352 results on '"Yusa, Kosuke"'
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2. Genome-wide screening identifies Polycomb repressive complex 1.3 as an essential regulator of human naïve pluripotent cell reprogramming
3. Canonical BAF complex regulates the oncogenic program in human T-cell acute lymphoblastic leukemia
4. RENGE infers gene regulatory networks using time-series single-cell RNA-seq data with CRISPR perturbations
5. B1 SINE-binding ZFP266 impedes mouse iPSC generation through suppression of chromatin opening mediated by reprogramming factors
6. Sphingomyelin synthase 1 supports two steps of rubella virus life cycle
7. Transposon delivery for CRISPR-based loss-of-function screen in mice identifies NF2 as a cooperating gene involved with the canonical WNT signaling molecular class of hepatocellular carcinoma
8. AKT-mTORC1 reactivation is the dominant resistance driver for PI3Kβ/AKT inhibitors in PTEN-null breast cancer and can be overcome by combining with Mcl-1 inhibitors
9. Pharmacologic characterization of TBP1901, a prodrug form of aglycone curcumin, and CRISPR-Cas9 screen for therapeutic targets of aglycone curcumin
10. The CADM1 tumor suppressor gene is a major candidate gene in MDS with deletion of the long arm of chromosome 11
11. Author Correction: Pooled extracellular receptor-ligand interaction screening using CRISPR activation
12. KAT7 is a genetic vulnerability of acute myeloid leukemias driven by MLL rearrangements
13. ARID1A influences HDAC1/BRD4 activity, intrinsic proliferative capacity and breast cancer treatment response
14. Minimal genome-wide human CRISPR-Cas9 library
15. Genome-wide CRISPR-Cas9 screening in mammalian cells
16. Genome-wide CRISPR Screens in T Helper Cells Reveal Pervasive Crosstalk between Activation and Differentiation
17. Genome‐wide loss‐of‐function genetic screen identifies INSIG2 as the vulnerability of hepatitis B virus‐integrated hepatoma cells
18. Genome-wide CRISPR-KO Screen Uncovers mTORC1-Mediated Gsk3 Regulation in Naive Pluripotency Maintenance and Dissolution
19. Prioritization of cancer therapeutic targets using CRISPR–Cas9 screens
20. Inference of gene regulatory networks using time-series single-cell RNA-seq data with CRISPR perturbations
21. Constitutively Active SMAD2/3 Are Broad-Scope Potentiators of Transcription-Factor-Mediated Cellular Reprogramming
22. Molecular synergy underlies the co-occurrence patterns and phenotype of NPM1-mutant acute myeloid leukemia
23. Low rates of mutation in clinical grade human pluripotent stem cells under different culture conditions
24. Agreement between two large pan-cancer CRISPR-Cas9 gene dependency data sets
25. Functional linkage of gene fusions to cancer cell fitness assessed by pharmacological and CRISPR-Cas9 screening
26. Structural rearrangements generate cell-specific, gene-independent CRISPR-Cas9 loss of fitness effects
27. RENGE infers gene regulatory networks using time-series single-cell RNA-seq data with CRISPR perturbations
28. Genome-scale CRISPR‒Cas9 screen identifies novel host factors as potential therapeutic targets for SARS-CoV-2 infection
29. Author Correction: ARID1A influences HDAC1/BRD4 activity, intrinsic proliferative capacity and breast cancer treatment response
30. ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks
31. SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4
32. Pooled extracellular receptor-ligand interaction screening using CRISPR activation
33. Unsupervised correction of gene-independent cell responses to CRISPR-Cas9 targeting
34. A Genetic Progression Model of BrafV600E-Induced Intestinal Tumorigenesis Reveals Targets for Therapeutic Intervention
35. Nuclear Wave1 Is Required for Reprogramming Transcription in Oocytes and for Normal Development
36. The critical role of histone H2A-deubiquitinase Mysm1 in hematopoiesis and lymphocyte differentiation
37. Peroxisomal Membrane Protein PMP34 Is Involved in the Human Papillomavirus Infection Pathway
38. Interhomolog recombination and loss of heterozygosity in wild-type and Bloom syndrome helicase (BLM)-deficient mammalian cells
39. A hyperactive piggyBac transposase for mammalian applications
40. PiggyBac Transposon Mutagenesis: A Tool for Cancer Gene Discovery in Mice
41. Pharmacologic characterization of TBP1901, a prodrug form of aglycone curcumin, and CRISPR-Cas9 screen for therapeutic targets of aglycone curcumin
42. Selective targeting of multiple myeloma cells with a monoclonal antibody recognizing the ubiquitous protein CD98 heavy chain
43. piggyBacTransposony
44. B1 SINE-binding ZFP266 impedes reprogramming through suppression of chromatin opening by pioneering factors
45. Seamless genome editing in human pluripotent stem cells using custom endonuclease–based gene targeting and the piggyBac transposon
46. piggyBac Transposon-Based Insertional Mutagenesis in Mouse Haploid Embryonic Stem Cells
47. Inhibition of Lysine Acetyltransferases p300/CBP Overcomes BTK Inhibitor Resistance in Mantle Cell Lymphoma Cells
48. CNOT4 Knockout Induces Proteasome Inhibitor Resistance in Multiple Myeloma Cells
49. Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells
50. Additional file 1 of Minimal genome-wide human CRISPR-Cas9 library
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