70 results on '"Yuntian Liu"'
Search Results
2. Hypertension Trends and Disparities Over 12 Years in a Large Health System: Leveraging the Electronic Health Records
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John E. Brush, Yuan Lu, Yuntian Liu, Jordan R. Asher, Shu‐Xia Li, Mitsuaki Sawano, Patrick Young, Wade L. Schulz, Mark Anderson, John S. Burrows, and Harlan M. Krumholz
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health systems ,hypertension prevalence ,racial disparities ,real‐world data ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Background The digital transformation of medical data enables health systems to leverage real‐world data from electronic health records to gain actionable insights for improving hypertension care. Methods and Results We performed a serial cross‐sectional analysis of outpatients of a large regional health system from 2010 to 2021. Hypertension was defined by systolic blood pressure ≥140 mm Hg, diastolic blood pressure ≥90 mm Hg, or recorded treatment with antihypertension medications. We evaluated 4 methods of using blood pressure measurements in the electronic health record to define hypertension. The primary outcomes were age‐adjusted prevalence rates and age‐adjusted control rates. Hypertension prevalence varied depending on the definition used, ranging from 36.5% to 50.9% initially and increasing over time by ≈5%, regardless of the definition used. Control rates ranged from 61.2% to 71.3% initially, increased during 2018 to 2019, and decreased during 2020 to 2021. The proportion of patients with a hypertension diagnosis ranged from 45.5% to 60.2% initially and improved during the study period. Non‐Hispanic Black patients represented 25% of our regional population and consistently had higher prevalence rates, higher mean systolic and diastolic blood pressure, and lower control rates compared with other racial and ethnic groups. Conclusions In a large regional health system, we leveraged the electronic health record to provide real‐world insights. The findings largely reflected national trends but showed distinctive regional demographics and findings, with prevalence increasing, one‐quarter of the patients not controlled, and marked disparities. This approach could be emulated by regional health systems seeking to improve hypertension care.
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- 2024
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3. Enumeration and Representation Theory of Spin Space Groups
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Xiaobing Chen, Jun Ren, Yanzhou Zhu, Yutong Yu, Ao Zhang, Pengfei Liu, Jiayu Li, Yuntian Liu, Caiheng Li, and Qihang Liu
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Physics ,QC1-999 - Abstract
Fundamental physical properties, such as phase transitions, electronic structures, and spin excitations, in all magnetic ordered materials, were ultimately believed to rely on the symmetry theory of magnetic space groups. Recently, it has come to light that a more comprehensive group, known as the spin space group (SSG), which combines separate spin and spatial operations, is necessary to fully characterize the geometry and underlying properties of magnetic ordered materials. However, the basic theory of SSG has seldom been developed. In this work, we present a systematic study of the enumeration and the representation theory of the SSG. Starting from the 230 crystallographic space groups and finite translation groups with a maximum order of eight, we establish an extensive collection of over 100 000 SSGs under a four-index nomenclature as well as international notation. We then identify inequivalent SSGs specifically applicable to collinear, coplanar, and noncoplanar magnetic configurations. To facilitate the identification of the SSG, we develop an online program that can determine the SSG symmetries of any magnetic ordered crystal. Moreover, we derive the irreducible corepresentations of the little group in momentum space within the SSG framework. Finally, we illustrate the SSG symmetries and physical effects beyond the framework of magnetic space groups through several representative material examples, including a candidate altermagnet RuO_{2}, spiral spin polarization in the coplanar antiferromagnet CeAuAl_{3}, and geometric Hall effect in the noncoplanar antiferromagnet CoNb_{3}S_{6}. Our work advances the field of group theory in describing magnetic ordered materials, opening up avenues for deeper comprehension and further exploration of emergent phenomena in magnetic materials.
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- 2024
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4. Detection of Surface Rocks and Small Craters in Permanently Shadowed Regions of the Lunar South Pole Based on YOLOv7 and Markov Random Field Algorithms in SAR Images
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Tong Xia, Xuancheng Ren, Yuntian Liu, Niutao Liu, Feng Xu, and Ya-Qiu Jin
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crater detection ,rocks ,lunar south pole ,PSR ,SAR ,Science - Abstract
Excluding rough areas with surface rocks and craters is critical for the safety of landing missions, such as China’s Chang’e-7 mission, in the permanently shadowed region (PSR) of the lunar south pole. Binned digital elevation model (DEM) data can describe the undulating surface, but the DEM data can hardly detect surface rocks because of median-averaging. High-resolution images from a synthetic aperture radar (SAR) can be used to map discrete rocks and small craters according to their strong backscattering. This study utilizes the You Only Look Once version 7 (YOLOv7) tool to detect varying-sized craters in SAR images. It also employs the Markov random field (MRF) algorithm to identify surface rocks, which are usually difficult to detect in DEM data. The results are validated by optical images and DEM data in non-PSR. With the assistance of the DEM data, regions with slopes larger than 10° are excluded. YOLOv7 and MRF are applied to detect craters and rocky surfaces and exclude regions with steep slopes in the PSRs of craters Shoemaker, Slater, and Shackleton, respectively. This study proves SAR images are feasible in the selection of landing sites in the PSRs for future missions.
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- 2024
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5. Spectroscopic signature of obstructed surface states in SrIn2P2
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Xiang-Rui Liu, Hanbin Deng, Yuntian Liu, Zhouyi Yin, Congrun Chen, Yu-Peng Zhu, Yichen Yang, Zhicheng Jiang, Zhengtai Liu, Mao Ye, Dawei Shen, Jia-Xin Yin, Kedong Wang, Qihang Liu, Yue Zhao, and Chang Liu
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Science - Abstract
Abstract The century-long development of surface sciences has witnessed the discoveries of a variety of quantum states. In the recently proposed “obstructed atomic insulators”, symmetric charges are pinned at virtual sites where no real atoms reside. The cleavage through these sites could lead to a set of obstructed surface states with partial electronic occupation. Here, utilizing scanning tunneling microscopy, angle-resolved photoemission spectroscopy and first-principles calculations, we observe spectroscopic signature of obstructed surface states in SrIn2P2. We find that a pair of surface states that are originated from the pristine obstructed surface states split in energy by a unique surface reconstruction. The upper branch is marked with a striking differential conductance peak followed by negative differential conductance, signaling its localized nature, while the lower branch is found to be highly dispersive. This pair of surface states is in consistency with our calculational results. Our finding not only demonstrates a surface quantum state induced by a new type of bulk-boundary correspondence, but also provides a platform for exploring efficient catalysts and related surface engineering.
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- 2023
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6. Contextualizing sociodemographic differences in Tibetan attitudes toward large carnivores
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Yufang Gao, Yiqing Wang, Andy T. L. Lee, Yuntian Liu, Yu Luo, Kaggie Orrick, Justine Shanti Alexander, Ju Tashi Sangpo, and Susan G. Clark
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ABC model ,brown bear ,gray wolf ,snow leopard ,Tibet ,Ecology ,QH540-549.5 ,General. Including nature conservation, geographical distribution ,QH1-199.5 - Abstract
Abstract Fostering human–wildlife coexistence necessitates a thorough and nuanced grasp of local attitudes toward wildlife. Attitudes can vary substantially based on the sociodemographic backgrounds of individuals within a society. This study examines Tibetan attitudes toward large carnivores, emphasizing the importance of contextualization in discerning the effects of sociodemographic factors on attitudes. We began by analyzing existing research on Tibetan attitudes toward wildlife in China, identifying previously studied sociodemographic variables. We then executed an online survey to evaluate the affective, behavioral, cognitive, and overall attitudes of ethnic Tibetans in China toward snow leopards (Panthera uncia), gray wolves (Canis lupus), and brown bears (Ursus arctos). Our findings show that while factors such as gender, age, religious identity, and level of education shape these attitudes, their influence differs depending on the specific attitude component and the target animal under examination. Therefore, making broad generalizations about sociodemographic differences in attitudes can be misleading. It is imperative for attitude research to clearly define the attitude component (what type of attitude), object (attitude toward what), and circumstance (attitude in which situation) being studied. Conducting ethnographic fieldwork in collaboration with local cultural experts can deepen our understanding of local perspectives and the ways sociodemographic factors influence attitudes. Such insights are pivotal for developing conservation strategies attuned to local sociocultural contexts.
