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18 results on '"ZEIMER, MEIKE"'

5. Maculäre Teleangiektasien (MacTel) - Änderungen der Photorezeptorenschichtdicke im OCT in Assoziation mit Veränderungen der Konzentrationen an makulärem Pigment

Author

Zeimer, Meike, Spital, G., Heimes, B., Lommatzsch, A., and Pauleikhoff, D.

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Hintergrund: Sind Veränderungen in Konzentration und Verteilungsmuster des Makulären Pigments (MP) mit unterschiedlicher Dicke der Photorezeptorenschichten (PR) vergesellschaftet? Methoden: Die PRDicke wurde in 200 µm Schritten von 1600 µm temporal bis 1600 µm nasal [for full text, please go to the a.m. URL], 177. Versammlung des Vereins Rheinisch-Westfälischer Augenärzte

Published
2015

6. Maculäre Teleangiektasien (MacTel) - Hinweise auf zelldegenerative Prozesse im OCT unter Berücksichtigung der Verteilung und Konzentration des makulären Pigments

Author

Zeimer, Meike, Spital, G., Lommatzsch, A., and Pauleikhoff, D.

Subjects
ddc: 610, 610 Medical sciences, Medicine
Abstract

Hintergrund: Die Stadieneinteilung nach Ausmaß der Veränderungen im Verteilungsmuster des makulären Pigments (MP) bei Patienten mit makulären Teleangiaktasien Typ IIa n. Gass (MacTel) scheint den Schweregrad der Erkrankung widerzuspiegeln, zumindest legen verschiedene funktionelle[for full text, please go to the a.m. URL], 176. Versammlung des Vereins Rheinisch-Westfälischer Augenärzte

Published
2014
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16. MACULAR TELANGIECTASIA

Author

Zeimer, Meike B, primary, Krömer, Isabel, additional, Spital, Georg, additional, Lommatzsch, Albrecht, additional, and Pauleikhoff, Daniel, additional

Published
2010
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18. Macular telangiectasia: patterns of distribution of macular pigment and response to supplementation.

Author

Zeimer MB, Krömer I, Spital G, Lommatzsch A, and Pauleikhoff D

Subjects
Administration, Oral, Adult, Aged, Female, Fluorescein Angiography, Humans, Lutein metabolism, Macula Lutea pathology, Male, Middle Aged, Retinal Diseases classification, Retinal Diseases complications, Retinal Vessels pathology, Telangiectasis classification, Telangiectasis complications, Tomography, Optical Coherence, Visual Acuity, Visual Field Tests, Xanthophylls metabolism, Zeaxanthins, Dietary Supplements, Lutein administration & dosage, Macula Lutea metabolism, Retinal Diseases metabolism, Retinal Pigments metabolism, Telangiectasis metabolism, Xanthophylls administration & dosage
Abstract

Purpose: By analyzing the patterns of macular pigment (MP) in type 2 idiopathic telangiectasia eyes, different stages in the changes reflecting the extent of disease can be observed. The purpose of this study was to determine whether the amount and the pattern of MP can be influenced by supplementation., Method: Eleven patients with type 2 idiopathic telangiectasia received 12 mg lutein and 0.6 mg zeaxanthin (Ocuvite Lutein AMD) daily for 9 months. For a period of 12 months, MP concentration was determined every 3 months by autofluorescence (2 excitation wavelengths: 488 and 514 nm)., Results: When central accumulation of MP was similar to that in healthy subjects (with segment of reduced MP in the temporal fovea: MP Class I), supplementation enriched the MP at 0.5 degrees, 2 degrees, and 5 degrees to 6 degrees. In MP Class II (reduced concentration of MP centrally), accumulation could be detected at 2 degrees and 5 degrees to 6 degrees but not centrally. In MP Class III (oval-shaped effacement of MP centrally, surrounding oval-shaped ring of MP at 5 degrees-7 degrees eccentricity), supplementation promoted MP accumulation only at 5 degrees to 6 degrees., Conclusion: After oral supplementation with lutein/zeaxanthin, an increase in the MP was detected only in areas where the MP was present at baseline. Supplementation did not produce an increase in the area where the MP was absent. Degenerative processes causing an impairment in transport and storage of lutein and zeaxanthin may play a leading role in the pathogenesis of type 2 idiopathic telangiectasia.

Published
2010
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