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Background: Danyikangtai powder, a Traditional Chinese Medicine (TCM) formula, shows promise to become a novel drug candidate for the simultaneous treatment of chronic cholecystitis and chronic pancreatitis. However, the pharmacokinetic behavior of Danyikangtai powder remains unclear. Objective: We investigated the comparative pharmacokinetics of four flavonoids in rats after oral administration of Danyikangtai powder and three compatibilities. Materials and Methods: The comparative pharmacokinetics was studied by ultra-performance liquid chromatography-tandem mass spectrometry (UPLC–MS/MS). Chromatographic separation was performed on a Universil XB-C18 column with a gradient mobile phase containing 0.1% (v/v) aqueous formic acid and acetonitrile. All analytes and internal standard were quantitated in the multiple reaction monitoring modes with a positive electrospray ionization interface. Results and Discussion: Danyikangtai powder and Scutellariae radix have similar pharmacokinetic behaviors in rats after oral administration. However, the elimination of four flavonoids in rats after oral administration of Danyikangtai powder was accelerated, which was possibly related to the reduction of the potential hepatotoxicity of Scutellariae radix. The varying degrees of change in pharmacokinetic parameters after oral administration of different herb combinations suggested that herb–herb interactions occurred in vivo. Conclusions: This study will be helpful to reveal the safety, rational and mechanism of Danyikangtai powder formula compatibility, thereby providing pre-clinical research data for its new drug development and guidance for its rational clinical application.

Compared with the quantum gate circuit model, the measurement-based quantum computing model provides an alternative way to realize universal quantum computation, and relevant contents have been greatly enriched after nearly two decades of research and exploration. In this article, we review the research history and status of the measurement-based quantum computing model. First, we briefly introduce the basic theories of this model, including the concept and working principles of quantum graph states as resource states, the model’s computational universality and classical simulation methods, and relevant applications in the field of quantum information processing such as designing quantum algorithms and fault-tolerant error correction schemes. Then, from the perspective of quantum physical properties, which include the specific roles of quantum entanglement, contextuality, quantum correlations, symmetry-protected topological order, and quantum phases of matter as computing resources, the close relationship between measurement-based quantum computing model and quantum many-body system is presented. For example, a type of measurement-based computing model for exploiting quantum correlations can show a quantum advantage over the classical local hidden variable models, or certain symmetry-protected topological order states enable the universal quantum computation to be conducted by using only the measurements of single-qubit Pauli operators. Next, a variety of different technical routes and experimental progress of realizing the measurement-based quantum computing model are summarized, such as photonic systems, ion traps, superconducting circuits, etc. These achievements in various physical areas lay the foundation for future scalable and fault-tolerant quantum computers. Finally, we discuss and prospect the future research directions in this field thereby inspiring readers to further study and explore the relevant subjects.

Analysis of the structure characteristics of the high-rise building, through the instrument observation, obtains each observation point’s total of subsidence and maximum subsidence, found no settlement of building site. Using the fi-nite element software for structural modeling, modal analysis shows that the quality of structural system, the stiffness is more evenly distributed the structure of the torsional capacity to meet the requirements. The model input Tianjin wave, analyzes the dynamic characteristics of the model, the results showed that: structure below the middle and lower classes, with the building height decreases, the horizontal displacement of reducing the magnitude of the structure of the middle and upper classes, with the building height increases, the horizontal displacement increases, a lesser extent; frame - shear wall structure, shear walls there are substantial limitations in the bottom of the lateral displacement, compared with the upper structure of the lateral displacement limit capacity.

The ligand [1,2-bis(4-pyridinecarboxamido)ethane] (L) and the coordination polymer |[Cu(L)2(H2O)]-(NO3)2·6H2O|·(1) haw been synthesized and characterized by ER and 1H NMR spectra. Their molecular structures and the packing of 1 have been determined by single-crystal X-ray diffraction analysis. The Cu(n) in 1 is bridged by two ligands forming an infinite one-dimensional chain like structure and L in 1 adopts a different conformation from its free state. 1 belongs to monoclinic, space group P21/n, a = 1.2896(3) nm, b = 1.2552(8) nm, c = 2.2903(19) nm, β = 93.04(5)°, Z = 4, V = 3.702(4) nm3. The TG and DTG experiments showed that the uncoordinated H2O can be removed at low temperature by heating, and it does not decompose until 250 °C.

We theoretically investigate the additional correction to the Casimir effect due to the change of dielectric constant with temperature, which is different from the previous research that have widely taken dielectric constants of materials as a value independent of temperature. It is found that such a correction can go beyond 20% for some cases and it should not be ignored. Due to the prominent correction, it is possible to tune the Casimir force by such an effect.

Three complexes Cu(ppca)2(H2O)2(NO3)2 (1), Cu2(μ-OH)2(ppca)2(H2O)4}·(ClO4)2 (2) and Cu2(μ-CH3COO)4(ppca)2 (3) have been synthesized by the reaction of copper(II) salts with N-phenyl-4-pyridinecarboxamide (ppca) and characterized. For anions, in complex 1, NO3- coordinated with copper(II), in complex 2 perchlorate anion did not take part in coordination, the copper(II) cations were connected by μ-OH to form a dinuclear unit, and complex 3 had a dimeric copper(II) carboxylate paddle-wheel core. Noncovalent interactions linked these complexes to form supramolecular networks. Different coordinating modes of anions controlled modes of intermolecular interactions, which resulted in different final structures.

The crystal and molecular structures of cydta (trans-1, 2-cyclohexanediaminetetraacetic acid) have been determined by single-crystal X-ray structure analyses. The reasons that REIII-edta and REIII-cydta complexes select different coordinate structures were discussed and illustrated through the comparison of the molecular and crystal structures between edta and cydta, (NH4) [YIII (edta) (H2O)3]·5H2O and (NH4)[YIII (cydta) (H2O)2]·5H2O as well as (NH4) [GdIII (edta) (H2O)3)]·5H2O and (NH4) [GdIII (cydta) (H2O)2]·5H2O complexes.