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- 2023
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7. Multinational patterns of second line antihyperglycaemic drug initiation across cardiovascular risk groups: federated pharmacoepidemiological evaluation in LEGEND-T2DM
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Rohan Khera, Yuan Lu, Michael E Matheny, Kenneth KC Man, Paul Nagy, Nigam Shah, Martijn J Schuemie, Scott L DuVall, Seng Chan You, Jose D Posada, George Hripcsak, Marc A Suchard, Patrick B Ryan, Anna Ostropolets, Evan Minty, Clair Blacketer, Arya Aminorroaya, Thomas Falconer, Nestoras Mathioudakis, Jin J Zhou, Can Yin, Kelly Li, Lovedeep Singh Dhingra, Faaizah Arshad, Mary G Bowring, Fan Bu, David A Dorr, Tina E French, Elizabeth E Hanchrow, Scott Horban, Wallis CY Lau, Yuntian Liu, Michael F McLemore, Akihiko Nishimura, Sarah Seager, Eric YF Wan, and Jianxiao Yang
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Medicine - Abstract
Objective To assess the uptake of second line antihyperglycaemic drugs among patients with type 2 diabetes mellitus who are receiving metformin.Design Federated pharmacoepidemiological evaluation in LEGEND-T2DM.Setting 10 US and seven non-US electronic health record and administrative claims databases in the Observational Health Data Sciences and Informatics network in eight countries from 2011 to the end of 2021.Participants 4.8 million patients (≥18 years) across US and non-US based databases with type 2 diabetes mellitus who had received metformin monotherapy and had initiated second line treatments.Exposure The exposure used to evaluate each database was calendar year trends, with the years in the study that were specific to each cohort.Main outcomes measures The outcome was the incidence of second line antihyperglycaemic drug use (ie, glucagon-like peptide-1 receptor agonists, sodium-glucose cotransporter-2 inhibitors, dipeptidyl peptidase-4 inhibitors, and sulfonylureas) among individuals who were already receiving treatment with metformin. The relative drug class level uptake across cardiovascular risk groups was also evaluated.Results 4.6 million patients were identified in US databases, 61 382 from Spain, 32 442 from Germany, 25 173 from the UK, 13 270 from France, 5580 from Scotland, 4614 from Hong Kong, and 2322 from Australia. During 2011-21, the combined proportional initiation of the cardioprotective antihyperglycaemic drugs (glucagon-like peptide-1 receptor agonists and sodium-glucose cotransporter-2 inhibitors) increased across all data sources, with the combined initiation of these drugs as second line drugs in 2021 ranging from 35.2% to 68.2% in the US databases, 15.4% in France, 34.7% in Spain, 50.1% in Germany, and 54.8% in Scotland. From 2016 to 2021, in some US and non-US databases, uptake of glucagon-like peptide-1 receptor agonists and sodium-glucose cotransporter-2 inhibitors increased more significantly among populations with no cardiovascular disease compared with patients with established cardiovascular disease. No data source provided evidence of a greater increase in the uptake of these two drug classes in populations with cardiovascular disease compared with no cardiovascular disease.Conclusions Despite the increase in overall uptake of cardioprotective antihyperglycaemic drugs as second line treatments for type 2 diabetes mellitus, their uptake was lower in patients with cardiovascular disease than in people with no cardiovascular disease over the past decade. A strategy is needed to ensure that medication use is concordant with guideline recommendations to improve outcomes of patients with type 2 diabetes mellitus.
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- 2023
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8. Racial and Ethnic Disparities in Financial Barriers Among Overweight and Obese Adults Eligible for Semaglutide in the United States
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Yuan Lu, Yuntian Liu, and Harlan M. Krumholz
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antiobesity agents ,disparities ,health equity ,obesity ,race and ethnicity ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Background Semaglutide holds the promise for weight loss and risk reduction. Less is known about racial and ethnic disparities in financial barriers among the semaglutide‐eligible population. Methods and Results We conducted a cross‐sectional analysis of adults aged 18 years or older using data from the National Health and Nutrition Examination Survey 2015 to 2020. We analyzed adults eligible for semaglutide based on Food and Drug Administration labeling and assessed financial barriers and social determinants of health among the eligible population overall and by race and ethnicity. A total of 13 711 adults were included in the final analysis. In 2015 to 2020, 51.1% (48.3%–53.2%) of US adults (≈112.5 million) met the Food and Drug Administration eligibility criteria for semaglutide. The percentage of adults eligible for semaglutide was highest among Black adults (56.6% [54.2%–59.1%]), followed by Hispanic adults (55.0% [52.8%–57.3%]). Among adults eligible for semaglutide, 11.9% (10.1%–13.6%) were uninsured, 13.3% (12.1%–14.5%) lacked a usual source of care, 33.6% (30.2%–36.9%) had low family income, and 38.9% (36.5%–41.3%) lacked higher education. Compared with White individuals, significantly larger proportions of Black and Hispanic individuals were uninsured, lacked a usual source of care, had low family income, or lacked higher education (P
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- 2022
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9. A van der Waals antiferromagnetic topological insulator with weak interlayer magnetic coupling
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Chaowei Hu, Kyle N. Gordon, Pengfei Liu, Jinyu Liu, Xiaoqing Zhou, Peipei Hao, Dushyant Narayan, Eve Emmanouilidou, Hongyi Sun, Yuntian Liu, Harlan Brawer, Arthur P. Ramirez, Lei Ding, Huibo Cao, Qihang Liu, Dan Dessau, and Ni Ni
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Science - Abstract
Emergent quantum phenomena such as quantized anomalous Hall effect may be realized in magnetic topological materials. Here, Hu et al. discovered an intrinsic natural heterostructural Z2 antiferromagnetic topological insulator MnBi4Te7 with low out-of-plane saturation fields.
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- 2020
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10. Distinct Topological Surface States on the Two Terminations of MnBi_{4}Te_{7}
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Xuefeng Wu, Jiayu Li, Xiao-Ming Ma, Yu Zhang, Yuntian Liu, Chun-Sheng Zhou, Jifeng Shao, Qiaoming Wang, Yu-Jie Hao, Yue Feng, Eike F. Schwier, Shiv Kumar, Hongyi Sun, Pengfei Liu, Kenya Shimada, Koji Miyamoto, Taichi Okuda, Kedong Wang, Maohai Xie, Chaoyu Chen, Qihang Liu, Chang Liu, and Yue Zhao
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Physics ,QC1-999 - Abstract
The recently discovered intrinsic magnetic topological insulator MnBi_{2}Te_{4} has been met with unusual success in hosting emergent phenomena such as the quantum anomalous Hall effect and the axion insulator states. However, the surface-bulk correspondence of the Mn-Bi-Te family, composed by the superlatticelike MnBi_{2}Te_{4}/(Bi_{2}Te_{3})_{n} (n=0,1,2,3…) layered structure, remains intriguing but elusive. Here, by using scanning tunneling microscopy and angle-resolved photoemission spectroscopy techniques, we unambiguously assign the two distinct surface states of MnBi_{4}Te_{7} (n=1) to the quintuple-layer (QL) Bi_{2}Te_{3} termination and the septuple-layer (SL) MnBi_{2}Te_{4} termination, respectively. A comparison of the experimental observations with theoretical calculations reveals diverging topological behaviors, especially the hybridization effect between the QL and SL, on the two terminations. We identify a gap on the QL termination, originating from the hybridization between the topological surface states of the QL and the bands of the SL beneath, and a gapless Dirac-cone band structure on the SL termination with time-reversal symmetry. The quasiparticle interference patterns further confirm the topological nature of the surface states for both terminations, continuing far above the Fermi energy. The QL termination carries a spin-helical Dirac state with hexagonal warping, while at the SL termination, a strongly canted helical state from the surface lies between a pair of Rashba-like splitting bands from its neighboring layer. Our work elucidates an unprecedented hybridization effect between the building blocks of the topological surface states and also reveals the termination-dependent time-reversal symmetry breaking in a magnetic topological insulator.
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- 2020
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11. A Novel Battery State of Charge Estimation Method Based on a Super-Twisting Sliding Mode Observer
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Yigeng Huangfu, Jiani Xu, Dongdong Zhao, Yuntian Liu, and Fei Gao
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super-twisting algorithm ,sliding mode observer ,second-order RC equivalent circuit model ,Li-ion battery ,state of charge ,Technology - Abstract
A novel method for Li-ion battery state of charge (SOC) estimation based on a super-twisting sliding mode observer (STSMO) is proposed in this paper. To design the STSMO, the state equation of a second-order RC equivalent circuit model (SRCECM) is derived to represent the dynamic behaviors of the Li-ion battery, and the model parameters are determined by the pulse current discharge approach. The convergence of the STSMO is proven by Lyapunov stability theory. The experiments under three different discharge profiles are conducted on the Li-ion battery. Through comparisons with a conventional sliding mode observer (CSMO) and adaptive extended Kalman filter (AEKF), the superiority of the proposed observer for SOC estimation is validated.
