retropatellar and tibiofemoral cartilage volume, medial and lateral meniscal disintegrity, ACL injury, and effusion-synovitis. Results: 62 knees (31 patients) were enrolled in this study. There were 31 knees as intervention and 31 knees as control. Finally, the data of 58 knees (29 patients) were analyzed, including 28 women and 1 man. The mean age of the patients was 55.38 ± 6.07 years. No statistically significant difference was detected between the two groups in clinical outcomes (including VAS, WOMAC, and Lequesne scores) before treatment and 2 and 6 months after treatment. Also, no statistically significant difference was detected between the two groups in MRI findings before treatment and 6 months after treatment. No systemic complications or severe local reactions occurred in the patients. Conclusion: A single intra-articular injection of placental mesenchymal stromal cells-derived extracellular vesicles (5 cc, 7 × 109 particles/cc) is safe, but does not improve clinical symptoms or MRI findings in knee osteoarthritis beyond placebo. The protocol of this study was approved on 11 May 2022 with registration number IRCT20210423051054N1. [ABSTRACT FROM AUTHOR]