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- 2018
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12. Large Scale Triboelectric Nanogenerator and Self-Powered Flexible Sensor for Human Sleep Monitoring
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Xiaoheng Ding, Hailin Cao, Xinghong Zhang, Mingyu Li, and Yuntian Liu
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self-powered sensor ,triboelectric ,flexible sensor ,sleeping monitoring ,Chemical technology ,TP1-1185 - Abstract
The triboelectric nanogenerator (TENG) and its application as a sensor is a popular research subject. There is demand for self-powered, flexible sensors with high sensitivity and high power-output for the next generation of consumer electronics. In this study, a 300 mm × 300 mm carbon nanotube (CNT)-doped porous PDMS film was successfully fabricated wherein the CNT influenced the micropore structure. A self-powered TENG tactile sensor was established according to triboelectric theory. The CNT-doped porous TENG showed a voltage output seven times higher than undoped porous TENG and 16 times higher than TENG with pure PDMS, respectively. The TENG successfully acquired human motion signals, breath signals, and heartbeat signals during a sleep monitoring experiment. The results presented here may provide an effective approach for fabricating large-scale and low-cost flexible TENG sensors.
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- 2018
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13. Nonexercise machine learning models for maximal oxygen uptake prediction in national population surveys.
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Yuntian Liu, Jeph Herrin, Chenxi Huang, Rohan Khera, Lovedeep Singh Dhingra, Weilai Dong, Bobak J. Mortazavi, Harlan M. Krumholz, and Yuan Lu
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- 2023
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14. Intelligent Dental Triage System oriented on Dental Symptom Knowledge Base.
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Muyao Tang, Luwang Zhou, Yongheng Zhao, and Yuntian Liu
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- 2022
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15. Recurrent LSTM-based UAV Trajectory Prediction with ADS-B Information.
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Yifan Zhang, Ziye Jia, Chao Dong 0001, Yuntian Liu, Lei Zhang 0038, and Qihui Wu
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- 2022
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16. Application of Data Integration in Dataspace in Multi-value Chain Collaboration of Electric Power Manufacturing Industry.
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Yuntian Liu, Dongxiao Niu, Shiping Geng, Jingqi Sun, and Huanfen Zhang
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- 2022
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17. Research on Data Acquisition and Processing Under the Coordination of Multiple Value Chains in the Manufacturing Industry - Taking the Electric Vehicle Manufacturing Industry as an Example.
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Shiping Geng, Yuntian Liu, Dongxiao Niu, and Xiaopeng Guo
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- 2021
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18. An Improved State Machine Strategy for Fuel-Cell-Based Hybrid Electric Vehicles.
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Haiyan Li, Dongdong Zhao, Yuxiang Zhang, Zehua Liang, Hanbin Dang, and Yuntian Liu
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- 2020
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19. A Novel Diagnosis Method of Proton Exchange Membrane Fuel Cells Based on the PCA and XGBoost Algorithm.
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Hanbin Dang, Rui Ma, Dongdong Zhao, Renyou Xie, Haiyan Li, and Yuntian Liu
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- 2020
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20. Hypertension Trends and Disparities Over 12 Years in a Large Health System: Leveraging the Electronic Health Records.
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Brush Jr, John E., Yuan Lu, Yuntian Liu, Asher, Jordan R., Shu-Xia Li, Mitsuaki Sawano, Young, Patrick, Schulz, Wade L., Anderson, Mark, Burrows, John S., and Krumholz, Harlan M.
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- 2024
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21. State of Charge Estimation of Lithium-ion Batteries Electrochemical Model with Extended Kalman Filter.
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Yuntian Liu, Yigeng Huangfu, Rui Ma, Liangcai Xu, Dongdong Zhao, and Jiang Wei
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- 2019
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22. Small Signal Analysis and Control Design of Snubberless Naturally Clamped ZCS/ZVS Current-Fed Half-Bridge DC/DC Converter for EV.
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Minchi Xie, Yigeng Huangfu, Qingchao Zhang, Qian Li, Dongdong Zhao, and Yuntian Liu
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- 2018
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23. State-of-Charge Co-estimation of Li-ion Battery based on on-line Adaptive Extended Kalman Filter Carrier Tracking Algorithm.
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Yuntian Liu, Yigeng Huangfu, Jiani Xu, Dongdong Zhao, Liangcai Xu, and Minchi Xie
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- 2018
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24. Laser Image Enhancement Algorithm Based on Improved EnlightenGAN
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Youchen Fan, Yitong Wang, Kai Feng, Yuntian Liu, Yawen Jiang, Jiaxuan Xie, Yufei Niu, and Hongyan Wang
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laser image enhancement ,EnlightenGAN ,dual discriminator ,self-attention mechanism ,Computer Networks and Communications ,Hardware and Architecture ,Control and Systems Engineering ,Signal Processing ,Electrical and Electronic Engineering - Abstract
In distance-selected imaging, the contrast of laser images is reduced due to long imaging distances, insufficient laser power, and atmospheric turbulence. An enhancement algorithm based on the EnlightenGAN network is proposed to improve the contrast of laser images. Firstly, the laser images are acquired using a distance selection pass system to establish the laser image dataset and expand the dataset, and the traditional algorithm is used to enhance the images and establish the mapping relationship between low-quality images and high-quality images. The global discriminator based on PatchGAN with the improved VGG model is used to regularize the self-feature retention loss and construct the depth link between the global discriminator and the local discriminator to improve the generalization ability of the model; adjust the attention map to the second layer before the CLB convolution module and also add the residual structure in the second layer CLB to improve the robustness of the model; adopt the idea of gray-scale layering with a low drop and high rise to improve the self regularization mechanism to achieve the enhancement of the key region; finally, use the improved EnlightenGAN to fit the relationship between a low-quality image and high-quality image. Finally, EnlightenGAN is used to fit the relationship between low-quality images and high-quality images, extract laser image features, and enhance low-quality images. The experimental results show that the improved algorithm improves PSNR by 12.3% and 0.7% on average, SSIM by 57% and 10.3% on average, and NIQE by 21% and 13% on average compared to other algorithms and the original EnlightenGAN algorithm, respectively. The algorithm improves the signal-to-noise ratio and contrast of laser images with richer image details. It provides a new idea for pre-processing laser images.
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- 2023
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25. Tracking Chinese newspaper coverage of elephant ivory through topic modeling
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Yufang Gao, Yuntian Liu, Yu Luo, Duan Biggs, Weiyang Zhao, and Susan G. Clark
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Ecology ,Ecology, Evolution, Behavior and Systematics ,Nature and Landscape Conservation - Published
- 2023
26. Van der Waals Engineering of Ultrafast Carrier Dynamics in Magnetic Heterostructures
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Paulina Ewa Majchrzak, Yuntian Liu, Klara Volckaert, Deepnarayan Biswas, Chakradhar Sahoo, Denny Puntel, Wibke Bronsch, Manuel Tuniz, Federico Cilento, Xing-Chen Pan, Qihang Liu, Yong P. Chen, Søren Ulstrup, Majchrzak, Paulina Ewa, Liu, Yuntian, Volckaert, Klara, Biswas, Deepnarayan, Sahoo, Chakradhar, Puntel, Denny, Bronsch, Wibke, Tuniz, Manuel, Cilento, Federico, Pan, Xing-Chen, Liu, Qihang, Chen, Yong P, and Ulstrup, Søren
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MnBi2Te4 ,density functional theory ,magnetic topological insulators ,time- and angle-resolved photoemission spectroscopy ,ultrafast carrier dynamics ,van der Waals heterostructures ,Condensed Matter - Materials Science ,Mechanical Engineering ,Materials Science (cond-mat.mtrl-sci) ,FOS: Physical sciences ,MnBiTe ,Bioengineering ,General Chemistry ,Condensed Matter Physics ,ultrafast carrier dynamic ,magnetic topological insulator ,General Materials Science - Abstract
Heterostructures composed of the intrinsic magnetic topological insulator MnBi$_2$Te$_4$ and its non-magnetic counterpart Bi$_2$Te$_3$ host distinct surface band structures depending on the stacking order and exposed termination, allowing fine control of their magnetic, electronic and optical properties. Here, we probe the ultrafast dynamical response of MnBi$_2$Te$_4$ and MnBi$_4$Te$_7$ following near-infrared optical excitation using time- and angle-resolved photoemission spectroscopy. We gain access to the out-of-equilibrium surface electronic structure of both MnBi$_2$Te$_4$ and Bi$_2$Te$_3$ surface terminations of MnBi$_4$Te$_7$, revealing an instantaneous occupation of states that are resonant with the optical excitation in the Bi$_2$Te$_3$ layer followed by carrier extraction into the adjacent MnBi$_2$Te$_4$ layers with a laser fluence-tunable delay of up to 350 fs. The ensuing thermal relaxation processes are driven by in-plane phonon scattering with significantly slower relaxation times in the magnetic MnBi$_2$Te$_4$ septuple layers. The competition of interlayer charge transfer and intralayer phonon scattering establishes MnBi$_2$Te$_4$-based compounds as a platform for controlling ultrafast charge transfer processes in combination with magnetism and topology in van der Waals heterostructures., 17 pages, 4 figures
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- 2023
27. Eligibility for Cardiovascular Risk Reduction Therapy in the United States Based on SELECT Trial Criteria: Insights From the National Health and Nutrition Examination Survey.
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Yuan Lu, Yuntian Liu, Jastreboff, Ania M., Khera, Rohan, Ndumele, Chima D., Rodriguez, Fatima, Watson, Karol E., and Krumholz, Harlan M.
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- 2024
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28. Multinational Patterns of Second-line Anti-hyperglycemic Drug Initiation Across Cardiovascular Risk Groups: A Federated Pharmacoepidemiologic Evaluation in LEGEND-T2DM
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Rohan Khera, Lovedeep Singh Dhingra, Arya Aminorroaya, Kelly Li, Jin J Zhou, Faaizah Arshad, Clair Blacketer, Mary G Bowring, Fan Bu, Michael Cook, David A Dorr, Talita Duarte-Salles, Scott L DuVall, Thomas Falconer, Tina E French, Elizabeth E Hanchrow, Scott Horban, Wallis CY Lau, Jing Li, Yuntian Liu, Yuan Lu, Kenneth KC Man, Michael E Matheny, Nestoras Mathioudakis, Michael F McLemore, Evan Minty, Daniel R Morales, Paul Nagy, Akihiko Nishimura, Anna Ostropolets, Andrea Pistillo, Jose D Posada, Nicole Pratt, Carlen Reyes, Joseph Ross, Sarah L Seager, Nigam H Shah, Katherine R Simon, Eric YF Wan, Jianxiao Yang, Can Yin, Seng Chan You, Martijn J Schuemie, Patrick B Ryan, George Hripcsak, Harlan M Krumholz, and Marc A Suchard
- Abstract
ObjectivesTo assess the uptake of second-line antihyperglycemic agents among patients with type-2 diabetes mellitus (T2DM) receiving metformin.DesignSerial cross-sectional study (2011-2021).SettingTen US and seven non-US electronic health record and administrative claims databases in the Observational Health Data Sciences and Informatics network.Participants4.8 million patients with T2DM receiving metformin.Main Outcomes MeasuresCalendar-year trends in the proportional initiation of second-line antihyperglycemic agents, glucagon-like peptide-1 receptor agonists (GLP-1 RAs), sodium-glucose cotransporter 2 inhibitors (SGLT2is), dipeptidyl peptidase-4 inhibitors, and sulfonylureas, for each database. We also evaluated the relative drug class-level uptake across cardiovascular risk groups.ResultsWe identified 4.6 million patients with T2DM in US databases, 61,382 from Spain, 32,442 from Germany, 25,173 from the UK, 13,270 from France, 5,580 from Scotland, 4,614 from Hong Kong, and 2,322 from Australia. During 2011-2021, the combined proportional initiation of cardioprotective antihyperglycemic agents, GLP-1 RAs and SGLT2is, increased across all data sources, with the combined initiation of these drugs as second-line agents in 2021 ranging from 35.2% to 68.2% in the US databases, 15.4% in France, 34.7% in Spain, 50.1% in Germany, and 54.8% in Scotland. From 2016 to 2021, in some US and non-US databases, uptake of GLP-1 RAs and SGLT2is increased more significantly among populations without cardiovascular disease compared to those with established cardiovascular disease, without any data source providing evidence of a greater increase in their uptake in the populations with cardiovascular disease.ConclusionsDespite the increase in overall uptake of cardioprotective antihyperglycemic agents as second-line treatment for T2DM, their uptake was lower in patients with cardiovascular disease over the last decade. A strategy to ensure medication use concordant with guideline recommendations is essential to improve outcomes of patients with T2DM.
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- 2022
29. A Droop-based Energy Management Strategy for Electric Aircraft Hybrid Power System
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Hui Li, Yuntian Liu, Aiben Wang, Shengzhao Pang, and Yigeng Huangfu
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- 2022
30. Excess Mortality and Years of Potential Life Lost Among Black People in the US from 1999 to 2020
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César Caraballo, Daisy S. Massey, Chima D. Ndumele, Trent Haywood, Shayaan Kaleem, Terris King, Yuntian Liu, Yuan Lu, Marcella Nunez-Smith, Herman A. Taylor, Karol E. Watson, Jeph Herrin, Clyde W. Yancy, Jeremy S. Faust, and Harlan M. Krumholz
- Abstract
ImportanceAmid efforts in the United States to promote health equity, there is a need to assess progress in reducing excess deaths and years of potential life lost (YPLL) among Black people compared with White people.ObjectiveTo evaluate trends in excess mortality and YPLL among Black people compared with White people.DesignSerial cross-sectional.SettingNational data from the Centers for Disease Control and Prevention, 1999-2020ParticipantsNon-Hispanic White and non-Hispanic Black peopleExposuresRace as documented in the death certificates.Main outcomes and measuresExcess age-adjusted all-cause and disease-specific mortality rate (per 100,000 individuals) and YPLL among Black people compared with White people.ResultsFrom 1999 to 2020, the total number of excess deaths was 658,356 and 1,154,108 among Black females and males, representing 34,938,070 and 47,005,048 excess YPLL among Black females and males. The excess deaths and YPLL were largest among infants and non-elderly adults. Heart disease had the most excess deaths. From 1999, the age-adjusted excess mortality rate declined at an annual average of -9.0 (95% CI: -10.0, -8.0; PConclusions and relevanceOver a recent 22-year period, Black people in the US lost more than 80 million years of life when compared with White people. After a period of progress, improvements stalled, and most gains were eliminated in 2020.KEY POINTSQuestionHow many excess deaths and years of potential life lost (YPLL) for Black people, compared with White people, occurred in the United States from 1999 through 2020?FindingsBased on Centers for Disease Control and Prevention data, excess deaths and YPLL persisted throughout the period, with initial progress followed by little improvement, and then worsening in 2020 to about 1999 levels. Black people had 1.8 million excess deaths and over 80 million YPLL over the study period.MeaningAfter initial progress, excess mortality and YPLL among Black people stagnated and then worsened, indicating a need for new approaches.
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- 2022
31. Excess Mortality and Years of Potential Life Lost Among the Black Population in the US, 1999-2020
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César Caraballo, Daisy S. Massey, Chima D. Ndumele, Trent Haywood, Shayaan Kaleem, Terris King, Yuntian Liu, Yuan Lu, Marcella Nunez-Smith, Herman A. Taylor, Karol E. Watson, Jeph Herrin, Clyde W. Yancy, Jeremy Samuel Faust, and Harlan M. Krumholz
- Subjects
General Medicine - Abstract
ImportanceAmid efforts in the US to promote health equity, there is a need to assess recent progress in reducing excess deaths and years of potential life lost among the Black population compared with the White population.ObjectiveTo evaluate trends in excess mortality and years of potential life lost among the Black population compared with the White population.Design, setting, and participantsSerial cross-sectional study using US national data from the Centers for Disease Control and Prevention from 1999 through 2020. We included data from non-Hispanic White and non-Hispanic Black populations across all age groups.ExposuresRace as documented in the death certificates.Main outcomes and measuresExcess age-adjusted all-cause mortality, cause-specific mortality, age-specific mortality, and years of potential life lost rates (per 100 000 individuals) among the Black population compared with the White population.ResultsFrom 1999 to 2011, the age-adjusted excess mortality rate declined from 404 to 211 excess deaths per 100 000 individuals among Black males (P for trend P for trend = .98) and increased in 2020 to 395—rates not seen since 2000. Among Black females, the rate declined from 224 excess deaths per 100 000 individuals in 1999 to 87 in 2015 (P for trend P for trend = .71) and in 2020 rates increased to 192—levels not seen since 2005. The trends in rates of excess years of potential life lost followed a similar pattern. From 1999 to 2020, the disproportionately higher mortality rates in Black males and females resulted in 997 623 and 628 464 excess deaths, respectively, representing a loss of more than 80 million years of life. Heart disease had the highest excess mortality rates, and the excess years of potential life lost rates were largest among infants and middle-aged adults.Conclusions and relevanceOver a recent 22-year period, the Black population in the US experienced more than 1.63 million excess deaths and more than 80 million excess years of life lost when compared with the White population. After a period of progress in reducing disparities, improvements stalled, and differences between the Black population and the White population worsened in 2020.
- Published
- 2023
32. An Energy Management Strategy Based on Equivalent Consumption Minimum for Hybrid-Electric Aircraft with Battery Cooling System
- Author
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Tianying Yu, Yigeng Huangfu, Hao Bai, Yuntian Liu, Wenzhuo Shi, and Zelong Zhang
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- 2022
33. A Nonlinear Observer SOC Estimation Method Based on Electrochemical Model for Lithium-Ion Battery
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Dongdong Zhao, Yigeng Huangfu, Liangcai Xu, Shengzhao Pang, Yuntian Liu, Rui Ma, Fei Gao, and Jiang Wei
- Subjects
Lyapunov stability ,Battery (electricity) ,Observational error ,Computer science ,020209 energy ,020208 electrical & electronic engineering ,Environmental pollution ,02 engineering and technology ,Industrial and Manufacturing Engineering ,Lithium-ion battery ,Extended Kalman filter ,State of charge ,Rate of convergence ,Control and Systems Engineering ,Control theory ,0202 electrical engineering, electronic engineering, information engineering ,Electrical and Electronic Engineering - Abstract
As the global environmental pollution and energy crisis become more serious, lithium-ion batteries (LIB) received an increasing research interest due to their low self-discharge rates, long cycle life, and high power density for the transportation applications. Battery management system (BMS) plays an essential part for the LIB system as it can guarantee an efficient and stable operation through LIB state of charge (SOC) estimation. In this article, a nonlinear observer with terminal voltage feedback injection (VFNO) is designed based on the electrochemical single particle (SP) model to monitor the SOC of LIB. The convergence of the SP-VFNO system in consideration of measurement error is proved in terms of Lyapunov stability theory. The current, the terminal voltage, and the SOC reference value are measured in the battery testing system. Besides, the extended Kalman filter (EKF) based on both the SP model and the second-order resistor-capacitor (SORC) model to estimate SOC is adopted for comparison. The experimental results indicate that the proposed SP-VFNO method has superiority with a faster convergence rate and a higher estimation precision, which can help the accurate SOC estimation for BMS in practical application.
- Published
- 2021
34. Medication Guideline Adherence Among Patients with Markedly Elevated Blood Pressure in A Real-World Setting
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Yuan Lu, Chenxi Huang, Yuntian Liu, César Caraballo, Shiwani Mahajan, Daisy Massey, Erica S. Spatz, Oyere Onuma, Joseph S. Ross, Wade L. Schulz, and Harlan M. Krumholz
- Abstract
ObjectiveTo evaluate medication guideline adherence among ambulatory patients with markedly elevated blood pressure (BP), overall and by patient characteristics.DesignPopulation-based, retrospective cohort study.SettingYale New Haven Health System.ParticipantsAdult patients aged 18-85 years with markedly elevated BP (defined as two consecutive outpatient visits with systolic BP ≥160 mmHg or diastolic BP ≥100 mmHg) between October 1st, 2015 and December 31st, 2018.Main outcome measuresWe assessed the number and class of antihypertensive drugs (previously taken and newly prescribed) prior to 90 days of the second visit with BP ≥160/100 mmHg. Among patients treated with two-drug class regimens, we assessed the proportion of patients on guideline-recommended two drug classes, overall and stratified by documentation of prior myocardial infarction (MI), diabetes, chronic kidney disease (CKD), and uncomplicated hypertension (i.e., without MI, coronary artery disease, diabetes, CKD, and cerebrovascular disease).ResultsWe identified 16,377 patients with markedly elevated BP. They had a mean age of 65.8 (SD: 14.5) years; 54.0% were female; and 69.4%, 19.6%, and 9.6% were White, Black, and Hispanic, respectively. Prior to 90 days of the second visit, 29.8% had no active antihypertensive drug prescription, 20.0% had one drug class prescribed, and 50.2% had two or more drug classes prescribed. Among patients prescribed one antihypertensive drug class, the most common drug class was angiotensin converting enzyme inhibitor (ACEI) or angiotensin receptor blocker (ARB), followed by calcium channel blocker (CCB). Among patients prescribed two antihypertensive drug classes, the most common treatment combinations were ACEI or ARB and thiazide diuretic (21.0%), followed by ACEI or ARB and CCB (20.6%). Guideline-recommended two-drug class combination therapy were prescribed in 54.3% of the treated population, with the highest proportion of 67.0% in patients with a prior MI and the lowest proportion of 48.2% among patients with CKD. Older age, lower body mass index, and lower BP were associated with lower prescription of guideline-recommended combination therapy.ConclusionOnly half of patients with markedly elevated BP were prescribed guideline-recommended antihypertensive combination drugs. Major opportunities exist for improving the guideline adherence of antihypertensive drug prescription in this population.What this Paper AddsSection 1: What is already known on this subject?Hypertension affects nearly one in two adults in the United States, of whom 20% have markedly elevated blood pressure (BP; defined as BP ≥160/100 mmHg). People with markedly elevated BP have increased risks of adverse cardiovascular and kidney events. Clinical guidelines recommend prescribing combination therapy with two or more antihypertensive agents for patients with markedly elevated BP.Section 2: What this study addsThis study quantified the real-world medication guideline adherence among ambulatory patients with markedly elevated BP, using electronic health record data from a large health system in the United States. Prior to 90 days of the second visit with BP ≥160/100 mmHg, nearly 30% of patients had no active antihypertensive drug prescription. Among patients prescribed at least one antihypertensive drug class, guideline-recommended two-drug class combination therapy were prescribed in 54% of patients, with the highest proportion of 67% in patients with a prior myocardial infarction and the lowest proportion of 48% among patients with chronic kidney disease. These findings highlight a large missed opportunity for improving the guideline adherence of antihypertensive drug prescription in this population.
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- 2022
35. Research on Multi-Value Chain Collaborative Production Decision Analysis for Manufacturing Enterprises Based on Ds-Mvc Architecture
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Mingyu Li, Dongxiao Niu, Zhengsen Ji, Yuntian Liu, Xiwen Cui, Jieping Han, and Huanfen Zhang
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- 2022
36. National Trends in Racial and Ethnic Disparities in Antihypertensive Medication Use and Blood Pressure Control Among Adults With Hypertension, 2011-2018
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Jeph Herrin, Yuan Lu, Yuntian Liu, Harlan M. Krumholz, Shiwani Mahajan, Oyere Onuma, Lovedeep Singh Dhingra, Daisy Massey, Cesar Caraballo, and Erica S. Spatz
- Subjects
Blood pressure control ,Adult ,Male ,National Health and Nutrition Examination Survey ,Adolescent ,Ethnic group ,Psychological intervention ,Blood Pressure ,Young Adult ,Internal Medicine ,Ethnicity ,Medicine ,Humans ,Healthcare Disparities ,Antihypertensive Agents ,Antihypertensive medication ,Aged ,Aged, 80 and over ,business.industry ,Racial Groups ,Guideline ,Odds ratio ,Health Status Disparities ,Middle Aged ,Nutrition Surveys ,Health equity ,United States ,Hypertension ,Female ,business ,Demography - Abstract
Poor hypertension awareness and underuse of guideline-recommended medications are critical factors contributing to poor hypertension control. Using data from 8095 hypertensive people aged ≥18 years from the National Health and Nutrition Examination Survey (2011–2018), we examined recent trends in racial and ethnic differences in awareness and antihypertensive medication use, and their association with racial and ethnic differences in hypertension control. Between 2011 and 2018, age-adjusted hypertension awareness declined for Black, Hispanic, and White individuals, but the 3 outcomes increased or did not change for Asian individuals. Compared with White individuals, Black individuals had a similar awareness (odds ratio, 1.20 [0.96–1.45]) and overall treatment rates (1.04 [0.84–1.25]), and received more intensive antihypertensive medication if treated (1.41 [1.27–1.56]), but had a lower control rate (0.72 [0.61–0.83]). Asian and Hispanic individuals had significantly lower awareness rates (0.69 [0.52–0.85] and 0.74 [0.59–0.89]), overall treatment rates (0.72 [0.57–0.88] and 0.69 [0.55–0.82]), received less intensive medication if treated (0.60 [0.50–0.72] and 0.86 [0.75–0.96]), and had lower control rates (0.66 [0.54–0.79] and 0.69 [0.57–0.81]). The racial and ethnic differences in awareness, treatment, and control persisted over the study period and were consistent across age, sex, and income strata. Lower awareness and treatment were significantly associated with lower control in Asian and Hispanic individuals ( P
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- 2021
37. The Challenges of Episodic Office-based Blood Pressure Measurement for the Management of Hypertension
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George C. Linderman, Shiwani Mahajan, Chenxi Huang, Yuan Lu, Harlan M. Krumholz, Yuntian Liu, Erica S. Spatz, Rohan Khera, and Bobak J. Mortazavi
- Subjects
medicine.medical_specialty ,Office based ,Ambulatory blood pressure ,Blood pressure ,business.industry ,Internal medicine ,Coefficient of variation ,medicine ,Population study ,Retrospective cohort study ,Absolute difference ,business ,Cohort study - Abstract
ImportanceClinicians use blood pressure (BP) readings obtained during clinical encounters to detect hypertension and determine the adequacy of treatment. Variations in office-based BP measurements may obscure a hypertension diagnosis or overwhelm a signal of treatment response.ObjectivesTo quantify visit-to-visit variability (VVV) in BP values and its association with patient factors in real-world practice.Design, Setting and, ParticipantsRetrospective cohort analysis of adult patients (age ≥18 years) with at least two outpatient visits in the Yale-New Haven Health System between January 1, 2014 to October 31, 2018.Main Outcome and MeasuresPatient-level measures of VVV included standard deviation (SD) and coefficient of variation (CV) of a given patient’s BP across visits. We introduced a metric to determine the VVV between any two visits (dyad) to characterize the BP information that clinicians have as they formulate their recommendations. Dyad-level measures of VVV included difference, absolute difference, standardized difference, and absolute standardized difference between the two visits of a dyad.ResultsThe study population included 537,245 adults, with a total of 7,721,864 BP measurements. The mean age was 53.4 years (SD of 19.0), 60.4% were women, 69.4% were non-Hispanic White, and 18.1% with hypertension treatment. At the patient level, the mean intra-individual SD and CV were 10.6 mmHg and 0.08 mmHg. At the dyad level, the mean difference, absolute difference, standardized difference, and absolute standardized difference were -0.7 mmHg, 11.6 mmHg, 0 mmHg, and 0.09 mmHg, respectively. Given the observed VVV, if an antihypertensive medication truly reduced a patient’s SBP by 10 mmHg (the average BP-lowering effect reported in previous review), clinicians would expect to observe a reduction of SBP < 5mm Hg at the next visit 36.9% of the time. In the multivariable linear regression model, only 2% of the variance in absolute standardized difference was attributable to patient characteristics.Conclusions and RelevanceThe large VVV poses challenges for diagnosis, treatment, and monitoring of patients with hypertension based on BP readings in outpatient settings, supporting recent guidelines recommending home BP monitoring and ambulatory BP monitoring as out-of-office alternatives to establish diagnosis of hypertension and BP control.KEY POINTSQuestionWhat is the visit-to-visit variability (VVV) in blood pressure (BP) values and its association with patient factors in real-world practice?FindingsIn this retrospective cohort analysis that included 537,245 adults and 7,721,864 office-based BP measurements from a large health system, marked VVV was observed in BP values and the median absolute change between two consecutive visits was about 12 mmHg. The VVV was not significantly associated with patient demographic and clinical characteristics.MeaningThe large VVV poses challenges for diagnosis, treatment, and monitoring of patients with hypertension based on BP readings in outpatient settings, supporting recent guidelines recommending home BP monitoring and ambulatory BP monitoring as out-of-office alternatives to establish a new diagnosis of hypertension and BP control.
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- 2021
38. Trends in Awareness, Antihypertensive Medication Use and Blood Pressure Control by Race and Ethnicity Among Adults with Hypertension in the United States: A National Health and Nutrition Examination Analysis from 2011 to 2018
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Oyere Onuma, Lovedeep Singh Dhingra, Yuan Lu, Shiwani Mahajan, Jeph Herrin, Harlan M. Krumholz, Daisy Massey, Yuntian Liu, Erica S. Spatz, and Cesar Caraballo
- Subjects
Blood pressure control ,Race (biology) ,Blood pressure ,business.industry ,Psychological intervention ,Ethnic group ,Medicine ,Odds ratio ,business ,Confidence interval ,Demography ,Antihypertensive medication - Abstract
ObjectiveTo examine United States (US) trends in racial/ethnic differences in hypertension awareness and antihypertensive medication use, and whether these differences help explain racial/ethnic differences in hypertension control among adults from 2011 to 2018.DesignPopulation-based study.SettingNational Health and Nutrition Examination Survey (NHANES), 2011-2018.ParticipantsA nationally representative sample of US adults aged 18 years or older.Main outcome measuresHypertension awareness was defined as self-reported physician diagnosis of hypertension. Antihypertensive treatment was based on self-reported use of antihypertensive agents. Blood pressure (BP) control was measured systolic BP ResultsThis study included 8,095 adults with hypertension from NHANES 2011-2018. During the study period, age-adjusted hypertension awareness declined from 84.0% (95% confidence interval 79.5 to 86.2) to 77.5% (74.0 to 80.5), hypertension treatment declined from 77.3% (73.4 to 81.1) to 71.4% (69.0 to 73.8) and control rates declined from 51.9% (47.1 to 56.7) to 43.1% (39.7 to 46.5). These declines were consistent for Black, Hispanic, and White individuals, but the three outcomes increased or did not change for Asian individuals. Compared with White individuals, Black individuals did not have a significantly different awareness (odds ratio:1.20 [0.96 to 1.45]) and overall treatment rate (1.04 [0.84 to 1.25]), but received more antihypertensive medications if treated (1.41 [1.27 to 1.56]), and had a lower BP control rate (0.72 [0.61 to 0.83]); Asian and Hispanic individuals had significantly lower awareness rates (0.69 [0.52 to 0.85] and 0.74 [0.59 to 0.89], respectively), overall treatment rates (0.72 [0.57 to 0.88] and 0.69 [0.55 to 0.82]), received fewer medications if treated (0.60 [0.50 to 0.72] and 0.86 [0.75 to 0.96]), and had lower BP control rates (0.66 [0.54 to 0.79] and 0.69 [0.57 to 0.81]). The racial/ethnic differences in awareness, treatment, and BP control persisted over the study period and were consistent across age, sex, and income strata. Lower awareness and treatment were associated with lower BP control in Asian and Hispanic individuals, but not in Black individuals.ConclusionsHypertension awareness, treatment, and control declined from 2011-2018, and this decline was consistent for Black, Hispanic, and White individuals. BP control was worse for Asian, Black, and Hispanic individuals than for White individuals over the entire study period; this was explained partly by differences in awareness and treatment for Asian and Hispanic individuals, but not for Black individuals.What this Paper AddsSection 1: What is already known on this subject?Hypertension control rate has declined in the United States (US) since 2013, and this decline is more pronounced in Black and Hispanic communities.Section 2: What this study addsOur study shows that hypertension awareness, treatment, and control in the US have worsened from 2011 to 2018, and this trend was consistent for Black, Hispanic, and White individuals. Compared with White individuals, Black individuals had similar awareness and overall treatment rates, received more antihypertensive medications if treated, but had a lower control rate; Asian and Hispanic individuals had significantly lower awareness rates, overall treatment rates, received fewer medications if treated, and had lower control rates. Lower awareness and treatment were associated with lower BP control in Asian and Hispanic individuals, but not in Black individuals. These findings highlight the need for interventions to improve awareness and treatment among Asian and Hispanic individuals, and more investigation into the downstream factors that may contribute to the poor hypertension control among Black individuals.
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- 2021
39. Pressure-Tuned Intralayer Exchange in Superlattice-Like MnBi
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Jifeng, Shao, Yuntian, Liu, Meng, Zeng, Jingyuan, Li, Xuefeng, Wu, Xiao-Ming, Ma, Feng, Jin, Ruie, Lu, Yichen, Sun, Mingqiang, Gu, Kedong, Wang, Wenbin, Wu, Liusuo, Wu, Chang, Liu, Qihang, Liu, and Yue, Zhao
- Abstract
The magnetic structures of MnBi
- Published
- 2021
40. Sex-Specific Risk Factors Associated With First Acute Myocardial Infarction in Young Adults
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Yuan, Lu, Shu-Xia, Li, Yuntian, Liu, Fatima, Rodriguez, Karol E, Watson, Rachel P, Dreyer, Rohan, Khera, Karthik, Murugiah, Gail, D'Onofrio, Erica S, Spatz, Khurram, Nasir, Frederick A, Masoudi, and Harlan M, Krumholz
- Subjects
Male ,Young Adult ,Risk Factors ,Case-Control Studies ,Hypercholesterolemia ,Hypertension ,Diabetes Mellitus ,Myocardial Infarction ,Humans ,Female ,General Medicine ,Nutrition Surveys - Abstract
An increasing proportion of people in the US hospitalized for acute myocardial infarction (AMI) are younger than 55 years, with the largest increase in young women. Effective prevention requires an understanding of risk factors associated with risk of AMI in young women compared with men.To assess the sex-specific associations of demographic, clinical, and psychosocial risk factors with first AMI among adults younger than 55 years, overall, and by AMI subtype.This study used a case-control design with 2264 patients with AMI, aged 18 to 55 years, from the VIRGO (Variation in Recovery: Role of Gender on Outcomes of Young AMI Patients) study and 2264 population-based controls matched for age, sex, and race and ethnicity from the National Health and Nutrition Examination Survey from 2008 to 2012. Data were analyzed from April 2020 to November 2021.A wide range of demographic, clinical, and psychosocial risk factors.Odds ratios (ORs) and population attributable fractions (PAF) for first AMI associated with demographic, clinical, and psychosocial risk factors.Of the 4528 case patients and matched controls, 3122 (68.9%) were women, and the median (IQR) age was 48 (44-52) years. Seven risk factors (diabetes [OR, 3.59 (95% CI, 2.72-4.74) in women vs 1.76 (1.19-2.60) in men], depression [OR, 3.09 (95% CI, 2.37-4.04) in women vs 1.77 (1.15-2.73) in men], hypertension [OR, 2.87 (95% CI, 2.31-3.57) in women vs 2.19 (1.65-2.90) in men], current smoking [OR, 3.28 (95% CI, 2.65-4.07) in women vs 3.28 (2.65-4.07) in men], family history of premature myocardial infarction [OR, 1.48 (95% CI, 1.17-1.88) in women vs 2.42 (1.71-3.41) in men], low household income [OR, 1.79 (95% CI, 1.28-2.50) in women vs 1.35 (0.82-2.23) in men], hypercholesterolemia [OR, 1.02 (95% CI, 0.81-1.29) in women vs 2.16 (1.49-3.15) in men]) collectively accounted for the majority of the total risk of AMI in women (83.9%) and men (85.1%). There were significant sex differences in risk factor associations: hypertension, depression, diabetes, current smoking, and family history of diabetes had stronger associations with AMI in young women, whereas hypercholesterolemia had a stronger association in young men. Risk factor profiles varied by AMI subtype, and traditional cardiovascular risk factors had higher prevalence and stronger ORs for type 1 AMI compared with other AMI subtypes.In this case-control study, 7 risk factors, many potentially modifiable, accounted for 85% of the risk of first AMI in young women and men. Significant differences in risk factor profiles and risk factor associations existed by sex and by AMI subtype. These findings suggest the need for sex-specific strategies in risk factor modification and prevention of AMI in young adults. Further research is needed to improve risk assessment of AMI subtypes.
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- 2022
41. Stability Improvement of Cascaded Power Conversion Systems Based on Hamiltonian Energy Control Theory
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Yigeng Huangfu, Shengzhao Pang, Yuntian Liu, Guangzhao Luo, Fei Gao, Saeid Aghaei Hashjin, Jean-Philippe Martin, Serge Pierfederici, Babak Nahid-Mobarakeh, Laboratoire Énergies et Mécanique Théorique et Appliquée (LEMTA ), Université de Lorraine (UL)-Centre National de la Recherche Scientifique (CNRS), McMaster University [Hamilton, Ontario], Groupe de Recherche en Energie Electrique de Nancy (GREEN), Université de Lorraine (UL), ESME Sudria [Paris], Northwestern Polytechnical University [Xi'an] (NPU), Franche-Comté Électronique Mécanique, Thermique et Optique - Sciences et Technologies (UMR 6174) (FEMTO-ST), Université de Technologie de Belfort-Montbeliard (UTBM)-Ecole Nationale Supérieure de Mécanique et des Microtechniques (ENSMM)-Université de Franche-Comté (UFC), and Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC)-Centre National de la Recherche Scientifique (CNRS)
- Subjects
Lyapunov function ,Hamiltonian mechanics ,0209 industrial biotechnology ,Computer science ,020208 electrical & electronic engineering ,Passivity ,[SPI.NRJ]Engineering Sciences [physics]/Electric power ,02 engineering and technology ,LC circuit ,Converters ,Industrial and Manufacturing Engineering ,[SPI.AUTO]Engineering Sciences [physics]/Automatic ,symbols.namesake ,Superposition principle ,020901 industrial engineering & automation ,Control and Systems Engineering ,Control theory ,Cascade ,0202 electrical engineering, electronic engineering, information engineering ,symbols ,[PHYS.MECA.THER]Physics [physics]/Mechanics [physics]/Thermics [physics.class-ph] ,[PHYS.MECA.MEFL]Physics [physics]/Mechanics [physics]/Fluid mechanics [physics.class-ph] ,Electrical and Electronic Engineering ,Hamiltonian (control theory) - Abstract
International audience; It is well known that the interaction between cascaded individually designed power conversion systems can cause instability. To overcome this issue, a Hamiltonian energy control scheme is proposed, which is based on passivity control theory and port-controlled Hamiltonian framework. A complementary PI adjustment term is also included in the control algorithm to eliminate the steady-state output voltage error caused by the parameter uncertainty. The proposed control approach is applied to three different cascade structures. First, the cascade structure between dc/dc converters is considered, and the detailed controller design is given. Second, the cascade connection of a single converter and its LC filter is studied. By placing the LC filter into the Hamiltonian model of the controlled converter system, the dynamic and potential instability caused by the filter can be adjusted. Finally, the cascade structure between subsystems including filters and converters, which are common in microgrids, is studied. By using the Hamiltonian function (storage function) as the Lyapunov function candidate, the large-signal stability of each controlled converter system is proved. When the cascade structure contains multiple controlled converter systems, the stability of the entire cascaded system is guaranteed by the superposition of multiple Lyapunov functions. A 3.5 kW 220-270-350 V test bench is built in the laboratory to demonstrate the application of the proposed control approach to these three cascade structures.
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- 2021
42. An Improved State Machine Strategy for Fuel-Cell-Based Hybrid Electric Vehicles
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Zehua Liang, Yuxiang Zhang, Yuntian Liu, Dongdong Zhao, Hanbin Dang, and Haiyan Li
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Battery (electricity) ,Power management ,Finite-state machine ,business.product_category ,Stack (abstract data type) ,Computer science ,Electric vehicle ,Fuel cells ,Hydrogen consumption ,Hybrid power ,business ,Automotive engineering ,Power (physics) - Abstract
In this paper, a hybrid power system for electric vehicle with fuel cell stack and Lithium-ion battery is designed and power converters transferring power are modeled. Besides, an improved state machine strategy is developed to split the power produced by power sources. The rules are designed to avoid battery overcharging in high SOC and over discharging in low SOC, and avoid charge and discharge frequently in normal SOC area while decreasing the hydrogen consumption. The simulation results verify that the improved state machine strategy performs better than traditional state machine strategy.
- Published
- 2020
43. A Novel Diagnosis Method of Proton Exchange Membrane Fuel Cells Based on the PCA and XGBoost Algorithm
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Renyou Xie, Rui Ma, Yuntian Liu, Haiyan Li, Dongdong Zhao, and Hanbin Dang
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Boosting (machine learning) ,Computer science ,business.industry ,020209 energy ,Proton exchange membrane fuel cell ,02 engineering and technology ,021001 nanoscience & nanotechnology ,Renewable energy ,Reliability engineering ,Principal component analysis ,0202 electrical engineering, electronic engineering, information engineering ,0210 nano-technology ,business ,Leakage (electronics) ,Curse of dimensionality - Abstract
As a renewable and efficient power source, proton exchange membrane fuel cells (PEMFCs) are receiving more and more attention from the world, but it still has shortcomings with poor durability and insufficient reliability, so the purpose of this paper is to effectively improve the reliability and durability of PEMFCs by a data-driven fault diagnosis method. In this method, principal component analysis (PCA) is first adopted to reduce the dimensionality of fault data. Then, a classification method named eXtreme Gradient Boosting (XGBoost) which based on boosting algorithm is used to classify these data. In the end, the experiment is proposed to verify the diagnostic performance of this method. The result shows that the method can effectively identify four healthy states of membrane drying failure, hydrogen leakage failure, normal state as well as unknown state, the diagnostic accuracy can reach 99.72%, and the diagnosis period is 0.17751 s, which is suitable for online implementation.
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- 2020
44. COMPREHENSIVE COMPARATIVE EFFECTIVENESS AND SAFETY OF FIRST-LINE CALCIUM CHANNEL BLOCKER MONOTHERAPY IN HYPERTENSIVE PATIENTS: A LARGE-SCALE MULTINATIONAL PARTICIPANT-LEVEL ASSESSMENT
- Author
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Yuan Lu, Rohan Khera, Yuntian Liu, Ruijun Chen, Martijn Schuemie, George Hripcsak, Marc Suchard, and Harlan M. Krumholz
- Subjects
Cardiology and Cardiovascular Medicine - Published
- 2022
45. COMPREHENSIVE COMPARATIVE EFFECTIVENESS AND SAFETY OF FIRST-LINE ANTIHYPERTENSIVE MONOTHERAPY IN HYPERTENSIVE PATIENTS: A LARGE-SCALE MULTINATIONAL PARTICIPANT-LEVEL ASSESSMENT
- Author
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Yuan Lu, Rohan Khera, Yuntian Liu, Ruijun Chen, Martijn Schuemie, George Hripcsak, Marc Suchard, and Harlan M. Krumholz
- Subjects
Cardiology and Cardiovascular Medicine - Published
- 2022
46. Distinct Topological Surface States on the Two Terminations of MnBi4Te7
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Maohai Xie, Hongyi Sun, Chun-Sheng Zhou, Xuefeng Wu, Yu Zhang, Xiaoming Ma, Qiaoming Wang, Qihang Liu, Yue Zhao, Jifeng Shao, Yue Feng, Shiv Kumar, Chaoyu Chen, Chang Liu, Pengfei Liu, Yuntian Liu, Koji Miyamoto, Kenya Shimada, Jiayu Li, Taichi Okuda, Kedong Wang, Yu-Jie Hao, and Eike F. Schwier
- Subjects
Surface (mathematics) ,Materials science ,Condensed matter physics ,Topological insulator ,0103 physical sciences ,General Physics and Astronomy ,010306 general physics ,01 natural sciences ,010305 fluids & plasmas ,Surface states - Abstract
Experiments reveal that unusual surface behavior at the terminations of a recently discovered magnetic topological insulator depends on the interplay between different building blocks within the material.
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- 2020
47. Pressure-tuned intralayer exchange in superlattice-like MnBi2Te4/(Bi2Te3)n topological insulators
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Xiaoming Ma, Jingyuan Li, Meng Zeng, Chang Liu, Yuntian Liu, Feng Jin, Ruie Lu, Yue Zhao, Qihang Liu, Wenbin Wu, Mingqiang Gu, Jifeng Shao, Yichen Sun, Kedong Wang, Xuefeng Wu, and Liusuo Wu
- Subjects
Phase transition ,Condensed Matter - Materials Science ,Materials science ,Condensed matter physics ,Mechanical Engineering ,Superlattice ,Hydrostatic pressure ,Materials Science (cond-mat.mtrl-sci) ,FOS: Physical sciences ,Bioengineering ,General Chemistry ,Condensed Matter Physics ,Ferromagnetism ,Topological insulator ,Antiferromagnetism ,General Materials Science ,Condensed Matter::Strongly Correlated Electrons ,Saturation (magnetic) ,Néel temperature - Abstract
The magnetic structures of MnBi2Te4(Bi2Te3)n can be manipulated by tuning the interlayer coupling via the number of Bi2Te3 spacer layers n, while the intralayer ferromagnetic (FM) exchange coupling is considered too robust to control. By applying hydrostatic pressure up to 3.5 GPa, we discover opposite responses of magnetic properties for n = 1 and 2. MnBi4Te7 stays at A-type antiferromagnetic (AFM) phase with a decreasing N\'eel temperature and an increasing saturation field. In sharp contrast, MnBi6Te10 experiences a phase transition from A-type AFM to a quasi-two-dimensional FM state with a suppressed saturation field under pressure. First-principles calculations reveal the essential role of intralayer exchange coupling from lattice compression in determining these magnetic properties. Such magnetic phase transition is also observed in 20% Sb-doped MnBi6Te10 due to the in-plane lattice compression., Comment: 20 pages, 5 figures
- Published
- 2020
- Full Text
- View/download PDF
48. Optimal Analysis of Transmission Lines Using Ant Colony-Improved Matter-Element Extension Method
- Author
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Jingqi Sun and Yuntian Liu
- Subjects
History ,Electric power transmission ,Matter element ,Extension method ,Ant colony ,Algorithm ,Computer Science Applications ,Education ,Mathematics - Abstract
Traditional transmission line design often relies on human experience and is highly subjective. In order to realize intelligent transmission line route optimization, this paper relies on the established geographic information system platform, selects 119°14’50” east longitude to 119°17’56” east longitude, and 31°57’34” north latitude to 31°54’49 north latitude. For the rectangular area of”, first rasterize the area into a 20*20 grid according to the rasterization model, then enter the coordinates of the avoidance area, and optimize the shortest transmission line path according to the ant colony algorithm. Then based on the rasterized matter-element scheme, an improved matter-element extension evaluation method is used to comprehensively evaluate the feasible points around the matter-element node of each path, and the point with the best economic efficiency is selected as the transit point of the transmission line. Optimization of the entire transmission line. The results of the numerical example analysis prove that the method has a better auxiliary decision-making effect on the erection of transmission lines.
- Published
- 2021
49. Small Signal Analysis and Control Design of Snubberless Naturally Clamped ZCS/ZVS Current-Fed Half-Bridge DC/DC Converter for EV
- Author
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Yuntian Liu, Dongdong Zhao, Qingchao Zhang, Yigeng Huangfu, Qian Li, and Minchi Xie
- Subjects
Physics ,Signal processing ,business.product_category ,020208 electrical & electronic engineering ,010102 general mathematics ,02 engineering and technology ,Inductor ,01 natural sciences ,Power (physics) ,Inductance ,Small-signal model ,Control theory ,Electric vehicle ,0202 electrical engineering, electronic engineering, information engineering ,0101 mathematics ,business ,Voltage - Abstract
This paper presents a systematic derivation of a small signal model of current-fed half bridge isolated dc/dc converter for the hybrid electric vehicle based on the lithium battery and fuel cell. The reflected output voltage across the power semiconductor devices can naturally be clamped at V°/n by a secondary-modulation strategy without any additional circuit, which can reduce footprints and cost. Moreover, the soft switch of all can be achieved resulting in low switching losses and higher efficiency due to ZCS/ZVS. In order to maintain the constant bus voltage and the balanced two-way inductor current, a small signal model using state-space averaging technique is deduced and the dual closed loop controller is designed in detail. The co-simulation of PSIM and MATLAB/SIMULINK is used to verify the effectiveness of the controller when the load step-changes in case of the different input voltage.
- Published
- 2018
50. Optimization of Transmission Lines in Substations Using Ant Colony Optimization Algorithm
- Author
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Guan Weiya, Yuntian Liu, Liwei Qiao, and Ning Xu
- Subjects
History ,Electric power transmission ,Computer science ,Ant colony optimization algorithms ,Algorithm ,Computer Science Applications ,Education - Abstract
In the design process of the transmission line of the traditional substation system, the plans and decisions often made by people, resulting in unsatisfactory line design results, which are not the most economical optimal results, and they are not even considered in the preliminary planning. Going to areas where lines cannot be erected has caused slow progress and poor accuracy in the feasibility study stage. This paper combines the ant colony intelligent algorithm with the geographic information system, and proposes a substation transmission line optimization model, which outputs the optimal path by inputting geographic information data. This model analyzes the entire process of the transmission line design stage and realizes the intelligent line selection. The analysis of the example in the article proves that the model has a better auxiliary function for the work of the substation line planning stage.
- Published
- 2021
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